A case of small pancreatic cancer diagnosed by serial follow-up studies promptly by a positive K-ras point mutation in pure pancreatic juice

American Journal of Gastroenterology

Volumn 93, Issue 8, 1998, Pages 1366-1368

  Ochi, Koji ^a   Hasuoka, Hideaki ^a   Mizushima, Takaaki ^a   Matsumura, Naoki ^a   Harada, Hideo ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CASE REPORT; CELL HYPERPLASIA; CODON; DIAGNOSTIC APPROACH ROUTE; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PANCREAS DUCT; PANCREAS RESECTION; PANCREAS SECRETION; POINT MUTATION; PRIORITY JOURNAL;

ADENOCARCINOMA; AGED; CODON; FEMALE; FOLLOW-UP STUDIES; GENES, RAS; HUMANS; PANCREATECTOMY; PANCREATIC JUICE; PANCREATIC NEOPLASMS; POINT MUTATION; SPLENECTOMY;

EID: 0032148160     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1572-0241.1998.419_W.x     Document Type: Article

References (16)

1. 1. Tada M, Omata M, Ohto M. Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma. Gastroenterology 1991; 100:233-8.
2. 2. Tada M, Omata M, Ohto M. Ras gene mutation in intraductal papillary neoplasms of the pancreas. Cancer 1991;67:634-7.
3. 3. Yanagisawa A, Kato Y, Ohtake K, et al. c-Ki-ras point mutations in ductectatic-type mucinous cystic neoplasms of the pancreas. Jpn J Cancer Res 1991;82:1057-60.
4. 4. Yanagisawa A, Ohtake K, Ohashi K, et al. Frequent c-Ki-ras oncogene activation in mucinous cell hyperplasia of pancreas suffering from chronic inflammation. Cancer Res 1993;53:953-6.
5. 5. Pasricha P.J. ERCP meets C-K-ras towards an improved diagnosis of pancreatic cancer. Gastroenterology 1996;110:310-7.
6. 6. Matsumoto S, Harada H, Tanaka J, et al. Evaluation of cytology and tumor markers of pure pancreatic juice for the diagnosis of pancreatic cancer at early stages. Pancreas 1994;5:741-7.
7. 7. Nakaizumi A, Tatsuta M, Uehara H, et al. Cytologic examination of pure pancreatic juice in the diagnosis of pancreatic carcinoma. The endoscopic retrograde intraductal catheter aspiration cytologic technique. Cancer 1992;70:2610-4.
8. 8. Gansauge S, Gansauge F, Beger HG. Molecular oncology in pancreatic cancer. J Mol Med 1996;74:313-20.
9. 9. Schaeffer BK, Glasner S, Kuhlmann E, et al. Mutated c-K-ras in small pancreatic adenocarcinoma. Pancreas 1994;9:161-5.
10. 10. Berthelemy P, Bouisson M, Escourrou J, et al. Identification of K-ras mutations in pancreatic juice in the early diagnosis of pancreatic cancer. Ann Intern Med 1995;123:188-91.
11. 11. Wakabayashi T, Sawabu N, Watanabe H, et al. Detection of K-ras point mutation at codon 12 in pure pancreatic juice collected 3 years and 6 months before the clinical diagnosis of pancreatic cancer. Am J Gastroenterol 1996;91:1848-51.
12. 12. Watanabe H, Sawabu N, Songur Y, et al. Detection of K-ras point mutation at codon 12 in pure pancreatic juice for the diagnosis of pancreatic cancer by PCR-RFLP analysis. Pancreas 1996;12:18-24.
13. 13. Caldas C, Hahn SA, Hruban RH, et al. Detection of K-ras mutation in the stool of patients with pancreatic adenocarcinoma and pancreatic duct hyperplasia. Cancer Res 1994;54:3568-73.
14. 14. Tada M, Ohashi M, Shiratori Y, et al. Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease. Gastroenterology 1996;110:227-31.
15. 15. Cerny ML, Mangold KA, Scarpelli DG. K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster. Cancer Res 1992;52:4507-13.
16. 16. Chang KJ, Albers CG, Erickson RA, et al. Endoscopic ultrasound-guided fine needle aspiration of pancreatic carcinoma. Am J Gastroenterol 1994;89:263-6.