Acute effect of troglitazone on glucose metabolism in the absence or presence of insulin in perfused rat hindlimb

Metabolism: Clinical and Experimental

Volumn 46, Issue 6, 1997, Pages 716-721

  Okuno, Akira ^b   Ikeda, Kanako ^b   Shiota, Masakazu ^b   Fujiwara, Toshihiko ^a   Yoshioka, Shinji ^b   Sugano, Tsukasa ^b   Horikoshi, Hiroyoshi ^b  

^a DAIICHI SANKYO CO   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOGEN; INSULIN; LACTIC ACID; PYRUVIC ACID; TROGLITAZONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; GLYCOGEN MUSCLE LEVEL; HINDLIMB; INSULIN SENSITIVITY; MALE; MUSCLE METABOLISM; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION;

EID: 0030996501     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(97)90019-6     Document Type: Article

References (21)

1. Hofmann CA, Colca JR: New oral thiazolidinedione antidiabetic agents act as insulin sensitizer. Diabetes Care 15:1075-1078, 1992
2. Fujiwara T, Yoshioka S, Yoshioka T, et al: Characterization of a new antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats. Diabetes 37:1549-1558, 1988
3. Fujiwara T, Wada M, Fukuda K, et al: Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice. Metabolism 40:1212-1218, 1992
4. Suter SL, Nolan JJ, Wallace P, et al: Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects: Diabetes Care 15:193-203, 1992
5. Iwamoto Y, Kuzuya T, Matsuda A, et al: Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM. Diabetes Care 14:1083-1086, 1991
6. Lee MK, Olefsky JM: Acute effect of troglitazone on insulin action in normal rats. Metabolism 44:1166-1169, 1995
7. Shiota M, Sugano T: Characteristics of rat hindlimbs perfused with erythrocyte- and albumin-free medium. Am J Physiol 251:C78-C84, 1986
8. Ruderman NB, Houghton CRS, Hems R: Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. Biochem J 124:639-651, 1971
9. James DE, Jenkins AR, Kraegen EW: Heterogeneity of insulin action in individual muscle in vivo: Euglycemic clamp studies in rats. Am J Physiol 248:E567-E574, 1985
10. James DE, Burleigh KM, Kraegen EW: In vivo glucose metabolism in individual tissues of the rat. J Biol Chem 261:6366-6374, 1986
11. Gutmann I, Wahlefeld AW: L -(+)-Lactate: Determination with lactate dehydrogenase and NAD, in Bergmeyer HU (ed): Methods of Enzymatic Analysis, vol 3 (ed 2). New York, NY, Academic, 1974, pp 1492-1495
12. Passonneau JW, Lowry OH: Pyruvate: Fluorimetric assay, in Bergmeyer HU (ed): Methods of Enzymatic Analysis, vol 3 (ed 2). New York, NY, Academic, 1974, pp 1452-1456
13. Seifter S, Dayton S, Novic B, et al: The estimation of glycogen with the anthrone reagent. Arch Biochem Biophys 25:191-200, 1950
14. Van Schaftingen E, Leder B, Bartrons R, et al: A kinetic study of pyrophosphate fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose-2,6-bisphosphate. Eur J Biochem 129:191-195, 1982
15. Hue L, Rinder MH: Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues. Biochem J 245:313-324, 1987
16. Williamson DH, Lund P, Krebs HA: The redox state of free nicotinamide-adenine dinucleotide in cytoplasm and mitochondria of rat liver. Biochem J 103:514-527, 1967
17. Randle PJ, Garland PB, Hales CN, et al: The glucose-fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1:785-789, 1963
18. Randle PJ, Kerbey A, Espinal J: Mechanisms decreasing glucose oxidation in diabetes and starvation: Role of lipid fuels and hormones. Diabetes Metab Rev 4:623-638, 1988
19. Garetto LP, Richter EA, Goodman MN, et al: Enhanced muscle glucose metabolism after exercise in the rat: The two phases. Am J Physiol 246:E471-E475, 1984
20. Cartee GD, Young DA, Sleeper MD, et al: Prolonged increase in insulin-stimulated glucose transport in muscle after exercise. Am J Physiol 256:E494-E499, 1989
21. Nolte LA, Gulve EA, Holloszy JO: Epinephrine-induced in vivo muscle glycogen depletion enhances insulin sensitivity of glucose transport. J Appl Physiol 76:2054-2058, 1994