Exploring the leucine-proline binding pocket of the Src SH3 domain using structure-based, split-pool synthesis and affinity-based selection

Journal of the American Chemical Society

Volumn 120, Issue 1, 1998, Pages 30-36

  Morken, James P ^a   Kapoor, Tarun M ^a   Feng, Sibo ^a   Shirai, Fumiyuki ^a   Schreiber, Stuart L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE;

AMINO ACID COMPOSITION; ARTICLE; BINDING AFFINITY; BINDING SITE; DISSOCIATION CONSTANT; DRUG SYNTHESIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

EID: 0032515399     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja972729m     Document Type: Article

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