Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-κB enhancer element into a GABP binding site

Journal of Virology

Volumn 73, Issue 2, 1999, Pages 1331-1340

  Verhoef, Koen ^a   Sanders, Rogier W ^a   Fontaine, Veronique ^a   Kitajima, Shigetaka ^b   Berkhout, Ben ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; CELL STIMULATION; ENHANCER REGION; EVOLUTION; GENE EXPRESSION; GENE SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; PRIORITY JOURNAL; PROMOTER REGION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EID: 0032902876     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.2.1331-1340.1999     Document Type: Article

References (61)

1. Alcami, J., T. Lain de Lera, L. Folgueira, M. A. Pedraza, J. M. Jacque, F. Bachelerie, A. R. Noriega, R. T. Hay, D. Harrich, R. B. Gaynor, J.-L. Virelizier, and F. Arenzana-Seisdedos. 1995. Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in Wood CD4 T lymphocytes. EMBO J. 14:1552-1560.
2. Back, N. K. T., M. Nijhuis, W. Keulen, C. A. B. Boucher, B. B. Oude Essink, A. B. P. van Kuilenburg, A. H. Van Gennip, and B. Berkhout. 1996. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J. 15:4040-4049.
3. Baldwin, A. S., K. P. LeClair, S. Harinder, and P. A. Sharp. 1990. A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglohulin genes. Mol. Cell. Biol. 10:1406-1414.
4. Bassuk, A. G., R. T. Anandappa, and J. M. Leiden. 1997. Physical interactions between Ets and NF-κB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency enhancer in T cells. J. Virol. 71:3563-3573.
5. Batchelor, A. H., D. E. Piper, C. Charles de la Brousse, S. L. McKnight, and C. Wolberger. 1998. The structure of GABPα/β: an ETS domain-ankyrin repeat heterodimer bound to DNA. Science 279:1037-1041.
6. Bell, B., and I. Sadowski. 1996. Ras-responsiveness of the HIV-1 LTR requires RBF-1 and RBF-2 binding sites. Oncogene 13:2687-2697.
7. Berkhout, B., and K. T. Jeang. 1992. Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat. J. Virol. 66:139-149.
8. Berkhout, B., R. H. Silverman, and K. T. Jeang. 1989. Tat trans-activates the human immunodeficiency virus through a nascent RNA target. Cell 59:273-282.
9. Bruder, J. T., G. Heidecker, T. Tan, J. C. Weske, D. Derse, and U. R. Rapp. 1993. Oncogene activation of the HIV-LTR-driven expression via the NF-κB binding sites. Nucleic Acids Res. 21:5229-5234.
10. Carvalho, M., M. Kirkland, and D. Derse. 1993. Protein interactions with DNA elements in variant equine infectious anemia virus enhancers and their impact on transcriptional activity. J. Virol. 67:6586-6595.
11. Chen, B. K., M. B. Feinberg, and D. Baltimore. 1997. The κB sites in the human immunodeficiency virus type I long terminal repeat enhance virus replication yet are not absolutely required for viral growth. J. Virol. 71:5495-5504.
12. Das, A. T., B. Klaver, B. I. F. Klasens, J. L. B. van Wamel, and B. Berkhout. 1997. A conserved hairpin motif in the R-U5 region of the human immunodeficiency virus type 1 RNA genome is essential for replication. J. Virol. 71:2346-2356.
13. Das, A. T., A. P. van Dam, B. Klaver, and B. Berkhout. 1998. Improved envelope function selected by long-term cultivation of a translation-impaired HIV-1 mutant. Virology 244:552-562.
14. Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
15. Dingwall, C., I. Ernberg, M. J. Gait, S. M. Green, S. Heaphy, J. Karn, A. D. Lowe, M. Singh, M. A. Skinner, and R. Valerio. 1989. Human immunodeficiency virus 1 Tat protein binds trans-activating-rcsponsive region (TAR) RNA in vitro. Proc. Natl. Acad. Sci. USA 86:6925-6929.
16. Dittmar, M. T., G. Simmons, S. Hibbitts. M. O'Hare, S. Louisrirotchanakul, S. Beddows, J. Weber, P. R. Clapham, and R. A. Weiss. 1997. Langerhans cell tropism of human immunodeficiency virus type 1 subtype A through F isolates derived from different transmission groups. J. Virol. 71:8008-8013.
17. Flory, E., A. Hofmeyer, U. Smola, U. R. Rapp, and J. T. Bruder. 1996. Raf-1 kinase targets GA-binding protein in transcriptional regulation of the human immunodeficiency virus type 1 promoter. J. Virol. 70:2260-2268.
18. Gao, F., D. L, Robertson, C. D. Carruthers, S. G. Morrison, B. Jian, Y. Chen, F. Barre-Sinoussi, M. Girard, A. Srinivasan, A. G. Abimiku, G. M. Shaw, P. M. Sharp, and B. H. Hahn. 1998. A comprehensive panel of near-full length clones and reference sequences for non-subtype B isolates of human immunodeficiency virus type 1. J. Virol. 72:5680-5698.
19. Gegonne, A., R. Bosselut, R.-A. Bailly, and J. Ghysdael. 1993. Synergistic activation of the HTLV-1 LTR ets-responsive region by transcription factors Ets1 and Sp1. EMBO J. 12:1169-1178.
20. Harrigan. P. R., S. Bloor, and B. A. Larder. 1998. Relative replication fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro. J. Virol. 72:3773-3778.
21. Hodge, D. R., L, Robinson, D. Watson, J. Lautenberger, X. K. Zhang, M. Venanzoni, and A. Seth. 1996. Interaction of Ets-1 and ERGB/Fli-1 proteins with DNA is modulated by spacing between multiple sites as well as phosphorylation. Oncogene 12:11-18.
22. Holzmeister, J., B. Ludewig, G. Pauli, and D. Simon. 1993. Sequence specific binding of the transcription factor c-etsl to the human immunodeficiency virus type I long terminal repeat. Biochem. Biophys. Res. Commun. 197: 1229-1233.
23. Israël, A., O. Le Bail, D. Hatat, J. Piette, M. Kieran, F. Logeat, D. Wallach, M. Fellous, and P. Kourilsky. 1989. TNF stimulates expression of mouse MHC class I genes by inducing an NF-κB-like enhancer binding activity which displaces constitutive factors. EMBO J. 8:3793-3800.
24. Janknecht, R., and A. Nordheim. 1993. Gene regulation by Ets proteins. Biochim. Biophys. Acta 1155:346-356.
25. Jeang, K.-T. 1998. Tat, Tat-associated kinase, and transcription. J. Biomed. Sci. 5:24-27.
26. John, S., R. B. Reeves, J.-X. Lin, R. Child, J. M. Leiden, C. B. Thompson, and W. J. Leonard. 1995. Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-κB family proteins. Mol. Cell. Biol. 15:1786-1796.
27. Jones, K. A. 1997. Taking a new TAK on Tat transactivation. Genes Dev. 11:2593-2599.
28. Kamura, T., H. Handa, N. Hamasaki, and S. Kitajima. 1997. Characterization of the human thrombopoietin gene promoter. J. Biol. Chem. 272:11361-11368.
29. Kingsman, S. M., and A. Kingsman. 1996. The regulation of human immunodeficiency virus type 1 gene expression. Eur. J. Biochem. 240:491-507.
30. Klaver, B., and B. Berkhout. 1994. Comparison of 5′ and 3′ long terminal repeat promoter function in human immunodeficiency virus. J. Virol. 68: 3830-3840.
31. Koken, S. E. C., A. E. Greijer, K. Verhoef, J. van Wamel, A. G. Bukrinskaya, and B. Berkhout. 1994. Intracellular analysis of in vitro modified HIV Tat protein. J. Biol. Chem. 269:8366-8375.
32. Kundu, M., M. Guermah, R. G. Roeder, S. Amini, and K. Khalili. 1997. Interaction between cell cycle regulator E2F-1 and NF-κB mediates repression of HIV-1 gene transcription. J. Biol. Chem. 272:29468-29474.
33. Kunsch, C., S. M. Ruben, and C. A. Rosen. 1992. Selection of optimal κB/Rel DNA-binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Mol. Cell. Biol. 12:4412-4421.
34. LaMarco, K., C. C. Thompson, B. P. Byers, E. M. Walton, and S. L. McKnight. 1991. Identification of Ets- and Notch-related subunits in GA binding protein. Science 253:789-792.
35. Leiden, J. M., C.-Y. Wang, B. Petryniak, D. M. Markovitz, G. J. Nabel, and C. B. Thompson. 1992. A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells. J. Virol. 66:5890-5897.
36. Leonard, J., C. Parrott, A. J. Buckler White, W. Turner, E. K. Ross, M. A. Martin, and A. B. Rabson. 1989. The NF-kappa B binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity. J. Virol. 63:4919-4924.
37. Markovitz, D. M., M. J. Smith, J. Hilfinger, M. C. Hannibal, B. Petryniak, and G. J. Nabel. 1992. Activation of the human immunodeficiency virus type 2 enhancer is dependent on purine box and κB regulatory elements. J. Virol. 66:5479-5484.
38. Maury, W. 1998. Regulation of equine infectious anemia virus expression. J. Biomed. Sci. 5:11-23.
39. Montano, M. A., C. P. Nixon, and M. Essex. 1998. Dysregulation through the NF-κB enhancer and TATA box of the human immunodeficiency virus type 1 subtype E promoter. J. Virol. 72:8446-8452.
40. Montano, M. A., V. A. Novitskv, J. T. Blackard, N. L. Cho, D. A. Katzenstein, and M. Essex. 1997. Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypes. J. Virol. 71:8657-8665.
41. Myers, G., B. Korber, B. H. Hahn, K.-T. Jeang, J. H. Mellors, F. E. McCutchan, L. E. Henderson, and G. N. Pavlakis. 1995. Human retroviruses and AIDS. A compilation and analysis of nucleic acid and amino acid sequences. Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, N. Mex.
42. Nabel, G., and D. J. Baltimore. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T-cells. Nature 326:711-713.
43. Pope, M., S. S. Frankel, J. R. Mascola, A. Trkola, F. Isdell, D. L. Birx, D. S. Burke, D. D. Ho, and J. P. Moore. 1997. Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism. J. Virol. 71:8001-8007.
44. Rosmarin, A. G., D. G. Caprio, D. G. Kirsch, H. Handa, and C. P. Simkevich. 1995. GABP and PU.1 compete for binding, yet cooperate to increase CD 18 (beta 2 leukocyte integrin) transcription. J. Biol. Chem. 270:23627-23633.
45. Ross, E. K., A. J. Buckler White, A. B. Rabson, G. Englund, and M. A. Martin. 1991. Contribution of NF-kappa B and SpI binding motifs to the replicative capacity of human immunodeficiency virus type 1: distinct patterns of viral growth are determined by T-cell types. J. Virol. 65:4350-4358.
46. Savoysky, E., T. Mizuno, Y. Sowa, H. Watanabe, J. Sawada, H. Nomura, Y. Ohsugi, H. Handa, and T. Sakai. 1994. The retinoblastoma binding factor 1 (RBF-1) site in RB gene promoter binds preferentially E4TF1, a member of the Ets transcription factors family. Oncogene 9:1839-1846.
47. Schmid, R. M., S. Liptay, J. C. Betts, and G. J. Nabel. 1994. Structural and functional analysis of NF-κB. Determinants of DNA binding specificity and protein interaction. J. Biol. Chem. 269:32162-32167.
48. Schmid, R. M., N. D. Perkins, C. S. Duckett, P. C. Andrews, and G. J. Nabel. 1991. Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65. Nature 352:733-736.
49. Seed, B., and J. Y. Sheen. 1988. A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene 67:271-277.
50. Seth, A., D. R. Hodge, D. M. Thompson, L. Robinson, A. Panayiotakis, D. K. Watson, and T. S. Papas. 1993. Ets family proteins activate transcription from HIV-1 long terminal repeat. AIDS Res. Hum. Retroviruses 9:1017-1023.
51. Shiio, Y., J. Sawada, H. Handa, T. Yamamoto, and J. Inoue. 1996. Activation of the retinoblastoma gene expression by Bcl-3: implication for muscle cell differentiation. Oncogene 12:1837-1845.
52. Siebenlist, U., G. Franzoso, and K. Brown. 1994. Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol. 10:405-455.
53. Sieweke, M. H., H. Tekotte, U. Jarosch, and T. Graf. 1998. Cooperative interaction of Ets-1 with USF-1 required for HIV-I enhancer activity in T cells. EMBO J. 17:1728-1739.
54. Soto-Ramirez, L. E., B. Renjifo, M. F. McLane, R. Marlink, C. O'Hara, R. Sutthent, C. Wasi, P. Vithayasai, V. Vithayasai, C. Apichartpiyakul, P. Auewarakul, Pena Cruz V, D. S. Chui, R. Osathanondh, K. Mayer, T. H. Lee, and M. Essex. 1996. HIV-1 Langerhans cell tropism associated with heterosexual transmission of HIV. Science 271:1291-1293.
55. Sowa, Y., Y. Shiio, T. Fujita, T. Matsumoto, Y. Okuyama, D. Kato, J. Inoue, J. Sawada, M. Goto, H. Watanabe, H. Handa, and T. Sakai. 1997. Retinoblastoma binding factor 1 site in the core promoter region of the human RB gene is activated by hGABP/E4TF1. Cancer Res. 57:3145-3148.
56. Thanos, D., and T. Maniatis. 1995. NF-KB: a lesson in family values. Cell 80:529-532.
57. Tsichlis, P. N., and P. A. Lazo. 1991. Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses, p. 95-171. In H. J. Kung and P. K. Vogt (ed.), Retroviral insertion and oncogene activation. Springer-Verlag, Berlin, Germany.
58. Verhoef, K., M. Koper, and B. Berkhout. 1997. Determination of the minimal amount of Tat activity required for human immunodeficiency virus type 1 replication. Virology 237:228-236.
59. Watanabe, H., T. Imai, P. A. Sharp, and H. Handa. 1988. Identification of two transcription factors that bind to specific elements in the promoter of the adenovirus early-region 4. Mol. Cell. Biol. 8:1290-1300.
60. Wei, P., M. E. Garber, S.-M. Fang, W. H. Fisher, and K. A. Jones. 1998. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92:451-462.
61. Westendorp, M. O., V. A. Shatrov, K. Schulze-Osthoff, R. Frank, M. Kraft, M. Los, P. H. Krammer, W. Droge, and V. Lehmann. 1995. HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state. EMBO J. 14:546-554.