메뉴 건너뛰기




Volumn 165, Issue , 1998, Pages 47-61

Natural killer cell differentiation: Insights from knockout and transgenic mouse models and in vitro systems

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN RECEPTOR;

EID: 0031725321     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1998.tb01229.x     Document Type: Review
Times cited : (112)

References (131)
  • 2
    • 0030716243 scopus 로고    scopus 로고
    • - cells from multipotential murine bone marrow progenitors in a stroma-free culture: Definition of cytokine requirements and developmental intermediates
    • - cells from multipotential murine bone marrow progenitors in a stroma-free culture: definition of cytokine requirements and developmental intermediates. J Exp Med 1997;186:1609-1614.
    • (1997) J Exp Med , vol.186 , pp. 1609-1614
    • Williams, N.S.1
  • 3
    • 0026451087 scopus 로고
    • Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment
    • Georgopoulos K, Moore DD, Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science 1992;258:808-812.
    • (1992) Science , vol.258 , pp. 808-812
    • Georgopoulos, K.1    Moore, D.D.2    Derfler, B.3
  • 4
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang J-H, et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996;5:537-549.
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.-H.1
  • 5
    • 0030703546 scopus 로고    scopus 로고
    • Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage
    • Wu L, Nichogiannopoulou A, Shortman K, Georgopoulos K. Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage. Immunity 1997;7:483-492.
    • (1997) Immunity , vol.7 , pp. 483-492
    • Wu, L.1    Nichogiannopoulou, A.2    Shortman, K.3    Georgopoulos, K.4
  • 6
    • 0028001362 scopus 로고
    • The Ikaros gene is required for the development of all lymphoid lineages
    • Georgopoulos K, et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994;79:143-156.
    • (1994) Cell , vol.79 , pp. 143-156
    • Georgopoulos, K.1
  • 7
    • 0030933151 scopus 로고    scopus 로고
    • The role of the Ikaros gene in lymphocyte development and homeostasis
    • Georgopoulos K, Winandy S, Avitahl N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annu Rev Immunol 1997;15:155-176.
    • (1997) Annu Rev Immunol , vol.15 , pp. 155-176
    • Georgopoulos, K.1    Winandy, S.2    Avitahl, N.3
  • 8
    • 0028111420 scopus 로고
    • A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3ε gene
    • Wang B, et al. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3ε gene. Proc Natl Acad Sci USA 1994;91:9402-9406.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9402-9406
    • Wang, B.1
  • 10
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997;91:661-672.
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 11
    • 0028784287 scopus 로고
    • Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset
    • Galy A, Travis M, Cen D, Chen B. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 1995;3:459-473.
    • (1995) Immunity , vol.3 , pp. 459-473
    • Galy, A.1    Travis, M.2    Cen, D.3    Chen, B.4
  • 12
    • 0025065459 scopus 로고
    • Primary structure and functional expression of rat and human stem cell factor DNAs
    • Martin FH, et al. Primary structure and functional expression of rat and human stem cell factor DNAs. Cell 1990;63:203-211.
    • (1990) Cell , vol.63 , pp. 203-211
    • Martin, F.H.1
  • 13
    • 0025077796 scopus 로고
    • The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus
    • Huang E, et al. The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 1990;63:225-233.
    • (1990) Cell , vol.63 , pp. 225-233
    • Huang, E.1
  • 14
    • 0025013548 scopus 로고
    • Identification of a ligand for the c-kit proto-oncogene
    • Williams DE, et al. Identification of a ligand for the c-kit proto-oncogene. Cell 1990;63:167-174.
    • (1990) Cell , vol.63 , pp. 167-174
    • Williams, D.E.1
  • 15
    • 0027146421 scopus 로고
    • Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
    • Lyman SD, et al. Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells. Cell 1993;75:1157-1167.
    • (1993) Cell , vol.75 , pp. 1157-1167
    • Lyman, S.D.1
  • 16
    • 0028318788 scopus 로고
    • Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
    • Hannum C, et al. Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs. Nature 1994;368:643-648.
    • (1994) Nature , vol.368 , pp. 643-648
    • Hannum, C.1
  • 17
    • 0032519768 scopus 로고    scopus 로고
    • c-kit ligand and flt3 ligand: Stem/progenitor cell factors with overlapping yet distinct activities
    • Lyman SD, Jacobsen SEW c-kit ligand and flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities. Blood 1998;91:1101-1134.
    • (1998) Blood , vol.91 , pp. 1101-1134
    • Lyman, S.D.1    Jacobsen, S.E.W.2
  • 19
    • 0030614362 scopus 로고    scopus 로고
    • bright natural killer cell subsets: Characterization of distinct functional responses to interleukin-2 and the c-kit ligand
    • bright natural killer cell subsets: characterization of distinct functional responses to interleukin-2 and the c-kit ligand. Eur J Immunol 1997;27:354-360.
    • (1997) Eur J Immunol , vol.27 , pp. 354-360
    • Carson, W.E.1    Fehniger, T.A.2    Caligiuri, M.A.3
  • 20
    • 0028041311 scopus 로고
    • The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2
    • Carson WE, Haldar S, Baiocchi RA, Croce CM, Caligiuri MA. The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2. Proc Natl Acad Sci USA 1994;81:7553-7557.
    • (1994) Proc Natl Acad Sci USA , vol.81 , pp. 7553-7557
    • Carson, W.E.1    Haldar, S.2    Baiocchi, R.A.3    Croce, C.M.4    Caligiuri, M.A.5
  • 25
    • 0029850719 scopus 로고    scopus 로고
    • Role of IL-2, IL-7, and IL-15 in natural killer differentation from cord blood hematopoietic progenitor cells and from γc transduced severe combined immunodeficiency X1 bone marrow cells
    • Cavazzana-Calvo M, et al. Role of IL-2, IL-7, and IL-15 in natural killer differentation from cord blood hematopoietic progenitor cells and from γc transduced severe combined immunodeficiency X1 bone marrow cells. Blood 1996;88:3901-3909.
    • (1996) Blood , vol.88 , pp. 3901-3909
    • Cavazzana-Calvo, M.1
  • 26
    • 0025334596 scopus 로고
    • 41, and W
    • 41, and W. EMBO J 1990;9:1805-1813.
    • (1990) EMBO J , vol.9 , pp. 1805-1813
    • Nocka, K.1
  • 28
    • 0021809335 scopus 로고
    • Origin and differentiation of natural killer cells. I. characteristics of a transplantable NK cell precursor
    • Hackett J Jr, Bennett M, Kumar V. Origin and differentiation of natural killer cells. I. characteristics of a transplantable NK cell precursor. J Immunol 1985;134:3731-3738.
    • (1985) J Immunol , vol.134 , pp. 3731-3738
    • Hackett Jr., J.1    Bennett, M.2    Kumar, V.3
  • 30
    • 0029145627 scopus 로고
    • Expression of flt3 receptor and flt3-ligand in human leukemia-lymphoma cell lines
    • Meierhoff G, et al. Expression of flt3 receptor and flt3-ligand in human leukemia-lymphoma cell lines. Leukemia 1995;9:1368-1372.
    • (1995) Leukemia , vol.9 , pp. 1368-1372
    • Meierhoff, G.1
  • 31
    • 4243762402 scopus 로고    scopus 로고
    • + hematopoetic progenitor cells (HPCs) when combined with interleukin 15 (IL-15)
    • Abstract
    • + hematopoetic progenitor cells (HPCs) when combined with interleukin 15 (IL-15). Blood 1996;88:105b (Abstract).
    • (1996) Blood , vol.88
    • Yu, H.1    Carson, W.2    Caligiuri, M.3
  • 32
    • 0003237953 scopus 로고    scopus 로고
    • Targeted disruption of the flt3 ligand gene in mice affects multiple hematopoietic lineages, including natural killer cells, B lymphocytes, and dendritic cells
    • Abstract
    • McKenna HJ, et al. Targeted disruption of the flt3 ligand gene in mice affects multiple hematopoietic lineages, including natural killer cells, B lymphocytes, and dendritic cells. Blood 1996;88:474a (Abstract).
    • (1996) Blood , vol.88
    • McKenna, H.J.1
  • 33
    • 0029097145 scopus 로고
    • Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors
    • Mackarehtschian K, Hardin JD, Moore KA, Boast S, Goff SP, Lemischka IR. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 1995;3:147-161.
    • (1995) Immunity , vol.3 , pp. 147-161
    • Mackarehtschian, K.1    Hardin, J.D.2    Moore, K.A.3    Boast, S.4    Goff, S.P.5    Lemischka, I.R.6
  • 34
    • 14444284333 scopus 로고    scopus 로고
    • Antirumor activity and immunotherapeutic properties of flt3-ligand in a murine breast cancer model
    • Chen K, et al. Antirumor activity and immunotherapeutic properties of flt3-ligand in a murine breast cancer model. Cancer Res 1997;57:3511-3516.
    • (1997) Cancer Res , vol.57 , pp. 3511-3516
    • Chen, K.1
  • 36
    • 0024307414 scopus 로고
    • Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-β
    • Lee G, Namen AE, Gillis S, Ellingsworth LR, Kincade PW. Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-β. J Immunol 1989;142:3875-3883.
    • (1989) J Immunol , vol.142 , pp. 3875-3883
    • Lee, G.1    Namen, A.E.2    Gillis, S.3    Ellingsworth, L.R.4    Kincade, P.W.5
  • 37
    • 0024462361 scopus 로고
    • IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets
    • Murray R, Suda T, Wrighton N, Lee F, Zlotnik A. IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets. Int Immunol 1989;1:526-531.
    • (1989) Int Immunol , vol.1 , pp. 526-531
    • Murray, R.1    Suda, T.2    Wrighton, N.3    Lee, F.4    Zlotnik, A.5
  • 38
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • Von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SEG, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995;181:1519-1526.
    • (1995) J Exp Med , vol.181 , pp. 1519-1526
    • Von Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3    McNeil, T.4    Seg, B.5    Murray, R.6
  • 40
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994;180:1955-1960.
    • (1994) J Exp Med , vol.180 , pp. 1955-1960
    • Peschon, J.J.1
  • 41
    • 0030018826 scopus 로고    scopus 로고
    • + T cells, but not for natural killer cells
    • + T cells, but not for natural killer cells. J Exp Med 1996;184:289-293.
    • (1996) J Exp Med , vol.184 , pp. 289-293
    • He, Y.-W.1    Malek, T.2
  • 42
    • 0025190716 scopus 로고
    • Interleukin 2-induced proliferation of murine natural killer cells in vivo
    • Biron CA, Young HA, Kasaian MT. Interleukin 2-induced proliferation of murine natural killer cells in vivo. J Exp Med 1990;171:173-188.
    • (1990) J Exp Med , vol.171 , pp. 173-188
    • Biron, C.A.1    Young, H.A.2    Kasaian, M.T.3
  • 43
    • 0024415547 scopus 로고
    • Expansion of natural killer cells but not T cells in human interleukin 2/interleukin 2 receptor (Tac) transgenic mice
    • Ishida Y, et al. Expansion of natural killer cells but not T cells in human interleukin 2/interleukin 2 receptor (Tac) transgenic mice. J Exp Med 1989;170:1103-1115.
    • (1989) J Exp Med , vol.170 , pp. 1103-1115
    • Ishida, Y.1
  • 44
    • 0028302710 scopus 로고
    • Generation of human natural killer cells from immature progenitors does not require marrow stromal cells
    • Silva MRG, Hoffman R, Srour EF, Ascensao JL. Generation of human natural killer cells from immature progenitors does not require marrow stromal cells. Blood 1994;84:841-846.
    • (1994) Blood , vol.84 , pp. 841-846
    • Silva, M.R.G.1    Hoffman, R.2    Srour, E.F.3    Ascensao, J.L.4
  • 47
    • 0028878330 scopus 로고
    • Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain
    • DiSanto JP, Müller W, Guy-Grand D, Fischer A, Rajewsky K. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc Natl Acad Sci USA 1995;92:377-381.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 377-381
    • DiSanto, J.P.1    Müller, W.2    Guy-Grand, D.3    Fischer, A.4    Rajewsky, K.5
  • 48
    • 0028925778 scopus 로고
    • Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
    • Cao X, et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 1995;2:223-238.
    • (1995) Immunity , vol.2 , pp. 223-238
    • Cao, X.1
  • 49
    • 0027403374 scopus 로고
    • Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
    • Noguchi M, et al. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 1993;73:147-157.
    • (1993) Cell , vol.73 , pp. 147-157
    • Noguchi, M.1
  • 50
    • 0029550822 scopus 로고
    • Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
    • Park SY, et al. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 1995;3:771-782.
    • (1995) Immunity , vol.3 , pp. 771-782
    • Park, S.Y.1
  • 51
    • 0028840706 scopus 로고
    • Defective lymphoid development in mice lacking Jak3
    • Nosaka T, et al. Defective lymphoid development in mice lacking Jak3. Science 1995;270:800-802.
    • (1995) Science , vol.270 , pp. 800-802
    • Nosaka, T.1
  • 52
    • 0028799457 scopus 로고
    • Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
    • Thomis DC, Gurniak CB, Tivol E, Shirpe AH, Berg LJ. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 1995;270:794-797.
    • (1995) Science , vol.270 , pp. 794-797
    • Thomis, D.C.1    Gurniak, C.B.2    Tivol, E.3    Shirpe, A.H.4    Berg, L.J.5
  • 53
    • 0029924265 scopus 로고    scopus 로고
    • The molecular basis of X-linked severe combined immunodeficiency: Defective cytokine receptor signaling
    • Leonard WJ. The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling. Annu Rev Med 1996;47:229-239.
    • (1996) Annu Rev Med , vol.47 , pp. 229-239
    • Leonard, W.J.1
  • 54
    • 0029006450 scopus 로고
    • IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2
    • Giri JG, Anderson DM, Kumaki S, Park LS, Grabstein KH, Cosman D. IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2. J Leukoc Biol 1995;57:763-766.
    • (1995) J Leukoc Biol , vol.57 , pp. 763-766
    • Giri, J.G.1    Anderson, D.M.2    Kumaki, S.3    Park, L.S.4    Grabstein, K.H.5    Cosman, D.6
  • 55
    • 0028179054 scopus 로고
    • Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor
    • Grabstein KH, et al. Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor. Science 1994;264:965-968.
    • (1994) Science , vol.264 , pp. 965-968
    • Grabstein, K.H.1
  • 56
    • 0028221433 scopus 로고
    • Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15
    • Giri JG, et al. Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 1994;13:2822-2830.
    • (1994) EMBO J , vol.13 , pp. 2822-2830
    • Giri, J.G.1
  • 57
    • 0029099146 scopus 로고
    • Identification and cloning of a novel IL-15 binding protein that is structurally related to the α chain of the IL-2 receptor
    • Giri JG, et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the α chain of the IL-2 receptor. EMBO J 1995;14:3654-3663.
    • (1995) EMBO J , vol.14 , pp. 3654-3663
    • Giri, J.G.1
  • 58
    • 0029788297 scopus 로고    scopus 로고
    • Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells
    • Leclercq G, Debacker V, De Smedt M, Plum J. Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells. J Exp Med 1996;184:325-336.
    • (1996) J Exp Med , vol.184 , pp. 325-336
    • Leclercq, G.1    Debacker, V.2    De Smedt, M.3    Plum, J.4
  • 59
    • 0030588575 scopus 로고    scopus 로고
    • IL-15 can substitute for the marrow microenvironment in the differentiation of natural killer cells
    • Puzanov IJ, Bennett M, Kumar V. IL-15 can substitute for the marrow microenvironment in the differentiation of natural killer cells. J Immunol 1996;157:4282-4285.
    • (1996) J Immunol , vol.157 , pp. 4282-4285
    • Puzanov, I.J.1    Bennett, M.2    Kumar, V.3
  • 60
    • 0031051547 scopus 로고    scopus 로고
    • Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain
    • Suzuki H, Duncan GS, Takimoto H, Mak TW. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain. J Exp Med 1997;185:499-505.
    • (1997) J Exp Med , vol.185 , pp. 499-505
    • Suzuki, H.1    Duncan, G.S.2    Takimoto, H.3    Mak, T.W.4
  • 61
    • 0028356473 scopus 로고
    • Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation
    • Guy-Grand D, et al. Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation. J Exp Med 1994;180:673-679.
    • (1994) J Exp Med , vol.180 , pp. 673-679
    • Guy-Grand, D.1
  • 62
    • 0029805028 scopus 로고    scopus 로고
    • The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo
    • Duncan GS, Mittrücker H-W Kägi D, Matsuyama T, Mak TW. The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo. J Exp Med 1996;184:2043-2048.
    • (1996) J Exp Med , vol.184 , pp. 2043-2048
    • Duncan, G.S.1    Mittrücker, H.-W.2    Kägi, D.3    Matsuyama, T.4    Mak, T.W.5
  • 63
    • 0030741433 scopus 로고    scopus 로고
    • Multistage regulation of Th1-type immune responses by the transcription factor IRF-1
    • Taki S, et al. Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity 1997;6:673-679.
    • (1997) Immunity , vol.6 , pp. 673-679
    • Taki, S.1
  • 64
    • 0032510062 scopus 로고    scopus 로고
    • Requirement for IRF-1 in the microenvironment supporting development of natural killer cells
    • Ogasawara K, et al. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 1998;391:700-703.
    • (1998) Nature , vol.391 , pp. 700-703
    • Ogasawara, K.1
  • 65
    • 0029121546 scopus 로고
    • Natural T cells: Cells that co-express NKRP-1 and TCR
    • Bix M, Locksley RM. Natural T cells: cells that co-express NKRP-1 and TCR. J Immunol 1995;155:1020-1022.
    • (1995) J Immunol , vol.155 , pp. 1020-1022
    • Bix, M.1    Locksley, R.M.2
  • 66
    • 0026048130 scopus 로고
    • A novel monoclonal antibody agains murine IL-2 receptor β-chain. Characterization of receptor expression in normal lymphoid cells and El-4 cells
    • Tanaka T, et al. A novel monoclonal antibody agains murine IL-2 receptor β-chain. Characterization of receptor expression in normal lymphoid cells and El-4 cells. J Immunol 1991;147:2222-2230.
    • (1991) J Immunol , vol.147 , pp. 2222-2230
    • Tanaka, T.1
  • 68
    • 0026645233 scopus 로고
    • - single-positive thymocyte subpopulation that expresses a highly skewed T cell antigen receptor family
    • - single-positive thymocyte subpopulation that expresses a highly skewed T cell antigen receptor family. Proc Natl Acad Sci USA 1992;89:6506-6510.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6506-6510
    • Arase, H.1    Arase, N.2    Ogasawara, K.3    Good, R.A.4    Onoe, K.5
  • 69
    • 0028025074 scopus 로고
    • - T cells in mice and humans
    • - T cells in mice and humans. J Exp Med 1994;180:1097-1106.
    • (1994) J Exp Med , vol.180 , pp. 1097-1106
    • Lantz, O.1    Bendelac, A.2
  • 70
    • 0028177589 scopus 로고
    • + T cells promptly produced IL-4 in response to in vivo challenge with anti-CD3
    • + T cells promptly produced IL-4 in response to in vivo challenge with anti-CD3. J Exp Med 1994;179:1285-1295.
    • (1994) J Exp Med , vol.179 , pp. 1285-1295
    • Yoshimoto, T.1    Paul, W.E.2
  • 73
    • 0030791028 scopus 로고    scopus 로고
    • Distinct roles for signals relayed through the common cytokine receptor γ chain and interleukin 7 receptor α chain in natural T cell development
    • Boesteanu A, De Silva AD, Nakajima H, Leonard WJ, Peschon JJ, Joyce S. Distinct roles for signals relayed through the common cytokine receptor γ chain and interleukin 7 receptor α chain in natural T cell development. J Exp Med 1997;186:331-336.
    • (1997) J Exp Med , vol.186 , pp. 331-336
    • Boesteanu, A.1    De Silva, A.D.2    Nakajima, H.3    Leonard, W.J.4    Peschon, J.J.5    Joyce, S.6
  • 74
    • 0028301248 scopus 로고
    • - murine thymocytes positively selected by class I molecules
    • - murine thymocytes positively selected by class I molecules. J Exp Med 1994;180:653-661.
    • (1994) J Exp Med , vol.180 , pp. 653-661
    • Vicari, A.1
  • 75
    • 0030904401 scopus 로고    scopus 로고
    • Lineage relationships and differentiation of natural killer (NK) T cells: Intrathymic selection and interleukin (IL)-4 production in the absence of NKR-P1 and Ly49 molecules
    • Lantz O, Sharara LI, Tilloy F, Andersson A, DiSanto JP. Lineage relationships and differentiation of natural killer (NK) T cells: intrathymic selection and interleukin (IL)-4 production in the absence of NKR-P1 and Ly49 molecules. J Exp Med 1997;185:1395-1401.
    • (1997) J Exp Med , vol.185 , pp. 1395-1401
    • Lantz, O.1    Sharara, L.I.2    Tilloy, F.3    Andersson, A.4    Disanto, J.P.5
  • 77
    • 0018097891 scopus 로고
    • Spontaneous cell-mediated cytotoxicity in humans: Role of interferon and immunoglobulins
    • Trinchieri G, Santoli D, Koprowski H. Spontaneous cell-mediated cytotoxicity in humans: role of interferon and immunoglobulins. J Immunol 1978;120:1849-1855.
    • (1978) J Immunol , vol.120 , pp. 1849-1855
    • Trinchieri, G.1    Santoli, D.2    Koprowski, H.3
  • 78
    • 0017660362 scopus 로고
    • Natural cell-mediated cytotoxicity in mice against non-lymphoid tumor cells and normal cells
    • Nunn ME, Heberman RB, Holden HT. Natural cell-mediated cytotoxicity in mice against non-lymphoid tumor cells and normal cells. Int J Cancer 1977;20:381-387.
    • (1977) Int J Cancer , vol.20 , pp. 381-387
    • Nunn, M.E.1    Heberman, R.B.2    Holden, H.T.3
  • 79
    • 0025300414 scopus 로고
    • In search of the 'missing self': MHC molecules and NK cell recognition
    • Ljunggren HG, Kärre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today 1990;11:237-244.
    • (1990) Immunol Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Kärre, K.2
  • 80
    • 0029003984 scopus 로고
    • Cloning of Ig-superfamily members associated with HLA-C and HLA-B recognition by human NK cells
    • Colonna M, Samaridis J. Cloning of Ig-superfamily members associated with HLA-C and HLA-B recognition by human NK cells. Science 1995;268:405-408.
    • (1995) Science , vol.268 , pp. 405-408
    • Colonna, M.1    Samaridis, J.2
  • 81
    • 0029015726 scopus 로고
    • Molecular clones of the p58 natural killer cell receptor reveal Ig-related molecules with diversity in both the extra- and intracellular domains
    • Wagtmann N, et al. Molecular clones of the p58 natural killer cell receptor reveal Ig-related molecules with diversity in both the extra- and intracellular domains. Immunity 1995;2:439-449.
    • (1995) Immunity , vol.2 , pp. 439-449
    • Wagtmann, N.1
  • 83
    • 0024553653 scopus 로고
    • Molecular cloning and characterization of a novel murine T cell surface antigen, YE1/48
    • Chan P-Y, Takei F. Molecular cloning and characterization of a novel murine T cell surface antigen, YE1/48. J Immunol 1989;142:1727-1736.
    • (1989) J Immunol , vol.142 , pp. 1727-1736
    • Chan, P.-Y.1    Takei, F.2
  • 84
    • 0028283541 scopus 로고
    • Ly-49 multigene family expressed by IL-2-activated NK cells
    • Smith HR, Karlhofer RM, Yokoyama WM. Ly-49 multigene family expressed by IL-2-activated NK cells. J Immunol 1994;153:1068-1079.
    • (1994) J Immunol , vol.153 , pp. 1068-1079
    • Smith, H.R.1    Karlhofer, R.M.2    Yokoyama, W.M.3
  • 85
    • 0031057435 scopus 로고    scopus 로고
    • Signal transduction by human NK cell MHC-recognizing receptors
    • Binstadt BA, Brumbaugh KM, Leibson PJ. Signal transduction by human NK cell MHC-recognizing receptors. Immunol Rev 1997;155:197-203.
    • (1997) Immunol Rev , vol.155 , pp. 197-203
    • Binstadt, B.A.1    Brumbaugh, K.M.2    Leibson, P.J.3
  • 86
    • 0031046520 scopus 로고    scopus 로고
    • Divergent functions of lectin-like receptors on NK cells
    • Ryan JC, Seaman WM. Divergent functions of lectin-like receptors on NK cells. Immunol Rev 1997;155:79-89.
    • (1997) Immunol Rev , vol.155 , pp. 79-89
    • Ryan, J.C.1    Seaman, W.M.2
  • 87
    • 0031020638 scopus 로고    scopus 로고
    • Mouse Ly49A interrupts early signaling events in NK cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase
    • Nakamura MC, Niemi EC, Fisher MJ, Shultz LD, Seaman WE, Ryan JC. Mouse Ly49A interrupts early signaling events in NK cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J Exp Med 1997;185:673-684.
    • (1997) J Exp Med , vol.185 , pp. 673-684
    • Nakamura, M.C.1    Niemi, E.C.2    Fisher, M.J.3    Shultz, L.D.4    Seaman, W.E.5    Ryan, J.C.6
  • 88
    • 0030848994 scopus 로고    scopus 로고
    • Signal transduction during natural killer cell activation: Inside the mind of a killer
    • Leibson PJ. Signal transduction during natural killer cell activation: inside the mind of a killer. Immunity 1997;6:655-661.
    • (1997) Immunity , vol.6 , pp. 655-661
    • Leibson, P.J.1
  • 89
    • 0019955969 scopus 로고
    • Positive self regulation of cytotoxicity in human natural killer cells by production of interferon upon exposure to influenza and herpes viruses
    • Djeu JY, Stocks N, Zoon K, Stanton GJ, Timonen T, Herberman RB. Positive self regulation of cytotoxicity in human natural killer cells by production of interferon upon exposure to influenza and herpes viruses. J Exp Med 1982;156:1222-1234.
    • (1982) J Exp Med , vol.156 , pp. 1222-1234
    • Djeu, J.Y.1    Stocks, N.2    Zoon, K.3    Stanton, G.J.4    Timonen, T.5    Herberman, R.B.6
  • 90
    • 0020601412 scopus 로고
    • Interleukin 2 enhances natural killer cell activity through induction of γ interferon
    • Weigent DA, Stanton GJ, Johnson HM. Interleukin 2 enhances natural killer cell activity through induction of γ interferon. Infect Immun 1983;41:992-997.
    • (1983) Infect Immun , vol.41 , pp. 992-997
    • Weigent, D.A.1    Stanton, G.J.2    Johnson, H.M.3
  • 91
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflamatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinichieri G. Interleukin-12: a proinflamatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995;13:251-276.
    • (1995) Annu Rev Immunol , vol.13 , pp. 251-276
    • Trinichieri, G.1
  • 92
    • 0028845730 scopus 로고
    • Cloning of a new cytokine that induces IFN-γ production by T cells
    • Okamura H, et al. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 1995;378:88-91.
    • (1995) Nature , vol.378 , pp. 88-91
    • Okamura, H.1
  • 93
    • 15844367093 scopus 로고    scopus 로고
    • Cloning of the cDNA for human IFN-γ inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein
    • Ushio S, et al. Cloning of the cDNA for human IFN-γ inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol 1996;156:4274-4279.
    • (1996) J Immunol , vol.156 , pp. 4274-4279
    • Ushio, S.1
  • 94
  • 95
    • 16044363695 scopus 로고    scopus 로고
    • IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses
    • Magram J, et al. IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses. Immunity 1996;4:471-481.
    • (1996) Immunity , vol.4 , pp. 471-481
    • Magram, J.1
  • 96
    • 18844481515 scopus 로고    scopus 로고
    • Defective NK cell activity and Th1 response in IL-18-deficient mice
    • Takeda K, et al. Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 1998;8:383-390.
    • (1998) Immunity , vol.8 , pp. 383-390
    • Takeda, K.1
  • 97
    • 0029116336 scopus 로고
    • Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
    • Bacon CM, et al. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc Natl Acad Sci USA 1995;92:7307-7311.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7307-7311
    • Bacon, C.M.1
  • 98
    • 0028943484 scopus 로고
    • Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
    • Jacobson NG, et al. Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med 1995;181:1755-1762.
    • (1995) J Exp Med , vol.181 , pp. 1755-1762
    • Jacobson, N.G.1
  • 99
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan MH, Sun Y-A, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996;382:174-177.
    • (1996) Nature , vol.382 , pp. 174-177
    • Kaplan, M.H.1    Sun, Y.-A.2    Hoey, T.3    Grusby, M.J.4
  • 100
    • 15844396183 scopus 로고    scopus 로고
    • Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
    • Thierfelder WE, et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 1996;382:171-173.
    • (1996) Nature , vol.382 , pp. 171-173
    • Thierfelder, W.E.1
  • 101
    • 0024360785 scopus 로고
    • Murine natural killer cells express functional Fcγ receptor II encoded by the FcγRα gene
    • Perussia B, et al. Murine natural killer cells express functional Fcγ receptor II encoded by the FcγRα gene. J Exp Med 1989;170:73-86.
    • (1989) J Exp Med , vol.170 , pp. 73-86
    • Perussia, B.1
  • 103
    • 0026681254 scopus 로고
    • A population of early fetal thymocytes expressing FcγRII/III contains precursors of T lymphocytes and natural killer cells
    • Rodewald HR, Moingeon P, Lucich JL, Dosiou C, Lopez P, Reinherz EL. A population of early fetal thymocytes expressing FcγRII/III contains precursors of T lymphocytes and natural killer cells. Cell 1992;69:139-150.
    • (1992) Cell , vol.69 , pp. 139-150
    • Rodewald, H.R.1    Moingeon, P.2    Lucich, J.L.3    Dosiou, C.4    Lopez, P.5    Reinherz, E.L.6
  • 104
    • 0028042424 scopus 로고
    • FcRγ chain deletion results in pleiotrophic effector cell defects
    • Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV. FcRγ chain deletion results in pleiotrophic effector cell defects. Cell 1994;76:519-529.
    • (1994) Cell , vol.76 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 106
    • 0029807865 scopus 로고    scopus 로고
    • + T and natural killer cell precursors in FcεRIγ transgenic mice
    • + T and natural killer cell precursors in FcεRIγ transgenic mice. J Exp Med 1996;184:1725-1735.
    • (1996) J Exp Med , vol.184 , pp. 1725-1735
    • Flamand, V.1
  • 107
    • 0024598415 scopus 로고
    • Effector and precursor phenotypes of lymphokine-activated killer cells in mice with severe combined immunodeficiency (scid) and athymic (nude) mice
    • Hasui M, et al. Effector and precursor phenotypes of lymphokine-activated killer cells in mice with severe combined immunodeficiency (scid) and athymic (nude) mice. Cell Immunol 1989;120:230-239.
    • (1989) Cell Immunol , vol.120 , pp. 230-239
    • Hasui, M.1
  • 108
    • 0026590084 scopus 로고
    • Thymic shared antigen-1. A novel thymocyte marker discriminating immature from mature thymocyte subsets
    • Godfrey DI, Masciantonio M, Tucek CL, Malin MA, Boyd RL, Hugo P. Thymic shared antigen-1. A novel thymocyte marker discriminating immature from mature thymocyte subsets. J Immunol 1992;148:2006-2011.
    • (1992) J Immunol , vol.148 , pp. 2006-2011
    • Godfrey, D.I.1    Masciantonio, M.2    Tucek, C.L.3    Malin, M.A.4    Boyd, R.L.5    Hugo, P.6
  • 109
    • 0028335847 scopus 로고
    • Thymic stem cells in mouse bone marrow
    • Antica M, Wu L, Shortman K, Scollay R. Thymic stem cells in mouse bone marrow. Blood 1994;84:111-117.
    • (1994) Blood , vol.84 , pp. 111-117
    • Antica, M.1    Wu, L.2    Shortman, K.3    Scollay, R.4
  • 110
    • 0029097045 scopus 로고
    • T-cell lineage commitment and cytokine responses of thymic progenitors
    • Moore TA, Zlotnik A. T-cell lineage commitment and cytokine responses of thymic progenitors. Blood 1995;86:1850-1860.
    • (1995) Blood , vol.86 , pp. 1850-1860
    • Moore, T.A.1    Zlotnik, A.2
  • 111
    • 0030054904 scopus 로고    scopus 로고
    • Flt3-ligand production by human bone marrow stromal cells
    • Lisovsky M, et al. Flt3-ligand production by human bone marrow stromal cells. Leukemia 1996;10:1012-1018.
    • (1996) Leukemia , vol.10 , pp. 1012-1018
    • Lisovsky, M.1
  • 112
    • 0028923125 scopus 로고
    • The flt3 hgand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: Synergistic interactions with interleukin (IL)-11, IL-12, and other hematopoietic growth factors
    • Jacobsen SE, Okkenhaug C, Mykleburst J, Veiby OP, Lyman SD. The flt3 hgand potently and directly stimulates the growth and expansion of primitive murine bone marrow progenitor cells in vitro: synergistic interactions with interleukin (IL)-11, IL-12, and other hematopoietic growth factors. J Exp Med 1995;181:1358-1363.
    • (1995) J Exp Med , vol.181 , pp. 1358-1363
    • Jacobsen, S.E.1    Okkenhaug, C.2    Mykleburst, J.3    Veiby, O.P.4    Lyman, S.D.5
  • 114
    • 17344367670 scopus 로고    scopus 로고
    • Natural killer cell differentiation: Receptor functions and repertoire
    • R. B. Herberman, W. H. Chambers, eds. Totowa (NJ): Humana Press (In press)
    • Williams NS, et al. Natural killer cell differentiation: receptor functions and repertoire. In: R. B. Herberman, W. H. Chambers, eds. NK cells and cancer: biology and therapy. Totowa (NJ): Humana Press (In press).
    • NK Cells and Cancer: Biology and Therapy
    • Williams, N.S.1
  • 115
    • 0027244760 scopus 로고
    • A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells
    • Garni-Wagner BA, Purohit A, Mathew PA, Bennett M, Kumar V. A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells. J Immunol 1993;151:60-70.
    • (1993) J Immunol , vol.151 , pp. 60-70
    • Garni-Wagner, B.A.1    Purohit, A.2    Mathew, P.A.3    Bennett, M.4    Kumar, V.5
  • 117
    • 0031039287 scopus 로고    scopus 로고
    • The Ly-49 family: Genes, proteins and recognition of class I MHC
    • Takei F, Brennan J, Mager DL. The Ly-49 family: genes, proteins and recognition of class I MHC. Immunol Rev 1997;155:67-77.
    • (1997) Immunol Rev , vol.155 , pp. 67-77
    • Takei, F.1    Brennan, J.2    Mager, D.L.3
  • 118
    • 0031038866 scopus 로고    scopus 로고
    • Host MHC class I gene control of NK-cell specificity in the mouse
    • Höglund P, et al. Host MHC class I gene control of NK-cell specificity in the mouse. Immunol Rev 1997;155:11-28.
    • (1997) Immunol Rev , vol.155 , pp. 11-28
    • Höglund, P.1
  • 119
    • 0031053169 scopus 로고    scopus 로고
    • Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors
    • Raulet DH, Held W, Correa I, Dorfman JR, Wu M-F, Corral L. Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors. Immunol Rev 1997;155:41-52.
    • (1997) Immunol Rev , vol.155 , pp. 41-52
    • Raulet, D.H.1    Held, W.2    Correa, I.3    Dorfman, J.R.4    Wu, M.-F.5    Corral, L.6
  • 120
    • 0031471613 scopus 로고    scopus 로고
    • - cells can distinguish the presence and absence of class I on target cells - Evidence for a Ly-49-independent negative signaling receptor
    • - cells can distinguish the presence and absence of class I on target cells - evidence for a Ly-49-independent negative signaling receptor. Eur J Immunol 1998;27:3100-3104.
    • (1998) Eur J Immunol , vol.27 , pp. 3100-3104
    • Sivakumar, P.V.1    Bennett, M.2    Kumar, V.3
  • 121
    • 0029151163 scopus 로고
    • Molecular characterization of human CD94: A type II membrane glycoprotein related to the C-type lectin superfamily
    • Chang C, Rodriguez A, Carretero M, López-Botet M, Phillips J, Lanier LL. Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Eur J Immunol 1995;25:2433-2437.
    • (1995) Eur J Immunol , vol.25 , pp. 2433-2437
    • Chang, C.1    Rodriguez, A.2    Carretero, M.3    López-Botet, M.4    Phillips, J.5    Lanier, L.L.6
  • 122
    • 0025754310 scopus 로고
    • DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells
    • Houchins JP, Yabe T, McSherry C, Bach FH. DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J Exp Med 1991;173:1017-1020.
    • (1991) J Exp Med , vol.173 , pp. 1017-1020
    • Houchins, J.P.1    Yabe, T.2    McSherry, C.3    Bach, F.H.4
  • 123
    • 0030470555 scopus 로고    scopus 로고
    • Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits
    • Lazetic S, Ching C, Houchins JP, Lanier LL, Phillips JH. Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J Immunol 1996;157:4741-4745.
    • (1996) J Immunol , vol.157 , pp. 4741-4745
    • Lazetic, S.1    Ching, C.2    Houchins, J.P.3    Lanier, L.L.4    Phillips, J.H.5
  • 124
    • 0031018766 scopus 로고    scopus 로고
    • NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor
    • Brooks AG, Posch PE, Scorzelli CJ, Borrego F, Coligan JE. NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J Exp Med 1997;185:795-800.
    • (1997) J Exp Med , vol.185 , pp. 795-800
    • Brooks, A.G.1    Posch, P.E.2    Scorzelli, C.J.3    Borrego, F.4    Coligan, J.E.5
  • 125
    • 0031053033 scopus 로고    scopus 로고
    • The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules
    • Carretero M, et al. The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules. Eur J Immunol 1997;27:563-567.
    • (1997) Eur J Immunol , vol.27 , pp. 563-567
    • Carretero, M.1
  • 127
    • 0031038920 scopus 로고    scopus 로고
    • Structure and function of the CD94 C-type lectin receptor complex involved in recognition of HLA class I molecules
    • López-Botet M, et al. Structure and function of the CD94 C-type lectin receptor complex involved in recognition of HLA class I molecules. Immunol Rev 1997;155:165-174.
    • (1997) Immunol Rev , vol.155 , pp. 165-174
    • López-Botet, M.1
  • 128
    • 0030217971 scopus 로고    scopus 로고
    • CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes
    • Phillips JH, Chang C, Mattson J, Gumperz JE, Parham P, Lanier LL. CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes. Immunity 1996;5:163-172.
    • (1996) Immunity , vol.5 , pp. 163-172
    • Phillips, J.H.1    Chang, C.2    Mattson, J.3    Gumperz, J.E.4    Parham, P.5    Lanier, L.L.6
  • 129
    • 0029801052 scopus 로고    scopus 로고
    • CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: Identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies
    • Sivori S, et al. CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies. Eur J Immunol 1996;26:2487-2492.
    • (1996) Eur J Immunol , vol.26 , pp. 2487-2492
    • Sivori, S.1
  • 130
    • 0032546001 scopus 로고    scopus 로고
    • HLA-E binds to natural killer cell receptors CD94/NKG2A, B, and C
    • Braud VM, et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B, and C. Nature 1998;391:795-799.
    • (1998) Nature , vol.391 , pp. 795-799
    • Braud, V.M.1
  • 131
    • 0032473478 scopus 로고    scopus 로고
    • Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
    • Borrego F, Ulbrecht M, Weiss EH, Coligan JE, Brooks AG. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J Exp Med 1998;187:813-818.
    • (1998) J Exp Med , vol.187 , pp. 813-818
    • Borrego, F.1    Ulbrecht, M.2    Weiss, E.H.3    Coligan, J.E.4    Brooks, A.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.