Metabotropic glutamate receptors and neurodegeneration

Progress in Brain Research

Volumn 116, Issue , 1998, Pages 209-221

  Bruno, V ^a   Battaglia, G ^a   Copani, A ^a   Casabona, G ^a   Storto, M ^a   Di Giorgi Gerevini, V ^a   Ngomba, R ^a   Nicoletti, F ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 3,5 DIHYDROXYPHENYLGLYCINE; 4 CARBOXY 3 HYDROXYPHENYLGLYCINE; 4 CARBOXYPHENYLGLYCINE; ALPHA METHYL 4 PHOSPHONOPHENYLGLYCINE; CYCLOPROPANECARBOXYLIC ACID DERIVATIVE; DIZOCILPINE; EGLUMETAD; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHOSERINE; QUISQUALIC ACID;

ASTROCYTE; BRAIN ISCHEMIA; CLINICAL TRIAL; HUMAN; INTRACEREBRAL DRUG ADMINISTRATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0031791012     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0079-6123(08)60439-2     Document Type: Review

References (73)

1. T. Abe R. Shigemoto S. Nakanishi Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal trans-duction J. Biol. Chem. 267 1992 13361 13367
2. A. Aiba C. Chen Herrup K. C. Rosenmund C.F. Stevens S. Tonegawa Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluRl mutant mice Cell 79 1994 365 375
3. A. Aiba M. Kano C. Chen M.E. Stanton G.D. Fox K. Herrup T.A. Zwingman S. Tonegawa Deficient cerebellar long-term depression and impaired motor learning in mGluRl mutant mice Cell 79 1994 377 388
4. A.L. Ambrosini S. Bresciani N. Fracchia N. Brunello G. Racagni Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro Mol. Pharmacol. 47 1995 1057 1064
5. H. Annoura A. Fukunaga M. Uesugi T. Tatsuoka Y. Horikawa A novel class of antagonists for metabotropic glutamate receptors, 7-(hydroxymino)cyclo-propa[b]chromen-lα-carboxylates Bioorg. Med. Chem. Lett. 6 1996 763 766
6. I. Aramori S. Nakanishi Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells Neuron 5 1992 757 765
7. I. Brabet S. Mary J. Bockaert J.P. Pin Phenyglycine derivatives discriminate between mGluRl-and mGluR5-mediated responses Neuropharmacol. 34 1995 895 904
8. V. Bruno G. Battaglia A. Copani R.G. Giffard G. Raciti R. Raffaele H. Shinozaki F. Nicoletti Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death Eur. J. Pharmacol. 256 1994 109 112
9. V. Bruno A. Copani T. Knopfel R. Kuhn G. Casabona Dell' P. Albani D.F. Condorelli F. Nicoletti Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells Neuropharmacol. 34 1995 1089 1098
10. V. Bruno G. Battaglia A. Copani R.G. Giffard G. Raciti R. Raffaele H. Shinozaki F. Nicoletti Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons aganist excitotoxic degeneration Eur. J. Neurosci 7 1995 1906 1913
11. V. Bruno A. Copani L. Bonanno T. Knoepfel R. Kuhn P.J. Roberts F. Nicoletti Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures Eur. J. Pharmacol. 310 1996 61 66
12. V. Bruno F.X. Sureda M. Storto G. Casabona A. Caruso T. Knopfel R. Kuhn F. Nicoletti The neuroprotective activity of group-II metaotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signalling J. Neurosci. 17 1997 1891 1897
13. Bruno B., Wroblewska J.T., Wroblewski L., Fiore F., Nicoletti 1997b Neuroprotective activity of N-acetylas-partylglutamate in cultured cortical cells. Neurosci. in press.
14. A. Buisson S. Yu D.W. Choi Role of metabotropic glutamate receptors in excitotoxic and apoptotic cell death Soc. Neurosci. Abstr. 20 1994 198.5
15. A. Buisson D.W. Choi The inhibitory mGluR agonist, S-4-carboxy-3-hydroxyphenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death Neuropharmacology 34 1995 1081 1087
16. A. Buisson S. Yu D.W. Choi DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxocity in cortical neurons Eur. J. Neurosci. 8 1996 138 143
17. J.J. Cha A. Talati J.A. Kerner R.A. Lichtenbaum A.B. Young Antisense oligonucleotides directed against mGluR5 glutamate receptor protect against malonic acid lesions in rat striatum Neuropharmacol. 35 A7 1996 28
18. D.W. Choi Excitotoxic cell death J. Neurobiol. 23 1992 1261 1276
19. P.J. Conn D.G. Winder R.W. Gereau IV Regulation of neuronal ciruits and animal behavior by metabotropic glutamate receptors P.J. Conn J. Patel The Metabotropic Glutamate Receptors 1994 Humana Press Inc. Totowa, NJ 195 229
20. F. Conquet Z.I. Bashir C.H. Davies H. Daniel F. Ferraguti F. Bordi K. Franz-Bacon A. Reggiani V. Matarese F. Conde G.L. Collingridge F. Crepel Motor deficit and impairment of synaptic plasticity in mice lacking mGluRl Nature 372 1994 237 243
21. A. Copani P.L. Canonico F. Nicoletti β-N-methylamino-L-alanine (L-BMAA) is a potent agonist of “metabolotropic” glutamate receptors Eur. J. Pharmacol. 181 1990 327 328
22. A. Copani V. Bruno G. Battaglia G. Leanza R. Pellitteri A. Russo A. Stanzani F. Nicoletti Activation of metabotropic glutamate receptors protects neurons against apoptosis induced by β-amyloid peptide Mol. Pharmacol. 47 1995 890 897
23. T.M. Dawson K. Hung V.L. Dawson J.P. Steiner S.H. Snyder Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase Ann. Neurol. 37 1995 115 118
24. V.L. Dawson T.M. Dawson Free radicals and neuronal cells death Cell Death Differ. 3 1996 71 78
25. V.L. Dawson T.M. Dawson E.D. London D.S. Bredt S.H. Snyder Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures Proc. Natl. Acad. Sci., USA 88 1991 6368 6371
26. M. Favaron H. Manev R. Siman Down regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death Proc. Natl. Acad. Sci. USA 87 1990 1983 1987
27. R.W. Gereau P.J. Conn Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1 J. Neurosci. 15 1995 6879 6889
28. I. Herrero E. Vazquez M.T. Miras-Portugal J. Sanchez-Prietro A decrease in [Ca2+]c but not in cAMP mediates the L-AP4 inhibition of glutamate release: PKC-mediated suppression of this inhibitory pathway Eur. J. Neurosci. 8 1996 700 709
29. K. Kaupmann K. Huggel J. Heid P.J. Flor S. Bishoff S.J. Mickel G. McMaster C. Angst M. Bittiger W. Froestl B. Bettler Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors Nature 386 1997 239 246
30. S. Kawabata R. Tsutsumi A. Kohara T. Yamaguchi S. Nakanishi M. Okada Control of calcium oscillations by posphorylation of metabotropic glutamate receptors Nature 383 1996 89 92
31. A.E. Kingston J.P. Burnett N.G. Mayne D. Lodge Pharmacological analysis of 4-carboxyphenylglycine derivatives: Comparison of effects on mGluR1a and mGluR5 subtypes Neuropharmacol. 34 1995 887 894
32. W.J. Koroshetz M.A. Moskowitz Emerging treatments for stroke in humans Trends Pharmacol. Sci. 17 1996 227 234
33. Kwak M., Ishida M., Miyamoto H., Shinozaki 1994 DCG-IV, a potent agonist for metabotropic receptors alleviates excitotoxin-induced neuronal damage in vivo. Abstract of the Ninth Rinshoken International Conference on Excitatory Amino Acid: Approaches to Clinical Use November 28–30, p. 16.
34. D.T. Loo Copani A. C.J. Pike E.R. Whittemore A.J. Walencewiczs C.W. Cotman Apoptosis is induced by β-amyloid in cultured central nervous system neurons Proc. Natl. Acad. Sci. USA 90 1993 7951 7955
35. Y.M. Lu Z. Jia C. Janus J.T. Henderson R. Gerlai J.M. Wojtowicz J.C. Roder Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP J. Neurosci. 17 1997 5196 5205
36. K. Maiese R. Greenberg L. Boccone M. Swiriduk Activation of metabotropic glutamate receptors is neuroprotective during nitric oxide toxicity in primary hippocampal neurons of rats Neurosci. Lett. 194 1995 173 176
37. M.P. Mattson M.A. Lowell K. Furukowa W.R. Markesberym Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons J. Neurochem. 65 1995 1740 1745
38. J.W. McDonald D.D. Schoepp The metabotropic excitatory amino acid receptor agonist, 1S.3R-ACPD selectively potentiates N -methyl-D-aspartate-induced brain injury Eur. J. Pharmacol. 215 1992 353 354
39. J.W. McDonald A.S. Fix J.P. Tizzano D.D. Schoepp Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist J. Neurosci. 13 1993 4445 4455
40. S. Miller C. Romano C.W. Cotman Growth factor up-regulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes J. Neurosci. 15 1995 6103 6109
41. C. Montoliu M. Llansola C. Cucarella S. Grisolia V. Felipo Activation of the metabotropic glutamate receptor mGluR5 prevents glutamate toxicity in primary cultures of cerebellar neurons J. Pharmacol. Exp. Ther. 281 1997 643 647
42. H. Monyer R.G. Giffard D.M. Hartley L.L. Dugan M.P. Goldberg D.W. Choi Oxygen and glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin Neuron 8 1992 967
43. F. Moroni A. Cozzi D. Pellegrini-Giampietro P. Leonardi S. Attucci F. Peruginelli G. Mannaioni R. Pellicciari Group 1 and group 2 metabotropic glutamate receptor agents: Pharmacological studies in vitro and in vivo The Journal of the European College of Neuropsychopharma-cology 7 suppl.2 1997 S95
44. S. Nakanishi Molecular diversity of glutamate receptors and implications for brain function Science 258 1992 597 603
45. S. Nakanishi Metabotropic glutamate receptor: Synaptic transmission modulation and plasticity Neuron 13 1994 1031 1037
46. D.W. Nicholson N.A. Thornberry Caspases: Killer proteases Trends Biochem. Sci. 22 1997 299 306
47. F. Nicoletti M.J. Iadarola J.T. Wroblewski E. Costa Excitatory amino acid recognition sitescoupled with inositol phospholipid metabolism: Developmental changes and interaction with αl-adrenoceptors Proc. Natl. Acad. Sci. USA 83 1986 1931 1935
48. Z. Nusser E. Mulvihill P. Treit P. Somogyi Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization Neuroscience 61 1994 421 427
49. L.R. Orlando D.G. Standaert J.-H. Cha J.B. Penney A.B. Young Metabotropic receptors in excitotoxicity: (S)-4C3HPG protects against striatal quinolinic acid lesions Soc. Neurosci. Abstr. 21 1995 529.19
50. D.E. Pellegrini-Giampietro R.S. Zukin M.V.L. Bennett S.L. Cho W.A. Pulsinelli Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats Proc. Natl. Acad. Sci. USA 89 1992 10499 10503
51. R. Pellicciari R. Luneia G. Costantino M. Marinozzi B. Natalini P. Jakobsen A. Kanstrup G. Lombardi F. Moroni C. Thomsen 1-Aminoindan-1,5-dicarboxylic acid, a novel antagonist at phospholipase C-linked metabotropic glutamate receptors J. Med. Chem. 38 1995 3717 3719
52. R.S. Petralia W.-X. Wang A.S. Niedzielski R.J. Wenthold The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations Neuroscience 71 1996 949 976
53. J.-P. Pin R. Duvoisin The metabotropic glutamate receptors: structure and functions Neuropharmacol. 34 1995 1 26
54. M. Pizzi C. Fallecara V. Arrighi M. Memo P.F. Spano Attenuation of excitatory amino acid toxicity by metabotropic glutalmate receptor agonists and aniracetam in primary cultures of cerebellar granule cells J. Neurochem. 61 1993 683 689
55. M. Pizzi O. Consolandi M. Memo P.F. Spano Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices Eur. J. Neurosci. 8 1996 1516 1521
56. T. Priestley E. Ochu J.A. Kemp Subtypes of NMDA receptor in neurons cultured from rat brain NeuroReport 5 1994 1763 1765
57. G. Riedel Function of metabotropic glutamate receptors in learning and memory Trends Neurosci. 19 1996 219 224
58. P.J. Roberts Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): Phenylglycine derivatives and other selective antagonists-an update Neuropharmacol. 34 1995 813 820
59. A.I. Sacaan D.D. Schoepp Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage Neurosci. Lett. 139 1992 79 82
60. D.D. Schoepp P.J. Conn Metabotropic glutamate receptors in brain function and pathology Trends Pharmacol. Sci. 14 1993 13 20
61. M.S. Seren C. Aldinio R. Zanoni A. Leon F. Nicoletti Stimulation of inositol phospholipid hydrolysis by excitatory amino acids is enhanced in brain slices from vulnerable regions after transient global ischaemia J. Neurochem. 53 1989 1700 1705
62. H. Shen J.A. Gorter E. Aronica X. Zheng L. Zhang M.V.L. Bennett R.S. Zukin Potentiation of NMDA responses by metabotropic receptor activation depends on NMDA receptor subunit composition Soc. Neurosci. Abstr. 21 1995 39.3
63. R. Shigemoto E. Wada H. Ohishi M. Takada M. Mizuno J.D.B. Roberts P. Somogyi Differential presynaptic localization of metabotropic glutamate receptor subtypes, mGluR2/3 and mGluR7 in the rat hippocampus Soc. Neurosci. Abstr. 21 1995 3380.20
64. R. Shigemoto A. Kulik J.D.B. Roberts H. Ohishi Z. Nusser T. Kaneko P. Somogyi Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone Nature 381 1996 523 525
65. P.S. Spencer P.B. Nunn J. Hugon A.C. Ludolph S.M. Ross D.N. Roy R.C. Robertson Guam amyotrophic lateral sclerosis: Dementia linked to a plant excitant neurotoxin Science 237 1987 517 522
66. S.A. Susin N. Zamzami M. Castedo E. Daugas H.-G. Wang S. Geley F. Fassy J. Reed G. Kroemer The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/ CD95-and ceramide-induced apoptosis J. Exp. Med. 1 1997 25 37
67. Y. Tanabe M. Masu I. Ishii R. Shigemoto N. Mizuno S. Nakanisgi A family of metabotropic receptord Neuron 8 1992 169 179
68. Y. Tanabe A. Nomura M. Masu R. Shigemoto N. Mizuno S. Nakanishi Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4 J. Neurosci. 13 1993 1372 1378
69. C. Thomsen V. Bruno F. Nicoletti M. Marinozzi R. Pellicciari (2S,1′S,2′S,3′R)-2-(2-carboxy-3′-phenyl-cyclopropyl)glycine, a potent and selective antagonist of type-2 metabotropic glutamate receptors Mol. Pharmacol. 50 1996 6 9
70. Toms P.J., Roberts 1997 Metabotropic glutamate receptors. 1997 Receptor & ion channel nomenclature supplement. Trends Pharmacol. Sci.
71. D.M. Turetsky A. Buisson D.M. Choi The metabotropic glutamate receptor agonist, 4C3HPG, reduces kainate-induced death of cortical neurons expressing calcium-permeable AMPA/kainate receptors Soc. Neurosci., Abstr. 21 1995 590.20
72. J.H. Weiss D.W. Choi β-N-methylamino-L-alanine neurotoxicity: Requirement for bicarbonate as a cofactor Science 241 1988 973 975
73. B. Wroblewska J.T. Wroblewski S. Pschenichkin A. Surin S.E. Sullivan J.H. Neale N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells J. Neurochem. 69 1997 174 181