-
1
-
-
0029757751
-
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a proccssivity defect of the reverse transcriptase enzyme
-
Back NKT, Nijhuis M, Keulen W, Boucher CAB, Oude Essink BB, van Kuilenburg ABP, Van Gennip AH, Berkhout B. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a proccssivity defect of the reverse transcriptase enzyme. EMBO J 15: 4040-4049;1996.
-
(1996)
EMBO J
, vol.15
, pp. 4040-4049
-
-
Back, N.K.T.1
Nijhuis, M.2
Keulen, W.3
Boucher, C.A.B.4
Oude Essink, B.B.5
Van Kuilenburg, A.B.P.6
Van Gennip, A.H.7
Berkhout, B.8
-
2
-
-
0030842451
-
Forced evolution of a regulatory RNA helix in the HIV-1 genome
-
Berkhout B, Klaver B, Das AT. Forced evolution of a regulatory RNA helix in the HIV-1 genome. Nucleic Acids Res 25:940-947;1997.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 940-947
-
-
Berkhout, B.1
Klaver, B.2
Das, A.T.3
-
3
-
-
0033081160
-
Proposed alternatives for the use of anti-HIV drugs
-
Berkhout B. Proposed alternatives for the use of anti-HIV drugs. Drug Resist Updates 2:69-70;1999.
-
(1999)
Drug Resist Updates
, vol.2
, pp. 69-70
-
-
Berkhout, B.1
-
4
-
-
0032932711
-
Genetic instability of live-attenuated HIV-1 vaccine strains
-
Berkhout B, Verhoef K, van Wamel JLB, Back B. Genetic instability of live-attenuated HIV-1 vaccine strains. J Virol 73:1138-1145;1999.
-
(1999)
J Virol
, vol.73
, pp. 1138-1145
-
-
Berkhout, B.1
Verhoef, K.2
Van Wamel, J.L.B.3
Back, B.4
-
5
-
-
84878727337
-
Functional analysis of RNA signals in the HIV-1 genome by forced evolution
-
Barciszcwski J, Clark BFC, eds. Dordrecht, Kluwer Academic Publishers, in press
-
Berkhout B, Das AT. Functional analysis of RNA signals in the HIV-1 genome by forced evolution. In: Barciszcwski J, Clark BFC, eds. RNA Biochemistry and Biotechnology. Dordrecht, Kluwer Academic Publishers, in press.
-
RNA Biochemistry and Biotechnology
-
-
Berkhout, B.1
Das, A.T.2
-
6
-
-
0029067808
-
Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity
-
Blain SW, Hendrickson WA, Goff SP. Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity. J Virol 69: 5113-5116;1995.
-
(1995)
J Virol
, vol.69
, pp. 5113-5116
-
-
Blain, S.W.1
Hendrickson, W.A.2
Goff, S.P.3
-
7
-
-
0030065565
-
Resistance of HIV-1 to protease inhibitors: Selection of resistance mutations in the presence and in the absence of the drug
-
Borman A, Paulous S, Clavel F. Resistance of HIV-1 to protease inhibitors: Selection of resistance mutations in the presence and in the absence of the drug. J Gen Virol 77:419-426; 1996.
-
(1996)
J Gen Virol
, vol.77
, pp. 419-426
-
-
Borman, A.1
Paulous, S.2
Clavel, F.3
-
8
-
-
0031849665
-
In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitor
-
Carrillo A, Stewart KD, Sham HL, Norbeck DW, Kohlbrenner WE, Leonard JM, Kempf DJ, Molla A. In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitor. J Virol 72:7532-7541;1998.
-
(1998)
J Virol
, vol.72
, pp. 7532-7541
-
-
Carrillo, A.1
Stewart, K.D.2
Sham, H.L.3
Norbeck, D.W.4
Kohlbrenner, W.E.5
Leonard, J.M.6
Kempf, D.J.7
Molla, A.8
-
9
-
-
0344334073
-
Effects of human immunodeficiency virus type 1 resistance to protease inhibitors on reverse transcriptase processing, activity, and drug sensitivity
-
Carron de la Carrière L, Paulous S, Clavel F, Mammano F. Effects of human immunodeficiency virus type 1 resistance to protease inhibitors on reverse transcriptase processing, activity, and drug sensitivity. J Virol 73:3455-3459; 1999.
-
(1999)
J Virol
, vol.73
, pp. 3455-3459
-
-
Carron De La Carrière, L.1
Paulous, S.2
Clavel, F.3
Mammano, F.4
-
10
-
-
0028952146
-
HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
-
Coffin JM. HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy. Science 267:483-489;1995.
-
(1995)
Science
, vol.267
, pp. 483-489
-
-
Coffin, J.M.1
-
11
-
-
10344263394
-
Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
-
Condra JH, Holder DJ, Schleif WA, Blahy OM, Danovich RM, Gabryelski I.J, Graham DJ, Laird D, Quintero JC, Rhodes A, Robbins HL, Roth E, Shivaprakash M, Yang T, Chodakewitz JA, Deutsch PJ, Leavitt RY, Massari FE, Mellors JW, Squires KE, Steigbigel RT, Teppler H, Emini EA. Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol 70:8270-8276;1996.
-
(1996)
J Virol
, vol.70
, pp. 8270-8276
-
-
Condra, J.H.1
Holder, D.J.2
Schleif, W.A.3
Blahy, O.M.4
Danovich, R.M.5
Gabryelski, I.J.6
Graham, D.J.7
Laird, D.8
Quintero, J.C.9
Rhodes, A.10
Robbins, H.L.11
Roth, E.12
Shivaprakash, M.13
Yang, T.14
Chodakewitz, J.A.15
Deutsch, P.J.16
Leavitt, R.Y.17
Massari, F.E.18
Mellors, J.W.19
Squires, K.E.20
Steigbigel, R.T.21
Teppler, H.22
Emini, E.A.23
more..
-
12
-
-
0031015475
-
Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors
-
Croteau G, Doyon L, Thibeault D, McKercher G, Pilote L, Lamarre D. Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors. J Virol 71:1089-1096;1997.
-
(1997)
J Virol
, vol.71
, pp. 1089-1096
-
-
Croteau, G.1
Doyon, L.2
Thibeault, D.3
McKercher, G.4
Pilote, L.5
Lamarre, D.6
-
13
-
-
0032503234
-
Improved envelope function selected by long-term cultivation of a translation-impaired HIV-1 mutant
-
Das AT, van Dam AP, Klaver B, Berkhout B. Improved envelope function selected by long-term cultivation of a translation-impaired HIV-1 mutant. Virology 244:552-562;1998.
-
(1998)
Virology
, vol.244
, pp. 552-562
-
-
Das, A.T.1
Van Dam, A.P.2
Klaver, B.3
Berkhout, B.4
-
14
-
-
0022321304
-
The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: Biological relevance
-
Domingo E, Martinez-Salas E, Sobrino F, De Latorre JC, Portela A, Ortin J, Lopez-Golindez C, Perez-Brena P, Villa-Nueva N, Najera R, Vandepol S, Steinhauer D, Depolo N, Holland JJ. The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: Biological relevance. Gene 40:1-8;1985.
-
(1985)
Gene
, vol.40
, pp. 1-8
-
-
Domingo, E.1
Martinez-Salas, E.2
Sobrino, F.3
De Latorre, J.C.4
Portela, A.5
Ortin, J.6
Lopez-Golindez, C.7
Perez-Brena, P.8
Villa-Nueva, N.9
Najera, R.10
Vandepol, S.11
Steinhauer, D.12
Depolo, N.13
Holland, J.J.14
-
15
-
-
0029949286
-
Basic concepts in RNA virus evolution
-
Domingo E, Escarmis C, Sevilla N, Moya A, Elena SF, Quer J, Novella IS, Holland JJ. Basic concepts in RNA virus evolution. FASEB J 10: 859-864;1996.
-
(1996)
FASEB J
, vol.10
, pp. 859-864
-
-
Domingo, E.1
Escarmis, C.2
Sevilla, N.3
Moya, A.4
Elena, S.F.5
Quer, J.6
Novella, I.S.7
Holland, J.J.8
-
16
-
-
0030747157
-
RNA virus mutations and fitness for survival
-
Domingo E, Holland JJ. RNA virus mutations and fitness for survival. Annu Rev Microbiol 51:151-178;1997.
-
(1997)
Annu Rev Microbiol
, vol.51
, pp. 151-178
-
-
Domingo, E.1
Holland, J.J.2
-
17
-
-
0029899093
-
Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors
-
Doyon L, Croteau G, Thibeault D, Poulin F, Pilote L, Lamarre D. Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors. J Virol 70:3763-3769;1996.
-
(1996)
J Virol
, vol.70
, pp. 3763-3769
-
-
Doyon, L.1
Croteau, G.2
Thibeault, D.3
Poulin, F.4
Pilote, L.5
Lamarre, D.6
-
18
-
-
0031748806
-
Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors
-
Doyon L, Payant C, Brakier-Gingras E, Lamarre D. Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors. J Virol 72: 6146-6150;1998.
-
(1998)
J Virol
, vol.72
, pp. 6146-6150
-
-
Doyon, L.1
Payant, C.2
Brakier-Gingras, E.3
Lamarre, D.4
-
19
-
-
0031950370
-
Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (norvir) monotherapy
-
Eastman PS, Mittler J, Kelso R, Gee C, Boyer E, Kolberg J, Urdea M, Leonard JM, Norbeck DW, Mo H, Markowitz M. Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (norvir) monotherapy. J Virol 72:5154-5164; 1998.
-
(1998)
J Virol
, vol.72
, pp. 5154-5164
-
-
Eastman, P.S.1
Mittler, J.2
Kelso, R.3
Gee, C.4
Boyer, E.5
Kolberg, J.6
Urdea, M.7
Leonard, J.M.8
Norbeck, D.W.9
Mo, H.10
Markowitz, M.11
-
21
-
-
0029745634
-
A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation
-
Fan N, Rank KB, Slade DE, Poppe SM, Evans DB, Kopta LA, Olmsted RA, Thomas RC, Tarpley WG, Sharma SK. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry 35:9737-9745;1996.
-
(1996)
Biochemistry
, vol.35
, pp. 9737-9745
-
-
Fan, N.1
Rank, K.B.2
Slade, D.E.3
Poppe, S.M.4
Evans, D.B.5
Kopta, L.A.6
Olmsted, R.A.7
Thomas, R.C.8
Tarpley, W.G.9
Sharma, S.K.10
-
22
-
-
0033521911
-
Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes
-
Gao F, Bailes E, Robertson DE, Chen Y, Rodenburg CM, Michael SF, Cummins LB, Arthur LO, Peeters M, Shaw GM, Sharp PM, Hahn BH. Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. Nature 397:436-441;1999.
-
(1999)
Nature
, vol.397
, pp. 436-441
-
-
Gao, F.1
Bailes, E.2
Robertson, D.E.3
Chen, Y.4
Rodenburg, C.M.5
Michael, S.F.6
Cummins, L.B.7
Arthur, L.O.8
Peeters, M.9
Shaw, G.M.10
Sharp, P.M.11
Hahn, B.H.12
-
23
-
-
0030926277
-
Broad spectrum of in vivo fitness of human immunodeficiency virus type 1 subpopulations differing at reverse transcriptase codons 41 and 215
-
Goudsmit J, de Ronde A, de Rooij E, de Boer RJ. Broad spectrum of in vivo fitness of human immunodeficiency virus type 1 subpopulations differing at reverse transcriptase codons 41 and 215. J Virol 71:4479-4484;1998.
-
(1998)
J Virol
, vol.71
, pp. 4479-4484
-
-
Goudsmit, J.1
De Ronde, A.2
De Rooij, E.3
De Boer, R.J.4
-
24
-
-
0031958266
-
Relative replication fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro
-
Harrigan PR, Bloor S, Larder BA. Relative replication fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro. J Virol 72:3773-3778;1998.
-
(1998)
J Virol
, vol.72
, pp. 3773-3778
-
-
Harrigan, P.R.1
Bloor, S.2
Larder, B.A.3
-
25
-
-
0028014288
-
Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor
-
Ho DD, Toyoshima T, Mo H, Kempf DJ, Norbeck D, Chen C-M, Wideburg NE, Burt SK, Erickson JW, King MK. Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor. J Virol 68:2016-2020; 1994.
-
(1994)
J Virol
, vol.68
, pp. 2016-2020
-
-
Ho, D.D.1
Toyoshima, T.2
Mo, H.3
Kempf, D.J.4
Norbeck, D.5
Chen, C.-M.6
Wideburg, N.E.7
Burt, S.K.8
Erickson, J.W.9
King, M.K.10
-
26
-
-
0031583997
-
Structure of a G48H mutant of HIV-1 protease explains how glycinc-48 replacements produce mutants resistant to inhibitor drugs
-
Hong L, Zhang X-J, Foundling S, Hartsuck JA, Tang J. Structure of a G48H mutant of HIV-1 protease explains how glycinc-48 replacements produce mutants resistant to inhibitor drugs. FEBS Lett 420:11-16;1997.
-
(1997)
FEBS Lett
, vol.420
, pp. 11-16
-
-
Hong, L.1
Zhang, X.-J.2
Foundling, S.3
Hartsuck, J.A.4
Tang, J.5
-
27
-
-
0030772853
-
Higher fidelity of RNA-dependent DNA mispair extension by M 184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1
-
Hsu M, Inouye P, Rezende L, Richard N, Li Z, Prasad VR, Wainberg MA. Higher fidelity of RNA-dependent DNA mispair extension by M 184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. Nucleic Acids Res 25:4532-4536; 1997.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4532-4536
-
-
Hsu, M.1
Inouye, P.2
Rezende, L.3
Richard, N.4
Li, Z.5
Prasad, V.R.6
Wainberg, M.A.7
-
28
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang H, Chopra R, Verdine GL, Harrison SC. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance. Science 282:1669-1675;1998.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
29
-
-
0027318776
-
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA
-
Jacobo-Molina A, Ding J, Nanni RG, Clark ADC Jr, Lu X, Tantillo C, Williams RL, Kamer G, Ferris AL, Clark P, Hizi A, Hughes SH, Arnold E. Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA. Proc Natl Acad Sci USA 90:6320-6324;1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6320-6324
-
-
Jacobo-Molina, A.1
Ding, J.2
Nanni, R.G.3
Clark A.D.C., Jr.4
Lu, X.5
Tantillo, C.6
Williams, R.L.7
Kamer, G.8
Ferris, A.L.9
Clark, P.10
Hizi, A.11
Hughes, S.H.12
Arnold, E.13
-
30
-
-
0028286025
-
Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease
-
Kaplan A, Michael S, Wehbie R, Knigge M, Paul D, Everitt L, Kempf D, Norbeck D, Erickson J, Swanstrom R. Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease. Proc Natl Acad Sci USA 91:5597-5601;1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5597-5601
-
-
Kaplan, A.1
Michael, S.2
Wehbie, R.3
Knigge, M.4
Paul, D.5
Everitt, L.6
Kempf, D.7
Norbeck, D.8
Erickson, J.9
Swanstrom, R.10
-
31
-
-
0029885139
-
Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins
-
Keulen W, Boucher C, Berkhout B. Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins. Antiviral Res 31:45-57;1996.
-
(1996)
Antiviral Res
, vol.31
, pp. 45-57
-
-
Keulen, W.1
Boucher, C.2
Berkhout, B.3
-
32
-
-
0030896362
-
Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of the human immunodeficiency virus type 1 reverse transcriptase
-
Keulen W, Back NKT, van Wijk A, Boucher CAB, Berkhout B. Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of the human immunodeficiency virus type 1 reverse transcriptase. J Virol 71:3346-3350;1997.
-
(1997)
J Virol
, vol.71
, pp. 3346-3350
-
-
Keulen, W.1
Back, N.K.T.2
Van Wijk, A.3
Boucher, C.A.B.4
Berkhout, B.5
-
33
-
-
0028304885
-
Evolution of a disrupted TAR RNA hairpin structure in the HIV-1 virus
-
Klaver B, Berkhout B. Evolution of a disrupted TAR RNA hairpin structure in the HIV-1 virus. EMBO J 13:2650-2659;1994.
-
(1994)
EMBO J
, vol.13
, pp. 2650-2659
-
-
Klaver, B.1
Berkhout, B.2
-
34
-
-
0026693137
-
Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
Kohlstaedt LA, Wang J, Friedman JM, Rice PA, Steitz TA. Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256:1783-1790; 1992.
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
Rice, P.A.4
Steitz, T.A.5
-
36
-
-
0031949856
-
Compensatory point mutations in the human immunodeficiency virus type 1 Gag region that are distal from deletion mutations in the dimerization initiation site can restore viral replication
-
Liang C, Rong L, Laughrea M, Kleiman L, Wainberg MA. Compensatory point mutations in the human immunodeficiency virus type 1 Gag region that are distal from deletion mutations in the dimerization initiation site can restore viral replication. J Virol 72:6629-6636; 1998.
-
(1998)
J Virol
, vol.72
, pp. 6629-6636
-
-
Liang, C.1
Rong, L.2
Laughrea, M.3
Kleiman, L.4
Wainberg, M.A.5
-
37
-
-
0024406911
-
Complete mutagenesis of the HIV-1 protease
-
Loeb DD, Swanstrom R, Everitt L, Manchester M, Stamper SE, Hutchison CA III. Complete mutagenesis of the HIV-1 protease. Nature 340:397-400;1989.
-
(1989)
Nature
, vol.340
, pp. 397-400
-
-
Loeb, D.D.1
Swanstrom, R.2
Everitt, L.3
Manchester, M.4
Stamper, S.E.5
Hutchison C.A. III6
-
38
-
-
0031846317
-
Resistanceassociated loss of viral fitness in human immunodeficiency virus type 1: Phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patients
-
Mammano F, Petit C, Clavel F. Resistanceassociated loss of viral fitness in human immunodeficiency virus type 1: Phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patients. J Virol 72:7632-7637;1998.
-
(1998)
J Virol
, vol.72
, pp. 7632-7637
-
-
Mammano, F.1
Petit, C.2
Clavel, F.3
-
39
-
-
0028854676
-
Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor
-
Markowitz M, Mo H, Kempf DJ, Norbeek DW, Bhat TN, Erickson JW, Ho DD. Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor. J Virol 69:701-706;1995.
-
(1995)
J Virol
, vol.69
, pp. 701-706
-
-
Markowitz, M.1
Mo, H.2
Kempf, D.J.3
Norbeek, D.W.4
Bhat, T.N.5
Erickson, J.W.6
Ho, D.D.7
-
40
-
-
15444377672
-
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
-
Molla A, Korneyeva M, Gao Q, Vasanonda S, Schipper PJ, Mo HM, Markowitz M, Chernyavskiy T, Niu P, Lyons N, Hsu A, Granneman GR, Ho DD, Boucher CAB, Leonard JM, Norbeck DW, Kempf DJ. Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nature Med 2:760-766; 1996.
-
(1996)
Nature Med
, vol.2
, pp. 760-766
-
-
Molla, A.1
Korneyeva, M.2
Gao, Q.3
Vasanonda, S.4
Schipper, P.J.5
Mo, H.M.6
Markowitz, M.7
Chernyavskiy, T.8
Niu, P.9
Lyons, N.10
Hsu, A.11
Granneman, G.R.12
Ho, D.D.13
Boucher, C.A.B.14
Leonard, J.M.15
Norbeck, D.W.16
Kempf, D.J.17
-
41
-
-
0003518435
-
Human retroviruses and aids. A compilation and analysis of nucleic acid and amino acid sequences
-
Anonymous. Los Alamos, Los Alamos National Laboratory
-
Myers G, Korber B, Hahn BH, Jeang KT, Mellors JH, McCutchan FE, Henderson LE, Pavlakis GN. Human retroviruses and AIDS. A compilation and analysis of nucleic acid and amino acid sequences. In: Anonymous. Theoretical Biology and Biophysics Group. Los Alamos, Los Alamos National Laboratory, 1995.
-
(1995)
Theoretical Biology and Biophysics Group
-
-
Myers, G.1
Korber, B.2
Hahn, B.H.3
Jeang, K.T.4
Mellors, J.H.5
McCutchan, F.E.6
Henderson, L.E.7
Pavlakis, G.N.8
-
42
-
-
0029897567
-
(Alkylamino)piperidine bis(heteroaryl) piperizine analogs and potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1 IIIB with reduced replication phenotypes
-
Olmsted RA, Slade DE, Kopta LA, Poppe SM, Poel TJ, Newport SW, Rank KB, Biles C, Morge RA, Dueweke TJ, Yagi Y, Romero DL, Thomas RC, Sharma SK, Tarpley WG. (Alkylamino)piperidine bis(heteroaryl) piperizine analogs and potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1 IIIB with reduced replication phenotypes. J Virol 70:3698-3705; 1996.
-
(1996)
J Virol
, vol.70
, pp. 3698-3705
-
-
Olmsted, R.A.1
Slade, D.E.2
Kopta, L.A.3
Poppe, S.M.4
Poel, T.J.5
Newport, S.W.6
Rank, K.B.7
Biles, C.8
Morge, R.A.9
Dueweke, T.J.10
Yagi, Y.11
Romero, D.L.12
Thomas, R.C.13
Sharma, S.K.14
Tarpley, W.G.15
-
43
-
-
0030791104
-
Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase
-
Oude Essink BB, Back NKT, Berkhout B. Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase. Nucleic Acids Res 25:3212-3217;1997.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3212-3217
-
-
Oude Essink, B.B.1
Back, N.K.T.2
Berkhout, B.3
-
44
-
-
0028949246
-
Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor
-
Patick AK, Rose R, Greytok J, Bechtold CM, Hermsmeier PT, Chen PT, Barrish JC, Zahler R, Colonno RJ, Lin PF. Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor. J Virol 69:2148-2152;1995.
-
(1995)
J Virol
, vol.69
, pp. 2148-2152
-
-
Patick, A.K.1
Rose, R.2
Greytok, J.3
Bechtold, C.M.4
Hermsmeier, P.T.5
Chen, P.T.6
Barrish, J.C.7
Zahler, R.8
Colonno, R.J.9
Lin, P.F.10
-
45
-
-
0031897968
-
The impact of multidideoxynucleoside resistance-conferring mutations in human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and error specificity
-
Rezende LF, Curr K, Ueno T, Mitsuya H, Prasad VK. The impact of multidideoxynucleoside resistance-conferring mutations in human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and error specificity. J Virol 72:2890-2895;1998.
-
(1998)
J Virol
, vol.72
, pp. 2890-2895
-
-
Rezende, L.F.1
Curr, K.2
Ueno, T.3
Mitsuya, H.4
Prasad, V.K.5
-
46
-
-
0029563229
-
Development of drug resistance to HIV-1 protease inhibitors
-
Ridky T, Leis J. Development of drug resistance to HIV-1 protease inhibitors. J Biol Chem 270:29621-29623;1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 29621-29623
-
-
Ridky, T.1
Leis, J.2
-
47
-
-
0032578505
-
Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate
-
Ridky TW, Kikonyogo A, Leis J. Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate. Biochemistry 37:13835-13845;1998.
-
(1998)
Biochemistry
, vol.37
, pp. 13835-13845
-
-
Ridky, T.W.1
Kikonyogo, A.2
Leis, J.3
-
48
-
-
0029869305
-
Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors
-
Rose RE, Gong Y-F, Greytok JA, Bechtold CM, Terry BJ, Robinson BS, Alan M, Colonno RJ, Lin PF: Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors. Proc Natl Acad Sci USA 93:1648-1653; 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1648-1653
-
-
Rose, R.E.1
Gong, Y.-F.2
Greytok, J.A.3
Bechtold, C.M.4
Terry, B.J.5
Robinson, B.S.6
Alan, M.7
Colonno, R.J.8
Lin, P.F.9
-
49
-
-
0028241446
-
Mutation in HIV-1 reverse transcriptase and protease associated with drug resistance
-
Schinazi R, Larder BA, Mellors J. Mutation in HIV-1 reverse transcriptase and protease associated with drug resistance. Int Antiviral News 5:72-75;1994.
-
(1994)
Int Antiviral News
, vol.5
, pp. 72-75
-
-
Schinazi, R.1
Larder, B.A.2
Mellors, J.3
-
50
-
-
0027409698
-
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides
-
Schinazi RF, Lloyd RM Jr, Nguyen M-H, Cannon DL, McMillan A, Ilksoy N, Chu CK, Liotta DC, Bazmi HZ, Mellors JW. Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides. Antimicrob Agents Chemother 37:875-881;1993.
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 875-881
-
-
Schinazi, R.F.1
Lloyd R.M., Jr.2
Nguyen, M.-H.3
Cannon, D.L.4
McMillan, A.5
Ilksoy, N.6
Chu, C.K.7
Liotta, D.C.8
Bazmi, H.Z.9
Mellors, J.W.10
-
51
-
-
0029861757
-
Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity
-
Taddeo B, Carlini F, Verani P, Engelman A. Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity. J Virol 70:8277-8284;1996.
-
(1996)
J Virol
, vol.70
, pp. 8277-8284
-
-
Taddeo, B.1
Carlini, F.2
Verani, P.3
Engelman, A.4
-
52
-
-
0028172345
-
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase
-
Tantillo C, Ding J, Jacobo-Molina A, Nanni RG, Boyer PL, Hughes SH, Pauwels R, Andries K, Janssen PAJ, Arnold E. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. J Mol Biol 243: 369-387;1994.
-
(1994)
J Mol Biol
, vol.243
, pp. 369-387
-
-
Tantillo, C.1
Ding, J.2
Jacobo-Molina, A.3
Nanni, R.G.4
Boyer, P.L.5
Hughes, S.H.6
Pauwels, R.7
Andries, K.8
Janssen, P.A.J.9
Arnold, E.10
-
53
-
-
0032902876
-
Evolution of the HIV-1 LTR promoter by conversion of an NF-ΚB enhancer element into a GABP binding site
-
Verhoef K, Sanders RW, Fontaine V, Kitajima S, Berkhout B. Evolution of the HIV-1 LTR promoter by conversion of an NF-ΚB enhancer element into a GABP binding site. J Virol 73: 1331-1340;1999.
-
(1999)
J Virol
, vol.73
, pp. 1331-1340
-
-
Verhoef, K.1
Sanders, R.W.2
Fontaine, V.3
Kitajima, S.4
Berkhout, B.5
-
54
-
-
0032976394
-
A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus
-
Verhoef K, Berkhout B. A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus. J Virol 73: 2781-2789;1999.
-
(1999)
J Virol
, vol.73
, pp. 2781-2789
-
-
Verhoef, K.1
Berkhout, B.2
-
55
-
-
13344294407
-
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase
-
Wainberg MA, Drosopoulos WC, Salomon H, Hsu M, Borkow G, Parniak MA, Gu Z, Song Q, Manne J, Islam S, Castriota G, Prasad VR. Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Science 271: 1282-1285;1996.
-
(1996)
Science
, vol.271
, pp. 1282-1285
-
-
Wainberg, M.A.1
Drosopoulos, W.C.2
Salomon, H.3
Hsu, M.4
Borkow, G.5
Parniak, M.A.6
Gu, Z.7
Song, Q.8
Manne, J.9
Islam, S.10
Castriota, G.11
Prasad, V.R.12
-
56
-
-
0024381645
-
Functional interaction of constant and variable domains of human immunodeficiency virus type gp120
-
Willey RL, Ross EK, Buckler-White AJ, Theodore TS, Martin MA. Functional interaction of constant and variable domains of human immunodeficiency virus type gp120. J Virol 63: 3595-3600;1989.
-
(1989)
J Virol
, vol.63
, pp. 3595-3600
-
-
Willey, R.L.1
Ross, E.K.2
Buckler-White, A.J.3
Theodore, T.S.4
Martin, M.A.5
-
57
-
-
0031949563
-
Human immunodeficiency virus type 1 protease genotypes and in vitro protease inhibitors susceptibilities of isolates from individuals who were switched to other protease inhibitors after long-term saquinavir treatment
-
Winters MA, Schapiro JM, Lawrence J, Merigan TC. Human immunodeficiency virus type 1 protease genotypes and in vitro protease inhibitors susceptibilities of isolates from individuals who were switched to other protease inhibitors after long-term saquinavir treatment. J Virol 72:5303-5306;1998.
-
(1998)
J Virol
, vol.72
, pp. 5303-5306
-
-
Winters, M.A.1
Schapiro, J.M.2
Lawrence, J.3
Merigan, T.C.4
-
58
-
-
0031946007
-
Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo
-
Zennou V, Mammano F, Paulous S, Mathez D, Clavel F. Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo. J Virol 72:3300-3306;1998.
-
(1998)
J Virol
, vol.72
, pp. 3300-3306
-
-
Zennou, V.1
Mammano, F.2
Paulous, S.3
Mathez, D.4
Clavel, F.5
-
59
-
-
0030769354
-
Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites
-
Zhang Y, Imamichi H, Imamichi T, Lane H, Falloon J, Vasudevachari M, Salzman N. Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites. J Virol 71:6662-6670;1997.
-
(1997)
J Virol
, vol.71
, pp. 6662-6670
-
-
Zhang, Y.1
Imamichi, H.2
Imamichi, T.3
Lane, H.4
Falloon, J.5
Vasudevachari, M.6
Salzman, N.7
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