메뉴 건너뛰기




Volumn 35, Issue 3, 1999, Pages 181-195

Analysis of apoptosis by laser scanning cytometry

Author keywords

Annexin V; Bax; Bcl 2; Cell necrobiology; Chromatin condensation; DNA fragmentation; Mitochondria

Indexed keywords

3,3' DIHEXYLOXACARBOCYANINE; 7 AMINODACTINOMYCIN; DNA FRAGMENT; FLUORESCENT DYE; FLUOROCHROME; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; RHODAMINE 123;

EID: 0033105947     PISSN: 01964763     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0320(19990301)35:3<181::AID-CYTO1>3.0.CO;2-5     Document Type: Review
Times cited : (243)

References (120)
  • 2
    • 0031036984 scopus 로고    scopus 로고
    • Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis)
    • Darzynkiewicz Z, Juan G, Li X, Gorczyca W, Murakami T, Traganos F. Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry 1997;27:1-20.
    • (1997) Cytometry , vol.27 , pp. 1-20
    • Darzynkiewicz, Z.1    Juan, G.2    Li, X.3    Gorczyca, W.4    Murakami, T.5    Traganos, F.6
  • 3
    • 0028802897 scopus 로고
    • Nuclei acid dyes for detection of apoptosis in live cells
    • Frey T. Nuclei acid dyes for detection of apoptosis in live cells. Cytometry 1995;21:265-274.
    • (1995) Cytometry , vol.21 , pp. 265-274
    • Frey, T.1
  • 4
    • 0031825118 scopus 로고    scopus 로고
    • The study of apoptotic cells by flow cytometry
    • Ormerod MG. The study of apoptotic cells by flow cytometry. Leukemia 1998;12:1013-1025.
    • (1998) Leukemia , vol.12 , pp. 1013-1025
    • Ormerod, M.G.1
  • 5
    • 0028357173 scopus 로고
    • Rapid quantitation of apoptosis in pure and heterogenous cell populations using flow cytometry
    • Telford WG, King LE, Fraker PJ. Rapid quantitation of apoptosis in pure and heterogenous cell populations using flow cytometry. J Immunol Methods 1994;172:1-16.
    • (1994) J Immunol Methods , vol.172 , pp. 1-16
    • Telford, W.G.1    King, L.E.2    Fraker, P.J.3
  • 7
    • 0031034563 scopus 로고    scopus 로고
    • Controlling cell death
    • Golstein P. Controlling cell death. Science 1997;275:1081-1062.
    • (1997) Science , vol.275 , pp. 1081-11062
    • Golstein, P.1
  • 8
    • 0028149786 scopus 로고
    • Checkpoints of dueling dimers foil death wishes
    • Oltvai ZN, Korsmeyer SJ. Checkpoints of dueling dimers foil death wishes. Cell 1994;79:189-192.
    • (1994) Cell , vol.79 , pp. 189-192
    • Oltvai, Z.N.1    Korsmeyer, S.J.2
  • 10
    • 0032171223 scopus 로고    scopus 로고
    • Cell cycle effects and induction of apoptosis caused by infection of HL-60 cells with human granulocytic ehrlichiosis (HGE) pathogen measured by flow and laser scanning cytometry (LSC)
    • Bedner E, Burfeind P, Hsieh T-C, Wu JM, Augero-Rosenfeld M, Melamed MR, Horowitz HW, Wormser GP, Darzynkiewicz Z. Cell cycle effects and induction of apoptosis caused by infection of HL-60 cells with human granulocytic ehrlichiosis (HGE) pathogen measured by flow and laser scanning cytometry (LSC). Cytometry 1998;33:47-55.
    • (1998) Cytometry , vol.33 , pp. 47-55
    • Bedner, E.1    Burfeind, P.2    Hsieh, T.-C.3    Wu, J.M.4    Augero-Rosenfeld, M.5    Melamed, M.R.6    Horowitz, H.W.7    Wormser, G.P.8    Darzynkiewicz, Z.9
  • 11
    • 0028605481 scopus 로고
    • Bcl-2 in cancer, development and apoptosis
    • Hockenberry DM. Bcl-2 in cancer, development and apoptosis. J Cell Sci 1995;18:51-55.
    • (1995) J Cell Sci , vol.18 , pp. 51-55
    • Hockenberry, D.M.1
  • 12
    • 0030033049 scopus 로고    scopus 로고
    • Expression of the bcl-2 homologue mcl-1 correlates with survival of peripheral blood B lymphocytes
    • Lomo J, Smeland EB, Krajewski S, Reed JC, Blomhoff HK. Expression of the bcl-2 homologue mcl-1 correlates with survival of peripheral blood B lymphocytes. Cancer Res 1996;56:40-43.
    • (1996) Cancer Res , vol.56 , pp. 40-43
    • Lomo, J.1    Smeland, E.B.2    Krajewski, S.3    Reed, J.C.4    Blomhoff, H.K.5
  • 14
    • 0029944880 scopus 로고    scopus 로고
    • Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis
    • Castedo M, Hirsch T, Susi SA, Zamzani N, Marchetti P, Macho A, Kroemer G. Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. J Immunol 1996;157:512-521.
    • (1996) J Immunol , vol.157 , pp. 512-521
    • Castedo, M.1    Hirsch, T.2    Susi, S.A.3    Zamzani, N.4    Marchetti, P.5    Macho, A.6    Kroemer, G.7
  • 15
    • 0030057708 scopus 로고    scopus 로고
    • Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at a single organelle level
    • Cossarizza A, Ceccarelli D, Masini A. Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at a single organelle level. Exp Cell Res 1996;222:84-94.
    • (1996) Exp Cell Res , vol.222 , pp. 84-94
    • Cossarizza, A.1    Ceccarelli, D.2    Masini, A.3
  • 17
    • 0031018842 scopus 로고    scopus 로고
    • Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral lymphocytes during acute HIV syndrome
    • Cossarizza A, Mussini C, Mongiardo N, Borghi V, Sabbatini A, De Rienzo B, Franseschi C. Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral lymphocytes during acute HIV syndrome. AIDS 1997;11:19-26.
    • (1997) AIDS , vol.11 , pp. 19-26
    • Cossarizza, A.1    Mussini, C.2    Mongiardo, N.3    Borghi, V.4    Sabbatini, A.5    De Rienzo, B.6    Franseschi, C.7
  • 18
    • 0031871540 scopus 로고    scopus 로고
    • The mitochondion as an integrator/coordinator of cell death pathways
    • Kroemer G. The mitochondion as an integrator/coordinator of cell death pathways. Cell Death Differ 1998;5:547.
    • (1998) Cell Death Differ , vol.5 , pp. 547
    • Kroemer, G.1
  • 20
    • 0032580361 scopus 로고    scopus 로고
    • Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins
    • Zamzani N, Brenner C, Marzo I, Susin SA, Kroemer G. Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins. Oncogene 1998;16:2265-2282.
    • (1998) Oncogene , vol.16 , pp. 2265-2282
    • Zamzani, N.1    Brenner, C.2    Marzo, I.3    Susin, S.A.4    Kroemer, G.5
  • 21
    • 0032567877 scopus 로고    scopus 로고
    • The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition
    • Zamzani N, Marzo I, Susin SA, Brenner C, Larochette N, Marchetti P, Reed J, Kofler R, Kroemer G. The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition. Oncogene 1998;16:1055-1063.
    • (1998) Oncogene , vol.16 , pp. 1055-1063
    • Zamzani, N.1    Marzo, I.2    Susin, S.A.3    Brenner, C.4    Larochette, N.5    Marchetti, P.6    Reed, J.7    Kofler, R.8    Kroemer, G.9
  • 23
    • 0030015307 scopus 로고    scopus 로고
    • Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in Chinese hamster ovary cell cultures treated with cisplatin
    • Boersma AWM, Nooter K, Oostrum RG, Stoter G. Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in Chinese hamster ovary cell cultures treated with cisplatin. Cytometry 1996;24:125-130.
    • (1996) Cytometry , vol.24 , pp. 125-130
    • Boersma, A.W.M.1    Nooter, K.2    Oostrum, R.G.3    Stoter, G.4
  • 24
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok VA, Voelker DR, Cammpbell PA, Cohen JJ, Bratton DL, Henson PM. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 1992;148:2207-2216.
    • (1992) J Immunol , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Cammpbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 26
    • 0030054709 scopus 로고    scopus 로고
    • Generation of oxygen intermediates after treatment of blasts of acute myeloblastic leukemia with cytosine arabinoside: Role of bcl-2
    • Hedley DW, McCulloch EA. Generation of oxygen intermediates after treatment of blasts of acute myeloblastic leukemia with cytosine arabinoside: role of bcl-2. Leukemia 1996;10:1143-1149.
    • (1996) Leukemia , vol.10 , pp. 1143-1149
    • Hedley, D.W.1    McCulloch, E.A.2
  • 27
    • 0029036412 scopus 로고
    • Alterations of mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
    • Petit PX, LeCoeur H, Zorn E, Dauguet C, Mignotte B, Gougeon ML. Alterations of mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 1995;130: 157-165.
    • (1995) J Cell Biol , vol.130 , pp. 157-165
    • Petit, P.X.1    Lecoeur, H.2    Zorn, E.3    Dauguet, C.4    Mignotte, B.5    Gougeon, M.L.6
  • 28
    • 0028323164 scopus 로고
    • A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry
    • Gong J, Traganos F, Darzynkiewicz Z. A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal Biochem 1994;218:314-319.
    • (1994) Anal Biochem , vol.218 , pp. 314-319
    • Gong, J.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 29
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991;139:271-280.
    • (1991) J Immunol Methods , vol.139 , pp. 271-280
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 30
    • 0019889744 scopus 로고
    • In vivo DNA degradation in the thymocytes of gamma-irradiated or hydrocortisone-treated rats
    • Umansky SR, Korol' BR, Nelipovich PA. In vivo DNA degradation in the thymocytes of gamma-irradiated or hydrocortisone-treated rats. Biochim Biophys Acta 1981;655:281-290.
    • (1981) Biochim Biophys Acta , vol.655 , pp. 281-290
    • Umansky, S.R.1    Korol', B.R.2    Nelipovich, P.A.3
  • 31
    • 0028136653 scopus 로고
    • Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques
    • Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyka KV, Lassman H. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest 1994;71:219-225.
    • (1994) Lab Invest , vol.71 , pp. 219-225
    • Gold, R.1    Schmied, M.2    Giegerich, G.3    Breitschopf, H.4    Hartung, H.P.5    Toyka, K.V.6    Lassman, H.7
  • 33
    • 0001513802 scopus 로고
    • DNA strand breaks occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotydil transferase and nick translation assays and prevention by serine protease inhibitors
    • Gorczyca W, Bruno S, Darzynkiewicz R, Gong J, Darzynkiewicz Z. DNA strand breaks occurring during apoptosis: their early in situ detection by the terminal deoxynucleotydil transferase and nick translation assays and prevention by serine protease inhibitors. Int J Oncol 1992;1:639-648.
    • (1992) Int J Oncol , vol.1 , pp. 639-648
    • Gorczyca, W.1    Bruno, S.2    Darzynkiewicz, R.3    Gong, J.4    Darzynkiewicz, Z.5
  • 34
    • 0031041252 scopus 로고    scopus 로고
    • Laser scanning cytometry in pathology of solid tumors
    • Gorczyca W, Darzynkiewicz Z, Melamed MR. Laser scanning cytometry in pathology of solid tumors. Acta Cytol 1997;41:98-108.
    • (1997) Acta Cytol , vol.41 , pp. 98-108
    • Gorczyca, W.1    Darzynkiewicz, Z.2    Melamed, M.R.3
  • 35
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • Gorczyca W, Gong J, Darzynkiewicz Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res 1993;52:1945-1951.
    • (1993) Cancer Res , vol.52 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 36
    • 0030498295 scopus 로고    scopus 로고
    • Laser scanning cytometer (LSC) analysis of fraction of labeled mitoses (FLM)
    • Gorczyca W, Melamed MR, Darzynkiewicz Z. Laser scanning cytometer (LSC) analysis of fraction of labeled mitoses (FLM). Cell Prolif 1996;29:539-547.
    • (1996) Cell Prolif , vol.29 , pp. 539-547
    • Gorczyca, W.1    Melamed, M.R.2    Darzynkiewicz, Z.3
  • 37
    • 0027261147 scopus 로고
    • The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents
    • Gorczyca W, Gong J, Ardelt B, Traganos F, Darzynkiewicz Z. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 1993;53:3186-3192.
    • (1993) Cancer Res , vol.53 , pp. 3186-3192
    • Gorczyca, W.1    Gong, J.2    Ardelt, B.3    Traganos, F.4    Darzynkiewicz, Z.5
  • 38
    • 0029619116 scopus 로고
    • Labelling DNA strand breaks with BdrUTP. Detection of apoptosis and cell proliferation
    • Li X, Darzynkiewicz Z. Labelling DNA strand breaks with BdrUTP. Detection of apoptosis and cell proliferation. Cell Prolif 1995;28:571-579.
    • (1995) Cell Prolif , vol.28 , pp. 571-579
    • Li, X.1    Darzynkiewicz, Z.2
  • 40
    • 0030023087 scopus 로고    scopus 로고
    • Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color
    • Li X, Melamed MR, Darzynkiewicz Z. Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. Exp Cell Res 1996;222:28-37.
    • (1996) Exp Cell Res , vol.222 , pp. 28-37
    • Li, X.1    Melamed, M.R.2    Darzynkiewicz, Z.3
  • 41
    • 0029065342 scopus 로고
    • A single-step procedure for labeling DNA strand breaks with fluorescein-or BODIPY-conjugated deoxynucleotides: Detection of apoptosis and bromodeoxyuridine incorporation
    • Li X, Traganos F, Melamed MR, Darzynkiewicz Z. A single-step procedure for labeling DNA strand breaks with fluorescein-or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. Cytometry 1995;20:172-182.
    • (1995) Cytometry , vol.20 , pp. 172-182
    • Li, X.1    Traganos, F.2    Melamed, M.R.3    Darzynkiewicz, Z.4
  • 43
    • 0001877780 scopus 로고    scopus 로고
    • Measurements of cell death by flow cytometry
    • Cotter TG, Martin SJ, editors. London: Portland Press
    • Darzynkiewicz Z, Li X. Measurements of cell death by flow cytometry. In: Cotter TG, Martin SJ, editors. Techniques in apoptosis. A user's guide. London: Portland Press; 1996. p 71-106.
    • (1996) Techniques in Apoptosis. A User's Guide , pp. 71-106
    • Darzynkiewicz, Z.1    Li, X.2
  • 44
    • 0026655823 scopus 로고
    • Apoptosis in interleukin-3-dependent hemopoietic cells: Quantitation by two flow cytometric methods
    • Ormerod MG, Collins MKL, Rodriguez-Tarduchy G, Robertson D. Apoptosis in interleukin-3-dependent hemopoietic cells: quantitation by two flow cytometric methods. J Immunol Methods 1992;153: 57-66.
    • (1992) J Immunol Methods , vol.153 , pp. 57-66
    • Ormerod, M.G.1    Collins, M.K.L.2    Rodriguez-Tarduchy, G.3    Robertson, D.4
  • 45
    • 0027305202 scopus 로고
    • Radiation-induced apoptosis and necrosis in Molt-4 cells: A study of dose-effect relationship and their modification
    • Akagi Y, Ito K, Sawada S. Radiation-induced apoptosis and necrosis in Molt-4 cells: a study of dose-effect relationship and their modification. Int J Radiat Biol 1995;64:47-56.
    • (1995) Int J Radiat Biol , vol.64 , pp. 47-56
    • Akagi, Y.1    Ito, K.2    Sawada, S.3
  • 46
    • 0027853057 scopus 로고
    • Etoposide-induced cytotoxicity in two human T-cell leukemic lines: Delayed loss of membrane permeability rather than DNA fragmentation as an indicator of programmed cell death
    • Catchpoole DR, Stewart BW. Etoposide-induced cytotoxicity in two human T-cell leukemic lines: delayed loss of membrane permeability rather than DNA fragmentation as an indicator of programmed cell death. Cancer Res 1993;53:4287-4296.
    • (1993) Cancer Res , vol.53 , pp. 4287-4296
    • Catchpoole, D.R.1    Stewart, B.W.2
  • 47
    • 0026788002 scopus 로고
    • Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation
    • Cohen GM, Su X-M, Snowden RT, Dinsdale D, Skilleter DN. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem J 1992;286:331-334.
    • (1992) Biochem J , vol.286 , pp. 331-334
    • Cohen, G.M.1    Su, X.-M.2    Snowden, R.T.3    Dinsdale, D.4    Skilleter, D.N.5
  • 48
    • 0026555808 scopus 로고
    • Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis
    • Collins RJ, Harmon BV, Gobe GC, Kerr JFR. Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int J Radiat Biol 1992;61:451-453.
    • (1992) Int J Radiat Biol , vol.61 , pp. 451-453
    • Collins, R.J.1    Harmon, B.V.2    Gobe, G.C.3    Kerr, J.F.R.4
  • 49
    • 0027768576 scopus 로고
    • Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 7777 tissue: Apoptosis or necrosis?
    • Fukuda K, Kojiro M, Chiu J-F. Demonstration of extensive chromatin cleavage in transplanted Morris hepatoma 7777 tissue: apoptosis or necrosis? Am J Pathol 1993;142:935-946.
    • (1993) Am J Pathol , vol.142 , pp. 935-946
    • Fukuda, K.1    Kojiro, M.2    Chiu, J.-F.3
  • 50
    • 0028263376 scopus 로고
    • Cisplatin induced apoptosis in a human ovarian carcinoma cell line without a concomitant internucleosomal degradation of DNA
    • Ormerod MG, O'Neill CF, Robertson D, Harrap KR. Cisplatin induced apoptosis in a human ovarian carcinoma cell line without a concomitant internucleosomal degradation of DNA. Exp Cell Res 1994;211:231-237.
    • (1994) Exp Cell Res , vol.211 , pp. 231-237
    • Ormerod, M.G.1    O'Neill, C.F.2    Robertson, D.3    Harrap, K.R.4
  • 51
    • 0027419446 scopus 로고
    • Delayed internucleosomal DNA fragmentation in programmed cell death
    • Zakeri ZF, Quaglino D, Latham T, Lockshin RA. Delayed internucleosomal DNA fragmentation in programmed cell death. FASEB J 1993;7:470-478.
    • (1993) FASEB J , vol.7 , pp. 470-478
    • Zakeri, Z.F.1    Quaglino, D.2    Latham, T.3    Lockshin, R.A.4
  • 52
    • 0029986785 scopus 로고    scopus 로고
    • Supravital exposure to propidium iodide identifies apoptotic cells in the absence of nucleosomal DNA fragmentation
    • Zamai L, Falcieri E, Marhefka G, Vitale M. Supravital exposure to propidium iodide identifies apoptotic cells in the absence of nucleosomal DNA fragmentation. Cytometry 1996;23:303-311.
    • (1996) Cytometry , vol.23 , pp. 303-311
    • Zamai, L.1    Falcieri, E.2    Marhefka, G.3    Vitale, M.4
  • 54
    • 0027658225 scopus 로고
    • Role of proteolysis in apoptosis: Involvement of serine proteases in internucleosomal DNA fragmentation in immature lymphocytes
    • Weaver VM, Lach B, Walker PR, Sikorska M. Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature lymphocytes. Biochem Cell Biol 1993;71: 488-500.
    • (1993) Biochem Cell Biol , vol.71 , pp. 488-500
    • Weaver, V.M.1    Lach, B.2    Walker, P.R.3    Sikorska, M.4
  • 56
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Curie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Curie, A.R.3
  • 57
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995;146:3-16.
    • (1995) Am J Pathol , vol.146 , pp. 3-16
    • Majno, G.1    Joris, I.2
  • 59
    • 0025778621 scopus 로고
    • Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data
    • Kamentsky LA, Kamentsky LD. Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data. Cytometry 1991;12:381-387.
    • (1991) Cytometry , vol.12 , pp. 381-387
    • Kamentsky, L.A.1    Kamentsky, L.D.2
  • 60
    • 0030775970 scopus 로고    scopus 로고
    • Laser scanning cytometry distinguishes lymphocytes, monocytes and granulocytes by differences in their chromatin structure
    • Bedner E, Burfeind P, Gorczyca W, Melamed MR, Darzynkiewicz Z. Laser scanning cytometry distinguishes lymphocytes, monocytes and granulocytes by differences in their chromatin structure. Cytometry 1997;29:191-196.
    • (1997) Cytometry , vol.29 , pp. 191-196
    • Bedner, E.1    Burfeind, P.2    Gorczyca, W.3    Melamed, M.R.4    Darzynkiewicz, Z.5
  • 61
    • 0032171448 scopus 로고    scopus 로고
    • Enzyme kinetic reactions and fluorochrome uptake rates measured in individual cells by laser scanning cytometry (LSC)
    • Bedner E, Melamed MR, Darzynkiewicz Z. Enzyme kinetic reactions and fluorochrome uptake rates measured in individual cells by laser scanning cytometry (LSC). Cytometry 1998;33:1-9.
    • (1998) Cytometry , vol.33 , pp. 1-9
    • Bedner, E.1    Melamed, M.R.2    Darzynkiewicz, Z.3
  • 62
    • 0031929813 scopus 로고    scopus 로고
    • Simplified immunophenotypic analysis by laser scanning cytometry
    • Clatch RJ, Foreman JR, Walloch JL. Simplified immunophenotypic analysis by laser scanning cytometry. Cytometry 1998;34:3-16.
    • (1998) Cytometry , vol.34 , pp. 3-16
    • Clatch, R.J.1    Foreman, J.R.2    Walloch, J.L.3
  • 63
    • 0031929909 scopus 로고    scopus 로고
    • Five-color immunophenotyping plus DNA content analysis by laser scanning cytometry
    • Clatch RJ, Foreman JR. Five-color immunophenotyping plus DNA content analysis by laser scanning cytometry. Cytometry 1998;34:36-38.
    • (1998) Cytometry , vol.34 , pp. 36-38
    • Clatch, R.J.1    Foreman, J.R.2
  • 64
    • 0031048277 scopus 로고    scopus 로고
    • Multiparameter immunophenotypic analysis of line needle aspiration biopsies and other hematologic specimens by laser scanning cytometry
    • Clatch RJ, Walloch JL. Multiparameter immunophenotypic analysis of line needle aspiration biopsies and other hematologic specimens by laser scanning cytometry. Acta Cytol 1997;41:109-122.
    • (1997) Acta Cytol , vol.41 , pp. 109-122
    • Clatch, R.J.1    Walloch, J.L.2
  • 65
    • 0032213299 scopus 로고    scopus 로고
    • Activation of nuclear factor kappa B (NF?-B) assayed by laser scanning cytometry (LSC)
    • Deptala A, Bedner E, Gorczyca W, Darzynkiewicz Z. Activation of nuclear factor kappa B (NF?-B) assayed by laser scanning cytometry (LSC). Cytometry 1998;33:376-382.
    • (1998) Cytometry , vol.33 , pp. 376-382
    • Deptala, A.1    Bedner, E.2    Gorczyca, W.3    Darzynkiewicz, Z.4
  • 66
    • 0030765495 scopus 로고    scopus 로고
    • Laser scanning cytometry allows detection of cell death with morphological features of apoptosis in cells stained with PI
    • Furuya T, Kamada T, Murakami T, Kurose A, Sasaki K. Laser scanning cytometry allows detection of cell death with morphological features of apoptosis in cells stained with PI. Cytometry 1997;29:173-177.
    • (1997) Cytometry , vol.29 , pp. 173-177
    • Furuya, T.1    Kamada, T.2    Murakami, T.3    Kurose, A.4    Sasaki, K.5
  • 67
    • 0029996303 scopus 로고    scopus 로고
    • Resolution of mitotic cells using laser scanning cytometry
    • Luther E, Kamentsky LA. Resolution of mitotic cells using laser scanning cytometry. Cytometry 1996;23:272-278.
    • (1996) Cytometry , vol.23 , pp. 272-278
    • Luther, E.1    Kamentsky, L.A.2
  • 68
    • 0345407178 scopus 로고    scopus 로고
    • Analysis of apoptotic cells by flow-and laser scanning-cytometry
    • Reed JC, editor. San Diego: Academic Press; in press
    • Darzynkiewicz Z, Bedner E. Analysis of apoptotic cells by flow-and laser scanning-cytometry. In: Reed JC, editor. Methods in enzymology. Methods in apoptosis research. San Diego: Academic Press; in press.
    • Methods in Enzymology. Methods in Apoptosis Research
    • Darzynkiewicz, Z.1    Bedner, E.2
  • 71
    • 0026556554 scopus 로고
    • Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry
    • Schmid I, Krall WJ, Uittenbogaart GH, Braun J, Giorgi JV. Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry 1992;13:204-208.
    • (1992) Cytometry , vol.13 , pp. 204-208
    • Schmid, I.1    Krall, W.J.2    Uittenbogaart, G.H.3    Braun, J.4    Giorgi, J.V.5
  • 72
    • 0027979892 scopus 로고
    • Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry
    • Schmid I, Uttenbogaart CH, Giorgi JV. Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry. Cytometry 1994;15:12-20.
    • (1994) Cytometry , vol.15 , pp. 12-20
    • Schmid, I.1    Uttenbogaart, C.H.2    Giorgi, J.V.3
  • 73
    • 0007574262 scopus 로고
    • Localization of mitochondria in living cells with rhodamine 123
    • Johnson LV, Walsh ML, Chen LB. Localization of mitochondria in living cells with rhodamine 123. Proc Natl Acad Sci USA 1980;77:990-994.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 990-994
    • Johnson, L.V.1    Walsh, M.L.2    Chen, L.B.3
  • 80
    • 0031956807 scopus 로고    scopus 로고
    • Detection of HIV-RNA positive monocytes in peripheral blood of HIV-positive patients by simultaneous flow cytometric analysis of intracellular HIV RNA and cellular immunophenotype
    • Patterson BK, Mosiman VL, Cantarero L, Furtado M, Bhattacharya M, Goolsby C. Detection of HIV-RNA positive monocytes in peripheral blood of HIV-positive patients by simultaneous flow cytometric analysis of intracellular HIV RNA and cellular immunophenotype. Cytometry 1998;31:265-274.
    • (1998) Cytometry , vol.31 , pp. 265-274
    • Patterson, B.K.1    Mosiman, V.L.2    Cantarero, L.3    Furtado, M.4    Bhattacharya, M.5    Goolsby, C.6
  • 84
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997;275:1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 85
    • 0002127628 scopus 로고    scopus 로고
    • The Bcl-2 family of proteins and activation of the ICE-CES-3 family of proteases: A balancing act in apoptosis?
    • Kumar S. The Bcl-2 family of proteins and activation of the ICE-CES-3 family of proteases: a balancing act in apoptosis? Cell Death Differ 1997;4:2-4.
    • (1997) Cell Death Differ , vol.4 , pp. 2-4
    • Kumar, S.1
  • 86
    • 0002497394 scopus 로고    scopus 로고
    • Bcl-2 family proteins: Role in dysregulation of apoptosis and chemoresistance in cancer
    • Martin SJ, editor. Basel: Karger Landes Systems
    • Reed JC. Bcl-2 family proteins: role in dysregulation of apoptosis and chemoresistance in cancer. In: Martin SJ, editor. Apoptosis and Cancer. Basel: Karger Landes Systems; 1997. p 64-97.
    • (1997) Apoptosis and Cancer , pp. 64-97
    • Reed, J.C.1
  • 87
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC. Bcl-2 and the regulation of programmed cell death. J Cell Biol 1994;124:1-6.
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 88
    • 0029884711 scopus 로고    scopus 로고
    • Bcl-2 blocks loss of mitochondrial transmembrane potential while ICE inhibitors act at different step during inhibition of death induced by respiratory chain inhibitors
    • Shimizu S, Eguchi Y, Kamiike Y, Waguri W, Uchiyama Y, Matsuda H, Tsujimo Y. Bcl-2 blocks loss of mitochondrial transmembrane potential while ICE inhibitors act at different step during inhibition of death induced by respiratory chain inhibitors. Oncogene 1996;13: 21-30.
    • (1996) Oncogene , vol.13 , pp. 21-30
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, Y.3    Waguri, W.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimo, Y.7
  • 89
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-XL and Bcl-2 displaces bax and promotes cell death
    • Yang E, Zha J, Jockel J, Boise LH, Thompson SB, Krosmeyer SJ. Bad, a heterodimeric partner for Bcl-XL and Bcl-2 displaces bax and promotes cell death. Cell 1995;80:285-291.
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boise, L.H.4    Thompson, S.B.5    Krosmeyer, S.J.6
  • 90
  • 91
    • 0032568954 scopus 로고    scopus 로고
    • Apoptosis induction by caspase-8 is amplified through mitochondrial release of cytochrome c
    • Kuwana T, Smith JJ, Muzio M, Dixit V, Newmeyer DD, Kornbluth S. Apoptosis induction by caspase-8 is amplified through mitochondrial release of cytochrome c. J Biol Chem 1998;273:16589-1694.
    • (1998) J Biol Chem , vol.273 , pp. 16589-21694
    • Kuwana, T.1    Smith, J.J.2    Muzio, M.3    Dixit, V.4    Newmeyer, D.D.5    Kornbluth, S.6
  • 94
    • 0031034997 scopus 로고    scopus 로고
    • Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
    • Chinnaiyan AM, O'Rourke K, Lane BR, Dixit VM. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 1997;175:1122-1126.
    • (1997) Science , vol.175 , pp. 1122-1126
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Lane, B.R.3    Dixit, V.M.4
  • 97
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 1994;371:346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 98
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and ATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhavan D, Budihardijo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X. Cytochrome c and ATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhavan, D.2    Budihardijo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 99
    • 0031020227 scopus 로고    scopus 로고
    • Interaction and regulation of subcellular localization of CED-4 by CED-9
    • Wu D, Wallen H, Nunez G. Interaction and regulation of subcellular localization of CED-4 by CED-9. Science 1997;175:1126-1129.
    • (1997) Science , vol.175 , pp. 1126-1129
    • Wu, D.1    Wallen, H.2    Nunez, G.3
  • 100
    • 0030740251 scopus 로고    scopus 로고
    • CED-4 - The third horseman of apoptosis
    • Vaux DL. CED-4 - the third horseman of apoptosis. Cell 1997;90:389-390.
    • (1997) Cell , vol.90 , pp. 389-390
    • Vaux, D.L.1
  • 101
    • 0027535559 scopus 로고
    • Toward an understanding of the molecular mechanisms of physiological cell death
    • Vaux DL. Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA 1993;90:786-789.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 786-789
    • Vaux, D.L.1
  • 102
    • 0030889455 scopus 로고    scopus 로고
    • Detection of apoptosis in live cells by MitoTracker Red CMXRos and SYTO dye flow cytometry
    • Poot M, Gibson LL, Singer VL. Detection of apoptosis in live cells by MitoTracker( Red CMXRos and SYTO dye flow cytometry. Cytometry 1997;27:358-64.
    • (1997) Cytometry , vol.27 , pp. 358-364
    • Poot, M.1    Gibson, L.L.2    Singer, V.L.3
  • 103
    • 0013866506 scopus 로고
    • Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters
    • Rotman B, Papermaster BW. Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters. Proc Natl Acad Sci USA 1966;55:134-139.
    • (1966) Proc Natl Acad Sci USA , vol.55 , pp. 134-139
    • Rotman, B.1    Papermaster, B.W.2
  • 104
    • 0027513268 scopus 로고
    • Apoptosis
    • Cohen JJ. Apoptosis. Immunol Today 1993;14:126-130.
    • (1993) Immunol Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 105
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, A.3
  • 107
    • 0027163053 scopus 로고
    • Detection of DNA fragmentation in apoptosis: Application of in situ nick translation to cell culture systems and tissue sections
    • Gold R, Schmied M, Rothe G, Zischler H, Breitschopf H, Wekerle H, Lassman H. Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections. J Histochem Cytochem 1993;41:1023-1030.
    • (1993) J Histochem Cytochem , vol.41 , pp. 1023-1030
    • Gold, R.1    Schmied, M.2    Rothe, G.3    Zischler, H.4    Breitschopf, H.5    Wekerle, H.6    Lassman, H.7
  • 108
    • 0039205737 scopus 로고    scopus 로고
    • Methods for analysis of apoptosis by flow cytometry
    • Rose NR, de Macario EC, Folds JD, Lane HC, Nakamura R, editors. Washington, DC: ASM Press
    • Darzynkiewicz Z, Li X, Gong J, Traganos F. Methods for analysis of apoptosis by flow cytometry. In: Rose NR, de Macario EC, Folds JD, Lane HC, Nakamura R, editors. Manual of clinical laboratory immunology, fifth edition. Washington, DC: ASM Press; 1997. p 334-344.
    • (1997) Manual of Clinical Laboratory Immunology, Fifth Edition , pp. 334-344
    • Darzynkiewicz, Z.1    Li, X.2    Gong, J.3    Traganos, F.4
  • 109
    • 0028706970 scopus 로고
    • Assays of cell viability. Discrimination of cells dying by apoptosis
    • Darzynkiewicz Z, Li X, Gong J. Assays of cell viability. Discrimination of cells dying by apoptosis. Methods Cell Biol 1994;41:16-39.
    • (1994) Methods Cell Biol , vol.41 , pp. 16-39
    • Darzynkiewicz, Z.1    Li, X.2    Gong, J.3
  • 111
    • 0345379974 scopus 로고
    • Flow cytometry studies in HIV disease: Relevance to AIDS vaccine development
    • Giorgi JV, Janossy G. Flow cytometry studies in HIV disease: relevance to AIDS vaccine development. AIDS [Suppl] 1994;8:1-11.
    • (1994) AIDS [Suppl] , vol.8 , pp. 1-11
    • Giorgi, J.V.1    Janossy, G.2
  • 112
    • 0031923938 scopus 로고    scopus 로고
    • Novel approach for simultaneous evaluation of cell phenotype, and cell cycle using multiparameter flow cytometry
    • Douglas RS, Pletcher CH Jr, Nowell PC, Moore JS. Novel approach for simultaneous evaluation of cell phenotype, and cell cycle using multiparameter flow cytometry. Cytometry 1998;32:57-65.
    • (1998) Cytometry , vol.32 , pp. 57-65
    • Douglas, R.S.1    Pletcher C.H., Jr.2    Nowell, P.C.3    Moore, J.S.4
  • 113
  • 115
    • 0028047345 scopus 로고
    • Identification of granulocytotropic Ehrlichiae species as the etiologic agent of human disease
    • Chen SM, Dunler JS, Bakken JS, Walker DH. Identification of granulocytotropic Ehrlichiae species as the etiologic agent of human disease. J Clin Microbiol 1994;32:589-598.
    • (1994) J Clin Microbiol , vol.32 , pp. 589-598
    • Chen, S.M.1    Dunler, J.S.2    Bakken, J.S.3    Walker, D.H.4
  • 116
    • 0029079228 scopus 로고
    • Apoptosis in antitumor strategies: Modulation of cell cycle and differentiation
    • Darzynkiewicz Z. Apoptosis in antitumor strategies: modulation of cell cycle and differentiation. J Cell Biochem 1995;58:151-159.
    • (1995) J Cell Biochem , vol.58 , pp. 151-159
    • Darzynkiewicz, Z.1
  • 118
    • 0013673631 scopus 로고    scopus 로고
    • TNF-bascd strategies for manipulating apoptosis: Adjuncts to cancer therapy
    • Martin SJ, editor. Basel: Karger Landes Systems
    • Wong GHW, Wehar G, Kaspar RL. TNF-bascd strategies for manipulating apoptosis: Adjuncts to cancer therapy. In: Martin SJ, editor. Apoptosis and cancer. Basel: Karger Landes Systems; 1997. p 245-257.
    • (1997) Apoptosis and Cancer , pp. 245-257
    • Wong, G.H.W.1    Wehar, G.2    Kaspar, R.L.3
  • 120
    • 0032145154 scopus 로고    scopus 로고
    • Analysis and sorting of apoptotic cells from fine-needle aspirates of excised human primary breast carcinomas
    • Dowsett M, Detre S, Ormerod MG, Ellis PA, Mainwaring PN, Titley JC, Smith IE. Analysis and sorting of apoptotic cells from fine-needle aspirates of excised human primary breast carcinomas. Cytometry 1998;32:291-300.
    • (1998) Cytometry , vol.32 , pp. 291-300
    • Dowsett, M.1    Detre, S.2    Ormerod, M.G.3    Ellis, P.A.4    Mainwaring, P.N.5    Titley, J.C.6    Smith, I.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.