Interleukins and cerebral ischaemia

International Review of Neurobiology

Volumn , Issue 40, 1996, Pages 281-298

  Rothwell, Nancy J ^a   Loddick, Sarah A ^a   Stroemer, Paul ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN DERIVATIVE; NEUROPROTECTIVE AGENT;

ANIMAL; BRAIN ISCHEMIA; DISEASE MODEL; HUMAN; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

ANIMALS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKINS; NEUROPROTECTIVE AGENTS;

EID: 8544220450     PISSN: 00747742     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0074-7742(08)60724-2     Document Type: Article

References (90)

1. Albers, G.W., Goldberg, P. & Choi, D.W. (1989).A-methyl-D-aspartate antagonists: ready for clinical trial in brain ischaemia? Ann. Neural. 25, 398-403.
2. Albers, G.W., Goldberg, M.P. & Choi, D.W. (1992) Do.A-methyl-D-aspartate antagonists prevent neuronal injury? Yes. Arch. Neural. 49, 418-420.
3. Allan, S.M., Lalvrence, C.B. & Rothwell, NJ. (1995) Mechanism of action of interleukin-1 (IL1) in excitotoxic brain damage in the rat. Soc. Neurosd. Abst. 21, 37.14.
4. Alnemri, E.S., Fernandes-Alnemri, T. & Litwack, G. (1995) Cloning and expression of four novel isoforms of human interleukin-1β converting enzyme with different apoptotic activities. J. Biol. Chem., 270, 4312-1317.
5. Banati, R.B., GehrmannJ., Schubert, P. & Kreutzberg, G.W. (1993) Cytotoxicity of microgila Glia 7, 111-118.
6. Betz, A.L., Yang, G.-Y. & Davidson, B.L. (1995) Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J. Cereb. Blood Flow Metab. 15,547-551.
7. Bowen, I.D. (1993) Apoptosis or programmed cell death? Cell. Biol. Inter. 17, 365-380.
8. Buttini, M., Sauter, A. & Boddeke, H.W.G.M. (1994) Induction of interleukin-1 beta messenger RNA after focal cerebral ischaemia in the rat. Mol. Brain Res. 23, 126-134.
9. Campbell, I.L., Abraham, C.R., Masliah, E., Kemper, P., Inglis, J.D., Oldstone, M.B.A. & Mucke, L. (1993) Neurological disease induced in transgenic mice by cerebral overexpression ofinterIeukin-6. Proc. NatlAcad. Sei. USA 90, 10061-10065.
10. Chapman, K.T. (1992) Synthesis of a potent, reversible inhibitor interleukin-1β converting enzyme. Inorganic Medic. Chem. Letts. 2, 613-618.
11. Chen, H., Chopp, M. & Bodzin, G. (1992) Neutropenia reduces the volume of cerebral infarction after transient middle cerebral artery occlusion in the rat. Neurosci. Res. Commun. 11, 93-99.
12. Choi, D.W. (1994) Glutamate receptors and the induction of excitotoxic neuronal death. Prog. Brain Res. 100,47-51.
13. Colotta, E, Re, E, Muzio, M., Bertini, B., Polentarutti, N, Sironi, M., Giri, J.G., Dower, S.K., Sims,J.E. & Mantovani, A. (1993) Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-1. Science 261, 472-475.
14. Dietrich, W.D., Busto, R., Halley, M. & Valdes, I. (1990) The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischaemia. J. Neuropath. Exp. Neural. 49, 486-497.
15. Dinarello, C.A. (1991) Interleukin-1 and interleukin-1 antagonist. Blood77, 1627-1652.
16. Dinarello, C.A. (1994) The biological properties of interleukin-1. Em Cylokine Net. 5, 517-531.
17. Dripps, D.J., Brandhuber, BJ., Thompson, R.C. & Einsberg, S.P. (1991) Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor does not initiate IL-1 signal transduction. J. Biol. Chem. 266, 10331-10336.
18. Dubois, C.M., Ruscetti, EW., Palaszynki, E.W., Falk, L.A., OppenheimJJ. & KellerJ.R. (1990) Transforming growth factor is a potent inhibitor of interleukin-1 (IL-1) receptor expression: proposed mechanism of inhibition of IL-1 action. J. Exp. Med. 172, 737-744.
19. Elford, PR., Heng, R., Révész, L. & MacKenzie, A.R. (1995) Reduction of inflammation and pyrexia in the rat by oral administration of SDZ 224-015, an inhibitor of the interleukiri-1β converting enzyme. Br. J. Pharmacol. 115, 601-606.
20. Enari, M., Hug, H. & Nagata, S. (1995) Involvement of ICE and ICE-like protease in Fasmediated apoptosis. Nature 375, 78-81.
21. Ferretti, M., Casini-Raggi, V, Pizarro, T.T., Eisenberg, S.P., Nast, C.C. & Cominelli, E (1994) Neutralisation of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis. J. Clin. Intest. 94,449-453.
22. Fletcher, D.S., Agarwal, L., Chapman, K.T., Chin, J., Egger, L.A., Limjuco, G., Luell, S., Maclntyre, D.E., Peterson, E.P., Thornberry, N.A. & Kotsura, MJ. (1995) A synthetic inhibitor of interleukin-1β converting enzyme prevents endotoxin-induced interleukin-1 β production m ritro and in viio.J. Int. Cyl. Res. 15, 243-248.
23. Frazzini, VI., Wmfree, C.J., Choudhri, H.F., Prestigiacomo, CJ. & Solomon, R.A. (1994) Mud hypothermia and MK-801 have similar but not additive degrees of cerebroprotection in the rat permanent focal ischaemia model. Neurosurgeiy 34, 1040-1045.
24. Fujioka, N., Mukaida, N., Harada, A., Akiyama, M., Kasahara, T., Kuno, K., Ooi, A., Mai, M. & Matsushima, K. (1995) Preparation of specific antibodies against murine IL-lra and the establishment of IL-lra as an endogenous regulator of bacteria-induced fulminant hepatitis in mice. J. Leukocyte Biol. 58, 90-98.
25. Gadient, R.A., Cron, K.C. & Otten, U. (1990) Interleukin-l and tumour necrosis factor-a synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes. Neurosci. Lett. 117, 335-340.
26. Garcia, J.H., Liu, K.-F. & Ho, K.-L. (1995a) Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex. Stroke 26, 636-643.
27. Garcia, J.H., Liu, K.-F. & Relton,J.K. (1995b) Interleukin-1 receptor antagonist decreases the number of necrotic neurones in rats with middle cerebral artery occlusion. Am.J. Pathol. 147, 1477-1486.
28. Ghiara, P., Armellini, D., Scapligliati, G., Nati, S., Nucin, D., Banoli, M., Censini, S., Bill, L., Tagliabue, A., Bossu, P. & Boraschi, D. (1991) Biological role of the IL-1 Type II (IL-l-RII) receptor as defined by a monoclonal antibody.Cytokine 3, 473.
29. Ginsberg, M.D., Globus, M.Y.T., Dietrich, W.D. & Busto, R. (1993) Temperature modulation of ischaemic brain injury -a synthesis of recent advances. In Progress in Brain Research (eds Kogure, K., Hossman, K.A. & Siesjö, B.K.), pp. 13-22 Elsevier, New York.
30. Giulian, D. (1993) Reactive glia as rivals in regulating neuronal survival. Glia 7, 102-110.
31. Giulian, D., Woodward, J., Young, D.G., Krebs, J.F. & Lachman, L.B. (1988) Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularisation.J. Neurosci. 8, 2485-2490.
32. Gordon, N. (1995) Apoptosis (programmed cell death) and other reasons for the elimination of neurones and axons. Brain Derel. 17, 73-77.
33. Greenfeder, S.A., Nunes, P., Kwee, L., Labow, M., Chizzonitc, R.A. &Ju, G. (1995) Molecular cloning and characterisation of a second subunit of the interleukin-1 receptor complex. J. Biol. Chem. 270, 13757-13765.
34. Gutierrez, E.G., Banks, W.A. & Kastin, AJ. (1994) Blood-borne interleukin-1 receptor antagonist crosses the blood brain barrier.J. Neuroimmunol. 55, 153-160.
35. Hopkins, SJ. & Rothwell, SJ. (1995) Gytokines and the nervous system I: expression and recognition. Trends Neuwl. Sei. 18, 83-88.
36. lanotti, E, Kida, S., Weller, R., Buhagier, G. & Hillhouse, E. (1993) Interleukin-l in focal cerebral ischaemia in rats.J. Cereb. Blood Flow Aletab. 13, sl25.
37. Li, P., Alien, H., Banerjee, S., Franklin, S., Herzog, L., Johnstone, C., McDowell, J., Paskind, M., Rodman, L, Salfeld, J, Towne, E., Tracey, D., Wardwell, S., Wei, F.-Y, Wong, W, Kamen, R. & Seshadri, T. (1995) Mice deficient in IL-l-converting enzyme are defective in production of mature IL-l and resistant to endotoxic shock. Cell, 401-411.
38. Lindsberg, PJ., Siren, A.L., Feuerstein, G.Z. & Hallenbeck, J.M. (1991) Postischemic antagonism of neutrophil adherence has an acute therapeutic effect on functional recovery in the deteriorating stroke model in rabbits. J. Cereb. Blood Flow Aletab. 11, s754.
39. Linnick, M.D., Zobrist, R.H. & Hatfield, M.D. (1993) Evidence supporting a role for programmed cell death in focal cerebral ischaemia in rats. Stroke 24, 2001-2009.
40. Lipton, S.A. & Roenberg, P.A. (1994) Excitatory amino acids as a final common pathway for neurological disorders. New Engl. J. Aled. 330, 613-622.
41. Liu, T., McDonnell, P.C., Young, P.R., White, R.F., Siren, A.L., Hallenbeck, J.M., Baron, EG. & Feurestein, G.Z. (1993) Interleukin-1 beta mRNA expression in ischaemic rat cortex. Stroke 24, 1746-1750.
42. Loddick, S.A. & Rothwell, NJ. (1996) Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.J.Cereb.Biood Flow Metab., in press.
43. Luheshi, G., Hopkins, SJ., LeFeuvre, R.A., Dascombe, M.J., Ghiara, P. & Rothwell, NJ. (1993) Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat. Am.J. Phjsiol. 265, E585-E591.
44. Lyons, M.K., Anderson, R.E. & Meyer, F.B. (1991) Corticotropin releasing factor antagonist reduces ischaemic hippocampal neuronal injury. J. Cereb. Blood Flow Aletab. 545, 339-342.
45. Martin, D. & Near, S.L. (1995) Protective effect of the interleukin-1 receptor antagonist (IL-Ira) on experimental allergic encephalomyelitis in rats. J. Neuroimmunol. 61, 241-245.
46. Martin, D., Chinookoswong, N. & Miller, G. (1995) The interleukin-1 receptor antagonist (rhlL-lra) protects against cerebral infarction in a rat model of hypoxia-ischaemia. Exp. Neural. 130, 362-367.
47. McGeer, P.L., Kawamata, T., Walker, D.G., Akiyama, H., Tooyama, I. & McGeer, E.G. (1993) Microglia in degenerative neurological disease. Glia 7, 84-92.
48. Meda, L., Cassatella, M.A., Szendrei, G.I., Otvos, L., Baron, P., Villalba, M., Ferrari, D. & Rossi, F. (1995) Activation ofmicroglial cells by -amyloid protein and interferon-y. Nature 374, 647-650.
49. Meldrum, B.S. (1993) The role of glutamate in epilepsy and other CNS disorders. Neural. 44, S14-23.
50. Meldrum, B. & Garthwaite, J. (1990) Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sei. 11, 379-386.
51. Minami, M., Kuraishi, Y, Yabuuchi, K., Yamazaki, A. & Satoh, M. (1992a) Induction of interleukin-1 mRNA in rat brain after transient forebrain ischaemia. J. Neurochem. 58, 390-392.
52. Minami, M., Yabuuchi, K., Katsumata, S., Tomozawa, Y, Kuraishi, Y & Satoh, M. (1992b) Possible involvement of interleukin-1 in neuronal death after transient forebrain ischaemia. Soc. o/Neurosd. Abst. 18, 425.5.
53. Morikawa, E., Ginsberg, M.D., Dietrich, W.D., Duncan, R.C., Kraydieh, S., Globus, M.Y.T. & Busto, R. (1992) The significance of brain temperature in focal cerebral ischaemia: histopathological consequences of middle cerebral artery occlusion in the rat. J. Cereb. Blood Flow Metab. 12, 380-389
54. O'Neill, L.A.J. (1995) Towards an understanding of the signal transduction pathways for interleukin-1. Biochem. Biophys. Acta. 1266, 31-44.
55. Orrenius, S., McConkey, DJ., Bellomo, G. & Nicotera, P. (1989) Role ofCa in toxic cell killing. Trends Pharmacol. Sei. 10, 281-285.
56. Piani, D., Constam, D.B., Frei, K. & Fontana, A. (1994) Macrophages in the brain: friends or enemies. News P/ysiol. Sei. 9, 80-84.
57. Piani, D., Frei, K., Do, K.Q., Cuénod, M. & Fontana, A. (1991) Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci. Lett. 133, 159-162
58. Prehn,J.H., Backhauss, C. & Krieglstein,J. ( 1993) Transforming growth factor-β1 prevents glutamate neurotoxicity in rat neocortical cultures and protects mouse neocortex from ischaemic injury in viro.J. Cereb. Blood Flow Metab. 13, 521-525.
59. Quirion, R., Araujo, D.M., Lapchak, P.A., Seto, D. & ChabotJ.G. (1991) Growth factors and lymphokines: modulators of cholinergic neuronal activity. Can. J. Neural. Sei. 18, 390-393.
60. Relton, J.K. & Rothwell, NJ. (1992) Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res. Bull. 29, 243-246.
61. Relton, J.K., Strijbos, PJ.L.M., O'Shaugnessy, C.T., Carey, F., Forder, R.A., Tilers, FJ.H. & Rothwell, NJ. (1991) Lipocortin-1 is an endogenous inhibitor of ischaemic damage in the rat brain. J. Exp. Aled. 174, 305-310.
62. Relton,J.K., Martin, D., Thompson, R.C. & Rüssel, D.A. (1996) Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischaemia in the rat. Exp. Neural., in press.
63. Ridenour, T.R., Warner, D.S., Todd, M.M. & McAllister, A.C. (1992) Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischaemia in rats. Stroke 23, 733-738.
64. Rothwell, T.R., Davies, I., Davies, C., Fotheringham, A., Rothwell, NJ. & Stroemer, P. (1995) Involvement of IL-1 in ischaemic brain damage in the mouse. Soc. Neunsci. Abst. 21, 91.3.
65. Rothwell, NJ. & Hopkins, SJ. (1995) Interactions between cytokines and the nervous system II: Actions and mechanisms. Trends Pharmacol. Sei. 18, 130-136.
66. Rothwell, NJ. & Relton,J.K. (1993) Involvement of cytokines in acute neurodegeneration in the CNS. Xeurosci. Behav. Rev: 17,217-227.
67. Rothwell, N.J. & Strijbos, PJ.L.M. (1995) Cytokines in neurodegeneration and repair.Int. J. DevL. Neurosci. 13, 179-185.
68. Shiga, Y, Onodera, H., Kogure, K., Yamasaki, Y, Yashima, Y, Szozuhara, H. & Sendo, F. (1991) Neutrophil as a mediator of ischaemic oedema formation in the brain.Neurosci. Lett. 125,110-112.
69. Shigeno, T., McCulIoch, J., Graham, D.I., Mendelow, A.D. & Teasdale, G.M. (1985) Pure cortical ischaemia versus striatal ischaemia. Surg. Neural. 24, 47-51.
70. Sims, J.E. & Dower, S.K. (1994) Interleukin-1 receptors. Eur. Cytokine. Net. 5, 539-546.
71. Spranger, M., Lindholm, D., Bandtlow, C., Heumann, R., Gnahn, H., Näher-Noe, M. & Thoenn, H. (1990) Regulation or nerve growth factor (NGF) synthesis in the cat central nervous system: comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in rim. Euro. J. Neurosci. 2, 69-76.
72. Strijbos, PJ.L.M., Relton, J.K. & Rothwell, N.J. (1994) Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebral ischaemia or activation of NMDA receptors in the rat brain. Brain Res. 656, 405-408.
73. Strijbos, PJ.L.M. & Rothwell, N.J. (1995) Interleukin-1 attenuates excitatory amino acid induced neurodegeneration in vitro: involvement of nerve growth factor. J. jVeurosci. 15, 3468-3474.
74. Takeshima, R., Kirsch, J.R., Koehler, R.G., Gomall, A.W. & Traystman, RJ. (1991) Effect of neutrophil monoclonal antibody on infarct volume following transient focal cerebral ischaemia in cats. J. Cereb. Blood Flow Metab. 11, s752.
75. Taupin, V, Toulmond, S., Serrano, A., Benavides,J. & Zavala, F. (1993) Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion.J. Neuroimmunol. 42, 177-186.
76. Toulmond, S. & Rothwell, N. (1995a) Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat. Brain Res. 671, 261-266.
77. Toulmond, S. & Rothwell, NJ. (1995b) Time-course of IL-1 receptor antagonist (IL-Ira) expression after brain trauma in the rat. Soc. Neurosci. Abst. 21, 200.2.
78. Toulmond, S., Vige, X., Fage, D. & Benavides,J. (1992) Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurones. Neurosci. Lett. 144,49-52.
79. Toulmond, S., Duval, D., Serrano, A., Scatton, B. & Benavides, J. (1993) Biochemical and histological alterations induced by fluid percussion brain injury in the rat. Brain Res. 620, 24-31.
80. Wang, X., Yue, T.-L., Barone, F.C., White, R.F., Gagnon, R.G. & Feurestein, G.Z. (1994) Concomitant cortical expression of TNF-a and IL-I mRNAs follows early response gene expression in transient focal ischaemia. Mol. Chem. Neuropathol. 23, 103-114.
81. Wang, X.K., Yue, T.L., Young ER., Barone, EC. & Feuerstein, G.Z. (1995) Expression of interleukin-6, c-fos, and zif268 mRNAs in rat ischaemic cortex. J. Cereb. Blood Flow Metab. 15, 166-171.
82. Wiener, C., Gehrmann, J., Lindholm, D., Topper, R., Kreutzberg, G.W. & Hossman, K.A. (1993) Expression of transforming growth factor-l and interleukin-l mRNA in rat brain following transient forebrain ischaemia. Acla Neuropathol. 86, 439-446.
83. Wong, M.-L., Loddick, S.A., Bongiorno, P.B., Gold, P.W., Rothwell, NJ. & Licino, J. (1995) Focal cerebral ischaemia induces CRH mRNA in rat cerebral cortex and amygdala. XeuroReporte, 1785-1788.
84. Woodroofe, M.N., Sarna, G.S., Wawda, M., Hayes, G.M., Loughlin, A.J., Tinker, A. & Cuzner, M.L. ( 1991 ) Detection of interleukin-1 and interleukin-6 in adult rat brain following mechanical injury by in ciro microdialysis: evidence of a role for microglia in cytokine production. J. Immunol. 33, 227-236.
85. Xue, D, Huang, Z.G., Smith, K.E. & Buchan, A.M. (1992) Immediate or delayed mild hypothermia prevents focal cerebral infarction. Brain Res. 587, 66-72.
86. Yabuuchi, K., Minami, M., Katsuata, S., Yamasaki, A. & Satoh, A. (1994) An in situ Hybridisation study of interleukin-1 beta induced by transient forebrain ischaemia in the rat brain. Mol. Brain Res. 26, 135-142.
87. Yamasaki, Y., Matsuo, Y, Matsuura, N., Onodera, H., Itoyama, Y. & Kogurc, K. (1995a) Transient increase of cytokine-induced neutrophil chemoattractant, a member of the interIeukin-8 family, in ischaemic brain areas after focal ischaemia in the rat. Stroke 26, 318-323.
88. Yamasaki, Y, Matsuura, N., Shozuhara, H., Onodera, H., Itoyama, Y. & Kogure, K. (1995b) Interleukin-1 as a pathogenetic mediator of ischaemic brain damage in rats. Stroke 26, 676-681.
89. Yamasaki, Y, Suzuki, T., Yamaya, H., Matsuura, N., Onodera, H. & Kogure, K. (1992) Possible involvement of interleukin-1 in ischaemic brain oedema formation. Neurosci. Lett. 142,45-47.
90. YuanJ., Shaham. Ledoux, S., Ellis, H.M. & Horvitz, H.R. (1993) The C. elegansceü death gene ced-3 encodes a protein similar to mammalian interleukin-1 -converting enzyme. Cell 75, 641-652.