-
1
-
-
0031035227
-
The structural basis of molecular genetic deletions. An integration of classical cytogenetic and molecular analyses in pancreatic adenocarcinoma
-
1 Brat DJ, Hahn SA, Griffin CA, Yeo CJ, Kern SE, Hruban RH: The structural basis of molecular genetic deletions. An integration of classical cytogenetic and molecular analyses in pancreatic adenocarcinoma. Am J Pathol 1997, 150:383-391.
-
(1997)
Am J Pathol
, vol.150
, pp. 383-391
-
-
Brat, D.J.1
Hahn, S.A.2
Griffin, C.A.3
Yeo, C.J.4
Kern, S.E.5
Hruban, R.H.6
-
2
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
-
2 Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, et al.: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994, 8:27-32.
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
-
3
-
-
0030030897
-
Immunohistochemical evaluation of HER-2/neu oncogene expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms
-
3 Day JD, DiGiuseppe JA, Yeo CJ, Loi-Goldman M, Anderson S, Kern SE, Hruban RH: Immunohistochemical evaluation of HER-2/neu oncogene expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms. Hum Pathol 1996, 27:119-124.
-
(1996)
Hum Pathol
, vol.27
, pp. 119-124
-
-
Day, J.D.1
Digiuseppe, J.A.2
Yeo, C.J.3
Loi-Goldman, M.4
Anderson, S.5
Kern, S.E.6
Hruban, R.H.7
-
4
-
-
0028305095
-
Overexpression of p53 protein in adenocarcinoma of the pancreas
-
4 DiGiuseppe JA, Hruban RH, Goodman SN, Polak M, van den Berg FM, Allison DC, et al.: Overexpression of p53 protein in adenocarcinoma of the pancreas. Am J Clin Pathol 1994, 101.684-688.
-
(1994)
Am J Clin Pathol
, vol.101
, pp. 684-688
-
-
DiGiuseppe, J.A.1
Hruban, R.H.2
Goodman, S.N.3
Polak, M.4
Van Den Berg, F.M.5
Allison, D.C.6
-
5
-
-
0028970946
-
p53-independent expression of the cyclin dependent kinase inhibitor p21 in pancreatic carcinoma
-
5 DiGiuseppe JA, Redston MS, Yeo CJ, Kern SE, Hruban RH: p53-independent expression of the cyclin dependent kinase inhibitor p21 in pancreatic carcinoma. Am J Pathol 1995, 147:884-888.
-
(1995)
Am J Pathol
, vol.147
, pp. 884-888
-
-
Digiuseppe, J.A.1
Redston, M.S.2
Yeo, C.J.3
Kern, S.E.4
Hruban, R.H.5
-
7
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
7 Hahn SA, Schutte M, Hoque ATMS, Moskaluk CA, daCosta LT, Rozenblum E, et al.: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996, 271:350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.M.S.3
Moskaluk, C.A.4
DaCosta, L.T.5
Rozenblum, E.6
-
8
-
-
0031909196
-
Genetics of pancreatic cancer: From genes to families
-
8 Hruban RH, Petersen GM, Ha PK, Kern SE: Genetics of pancreatic cancer: from genes to families. Surg Oncol Clin N Am 1998, 7:1-23. This is an extensive review on pancreatic cancer.
-
(1998)
Surg Oncol Clin N Am
, vol.7
, pp. 1-23
-
-
Hruban, R.H.1
Petersen, G.M.2
Ha, P.K.3
Kern, S.E.4
-
9
-
-
0027733796
-
K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
-
9 Hruban RH, van Mansfeld ADM, Offerhaus GJA, van Weering DHJ, Allison DC, Goodman SN, et al.: K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am J Pathol 1993, 143:545-554.
-
(1993)
Am J Pathol
, vol.143
, pp. 545-554
-
-
Hruban, R.H.1
Van Mansfeld, A.D.M.2
Offerhaus, G.J.A.3
Van Weering, D.H.J.4
Allison, D.C.5
Goodman, S.N.6
-
10
-
-
0028308492
-
p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
-
10 Redston MS, Caldas C, Seymour AB, Hruban RH, da Costa L, Yeo CJ. Kern SE: p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res 1994, 54:3025-3033.
-
(1994)
Cancer Res
, vol.54
, pp. 3025-3033
-
-
Redston, M.S.1
Caldas, C.2
Seymour, A.B.3
Hruban, R.H.4
Da Costa, L.5
Yeo, C.J.6
Kern, S.E.7
-
11
-
-
14444284330
-
Tumor-suppressive pathways in pancreatic carcinoma
-
11 Rozenblum E, Schutte M, Goggins M, Hahn SA, Panzer S, Zahurak M, et al.: Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res 1997, 57:1731-1734.
-
(1997)
Cancer Res
, vol.57
, pp. 1731-1734
-
-
Rozenblum, E.1
Schutte, M.2
Goggins, M.3
Hahn, S.A.4
Panzer, S.5
Zahurak, M.6
-
12
-
-
0029041032
-
Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region
-
12 Schutte M, daCosta LT, Hahn SA, Moskaluk CA, Hoque ATMS, Rozenblum E, et al.: Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region. Proc Natl Acad Sci U S A 1995, 92:5950-5954.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5950-5954
-
-
Schutte, M.1
DaCosta, L.T.2
Hahn, S.A.3
Moskaluk, C.A.4
Hoque, A.T.M.S.5
Rozenblum, E.6
-
13
-
-
16944367477
-
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas
-
13 Schutte M, Hruban RH, Geradts J, Maynard R, Hilgers W, Rabindran SK, et al.: Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. Cancer Res 1997, 57:3126-3130.
-
(1997)
Cancer Res
, vol.57
, pp. 3126-3130
-
-
Schutte, M.1
Hruban, R.H.2
Geradts, J.3
Maynard, R.4
Hilgers, W.5
Rabindran, S.K.6
-
14
-
-
0030962307
-
Gene expression profiles in normal and cancer cells
-
14 Zhang L, Zhou W, Velculescu VE, Kern SE, Hruban RH, Hamilton SR, et al.: Gene expression profiles in normal and cancer cells. Science 1997. 276:1268-1272.
-
(1997)
Science
, vol.276
, pp. 1268-1272
-
-
Zhang, L.1
Zhou, W.2
Velculescu, V.E.3
Kern, S.E.4
Hruban, R.H.5
Hamilton, S.R.6
-
15
-
-
0031595728
-
WAF1, and TGF-b1 in human ductal adenocarcinoma of the pancreas: TGF-β1 protein expression predicts longer survival
-
WAF1, and TGF-b1 in human ductal adenocarcinoma of the pancreas: TGF-β1 protein expression predicts longer survival. Am J Clin Pathol 1998, 110:16-23.
-
(1998)
Am J Clin Pathol
, vol.110
, pp. 16-23
-
-
Coppola, D.1
Lu, L.2
Fruehauf, J.P.3
Kyshtoobayeva, A.4
Karl, R.C.5
Nicosia S. V6
Yeatman, T.J.7
-
16
-
-
0031884433
-
Genetic alterations in chronic pancreatitis: Evidence for early occurrence of p53 but not K-ras mutations
-
16 Gansauge S, Schmid RM, Muller J, Adler G, Mattfeld T, Beger HG: Genetic alterations in chronic pancreatitis: evidence for early occurrence of p53 but not K-ras mutations. Br J Surg 1938, 85:337-340.
-
(1938)
Br J Surg
, vol.85
, pp. 337-340
-
-
Gansauge, S.1
Schmid, R.M.2
Muller, J.3
Adler, G.4
Mattfeld, T.5
Beger, H.G.6
-
17
-
-
12644253827
-
Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
-
17 Goggins M, Schutte M, Lu J, Moskaluk CA, Weinstein CL, Petersen GM, et al.: Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res 1996, 56:5360-5364.
-
(1996)
Cancer Res
, vol.56
, pp. 5360-5364
-
-
Goggins, M.1
Schutte, M.2
Lu, J.3
Moskaluk, C.A.4
Weinstein, C.L.5
Petersen, G.M.6
-
18
-
-
0031812131
-
Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival
-
18 Kommann M, Ishiwata T, Itakura J, Tangvoranuntakul P, Beger HG, Korc M: Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival. Oncology 1998, 55:363-369.
-
(1998)
Oncology
, vol.55
, pp. 363-369
-
-
Kommann, M.1
Ishiwata, T.2
Itakura, J.3
Tangvoranuntakul, P.4
Beger, H.G.5
Korc, M.6
-
19
-
-
0031863603
-
An immunohistochemical study of bcl-2 and p53 protein expression in pancreatic carcinomas
-
19 Ohshio G, Suwa H, Imamura T, Yamaki K, Tanaka T, Hashimoto Y, Imamura M: An immunohistochemical study of bcl-2 and p53 protein expression in pancreatic carcinomas. Scand J Gastroenterol 1998, 33:535-539.
-
(1998)
Scand J Gastroenterol
, vol.33
, pp. 535-539
-
-
Ohshio, G.1
Suwa, H.2
Imamura, T.3
Yamaki, K.4
Tanaka, T.5
Hashimoto, Y.6
Imamura, M.7
-
20
-
-
0031860052
-
Molecular analysis of the p53 gene in pancreatic adenocarcinoma
-
20 Yiwei L, Bhuiyan M, Vaitkevicius VK, Sarkar FH: Molecular analysis of the p53 gene in pancreatic adenocarcinoma. Diagn Mol Pathol 1998, 7:4-9.
-
(1998)
Diagn Mol Pathol
, vol.7
, pp. 4-9
-
-
Yiwei, L.1
Bhuiyan, M.2
Vaitkevicius, V.K.3
Sarkar, F.H.4
-
21
-
-
0030687903
-
Molecular advances in pancreatic cancer
-
21 Lemoine NR: Molecular advances in pancreatic cancer. Digestion 1997, 58:550-556.
-
(1997)
Digestion
, vol.58
, pp. 550-556
-
-
Lemoine, N.R.1
-
22
-
-
0032404111
-
Genetic alterations of the transforming growth factor β receptor genes in pancreatic and biliary adenocarcinomas
-
22 Goggins M, Shekher M, Kenan T, Yeo CJ, Hruban RH, Kern SE: Genetic alterations of the transforming growth factor β receptor genes in pancreatic and biliary adenocarcinomas. Cancer Res 1998, 58:5329-5332.
-
(1998)
Cancer Res
, vol.58
, pp. 5329-5332
-
-
Goggins, M.1
Shekher, M.2
Kenan, T.3
Yeo, C.J.4
Hruban, R.H.5
Kern, S.E.6
-
23
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
23 Jenne DE, Reimann H, Nezu J, Friedel W, Loff S, Jeschke R, et al: Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 1998, 18:38-43.
-
(1998)
Nat Genet
, vol.18
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
-
24
-
-
0032100617
-
Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor-suppressor gene
-
24 Su GH, Hilgers W, Shekher M, Tang D, Yeo CJ, Hruban RH, Kern SE: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor-suppressor gene. Cancer Res 1998, 58:2339-2342.
-
(1998)
Cancer Res
, vol.58
, pp. 2339-2342
-
-
Su, G.H.1
Hilgers, W.2
Shekher, M.3
Tang, D.4
Yeo, C.J.5
Hruban, R.H.6
Kern, S.E.7
-
25
-
-
0032984141
-
Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
-
25 Su GH, Hruban RH, Bansal RK, Bova GS, Tang DT, Shekher MC, et al.: Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. Am J Pathol 1999, 154:1835-1840. This paper shows that the Peutz-Jeghers gene plays a role in the development of pancreatic cancer.
-
(1999)
Am J Pathol
, vol.154
, pp. 1835-1840
-
-
Su, G.H.1
Hruban, R.H.2
Bansal, R.K.3
Bova, G.S.4
Tang, D.T.5
Shekher, M.C.6
-
26
-
-
0031981181
-
Novel mutations in the polyadenine tract of the transforming growth factor β type II receptor gene are found in a subpopulation of human pancre atic carcinomas
-
26 Venkatasubbarao K, Ahmed MM, Swiderski C, Harp C, Lee EY, McGarth P, et al.: Novel mutations in the polyadenine tract of the transforming growth factor β type II receptor gene are found in a subpopulation of human pancre atic carcinomas. Genes Chromosom Cancer 1998, 22:138-144.
-
(1998)
Genes Chromosom Cancer
, vol.22
, pp. 138-144
-
-
Venkatasubbarao, K.1
Ahmed, M.M.2
Swiderski, C.3
Harp, C.4
Lee, E.Y.5
McGarth, P.6
-
27
-
-
7844240481
-
Disruption of the antiproliferative TGF-β signaling pathways in human pancreatic cancer cells
-
27 Villanueva A, Garcia C, Paules AB, Vicente M, Megias M, Reyes G, et al.: Disruption of the antiproliferative TGF-β signaling pathways in human pancreatic cancer cells. Oncogene 1998, 17:1969-1978.
-
(1998)
Oncogene
, vol.17
, pp. 1969-1978
-
-
Villanueva, A.1
Garcia, C.2
Paules, A.B.3
Vicente, M.4
Megias, M.5
Reyes, G.6
-
28
-
-
0031694080
-
Transfection of the type 1 TGF-β receptor restores TGF-β responsiveness in pancreatic cancer
-
28 Wagner M, Kleeff J, Lopez ME, Bookman I, Massaqué J, Korc M: Transfection of the type 1 TGF-β receptor restores TGF-β responsiveness in pancreatic cancer. Int J Cancer 1998, 78:255-260.
-
(1998)
Int J Cancer
, vol.78
, pp. 255-260
-
-
Wagner, M.1
Kleeff, J.2
Lopez, M.E.3
Bookman, I.4
Massaqué, J.5
Korc, M.6
-
29
-
-
0030757691
-
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
-
29 Teng DHF, Perry WL, Hogan JK, Baumgard M, Bell R, Berry S, et al.: Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. Cancer Res 1997, 57:4177-4182.
-
(1997)
Cancer Res
, vol.57
, pp. 4177-4182
-
-
Teng, D.H.F.1
Perry, W.L.2
Hogan, J.K.3
Baumgard, M.4
Bell, R.5
Berry, S.6
-
30
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz Jeghers syndrome
-
30 Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, et al.: A serine/threonine kinase gene defective in Peutz Jeghers syndrome. Nature 1998, 391:184-187.
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
-
31
-
-
0031012344
-
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
-
31 Hemminki A, Tomlinson I, Markie D. Jarvinen H, Sistonen P, Bjorkqvist AM, et al.: Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 1997, 15:87-90.
-
(1997)
Nat Genet
, vol.15
, pp. 87-90
-
-
Hemminki, A.1
Tomlinson, I.2
Markie, D.3
Jarvinen, H.4
Sistonen, P.5
Bjorkqvist, A.M.6
-
32
-
-
0023192463
-
Increased risk of cancer in the Peutz-Jeghers syndrome
-
32 Giardiello FM, Welsh SB, Hamilton SR, Offerhaus GJA, Gittelsohn AM, Booker SV, et al.: Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med 1987, 316:1511-1514.
-
(1987)
N Engl J Med
, vol.316
, pp. 1511-1514
-
-
Giardiello, F.M.1
Welsh, S.B.2
Hamilton, S.R.3
Offerhaus, G.J.A.4
Gittelsohn, A.M.5
Booker, S.V.6
-
33
-
-
0021879645
-
Hereditary cancer, oncogenes, and antioncogenes
-
33 Knudson AG: Hereditary cancer, oncogenes, and antioncogenes. Cancer Res 1985, 45:1437-1443.
-
(1985)
Cancer Res
, vol.45
, pp. 1437-1443
-
-
Knudson, A.G.1
-
34
-
-
0029919109
-
Hereditary cancer: Two hits revisited
-
34 Knudson AG: Hereditary cancer: two hits revisited. J Cancer Res Clin Oncol 1996, 122:135-140.
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 135-140
-
-
Knudson, A.G.1
-
35
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
35 Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK, Testa JR: Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci U S A 1996, 93:3636-3641.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
Sonoda, G.4
Altomare, D.A.5
Watson, D.K.6
Testa, J.R.7
-
36
-
-
0030598884
-
Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer
-
36 Miwa W, Yasuda J, Murakami Y, Yashima K, Sugano K, Sekine T, et al.: Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer. Biomed Biophys Res Commun 1996, 225:968-974.
-
(1996)
Biomed Biophys Res Commun
, vol.225
, pp. 968-974
-
-
Miwa, W.1
Yasuda, J.2
Murakami, Y.3
Yashima, K.4
Sugano, K.5
Sekine, T.6
-
37
-
-
0031936947
-
Amplification and overexpression of the AK12 oncogene in a subset of human pancreatic ductal adenocarcinomas
-
37 Ruggeri BA, Huang L, Wood M, Cheng JQ, Testa JR: Amplification and overexpression of the AK12 oncogene in a subset of human pancreatic ductal adenocarcinomas. Mol Carcinog 199S, 21:81 -86.
-
(1995)
Mol Carcinog
, vol.21
, pp. 81-86
-
-
Ruggeri, B.A.1
Huang, L.2
Wood, M.3
Cheng, J.Q.4
Testa, J.R.5
-
38
-
-
0344097450
-
Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas
-
38 Ghadimi BM, Schröck E, Walker RL, Wangsa D, Jauho A, Meltzer PS, Ried T: Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas. Am J Pathol 1999, 154:525-536.
-
(1999)
Am J Pathol
, vol.154
, pp. 525-536
-
-
Ghadimi, B.M.1
Schröck, E.2
Walker, R.L.3
Wangsa, D.4
Jauho, A.5
Meltzer, P.S.6
Ried, T.7
-
39
-
-
0029066689
-
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability
-
39 Markowitz S, Wang J, Myeroff L, Parsons R, Sun LZ, Lutterbaugh J, et al.: Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science 1995, 268:1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
Parsons, R.4
Sun, L.Z.5
Lutterbaugh, J.6
-
40
-
-
0031818750
-
Mutated ras peptides as vaccines in immunotherapy of cancer
-
40 Gjertsen MK, Gaudernack G: Mutated ras peptides as vaccines in immunotherapy of cancer. Vox Sang 1998, 74:489-495. This paper describes a novel vaccine that uses mutant K-ras to treat pancreatic cancers.
-
(1998)
Vox Sang
, vol.74
, pp. 489-495
-
-
Gjertsen, M.K.1
Gaudernack, G.2
-
41
-
-
0033521860
-
Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated k-ras genes
-
41 Kita K, Saito S, Morioka CY, Watanabe A: Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated k-ras genes. Int J Cancer 1999, 80:553-558.
-
(1999)
Int J Cancer
, vol.80
, pp. 553-558
-
-
Kita, K.1
Saito, S.2
Morioka, C.Y.3
Watanabe, A.4
-
42
-
-
13144260677
-
Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type k-ras oncogene has different effects on protein phosphorylation and induction of apoptosis
-
42 Müller C, Bockhorn AG, Klusmeier S, Kiehl M, Roeder C, Kalthoff H, Koch OM: Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type k-ras oncogene has different effects on protein phosphorylation and induction of apoptosis. Int J Oncol 1998, 12:717-723. This new class of drugs may be useful in the treatment of pancreatic cancer.
-
(1998)
Int J Oncol
, vol.12
, pp. 717-723
-
-
Müller, C.1
Bockhorn, A.G.2
Klusmeier, S.3
Kiehl, M.4
Roeder, C.5
Kalthoff, H.6
Koch, O.M.7
-
43
-
-
0030724514
-
Molecular versus conventional markers in pancreatic cancer
-
43 Friess H, Kleef J, Gumbs A, Büchler MW: Molecular versus conventional markers in pancreatic cancer. Digestion 1997, 58:557-563.
-
(1997)
Digestion
, vol.58
, pp. 557-563
-
-
Friess, H.1
Kleef, J.2
Gumbs, A.3
Büchler, M.W.4
-
44
-
-
0028301905
-
Molecular biology and the early detection of carcinoma of the bladder the case of Hubert H. Humphrey
-
44 Hrubao RH, van der Riel P, Erozan Y, Sidransky D: Molecular biology and the early detection of carcinoma of the bladder the case of Hubert H. Humphrey. N Engl J Med 1994, 330:1276-1278.
-
(1994)
N Engl J Med
, vol.330
, pp. 1276-1278
-
-
Hrubao, R.H.1
Van Der Riel, P.2
Erozan, Y.3
Sidransky, D.4
-
45
-
-
0031666927
-
K-ras mutations in stools and tissue samples from patients with malignant and nonmalignant pancreatic diseases
-
45 Berndt C, Haubold K, Wenger F, Brux B, Müller J, Bendzko P, el al.: K-ras mutations in stools and tissue samples from patients with malignant and nonmalignant pancreatic diseases. Clin Chem 1998, 44:2103-2107.
-
(1998)
Clin Chem
, vol.44
, pp. 2103-2107
-
-
Berndt, C.1
Haubold, K.2
Wenger, F.3
Brux, B.4
Müller, J.5
Bendzko, P.6
-
46
-
-
0028342395
-
Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia
-
46 Caldas C, Hahn SA, Hruban RH, Redston MS, Yeo CJ, Kern SE: Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. Cancer Res 1994, 54:3568-3573.
-
(1994)
Cancer Res
, vol.54
, pp. 3568-3573
-
-
Caldas, C.1
Hahn, S.A.2
Hruban, R.H.3
Redston, M.S.4
Yeo, C.J.5
Kern, S.E.6
-
47
-
-
0031815875
-
Cell-free DNA in human blood plasma: Length measurements in patients with pancreatic cancer and healthy controls
-
47 Giacona MB, Ruben GC, Iczkowski KA, Roos TB, Porter DM, Sorenson GD: Cell-free DNA in human blood plasma: length measurements in patients with pancreatic cancer and healthy controls. Pancreas 1998, 17:89-97.
-
(1998)
Pancreas
, vol.17
, pp. 89-97
-
-
Giacona, M.B.1
Ruben, G.C.2
Iczkowski, K.A.3
Roos, T.B.4
Porter, D.M.5
Sorenson, G.D.6
-
48
-
-
0032148160
-
A case of small pancreatic cancer diagnosed by serial follow-up studies promptly by a positive K-ras point mutation in pure pancreatic juice
-
48 Ochi K, Hasuoka H, Mizushima T, Matsumura N, Harada H: A case of small pancreatic cancer diagnosed by serial follow-up studies promptly by a positive K-ras point mutation in pure pancreatic juice. Am J Gastroenterol 1998, 93:1366-1368.
-
(1998)
Am J Gastroenterol
, vol.93
, pp. 1366-1368
-
-
Ochi, K.1
Hasuoka, H.2
Mizushima, T.3
Matsumura, N.4
Harada, H.5
-
49
-
-
0031813507
-
Detection of ras gene mutations in peripheral blood of carcinoma patients using CD45 immunomagnetic separation and nested mutant allele specific amplification
-
49 Shibata K, Mori M, Kitano S, Akiyoshi T: Detection of ras gene mutations in peripheral blood of carcinoma patients using CD45 immunomagnetic separation and nested mutant allele specific amplification. Int J Oncol 1998, 12:1333-1338.
-
(1998)
Int J Oncol
, pp. 1333-1338
-
-
Shibata, K.1
Mori, M.2
Kitano, S.3
Akiyoshi, T.4
-
50
-
-
0031892411
-
Quantitative analysis of ras gene mutation in pancreatic juice for diagnosis of pancreatic adenocarcinoma
-
50 Iada M, Ieratani T, Komatsu Y, Kawabe T, Shiratori Y, Omata M: Quantitative analysis of ras gene mutation in pancreatic juice for diagnosis of pancreatic adenocarcinoma. Dig Dis Sci 1998, 43:15-20.
-
(1998)
Dig Dis Sci
, vol.43
, pp. 15-20
-
-
Iada, M.1
Ieratani, T.2
Komatsu, Y.3
Kawabe, T.4
Shiratori, Y.5
Omata, M.6
-
51
-
-
0031893736
-
K-ras mutations in the duodenal fluid of patients with pancreatic carcinoma
-
51 Wilentz RE, Chung CH, Sturm PDJ, Musler A, Sohn TA, Offerhaus GJA, et al.: K-ras mutations in the duodenal fluid of patients with pancreatic carcinoma. Cancer 1998, 82:96-103.
-
(1998)
Cancer
, vol.82
, pp. 96-103
-
-
Wilentz, R.E.1
Chung, C.H.2
Sturm, P.D.J.3
Musler, A.4
Sohn, T.A.5
Offerhaus, G.J.A.6
-
52
-
-
17344377380
-
Detection of K-ras gene mutations in plasma DNA of patients with pancreatic adenocarcinoma: Correlation with clinicopathological features
-
52 Yamada T, Nakamori S, Ohzato H, Oshima S, Aoki T, Higaki N, et al.: Detection of K-ras gene mutations in plasma DNA of patients with pancreatic adenocarcinoma: correlation with clinicopathological features. Clin Cancer Res 1998, 4:1527-1532.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1527-1532
-
-
Yamada, T.1
Nakamori, S.2
Ohzato, H.3
Oshima, S.4
Aoki, T.5
Higaki, N.6
-
53
-
-
0032190218
-
Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis
-
53 Fukushige S, Furukawa T, Satoh K, Sunamura M, Koizumi M, Horii A: Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis. Cancer Res 1998, 58:4223-4226.
-
(1998)
Cancer Res
, vol.58
, pp. 4223-4226
-
-
Fukushige, S.1
Furukawa, T.2
Satoh, K.3
Sunamura, M.4
Koizumi, M.5
Horii, A.6
-
54
-
-
0031015729
-
Telomerase activity is detected in pancreatic cancer but not in benign tumors
-
54 Hiyama E, Kodama T, Shinbara K, Iwao T, Itoh M, Hiyama K, et al.: Telomerase activity is detected in pancreatic cancer but not in benign tumors. Cancer Res 1997, 57:326-331.
-
(1997)
Cancer Res
, vol.57
, pp. 326-331
-
-
Hiyama, E.1
Kodama, T.2
Shinbara, K.3
Iwao, T.4
Itoh, M.5
Hiyama, K.6
-
55
-
-
0030715607
-
Telomerase activity for the preoperative diagnosis of pancreatic cancer
-
55 Iwao I, Hiyama E, Yokoyama T, Tsuchida A, Hiyama K, Murakami Y, et al.: Telomerase activity for the preoperative diagnosis of pancreatic cancer. J Natl Cancer Inst 1997, 89:1621 -1623.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1621-1623
-
-
Iwao, I.1
Hiyama, E.2
Yokoyama, T.3
Tsuchida, A.4
Hiyama, K.5
Murakami, Y.6
-
56
-
-
0031043998
-
Telomerase in the early detection of cancer
-
56 Shay JW, Gazdar AF: Telomerase in the early detection of cancer. J Clin Pathol 1997, 50:106-109.
-
(1997)
J Clin Pathol
, vol.50
, pp. 106-109
-
-
Shay, J.W.1
Gazdar, A.F.2
-
57
-
-
0032431630
-
Telomerase activity detected in pancreatic juice 19 months before a tumor is detected in a patient with pancreatic cancer
-
57 Suehara N, Mizumoto K, Kusumoto M, Niiyama H, Ogawa T, Yamaguchi K, et al.: Telomerase activity detected in pancreatic juice 19 months before a tumor is detected in a patient with pancreatic cancer. Am J Gastroenterol 1997, 93:1967-1971.
-
(1997)
Am J Gastroenterol
, vol.93
, pp. 1967-1971
-
-
Suehara, N.1
Mizumoto, K.2
Kusumoto, M.3
Niiyama, H.4
Ogawa, T.5
Yamaguchi, K.6
-
58
-
-
0030693253
-
Increased telomerase activities in human pancreatic duct adenocarcinomas
-
58 Tsutsumi M, Tsujiuchi T, Ishikawa O, Majima T, Yoshimoto T, Sasaki Y, et al.: Increased telomerase activities in human pancreatic duct adenocarcinomas. Jpn J Cancer Res 1997, 88:971-976.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 971-976
-
-
Tsutsumi, M.1
Tsujiuchi, T.2
Ishikawa, O.3
Majima, T.4
Yoshimoto, T.5
Sasaki, Y.6
-
59
-
-
0028789793
-
Serial analysis of gene expression
-
59 Velculescu VE, Zhang L, Vogelstein B, Kinzler KW: Serial analysis of gene expression. Science 1995, 270:484-487.
-
(1995)
Science
, vol.270
, pp. 484-487
-
-
Velculescu, V.E.1
Zhang, L.2
Vogelstein, B.3
Kinzler, K.W.4
-
60
-
-
6844257540
-
Identifying markers for pancreatic cancer by gene expression analysis
-
60 Zhou W, Sokoll LJ, Bruzek DJ, Zhang L, Velculescu VE, Goldin SB, et al.: Identifying markers for pancreatic cancer by gene expression analysis. Cancer Epidemiol Biomarkers Prev 1998, 7:109-112. This paper demonstrates the development of a new screening test for pancreatic cancer that uses serial analysis of gene expression.
-
(1998)
Cancer Epidemiol Biomarkers Prev
, vol.7
, pp. 109-112
-
-
Zhou, W.1
Sokoll, L.J.2
Bruzek, D.J.3
Zhang, L.4
Velculescu, V.E.5
Goldin, S.B.6
-
61
-
-
0032807116
-
Familial pancreatic cancer
-
in press
-
61 Hruban RH, Petersen GM, Goggins M, Tersmette AC, Offerhaus GJA, Falatko F, Kern SE: Familial pancreatic cancer. Ann Oncol 1999, in press.
-
Ann Oncol 1999
-
-
Hruban, R.H.1
Petersen, G.M.2
Goggins, M.3
Tersmette, A.C.4
Offerhaus, G.J.A.5
Falatko, F.6
Kern, S.E.7
-
62
-
-
0029944668
-
Familial pancreatic cancer: A review
-
62 Lynch HT, Smyrk T, Kern SE, Hruban RH, Lightdale CJ, Lemon SJ, et al.: Familial pancreatic cancer: a review. Semin Oncol 1996, 23:251-275.
-
(1996)
Semin Oncol
, vol.23
, pp. 251-275
-
-
Lynch, H.T.1
Smyrk, T.2
Kern, S.E.3
Hruban, R.H.4
Lightdale, C.J.5
Lemon, S.J.6
-
63
-
-
0032471191
-
K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas
-
63 Bartsch D, Bastian D, Barth P, Schudy A, Nies C, Kisker C, et al.: K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas. Ann Surg 1998, 228:79-86.
-
(1998)
Ann Surg
, vol.228
, pp. 79-86
-
-
Bartsch, D.1
Bastian, D.2
Barth, P.3
Schudy, A.4
Nies, C.5
Kisker, C.6
-
64
-
-
0031947841
-
Analysis of K-ras oncogene mutation directly applied to atypical cell clusters on cytologic smear slides of bile and pancreatic juice
-
64 Fukushima N, Suzuki M, Fukayama M; Analysis of K-ras oncogene mutation directly applied to atypical cell clusters on cytologic smear slides of bile and pancreatic juice. Pathol Int 1998, 48:33-40.
-
(1998)
Pathol Int
, vol.48
, pp. 33-40
-
-
Fukushima, N.1
Suzuki, M.2
Fukayama, M.3
-
65
-
-
0031861172
-
Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials
-
65 Jaffce EM, Schutte M, Gossett J, Morsberger LA, Adler AJ, Thomas M, et al.: Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials. Cancer J Sci Am 1998, 4:194-203. This paper describes the development of an exciting new vaccine for the treatment of pancreatic cancer.
-
(1998)
Cancer J Sci Am
, vol.4
, pp. 194-203
-
-
Jaffce, E.M.1
Schutte, M.2
Gossett, J.3
Morsberger, L.A.4
Adler, A.J.5
Thomas, M.6
-
66
-
-
7844240884
-
K-ras gene mutations in the diagnosis of fine-needle aspirates of pancreatic masses: Prospective study using two techniques with different detection limits
-
66 Mora J, Puig P, Boadas J, Urgell E, Montserrat E, Lerma E, et al.: K-ras gene mutations in the diagnosis of fine-needle aspirates of pancreatic masses: prospective study using two techniques with different detection limits. Clin Chem 1998, 44:2243-2248.
-
(1998)
Clin Chem
, vol.44
, pp. 2243-2248
-
-
Mora, J.1
Puig, P.2
Boadas, J.3
Urgell, E.4
Montserrat, E.5
Lerma, E.6
-
67
-
-
0031683984
-
K-ras oncogene mutations in osteoclast-like giant-cell tumors of the pancreas and liver; genetic evidence to support origin from the duct epithelium
-
67 Westra WH, Sturm PJ, Drillenburg P, Choti MA, Klimstra DS, Abores-Saavedra J, et al.: K-ras oncogene mutations in osteoclast-like giant-cell tumors of the pancreas and liver; genetic evidence to support origin from the duct epithelium. Am J Surg Pathol 1998, 22:1247-1254.
-
(1998)
Am J Surg Pathol
, vol.22
, pp. 1247-1254
-
-
Westra, W.H.1
Sturm, P.J.2
Drillenburg, P.3
Choti, M.A.4
Klimstra, D.S.5
Abores-Saavedra, J.6
-
68
-
-
0031807209
-
Detection of K-ras point mutations in the supernatants of peritoneal and pleural effusions for diagnosis complementary to cytologic examination
-
68 Yamashita K, Kuba T, Shinoda H, Takahashi E, Okayasu I: Detection of K-ras point mutations in the supernatants of peritoneal and pleural effusions for diagnosis complementary to cytologic examination. Am J Clin Pathol 1998, 109:704-711.
-
(1998)
Am J Clin Pathol
, vol.109
, pp. 704-711
-
-
Yamashita, K.1
Kuba, T.2
Shinoda, H.3
Takahashi, E.4
Okayasu, I.5
-
69
-
-
0031757005
-
The potential diagnostic use of k-ras codon 12 and p53 alterations in brush cytology from the pancreatic head region
-
69 Sturm PDJ, Hruban RH, Ramsoekh TB, Noorduyn LA, Tytgat GNJ, Gouma DJ, Offerhaus GJA: The potential diagnostic use of k-ras codon 12 and p53 alterations in brush cytology from the pancreatic head region. J Pathol 1998, 186:247-253.
-
(1998)
J Pathol
, vol.186
, pp. 247-253
-
-
Sturm, P.D.J.1
Hruban, R.H.2
Ramsoekh, T.B.3
Noorduyn, L.A.4
Tytgat, G.N.J.5
Gouma, D.J.6
Offerhaus, G.J.A.7
-
70
-
-
17344374264
-
A phase I clinical trial of lethally irradiated allogeneic pancreatic tumor cells transfected with the GM-CSF gene for the treatment of pancreatic adenocarcinoma
-
70 Jaffee EM; A phase I clinical trial of lethally irradiated allogeneic pancreatic tumor cells transfected with the GM-CSF gene for the treatment of pancreatic adenocarcinoma. Hum Gene Ther 1998, 9:1951-1971.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1951-1971
-
-
Jaffee, E.M.1
-
71
-
-
0032126029
-
Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells
-
71 Abbott DW, Freeman ML, Holt, JT: Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells. J Natl Cancer Inst 1998, 90:978-985. This article suggests that cancers with BRCA2 mutations may be more sensitive to radiation.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 978-985
-
-
Abbott, D.W.1
Freeman, M.L.2
Holt, J.T.3
-
72
-
-
0031137173
-
Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients
-
72 Ozcelik H, Schmocker B, DiNicola N, Shi XH, Langer B, Moore M, et al.: Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients. Nat Genet 1997, 16:17-18.
-
(1997)
Nat Genet
, vol.16
, pp. 17-18
-
-
Ozcelik, H.1
Schmocker, B.2
Dinicola, N.3
Shi, X.H.4
Langer, B.5
Moore, M.6
|