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Volumn 57, Issue 3, 1999, Pages 409-438

Troglitazone: A review of its use in the management of type 2 diabetes mellitus

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; COLESTYRAMINE; CYCLOSPORIN; CYTOCHROME P450; GLIBENCLAMIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; LIVER ENZYME; METFORMIN; ORAL CONTRACEPTIVE AGENT; SULFONYLUREA; TERFENADINE; TRIACYLGLYCEROL; TROGLITAZONE;

EID: 0033022510     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-199957030-00014     Document Type: Review
Times cited : (105)

References (159)
  • 1
    • 0030746580 scopus 로고    scopus 로고
    • Troglitazone
    • Jul
    • Spencer CM, Markham A. Troglitazone. Drugs 1997 Jul; 54: 89-101
    • (1997) Drugs , vol.54 , pp. 89-101
    • Spencer, C.M.1    Markham, A.2
  • 2
    • 0003408870 scopus 로고
    • NIH Publication No. 95-1468, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda (MD)
    • Harris MI. Diabetes in America (2nd edition). NIH Publication No. 95-1468, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda (MD), 1995
    • (1995) Diabetes in America (2nd Edition)
    • Harris, M.I.1
  • 4
    • 0030317624 scopus 로고    scopus 로고
    • Pharmacologic treatment options for noninsulin-dependent diabetes mellitus
    • Aug
    • Tan GH, Nelson RL. Pharmacologic treatment options for noninsulin-dependent diabetes mellitus. Mayo Clin Proc 1996 Aug; 71: 763-8
    • (1996) Mayo Clin Proc , vol.71 , pp. 763-768
    • Tan, G.H.1    Nelson, R.L.2
  • 5
    • 84951664778 scopus 로고
    • Epidemiology of type II diabetes. An international perspective
    • Songer TJ, Zimmet PZ. Epidemiology of type II diabetes. An International perspective. Pharmacoeconomics 1995; 8 Suppl. 1: 1-11
    • (1995) Pharmacoeconomics , vol.8 , Issue.SUPPL. 1 , pp. 1-11
    • Songer, T.J.1    Zimmet, P.Z.2
  • 6
    • 0023757258 scopus 로고
    • Diabetes, hyperinsulinaemia and coronary risk factors in Bangladeshis in east London
    • McKeigue PM, Marmot MG, Syndercombe-Court YD, et al. Diabetes, hyperinsulinaemia and coronary risk factors in Bangladeshis in east London. Br Heart J 1988; 60: 990-6
    • (1988) Br Heart J , vol.60 , pp. 990-996
    • McKeigue, P.M.1    Marmot, M.G.2    Syndercombe-Court, Y.D.3
  • 7
    • 0030022820 scopus 로고    scopus 로고
    • The pharmacological treatment of hyperglycemia in NIDDM
    • Jan
    • The pharmacological treatment of hyperglycemia in NIDDM. Diabetes Care 1996 Jan; 19 Suppl. 1: 54-61
    • (1996) Diabetes Care , vol.19 , Issue.SUPPL. 1 , pp. 54-61
  • 8
    • 0030966013 scopus 로고    scopus 로고
    • Non-insulin dependent diabetes mellitus: The gathering storm
    • Mar 29
    • O'Rahilly S. Non-insulin dependent diabetes mellitus: the gathering storm. BMJ 1997 Mar 29; 314: 955-9
    • (1997) BMJ , vol.314 , pp. 955-959
    • O'Rahilly, S.1
  • 9
    • 0029366188 scopus 로고
    • Prevalence and secular trends in obesity in Pacific and Indian Ocean island populations
    • Hodge AM, Dowse GK, Zimmet PZ, et al. Prevalence and secular trends in obesity in Pacific and Indian Ocean island populations. Obesity Research 1995; 3 Suppl. 2: 77s-87s
    • (1995) Obesity Research , vol.3 , Issue.SUPPL. 2
    • Hodge, A.M.1    Dowse, G.K.2    Zimmet, P.Z.3
  • 10
    • 0030463794 scopus 로고    scopus 로고
    • Oral antidiabetic drug use in the elderly
    • Dec
    • Bressler R, Johnson DG. Oral antidiabetic drug use in the elderly. Drugs Aging 1996 Dec; 9: 418-37
    • (1996) Drugs Aging , vol.9 , pp. 418-437
    • Bressler, R.1    Johnson, D.G.2
  • 11
    • 0029920573 scopus 로고    scopus 로고
    • New therapeutic agents for the treatment or NIDDM
    • Kuehnle HF. New therapeutic agents for the treatment or NIDDM. Exp Clin Endocrinol Diabetes 1996; 104 (2):93-101
    • (1996) Exp Clin Endocrinol Diabetes , vol.104 , Issue.2 , pp. 93-101
    • Kuehnle, H.F.1
  • 12
    • 0029995670 scopus 로고    scopus 로고
    • Thiazolidinediones in the treatment of insulin resistance and type II diabetes
    • Dec
    • Saltiel AR, Olefsky JM. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 1996 Dec; 45: 1661-9
    • (1996) Diabetes , vol.45 , pp. 1661-1669
    • Saltiel, A.R.1    Olefsky, J.M.2
  • 14
    • 0030033975 scopus 로고    scopus 로고
    • Cardiovascular complications of diabetes mellitus: What we know and what we need to know about their prevention
    • Jan 1
    • Savage PJ. Cardiovascular complications of diabetes mellitus: what we know and what we need to know about their prevention. Ann Intern Med 1996 Jan 1; 124 (Pt 2): 123-6
    • (1996) Ann Intern Med , vol.124 , Issue.PART 2 , pp. 123-126
    • Savage, P.J.1
  • 15
    • 0029972654 scopus 로고    scopus 로고
    • Treatment of dyslipoproteinaemia in diabetes mellitus
    • Apr
    • Dean JD, Durrington PN. Treatment of dyslipoproteinaemia in diabetes mellitus. Diabetic Med 1996 Apr; 13: 297-312
    • (1996) Diabetic Med , vol.13 , pp. 297-312
    • Dean, J.D.1    Durrington, P.N.2
  • 16
    • 0030848518 scopus 로고    scopus 로고
    • Cumulative glycemic exposure and microvascular complications in insulin-dependent diabetes mellitus
    • Orchard TJ, Forrest KY-Z, Ellis D, et al. Cumulative glycemic exposure and microvascular complications in insulin-dependent diabetes mellitus. Arch Intern Med 1997; 157 (1851-1856)
    • (1997) Arch Intern Med , vol.157 , Issue.1851-1856
    • Orchard, T.J.1    Forrest, K.Y.-Z.2    Ellis, D.3
  • 17
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • Sep 12
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998 Sep 12; 352: 837-53
    • (1998) Lancet , vol.352 , pp. 837-853
  • 18
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • Sep 12
    • UK Prospective Diabetes study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998 Sep 12; 352: 854-65
    • (1998) Lancet , vol.352 , pp. 854-865
  • 19
    • 10544234410 scopus 로고
    • Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes VII: Mortality and selected nonfatal events with insulin treatment
    • University Group Diabetes Program. Effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes VII: mortality and selected nonfatal events with insulin treatment. JAMA 1978; 240: 37-42
    • (1978) JAMA , vol.240 , pp. 37-42
  • 20
    • 0032511606 scopus 로고    scopus 로고
    • Some answers, more controversy, from UKPDS
    • Sept 12
    • Nathan DM. Some answers, more controversy, from UKPDS [commentary]. Lancet 1998 Sept 12; 352: 832-3
    • (1998) Lancet , vol.352 , pp. 832-833
    • Nathan, D.M.1
  • 21
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329: 977-86
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 22
  • 24
    • 0032037738 scopus 로고    scopus 로고
    • PPARy activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes
    • Martin G, Schoonjans K, Staels B, et al. PPARy activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytes. Atherosclerosis 1998; 137 Suppl: S75-80
    • (1998) Atherosclerosis , vol.137 , Issue.SUPPL.
    • Martin, G.1    Schoonjans, K.2    Staels, B.3
  • 25
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptory (PPARγ)
    • Lehmann JM, Moore LB, Smith-Oliver TA, et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptory (PPARγ). J Biol Chem 1995; 270 (22): 12953-6
    • (1995) J Biol Chem , vol.270 , Issue.22 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3
  • 26
    • 0029745382 scopus 로고    scopus 로고
    • Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated rcceptor-γ. Binding and activation correlated with antidiabetic actions in db/db mice
    • Berger J, Bailey P, Biswas C, et al. Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated rcceptor-γ. binding and activation correlated with antidiabetic actions in db/db mice. Endocrinology 1996; 137 (10): 4189-95
    • (1996) Endocrinology , vol.137 , Issue.10 , pp. 4189-4195
    • Berger, J.1    Bailey, P.2    Biswas, C.3
  • 27
    • 0030062325 scopus 로고    scopus 로고
    • The structure-activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones
    • Wilson TM, Cobb JE, Cowan DJ, et al. The structure-activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 1996; 39: 665-8
    • (1996) J Med Chem , vol.39 , pp. 665-668
    • Wilson, T.M.1    Cobb, J.E.2    Cowan, D.J.3
  • 28
    • 0000785413 scopus 로고    scopus 로고
    • Investigation of twice or three times daily dose regimen of troglitazone, an insulin action enhancer, in patients with non insulin dependent diabetes mellitus
    • Corrêa JCN, Hilsted J, Eckland D, et al. Investigation of twice or three times daily dose regimen of troglitazone, an insulin action enhancer, in patients with non insulin dependent diabetes mellitus. Eur J Clin Res 1997; 9: 151-65
    • (1997) Eur J Clin Res , vol.9 , pp. 151-165
    • Corrêa, J.C.N.1    Hilsted, J.2    Eckland, D.3
  • 29
    • 7844236780 scopus 로고    scopus 로고
    • Troglitazone monotherapy improves glycemic control in patients with type 2 diabetes mellitus: A randomized, controlled study
    • Fonseca VA, Valiquett TR, Huang SM, et al. Troglitazone monotherapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled study. J Clin Endocrinol Metab 1998; 83: 3169-76
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3169-3176
    • Fonseca, V.A.1    Valiquett, T.R.2    Huang, S.M.3
  • 30
    • 0029999139 scopus 로고    scopus 로고
    • Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients
    • Jun
    • Kumar S, Boulton AJM, Beck-Nielsen H, et al. Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients. Diabetologia 1996 Jun; 39: 701-9
    • (1996) Diabetologia , vol.39 , pp. 701-709
    • Kumar, S.1    Boulton, A.J.M.2    Beck-Nielsen, H.3
  • 31
    • 0030862984 scopus 로고    scopus 로고
    • Double-masked, placebo-controlled, dose-ranging study of troglitazone 10 to 200 mg once daily in non-insulin-dependent diabetes mellitus
    • Jul
    • Leutenegger M, Sacca L, Alderton C, et al. Double-masked, placebo-controlled, dose-ranging study of troglitazone 10 to 200 mg once daily in non-insulin-dependent diabetes mellitus. Curr Ther Res Clin Exp 1997 Jul; 58: 403-16
    • (1997) Curr Ther Res Clin Exp , vol.58 , pp. 403-416
    • Leutenegger, M.1    Sacca, L.2    Alderton, C.3
  • 32
    • 0024160854 scopus 로고
    • Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats
    • Nov
    • Fujiwara T, Yoshioka S, Yoshioka T, et al. Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats [in English]. Diabetes 1988 Nov; 37: 1549-58
    • (1988) Diabetes , vol.37 , pp. 1549-1558
    • Fujiwara, T.1    Yoshioka, S.2    Yoshioka, T.3
  • 33
    • 0030831845 scopus 로고    scopus 로고
    • Acute non-insulin-like stimulation of rat muscle glucose metabolism by troglitazone in vitro
    • Dec
    • Fürnsinn C, Neschen S, Noe C, et al. Acute non-insulin-like stimulation of rat muscle glucose metabolism by troglitazone in vitro. Br J Pharmacol 1997 Dec; 122: 1367-74
    • (1997) Br J Pharmacol , vol.122 , pp. 1367-1374
    • Fürnsinn, C.1    Neschen, S.2    Noe, C.3
  • 34
    • 0025166078 scopus 로고
    • Insulin-like activity of new antidiabetic agent CP68722 in 3T3-L1 adipocytes
    • Kreutter DK, Andrews KM, Gibbs EM, et al. Insulin-like activity of new antidiabetic agent CP68722 in 3T3-L1 adipocytes. Diabetes 1990; 39: 1414-9
    • (1990) Diabetes , vol.39 , pp. 1414-1419
    • Kreutter, D.K.1    Andrews, K.M.2    Gibbs, E.M.3
  • 35
    • 0029555475 scopus 로고
    • Acute effects of troglitazone on in vivo insulin action in normal rats
    • Sep
    • Lee MK, Olefsky JM. Acute effects of troglitazone on in vivo insulin action in normal rats. Metabolism 1995 Sep; 44: 1166-9
    • (1995) Metabolism , vol.44 , pp. 1166-1169
    • Lee, M.K.1    Olefsky, J.M.2
  • 36
    • 0030996501 scopus 로고    scopus 로고
    • Acute effect of troglitazone on glucose metabolism in the absence or presence of insulin in perfused rat hindlimb
    • Jun
    • Okuno A, Ikeda K, Shiota M, et al. Acute effect of troglitazone on glucose metabolism in the absence or presence of insulin in perfused rat hindlimb. Metabolism 1997 Jun; 46: 716-21
    • (1997) Metabolism , vol.46 , pp. 716-721
    • Okuno, A.1    Ikeda, K.2    Shiota, M.3
  • 37
    • 7844248273 scopus 로고    scopus 로고
    • Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects
    • May
    • Park KS, Ciaraldi TP, Abrams-Carter L, et al. Troglitazone regulation of glucose metabolism in human skeletal muscle cultures from obese type II diabetic subjects. J Clin Endocrinol Metab 1998 May; 83: 1636-43
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1636-1643
    • Park, K.S.1    Ciaraldi, T.P.2    Abrams-Carter, L.3
  • 38
    • 0028916523 scopus 로고
    • Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-α on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells
    • Apr
    • Szalkowski D, White-Carrington S, Berger J, et al. Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-α on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells. Endocrinology 1995 Apr; 136: 1474-81
    • (1995) Endocrinology , vol.136 , pp. 1474-1481
    • Szalkowski, D.1    White-Carrington, S.2    Berger, J.3
  • 39
    • 0031029934 scopus 로고    scopus 로고
    • Effects of troglitazone on in vitro oxidation of LDL and HDL induced by copper ions and endothelial cells
    • Feb
    • Cominacini L, Garbin U, Pastorino AM, et al. Effects of troglitazone on in vitro oxidation of LDL and HDL induced by copper ions and endothelial cells. Diabetologia 1997 Feb; 40: 165-72
    • (1997) Diabetologia , vol.40 , pp. 165-172
    • Cominacini, L.1    Garbin, U.2    Pastorino, A.M.3
  • 40
    • 0031048299 scopus 로고    scopus 로고
    • Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis
    • Steinberg D. Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis. Circulation 1997; 95: 1062-71
    • (1997) Circulation , vol.95 , pp. 1062-1071
    • Steinberg, D.1    Lewis, A.2
  • 41
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyle inflammatory cytokines
    • Jan 1
    • Jiang C, Ting AT, Seed B. PPAR-γ agonists inhibit production of monocyle inflammatory cytokines. Nature 1998 Jan 1; 391: 82-6
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 42
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P, Nagy L, Alvarez JG, et al. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998; 93 (2): 241-52
    • (1998) Cell , vol.93 , Issue.2 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3
  • 43
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, et al. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998; 93 (2): 229-40
    • (1998) Cell , vol.93 , Issue.2 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3
  • 44
    • 0031560952 scopus 로고    scopus 로고
    • Troglitazone has a scavenging effect on reactive oxygen species
    • Inoue I, Katayama S, Takahashi K, et al. Troglitazone has a scavenging effect on reactive oxygen species. Biochem Biophys Res Commum 1997; 235: 113A-6A
    • (1997) Biochem Biophys Res Commum , vol.235
    • Inoue, I.1    Katayama, S.2    Takahashi, K.3
  • 45
    • 0030661983 scopus 로고    scopus 로고
    • TNF-α-induced insulin resistance in vivo and its prevention by troglitazone
    • Nov
    • Miles PDG, Romeo OM, Higo K, et al. TNF-α-induced insulin resistance in vivo and its prevention by troglitazone. Diabetes 1997 Nov; 46: 1678-83
    • (1997) Diabetes , vol.46 , pp. 1678-1683
    • Miles, P.D.G.1    Romeo, O.M.2    Higo, K.3
  • 46
    • 9844230954 scopus 로고    scopus 로고
    • Troglitazone increases the resistance of low density lipoprotein to oxidation in healthy volunteers
    • Oct
    • Cominacini L, Young MMR, Capriati A, et al. Troglitazone increases the resistance of low density lipoprotein to oxidation in healthy volunteers. Diabetologia 1997 Oct; 40: 1211-8
    • (1997) Diabetologia , vol.40 , pp. 1211-1218
    • Cominacini, L.1    Young, M.M.R.2    Capriati, A.3
  • 47
    • 17744404395 scopus 로고    scopus 로고
    • Troglitazone reduces LDL oxidation and lowers plasma E-selectin concentration in NIDDM patients
    • Jan
    • Cominacini L, Garbin U, Fratta-Pasini A, et al. Troglitazone reduces LDL oxidation and lowers plasma E-selectin concentration in NIDDM patients. Diabetes 1998 Jan; 47: 130-3
    • (1998) Diabetes , vol.47 , pp. 130-133
    • Cominacini, L.1    Garbin, U.2    Fratta-Pasini, A.3
  • 48
    • 0031736142 scopus 로고    scopus 로고
    • Troglitazone decreases the proportion of small, dense LDL and increases the resistance of LDL to oxidation in obese subjects
    • May
    • Tack CJJ, Smits P, Demacker PNM, et al. Troglitazone decreases the proportion of small, dense LDL and increases the resistance of LDL to oxidation in obese subjects. Diabetes Care 1998 May; 21: 796-9
    • (1998) Diabetes Care , vol.21 , pp. 796-799
    • Tack, C.J.J.1    Smits, P.2    Demacker, P.N.M.3
  • 49
    • 0031438497 scopus 로고    scopus 로고
    • Circulating adhesion molecules VCAM-1, ICAM-1 and E-selectin in carotid atherosclerosis and incident coronary heart disease cases. The Atherosclerosis Risk in Communities (ARIC) Study
    • Hwang S-J, Ballantyne CM, Sharrett AR, et al. Circulating adhesion molecules VCAM-1, ICAM-1 and E-selectin in carotid atherosclerosis and incident coronary heart disease cases. The Atherosclerosis Risk in Communities (ARIC) Study. Circulation 1997; 96: 4219-25
    • (1997) Circulation , vol.96 , pp. 4219-4225
    • Hwang, S.-J.1    Ballantyne, C.M.2    Sharrett, A.R.3
  • 50
    • 0028937422 scopus 로고
    • Suppression of hepatic gluconeogenesis in long-term troglitazone treated diabetic KK and C57BL/KsJ-db/db mice
    • Apr
    • Fujiwara T, Okuno A, Yoshioka S, et al. Suppression of hepatic gluconeogenesis in long-term troglitazone treated diabetic KK and C57BL/KsJ-db/db mice. Metabolism 1995 Apr; 44: 486-90
    • (1995) Metabolism , vol.44 , pp. 486-490
    • Fujiwara, T.1    Okuno, A.2    Yoshioka, S.3
  • 52
    • 0029553537 scopus 로고
    • Effect of troglitazone (CS-045) and bezafibrate on glucose tolerance, liver glycogen synthase activity, and β-oxidation in fructose-fed rats
    • Dec
    • Inoue I, Takahashi K, Katayama S, et al. Effect of troglitazone (CS-045) and bezafibrate on glucose tolerance, liver glycogen synthase activity, and β-oxidation in fructose-fed rats. Metabolism 1995 Dec; 44: 1626-30
    • (1995) Metabolism , vol.44 , pp. 1626-1630
    • Inoue, I.1    Takahashi, K.2    Katayama, S.3
  • 53
    • 0029551666 scopus 로고
    • Metabolic effects of troglitazone on fat-induced insulin resistance in the rat
    • Nov
    • Khoursheed M, Miles PD, Gao KM, et al. Metabolic effects of troglitazone on fat-induced insulin resistance in the rat. Metabolism 1995 Nov; 44: 1489-94
    • (1995) Metabolism , vol.44 , pp. 1489-1494
    • Khoursheed, M.1    Miles, P.D.2    Gao, K.M.3
  • 54
    • 0028598170 scopus 로고
    • Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat
    • Dec
    • Lee M-K. Miles PDG, Khoursheed M, et al. Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat. Diabetes 1994 Dec; 43: 1435-9
    • (1994) Diabetes , vol.43 , pp. 1435-1439
    • Lee, M.-K.1    Miles, P.D.G.2    Khoursheed, M.3
  • 55
    • 0028849029 scopus 로고
    • Effect of troglitazone, a new oral antidiabetic agent, on fructose-induced insulin resistance
    • Oct
    • Yagi N, Takasu N, Higa S, et al. Effect of troglitazone, a new oral antidiabetic agent, on fructose-induced insulin resistance. Horm Metab Res 1995 Oct; 27: 439-41
    • (1995) Horm Metab Res , vol.27 , pp. 439-441
    • Yagi, N.1    Takasu, N.2    Higa, S.3
  • 56
    • 0029911310 scopus 로고    scopus 로고
    • Amelioration of hyperglycemia in streptozotocin-induced diabetic rats receiving a marginal mass of islet grafts by troglitazone, an oral antidiabetic agent
    • Nagai T, Yasunami Y, Nagata N, et al. Amelioration of hyperglycemia in streptozotocin-induced diabetic rats receiving a marginal mass of islet grafts by troglitazone, an oral antidiabetic agent. Pancreas 1996; 13 (4): 381-7
    • (1996) Pancreas , vol.13 , Issue.4 , pp. 381-387
    • Nagai, T.1    Yasunami, Y.2    Nagata, N.3
  • 57
    • 0027304282 scopus 로고
    • Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats
    • Jun
    • Tominaga M, Igarashi M, Daimon M, et al. Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats. Endocr J 1993 Jun; 40: 343-9
    • (1993) Endocr J , vol.40 , pp. 343-349
    • Tominaga, M.1    Igarashi, M.2    Daimon, M.3
  • 58
    • 0025938575 scopus 로고
    • Characterization of SC045, a new oral antidiabetic agent II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KSJ-db/db mice
    • Fujiwara T, Wade M, Fukuda K, et al. Characterization of SC045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KSJ-db/db mice. Metabolism 1991; 40: 1213-8
    • (1991) Metabolism , vol.40 , pp. 1213-1218
    • Fujiwara, T.1    Wade, M.2    Fukuda, K.3
  • 59
    • 0031767928 scopus 로고    scopus 로고
    • Effect of troglitazone on B cell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus
    • Mar
    • Prigeon RL, Kahn SE, Porte JD. Effect of troglitazone on B cell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 1998 Mar; 83: 819-23
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 819-823
    • Prigeon, R.L.1    Kahn, S.E.2    Porte, J.D.3
  • 60
    • 0032568257 scopus 로고    scopus 로고
    • Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus
    • Mar 26
    • Inzucchi SE, Maggs DG, Spollett GR, et al. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N Engl J Med 1998 Mar 26; 338: 867-72
    • (1998) N Engl J Med , vol.338 , pp. 867-872
    • Inzucchi, S.E.1    Maggs, D.G.2    Spollett, G.R.3
  • 61
    • 0032005178 scopus 로고    scopus 로고
    • Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled trial
    • Feb 1
    • Maggs DG, Buchanan TA, Burant CF, et al. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1998 Feb 1; 128: 176-85
    • (1998) Ann Intern Med , vol.128 , pp. 176-185
    • Maggs, D.G.1    Buchanan, T.A.2    Burant, C.F.3
  • 62
    • 0026517631 scopus 로고
    • Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects
    • Feb
    • Suter SL, Nolan JJ, Wallace R et al. Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care 1992 Feb; 15: 193-203
    • (1992) Diabetes Care , vol.15 , pp. 193-203
    • Suter, S.L.1    Nolan, J.J.2    Wallace, R.3
  • 63
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nov 3
    • Nolan JJ, Ludvik B, Beerdsen P, et al. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 1994 Nov 3; 331: 1188-93
    • (1994) N Engl J Med , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3
  • 64
    • 0032850352 scopus 로고    scopus 로고
    • Ann Arbor (MI): Department of Pharmacokinetics, Dynamics and Metabolism, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, (Data on file)
    • Loi C-M, Young M, Randinitis E, et al. Clinical pharmacokinetics of troglitazone. Ann Arbor (MI): Department of Pharmacokinetics, Dynamics and Metabolism, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, 1999. (Data on file)
    • (1999) Clinical Pharmacokinetics of Troglitazone
    • Loi, C.-M.1    Young, M.2    Randinitis, E.3
  • 66
    • 0001020521 scopus 로고
    • Phase I study of a new hypoglycemic agcnt CS-045 in healthy volunteers. Safety and pharmacokinetics in single administration
    • Shibata H, Nii S, Kobayashi M, et al. Phase I study of a new hypoglycemic agcnt CS-045 in healthy volunteers. Safety and pharmacokinetics in single administration [in Japanese]. Rinsho Iyaku 1993; 9 (7): 1503-18
    • (1993) Rinsho Iyaku , vol.9 , Issue.7 , pp. 1503-1518
    • Shibata, H.1    Nii, S.2    Kobayashi, M.3
  • 67
    • 0001397802 scopus 로고    scopus 로고
    • Similar pharmacokinetics of troglitazone in young and elderly subjects
    • Aug
    • Young MA, Williams ZV, Eastmond R. Similar pharmacokinetics of troglitazone in young and elderly subjects [abstract]. Diabetologia 1996 Aug; 39 Suppl. 1: A233
    • (1996) Diabetologia , vol.39 , Issue.SUPPL. 1
    • Young, M.A.1    Williams, Z.V.2    Eastmond, R.3
  • 68
    • 0031406407 scopus 로고    scopus 로고
    • Lack of effect of type II diabetes on the pharmacokinetics of troglitazone in a multiple-dose study
    • Dec
    • Loi C-M, Randinitis EJ, Vassos AB, et al. Lack of effect of type II diabetes on the pharmacokinetics of troglitazone in a multiple-dose study. J Clin Pharmacol 1997 Dec; 37: 1114-20.
    • (1997) J Clin Pharmacol , vol.37 , pp. 1114-1120
    • Loi, C.-M.1    Randinitis, E.J.2    Vassos, A.B.3
  • 69
    • 0008861608 scopus 로고    scopus 로고
    • Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs
    • Apr
    • Kawai K, Kawasaki-Tokui Y, Odaka T, et al. Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs. Arzneimittel Forschung 1997 Apr; 47: 356-68
    • (1997) Arzneimittel Forschung , vol.47 , pp. 356-368
    • Kawai, K.1    Kawasaki-Tokui, Y.2    Odaka, T.3
  • 70
    • 0028903834 scopus 로고
    • High-performance frontal analysis for the study of protein binding of troglitazone (CS-045) in albumin solution and in human plasma
    • Apr 21
    • Shibukawa A, Sawada T, Nakao C, et al. High-performance frontal analysis for the study of protein binding of troglitazone (CS-045) in albumin solution and in human plasma. J Chromatogr A 1995 Apr 21; 697: 337-43
    • (1995) J Chromatogr A , vol.697 , pp. 337-343
    • Shibukawa, A.1    Sawada, T.2    Nakao, C.3
  • 71
    • 0013604679 scopus 로고
    • Pharmacokinetics study of a new oral hypoglycemic agent CS-045 in patients with non-insulin dependent diabetes mellitus [in Japanese]
    • Yamanouchi T, Shinohara T, Tagaya T, et al. Pharmacokinetics study of a new oral hypoglycemic agent CS-045 in patients with non-insulin dependent diabetes mellitus [in Japanese]. Rinsho Iyaku 1995; 11 (11): 2325-39
    • (1995) Rinsho Iyaku , vol.11 , Issue.11 , pp. 2325-2339
    • Yamanouchi, T.1    Shinohara, T.2    Tagaya, T.3
  • 72
    • 0031764673 scopus 로고    scopus 로고
    • Pharmacokinetics of troglitazone, a PPAR-γ agonist, in patients with hepatic insufficiency
    • Ott P, Ranek L, Young MA. Pharmacokinetics of troglitazone, a PPAR-γ agonist, in patients with hepatic insufficiency. Eur J Clin Pharmacol 1998; 54: 567-71
    • (1998) Eur J Clin Pharmacol , vol.54 , pp. 567-571
    • Ott, P.1    Ranek, L.2    Young, M.A.3
  • 73
    • 0031907647 scopus 로고    scopus 로고
    • Improvement in the gastrointestinal absorption of troglitazone when taken with, or shortly after, food
    • Jan
    • Young MA, Lettis S, Eastmond R. Improvement in the gastrointestinal absorption of troglitazone when taken with, or shortly after, food. Br J Clin Pharmacol 1998 Jan; 45: 31-5
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 31-35
    • Young, M.A.1    Lettis, S.2    Eastmond, R.3
  • 74
    • 0029795871 scopus 로고    scopus 로고
    • The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome
    • Sep
    • Dunaif A, Scott D, Finegood D, et al. The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. J Clin Endocrinol Metab 1996 Sep; 81: 3299-306
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3299-3306
    • Dunaif, A.1    Scott, D.2    Finegood, D.3
  • 75
    • 0030855145 scopus 로고    scopus 로고
    • Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome
    • Jul
    • Ehrmann DA, Schneider DJ, Sobel BE, et al. Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 1997 Jul; 82: 2108-16
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2108-2116
    • Ehrmann, D.A.1    Schneider, D.J.2    Sobel, B.E.3
  • 76
    • 8544242764 scopus 로고    scopus 로고
    • Troglitazone ameliorates insulin resistance in patients with Werner's syndrome
    • Aug
    • Izumino K, Sakamaki H, Ishibashi M, et al. Troglitazone ameliorates insulin resistance in patients with Werner's syndrome. J Clin Endocrinol Metab 1997 Aug; 82: 2391-5
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2391-2395
    • Izumino, K.1    Sakamaki, H.2    Ishibashi, M.3
  • 77
    • 0027931599 scopus 로고
    • Increased insulin responsiveness after CS-045 treatment in diabetes associated with Werner's syndrome
    • Jul
    • Takino H, Okuno S, Uotani S, et al. Increased insulin responsiveness after CS-045 treatment in diabetes associated with Werner's syndrome. Diabetes Res Clin Pract 1994 Jul; 24: 167-72
    • (1994) Diabetes Res Clin Pract , vol.24 , pp. 167-172
    • Takino, H.1    Okuno, S.2    Uotani, S.3
  • 78
    • 26444509462 scopus 로고
    • Pancreatic hormones & diabetes mellitus
    • Greenspan FS, editor. Morwalk (CT): Appleton & Lange
    • Karam JH, Salber PR, Forsham PH. Pancreatic hormones & diabetes mellitus. In: Greenspan FS, editor. Basic and clinical endocrinology. 3rd ed. Morwalk (CT): Appleton & Lange, 1991: 592-650
    • (1991) Basic and Clinical Endocrinology. 3rd Ed. , pp. 592-650
    • Karam, J.H.1    Salber, P.R.2    Forsham, P.H.3
  • 79
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 80
    • 0029862973 scopus 로고    scopus 로고
    • Hyperinsulinemia as an independent risk factor for ischemic heart disease
    • Després J-P, Lamarche B, Mauriège P, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996; 334: 952-7
    • (1996) N Engl J Med , vol.334 , pp. 952-957
    • Després, J.-P.1    Lamarche, B.2    Mauriège, P.3
  • 81
    • 0008504314 scopus 로고
    • Effects of troglitazone, a thiazolidinedione, in elderly non-insulin-dependent diabetic patients
    • Hansen AP, Troglitazone Study Group. Effects of troglitazone, a thiazolidinedione, in elderly non-insulin-dependent diabetic patients [abstract]. Diabetologia 1995; 38 Suppl. 1: A200
    • (1995) Diabetologia , vol.38 , Issue.SUPPL. 1
    • Hansen, A.P.1
  • 82
    • 0031858068 scopus 로고    scopus 로고
    • Troglitazone, an insulin action enhancer, improves glycaemic control and insulin sensitivity in elderly type 2 diabetic patients
    • Kumar S, Prange A, Schulze J, et al. Troglitazone, an insulin action enhancer, improves glycaemic control and insulin sensitivity in elderly type 2 diabetic patients. Diabetic Med 1998; 15: 772-9
    • (1998) Diabetic Med , vol.15 , pp. 772-779
    • Kumar, S.1    Prange, A.2    Schulze, J.3
  • 83
    • 4243397361 scopus 로고    scopus 로고
    • Efficacy of troglitazone in young and elderly patients with NIDDM
    • May
    • Okamoto M, Okamoto M, Taniguchi T, et al. Efficacy of troglitazone in young and elderly patients with NIDDM [abstract]. Diabetes 1998 May; 47 Suppl. 1: A97
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Okamoto, M.1    Okamoto, M.2    Taniguchi, T.3
  • 84
    • 0002434196 scopus 로고    scopus 로고
    • Troglitazone improves cardiovascular risk profile compared with glibenclamide
    • Claudi T, Starkie M, Frith L, et al. Troglitazone improves cardiovascular risk profile compared with glibenclamide [abstract]. Diabetic Med 1997; 14 Suppl. 4: 30
    • (1997) Diabetic Med , vol.14 , Issue.SUPPL. 4 , pp. 30
    • Claudi, T.1    Starkie, M.2    Frith, L.3
  • 85
    • 0031054699 scopus 로고    scopus 로고
    • Cardiac and glycemic benefits of troglitazone treatment in NIDDM
    • Mar
    • Ghazzi MN, Perez JE, Antonucci TK, et al. Cardiac and glycemic benefits of troglitazone treatment in NIDDM. Diabetes 1997 Mar; 46: 433-9
    • (1997) Diabetes , vol.46 , pp. 433-439
    • Ghazzi, M.N.1    Perez, J.E.2    Antonucci, T.K.3
  • 86
    • 0013601088 scopus 로고    scopus 로고
    • Metabolic effects of troglitazone in NIDDM patients
    • May
    • Levin K, Thye-Rømn P, Foot E, et al. Metabolic effects of troglitazone in NIDDM patients [abstract]. Diabetes 1996 May; 45 Suppl. 2: 18A
    • (1996) Diabetes , vol.45 , Issue.SUPPL. 2
    • Levin, K.1    Thye-Rømn, P.2    Foot, E.3
  • 87
    • 4243351666 scopus 로고    scopus 로고
    • The effects of troglitazone on lipolysis, fatty acid mobilization, and glucose turnover in NIDDM
    • Robinson ACJ, Gray RG, Bannister PA, et al. The effects of troglitazone on lipolysis, fatty acid mobilization, and glucose turnover in NIDDM [abstract]. Diabetic Med 1998; 15 Suppl. 1: S66
    • (1998) Diabetic Med , vol.15 , Issue.SUPPL. 1
    • Robinson, A.C.J.1    Gray, R.G.2    Bannister, P.A.3
  • 88
    • 4243397360 scopus 로고    scopus 로고
    • Troglitgazone (600 mg daily) reduces the rate of very low density synthesis and pool size in patients with NIDDM
    • Rosinson ACJ, Gray RG, Bannister PA, et al. Troglitgazone (600 mg daily) reduces the rate of very low density synthesis and pool size in patients with NIDDM [abstract]. Diabetic Med 1998. 15 Suppl. 1: S29
    • (1998) Diabetic Med , vol.15 , Issue.SUPPL. 1
    • Rosinson, A.C.J.1    Gray, R.G.2    Bannister, P.A.3
  • 89
    • 0002523085 scopus 로고    scopus 로고
    • Troglitazone improves insulin resistance compared to metformin
    • Serrano-Rios M, Kler L, Frith L, et al. Troglitazone improves insulin resistance compared to metformin [abstract]. Diabetic Med 1997; 14 Suppl. 4: 22
    • (1997) Diabetic Med , vol.14 , Issue.SUPPL. 4 , pp. 22
    • Serrano-Rios, M.1    Kler, L.2    Frith, L.3
  • 90
    • 0030868981 scopus 로고    scopus 로고
    • Effects of troglitazone on insulin action and cardiovascular risk factors in patients with non-insulin-dependent diabetes
    • Aug
    • Sironi AM, Vichi S, Gastaldelli A, et al. Effects of troglitazone on insulin action and cardiovascular risk factors in patients with non-insulin-dependent diabetes. Clin Pharmacol Ther 1997 Aug; 62: 194-202
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 194-202
    • Sironi, A.M.1    Vichi, S.2    Gastaldelli, A.3
  • 91
    • 0001541182 scopus 로고    scopus 로고
    • The metabolic effects of troglitazone in non-insulin dependent diabetes
    • Jun
    • Troglitazone Study Group. The metabolic effects of troglitazone in non-insulin dependent diabetes [abstract]. Diabetologia 1997 Jun; 40 Suppl. 1: 149A
    • (1997) Diabetologia , vol.40 , Issue.SUPPL. 1
  • 92
    • 0000364850 scopus 로고
    • Troglitazone dose-response study in patients with NIDDM
    • May
    • Valiquett T, Balagtas C, Whitcomb R. Troglitazone dose-response study in patients with NIDDM [abstract]. Diabetes 1995 May; 44 Suppl. 1: 109A
    • (1995) Diabetes , vol.44 , Issue.SUPPL. 1
    • Valiquett, T.1    Balagtas, C.2    Whitcomb, R.3
  • 93
    • 4243397821 scopus 로고    scopus 로고
    • Troglitazone monotherapy: Long term efficacy in patients with type 2 diabetes
    • Valiquett T, Huang S, Ghazzi M. Troglitazone monotherapy: long term efficacy in patients with type 2 diabetes [abstract]. Diabetes 1998; 47 Suppl. 1: A 17
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Valiquett, T.1    Huang, S.2    Ghazzi, M.3
  • 94
    • 0013573566 scopus 로고
    • Long-term study of a new oral hypoglycemic agent CS-045 in patients with non-insulin dependent diabetes mellitus
    • Akanuma Y, Kosaka K, Kuzuya T. Long-term study of a new oral hypoglycemic agent CS-045 in patients with non-insulin dependent diabetes mellitus [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 127-49
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 127-149
    • Akanuma, Y.1    Kosaka, K.2    Kuzuya, T.3
  • 95
    • 0002633987 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic agent CS-045 in patients with noninsulin dependent diabetes mellitus poorly controlled by diet alone. A dose-finding study by dose increasing method
    • Akanuma Y, Kosaka K, Knzuya T, et al. Clinical evaluation of a new oral hypoglycemic agent CS-045 in patients with noninsulin dependent diabetes mellitus poorly controlled by diet alone. A dose-finding study by dose increasing method [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 19-37
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 19-37
    • Akanuma, Y.1    Kosaka, K.2    Knzuya, T.3
  • 96
    • 0000247010 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic drug, CS-045, in patients with obese non-insulin dependent diabetes mellitus
    • Ikeda Y, Yamada H, Ohno M. Clinical evaluation of a new oral hypoglycemic drug, CS-045, in patients with obese non-insulin dependent diabetes mellitus [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 179-90
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 179-190
    • Ikeda, Y.1    Yamada, H.2    Ohno, M.3
  • 97
    • 0025941863 scopus 로고
    • Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM
    • Nov
    • Iwamoto Y, Kuzuya T, Matsuda A, et al. Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM. Diabetes Care 1991 Nov; 14: 1083-6
    • (1991) Diabetes Care , vol.14 , pp. 1083-1086
    • Iwamoto, Y.1    Kuzuya, T.2    Matsuda, A.3
  • 98
    • 0030033508 scopus 로고    scopus 로고
    • Effects of troglitazone: A new hypoglycemic agent in patients with NIDDM poorly controlled by diet therapy
    • Feb
    • Iwamoto Y, Kosaka K, Kuzuya T, et al. Effects of troglitazone: a new hypoglycemic agent in patients with NIDDM poorly controlled by diet therapy. Diabetes Care 1996 Feb; 19: 151-6
    • (1996) Diabetes Care , vol.19 , pp. 151-156
    • Iwamoto, Y.1    Kosaka, K.2    Kuzuya, T.3
  • 99
    • 0002633986 scopus 로고
    • An early phase 11 clinical trial of a new oral hypoglycemic drug, CS-045, in patients with non-insulin dependent diabetes mellitus
    • Kuzuya T, Iwamoto Y, Kosaka K, et al. An early phase 11 clinical trial of a new oral hypoglycemic drug, CS-045, in patients with non-insulin dependent diabetes mellitus [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 3-18
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 3-18
    • Kuzuya, T.1    Iwamoto, Y.2    Kosaka, K.3
  • 100
    • 0000123772 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic agent CS-045 in patients with non-insulin dependent diabetes mellitus. Study with 100mg tablet
    • Maruyama H, Hirose H, Shimada A, et al. Clinical evaluation of a new oral hypoglycemic agent CS-045 in patients with non-insulin dependent diabetes mellitus. Study with 100mg tablet [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 205-15
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 205-215
    • Maruyama, H.1    Hirose, H.2    Shimada, A.3
  • 101
    • 0027934465 scopus 로고
    • Effects of a new oral hypoglycaemic agent (CS-045) on metabolic abnormalities and insulin resistance in type 2 diabetes
    • Aug-Sep
    • Mimura K, Umeda F, Hiramatsu S, et al. Effects of a new oral hypoglycaemic agent (CS-045) on metabolic abnormalities and insulin resistance in type 2 diabetes. Diabetic Med 1994 Aug-Sep; 11: 685-91
    • (1994) Diabetic Med , vol.11 , pp. 685-691
    • Mimura, K.1    Umeda, F.2    Hiramatsu, S.3
  • 102
    • 0000735737 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic drug, CS-045, on daily profile of blood glucose in patients with non-insulin dependent diabetes mellitus
    • Nakano K, Yasuda T, Kitagawa Y, et al. Clinical evaluation of a new oral hypoglycemic drug, CS-045, on daily profile of blood glucose in patients with non-insulin dependent diabetes mellitus [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 151-64
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 151-164
    • Nakano, K.1    Yasuda, T.2    Kitagawa, Y.3
  • 103
    • 0028901028 scopus 로고
    • Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives
    • Mar
    • Ogihara T, Rakugi H, Ikegami H, et al. Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives. Am J Hypertens 1995 Mar; 8: 316-20
    • (1995) Am J Hypertens , vol.8 , pp. 316-320
    • Ogihara, T.1    Rakugi, H.2    Ikegami, H.3
  • 104
    • 0000123773 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic drug CS-045 in patients with noninsulin dependent diabetes mellitus accompanying hypertriglyceridemia
    • Yamada N, Akanuma Y, Murase T, et al. Clinical evaluation of a new oral hypoglycemic drug CS-045 in patients with noninsulin dependent diabetes mellitus accompanying hypertriglyceridemia [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 165-78
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 165-178
    • Yamada, N.1    Akanuma, Y.2    Murase, T.3
  • 105
    • 0031979370 scopus 로고    scopus 로고
    • Establishing the dose response curve for metabolic control with troglitazonc, an insulin action enhancer, in type 2 diabetes patients
    • Apr
    • Young MA, Eckland DJA, Eastmond R. Establishing the dose response curve for metabolic control with troglitazonc, an insulin action enhancer, in type 2 diabetes patients. Ann Med 1998 Apr; 30: 206-12
    • (1998) Ann Med , vol.30 , pp. 206-212
    • Young, M.A.1    Eckland, D.J.A.2    Eastmond, R.3
  • 106
    • 0032143711 scopus 로고    scopus 로고
    • Baseline factors affecting the efficacy of troglitazone on plasma glucose in Japanese patients with non-insulin-dependent diabetes mellitus
    • Kuzuya T, Kosaka K, Akanuma Y, et al. Baseline factors affecting the efficacy of troglitazone on plasma glucose in Japanese patients with non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract 1998; 41: 121-9
    • (1998) Diabetes Res Clin Pract , vol.41 , pp. 121-129
    • Kuzuya, T.1    Kosaka, K.2    Akanuma, Y.3
  • 107
    • 0000808860 scopus 로고    scopus 로고
    • Troglitazone plus sulfonylurea combination: Long term efficacy in patients with type 2 diabetes
    • May
    • Draznin B, Driscoll J, Sievers J, et al. Troglitazone plus sulfonylurea combination: long term efficacy in patients with type 2 diabetes [abstract]. Diabetes 1998 May; 47 Suppl. 1: A85
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Draznin, B.1    Driscoll, J.2    Sievers, J.3
  • 108
    • 0002573268 scopus 로고
    • Improved metabolic control by addition of troglitazone to glibenclamide therapy in non-insulin-dependent diabetics
    • Aug
    • Foot EA, Patel J, Williams ZV, et al. Improved metabolic control by addition of troglitazone to glibenclamide therapy in non-insulin-dependent diabetics [abstract]. Diabetologia 1995 Aug; 38 Suppl. 1: A44
    • (1995) Diabetologia , vol.38 , Issue.SUPPL. 1
    • Foot, E.A.1    Patel, J.2    Williams, Z.V.3
  • 109
    • 3543018475 scopus 로고    scopus 로고
    • Troglitazone in combination with sulfonylurea restores glycemic control in patients with type 2 diabetes
    • Horton ES, Whitehous F, Ghazzi MN, et al. Troglitazone in combination with sulfonylurea restores glycemic control in patients with type 2 diabetes. Diabetes Care 1998; 21 (9): 1462-9
    • (1998) Diabetes Care , vol.21 , Issue.9 , pp. 1462-1469
    • Horton, E.S.1    Whitehous, F.2    Ghazzi, M.N.3
  • 110
    • 0002094315 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic agent CS-045 in patients with noninsulin dependent diabetes mellitus poorly controlled by sulfonylureas. A dose-finding study by dose increasing method
    • Akanuma Y, Kosaka K, Kuzuya T, et al. Clinical evaluation of a new oral hypoglycemic agent CS-045 in patients with noninsulin dependent diabetes mellitus poorly controlled by sulfonylureas. A dose-finding study by dose increasing method [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 39-60
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 39-60
    • Akanuma, Y.1    Kosaka, K.2    Kuzuya, T.3
  • 111
    • 0030012267 scopus 로고    scopus 로고
    • Effect of combination therapy of troglitazone and sulphonylureas in patients with type 2 diabetes who were poorly controlled by sulphonylurea therapy alone
    • Apr
    • Iwamoto Y, Kosaka K, Kuzuya T, et al. Effect of combination therapy of troglitazone and sulphonylureas in patients with type 2 diabetes who were poorly controlled by sulphonylurea therapy alone. Diabetic Med 1996 Apr; 13: 365-70
    • (1996) Diabetic Med , vol.13 , pp. 365-370
    • Iwamoto, Y.1    Kosaka, K.2    Kuzuya, T.3
  • 112
    • 0000481291 scopus 로고
    • Clinical evaluation of a new oral hypoglycemic drug CS-045 in patients with non-insulin dependent diabetes mellitus poorly controlled with sulfonylureas. Study with 100mg tablet
    • Seino Y, Ishida H, Kurahachi H, et al. Clinical evaluation of a new oral hypoglycemic drug CS-045 in patients with non-insulin dependent diabetes mellitus poorly controlled with sulfonylureas. Study with 100mg tablet [in Japanese]. Rinsho Iyaku 1993; 9 Suppl. 3: 191-203
    • (1993) Rinsho Iyaku , vol.9 , Issue.SUPPL. 3 , pp. 191-203
    • Seino, Y.1    Ishida, H.2    Kurahachi, H.3
  • 113
    • 0032568310 scopus 로고    scopus 로고
    • Effect of troglitazone in insulin-treated patients with type II diabetes mellitus
    • Troglitazone and Exogenous Insulin Study Group. Mar 26
    • Schwartz S, Raskin P, Fonseca V, et al. Effect of troglitazone in insulin-treated patients with type II diabetes mellitus. Troglitazone and Exogenous Insulin Study Group. N Engl J Med 1998 Mar 26; 338: 861-6
    • (1998) N Engl J Med , vol.338 , pp. 861-866
    • Schwartz, S.1    Raskin, P.2    Fonseca, V.3
  • 114
    • 3543030400 scopus 로고    scopus 로고
    • Troglitazone use in insulin-treated type 2 diabetic patients
    • Buse JB, Gumbiner B, Mathias NP, et al. Troglitazone use in insulin-treated type 2 diabetic patients. Diabetes Care 1998; 21: 1455-61
    • (1998) Diabetes Care , vol.21 , pp. 1455-1461
    • Buse, J.B.1    Gumbiner, B.2    Mathias, N.P.3
  • 115
    • 0000504296 scopus 로고    scopus 로고
    • Long term experience with troglitazone in combination with insulin in type 2 diabetes mellitus
    • May
    • Fonseca V, Graveline J, Nissel J. Long term experience with troglitazone in combination with insulin in type 2 diabetes mellitus [abstract]. Diabetes 1998 May; 47 Suppl. 1: A90
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Fonseca, V.1    Graveline, J.2    Nissel, J.3
  • 116
    • 0013573313 scopus 로고    scopus 로고
    • Clinical evaluation of a new oral hypoglycemic agent CS-045 in combination with insulin
    • Aug
    • Akanuma Y, Kosaka K, Toyoda T, et al. Clinical evaluation of a new oral hypoglycemic agent CS-045 in combination with insulin [abstract]. Diabetologia 1996 Aug; 39 Suppl. 1: A232
    • (1996) Diabetologia , vol.39 , Issue.SUPPL. 1
    • Akanuma, Y.1    Kosaka, K.2    Toyoda, T.3
  • 117
    • 0013573152 scopus 로고
    • A clinical study of a new hypoglycemic agent, troglitazone, in type 2 diabetes patients who are unsatisfactorily-controlled with insulin
    • Fukuda T, Nakano O, Amano M, et al. A clinical study of a new hypoglycemic agent, troglitazone, in type 2 diabetes patients who are unsatisfactorily-controlled with insulin [in Japanese]. Rinsho Iyaku 1995; 11 (10): 2055-62
    • (1995) Rinsho Iyaku , vol.11 , Issue.10 , pp. 2055-2062
    • Fukuda, T.1    Nakano, O.2    Amano, M.3
  • 118
    • 0024341392 scopus 로고
    • Impaired glucose tolerance in the U.S. population
    • Harris MI. Impaired glucose tolerance in the U.S. population. Diabetes Care 1989; 12: 464-74
    • (1989) Diabetes Care , vol.12 , pp. 464-474
    • Harris, M.I.1
  • 119
    • 0029061427 scopus 로고
    • Predicting future diabetes in Latino women with gestational diabetes. Utility of early postpartum glucose tolerance teting
    • Kjos SL, Peters RK, Xiang A, et al. Predicting future diabetes in Latino women with gestational diabetes. Utility of early postpartum glucose tolerance teting. Diabetes 1995; 44: 586-91
    • (1995) Diabetes , vol.44 , pp. 586-591
    • Kjos, S.L.1    Peters, R.K.2    Xiang, A.3
  • 120
    • 0026894511 scopus 로고
    • Ten-year follow-up of Japanese overweight subjects with impaired glucose tolerance: Identification of a diabetes-prone subpopulation
    • Yamada T, Aizawa T, Nagasawa Y, et al. Ten-year follow-up of Japanese overweight subjects with impaired glucose tolerance: identification of a diabetes-prone subpopulation. Intern Med 1992; 31: 877-84
    • (1992) Intern Med , vol.31 , pp. 877-884
    • Yamada, T.1    Aizawa, T.2    Nagasawa, Y.3
  • 121
    • 0031015407 scopus 로고    scopus 로고
    • Impaired glucose tolerance is normalized by treatment with the thiazolidinedione troglitazone
    • Feb
    • Antonucci T, Whitcomb R, McLain R, et al. Impaired glucose tolerance is normalized by treatment with the thiazolidinedione troglitazone. Diabetes Care 1997 Feb; 20: 188-93
    • (1997) Diabetes Care , vol.20 , pp. 188-193
    • Antonucci, T.1    Whitcomb, R.2    McLain, R.3
  • 122
    • 0029911503 scopus 로고    scopus 로고
    • Effect of troglitazone on insulin sensitivity and pancreatic β-cell function in women at high risk for NIDDM
    • Nov
    • Berkowitz K, Peters R, Kjos SL, et al. Effect of troglitazone on insulin sensitivity and pancreatic β-cell function in women at high risk for NIDDM. Diabetes 1996 Nov; 45: 1572-9
    • (1996) Diabetes , vol.45 , pp. 1572-1579
    • Berkowitz, K.1    Peters, R.2    Kjos, S.L.3
  • 123
    • 0001541181 scopus 로고    scopus 로고
    • A 96-week follow-up on cardiac safety in patients with type II diabetes treated with troglitazone
    • May
    • Driscoll J, Ghazzi M, Perez J, et al. A 96-week follow-up on cardiac safety in patients with type II diabetes treated with troglitazone [abstract]. Diabetes 1997 May; 46 Suppl. 1: 149A
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 1
    • Driscoll, J.1    Ghazzi, M.2    Perez, J.3
  • 125
    • 0013624611 scopus 로고    scopus 로고
    • Glaxo Wellcome suspends troglitazone availability
    • Dec 8
    • Glaxo Wellcome suspends troglitazone availability. Marketletter 1997 Dec 8; 24: 21
    • (1997) Marketletter , vol.24 , pp. 21
  • 127
    • 0013599999 scopus 로고    scopus 로고
    • FDA Talk Paper [online]. Available from: URL:http:// www.fda.gov/bbs/topics/ANSWERS/ANS00831.html [Accessed 1997 Nov 7]
  • 128
    • 0003193157 scopus 로고    scopus 로고
    • Liver damage warnings for troglitazone
    • Nov 7
    • Liver damage warnings for troglitazone. Scrip 1997 Nov 7 (2282): 21
    • (1997) Scrip , Issue.2282 , pp. 21
  • 130
    • 0003177238 scopus 로고    scopus 로고
    • Rezulin under renewed fire as label changes
    • Aug 3
    • Rezulin under renewed fire as label changes. Marketletter 1998 Aug 3; 25: 19
    • (1998) Marketletter , vol.25 , pp. 19
  • 131
    • 0000188827 scopus 로고    scopus 로고
    • Liver dysfunction associated with troglitazone (Noscal)
    • Kuramoto K, Shimizu N, Toda G. Liver dysfunction associated with troglitazone (Noscal) [in Japanese]. Rinsho Iyaku 1998; 14 (3): 461-6
    • (1998) Rinsho Iyaku , vol.14 , Issue.3 , pp. 461-466
    • Kuramoto, K.1    Shimizu, N.2    Toda, G.3
  • 132
    • 0032535749 scopus 로고    scopus 로고
    • Fatal hepatotoxicity associated with troglitazone
    • Vella A, de Groen PC, Dinneen SF. Fatal hepatotoxicity associated with troglitazone [letter]. Ann Intern Med 1998; 129 (12): 1080
    • (1998) Ann Intern Med , vol.129 , Issue.12 , pp. 1080
    • Vella, A.1    De Groen, P.C.2    Dinneen, S.F.3
  • 133
    • 0013601272 scopus 로고    scopus 로고
    • Warner-Lambert Rezulin arm in NIH diabetes prevention trial is being retained; Glaxo troglitazone withdrawal in U.K. prompts re-evaluation of U.S. status
    • Dec 8
    • Warner-Lambert Rezulin arm in NIH diabetes prevention trial is being retained; Glaxo troglitazone withdrawal in U.K. prompts re-evaluation of U.S. status. FDC Pink 1997 Dec 8; 59: 5-6
    • (1997) FDC Pink , vol.59 , pp. 5-6
  • 134
    • 0003179638 scopus 로고    scopus 로고
    • Call to ban troglitazone in US
    • Jul
    • Call to ban troglitazone in US. Scrip 1998 Jul 31 (2357): 22
    • (1998) Scrip , vol.31 , Issue.2357 , pp. 22
  • 135
    • 0013600003 scopus 로고    scopus 로고
    • Rezulin monitoring program to he watched closely at FDA Woodcock
    • Jan 4
    • Rezulin monitoring program to he watched closely at FDA Woodcock. Pink Sheet 1999 Jan 4; 61 (1): 14-5
    • (1999) Pink Sheet , vol.61 , Issue.1 , pp. 14-15
  • 136
    • 0032571982 scopus 로고    scopus 로고
    • Potential interaction of troglitazone and cyclosporine
    • May 27
    • Kaplan B, Friedman G, Jacobs M, et al. Potential interaction of troglitazone and cyclosporine. Transplantation 1998 May 27; 65: 1399-400
    • (1998) Transplantation , vol.65 , pp. 1399-1400
    • Kaplan, B.1    Friedman, G.2    Jacobs, M.3
  • 137
    • 0031931104 scopus 로고    scopus 로고
    • Effect of troglitazone on steady-state pharmacokinetics of digoxin
    • Feb
    • Loi C-M, Knowlton PW, Stern R, et al. Effect of troglitazone on steady-state pharmacokinetics of digoxin. J Clin Pharmacol 1998 Feb; 38: 178-83
    • (1998) J Clin Pharmacol , vol.38 , pp. 178-183
    • Loi, C.-M.1    Knowlton, P.W.2    Stern, R.3
  • 138
    • 0032558113 scopus 로고    scopus 로고
    • Effect of troglitazone on cyclosporine whole blood levels
    • Jul 27
    • Burgess SJ, Singer GG, Brennan DC. Effect of troglitazone on cyclosporine whole blood levels. Transplantation 1998 Jul 27; 66: 272
    • (1998) Transplantation , vol.66 , pp. 272
    • Burgess, S.J.1    Singer, G.G.2    Brennan, D.C.3
  • 139
    • 0031768466 scopus 로고    scopus 로고
    • Rezulin (troglitazone) greatly increases cyclosporine metabolism
    • Frantz RP. Rezulin (troglitazone) greatly increases cyclosporine metabolism [letter]. J Heart Lung Transplant 1998; 17 (10): 1037-8
    • (1998) J Heart Lung Transplant , vol.17 , Issue.10 , pp. 1037-1038
    • Frantz, R.P.1
  • 140
    • 0031765483 scopus 로고    scopus 로고
    • Troglitazone, a new antidiabetic agent, decreases cyclosporine level
    • Park MH, Pelegrin D, Haug III MT, et al. Troglitazone, a new antidiabetic agent, decreases cyclosporine level [letter]. J Heart Lung Transplant 1998; 17 (11): 1139-40
    • (1998) J Heart Lung Transplant , vol.17 , Issue.11 , pp. 1139-1140
    • Park, M.H.1    Pelegrin, D.2    Haug M.T. III3
  • 141
    • 4243388818 scopus 로고    scopus 로고
    • Lack of pharmacokinetic interaction between troglitazone and glibenclamide in NIDDM patients
    • Aug
    • Püchler K, Sasahara K, Witte PU, et al. Lack of pharmacokinetic interaction between troglitazone and glibenclamide in NIDDM patients [abstract]. Diabetologia 1996 Aug; 39 Suppl. 1: A232
    • (1996) Diabetologia , vol.39 , Issue.SUPPL. 1
    • Püchler, K.1    Sasahara, K.2    Witte, P.U.3
  • 142
  • 143
    • 0030774765 scopus 로고    scopus 로고
    • Good metabolic and safety profile of troglitazone alone and following alcohol in NIDDM subjects
    • Oct
    • Foot EA, Eastmond R. Good metabolic and safety profile of troglitazone alone and following alcohol in NIDDM subjects. Diabetes Res Clin Pract 1997 Oct; 38: 41-51
    • (1997) Diabetes Res Clin Pract , vol.38 , pp. 41-51
    • Foot, E.A.1    Eastmond, R.2
  • 144
    • 0031951044 scopus 로고    scopus 로고
    • Concomitant administration of cholestyramine influences the absorption of troglitazone
    • Jan
    • Young MA, Lettis S, Eastmond R. Concomitant administration of cholestyramine influences the absorption of troglitazone. Br J Clin Pharmacol 1998 Jan; 45: 37-40
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 37-40
    • Young, M.A.1    Lettis, S.2    Eastmond, R.3
  • 145
    • 0031689117 scopus 로고    scopus 로고
    • Coadministration of acetaminophen and troglitazone: Pharmacokinetics and safety
    • Young MA, Lettis S, Eastmond R. Coadministration of acetaminophen and troglitazone: pharmacokinetics and safety. J Clin Pharmacol 1998; 38: 819-24
    • (1998) J Clin Pharmacol , vol.38 , pp. 819-824
    • Young, M.A.1    Lettis, S.2    Eastmond, R.3
  • 146
    • 0031655412 scopus 로고    scopus 로고
    • Effect or troglitazone on urinary excretion of cortisol and 6-β-hydroxycortisol
    • Koup JR, Anderson G, Loi CM. Effect or troglitazone on urinary excretion of cortisol and 6-β-hydroxycortisol. J Clin Pharmacol 1998; 38: 815-8
    • (1998) J Clin Pharmacol , vol.38 , pp. 815-818
    • Koup, J.R.1    Anderson, G.2    Loi, C.M.3
  • 147
    • 0028937507 scopus 로고
    • Phenytoin causes a rapid increase in 6-β-hydroxycortisol urinary excretion in humans - A putative measure of CYP3A induction
    • Fleishaker JC, Pearson LK, Peters GR. Phenytoin causes a rapid increase in 6-β-hydroxycortisol urinary excretion in humans - a putative measure of CYP3A induction. J Pharm Sci 1995; 84: 292-4
    • (1995) J Pharm Sci , vol.84 , pp. 292-294
    • Fleishaker, J.C.1    Pearson, L.K.2    Peters, G.R.3
  • 148
    • 0024427759 scopus 로고
    • The increase in urinary excretion of 6-beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction
    • Ged C, Rouillon JM, Pichard L, et al. The increase in urinary excretion of 6-beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction. Br J Clin Pharmacol 1989; 28: 373-87
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 373-387
    • Ged, C.1    Rouillon, J.M.2    Pichard, L.3
  • 149
    • 4243351661 scopus 로고    scopus 로고
    • Impact of type II diabetes on employment status and work productivity
    • Lloyd AC, Williams Z, Lacey LA, et al. Impact of type II diabetes on employment status and work productivity [abstract no. 761]. Diabetologia 1996 Suppl. 1: A201
    • (1996) Diabetologia , vol.1 , Issue.SUPPL. 1
    • Lloyd, A.C.1    Williams, Z.2    Lacey, L.A.3
  • 151
    • 1842405437 scopus 로고    scopus 로고
    • Troglitazone for non-insulin-dependent diabetes mellitus
    • May 23
    • Troglitazone for non-insulin-dependent diabetes mellitus. Med Lett Drugs Ther 1997 May 23; 39:49-51
    • (1997) Med Lett Drugs Ther , vol.39 , pp. 49-51
  • 152
    • 0031015396 scopus 로고    scopus 로고
    • Glitazones, a prospect for noninsulin-dependent diabetes
    • Jan 11
    • Petrie J, Small M, Connell J. Glitazones, a prospect for noninsulin-dependent diabetes. Lancet 1997 Jan 11; 349: 70-1
    • (1997) Lancet , vol.349 , pp. 70-71
    • Petrie, J.1    Small, M.2    Connell, J.3
  • 153
    • 4243847130 scopus 로고    scopus 로고
    • Costs of hypoglycaemia in type II diabetics treated with oral hypoglycaemic agents
    • O'Shea SJ, Lloyd AC, Keech ML,et al. Costs of hypoglycaemia in type II diabetics treated with oral hypoglycaemic agents [abstract no. 871]. Diabetologia 1996 Suppl. 1: A230
    • (1996) Diabetologia , Issue.SUPPL. 1
    • O'Shea, S.J.1    Lloyd, A.C.2    Keech, M.L.3
  • 154
    • 0002020756 scopus 로고    scopus 로고
    • Management or non-insulin-dependent diabetes mellitus: Defining the role of melformin
    • Jan
    • Balfour JA, Clissold SP. Management or non-insulin-dependent diabetes mellitus: defining the role of melformin. Dis Manage Health Outcomes 1997 Jan; 1: 49-59
    • (1997) Dis Manage Health Outcomes , vol.1 , pp. 49-59
    • Balfour, J.A.1    Clissold, S.P.2
  • 155
    • 0031909945 scopus 로고    scopus 로고
    • Troglitazone: Review and assessment of its role in the treatment of patients with impaired glucose tolerance and diabetes mellitus
    • Mar
    • Johnson MD, Campbell LK, Campbell RK. Troglitazone: review and assessment of its role in the treatment of patients with impaired glucose tolerance and diabetes mellitus. Ann Pharmacother 1998 Mar; 32: 337-48
    • (1998) Ann Pharmacother , vol.32 , pp. 337-348
    • Johnson, M.D.1    Campbell, L.K.2    Campbell, R.K.3
  • 156
    • 0018867035 scopus 로고
    • Ten-year follow-up of subjects with impaired glucose tolerance: Prevention of diabetes by tolbuamide and diet regulation
    • Sartor G, Schertsten B, Carlstrom S, et al. Ten-year follow-up of subjects with impaired glucose tolerance: prevention of diabetes by tolbuamide and diet regulation. Diabetes 1980; 29 (1): 41-9
    • (1980) Diabetes , vol.29 , Issue.1 , pp. 41-49
    • Sartor, G.1    Schertsten, B.2    Carlstrom, S.3
  • 157
    • 0030877383 scopus 로고    scopus 로고
    • Is troglitazone a real indication for obese subjects with impaired glucose tolerance?
    • Aug
    • Yoshioka K, Yokoo S, Yoshida T, et al. Is troglitazone a real indication for obese subjects with impaired glucose tolerance? [letter]. Diabetes Care 1997 Aug; 20: 1340-1
    • (1997) Diabetes Care , vol.20 , pp. 1340-1341
    • Yoshioka, K.1    Yokoo, S.2    Yoshida, T.3
  • 158
    • 0030877383 scopus 로고    scopus 로고
    • Is troglitazone a real indication for obese subjects with impaired glucose tolerance? Reply
    • Aug
    • Whitcomb R. Is troglitazone a real indication for obese subjects with impaired glucose tolerance? Reply [letter]. Diabetes Care 1997 Aug; 20: 1341
    • (1997) Diabetes Care , vol.20 , pp. 1341
    • Whitcomb, R.1
  • 159
    • 0013573153 scopus 로고    scopus 로고
    • US NIH halts Rezulin trial for diabetes prevention
    • Jun 15
    • US NIH halts Rezulin trial for diabetes prevention. Marketletter 1998 Jun 15; 25: 21
    • (1998) Marketletter , vol.25 , pp. 21


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