메뉴 건너뛰기




Volumn 38, Issue 10, 1999, Pages 1621-1630

Selective activation of group II mGluRs with LY354740 does not prevent neuronal excitotoxicity

Author keywords

Excitotoxicity; Glutamate receptors; Neuronal death

Indexed keywords

EGLUMETAD; GLUTAMATE RECEPTOR AGONIST;

EID: 0032834689     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00098-2     Document Type: Article
Times cited : (27)

References (67)
  • 1
    • 0031739040 scopus 로고    scopus 로고
    • Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury
    • Agrawal S.K., Theriault E., Fehlings M.G. Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury. J. Neurotrauma. 15:1998;929-941.
    • (1998) J. Neurotrauma , vol.15 , pp. 929-941
    • Agrawal, S.K.1    Theriault, E.2    Fehlings, M.G.3
  • 2
    • 0029031548 scopus 로고
    • Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro
    • Ambrosini A., Bresciani L., Fracchia S., Brunello N., Racagni G. Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro. Mol. Pharmacol. 47:1995;1057-1064.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 1057-1064
    • Ambrosini, A.1    Bresciani, L.2    Fracchia, S.3    Brunello, N.4    Racagni, G.5
  • 3
    • 0025748026 scopus 로고
    • Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses
    • Aniksztejn L., Bregestovski P., Ben-Ari Y. Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses. Eur. J. Pharmacol. 3:1991;327-328.
    • (1991) Eur. J. Pharmacol. , vol.3 , pp. 327-328
    • Aniksztejn, L.1    Bregestovski, P.2    Ben-Ari, Y.3
  • 4
    • 0032907608 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Electrophysiological properties and role in plasticity
    • Anwyl R. Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res. Rev. 29:1999;83-120.
    • (1999) Brain Res. Rev. , vol.29 , pp. 83-120
    • Anwyl, R.1
  • 5
    • 0030904243 scopus 로고    scopus 로고
    • A novel orally active group 2 metabotropic glutamate receptor agonist: LY354740
    • Bond A., Monn J.A., Lodge D. A novel orally active group 2 metabotropic glutamate receptor agonist: LY354740. NeuroReport. 8:1997;1463-1466.
    • (1997) NeuroReport , vol.8 , pp. 1463-1466
    • Bond, A.1    Monn, J.A.2    Lodge, D.3
  • 6
    • 0032550103 scopus 로고    scopus 로고
    • Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia
    • Bond A., O'Neill M.J., Hicks C.A., Monn J.A., Lodge D. Neuroprotective effects of a systemically active group II metabotropic glutamate receptor agonist LY354740 in a gerbil model of global ischaemia. Neuroreport. 20:1998;1191-1193.
    • (1998) Neuroreport , vol.20 , pp. 1191-1193
    • Bond, A.1    O'Neill, M.J.2    Hicks, C.A.3    Monn, J.A.4    Lodge, D.5
  • 7
    • 0028351384 scopus 로고
    • Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death
    • Bruno V., Copani A., Battaglia G., Raffaele R., Shinozaki H., Nicoletti F. Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death. Eur. J. Pharmacol. 256:1994;109-112.
    • (1994) Eur. J. Pharmacol. , vol.256 , pp. 109-112
    • Bruno, V.1    Copani, A.2    Battaglia, G.3    Raffaele, R.4    Shinozaki, H.5    Nicoletti, F.6
  • 8
    • 0029131714 scopus 로고
    • Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells
    • Bruno V., Copani A., Knöpfel T., Kuhn R., Casabona G., Dell' Albani P., Condorelli D.F., Nicoletti F. Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. Neuropharmacology. 34:1995;1089-1098.
    • (1995) Neuropharmacology , vol.34 , pp. 1089-1098
    • Bruno, V.1    Copani, A.2    Knöpfel, T.3    Kuhn, R.4    Casabona, G.5    Dell' Albani, P.6    Condorelli, D.F.7    Nicoletti, F.8
  • 9
    • 0031032470 scopus 로고    scopus 로고
    • The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling
    • Bruno V., Sureda F.X., Storto M., Casabona G., Caruso A., Knopfel T., Kuhn R., Nicoletti F. The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling. J. Neurosci. 17:1997;1891-1897.
    • (1997) J. Neurosci. , vol.17 , pp. 1891-1897
    • Bruno, V.1    Sureda, F.X.2    Storto, M.3    Casabona, G.4    Caruso, A.5    Knopfel, T.6    Kuhn, R.7    Nicoletti, F.8
  • 11
    • 0032403407 scopus 로고    scopus 로고
    • Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β
    • Bruno V., Battaglia G., Casabona G., Copani A., Caciagli F., Nicoletti F. Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β J. Neurosci. 18:1998;9594-9600.
    • (1998) J. Neurosci. , vol.18 , pp. 9594-9600
    • Bruno, V.1    Battaglia, G.2    Casabona, G.3    Copani, A.4    Caciagli, F.5    Nicoletti, F.6
  • 12
    • 0033046392 scopus 로고    scopus 로고
    • Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): Comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors
    • Bruno V., Battaglia G., Kingston A., O'Neill M.J., Catania M.V., Di Grezia R., Nicoletti F. Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. Neuropharmacology. 38:1999;199-207.
    • (1999) Neuropharmacology , vol.38 , pp. 199-207
    • Bruno, V.1    Battaglia, G.2    Kingston, A.3    O'Neill, M.J.4    Catania, M.V.5    Di Grezia, R.6    Nicoletti, F.7
  • 13
    • 0345200964 scopus 로고
    • Metabotropic glutamate receptor activation attenuates NMDA-induced injury in cortical cell culture
    • J. Krieglstein, & H. Oberpichler-Schwenk. Stuttgart: Wissenshaftliche Verlagsgesellschaft mbH
    • Buisson A., Choi D.W. Metabotropic glutamate receptor activation attenuates NMDA-induced injury in cortical cell culture. Krieglstein J., Oberpichler-Schwenk H. Pharmacology of Cerebral Ischemia. 1994;109-114 Wissenshaftliche Verlagsgesellschaft mbH, Stuttgart.
    • (1994) Pharmacology of Cerebral Ischemia , pp. 109-114
    • Buisson, A.1    Choi, D.W.2
  • 14
    • 0029156276 scopus 로고
    • The inhibitory mGluR agonist, s-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death
    • Buisson A., Choi D.W. The inhibitory mGluR agonist, s-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death. Neuropharmacology. 34:1995;1081-1087.
    • (1995) Neuropharmacology , vol.34 , pp. 1081-1087
    • Buisson, A.1    Choi, D.W.2
  • 15
    • 0030031001 scopus 로고    scopus 로고
    • DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons
    • Buisson A., Yu S.P., Choi D.W. DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons. Eur. J. Neurosci. 8:1996;138-143.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 138-143
    • Buisson, A.1    Yu, S.P.2    Choi, D.W.3
  • 17
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1:1988;623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 18
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D.W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 19
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • Conn P.J., Pin J.P. Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37:1997;205-237.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 205-237
    • Conn, P.J.1    Pin, J.P.2
  • 20
    • 0032555221 scopus 로고    scopus 로고
    • Direct effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-D-aspartate receptors
    • Contractor A., Gereau R.W. IV, Green T., Heinemann S.F. Direct effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-D-aspartate receptors. Proc. Natl. Acad. Sci. USA. 95:1998;8969-8974.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8969-8974
    • Contractor, A.1    Gereau R.W. IV2    Green, T.3    Heinemann, S.F.4
  • 21
    • 0029934233 scopus 로고    scopus 로고
    • Additive neuroprotective effects of dextrorphan and cycloheximide in rats subjected to transient focal cerebral ischemia
    • Du C., Hu R., Csernansky C.A., Liu X.Z., Hsu C.Y., Choi D.W. Additive neuroprotective effects of dextrorphan and cycloheximide in rats subjected to transient focal cerebral ischemia. Brain Res. 718:1996;233-236.
    • (1996) Brain Res. , vol.718 , pp. 233-236
    • Du, C.1    Hu, R.2    Csernansky, C.A.3    Liu, X.Z.4    Hsu, C.Y.5    Choi, D.W.6
  • 22
    • 0028940419 scopus 로고
    • Metabotropic glutamate receptor agonists inhibit endogenous glutamate release from rat striatal synaptosomes
    • East S.J., Hill M.P., Brotchie J.M. Metabotropic glutamate receptor agonists inhibit endogenous glutamate release from rat striatal synaptosomes. Eur. J. Pharmacol. 277:1995;117-121.
    • (1995) Eur. J. Pharmacol. , vol.277 , pp. 117-121
    • East, S.J.1    Hill, M.P.2    Brotchie, J.M.3
  • 23
    • 0030976995 scopus 로고    scopus 로고
    • Evidence against a permissive role of the metabotropic glutamate receptor 1 in acute excitotoxicity
    • Ferraguti F., Pietra C., Valerio E., Corti C., Chiamulera C., Conquet F. Evidence against a permissive role of the metabotropic glutamate receptor 1 in acute excitotoxicity. Neuroscience. 79:1997;1-5.
    • (1997) Neuroscience , vol.79 , pp. 1-5
    • Ferraguti, F.1    Pietra, C.2    Valerio, E.3    Corti, C.4    Chiamulera, C.5    Conquet, F.6
  • 25
    • 0024805137 scopus 로고
    • Rodent models of cerebral ischemia
    • Ginsberg M.D., Busto R. Rodent models of cerebral ischemia. Stroke. 20:1989;1627-1642.
    • (1989) Stroke , vol.20 , pp. 1627-1642
    • Ginsberg, M.D.1    Busto, R.2
  • 26
    • 0027328680 scopus 로고
    • Combined oxygen and glucose deprivation in cortical cell culture: Calcium-dependent and calcium-independent mechanisms of neuronal injury
    • Goldberg M.P., Choi D.W. Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J. Neurosci. 13:1993;3510-3524.
    • (1993) J. Neurosci. , vol.13 , pp. 3510-3524
    • Goldberg, M.P.1    Choi, D.W.2
  • 27
    • 0026756866 scopus 로고
    • Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells
    • Hayashi Y., Tanabe Y., Aramori I., Masu M., Shimamoto K., Ohfune Y., Nakanishi S. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br. J. Pharmacol. 107:1992;539-543.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 539-543
    • Hayashi, Y.1    Tanabe, Y.2    Aramori, I.3    Masu, M.4    Shimamoto, K.5    Ohfune, Y.6    Nakanishi, S.7
  • 28
    • 0028350739 scopus 로고
    • Analysis of agonist and antagonist activities of phenylglycine derivates for different cloned metabotropic glutamate receptor subtypes
    • Hayashi Y., Sekiyama N., Nakanishi S., Jane D.E., Sunter D.C., Birse E.F., Udvarhelyi P.M., Watkins J.C. Analysis of agonist and antagonist activities of phenylglycine derivates for different cloned metabotropic glutamate receptor subtypes. J. Neurosci. 14:1994;3370-3377.
    • (1994) J. Neurosci. , vol.14 , pp. 3370-3377
    • Hayashi, Y.1    Sekiyama, N.2    Nakanishi, S.3    Jane, D.E.4    Sunter, D.C.5    Birse, E.F.6    Udvarhelyi, P.M.7    Watkins, J.C.8
  • 29
    • 0032550097 scopus 로고    scopus 로고
    • The mGlu receptor ligand (S)-4C3HPG protects neurons after global ischaemia in gerbils
    • Henrich-Noack P., Hatton C.D., Reymann K.G. The mGlu receptor ligand (S)-4C3HPG protects neurons after global ischaemia in gerbils. NeuroReport. 20:1998;985-988.
    • (1998) NeuroReport , vol.20 , pp. 985-988
    • Henrich-Noack, P.1    Hatton, C.D.2    Reymann, K.G.3
  • 30
    • 0033556391 scopus 로고    scopus 로고
    • (1S,3R)-ACPD, a metabotropic glutamate receptor agonist, enhances damage after global ischaemia
    • Henrich-Noack P., Reymann K.G. (1S,3R)-ACPD, a metabotropic glutamate receptor agonist, enhances damage after global ischaemia. Eur. J. Pharmacol. 365:1999;55-58.
    • (1999) Eur. J. Pharmacol. , vol.365 , pp. 55-58
    • Henrich-Noack, P.1    Reymann, K.G.2
  • 31
    • 0029131705 scopus 로고
    • New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord
    • Jane D.E., Pittaway K., Sunter D.C., Thomas N.K., Watkins J.C. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology. 34:1995;851-856.
    • (1995) Neuropharmacology , vol.34 , pp. 851-856
    • Jane, D.E.1    Pittaway, K.2    Sunter, D.C.3    Thomas, N.K.4    Watkins, J.C.5
  • 32
    • 0030472537 scopus 로고    scopus 로고
    • Potent antagonists at the L-AP4- And (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord
    • Jane D.E., Thomas N.K., Tse H.W., Watkins J.C. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord. Neuropharmacology. 35:1996;1029-1035.
    • (1996) Neuropharmacology , vol.35 , pp. 1029-1035
    • Jane, D.E.1    Thomas, N.K.2    Tse, H.W.3    Watkins, J.C.4
  • 33
    • 0029043591 scopus 로고
    • Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: Comparison with mGluR1
    • Joly C., Gomeza J., Brabet I., Curry K., Bockaert J., Pin J.P. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J. Neurosci. 15:1995;3970-3981.
    • (1995) J. Neurosci. , vol.15 , pp. 3970-3981
    • Joly, C.1    Gomeza, J.2    Brabet, I.3    Curry, K.4    Bockaert, J.5    Pin, J.P.6
  • 34
    • 0023221068 scopus 로고
    • Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
    • Koh J.Y., Choi D.W. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Methods. 20:1987;83-90.
    • (1987) J. Neurosci. Methods , vol.20 , pp. 83-90
    • Koh, J.Y.1    Choi, D.W.2
  • 35
    • 0026093753 scopus 로고
    • Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures
    • Koh J.Y., Palmer E., Cotman C.W. Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures. Proc. Natl. Acad. Sci. USA. 88:1991;9431-9435.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9431-9435
    • Koh, J.Y.1    Palmer, E.2    Cotman, C.W.3
  • 36
    • 0032566556 scopus 로고    scopus 로고
    • Effects of the metabotropic glutamate agonist LY354740 in a rat model of permanent ischaemia
    • Lam A.G.M., Soriano M.A., Monn J.A., Schoepp D.D., Lodge D., McCulloch J. Effects of the metabotropic glutamate agonist LY354740 in a rat model of permanent ischaemia. Neurosci. Lett. 254:1998;121-123.
    • (1998) Neurosci. Lett. , vol.254 , pp. 121-123
    • Lam, A.G.M.1    Soriano, M.A.2    Monn, J.A.3    Schoepp, D.D.4    Lodge, D.5    McCulloch, J.6
  • 37
    • 0027519254 scopus 로고
    • Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
    • Lin T.N., He Y.Y., Wu G., Khan M., Hsu C.Y. Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke. 24:1993;117-121.
    • (1993) Stroke , vol.24 , pp. 117-121
    • Lin, T.N.1    He, Y.Y.2    Wu, G.3    Khan, M.4    Hsu, C.Y.5
  • 39
    • 0028933282 scopus 로고
    • Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3
    • Lovinger D.M., McCool B.A. Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3. J. Neurophysiol. 73:1995;1076-1083.
    • (1995) J. Neurophysiol. , vol.73 , pp. 1076-1083
    • Lovinger, D.M.1    McCool, B.A.2
  • 40
    • 0024787764 scopus 로고
    • Quantitative assessment of neuroprotection against NMDA-induced brain injury
    • McDonald J.W., Roeser N.F., Silverstein F.S., Johnston M.V. Quantitative assessment of neuroprotection against NMDA-induced brain injury. Exp. Neurol. 106:1989;289-296.
    • (1989) Exp. Neurol. , vol.106 , pp. 289-296
    • McDonald, J.W.1    Roeser, N.F.2    Silverstein, F.S.3    Johnston, M.V.4
  • 41
    • 0027138725 scopus 로고
    • Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist
    • McDonald J.W., Fix A.S., Tizzano J.P., Schoepp D.D. Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist. J. Neurosci. 13:1993;4445-4455.
    • (1993) J. Neurosci. , vol.13 , pp. 4445-4455
    • McDonald, J.W.1    Fix, A.S.2    Tizzano, J.P.3    Schoepp, D.D.4
  • 42
    • 0025390880 scopus 로고
    • Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission
    • Meldrum B. Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission. Cerebrovasc. Brain Metab. Rev. 2:1990;27-57.
    • (1990) Cerebrovasc. Brain Metab. Rev. , vol.2 , pp. 27-57
    • Meldrum, B.1
  • 43
    • 15644369847 scopus 로고    scopus 로고
    • Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): A potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties
    • Monn J.A., Valli M.J., Massey S.M., Wright R.A., Salhoff C.R., Johnson B.G., Howe T., Alt C.A., Rhodes G.A., Robey R.L., Griffey K.R., Tizzano J.P., Kallman M.J., Helton D.R., Schoepp D.D. Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties. J. Med. Chem. 14:1997;528-537.
    • (1997) J. Med. Chem. , vol.14 , pp. 528-537
    • Monn, J.A.1    Valli, M.J.2    Massey, S.M.3    Wright, R.A.4    Salhoff, C.R.5    Johnson, B.G.6    Howe, T.7    Alt, C.A.8    Rhodes, G.A.9    Robey, R.L.10    Griffey, K.R.11    Tizzano, J.P.12    Kallman, M.J.13    Helton, D.R.14    Schoepp, D.D.15
  • 44
    • 0026763141 scopus 로고
    • Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin
    • Monyer H., Giffard R.G., Hartley D.M., Dugan L.L., Goldberg M.P., Choi D.W. Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin. Neuron. 8:1992;967-973.
    • (1992) Neuron , vol.8 , pp. 967-973
    • Monyer, H.1    Giffard, R.G.2    Hartley, D.M.3    Dugan, L.L.4    Goldberg, M.P.5    Choi, D.W.6
  • 45
    • 0030757919 scopus 로고    scopus 로고
    • MGluR modulation of post-traumatic neuronal death: Role of NMDA receptors
    • Mukhin A.G., Ivanova S.A., Faden A.I. mGluR modulation of post-traumatic neuronal death: role of NMDA receptors. Neuroreport. 8:1997;2561-2566.
    • (1997) Neuroreport , vol.8 , pp. 2561-2566
    • Mukhin, A.G.1    Ivanova, S.A.2    Faden, A.I.3
  • 46
    • 0028362472 scopus 로고
    • The metabotropic glutamate receptor antagonist (+)-α-methyl-4-carboxyphenylglycine protects hippocampal CA1 neurons of the rat from in vitro hypoxia/hypoglycemia
    • Opitz T., Richter P., Reymann K.G. The metabotropic glutamate receptor antagonist (+)-α-methyl-4-carboxyphenylglycine protects hippocampal CA1 neurons of the rat from in vitro hypoxia/hypoglycemia. Neuropharmacology. 33:1994;715-717.
    • (1994) Neuropharmacology , vol.33 , pp. 715-717
    • Opitz, T.1    Richter, P.2    Reymann, K.G.3
  • 47
    • 0029561263 scopus 로고
    • Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions
    • Orlando L.R., Standaert D.G., Penney J.B. Jr., Young A.B. Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neurosci. Lett. 202:1995;109-112.
    • (1995) Neurosci. Lett. , vol.202 , pp. 109-112
    • Orlando, L.R.1    Standaert, D.G.2    Penney J.B., Jr.3    Young, A.B.4
  • 48
    • 0028912822 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin J.P., Duvoisin R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology. 34:1995;1-26.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 50
    • 0027988094 scopus 로고
    • Activation of postsynaptic metabotropic glutamate receptors by trans-ACPD hyperpolarizes neurons of the basolateral amygdala
    • Rainnie D.G., Holmes K.H., Shinnick-Gallagher P. Activation of postsynaptic metabotropic glutamate receptors by trans-ACPD hyperpolarizes neurons of the basolateral amygdala. J. Neurosci. 14:1994;7208-7220.
    • (1994) J. Neurosci. , vol.14 , pp. 7208-7220
    • Rainnie, D.G.1    Holmes, K.H.2    Shinnick-Gallagher, P.3
  • 52
    • 0026513647 scopus 로고
    • Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage
    • Sacaan A.I., Schoepp D.D. Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage. Neurosci. Lett. 11:1992;77-82.
    • (1992) Neurosci. Lett. , vol.11 , pp. 77-82
    • Sacaan, A.I.1    Schoepp, D.D.2
  • 53
    • 0030745168 scopus 로고    scopus 로고
    • Pharmacological characterization of metabotropic glutamate receptors linked to the inhibition of adenylate cyclase activity in rat striatal slices
    • Schaffhauser H., Cartmell J., Jakob-Røtne R., Mutel V. Pharmacological characterization of metabotropic glutamate receptors linked to the inhibition of adenylate cyclase activity in rat striatal slices. Neuropharmacology. 36:1997;933-940.
    • (1997) Neuropharmacology , vol.36 , pp. 933-940
    • Schaffhauser, H.1    Cartmell, J.2    Jakob-Røtne, R.3    Mutel, V.4
  • 55
    • 0031683115 scopus 로고    scopus 로고
    • Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist
    • Schoepp D.D., Johnson B.G., Wright R.A., Salhoff C.R., Monn J.A. Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist. Naunym Schmieddeberg Arch. Pharmacol. 358:1998;175-180.
    • (1998) Naunym Schmieddeberg Arch. Pharmacol. , vol.358 , pp. 175-180
    • Schoepp, D.D.1    Johnson, B.G.2    Wright, R.A.3    Salhoff, C.R.4    Monn, J.A.5
  • 56
    • 0029871695 scopus 로고    scopus 로고
    • Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes
    • Sekiyama N., Hayashi Y., Nakanishi S., Jane D.E., Tse H.W., Birse E.F., Watkins J.C. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br. J. Pharmacol. 117:1996;1493-1503.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1493-1503
    • Sekiyama, N.1    Hayashi, Y.2    Nakanishi, S.3    Jane, D.E.4    Tse, H.W.5    Birse, E.F.6    Watkins, J.C.7
  • 57
    • 0026630435 scopus 로고
    • Metabotropic glutamate receptor agonists reduce epileptiform activity in the rat cortex
    • Sheardown M.J. Metabotropic glutamate receptor agonists reduce epileptiform activity in the rat cortex. Neuroreport. 3:1992;916-918.
    • (1992) Neuroreport , vol.3 , pp. 916-918
    • Sheardown, M.J.1
  • 58
    • 0026693076 scopus 로고
    • Activation of the glutamate metabotropic receptor protects retina against N-methyl-D-aspartate toxicity
    • Siliprandi R., Lipartiti M., Fadda E., Sautter J., Manev H. Activation of the glutamate metabotropic receptor protects retina against N-methyl-D-aspartate toxicity. Eur. J. Pharmacol. 14:1992;173-174.
    • (1992) Eur. J. Pharmacol. , vol.14 , pp. 173-174
    • Siliprandi, R.1    Lipartiti, M.2    Fadda, E.3    Sautter, J.4    Manev, H.5
  • 59
    • 0032465939 scopus 로고    scopus 로고
    • Antagonists for mGluR1 attenuate excitotoxic neuronal death in cortical cultures
    • Strasser U., Lobner D., Behrens M.M., Choi D.W. Antagonists for mGluR1 attenuate excitotoxic neuronal death in cortical cultures. Eur. J. Neurosci. 10:1998;2848-2855.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2848-2855
    • Strasser, U.1    Lobner, D.2    Behrens, M.M.3    Choi, D.W.4
  • 60
    • 0345632801 scopus 로고    scopus 로고
    • The mGluR1 antagonist PHCCC attenuates several forms of excitotoxic neuronal death
    • Strasser U., Behrens M.M., Choi D.W. The mGluR1 antagonist PHCCC attenuates several forms of excitotoxic neuronal death. Eur. J. Neurosci. (suppl.). 10:1998;204.
    • (1998) Eur. J. Neurosci. (Suppl.) , vol.10 , pp. 204
    • Strasser, U.1    Behrens, M.M.2    Choi, D.W.3
  • 62
    • 0030926112 scopus 로고    scopus 로고
    • Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats
    • Tang E., Yip P.K., Chapman A.G., Jane D.E., Meldrum B.S. Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats. Eur. J. Pharmacol. 327:1997;109-115.
    • (1997) Eur. J. Pharmacol. , vol.327 , pp. 109-115
    • Tang, E.1    Yip, P.K.2    Chapman, A.G.3    Jane, D.E.4    Meldrum, B.S.5
  • 63
    • 0028365897 scopus 로고
    • (S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice
    • Thomsen C., Klitgaard H., Sheardown M., Jackson H.C., Eskesen K., Jacobsen P., Treppendahl S., Suzdak P.D. (S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice. J. Neurochem. 62:1994;2492-2495.
    • (1994) J. Neurochem. , vol.62 , pp. 2492-2495
    • Thomsen, C.1    Klitgaard, H.2    Sheardown, M.3    Jackson, H.C.4    Eskesen, K.5    Jacobsen, P.6    Treppendahl, S.7    Suzdak, P.D.8
  • 64
    • 0028236468 scopus 로고
    • Actions of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) in retinal ON bipolar cells indicate that it is an agonist at L-AP4 receptors
    • Thoreson W.B., Miller R.F. Actions of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) in retinal ON bipolar cells indicate that it is an agonist at L-AP4 receptors. J. Gen. Physiol. 103:1994;1019-1034.
    • (1994) J. Gen. Physiol. , vol.103 , pp. 1019-1034
    • Thoreson, W.B.1    Miller, R.F.2
  • 65
    • 0029584760 scopus 로고
    • Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus
    • Ugolini A., Bordi F. Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus. Eur. J. Pharmacol. 294:1995;403-410.
    • (1995) Eur. J. Pharmacol. , vol.294 , pp. 403-410
    • Ugolini, A.1    Bordi, F.2
  • 66
    • 0029874770 scopus 로고    scopus 로고
    • A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus
    • Yoshino M., Sawada S., Yamamoto C., Kamiya H. A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus. Neurosci. Lett. 207:1996;70-72.
    • (1996) Neurosci. Lett. , vol.207 , pp. 70-72
    • Yoshino, M.1    Sawada, S.2    Yamamoto, C.3    Kamiya, H.4
  • 67
    • 0031950950 scopus 로고    scopus 로고
    • Group III human metabotropic glutamate receptors 4,7 and 8: Molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells
    • Wu S., Wright R.A., Rockey P.K., Burgett S.G., Arnold J.S., Rosteck P.R. Jr., Johnson B.G., Schoepp D.D., Belagaje R.M. Group III human metabotropic glutamate receptors 4,7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells. Mol. Brain Res. 53:1998;88-97.
    • (1998) Mol. Brain Res. , vol.53 , pp. 88-97
    • Wu, S.1    Wright, R.A.2    Rockey, P.K.3    Burgett, S.G.4    Arnold, J.S.5    Rosteck P.R., Jr.6    Johnson, B.G.7    Schoepp, D.D.8    Belagaje, R.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.