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Volumn 61, Issue 25, 1996, Pages 8755-8761

Solid-phase combinatorial synthesis of polyisoxazolines: A two-reaction iterative protocol

Author keywords

[No Author keywords available]

Indexed keywords

ISOXAZOLINE DERIVATIVE;

EID: 0030474630     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo961730l     Document Type: Article
Times cited : (52)

References (41)
  • 1
    • 33847466818 scopus 로고    scopus 로고
    • Permanent address:' Institute for Biomédical Research, Teijin Ltd., 4-3-2 Asahigaoka Hino, Tokyo 191, Japan.
    • Permanent address:' Institute for Biomédical Research, Teijin Ltd., 4-3-2 Asahigaoka Hino, Tokyo 191, Japan.
  • 12
    • 2842561522 scopus 로고    scopus 로고
    • (a) Ellman, J. A. Acc. Chem. Res., 1996, 29, 132-43.
    • (1996) Chem. Res. , vol.29 , pp. 132-143
    • Acc, E.J.A.1
  • 28
    • 33847431361 scopus 로고    scopus 로고
    • A polyisoxazole version of this approach is currently under investigation and will be reported in due course
    • A polyisoxazole version of this approach is currently under investigation and will be reported in due course.
  • 29
    • 33847429538 scopus 로고    scopus 로고
    • note
    • Note: a systematic numbering system is employed where the product number is derived from the compound numbers of its component precursors. Thus, referingto Scheme 1, combinatorial components 1, 2, 2, and 6 are employed to construct triisoxazoline 1226 (®1226 when polymer-bound) by the sequence 1 → ®1 + 2 → ®12 + 2 → ®122 + 6 → ®1226 -1226. Solution libraries (see Table 1) are lettered A-U; when polymer-bound, these same libraries are referred to as ®A→ ®U. Finally, oxidative elimination of selenium from ®12 gives olefin ®12a; likewise, oxidative elimination of selenium from library ®A gives library ®Aa. .The symbol ®denotes the resin (styrene/2% divinyl benzene copolymer).
  • 33
    • 0000951871 scopus 로고
    • In a large library, it is quite probable that not all of the targets would be present see: (a)
    • In a large library, it is quite probable that not all of the targets would be present [see: (a) Lowe, G. Chem. Soc. Rev. 1995, 24, 309-317.
    • (1995) Chem. Soc. Rev. , vol.24 , pp. 309-317
    • Lowe, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.