-
1
-
-
0027513355
-
Gene therapy, concepts, current trials and future directions
-
Tolstoshev P. Gene therapy, concepts, current trials and future directions. Annu Rev Pharmacol Toxicol 1993; 33: 573-596.
-
(1993)
Annu Rev Pharmacol Toxicol
, vol.33
, pp. 573-596
-
-
Tolstoshev, P.1
-
3
-
-
0027595949
-
The basic science of gene therapy
-
Mulligan RC. The basic science of gene therapy. Science 1993; 260: 926-932.
-
(1993)
Science
, vol.260
, pp. 926-932
-
-
Mulligan, R.C.1
-
5
-
-
0028886936
-
Gene therapy - A novel form of drug delivery
-
Blau HM. Gene therapy - a novel form of drug delivery. New Engl J Med 1995; 333: 1204-1207.
-
(1995)
New Engl J Med
, vol.333
, pp. 1204-1207
-
-
Blau, H.M.1
-
7
-
-
0029553015
-
Improved cationic lipid formulations for in vivo gene therapy
-
Felgner PL et al. Improved cationic lipid formulations for in vivo gene therapy. Ann NY Acad Sci 1995; 772: 126-139.
-
(1995)
Ann NY Acad Sci
, vol.772
, pp. 126-139
-
-
Felgner, P.L.1
-
8
-
-
0029617974
-
Current aspects of gene therapy: Implications for vascular interventions
-
Reifers F, Kreuzer J. Current aspects of gene therapy: implications for vascular interventions. J Mol Med 1995; 73: 595-602.
-
(1995)
J Mol Med
, vol.73
, pp. 595-602
-
-
Reifers, F.1
Kreuzer, J.2
-
10
-
-
0029376858
-
Gene therapy
-
Anderson WF. Gene therapy. Sci Am 1995; 273: 96-98.
-
(1995)
Sci Am
, vol.273
, pp. 96-98
-
-
Anderson, W.F.1
-
11
-
-
0029144835
-
Gene therapy's growing pains
-
Marshall E. Gene therapy's growing pains. Science 1995; 269: 1050-1055.
-
(1995)
Science
, vol.269
, pp. 1050-1055
-
-
Marshall, E.1
-
12
-
-
37049185656
-
Less hype, more biology needed for gene therapy
-
Marshall E. Less hype, more biology needed for gene therapy. Science 1995; 270: 1751.
-
(1995)
Science
, vol.270
, pp. 1751
-
-
Marshall, E.1
-
13
-
-
0028875936
-
Transfer of genes into humans: Early lessons and obstacles to success
-
Crystal R. Transfer of genes into humans: early lessons and obstacles to success. Science 1995; 270: 404-410.
-
(1995)
Science
, vol.270
, pp. 404-410
-
-
Crystal, R.1
-
15
-
-
0029932762
-
Folare-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer
-
Lee RJ, Huang L. Folare-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J Biol Chem 1996; 271: 8481-8487.
-
(1996)
J Biol Chem
, vol.271
, pp. 8481-8487
-
-
Lee, R.J.1
Huang, L.2
-
16
-
-
0025773499
-
Liposomes for the transformation of eukaryotic cells
-
Hug P, Sleight RG. Liposomes for the transformation of eukaryotic cells. Biochim Biophys Acta 1991; 1097: 1-17.
-
(1991)
Biochim Biophys Acta
, vol.1097
, pp. 1-17
-
-
Hug, P.1
Sleight, R.G.2
-
18
-
-
0025132571
-
Site-specific gene expression in vivo by direct gene transfer into the arterial wall
-
Nabel EG, Plautz G, Nabel GJ. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 1990; 249: 1285-1288.
-
(1990)
Science
, vol.249
, pp. 1285-1288
-
-
Nabel, E.G.1
Plautz, G.2
Nabel, G.J.3
-
19
-
-
0027250330
-
In vivo gene delivery: Efficient transfection of T lymphocytes in adult mice
-
Philip R et al. In vivo gene delivery: efficient transfection of T lymphocytes in adult mice. J Biol Chem 1993; 268: 16087-16090.
-
(1993)
J Biol Chem
, vol.268
, pp. 16087-16090
-
-
Philip, R.1
-
20
-
-
0027313072
-
Systemic gene expression after intravenous DNA delivery into adult mice
-
Zhu N, Liggitt D, Liu Y, Debs R. Systemic gene expression after intravenous DNA delivery into adult mice. Science 1993; 261: 209-211.
-
(1993)
Science
, vol.261
, pp. 209-211
-
-
Zhu, N.1
Liggitt, D.2
Liu, Y.3
Debs, R.4
-
21
-
-
0028812620
-
Cationic liposome-mediated intravenous gene delivery
-
Liu Y et al. Cationic liposome-mediated intravenous gene delivery. J Biol Chem 1995; 270: 24864-24870.
-
(1995)
J Biol Chem
, vol.270
, pp. 24864-24870
-
-
Liu, Y.1
-
22
-
-
0028822228
-
Systemic gene therapy: Biodistribution and long-term expression of a transgene in mice
-
Thierry AR et al. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. Proc Natl Acad Sci USA 1995; 92: 9742-9746
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9742-9746
-
-
Thierry, A.R.1
-
23
-
-
0028967275
-
Expression of the hepatitis C virus genome in rat liver after cationic liposome-mediated in vivo gene transfer
-
Takehara T et al. Expression of the hepatitis C virus genome in rat liver after cationic liposome-mediated in vivo gene transfer. Hepatology 1995; 21: 746-751.
-
(1995)
Hepatology
, vol.21
, pp. 746-751
-
-
Takehara, T.1
-
24
-
-
0028939896
-
Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: A stage toward artificial viruses
-
Remy J-S et al. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc Natl Acad Sci USA 1995; 92: 1744-1748.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1744-1748
-
-
Remy, J.-S.1
-
25
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
Zabner J et al. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270: 18997-19007.
-
(1995)
J Biol Chem
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
-
26
-
-
0030600235
-
Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes
-
Konopka K, Pretzer E, Felgner PL, Düzgüneş N. Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes. Biochim Biophys Acta 1996; 1312: 186-196.
-
(1996)
Biochim Biophys Acta
, vol.1312
, pp. 186-196
-
-
Konopka, K.1
Pretzer, E.2
Felgner, P.L.3
Düzgüneş, N.4
-
27
-
-
0031585174
-
Cationic liposome-mediated expression of HFV-regulated luciferase and diphtheria toxin A genes in HeLa cells infected with or expressing HIV
-
Konopka K, Harrison GS, Felgner PL, Düzgüneş N. Cationic liposome-mediated expression of HFV-regulated luciferase and diphtheria toxin A genes in HeLa cells infected with or expressing HIV. Biochim Biophys Acta 1997; 1356: 185-197.
-
(1997)
Biochim Biophys Acta
, vol.1356
, pp. 185-197
-
-
Konopka, K.1
Harrison, G.S.2
Felgner, P.L.3
Düzgüneş, N.4
-
28
-
-
0030977573
-
Editorial: Nomenclature for synthetic gene delivery systems
-
Felgner PL et al. Editorial: nomenclature for synthetic gene delivery systems. Hum Gene Ther 1997; 8: 511-512.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 511-512
-
-
Felgner, P.L.1
-
29
-
-
0011788754
-
Interaction between DOTMA liposomes, CV1 and U937 cells, and their isolated nuclei
-
Abstr.
-
Friend DS, Debs RJ, Düzgüneş N. Interaction between DOTMA liposomes, CV1 and U937 cells, and their isolated nuclei. J Cell Biol 1990; 111: 119a (Abstr.).
-
(1990)
J Cell Biol
, vol.111
-
-
Friend, D.S.1
Debs, R.J.2
Düzgüneş, N.3
-
30
-
-
0030071910
-
Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes
-
Friend DS, Papahadjopoulos D, Debs RJ. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim Biophys Acta 1996; 1278: 41-50.
-
(1996)
Biochim Biophys Acta
, vol.1278
, pp. 41-50
-
-
Friend, D.S.1
Papahadjopoulos, D.2
Debs, R.J.3
-
31
-
-
0028097638
-
DNA transfection mediated by cationic liposomes containing lipopolylysine: Characterization and mechanism of action
-
Zhou X, Huang L. DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta 1994; 1189: 195-203.
-
(1994)
Biochim Biophys Acta
, vol.1189
, pp. 195-203
-
-
Zhou, X.1
Huang, L.2
-
32
-
-
0029019120
-
Fusion of cationic liposomes with mammalian cells occurs after endocytosis
-
Wrobel I, Collins D. Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim Biophys Acta 1995; 1235: 296-304.
-
(1995)
Biochim Biophys Acta
, vol.1235
, pp. 296-304
-
-
Wrobel, I.1
Collins, D.2
-
33
-
-
0023642299
-
pH-dependent bilayer destabilization by an amphipathic peptide
-
Subbarao NK et al. pH-dependent bilayer destabilization by an amphipathic peptide. Biochemistry 1987; 26: 2964-2972.
-
(1987)
Biochemistry
, vol.26
, pp. 2964-2972
-
-
Subbarao, N.K.1
-
34
-
-
0023883581
-
pH-dependent fusion of phosphatidylcholine small vesicles
-
Parente RA, Nir S, Szoka FC Jr. pH-dependent fusion of phosphatidylcholine small vesicles. J Biol Chem 1988; 263: 4724-4730.
-
(1988)
J Biol Chem
, vol.263
, pp. 4724-4730
-
-
Parente, R.A.1
Nir, S.2
Szoka Jr., F.C.3
-
35
-
-
0026655684
-
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene-transfer vehicle
-
Wagner E et al. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 1992; 89: 7934-7938.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7934-7938
-
-
Wagner, E.1
-
36
-
-
0026645243
-
Membrane destabilization by N-terminal peptides of viral envelope proteins
-
Düzgüneş N, Shavnin SA. Membrane destabilization by N-terminal peptides of viral envelope proteins. J Mem Biol 1992; 128: 71-80.
-
(1992)
J Mem Biol
, vol.128
, pp. 71-80
-
-
Düzgüneş, N.1
Shavnin, S.A.2
-
37
-
-
0028199067
-
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems
-
Plank C et al. The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem 1994; 269: 12918-12924.
-
(1994)
J Biol Chem
, vol.269
, pp. 12918-12924
-
-
Plank, C.1
-
38
-
-
7344227213
-
Enhancement of cationic liposome-mediated gene delivery by transferrin and fusogenic peptides
-
Abstr.
-
Simões S et al. Enhancement of cationic liposome-mediated gene delivery by transferrin and fusogenic peptides. 24th Intl Symp Control Rel Bioact Mat, Stockholm 1997 (Abstr.).
-
(1997)
24th Intl Symp Control Rel Bioact Mat, Stockholm
-
-
Simões, S.1
-
39
-
-
7344228346
-
Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusogenic peptides
-
Coronado, CA, Abstr.
-
Düzgüneş N et al. Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusogenic peptides. Conf Artif Self-Assembling Syst Gene Del, Coronado, CA, 1997 (Abstr.).
-
(1997)
Conf Artif Self-Assembling Syst Gene Del
-
-
Düzgüneş, N.1
-
40
-
-
0025340966
-
Transferrin-polycation conjugates as carriers for DNA uptake into cells
-
Wagner E et al. Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci USA 1990; 87: 3410-3414.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3410-3414
-
-
Wagner, E.1
-
41
-
-
0030003605
-
Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages
-
Erbacher P et al. Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages. Hum Gene Ther 1996; 7: 721-729.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 721-729
-
-
Erbacher, P.1
-
42
-
-
0030046925
-
Receptor ligand-facilitated gene transfer: Enhancement of liposome-mediated gene transfer and expression by transferrin
-
Cheng PW. Receptor ligand-facilitated gene transfer: enhancement of liposome-mediated gene transfer and expression by transferrin. Hum Gene Ther 1996; 7: 275-282.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 275-282
-
-
Cheng, P.W.1
-
43
-
-
0027179724
-
Mode of formation and structural features of DNA-cationic liposome complexes used for transfection
-
Gershon H, Ghirlando R, Guttman SB, Minsky A. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry 1993; 32: 7143-7151
-
(1993)
Biochemistry
, vol.32
, pp. 7143-7151
-
-
Gershon, H.1
Ghirlando, R.2
Guttman, S.B.3
Minsky, A.4
-
44
-
-
0027399966
-
Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells
-
Legendre J-Y, Szoka FC Jr. Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells. Proc Natl Acad Sci USA 1993; 90: 893-897.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 893-897
-
-
Legendre, J.-Y.1
Szoka Jr., F.C.2
-
45
-
-
0028024919
-
Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations
-
Felgner JH et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994; 269: 2550-2561.
-
(1994)
J Biol Chem
, vol.269
, pp. 2550-2561
-
-
Felgner, J.H.1
-
46
-
-
0019884947
-
Studies on the mechanism of membrane fusion: Role of head-group composition in calcium- And magnesium-induced fusion of mixed phospholipid vesicles
-
Düzgüneş N, Wilschut J, Fraley R, Papahadjopoulos D. Studies on the mechanism of membrane fusion: role of head-group composition in calcium- and magnesium-induced fusion of mixed phospholipid vesicles. Biochim Biophys Acta 1981; 642: 182-195.
-
(1981)
Biochim Biophys Acta
, vol.642
, pp. 182-195
-
-
Düzgüneş, N.1
Wilschut, J.2
Fraley, R.3
Papahadjopoulos, D.4
-
47
-
-
0029067792
-
The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
-
Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acts 1995; 1235: 289-295.
-
(1995)
Biochim Biophys Acts
, vol.1235
, pp. 289-295
-
-
Farhood, H.1
Serbina, N.2
Huang, L.3
-
48
-
-
0011913143
-
Bafilomycins: A class of inhibitors of membrane ATPases from microorganisms, animal cells and plant cells
-
Bowman EJ, Siebers A, Altendorf K. Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells and plant cells. Proc Natl Acad Sci USA 1988; 85: 7972-7976.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 7972-7976
-
-
Bowman, E.J.1
Siebers, A.2
Altendorf, K.3
-
49
-
-
0025925091
-
+-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
-
+-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem 1991; 266: 17707-17712.
-
(1991)
J Biol Chem
, vol.266
, pp. 17707-17712
-
-
Yoshimori, T.1
-
50
-
-
0031104992
-
Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer
-
Kicher A, Mechtler K, Behr J-P, Wagner E. Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer. Bioconj Chem 1997; 8: 213-221.
-
(1997)
Bioconj Chem
, vol.8
, pp. 213-221
-
-
Kicher, A.1
Mechtler, K.2
Behr, J.-P.3
Wagner, E.4
-
51
-
-
0023447252
-
Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
-
Felgner PL et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7417.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
-
53
-
-
0002010524
-
Cationic liposome-mediated transfection: Effect of serum on expression and efficiency
-
Ciccarone V, Hawley-Nelson P, Jessee J. Cationic liposome-mediated transfection: effect of serum on expression and efficiency. Focus 1993; 15: 80-83.
-
(1993)
Focus
, vol.15
, pp. 80-83
-
-
Ciccarone, V.1
Hawley-Nelson, P.2
Jessee, J.3
-
54
-
-
0029790293
-
Lipidic supramolecular assemblies for gene transfer
-
Li S, Huang L. Lipidic supramolecular assemblies for gene transfer. J Liposome Res 1996; 6: 589-608.
-
(1996)
J Liposome Res
, vol.6
, pp. 589-608
-
-
Li, S.1
Huang, L.2
-
55
-
-
0027297678
-
Receptor-mediated transport of DNA into eukaryoric cells
-
Cotten M, Wagner E, Bimstiel ML. Receptor-mediated transport of DNA into eukaryoric cells. Meth Enzymol 1993; 217: 618-644.
-
(1993)
Meth Enzymol
, vol.217
, pp. 618-644
-
-
Cotten, M.1
Wagner, E.2
Bimstiel, M.L.3
-
56
-
-
0028332115
-
Amphiphilic peptides enhance the efficiency of liposome-mediated DNA transfection
-
Kamata H, Yagisawa H, Takahashi S, Hirata H. Amphiphilic peptides enhance the efficiency of liposome-mediated DNA transfection. Nucleic Acids Res 1994; 22: 536-537.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 536-537
-
-
Kamata, H.1
Yagisawa, H.2
Takahashi, S.3
Hirata, H.4
-
57
-
-
0025042733
-
Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA
-
Parente RA, Nir S, Szoka FC Jr. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry 1990; 29: 8720-8728.
-
(1990)
Biochemistry
, vol.29
, pp. 8720-8728
-
-
Parente, R.A.1
Nir, S.2
Szoka Jr., F.C.3
-
58
-
-
0028178521
-
Pore-forming peptides induce rapid phospholipid flip-flop in membranes
-
Fattal E, Nir S, Parente RA, Szoka FC Jr. Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry 1994; 33: 6721-6731.
-
(1994)
Biochemistry
, vol.33
, pp. 6721-6731
-
-
Fattal, E.1
Nir, S.2
Parente, R.A.3
Szoka Jr., F.C.4
-
59
-
-
4243463570
-
Transfection of human monocyte-derived macrophages by transferrin-cationic Iipid-DNA complexes
-
Simões S et al. Transfection of human monocyte-derived macrophages by transferrin-cationic Iipid-DNA complexes. FASEB J 1997; 11: A1090.
-
(1997)
FASEB J
, vol.11
-
-
Simões, S.1
-
60
-
-
0030927586
-
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery
-
Kircheis R et al. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery. Gene Therapy 1997; 4: 409-418.
-
(1997)
Gene Therapy
, vol.4
, pp. 409-418
-
-
Kircheis, R.1
-
61
-
-
0000956945
-
Gene transfer mediated by influenza virus peptides: The role of peptide sequences
-
Mechtler K, Wagner E. Gene transfer mediated by influenza virus peptides: the role of peptide sequences. New J Chem 1997; 21: 105-111.
-
(1997)
New J Chem
, vol.21
, pp. 105-111
-
-
Mechtler, K.1
Wagner, E.2
-
62
-
-
0027569924
-
Dual-attribute continuous monitoring of cell proliferation/cytotoxicity
-
Fields RD, Lancaster MV. Dual-attribute continuous monitoring of cell proliferation/cytotoxicity. Am Biotech Lab 1993; 11: 48-50.
-
(1993)
Am Biotech Lab
, vol.11
, pp. 48-50
-
-
Fields, R.D.1
Lancaster, M.V.2
|