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Volumn 7, Issue 13, 1996, Pages 1555-1566

Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYCLOPHOSPHAMIDE; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; NEUTRALIZING ANTIBODY;

EID: 0029743163     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.13-1555     Document Type: Article
Times cited : (144)

References (27)
  • 1
    • 0028914687 scopus 로고
    • Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains
    • BARR, D., TUBB, J., FERGUSON, D., SCARIA, A., LIEBER, A., WILSON, C., PERKINS, J., and KAY, M. (1995). Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther. 2, 151-155.
    • (1995) Gene Ther. , vol.2 , pp. 151-155
    • Barr, D.1    Tubb, J.2    Ferguson, D.3    Scaria, A.4    Lieber, A.5    Wilson, C.6    Perkins, J.7    Kay, M.8
  • 2
    • 0028033866 scopus 로고
    • Immunosuppressive drugs in clinical medicine
    • BERGE, R.J. (1994). Immunosuppressive drugs in clinical medicine. Netherlands J. Med. 45, 329-338.
    • (1994) Netherlands J. Med. , vol.45 , pp. 329-338
    • Berge, R.J.1
  • 3
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and ifosphamide by cytochromes P450 2B and 3A in human liver microsomes
    • CHANG, T.K.H., WEBER, G.F., CRESPI, C.L., and WAXMAN, D.J. (1993). Differential activation of cyclophosphamide and ifosphamide by cytochromes P450 2B and 3A in human liver microsomes. Cancer Res. 53, 5629-5637.
    • (1993) Cancer Res. , vol.53 , pp. 5629-5637
    • Chang, T.K.H.1    Weber, G.F.2    Crespi, C.L.3    Waxman, D.J.4
  • 4
    • 0028936342 scopus 로고
    • Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: Development of a combined chemotherapy/cancer gene therapy strategy
    • CHEN, L., and WAXMAN, D. (1995). Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy. Cancer Res. 55, 581-589.
    • (1995) Cancer Res. , vol.55 , pp. 581-589
    • Chen, L.1    Waxman, D.2
  • 5
    • 0024533623 scopus 로고
    • Oxidative metabolism of cyclophosphamide: Identification of the hepatic monooxygenase catalysts of drug activation
    • CLARKE, L., and WAXMAN, D.J. (1989). Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation. Cancer Res. 49, 2344-2350.
    • (1989) Cancer Res. , vol.49 , pp. 2344-2350
    • Clarke, L.1    Waxman, D.J.2
  • 6
    • 0028875936 scopus 로고
    • Transfer of genes to humans: Early lessons and obstacles to success
    • CRYSTAL, R. (1995). Transfer of genes to humans: early lessons and obstacles to success. Science 270, 404-410.
    • (1995) Science , vol.270 , pp. 404-410
    • Crystal, R.1
  • 7
    • 0028934815 scopus 로고
    • Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
    • DAI, Y., SCHWARZ, E., GU, D., ZHANG, W., SARVETNICK, N., and VERMA, I. (1995). Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression. Proc. Natl. Acad. Sci. USA 92, 1401-1405.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1401-1405
    • Dai, Y.1    Schwarz, E.2    Gu, D.3    Zhang, W.4    Sarvetnick, N.5    Verma, I.6
  • 8
    • 0028246338 scopus 로고
    • Ablation of E2a in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
    • ENGELHARDT, J.F., YE, X., DORANZ, B., and WILSON, J.M. (1994). Ablation of E2a in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc. Natl. Acad. Sci. USA 91, 6196-6200.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6196-6200
    • Engelhardt, J.F.1    Ye, X.2    Doranz, B.3    Wilson, J.M.4
  • 10
    • 0029113869 scopus 로고
    • Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4-Ig administration
    • KAY, M., HOLTERMAN, A.-x., MEUSE, L., GOWN, A., OCHS, H., LINSLEY, P., and WILSON, C. (1995). Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4-Ig administration. Nature Genet. 11, 191-197.
    • (1995) Nature Genet. , vol.11 , pp. 191-197
    • Kay, M.1    Holterman, A.-X.2    Meuse, L.3    Gown, A.4    Ochs, H.5    Linsley, P.6    Wilson, C.7
  • 13
    • 0029003826 scopus 로고
    • Oral therapy for small cell lung cancer
    • POSTMUS, P.E., and SMIT, E.F. (1995). Oral therapy for small cell lung cancer. Lung Cancer 12, 63-70.
    • (1995) Lung Cancer , vol.12 , pp. 63-70
    • Postmus, P.E.1    Smit, E.F.2
  • 15
    • 0025487393 scopus 로고
    • Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector
    • STRATFORD-PERRICAUDET, L., LEVRERO, M., CHASSE, J., PERRICAUDET, M., and BRIAND, P. (1990). Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector. Hum. Gene Ther. 1, 241-256.
    • (1990) Hum. Gene Ther. , vol.1 , pp. 241-256
    • Stratford-Perricaudet, L.1    Levrero, M.2    Chasse, J.3    Perricaudet, M.4    Briand, P.5
  • 16
    • 0029002881 scopus 로고
    • Immunosuppressive treatment of the pulmonary manifestations of progressive systemic sclerosis
    • VALLANCE, D.K., LYNCH, J.P., and McCUNE, W.J. (1995). Immunosuppressive treatment of the pulmonary manifestations of progressive systemic sclerosis. Curr. Opin. Rheumatol. 7, 174-182.
    • (1995) Curr. Opin. Rheumatol. , vol.7 , pp. 174-182
    • Vallance, D.K.1    Lynch, J.P.2    McCune, W.J.3
  • 17
    • 0027174822 scopus 로고
    • Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes
    • WEBER, G.F., and WAXMAN, D.J. (1993). Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes. Biochem. Pharmacol. 45, 1685-1694.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 1685-1694
    • Weber, G.F.1    Waxman, D.J.2
  • 18
    • 0028825747 scopus 로고
    • Gene therapy for cystic fibrosis: Challenges and future directions
    • WILSON, J.M. (1995). Gene therapy for cystic fibrosis: Challenges and future directions. J. Clin. Invest. 96, 2547-2554.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2547-2554
    • Wilson, J.M.1
  • 19
    • 0028484704 scopus 로고
    • MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
    • YANG, Y., ERTL, H.C.J., and WILSON, J.M. (1994c). MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1, 433-442.
    • (1994) Immunity , vol.1 , pp. 433-442
    • Yang, Y.1    Ertl, H.C.J.2    Wilson, J.M.3
  • 20
    • 0029944988 scopus 로고    scopus 로고
    • Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated transfer to mouse liver
    • YANG, Y., GREENOUGH, K., and WILSON, J.M. (1996). Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated transfer to mouse liver. Gene Ther. 3, 412-420.
    • (1996) Gene Ther. , vol.3 , pp. 412-420
    • Yang, Y.1    Greenough, K.2    Wilson, J.M.3
  • 21
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenovirus
    • YANG, Y., LI, Q., ERTL, H.C., and WILSON, J. (1995a). Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenovirus. J. Virol. 69, 2004-2015.
    • (1995) J. Virol. , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.4
  • 22
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
    • YANG, Y., NUNES, F., BERENCSI, K., FURTH, E., GONCZOL, E., and WILSON, J. (1994b). Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA 91, 4407-4411.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4407-4411
    • Yang, Y.1    Nunes, F.2    Berencsi, K.3    Furth, E.4    Gonczol, E.5    Wilson, J.6
  • 23
    • 0028229147 scopus 로고
    • Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy for cystic fibrosis
    • YANG, Y., NUNES, F.A., BERENCSI, K., GONCZOL, E., ENGELHARDT, J.E., and WILSON, J.M. (1994a). Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy for cystic fibrosis. Nature Genet. 7, 362-369.
    • (1994) Nature Genet. , vol.7 , pp. 362-369
    • Yang, Y.1    Nunes, F.A.2    Berencsi, K.3    Gonczol, E.4    Engelhardt, J.E.5    Wilson, J.M.6
  • 24
    • 0028978493 scopus 로고
    • Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung
    • YANG, Y., TRINCHIERI, G., and WILSON, J.M. (1995c). Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung. Nature Med. 1, 890-893.
    • (1995) Nature Med. , vol.1 , pp. 890-893
    • Yang, Y.1    Trinchieri, G.2    Wilson, J.M.3
  • 25
    • 0029093070 scopus 로고
    • Upregulation of class I MHC antigens by interferon-γ is necessary for the T cell-mediated elimination of recombinant adenovirus infected hepatocytes in vivo
    • YANG, Y., XIANG, Z., ERTL, H.C.J., and WILSON, J.M. (1995b). Upregulation of class I MHC antigens by interferon-γ is necessary for the T cell-mediated elimination of recombinant adenovirus infected hepatocytes in vivo. Proc. Natl. Acad. Sci. USA 92, 7257-7261.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7257-7261
    • Yang, Y.1    Xiang, Z.2    Ertl, H.C.J.3    Wilson, J.M.4
  • 26
    • 0028429545 scopus 로고
    • Adenovirus-mediated gene transfer for cystic fibrosis: Quantitative evaluation of repeated in vivo vector administration to the lung
    • YEI, S., MITTEREDER, N., TANG, K., O'SULLIVAN, C., and TRAPNELL, B.C. (1994). Adenovirus-mediated gene transfer for cystic fibrosis: quantitative evaluation of repeated in vivo vector administration to the lung. Gene Ther. 1, 192-200.
    • (1994) Gene Ther. , vol.1 , pp. 192-200
    • Yei, S.1    Mittereder, N.2    Tang, K.3    O'Sullivan, C.4    Trapnell, B.C.5
  • 27
    • 0028991829 scopus 로고
    • Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice
    • ZSENGELLER, Z., WERT, S., HULL, W., HU, X., YEI, S., TRAPNELL, B., and WHITSETT, J. (1995). Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice. Hum. Gene Ther. 6, 457-467.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 457-467
    • Zsengeller, Z.1    Wert, S.2    Hull, W.3    Hu, X.4    Yei, S.5    Trapnell, B.6    Whitsett, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.