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Volumn 2, Issue 4, 1999, Pages 374-381

Initial and innate responses to viral infections - Pattern setting in immunity or disease

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; INTERFERON; INTERLEUKIN 12;

EID: 0033178448     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(99)80066-6     Document Type: Review
Times cited : (216)

References (76)
  • 1
    • 0031050034 scopus 로고    scopus 로고
    • Innate immunity: Impact on the adaptive immune response
    • Medzhitov R, Janeway CA Jr: Innate immunity: Impact on the adaptive immune response. Curr Opin Immunol 1997, 9:4-9.
    • (1997) Curr Opin Immunol , vol.9 , pp. 4-9
    • Medzhitov, R.1    Janeway C.A., Jr.2
  • 2
    • 0032191163 scopus 로고    scopus 로고
    • Innate immune recognition and control of adaptive immune responses
    • Medzhitov R, Janeway CA Jr: Innate immune recognition and control of adaptive immune responses. Seminars Immunol 1998, 10:351-353. A brief overview of host germ-line receptor recognition of pattern structures found only on microorganisms, and the consequences of this recognition for activation of adaptive immune responses.
    • (1998) Seminars Immunol , vol.10 , pp. 351-353
    • Medzhitov, R.1    Janeway C.A., Jr.2
  • 3
    • 0032191176 scopus 로고    scopus 로고
    • Role of early cytokines, including alpha and beta interferons (IFNα/β), in innate and adaptive immune responses to viral infections
    • Biron CA: Role of early cytokines, including alpha and beta interferons (IFNα/β), in innate and adaptive immune responses to viral infections. Seminars Immunol 1998, 10:383-390. A brief review of known interferon-α/β anti-viral and immunoregulatory effects.
    • (1998) Seminars Immunol , vol.10 , pp. 383-390
    • Biron, C.A.1
  • 4
    • 0003049533 scopus 로고    scopus 로고
    • Immunity to viruses
    • Edited by Paul WE. Philadelphia: Lippincott-Raven
    • Ahmed R, Biron CA: Immunity to viruses. In Fundamental Immunology, Edn 4. Edited by Paul WE. Philadelphia: Lippincott-Raven; 1998:1295-1334. A thorough chapter on viral infections and the immune responses to them. Details on different types of viruses and host/pathogen interactions are presented.
    • (1998) Fundamental Immunology, Edn 4 , pp. 1295-1334
    • Ahmed, R.1    Biron, C.A.2
  • 5
    • 0033009888 scopus 로고    scopus 로고
    • Natural killer cells in antiviral defense: Function and regulation by innate cytokines
    • Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP: Natural killer cells in antiviral defense: Function and regulation by innate cytokines. Annu Rev Immunol 1999, 17:189-220. A comprehensive review of natural killer cell responses and functions during viral infections.
    • (1999) Annu Rev Immunol , vol.17 , pp. 189-220
    • Biron, C.A.1    Nguyen, K.B.2    Pien, G.C.3    Cousens, L.P.4    Salazar-Mather, T.P.5
  • 6
    • 0030745310 scopus 로고    scopus 로고
    • Molecules and mechanisms operating in septic shock: Lessons from knockout mice
    • Gutierrez-Ramos JC, Bluethmann H: Molecules and mechanisms operating in septic shock: Lessons from knockout mice. Immunol Today 1997, 18:329-334.
    • (1997) Immunol Today , vol.18 , pp. 329-334
    • Gutierrez-Ramos, J.C.1    Bluethmann, H.2
  • 7
    • 0028957492 scopus 로고
    • Mechanism of interleukin 12-mediated toxicities during experimental viral infections: Role of tumor necrosis factor and glucocorticoids
    • Orange JS, Salazar-Mather TP, Opal SM, Spencer RL, Miller AH, McEwen BS, Biron CA: Mechanism of interleukin 12-mediated toxicities during experimental viral infections: Role of tumor necrosis factor and glucocorticoids. J Exp Med 1995, 181:901-914.
    • (1995) J Exp Med , vol.181 , pp. 901-914
    • Orange, J.S.1    Salazar-Mather, T.P.2    Opal, S.M.3    Spencer, R.L.4    Miller, A.H.5    McEwen, B.S.6    Biron, C.A.7
  • 8
    • 0033137047 scopus 로고    scopus 로고
    • Synergism for cytokine-mediated disease during concurrent endotoxin and viral challenges: Roles for natural killer and T cell IFN-γ production
    • Nguyen KB, Biron CA: Synergism for cytokine-mediated disease during concurrent endotoxin and viral challenges: Roles for natural killer and T cell IFN-γ production. J Immunol 1999, 162:5238-5246. This paper presents studies of endogenous cytokine responses to lipopolysaccharide (LPS) in uninfected and virus-infected mice. Synergistic effects between LPS and endogenous lymphocytic choriomeningitis virus (LCMV) infections for expression of interferon-γ and induction of disease are characterized.
    • (1999) J Immunol , vol.162 , pp. 5238-5246
    • Nguyen, K.B.1    Biron, C.A.2
  • 9
    • 0000188185 scopus 로고    scopus 로고
    • Interferons and other cytokines
    • Edited by Fields BN, Knipe DM, Howley PM. New York: Lippincott-Raven
    • Vilcek J, Sen GC: Interferons and other cytokines. In Fundamental Virology, Edn 3. Edited by Fields BN, Knipe DM, Howley PM. New York: Lippincott-Raven; 1996:341-365.
    • (1996) Fundamental Virology, Edn 3 , pp. 341-365
    • Vilcek, J.1    Sen, G.C.2
  • 10
    • 0028332026 scopus 로고
    • Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B
    • Kumar A, Haque J, Lacoste J, Hiscott J, Williams BR: Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. Proc Natl Acad Sci USA 1994, 91:6288-6292.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6288-6292
    • Kumar, A.1    Haque, J.2    Lacoste, J.3    Hiscott, J.4    Williams, B.R.5
  • 11
    • 0024516201 scopus 로고
    • The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction
    • Lenardo MJ, Fan CM, Maniatis T, Baltimore D: The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 1989, 57:287-294.
    • (1989) Cell , vol.57 , pp. 287-294
    • Lenardo, M.J.1    Fan, C.M.2    Maniatis, T.3    Baltimore, D.4
  • 12
    • 0033111772 scopus 로고    scopus 로고
    • NFkappaB activation is required for interferon regulatory factor-1-mediated interferon beta induction
    • Kirchhoff S, Wilhelm D, Angel P, Hauser H: NFkappaB activation is required for interferon regulatory factor-1-mediated interferon beta induction. Eur J Biochem 1999, 261:546-554.
    • (1999) Eur J Biochem , vol.261 , pp. 546-554
    • Kirchhoff, S.1    Wilhelm, D.2    Angel, P.3    Hauser, H.4
  • 13
    • 0032015647 scopus 로고    scopus 로고
    • Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
    • Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, Maniatis T: Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell 1998, 1:507-518. The authors characterize a pathway for activation of Interferon (IFN) during viral infections. Specifically, an identified virus-activated factor (VAV) is shown to contain IRF-3 and IRF-7 and to be recruited to the IFN-β promoter.
    • (1998) Mol Cell , vol.1 , pp. 507-518
    • Wathelet, M.G.1    Lin, C.H.2    Parekh, B.S.3    Ronco, L.V.4    Howley, P.M.5    Maniatis, T.6
  • 14
    • 0032549658 scopus 로고    scopus 로고
    • Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene
    • Sato M, Tanaka N, Hata N, Oda E, Taniguchi T: Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene. FEBS Lett 1998, 425:112-116. The role of IRF-3 in induced activation of Interferon (IFN)-β after viral infection of cells is examined.
    • (1998) FEBS Lett , vol.425 , pp. 112-116
    • Sato, M.1    Tanaka, N.2    Hata, N.3    Oda, E.4    Taniguchi, T.5
  • 15
    • 0032579369 scopus 로고    scopus 로고
    • Regulation of type 1 interferon gene expression by interferon regulatory factor-3
    • Schafer SL, Lin R, Moore PA, Hiscott J, Pitha PM: Regulation of type 1 interferon gene expression by interferon regulatory factor-3. J Biol Chem 1998, 273:2714-2720. This paper biochemically characterizes the role for IRF-3 in activation of Interferon (IFN)-α4 and IFN-β genes. Results presented indicate that IRF-3 does not work alone, but can cooperate with other factors to stimulate expression of the IFN genes in particular cell types
    • (1998) J Biol Chem , vol.273 , pp. 2714-2720
    • Schafer, S.L.1    Lin, R.2    Moore, P.A.3    Hiscott, J.4    Pitha, P.M.5
  • 16
    • 0032544059 scopus 로고    scopus 로고
    • Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3
    • Juang Y, Lowther W, Kellum M, Au WC, Lin R, Hiscott J, Pitha PM: Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3. Proc Natl Acad Sci USA 1998, 95:9837-9842. Further characterization of the role for IRF-3 in interferon (IFN) expression. Data are presented indicating that anti-viral activity of IRF-3 results primarily from IFN induction in particular cells.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9837-9842
    • Juang, Y.1    Lowther, W.2    Kellum, M.3    Au, W.C.4    Lin, R.5    Hiscott, J.6    Pitha, P.M.7
  • 17
    • 0032538891 scopus 로고    scopus 로고
    • Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
    • Marie I, Durbin JE, Levy DE: Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J 1998, 17:6660-6669. These elegant studies dissect the steps in induction of particular interferon (IFN)-α/β genes after virus challenge of cells. An immediate early response of IFN-α4 followed by an IFN-α/β-receptor- and IRF-7-dependent induction of other IFN-α genes is characterized.
    • (1998) EMBO J , vol.17 , pp. 6660-6669
    • Marie, I.1    Durbin, J.E.2    Levy, D.E.3
  • 18
    • 0022398563 scopus 로고
    • Inhibition of herpes simplex virus type-1 induced interferon synthesis by monoclonal antibodies against viral glycoprotein D and by lysosomotropic drugs
    • Lebon P: Inhibition of herpes simplex virus type-1 induced interferon synthesis by monoclonal antibodies against viral glycoprotein D and by lysosomotropic drugs. J Gen Virol 1985, 66:2781-2786.
    • (1985) J Gen Virol , vol.66 , pp. 2781-2786
    • Lebon, P.1
  • 21
    • 0026556987 scopus 로고
    • Synthetic oligonucleotides with particular base sequences from the cDNA encoding proteins of Mycobacterium bovis BCG induce interferons and activate natural killer cells
    • Tokunaga T, Yano O, Kuramoto E, Kimura Y, Yamamoto T, Kataoka T, Yamamoto A: Synthetic oligonucleotides with particular base sequences from the cDNA encoding proteins of Mycobacterium bovis BCG induce interferons and activate natural killer cells. Microbiol Immunol 1992, 36:55-66.
    • (1992) Microbiol Immunol , vol.36 , pp. 55-66
    • Tokunaga, T.1    Yano, O.2    Kuramoto, E.3    Kimura, Y.4    Yamamoto, T.5    Kataoka, T.6    Yamamoto, A.7
  • 22
    • 0030239828 scopus 로고    scopus 로고
    • Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
    • Ballas ZK, Rasmussen WL, Krieg AM: Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol 1996, 157:1840-1845.
    • (1996) J Immunol , vol.157 , pp. 1840-1845
    • Ballas, Z.K.1    Rasmussen, W.L.2    Krieg, A.M.3
  • 23
    • 0019956727 scopus 로고
    • Evidence for a protective role of interferon in resistance to murine cytomegalovirus and its control by non-H-2-linked genes
    • Grundy (Chalmer) JE, Trapman J, Allan JE, Shellam GR, Melief CJM: Evidence for a protective role of interferon in resistance to murine cytomegalovirus and its control by non-H-2-linked genes. Infect Immun 1982, 37:143-150.
    • (1982) Infect Immun , vol.37 , pp. 143-150
    • Grundy, J.E.1    Trapman, J.2    Allan, J.E.3    Shellam, G.R.4    Melief, C.J.M.5
  • 24
    • 0018149529 scopus 로고
    • Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction
    • Welsh RM: Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction. J Exp Med 1978, 148:163-181.
    • (1978) J Exp Med , vol.148 , pp. 163-181
    • Welsh, R.M.1
  • 26
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch RJ, Tobias PS: Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu Rev Immunol 1995, 13:437-457.
    • (1995) Annu Rev Immunol , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 28
    • 0033597252 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced tumor necrosis factor-alpha promoter activity is inhibitor of nuclear factor-kappaB kinase-dependent
    • Swantek JL, Christerson L, Cobb MH: Lipopolysaccharide-induced tumor necrosis factor-alpha promoter activity is inhibitor of nuclear factor-kappaB kinase-dependent J Biol Chem 1999, 274:11667-11671.
    • (1999) J Biol Chem , vol.274 , pp. 11667-11671
    • Swantek, J.L.1    Christerson, L.2    Cobb, M.H.3
  • 29
    • 0032997542 scopus 로고    scopus 로고
    • Recognition of Gram-negative bacteria and endotoxin by the innate immune system
    • Ulevitch RJ, Tobias PS: Recognition of Gram-negative bacteria and endotoxin by the innate immune system. Curr Opin Immunol 1999, 11:19-22. A review of the biochemical events required for recognition of and induction of innate responses by lipopolysaccharide.
    • (1999) Curr Opin Immunol , vol.11 , pp. 19-22
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 30
    • 0028987562 scopus 로고
    • Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice
    • Wysocka M, Kubin M, Vieira LQ, Ozmen L, Garotta G, Scott P, Trinchieri G: Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol 1995, 25:672-676.
    • (1995) Eur J Immunol , vol.25 , pp. 672-676
    • Wysocka, M.1    Kubin, M.2    Vieira, L.Q.3    Ozmen, L.4    Garotta, G.5    Scott, P.6    Trinchieri, G.7
  • 31
    • 0029099391 scopus 로고
    • Effects of IL-12 on immune responses to microbial infections: A key mediator in regulating disease outcome
    • Biron CA, Gazzinelli RT: Effects of IL-12 on immune responses to microbial infections: A key mediator in regulating disease outcome. Curr Opin Immunol 1995, 7:485-496.
    • (1995) Curr Opin Immunol , vol.7 , pp. 485-496
    • Biron, C.A.1    Gazzinelli, R.T.2
  • 32
    • 0029096181 scopus 로고
    • Requirement for natural killer (NK) cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interelukin 12 administration
    • Orange JS, Wang B, Terhorst C, Biron CA: Requirement for natural killer (NK) cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interelukin 12 administration. J Exp Med 1995, 182:1045-1056.
    • (1995) J Exp Med , vol.182 , pp. 1045-1056
    • Orange, J.S.1    Wang, B.2    Terhorst, C.3    Biron, C.A.4
  • 33
    • 0030060232 scopus 로고    scopus 로고
    • An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and anitviral defense
    • Orange JS, Biron CA: An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and anitviral defense. J Immunol 1996, 156:1138-1142.
    • (1996) J Immunol , vol.156 , pp. 1138-1142
    • Orange, J.S.1    Biron, C.A.2
  • 34
    • 0029929032 scopus 로고    scopus 로고
    • Characterization of early IL-12, IFN-α/β, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection
    • Orange JS, Biron CA: Characterization of early IL-12, IFN-α/β, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection. J Immunol 1996, 156:4746-4756.
    • (1996) J Immunol , vol.156 , pp. 4746-4756
    • Orange, J.S.1    Biron, C.A.2
  • 35
    • 0030047502 scopus 로고    scopus 로고
    • Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. Implications in immunopathogenesis and protection
    • Kanagat S, Thomas J, Gangappa S, Babu JS, Rouse BT: Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. Implications in immunopathogenesis and protection. J Immunol 1996, 156:1110-1116.
    • (1996) J Immunol , vol.156 , pp. 1110-1116
    • Kanagat, S.1    Thomas, J.2    Gangappa, S.3    Babu, J.S.4    Rouse, B.T.5
  • 36
    • 0029975556 scopus 로고    scopus 로고
    • HSV-1-mediated modulation of cytokine gene expression in a permissive cell line: Selective upregulation of IL-6 gene expression
    • Kanangat S, Babu JS, Knipe DM, Rouse BT: HSV-1-mediated modulation of cytokine gene expression in a permissive cell line: Selective upregulation of IL-6 gene expression. Virology 1996, 219:295-300.
    • (1996) Virology , vol.219 , pp. 295-300
    • Kanangat, S.1    Babu, J.S.2    Knipe, D.M.3    Rouse, B.T.4
  • 37
    • 0031713209 scopus 로고    scopus 로고
    • Herpes simplex virus replication-induced expression of chemokines and proinflammatory cytokines in the eye: Implications in herpetic stromal keratitis
    • Thomas J, Kanangat S, Rouse BT: Herpes simplex virus replication-induced expression of chemokines and proinflammatory cytokines in the eye: Implications in herpetic stromal keratitis. J Interferon Cytokine Res 1998, 18:681-690.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 681-690
    • Thomas, J.1    Kanangat, S.2    Rouse, B.T.3
  • 38
    • 0028811975 scopus 로고
    • The T cell independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections
    • Heise MT, Virgin HW: The T cell independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections. J Virol 1995, 69:904-909.
    • (1995) J Virol , vol.69 , pp. 904-909
    • Heise, M.T.1    Virgin, H.W.2
  • 39
    • 0030945995 scopus 로고    scopus 로고
    • Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection
    • Ruzek MC, Miller AH, Opal SM, Pearce BD, Biron CA: Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection. J Exp Med 1997, 185:1185-1192.
    • (1997) J Exp Med , vol.185 , pp. 1185-1192
    • Ruzek, M.C.1    Miller, A.H.2    Opal, S.M.3    Pearce, B.D.4    Biron, C.A.5
  • 40
    • 0033559528 scopus 로고    scopus 로고
    • Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection
    • Ruzek MC, Pearce BD, Miller AH, Biron CA: Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection. J Immunol 1999, 162:3527-3533. This study characterizes the importance of an induced glucocorticoid response for protection against cytokine-mediated disease. The results demonstrate that magnitudes of the endogenous initial/innate tumor necrosis factor-α (TNF-α), interleukin (IL)-6, IL-12 and interferon-γ (IFN-γ) cytokine responses are negatively regulated by glucocorticoids, and that these hormones act to protect the host from TNF-mediated lethality.
    • (1999) J Immunol , vol.162 , pp. 3527-3533
    • Ruzek, M.C.1    Pearce, B.D.2    Miller, A.H.3    Biron, C.A.4
  • 41
    • 0029311726 scopus 로고
    • Human cytomegalovirus induces IL-6 and TNF alpha from macrophages and microglial cells: Possible role in neurotoxicity
    • Pulliam L, Moore D, West DC: Human cytomegalovirus induces IL-6 and TNF alpha from macrophages and microglial cells: Possible role in neurotoxicity. J Neuroviral 1995, 1:219-227.
    • (1995) J Neuroviral , vol.1 , pp. 219-227
    • Pulliam, L.1    Moore, D.2    West, D.C.3
  • 42
    • 0031926095 scopus 로고    scopus 로고
    • Role of interleukin-12 in primary influenza virus infection
    • Monteiro JM, Harvey C, Trinchieri G: Role of interleukin-12 in primary influenza virus infection. J Virol 1998, 72:4825-4831. This paper reports on the induction and function of interleukin (IL)-12 for natural killer (NK) cell interferon-γ (IFN-γ) responses, and apparent IL-12-independent T cell IFN-γ responses during influenza virus infections.
    • (1998) J Virol , vol.72 , pp. 4825-4831
    • Monteiro, J.M.1    Harvey, C.2    Trinchieri, G.3
  • 43
    • 0030840464 scopus 로고    scopus 로고
    • STATS and gene regulation
    • Darnell JE Jr: STATS and gene regulation. Science 1997, 277:1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell J.E., Jr.1
  • 44
    • 0027488067 scopus 로고
    • Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase
    • Karupiah G, Xie QW, Buller RM, Nathan C, Duarte C, MacMicking JD: Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase. Science 1993, 261:1445-1448.
    • (1993) Science , vol.261 , pp. 1445-1448
    • Karupiah, G.1    Xie, Q.W.2    Buller, R.M.3    Nathan, C.4    Duarte, C.5    MacMicking, J.D.6
  • 46
    • 0029591307 scopus 로고
    • IL12 in acute viral infectious disease
    • Biron CA, Orange JS: IL12 in acute viral infectious disease. Res Immunol 1995, 146:590-600.
    • (1995) Res Immunol , vol.146 , pp. 590-600
    • Biron, C.A.1    Orange, J.S.2
  • 47
    • 0031017252 scopus 로고    scopus 로고
    • IFN-α/β inhibition of IL-12 and IFN-γ production in vitro and endogenously during viral infection
    • Cousens LP, Orange JS, Su HC, Biron CA: IFN-α/β inhibition of IL-12 and IFN-γ production in vitro and endogenously during viral infection. Proc Natl Acad Sci USA 1997, 94:634-639.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 634-639
    • Cousens, L.P.1    Orange, J.S.2    Su, H.C.3    Biron, C.A.4
  • 48
    • 0033583516 scopus 로고    scopus 로고
    • Two roads diverged: Interferon α/β- and interleukin 12-mediated pathways in promoting T cell interferon γ responses during viral infection
    • Cousens LP, Peterson R, Hsu S, Dorner A, Altman JD, Ahmed R, Biron CA: Two roads diverged: Interferon α/β- and interleukin 12-mediated pathways in promoting T cell interferon γ responses during viral infection. J Exp Med 1999, 189:1315-1327. The authors define the existence of two possible pathways for promoting T cell interferon (IFN)-γ responses during viral infections. Results identify a dominant pathway under the control of IFN-α/β, and reveal a second interleukin (IL)-12-dependent pathway in the absence of IFN-α/β-mediated effects.
    • (1999) J Exp Med , vol.189 , pp. 1315-1327
    • Cousens, L.P.1    Peterson, R.2    Hsu, S.3    Dorner, A.4    Altman, J.D.5    Ahmed, R.6    Biron, C.A.7
  • 49
    • 0031736765 scopus 로고    scopus 로고
    • Positive and negative regulation of interleukin-12 gene expression
    • Ma X, Riemann H, Gri G, Trinchieri G: Positive and negative regulation of interleukin-12 gene expression. Eur Cytokine Netw 1998, 9:54-64.
    • (1998) Eur Cytokine Netw , vol.9 , pp. 54-64
    • Ma, X.1    Riemann, H.2    Gri, G.3    Trinchieri, G.4
  • 52
    • 0031019163 scopus 로고    scopus 로고
    • Activation and function of natural killer cell responses during viral infections
    • Biron CA: Activation and function of natural killer cell responses during viral infections. Curr Opin Immunol 1997, 9:24-34.
    • (1997) Curr Opin Immunol , vol.9 , pp. 24-34
    • Biron, C.A.1
  • 53
    • 0029805028 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo
    • Duncan GS, Mittrucker H-W, Kagi D, Matsuyama T, Mak TW: The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo. J Exp Med 1996, 184:2043-2048.
    • (1996) J Exp Med , vol.184 , pp. 2043-2048
    • Duncan, G.S.1    Mittrucker, H.-W.2    Kagi, D.3    Matsuyama, T.4    Mak, T.W.5
  • 54
    • 0032076635 scopus 로고    scopus 로고
    • Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
    • Zhang X, Sun S, Hwang I, Tough DF, Sprent J: Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity 1998, 8:591-599. This paper reports the sensitivity of memory but not naive T cells for IL-15 driven proliferation.
    • (1998) Immunity , vol.8 , pp. 591-599
    • Zhang, X.1    Sun, S.2    Hwang, I.3    Tough, D.F.4    Sprent, J.5
  • 55
    • 0031725321 scopus 로고    scopus 로고
    • Natural killer cell differentiation: Insights from knockout and transgenic mouse models and in vitro systems
    • Williams NS, Klem J, Puzanov IJ, Sivakumar PV, Schatzle JD, Bennett M, Kumar V: Natural killer cell differentiation: Insights from knockout and transgenic mouse models and in vitro systems. Immunol Rev 1998, 165:47-61. A thoughtful review of known requirements for natural killer (NK) cell development as elucidated through studies in genetically mutated mice and in tissue culture.
    • (1998) Immunol Rev , vol.165 , pp. 47-61
    • Williams, N.S.1    Klem, J.2    Puzanov, I.J.3    Sivakumar, P.V.4    Schatzle, J.D.5    Bennett, M.6    Kumar, V.7
  • 56
    • 0033046593 scopus 로고    scopus 로고
    • The multifaceted regulation of interleukin 15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens
    • Waldmann TA, Tagaya Y: The multifaceted regulation of interleukin 15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu Rev Immunol 1999, 17:19-49. A comprehensive review of interleukin (IL)-15 and its role in natural killer (NK) cell development and function.
    • (1999) Annu Rev Immunol , vol.17 , pp. 19-49
    • Waldmann, T.A.1    Tagaya, Y.2
  • 57
    • 0032510062 scopus 로고    scopus 로고
    • Requirement for IRF-1 in the microenvironment supporting development of natural killer cells
    • Ogasawara K, Hida S, Azimi N, Tagaya Y, Sato T, Yokochi-Fukuda T, Waldmann TA, Taniguchi T, Taki S: Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 1998, 391:700-703. This paper characterizes mechanisms for the IRF-1 contribution to natural killer cell development as mediated through radiation-resistant bone-marrow microenvironment cells and secondary to effects on interleukin (IL)-15 expression.
    • (1998) Nature , vol.391 , pp. 700-703
    • Ogasawara, K.1    Hida, S.2    Azimi, N.3    Tagaya, Y.4    Sato, T.5    Yokochi-Fukuda, T.6    Waldmann, T.A.7    Taniguchi, T.8    Taki, S.9
  • 58
    • 0032536787 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+T) cells, natural killer cells, and intestinal intraepithelial T cells
    • Ohteki T, Yoshida H, Matsuyama T, Duncan GS, Mak TW, Ohashi PS: The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+T) cells, natural killer cells, and intestinal intraepithelial T cells. J Exp Med 1998, 187:967-972. Additional studies on IRF-1 requirements for maturation of several cell populations including classic natural killer cells are reported.
    • (1998) J Exp Med , vol.187 , pp. 967-972
    • Ohteki, T.1    Yoshida, H.2    Matsuyama, T.3    Duncan, G.S.4    Mak, T.W.5    Ohashi, P.S.6
  • 59
    • 0024315206 scopus 로고
    • Severe herpesvirus infections in an adolescent without natural killer cells
    • Biron CA, Byron KS, Sullivan JL: Severe herpesvirus infections in an adolescent without natural killer cells. New Eng J Med 1989, 320:1731-1735.
    • (1989) New Eng J Med , vol.320 , pp. 1731-1735
    • Biron, C.A.1    Byron, K.S.2    Sullivan, J.L.3
  • 60
    • 0031974018 scopus 로고    scopus 로고
    • Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways
    • Salazar-Mather TP, Orange JS, Biron CA: Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways. J Exp Med 1998, 187:1-14. A thorough study characterizing the trafficking of natural killer (NK) cells to mediate anti-viral defense in infected livers. Results identify requirements for local accumulation of NK cells and NK cell-interferon-γ production, and the role of a chemokine, MIP-1α, for directing this localization in optimal resistance to infection.
    • (1998) J Exp Med , vol.187 , pp. 1-14
    • Salazar-Mather, T.P.1    Orange, J.S.2    Biron, C.A.3
  • 61
    • 0031060376 scopus 로고    scopus 로고
    • Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells
    • Tay CH, Welsh RM: Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells. J Virol 1997, 71:267-275.
    • (1997) J Virol , vol.71 , pp. 267-275
    • Tay, C.H.1    Welsh, R.M.2
  • 63
    • 0030731410 scopus 로고    scopus 로고
    • Mechanisms for virus-induced liver disease: Tumor necrosis factor-mediated pathology independent of natural killer and T cells during murine cytomegalovirus infection
    • Orange JS, Salazar-Mather TP, Opal SM, Biron CA: Mechanisms for virus-induced liver disease: Tumor necrosis factor-mediated pathology independent of natural killer and T cells during murine cytomegalovirus infection. J Virol 1997, 71:9248-9258.
    • (1997) J Virol , vol.71 , pp. 9248-9258
    • Orange, J.S.1    Salazar-Mather, T.P.2    Opal, S.M.3    Biron, C.A.4
  • 64
    • 0028266819 scopus 로고
    • Effects of IL-12 on the response and susceptibility to experimental viral infections
    • Orange JS, Wolf SF, Biron CA: Effects of IL-12 on the response and susceptibility to experimental viral infections. J Immunol 1994, 152:1253-1264.
    • (1994) J Immunol , vol.152 , pp. 1253-1264
    • Orange, J.S.1    Wolf, S.F.2    Biron, C.A.3
  • 65
    • 0024586663 scopus 로고
    • The activation of IL-2 transcription in L3T4+ and Lyt-2+ lymphocytes during virus infection in vivo
    • Kasaian MT, Biron CA: The activation of IL-2 transcription in L3T4+ and Lyt-2+ lymphocytes during virus infection in vivo. J Immunol 1989, 142:1287-1292.
    • (1989) J Immunol , vol.142 , pp. 1287-1292
    • Kasaian, M.T.1    Biron, C.A.2
  • 66
    • 0028843720 scopus 로고
    • Endogenous IL-2 contributes to T cell expansion and IFN-γ production during lymphocytic choriomeningitis virus infection
    • Cousens LP, Orange JS, Biron CA: Endogenous IL-2 contributes to T cell expansion and IFN-γ production during lymphocytic choriomeningitis virus infection. J Immunol 1995, 155:5690-5699.
    • (1995) J Immunol , vol.155 , pp. 5690-5699
    • Cousens, L.P.1    Orange, J.S.2    Biron, C.A.3
  • 68
    • 0032522640 scopus 로고    scopus 로고
    • Mice lacking IL-12 develop polarized Th1 cells during viral infection
    • Schijns VECJ, Haagmans BL, Wierda CMH, Kruithof B, Heijnen IAFM, Alber G, Hornizek MC: Mice lacking IL-12 develop polarized Th1 cells during viral infection. J Immunol 1998, 160:3958-3964. This study demonstrates interleukin (IL)-12-independent T cell interferon-γ responses during mouse hepatitis virus infections of mice rendered IL-12-deficient as a result of genetic mutation.
    • (1998) J Immunol , vol.160 , pp. 3958-3964
    • Schijns, V.E.C.J.1    Haagmans, B.L.2    Wierda, C.M.H.3    Kruithof, B.4    Heijnen, I.A.F.M.5    Alber, G.6    Hornizek, M.C.7
  • 69
    • 0033556145 scopus 로고    scopus 로고
    • IL-12 is not required for induction of type 1 cytokine responses in viral infections
    • + T cell Th1-dependent antibody, responses during lymphocytic choriomeningitis virus (LCMV) or vesicular stomatitis virus (VSV) infections of mice rendered IL-12-deficient as a result of genetic mutation.
    • (1999) J Immunol , vol.162 , pp. 965-973
    • Oxenius, A.1    Karrer, U.2    Zinkernagel, R.M.3    Hengartner, H.4
  • 71
    • 0029089972 scopus 로고
    • Polyinosinic acid: Polycytidylic acid promotes T helper type 1-specific immune responses by stimulating macrophage production of interieron-α and interleukin-12
    • Manetti R, Annuziato F, Tomasevic L, Gianno V, Parronchi P, Romagnani S, Maggi E: Polyinosinic acid: Polycytidylic acid promotes T helper type 1-specific immune responses by stimulating macrophage production of interieron-α and interleukin-12. Eur J Immunol 1995, 25:2656-2660.
    • (1995) Eur J Immunol , vol.25 , pp. 2656-2660
    • Manetti, R.1    Annuziato, F.2    Tomasevic, L.3    Gianno, V.4    Parronchi, P.5    Romagnani, S.6    Maggi, E.7
  • 72
    • 0032526917 scopus 로고    scopus 로고
    • Influenza A virus induced IFN-α/β and IL-18 synergistically enhance IFN-γ gene expression in human T cells
    • Saraneva T, Matikainen S, Kurimoto M, Julkunen I: Influenza A virus induced IFN-α/β and IL-18 synergistically enhance IFN-γ gene expression in human T cells. J Immunol 1998, 160:6032-6038. Potent synergistic effects of Interferon (IFN)-α/β and interleukin (IL)-18 for enhancing human T cell IFN-γ expression in culture are reported. The studies indicate that the effects on IFN-γ expression are independent of IL-12.
    • (1998) J Immunol , vol.160 , pp. 6032-6038
    • Saraneva, T.1    Matikainen, S.2    Kurimoto, M.3    Julkunen, I.4
  • 73
    • 0029671118 scopus 로고    scopus 로고
    • Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-1 development
    • Wenner CA, Guler ML, Macatonia SE, O'Garra A, Murphy KM: Roles of IFN-γ and IFN-α in IL-12-induced T helper cell-1 development. J Immunol 1996, 156:1442-1447.
    • (1996) J Immunol , vol.156 , pp. 1442-1447
    • Wenner, C.A.1    Guler, M.L.2    Macatonia, S.E.3    O'Garra, A.4    Murphy, K.M.5
  • 74
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and type I interferon in vivo
    • Tough DF, Borrow P, Sprent J: Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 1996, 272:1947-1950.
    • (1996) Science , vol.272 , pp. 1947-1950
    • Tough, D.F.1    Borrow, P.2    Sprent, J.3
  • 75
    • 0032433054 scopus 로고    scopus 로고
    • Type 1 interferon-mediated stimulation of T cells by CpG DNA
    • Sun S, Zhang X, Tough DF, Sprent J: Type 1 interferon-mediated stimulation of T cells by CpG DNA. J Exp Med 1998, 188:2335-2342. Studies investigating the role for Interferon (IFN)-α/β in stimulation of T cell responses by CpG DNA are presented. Experimental results show that the activation marker, CD69, is induced under these conditions through a pathway dependent upon the IFN-α/βR.
    • (1998) J Exp Med , vol.188 , pp. 2335-2342
    • Sun, S.1    Zhang, X.2    Tough, D.F.3    Sprent, J.4
  • 76
    • 0033081259 scopus 로고    scopus 로고
    • Type 1 interferons keep activated T cells alive
    • Marrack P, Kappler J, Mitchell T: Type 1 interferons keep activated T cells alive. J Exp Med 1999, 189:521-530. This paper reports effects of Interferon (IFN)-α/β on prolonging T cell survival following stimulation.
    • (1999) J Exp Med , vol.189 , pp. 521-530
    • Marrack, P.1    Kappler, J.2    Mitchell, T.3


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