메뉴 건너뛰기




Volumn 16, Issue 4, 1997, Pages 717-725

Heregulin-stimulated acetylcholine receptor gene expression in muscle: Requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity

Author keywords

Acetylcholine receptor; Heregulin; Membrane depolarization; Mitogen activated protein kinase; p70S6 kinase

Indexed keywords

CHOLINERGIC RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; RECEPTOR SUBUNIT; WORTMANNIN;

EID: 0031046948     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.4.717     Document Type: Article
Times cited : (111)

References (44)
  • 1
    • 0029053716 scopus 로고
    • Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
    • Alimandi, M., Romano, A., Curia, M.C., Muraro, R., Fedi, P., Aaronson, S.A., DiFiore, P.P. and Kraus, M.H. (1995) Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene, 10, 1813-1821.
    • (1995) Oncogene , vol.10 , pp. 1813-1821
    • Alimandi, M.1    Romano, A.2    Curia, M.C.3    Muraro, R.4    Fedi, P.5    Aaronson, S.A.6    DiFiore, P.P.7    Kraus, M.H.8
  • 2
    • 0029089927 scopus 로고
    • ErbB3 and ErbB2/ neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: Differential expression at the endplate
    • Altiok, N., Bessereau, J.-L. and Changeux, J.-P. (1995) ErbB3 and ErbB2/ neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate. EMBO J., 14, 4258-4266.
    • (1995) EMBO J. , vol.14 , pp. 4258-4266
    • Altiok, N.1    Bessereau, J.-L.2    Changeux, J.-P.3
  • 3
    • 0028175091 scopus 로고
    • Raf meets Ras: Completing the framework of a signal transduction pathway
    • Avruch, J., Zhang, X.F. and Kyriakis, J.M. (1994) Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem. Sci., 19, 279-283.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 279-283
    • Avruch, J.1    Zhang, X.F.2    Kyriakis, J.M.3
  • 4
    • 0027153103 scopus 로고
    • Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adaptor protein, and Sos nucleotide exchange factor
    • Buday, L. and Downward, J. (1993) Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adaptor protein, and Sos nucleotide exchange factor. Cell, 73, 611-620
    • (1993) Cell , vol.73 , pp. 611-620
    • Buday, L.1    Downward, J.2
  • 5
    • 0028949081 scopus 로고
    • Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3
    • Carraway, K.L., III, Soltoff, S.R. Diamonti, A.J. and Cantley, L.C. (1995) Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3. J. Biol. Chem., 270, 7111-7116.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7111-7116
    • Carraway III, K.L.1    Soltoff, S.R.2    Diamonti, A.J.3    Cantley, L.C.4
  • 8
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth-dependent activation of and signalling by the 70 kDa S6 protein kinases
    • Chung, J., Kuo, J.C., Crabtree, C.R. and Blenis, J. (1992) Rapamycin-FKBP specifically blocks growth-dependent activation of and signalling by the 70 kDa S6 protein kinases. Cell, 69, 1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, J.C.2    Crabtree, C.R.3    Blenis, J.4
  • 9
    • 0028178928 scopus 로고
    • PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3OH kinase
    • Chung, J., Grammer, T.C., Lemon, K.P., Kazlauskas, A. and Blenis, J. (1994) PDGF-and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3OH kinase. Nature, 370, 71-75.
    • (1994) Nature , vol.370 , pp. 71-75
    • Chung, J.1    Grammer, T.C.2    Lemon, K.P.3    Kazlauskas, A.4    Blenis, J.5
  • 10
    • 0025181418 scopus 로고
    • Okadaic acid: A new probe for the study of cellular regulation
    • Cohen, P., Holmes, C.F.B. and Tsuikitani, Y. (1990) Okadaic acid: a new probe for the study of cellular regulation. Trends Biol. Sci., 15, 98-102.
    • (1990) Trends Biol. Sci. , vol.15 , pp. 98-102
    • Cohen, P.1    Holmes, C.F.B.2    Tsuikitani, Y.3
  • 11
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis, R.J. (1993) The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem., 268, 14553-14556.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 12
    • 0028935061 scopus 로고
    • Acetylcholine receptor gene expression at the developing neuromuscular junction
    • Duclert, A. and Changeux, J.-P. (1995) Acetylcholine receptor gene expression at the developing neuromuscular junction. Physiol. Rev., 75, 339-368.
    • (1995) Physiol. Rev. , vol.75 , pp. 339-368
    • Duclert, A.1    Changeux, J.-P.2
  • 13
    • 0027526321 scopus 로고
    • ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family
    • Falls, D.L., Rosen, K.M., Corfas, G., Lane, W.S. and Fischbach, G.D. (1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell, 72, 801-815.
    • (1993) Cell , vol.72 , pp. 801-815
    • Falls, D.L.1    Rosen, K.M.2    Corfas, G.3    Lane, W.S.4    Fischbach, G.D.5
  • 14
    • 0028120910 scopus 로고
    • Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase Cγ or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members
    • Fedi, P., Pierce, J.H., DiFiore, P.P. and Kraus, M.H. (1994) Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase Cγ or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. Mol. Cell. Biol., 14, 492-500.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 492-500
    • Fedi, P.1    Pierce, J.H.2    DiFiore, P.P.3    Kraus, M.H.4
  • 15
    • 0028338460 scopus 로고
    • Nerve growth factor activates a ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB
    • Ginty, D.D., Bonni, A. and Greenberg, M.E. (1994) Nerve growth factor activates a ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell, 77, 713-725.
    • (1994) Cell , vol.77 , pp. 713-725
    • Ginty, D.D.1    Bonni, A.2    Greenberg, M.E.3
  • 16
    • 0026659262 scopus 로고
    • erbB2
    • erbB2. Science, 256, 1205-1210.
    • (1992) Science , vol.256 , pp. 1205-1210
    • Holmes, W.E.1
  • 17
    • 0028075105 scopus 로고
    • Depolarization-transcription signals in skeletal muscle use calcium flux through L channels, but bypass the sarcoplasmic reticulum
    • Huang, C.F., Flucher, B.E., Schmidt, M.M., Stroud, S.K. and Schmidt, J. (1994) Depolarization-transcription signals in skeletal muscle use calcium flux through L channels, but bypass the sarcoplasmic reticulum. Neuron, 13, 167-177.
    • (1994) Neuron , vol.13 , pp. 167-177
    • Huang, C.F.1    Flucher, B.E.2    Schmidt, M.M.3    Stroud, S.K.4    Schmidt, J.5
  • 18
    • 0028895952 scopus 로고
    • Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression
    • Jo, S.A., Zhu, X., Marchionni, M.A. and Burden, S. (1995) Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression. Nature, 373, 158-161.
    • (1995) Nature , vol.373 , pp. 158-161
    • Jo, S.A.1    Zhu, X.2    Marchionni, M.A.3    Burden, S.4
  • 19
    • 0028486018 scopus 로고
    • Phospathidylinositol 3-kinase
    • Kapeller, R. and Cantley, L.C. (1994) Phospathidylinositol 3-kinase. Bioassays, 16, 565-576.
    • (1994) Bioassays , vol.16 , pp. 565-576
    • Kapeller, R.1    Cantley, L.C.2
  • 21
    • 0022100936 scopus 로고
    • Activity regulates the levels of acetylcholine receptor α-subunit mRNA in cultured chicken myotubes
    • Klarsfeld, A. and Changeux, J.-P. (1985) Activity regulates the levels of acetylcholine receptor α-subunit mRNA in cultured chicken myotubes. Proc. Natl Acad. Sci. USA, 82, 4558-4562.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 4558-4562
    • Klarsfeld, A.1    Changeux, J.-P.2
  • 23
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus, M.H., Issing, W., Miki, T., Popescu, N.C. and Aaronson, S.A. (1989) Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl Acad. Sci. USA, 86, 9193-9197.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 24
    • 0029125140 scopus 로고
    • Local neurotrophic repression of gene transcripts encoding fetal AChRs at neuromuscular synapses
    • Kues, W.A., Brenner, H.R., Sakmann, B. and Witzemann, V. (1995) Local neurotrophic repression of gene transcripts encoding fetal AChRs at neuromuscular synapses. J. Cell Biol., 130, 946-957.
    • (1995) J. Cell Biol. , vol.130 , pp. 946-957
    • Kues, W.A.1    Brenner, H.R.2    Sakmann, B.3    Witzemann, V.4
  • 25
    • 0026340696 scopus 로고
    • Phorbol esters inhibit the activity of the chicken acetylcholine receptor α-subunit gene promoter
    • Laufer, R., Klarsfeld, A. and Changeux, J.-P. (1991) Phorbol esters inhibit the activity of the chicken acetylcholine receptor α-subunit gene promoter. Eur. J. Biochem., 202, 813-818.
    • (1991) Eur. J. Biochem. , vol.202 , pp. 813-818
    • Laufer, R.1    Klarsfeld, A.2    Changeux, J.-P.3
  • 26
    • 0027530106 scopus 로고
    • Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
    • Marchionni, M.A. et al. (1993) Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system. Nature, 362, 312-318.
    • (1993) Nature , vol.362 , pp. 312-318
    • Marchionni, M.A.1
  • 27
    • 0028932436 scopus 로고
    • ErbB-3 mediates differential mitogenic effects of NDF/heregulin isoforms on mouse keratinocytes
    • Marikovsky, M., Lavi, S., Pinkars-Kramarski, R., Karunagaran, D., Liu, N., Wen, D. and Yarden, Y. (1995) ErbB-3 mediates differential mitogenic effects of NDF/heregulin isoforms on mouse keratinocytes. Oncogene, 19, 1403-1411.
    • (1995) Oncogene , vol.19 , pp. 1403-1411
    • Marikovsky, M.1    Lavi, S.2    Pinkars-Kramarski, R.3    Karunagaran, D.4    Liu, N.5    Wen, D.6    Yarden, Y.7
  • 28
    • 0028796895 scopus 로고
    • NDF/heregulin activates MAP kinase and p70/85 S6 kinase during proliferation or differentiation of mammary epithelial cells
    • Marte, B.M., Graus-Porta, D., Jeschke, M., Fabbro, D., Hynes, N.E. and Taverna, D. (1995) NDF/heregulin activates MAP kinase and p70/85 S6 kinase during proliferation or differentiation of mammary epithelial cells. Oncogene, 10, 167-175.
    • (1995) Oncogene , vol.10 , pp. 167-175
    • Marte, B.M.1    Graus-Porta, D.2    Jeschke, M.3    Fabbro, D.4    Hynes, N.E.5    Taverna, D.6
  • 29
    • 0028846281 scopus 로고
    • Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, erbB2 and erbB3, in developing mammalian muscle
    • Moscoso, L.M., Chu, G.C., Gautam, M., Noakes, P.G., Merlie, J.P. and Sanes, J.R. (1995) Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, erbB2 and erbB3, in developing mammalian muscle. Dev. Biol., 172, 158-169.
    • (1995) Dev. Biol. , vol.172 , pp. 158-169
    • Moscoso, L.M.1    Chu, G.C.2    Gautam, M.3    Noakes, P.G.4    Merlie, J.P.5    Sanes, J.R.6
  • 30
    • 0028859279 scopus 로고
    • Protein modules and signalling networks
    • Pawson, T. (1995) Protein modules and signalling networks. Nature, 373, 573-580.
    • (1995) Nature , vol.373 , pp. 573-580
    • Pawson, T.1
  • 31
    • 0026776424 scopus 로고
    • Isolation of the Neu/HER-2 stimulatory ligand: A 44 kDa glycoprotein that induces differentiation of mammary tumor cells
    • Peles, E., Bacus, S.S., Koski, R.A., Lu, H.S., Wen, D., Ogden, S.G., Levy, R.B. and Yarden, Y. (1992). Isolation of the Neu/HER-2 stimulatory ligand: a 44 kDa glycoprotein that induces differentiation of mammary tumor cells. Cell, 69, 205-216.
    • (1992) Cell , vol.69 , pp. 205-216
    • Peles, E.1    Bacus, S.S.2    Koski, R.A.3    Lu, H.S.4    Wen, D.5    Ogden, S.G.6    Levy, R.B.7    Yarden, Y.8
  • 33
    • 0028216712 scopus 로고
    • Identification of c-erbB-3 binding sites for phosphatidylinositol 3′-kinase and SHC using an EGF receptor/c-erbB-3 chimera
    • Prigent, S.A. and Gullick, W.J. (1994) Identification of c-erbB-3 binding sites for phosphatidylinositol 3′-kinase and SHC using an EGF receptor/c-erbB-3 chimera. EMBO J., 13, 2831-2841.
    • (1994) EMBO J. , vol.13 , pp. 2831-2841
    • Prigent, S.A.1    Gullick, W.J.2
  • 34
    • 0029915031 scopus 로고    scopus 로고
    • p70S6 kinase: An enigma with variations
    • Proud, C.G. (1996) p70S6 kinase: an enigma with variations. Trends Biochem. Sci., 21, 181-185.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 181-185
    • Proud, C.G.1
  • 35
    • 0027385031 scopus 로고
    • A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity
    • Rivera, V.M., Miranti, C.K., Misra, R.P., Ginty, D.D., Chen, R.H., Blenis, J. and Greenberg, M.E. (1993) A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol. Cell. Biol., 13, 6260-6273
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6260-6273
    • Rivera, V.M.1    Miranti, C.K.2    Misra, R.P.3    Ginty, D.D.4    Chen, R.H.5    Blenis, J.6    Greenberg, M.E.7
  • 36
    • 0026678172 scopus 로고
    • Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
    • Rozakis-Adcock, M. et al. (1992) Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature, 360, 689-692.
    • (1992) Nature , vol.360 , pp. 689-692
    • Rozakis-Adcock, M.1
  • 37
    • 0028907351 scopus 로고
    • Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis
    • Sale, E.M., Atkinson, P.G.P. and Sale, G.J. (1995) Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis. EMBO J., 14, 674-684.
    • (1995) EMBO J. , vol.14 , pp. 674-684
    • Sale, E.M.1    Atkinson, P.G.P.2    Sale, G.J.3
  • 39
    • 0028358856 scopus 로고
    • Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin
    • Sliwkowski, M.X. et al. (1994) Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin. J. Biol. Chem., 269, 14661-14665.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14661-14665
    • Sliwkowski, M.X.1
  • 40
    • 0028302018 scopus 로고
    • ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
    • Soltoff, S.P., Carraway, K.L., III, Prigent, S.A., Gullick, W.G. and Cantley, L.C. (1994) ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol. Cell. Biol., 14, 3550-3558.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway III, K.L.2    Prigent, S.A.3    Gullick, W.G.4    Cantley, L.C.5
  • 41
    • 0027403027 scopus 로고
    • SH2 domains recognize specific phosphopeptide sequences
    • Songyang, Z. et al. (1994) SH2 domains recognize specific phosphopeptide sequences. Cell. 72, 767-778.
    • (1994) Cell. , vol.72 , pp. 767-778
    • Songyang, Z.1
  • 42
    • 0029977261 scopus 로고    scopus 로고
    • ARIA/HRG regulates AChR ε-subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway
    • Tansey, M.G., Chu, G.C. and Merlie, J.P. (1996) ARIA/HRG regulates AChR ε-subunit gene expression at the neuromuscular synapse via activation of phosphatidylinositol 3-kinase and Ras/MAPK pathway. J. Cell. Biol., 134, 465-476.
    • (1996) J. Cell. Biol. , vol.134 , pp. 465-476
    • Tansey, M.G.1    Chu, G.C.2    Merlie, J.P.3
  • 43
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
    • Ui, M., Okada, T., Hazeki, K. and Hazeki, O. (1995) Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biol. Sci., 20, 303-307.
    • (1995) Trends Biol. Sci. , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 44
    • 0028971642 scopus 로고
    • Neuregulin receptors erbB3 and erbB4 are localized at neuromuscular synapses
    • Zhu, X.J., Lai, C., Thomas, S. and Burden, S.J. (1995) Neuregulin receptors erbB3 and erbB4 are localized at neuromuscular synapses. EMBO J., 14, 5842-5848.
    • (1995) EMBO J. , vol.14 , pp. 5842-5848
    • Zhu, X.J.1    Lai, C.2    Thomas, S.3    Burden, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.