Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 4, 1997, Pages 356-368

  Kawai, Kenji ^a   Kawasaki Tokui, Yoko ^a   Odaka, Tomoyo ^a   Tsuruta, Fujiko ^a   Kazui, Miho ^a   Iwabuchi, Haruo ^a   Nakamura, Takemichi ^a   Kinoshita, Takeshi ^a   Ikeda, Toshihiko ^a   Yoshioka, Takao ^a   Komai, Toru ^a   Nakamura, Kan Ichi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

antidiabetic drug; CAS 97322 87 7; CS 045, disposition, metabolism, pharmacokinetics; troglitazone, metabolites

Indexed keywords

CARBON 14; DRUG METABOLITE; ORAL ANTIDIABETIC AGENT; TROGLITAZONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DOG; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG TISSUE LEVEL; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SEX DIFFERENCE;

ADMINISTRATION, ORAL; ANIMALS; BIOTRANSFORMATION; CHROMANS; CHROMATOGRAPHY, THIN LAYER; DOGS; FECES; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED STRAINS; PROTEIN BINDING; RATS; RATS, INBRED F344; SEX CHARACTERISTICS; THIAZOLES; THIAZOLIDINEDIONES; TISSUE DISTRIBUTION;

EID: 0008861608     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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