Intraneuronal aluminum potentiates iron-induced oxidative stress in cultured rat hippocampal neurons

Brain Research

Volumn 743, Issue 1-2, 1996, Pages 271-277

  Xie, Charles X ^a   Mattson, Mark P ^b   Lovell, Mark A ^a,b   Yokel, Robert A ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c University of Kentucky   (United States)

Author keywords

2,7 dichlorofluorescin diacetate; aluminum; confocal laser scanning microscopy; hippocampal neuron; iron; laser microprobe mass spectrometry; oxidative stress; reactive oxygen species

Indexed keywords

ALUMINUM; IRON; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; MASS SPECTROMETRY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ALUMINUM; ANALYSIS OF VARIANCE; ANIMALS; CALCIMYCIN; CELL SURVIVAL; CELLS, CULTURED; DRUG SYNERGISM; HIPPOCAMPUS; IONOPHORES; IRON; NEURONS; NEUROTOXINS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030471998     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01055-4     Document Type: Article

References (45)

1. Abreo, K. and Glass, J., Cellular, biochemical, and molecular mechanisms of aluminum toxicity, Nephrol. Dial. Transplant Suppl., 1 (1993) 5-11.
2. Alfrey, A.C., Hegg, A. and Craswell, P., Metabolism and toxicity of aluminum in renal failure, Am. J. Clin. Nutr., 33 (1980) 1509-1516.
3. Bass, D.A., Parce, J.W., Dechatelet, L.R., Szejda, P., Seeds, M.C. and Thomas, M., Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation, J. Immunol., 130 (1983) 1910-1917.
4. Benzi, G. and Moretti, A., Are reactive oxygen species involved in Alzheimer's disease?, Neurobiol Aging, 16 (1995) 661-674.
5. Chainy, G.B.N., Sahoo, A. and Swain, C., Effect of aluminum on lipid peroxidation of cerebral hemisphere of chick, Bull. Environ. Contam. Toxicol., 50 (1993) 85-91.
6. Cheng, B. and Mattson, M.P., NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis, Neuron, 7 (1991) 1031-1041.
7. Cheville, N.F., Ultrastructural Pathology: An Introduction to Interpretation, Iowa State University Press, Ames, IA, 1994.
8. Cohen, G., Oxygen radical and Parkinson's disease. In R. Halliwell (Ed.), Oxygen Radical and Tissue Injury, FASEB, Bethesda, 1988, pp. 130-135.
9. Fraga, C.G., Oteiza, P.I., Golub, M.S. and Gershwin, M.E., Effects of aluminum on brain lipid peroxidation, Toxicol. Lett., 51 (1990) 213-219.
10. Galle, P., Chatel, M., Berry, J.P. and Menault, F., Progressive myoclonic encephalopathy in dialysis patients: presence of high concentration of aluminium in the lysosomes of the cerebral cells, La Nouv. Presse Med., 8 (1979) 4091-4094.
11. Golub, M.S., Han, B., Keen, C.L. and Gershwin, M.E., Effects of dietary aluminum excess and manganese deficiency on neurobehavioral endpoints in adult mice, Toxicol. Appl. Pharmacol., 112 (1992) 154-160.
12. Good, P.F., Olanow, C.W. and Perl, D.P., Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: a LAMMA study, Brain Res., 593 (1992) 343-346.
13. Goodman, Y. and Mattson, M.P., Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury, Exp. Neurol., 128 (1994) 1-12.
14. Gutteridge, J.M.C., Quinlan, G.J., Clark, I. and Halliwell, B., Aluminum salts accelerate peroxidation of membrane lipids stimulated by iron salts, Biochim. Biophys. Acta, 835 (1985) 441-447.
15. Halliwell, B. and Gutteridge, J.M.C., Free Radicals in Biology and Medicine, Clarendon Press, Oxford, 1989.
16. Harrington, C.R., Wischik, C.M., McArthur, F.K., Taylor, G.A., Edwardson, J.A. and Candy, J.M., Alzheimer's-disease-like changes in tau protein processing: Association with aluminum accumulation in brain of renal dialysis patients, Lancet, 343 (1994) 993.
17. Johnston, H.B., Thomas, S.M. and Atterwill, C.K., Aluminum and iron induced metabolic changes in neuroblastoma cell lines and rat primary neural culture, Toxic. In Vitro, 7 (1993) 229-233.
18. Joshi, J.G., Aluminum, a neurotoxin which affects diverse metabolic reactions, BioFactors, 2 (1990) 163-169.
19. Kawahara, M., Muramoto, K., Kobayashi, K., Mori, H. and Kuroda, Y., Aluminum promotes the aggregation of Alzheimer's amyloid β-protein in vitro, Biochem. Biophys. Res. Commun., 198 (1994) 531-535.
20. Kong, S., Lionchev, S. and Fridovich, I., Aluminum(III) facilitates the oxidation of NADH by the superoxide anion, Free Radical Biol. Med., 13 (1982) 79-81.
21. Kuroda, Y., Kobayashi, K., Ichikawa, M., Kawahara, M. and Muramoto, K., Application of long-term cultured neurons in aging and neurological research: aluminum neurotoxicity, synaptic degeneration and Alzheimer's disease, Gerontology, 41 (1995) 2-6.
22. Linss, V.W., Martin, R., Stein, G., Bräunlich, H. and Fleck, C., Electron microscopical evidence of aluminum in lysosomes of kidney cells by electron energy loss spectroscopy, Acta Histochem., 90 (1991) 65-73.
23. Lovell, M.A., Ehmann, W.D. and Markesbery, W.R., Quantification in laser microprobe mass spectrometry (LMMS), J. Trace Microprobe Tech., 10 (1992) 109-124.
24. Lovell, M.A., Ehmann, W.D. and Markesbery, W.R., Laser microprobe analysis of brain aluminum in Alzheimer's disease, Ann. Neurol, 33 (1992) 36-42.
25. Mantyh, P.W., Ghilardi, J.R., Rogers, S., DeMaster, E, Allen, C.J., Stimson, E.R. and Maggio, J.E., Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of β-amyloid peptide, J. Neurochem., 61 (1993) 1171-1174.
26. Mattson, M.P., Dou, P.M. and Kater, S.B., Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons, J. Neurosci., 8 (1988) 2087-2100.
27. Mattson, M.P., Wang, H. and Michaelis, E.K., Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons, Brain Res., 565 (1991) 94-108.
28. Mattson, M.P., Lovell, M.A., Ehmann, W.D. and Markesbery, W.R., Comparison of the effects of elevated intraneuronal aluminum and calcium levels on neuronal survival and tau immunoreactivity, Brain Res., 602 (1993) 21-31.
29. Mundy, W.R., Freudenrich, T.M., Kodavanti, P.R., Shafer, T.J. and Ward, T.R., Aluminum potentiates toxicant-induced calcium accumulation and reactive oxygen species formation in neuronal cell culture, Toxicologist, 15 (1995) 258-259.
30. Ohtawa, M., Seko, M. and Takayama, F., Effect of aluminum ingestion on lipid peroxidation in rats, Chem. Pharm. Bull., 31 (1983) 1415-1418.
31. 2+-induced lipid peroxidation in phosphatidylcholine liposomes by aluminum ions at physiological pH, Biochim. Biophys. Acta, 1170 (1993) 182-188.
32. Oteiza, P.I., A mechanism for the stimulatory effect of aluminum on iron-induced lipid peroxidation, Arch. Biochem. Biophys., 308 (1994) 374-379.
33. Perl, D.P. and Brody, A.R., Alzheimer's disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons, Science, 208 (1980) 297-299.
34. Perl, D.P., Gajdusek, C.D., Garrruto, R.M., Yanagihara, R.T. and Gibbs, C.J., Jr., Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia, Science, 217 (1982) 1053-1055.
35. Reed, P.W. and Lardy, H.A., A23187: A divalent cation ionophore, J. Biol. Chem., 247 (1972) 6970-6977.
36. Rosen, D.R., Siddique, T. Patterson, D., Figlewicz, D.A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J.P. and Deng, H.X., Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis, Nature, 362 (1992) 58-62.
37. Thompson, C.M., Markesbery, W.R., Ehmann, W.D., Mao, Y.X. and Vance, D.E., Regional brain trace-element studies in Alzheimer's disease, Neurotoxicology, 9 (1988) 1-8.
38. Thorne, B.M., Donohoe, T., Lin, K.N., Lyon, S., Mediros, D.M. and Weaver, M.L., Aluminum ingestion and behavior in the Long-Evans rat, Physiol. Behav., 36 (1986) 63-67.
39. Ward, N.I. and Mason, J.A., Neuron activation analysis techniques for identifying elemental status in Alzheimer's disease, J. Radioanal. Nucl. Chem., 113 (1987) 515-526.
40. Xie, C.X. and Yokel, R.A., Aluminum facilitation of iron-mediated lipid peroxidation is dependent on the substrate, pH, and aluminum and iron concentrations, Arch. Biochem. Biophys. , 327 (1996) 222-226.
41. Xie, C.X., St. Pyrek, J., Porter, W.H. and Yokel, R.A., Hydroxyl radical generation in rat brain is initiated by iron but not aluminum, as determined by microdialysis with salicylate trapping and GC-MS analysis, Neurotoxicology, 16 (1995) 489-496.
42. Xie, X., Yokel, R.A. and Markesbery, W.R., Application of electron energy loss spectroscopy and electron spectroscopic imaging to aluminum determination in biological tissue, Biol. Trace Elem. Res., 40 (1994) 39-48.
43. Yasui, M, Yase, Y., Ota, K., Mukoyama, M. and Adachi, K., High aluminum deposition in the central nervous system of patients with amyotrophic lateral sclerosis from the Ku Peninsula, Japan: two case reports, Neurotoxicology, 12 (1991) 277-284.
44. Yokel, R.A., Aluminum produces age related behavioral toxicity in the rabbit, Neurotoxicol Teratol., 11 (1989) 237-242.
45. Zemlan, F.P., Thienhaus, O.J. and Bosmann, H.B., Superoxide dismutase activity in Alzheimer's disease. Possible mechanism for paired helical filament formation, Brain Res., 476 (1989) 160-162.