-
1
-
-
0030860068
-
Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors
-
Addison, C. L., M. Hitt, D. Kunsken, and F. L. Graham. 1997. Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors. J. Gen. Virol. 78:1653-1661.
-
(1997)
J. Gen. Virol.
, vol.78
, pp. 1653-1661
-
-
Addison, C.L.1
Hitt, M.2
Kunsken, D.3
Graham, F.L.4
-
2
-
-
0031958593
-
Scaffold attachment region-mediated enhancement of retroviral vector expression in primary T cells
-
Agarwal, M., T. W. Austin, F. Morel, J. Chen, E. Bohnlein, and I. Plavec. 1998. Scaffold attachment region-mediated enhancement of retroviral vector expression in primary T cells. J. Virol. 72:3729-3728.
-
(1998)
J. Virol.
, vol.72
, pp. 3729-13728
-
-
Agarwal, M.1
Austin, T.W.2
Morel, F.3
Chen, J.4
Bohnlein, E.5
Plavec, I.6
-
3
-
-
0028863880
-
Characterization of an adenovirus gene transfer vector containing an E4 deletion
-
Armentano, D., C. C. Sookdeo, K. M. Hehir, R. J. Gregory, St, G. A. Prince, S. C. Wadsworth, and A. E. Smith. 1995. Characterization of an adenovirus gene transfer vector containing an E4 deletion. Hum. Gene Ther. 6:1343-1353.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1343-1353
-
-
Armentano, D.1
Sookdeo, C.C.2
Hehir, K.M.3
St. Gregory, R.J.4
Prince, G.A.5
Wadsworth, S.C.6
Smith, A.E.7
-
4
-
-
0028207982
-
Compartmentalization of cellular and viral DNAs in adenovirus type 5 infection as revealed by ultrastructural in situ hybridization
-
Besse, S., and F. Puvion-Dutilleul. 1994. Compartmentalization of cellular and viral DNAs in adenovirus type 5 infection as revealed by ultrastructural in situ hybridization. Chromosome Res. 2:123-135.
-
(1994)
Chromosome Res.
, vol.2
, pp. 123-135
-
-
Besse, S.1
Puvion-Dutilleul, F.2
-
5
-
-
0027260609
-
Packaging capacity and stability of human adenovirus type 5 vectors
-
Bett, A. J., L. Prevec, and F. L. Graham. 1993. Packaging capacity and stability of human adenovirus type 5 vectors. J. Virol. 67:5911-5921.
-
(1993)
J. Virol.
, vol.67
, pp. 5911-5921
-
-
Bett, A.J.1
Prevec, L.2
Graham, F.L.3
-
6
-
-
0028857655
-
The use of adenoviral vectors for gene therapy and gene transfer in vivo
-
Bramson, J. L., F. L. Graham, and J. Gauldie. 1995. The use of adenoviral vectors for gene therapy and gene transfer in vivo. Curr. Opin. Biotechnol. 6:590-595.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 590-595
-
-
Bramson, J.L.1
Graham, F.L.2
Gauldie, J.3
-
7
-
-
0031049699
-
Persistence in muscle of an adenoviral vector that lacks all viral genes
-
Chen, H. H., L. M. Mack, R. Kelly, M. Ontell, S. Kochanek, and P. R. Clemens. 1997. Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc. Natl. Acad. Sci. USA 94:1645-1650.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1645-1650
-
-
Chen, H.H.1
Mack, L.M.2
Kelly, R.3
Ontell, M.4
Kochanek, S.5
Clemens, P.R.6
-
8
-
-
0030426525
-
Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre
-
Chen, L., M. Anton, and F. L. Graham. 1996. Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre. Somat. Cell. Mol. Genet. 22:477-488.
-
(1996)
Somat. Cell. Mol. Genet.
, vol.22
, pp. 477-488
-
-
Chen, L.1
Anton, M.2
Graham, F.L.3
-
9
-
-
0029857641
-
In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes
-
Clemens, P. R., S. Kochanek, Y. Sunada, S. Chan, H. H. Chen, K. P. Campbell, and C. T. Caskey. 1996. In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes. Gene Ther. 3:965-972.
-
(1996)
Gene Ther.
, vol.3
, pp. 965-972
-
-
Clemens, P.R.1
Kochanek, S.2
Sunada, Y.3
Chan, S.4
Chen, H.H.5
Campbell, K.P.6
Caskey, C.T.7
-
10
-
-
0029934754
-
Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides
-
Cowdery, J. S., J. H. Chace, A. K. Yi, and A. M. Krieg. 1996. Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J. Immunol. 156:4570-4575.
-
(1996)
J. Immunol.
, vol.156
, pp. 4570-4575
-
-
Cowdery, J.S.1
Chace, J.H.2
Yi, A.K.3
Krieg, A.M.4
-
11
-
-
0028934815
-
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
-
Dai, Y., E. M. Schwarz, D. Gu, W. W. Zhang, N. Sarvetnick, and I. M. Verma. 1995. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc. Natl. Acad. Sci. USA 92:1401-1405.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1401-1405
-
-
Dai, Y.1
Schwarz, E.M.2
Gu, D.3
Zhang, W.W.4
Sarvetnick, N.5
Verma, I.M.6
-
12
-
-
0031964257
-
CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
-
Davis, H. L., R. Weeranta, T. J. Waldschmidt, L. Tygrett, J. Schorr, and A. M. Krieg. 1998. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J. Immunol. 160:870-876.
-
(1998)
J. Immunol.
, vol.160
, pp. 870-876
-
-
Davis, H.L.1
Weeranta, R.2
Waldschmidt, T.J.3
Tygrett, L.4
Schorr, J.5
Krieg, A.M.6
-
13
-
-
0030923808
-
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses
-
Dedieu, J. F., E. Vigne, C. Torrent, C. Jullien, I. Mahfouz, J. M. Caillaud, N. Aubailly, C. Orsini, J. M. Guillaume, P. Opolon, P. Delaere, M. Perricaudet, and P. Yeh. 1997. Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses. J. Virol. 71:4626-4637.
-
(1997)
J. Virol.
, vol.71
, pp. 4626-4637
-
-
Dedieu, J.F.1
Vigne, E.2
Torrent, C.3
Jullien, C.4
Mahfouz, I.5
Caillaud, J.M.6
Aubailly, N.7
Orsini, C.8
Guillaume, J.M.9
Opolon, P.10
Delaere, P.11
Perricaudet, M.12
Yeh, P.13
-
14
-
-
0028246338
-
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
-
Engelhardt, J. F., X. Ye, B. Doranz, and J. M. Wilson. 1994. Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc. Natl. Acad. Sci. USA 91:6196-6200.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6196-6200
-
-
Engelhardt, J.F.1
Ye, X.2
Doranz, B.3
Wilson, J.M.4
-
15
-
-
0029670374
-
Lack of persistence of El-recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs
-
Fang, B., H. Wang, G. Gordon, D. A. Bellinger, M. S. Read, K. M. Brinkhous, S. L. Woo, and R. C. Eisensmith. 1996. Lack of persistence of El-recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs. Gene Ther. 3:217-222.
-
(1996)
Gene Ther.
, vol.3
, pp. 217-222
-
-
Fang, B.1
Wang, H.2
Gordon, G.3
Bellinger, D.A.4
Read, M.S.5
Brinkhous, K.M.6
Woo, S.L.7
Eisensmith, R.C.8
-
16
-
-
0029966514
-
Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis
-
Fisher, K. J., H. Choi, J. Burda, S. J. Chen, and J. M. Wilson. 1996. Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis. Virology 217:11-22.
-
(1996)
Virology
, vol.217
, pp. 11-22
-
-
Fisher, K.J.1
Choi, H.2
Burda, J.3
Chen, S.J.4
Wilson, J.M.5
-
17
-
-
0029959867
-
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
-
Gao, G. P., Y. Yang, and J. M. Wilson. 1996. Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J. Virol. 70:8934-8943.
-
(1996)
J. Virol.
, vol.70
, pp. 8934-8943
-
-
Gao, G.P.1
Yang, Y.2
Wilson, J.M.3
-
18
-
-
0028964343
-
Embryonic activation of the myoD gene is regulated by a highly conserved distal control element
-
Goldhamer, D. J., B. P. Brunk, A. Faerman, A. King, M. Shani, and C. P. Emerson, Jr. 1995. Embryonic activation of the myoD gene is regulated by a highly conserved distal control element. Development 121:637-649.
-
(1995)
Development
, vol.121
, pp. 637-649
-
-
Goldhamer, D.J.1
Brunk, B.P.2
Faerman, A.3
King, A.4
Shani, M.5
Emerson C.P., Jr.6
-
19
-
-
0026593562
-
Regulatory elements that control the lineage-specific expression of myoD
-
Goldhamer, D. J., A. Faerman, M. Shani, and C. P. Emerson, Jr. 1992. Regulatory elements that control the lineage-specific expression of myoD. Science 256:538-542.
-
(1992)
Science
, vol.256
, pp. 538-542
-
-
Goldhamer, D.J.1
Faerman, A.2
Shani, M.3
Emerson C.P., Jr.4
-
20
-
-
0029091783
-
Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: A preclinical toxicology study
-
Goldman, M. J., L. A. Litzky, J. F. Engelhardt, and J. M. Wilson. 1995. Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study. Hum. Gene Ther. 6:839-851.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 839-851
-
-
Goldman, M.J.1
Litzky, L.A.2
Engelhardt, J.F.3
Wilson, J.M.4
-
21
-
-
0029664338
-
Elimination of both E1 and E2 from adenovirus vectors further improves prospects for in vivo human gene therapy
-
Gorziglia, M. I., M. J. Kadan, S. Yei, J. Lim, G. M. Lee, R. Luthra, and B. C. Trapnell. 1996. Elimination of both E1 and E2 from adenovirus vectors further improves prospects for in vivo human gene therapy. J. Virol. 70: 4173-4178.
-
(1996)
J. Virol.
, vol.70
, pp. 4173-4178
-
-
Gorziglia, M.I.1
Kadan, M.J.2
Yei, S.3
Lim, J.4
Lee, G.M.5
Luthra, R.6
Trapnell, B.C.7
-
22
-
-
0021731779
-
Covalently closed circles of human adenovirus DNA are infectious
-
Graham, F. L. 1984. Covalently closed circles of human adenovirus DNA are infectious. EMBO J. 3:2917-2922.
-
(1984)
EMBO J.
, vol.3
, pp. 2917-2922
-
-
Graham, F.L.1
-
23
-
-
0017710978
-
Characteristic of a human cell line transformed by DNA from human adenovirus type 5
-
Graham, F. L., J. Smiley, W. C. Russell, and R. Nairn. 1977. Characteristic of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:59-74.
-
(1977)
J. Gen. Virol.
, vol.36
, pp. 59-74
-
-
Graham, F.L.1
Smiley, J.2
Russell, W.C.3
Nairn, R.4
-
24
-
-
0033577852
-
Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte
-
Guidotti, L. G., P. Borrow, A. Brown, H. McClary, R. Koch, and F. V. Chisari. 1999. Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte. J. Exp. Med. 189:1555-1564.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1555-1564
-
-
Guidotti, L.G.1
Borrow, P.2
Brown, A.3
McClary, H.4
Koch, R.5
Chisari, F.V.6
-
25
-
-
0033617583
-
Viral clearance without destruction of infected cells during acute HBV infection
-
Guidotti, L. G., R. Rochford, J. Chung, M. Shapiro, R. Purcell, and F. V. Chisari. 1999. Viral clearance without destruction of infected cells during acute HBV infection. Science 284:825-829.
-
(1999)
Science
, vol.284
, pp. 825-829
-
-
Guidotti, L.G.1
Rochford, R.2
Chung, J.3
Shapiro, M.4
Purcell, R.5
Chisari, F.V.6
-
26
-
-
0029962474
-
In vivo expression of full-length human dystrophin from adenoviral vectors deleted of all viral genes
-
Haecker, S. E., H. H. Stedman, R. J. Bailee-Gordon, D. B. Smith, J. P. Greelish, M. A. Mitchell, A. Wells, H. L. Sweeney, and J. M. Wilson. 1996. In vivo expression of full-length human dystrophin from adenoviral vectors deleted of all viral genes. Hum. Gene Ther. 7:1907-1914.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1907-1914
-
-
Haecker, S.E.1
Stedman, H.H.2
Bailee-Gordon, R.J.3
Smith, D.B.4
Greelish, J.P.5
Mitchell, M.A.6
Wells, A.7
Sweeney, H.L.8
Wilson, J.M.9
-
27
-
-
0031055468
-
Construction of adenovirus vectors through Cre-lox recombination
-
Hardy, S., M. Kitamura, T. Harris-Stansil, Y. Dai, and M. L. Phipps. 1997. Construction of adenovirus vectors through Cre-lox recombination. J. Virol. 71:1842-1849.
-
(1997)
J. Virol.
, vol.71
, pp. 1842-1849
-
-
Hardy, S.1
Kitamura, M.2
Harris-Stansil, T.3
Dai, Y.4
Phipps, M.L.5
-
28
-
-
77957042700
-
Techniques for human adenovirus vector construction and characterization
-
Hitt, M., A. J. Bett, C. L. Addison, L. Prevec, and F. L. Graham. 1995. Techniques for human adenovirus vector construction and characterization. Methods Mol. Genet. 7:13-30.
-
(1995)
Methods Mol. Genet.
, vol.7
, pp. 13-30
-
-
Hitt, M.1
Bett, A.J.2
Addison, C.L.3
Prevec, L.4
Graham, F.L.5
-
29
-
-
0030623809
-
Human adenovirus vectors for gene transfer into mammalian cells
-
Hitt, M. M., C. L. Addison, and F. L. Graham. 1997. Human adenovirus vectors for gene transfer into mammalian cells. Adv. Pharmacol. 40:137-206.
-
(1997)
Adv. Pharmacol.
, vol.40
, pp. 137-206
-
-
Hitt, M.M.1
Addison, C.L.2
Graham, F.L.3
-
30
-
-
0029743163
-
Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung
-
Jooss, K., Y. Yang, and J. M. Wilson. 1996. Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung. Hum. Gene Ther. 7:1555-1566.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1555-1566
-
-
Jooss, K.1
Yang, Y.2
Wilson, J.M.3
-
31
-
-
0032530110
-
Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: Implications for gene therapy
-
Kafri. T., D. Morgan, T. Krahl, N. Sarvetnick, L. Sherman, and I. Verma. 1998. Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy. Proc. Natl. Acad. Sci. USA 95:11377-11382.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11377-11382
-
-
Kafri, T.1
Morgan, D.2
Krahl, T.3
Sarvetnick, N.4
Sherman, L.5
Verma, I.6
-
32
-
-
0029968305
-
Circumventing the immune response to adenovirus-mediated gene therapy
-
Kass-Eisler, A., L. Leinwand, J. Gall, B. Bloom, and E. Falck-Pedersen. 1996. Circumventing the immune response to adenovirus-mediated gene therapy. Gene Ther. 3:154-162.
-
(1996)
Gene Ther.
, vol.3
, pp. 154-162
-
-
Kass-Eisler, A.1
Leinwand, L.2
Gall, J.3
Bloom, B.4
Falck-Pedersen, E.5
-
33
-
-
0029943155
-
A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase
-
Kochanek, S., P. R. Clemens, K. Mitani, H. H. Chen, S. Chan, and C. T. Caskey. 1996. A new adenoviral vector: replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase. Proc. Natl. Acad. Sci. USA 93:5731-5736.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5731-5736
-
-
Kochanek, S.1
Clemens, P.R.2
Mitani, K.3
Chen, H.H.4
Chan, S.5
Caskey, C.T.6
-
34
-
-
0029875608
-
Use of transient CD4 lymphocyte depletion to prolong transgene expression of E1-deleted adenoviral vectors
-
Kolls, J. K., D. Lei, G. Odom, S. Nelson, W. R. Summer, M. A. Gerber, and J. E. Shellito. 1996. Use of transient CD4 lymphocyte depletion to prolong transgene expression of E1-deleted adenoviral vectors. Hum. Gene Ther. 7:489-497.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 489-497
-
-
Kolls, J.K.1
Lei, D.2
Odom, G.3
Nelson, S.4
Summer, W.R.5
Gerber, M.A.6
Shellito, J.E.7
-
35
-
-
0032514616
-
Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs
-
Krieg, A. M., T. Wu, R. Weeratna, S. M. Efler, L. Love-Homan, L. Yang, A. K. Yi, D. Short, and H. L. Davis. 1998. Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs. Proc. Natl. Acad. Sci. USA 95:12531-12636.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12531-12636
-
-
Krieg, A.M.1
Wu, T.2
Weeratna, R.3
Efler, S.M.4
Love-Homan, L.5
Yang, L.6
Yi, A.K.7
Short, D.8
Davis, H.L.9
-
36
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg, A. M., A. K. Yi, S. Matson, T. J. Waldschmidt, G. A. Bishop, R. Teasdale, G. A, Koretzky, and D. M. Klinman. 1995. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374:546-549.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
37
-
-
0030016358
-
Encapsidated adenovirus minichromosomes allow delivery and expression of a 14 kb dystrophin cDNA to muscle cells
-
Kumar-Singh, R., and J. S. Chamberlain. 1996. Encapsidated adenovirus minichromosomes allow delivery and expression of a 14 kb dystrophin cDNA to muscle cells. Hum. Mol. Genet. 5:913-921.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 913-921
-
-
Kumar-Singh, R.1
Chamberlain, J.S.2
-
38
-
-
0030943732
-
Macrophage depletion increases the safety, efficacy and persistence of adenovirus-mediated gene transfer in vivo
-
Kuzmin, A. I., M. J. Finegold, and R. C. Eisensmith. 1997. Macrophage depletion increases the safety, efficacy and persistence of adenovirus-mediated gene transfer in vivo. Gene Ther. 4:309-316.
-
(1997)
Gene Ther.
, vol.4
, pp. 309-316
-
-
Kuzmin, A.I.1
Finegold, M.J.2
Eisensmith, R.C.3
-
39
-
-
0029861452
-
Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo
-
Lieber, A, C. Y. He, I. Kiroillova, and M. A. Kay. 1996. Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo. J. Virol. 70:8944-8960.
-
(1996)
J. Virol.
, vol.70
, pp. 8944-8960
-
-
Lieber, A.1
He, C.Y.2
Kiroillova, I.3
Kay, M.A.4
-
40
-
-
0029741231
-
Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice
-
Lochmuller, H., B. J. Petrof, G. Pari, N. Larochelle, V. Dodelet, Q. Wang, C. Allen, S. Prescott, B. Massie, J. Nalbantoglu, and G. Karpati. 1996. Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice. Gene Ther. 3:706-716.
-
(1996)
Gene Ther.
, vol.3
, pp. 706-716
-
-
Lochmuller, H.1
Petrof, B.J.2
Pari, G.3
Larochelle, N.4
Dodelet, V.5
Wang, Q.6
Allen, C.7
Prescott, S.8
Massie, B.9
Nalbantoglu, J.10
Karpati, G.11
-
41
-
-
0031888263
-
In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted
-
Lusky, M., M. Christ, K. Rittner, A. Dieterle, D. Dreyer, B. Mourot, H. Schultz, F. Stoeckel, A. Pavirani, and M. Mehtali. 1998. In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted. J. Virol. 72:2022-2032.
-
(1998)
J. Virol.
, vol.72
, pp. 2022-2032
-
-
Lusky, M.1
Christ, M.2
Rittner, K.3
Dieterle, A.4
Dreyer, D.5
Mourot, B.6
Schultz, H.7
Stoeckel, F.8
Pavirani, A.9
Mehtali, M.10
-
42
-
-
0030999469
-
Adenovirus-mediated gene transfer: Influence of transgene, mouse strain and type of immune response on persistence of transgene expression
-
Michou, A. I., L. Santoro, M. Christ, V. Julliard, A. Pavlrani, and M. Mehtali. 1997. Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression. Gene Ther. 4:473-482.
-
(1997)
Gene Ther.
, vol.4
, pp. 473-482
-
-
Michou, A.I.1
Santoro, L.2
Christ, M.3
Julliard, V.4
Pavlrani, A.5
Mehtali, M.6
-
43
-
-
0003785155
-
-
Cold Spring Harbor Laboratories, Cold Spring Harbor, N.Y.
-
Miller, J. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratories, Cold Spring Harbor, N.Y.
-
(1972)
Experiments in Molecular Genetics
-
-
Miller, J.1
-
44
-
-
0029054932
-
Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector
-
Mitani, K., F. L. Graham, C. T. Caskey, and S. Kochanek. 1995. Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector. Proc. Natl. Acad, Sci. USA 92:3854-3858.
-
(1995)
Proc. Natl. Acad, Sci. USA
, vol.92
, pp. 3854-3858
-
-
Mitani, K.1
Graham, F.L.2
Caskey, C.T.3
Kochanek, S.4
-
45
-
-
0030824640
-
Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: Comparison of E2a wild type and E2a deleted vectors
-
Morral, N., W. O'Neal, H. Zhou, C. Langston, and A. Beaudet. 1997. Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors. Hum. Gene Ther. 8:1275-1286.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1275-1286
-
-
Morral, N.1
O'Neal, W.2
Zhou, H.3
Langston, C.4
Beaudet, A.5
-
46
-
-
0032506791
-
High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha 1-antitrypsin with negligible toxicity
-
Morral, N., R. J. Parks, H. Zhou, C. Langston, G. Schiedner, J. Quinones, F. L. Graham, S. Kochanek, and A. L. Beaudet. 1998. High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha 1-antitrypsin with negligible toxicity. Hum. Gene Ther. 9:2709-2716.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2709-2716
-
-
Morral, N.1
Parks, R.J.2
Zhou, H.3
Langston, C.4
Schiedner, G.5
Quinones, J.6
Graham, F.L.7
Kochanek, S.8
Beaudet, A.L.9
-
47
-
-
13144283616
-
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene
-
Morsy, M. A., M. Gu, S. Motzel, J. Zhao, J. Lin, Q. Su, H. Allen, L. Franlin, R. J. Parks, F. L. Graham, S. Kochanek, A. J. Bett, and C. T. Caskey. 1998. An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc. Natl. Acad. Sci. USA 95:7866-7871.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7866-7871
-
-
Morsy, M.A.1
Gu, M.2
Motzel, S.3
Zhao, J.4
Lin, J.5
Su, Q.6
Allen, H.7
Franlin, L.8
Parks, R.J.9
Graham, F.L.10
Kochanek, S.11
Bett, A.J.12
Caskey, C.T.13
-
48
-
-
0030462599
-
A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
-
Parks, R. J., L. Chen, M. Anton, U. Sankar, M. A. Rudnicki, and F. L. Graham. 1996. A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc. Natl. Acad. Sci. USA 93:13565-13570.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13565-13570
-
-
Parks, R.J.1
Chen, L.2
Anton, M.3
Sankar, U.4
Rudnicki, M.A.5
Graham, F.L.6
-
49
-
-
0032827780
-
Use of helper-dependent adenoviral vectors of alternative serotype permits repeat vector administration
-
in press
-
Parks, R. J., C. M. Evelegh, and F. L. Graham. Use of helper-dependent adenoviral vectors of alternative serotype permits repeat vector administration. Gene Ther., in press.
-
Gene Ther.
-
-
Parks, R.J.1
Evelegh, C.M.2
Graham, F.L.3
-
50
-
-
0030900511
-
A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging
-
Parks, R. J., and F. L. Graham. 1997. A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging. J. Virol. 71:3293-3298.
-
(1997)
J. Virol.
, vol.71
, pp. 3293-3298
-
-
Parks, R.J.1
Graham, F.L.2
-
51
-
-
0029877620
-
Anti-T cell receptor monoclonal antibody prolongs transgene expression following adenovirus-mediated in vivo gene transfer to mouse synovium
-
Sawchuk, S. J., G. P. Boivin, L. E. Duwel, W. Ball, K. Bove, B. Trapnell, and R. Hirsch. 1996. Anti-T cell receptor monoclonal antibody prolongs transgene expression following adenovirus-mediated in vivo gene transfer to mouse synovium. Hum. Gene Ther. 7:499-506.
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 499-506
-
-
Sawchuk, S.J.1
Boivin, G.P.2
Duwel, L.E.3
Ball, W.4
Bove, K.5
Trapnell, B.6
Hirsch, R.7
-
52
-
-
0025314719
-
Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA
-
Schaack, J., W. Y. Ho, P. Freimuth, and T. Shenk. 1990. Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA. Genes Dev. 4:1197-1208.
-
(1990)
Genes Dev.
, vol.4
, pp. 1197-1208
-
-
Schaack, J.1
Ho, W.Y.2
Freimuth, P.3
Shenk, T.4
-
53
-
-
0031916435
-
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity
-
Schiedner, G., N. Morral, R. J. Parks, Y. Wu, S. C. Koopmans, C. Langston, F. L. Graham, A. L. Beaudet, and S. Kochanek. 1998. Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nat. Genet. 18:180-183.
-
(1998)
Nat. Genet.
, vol.18
, pp. 180-183
-
-
Schiedner, G.1
Morral, N.2
Parks, R.J.3
Wu, Y.4
Koopmans, S.C.5
Langston, C.6
Graham, F.L.7
Beaudet, A.L.8
Kochanek, S.9
-
54
-
-
0030240062
-
Macrophages ingest and are activated by bacterial DNA
-
Stacey, K. J., M. J. Sweet, and D. A. Hume. 1996. Macrophages ingest and are activated by bacterial DNA. J. Immunol. 157:2116-2122.
-
(1996)
J. Immunol.
, vol.157
, pp. 2116-2122
-
-
Stacey, K.J.1
Sweet, M.J.2
Hume, D.A.3
-
55
-
-
0023918513
-
Yeast ARS function and nuclear matrix association coincide in a short sequence from the human HPRT locus
-
Sykes, R. C, D. Lin, S. J. Hwang, P. E. Framson, and A. C. Chinault. 1988. Yeast ARS function and nuclear matrix association coincide in a short sequence from the human HPRT locus. Mol. Gen. Genet. 212:301-309.
-
(1988)
Mol. Gen. Genet.
, vol.212
, pp. 301-309
-
-
Sykes, R.C.1
Lin, D.2
Hwang, S.J.3
Framson, P.E.4
Chinault, A.C.5
-
56
-
-
0029936764
-
Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
-
Tripathy, S. K., H. B. Black, E. Goldwasser, and J. M. Leiden. 1996. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat. Med. 2:545-550.
-
(1996)
Nat. Med.
, vol.2
, pp. 545-550
-
-
Tripathy, S.K.1
Black, H.B.2
Goldwasser, E.3
Leiden, J.M.4
-
57
-
-
0028807696
-
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer
-
Vilquin, J. T., B. Guerette, I. Kinoshita, B. Roy, M. Goulet, C. Gravel, R. Roy, and J. P. Tremblay. 1995. FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer. Hum. Gene Ther. 6:1391-1401.
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 1391-1401
-
-
Vilquin, J.T.1
Guerette, B.2
Kinoshita, I.3
Roy, B.4
Goulet, M.5
Gravel, C.6
Roy, R.7
Tremblay, J.P.8
-
58
-
-
0030910842
-
Adenovirus vector-infected cells can escape adenovirus antigen-specific cytotoxic T-lymphocyte killing in vivo
-
Wadsworth, S. C., H. Zhou, A. E. Smith, and J. M. Kaplan. 1997. Adenovirus vector-infected cells can escape adenovirus antigen-specific cytotoxic T-lymphocyte killing in vivo. J. Virol. 71:5189-5196.
-
(1997)
J. Virol.
, vol.71
, pp. 5189-5196
-
-
Wadsworth, S.C.1
Zhou, H.2
Smith, A.E.3
Kaplan, J.M.4
-
59
-
-
0030820002
-
Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination
-
Wan, Y., J. Bramson, R. Carter, F. Graham, and J. Gauldie. 1997. Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination. Hum. Gene Ther. 8:1355-1363.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1355-1363
-
-
Wan, Y.1
Bramson, J.2
Carter, R.3
Graham, F.4
Gauldie, J.5
-
60
-
-
0031060294
-
Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ
-
Wolff, G., S. Worgall, R. N. van, W. R. Song, B. G. Harvey, and R. G. Crystal. 1997. Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. J. Virol. 71:624-629.
-
(1997)
J. Virol.
, vol.71
, pp. 624-629
-
-
Wolff, G.1
Worgall, S.2
Van, R.N.3
Song, W.R.4
Harvey, B.G.5
Crystal, R.G.6
-
61
-
-
0031034030
-
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
-
Worgall, S., G. Wolff, E. Falck-Pedersen, and R. G. Crystal. 1997. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum. Gene Ther. 8:37-44.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 37-44
-
-
Worgall, S.1
Wolff, G.2
Falck-Pedersen, E.3
Crystal, R.G.4
-
62
-
-
0029944988
-
Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver
-
Yang, Y., K. Greenough, and J. M. Wilson. 1996. Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver. Gene Ther. 3:412-420.
-
(1996)
Gene Ther.
, vol.3
, pp. 412-420
-
-
Yang, Y.1
Greenough, K.2
Wilson, J.M.3
-
63
-
-
0028937785
-
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
-
Yang, Y., Q. Li, H. C. Ertl, and J. M. Wilson. 1995. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J. Virol. 69:2004-2015.
-
(1995)
J. Virol.
, vol.69
, pp. 2004-2015
-
-
Yang, Y.1
Li, Q.2
Ertl, H.C.3
Wilson, J.M.4
-
64
-
-
0028328261
-
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
-
Yang, Y., F. A. Nunes, K. Berencsi, E. E. Furth, E. Gonczol, and J. M. Wilson. 1994. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA 91:4407-4411.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
Furth, E.E.4
Gonczol, E.5
Wilson, J.M.6
-
65
-
-
0028229147
-
Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis
-
Yang, Y., F. A. Nunes, K. Berencsi, E. Gonczol, J. F. Engelhardt, and J. M. Wilson. 1994. Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis. Nat. Genet. 7:362-369.
-
(1994)
Nat. Genet.
, vol.7
, pp. 362-369
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
Gonczol, E.4
Engelhardt, J.F.5
Wilson, J.M.6
-
66
-
-
0029093070
-
Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo
-
Yang, Y., Z. Xiang, H. C. Ertl, and J. M. Wilson. 1995. Upregulation of class I major histocompatibility complex antigens by Interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. Proc. Natl. Acad. Sci. USA 92:7257-7261.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7257-7261
-
-
Yang, Y.1
Xiang, Z.2
Ertl, H.C.3
Wilson, J.M.4
-
67
-
-
0029955391
-
Neonatal cotton rats do not exhibit destructive immune responses to adenoviral vectors
-
Zepeda, M., and J. M. Wilson. 1996. Neonatal cotton rats do not exhibit destructive immune responses to adenoviral vectors. Gene Ther. 3:973-979.
-
(1996)
Gene Ther.
, vol.3
, pp. 973-979
-
-
Zepeda, M.1
Wilson, J.M.2
|