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Volumn 74, Issue SUPPL. 2, 1998, Pages 489-495

Mutated ras peptides as vaccines in immunotherapy of cancer

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; PROTEIN P21; RAS PROTEIN;

EID: 0031818750     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1423-0410.1998.tb05462.x     Document Type: Conference Paper
Times cited : (30)

References (49)
  • 1
    • 0014887939 scopus 로고
    • The concept of immunological surveillance
    • Burnet FM. The concept of immunological surveillance. Prog Exp Tumor Res. 1970. 13: 1.
    • (1970) Prog Exp Tumor Res , vol.13 , pp. 1
    • Burnet, F.M.1
  • 3
    • 0030347502 scopus 로고    scopus 로고
    • Identification of the genes encoding cancer antigens: Implications for cancer immunotherapy
    • Rosenberg SA, Kawakami Y, Robbins PF, Wang R. Identification of the genes encoding cancer antigens: Implications for cancer immunotherapy. Adv Cancer Res. 1996. 70: 145.
    • (1996) Adv Cancer Res , vol.70 , pp. 145
    • Rosenberg, S.A.1    Kawakami, Y.2    Robbins, P.F.3    Wang, R.4
  • 7
    • 0026564444 scopus 로고
    • Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln→Leu61)
    • Gedde-Dahl III T, Spurkland A, Eriksen JA., Thorsby E, Gaudernack G. Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln→Leu61). Int. Immunol. 1992. 4: 1331.
    • (1992) Int. Immunol , vol.4 , pp. 1331
    • Gedde-Dahl III, T.1    Spurkland, A.2    Eriksen, J.A.3    Thorsby, E.4    Gaudernack, G.5
  • 8
    • 0028057702 scopus 로고
    • p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly→Asp)
    • Fossum B, Gedde-Dahl III T, Breivik J, Eriksen JA, Spurkland A, Thorsby E, Gaudernack G. p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly→Asp). Int J Cancer. 1994, 56: 40.
    • (1994) Int J Cancer , vol.56 , pp. 40
    • Fossum, B.1    Gedde-Dahl III, T.2    Breivik, J.3    Eriksen, J.A.4    Spurkland, A.5    Thorsby, E.6    Gaudernack, G.7
  • 11
    • 0028053024 scopus 로고
    • K-ras mutation in colorectal cancer: Relations to patient age, sex and tumour location
    • Breivik J, Meling GI, Spurkland A, Rognum TO, Gaudernack G. K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location. Br J Cancer. 1994. 69: 367.
    • (1994) Br J Cancer , vol.69 , pp. 367
    • Breivik, J.1    Meling, G.I.2    Spurkland, A.3    Rognum, T.O.4    Gaudernack, G.5
  • 13
    • 0026680448 scopus 로고
    • Clinical significance of ras oncogene activation in human lung cancer
    • Rodenhuis S, Slebos RJC. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res. 1992. 52: 2665.
    • (1992) Cancer Res , vol.52 , pp. 2665
    • Rodenhuis, S.1    Slebos, R.J.C.2
  • 14
    • 0029763279 scopus 로고    scopus 로고
    • Ki-ras point mutations and proliferation activity in biliary tract carcinomas
    • Ohashi K, Tsutsumi M, Nakajima Y, Nakano H, Konishi Y. Ki-ras point mutations and proliferation activity in biliary tract carcinomas. Br J Cancer. 1996. 74: 930.
    • (1996) Br J Cancer , vol.74 , pp. 930
    • Ohashi, K.1    Tsutsumi, M.2    Nakajima, Y.3    Nakano, H.4    Konishi, Y.5
  • 15
    • 0024438925 scopus 로고
    • Analysis of ras oncogenes in malignant melanoma and precursor lesions: Correlation of point mutations with differentiation phenotype
    • Albino AP, Nanus DM, Mentle IR, CordonGardo C, McNutt NS, Bressler J, Andreeff M. Analysis of ras oncogenes in malignant melanoma and precursor lesions: correlation of point mutations with differentiation phenotype. Oncogene 1989. 4: 1363.
    • (1989) Oncogene , vol.4 , pp. 1363
    • Albino, A.P.1    Nanus, D.M.2    Mentle, I.R.3    Cordongardo, C.4    McNutt, N.S.5    Bressler, J.6    Andreeff, M.7
  • 16
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in recognition and elimination of tumor cells
    • Greenberg PD. Adoptive T cell therapy of tumors: Mechanisms operative in recognition and elimination of tumor cells. Adv Immunol. 1991, 49: 281.
    • (1991) Adv Immunol , vol.49 , pp. 281
    • Greenberg, P.D.1
  • 17
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz RH, A cell culture model for T lymphocyte clonal anergy. Science 1990, 248: 1349.
    • (1990) Science , vol.248 , pp. 1349
    • Schwartz, R.H.1
  • 18
    • 0028237348 scopus 로고
    • CD28-B7 interactions in T-cell activation
    • Allison JP. CD28-B7 interactions in T-cell activation. Curr Op Immunol. 1994, 6: 414.
    • (1994) Curr Op Immunol , vol.6 , pp. 414
    • Allison, J.P.1
  • 19
    • 0026074766 scopus 로고
    • Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins
    • Jung S, Schluesener HJ. Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins. J. Exp. Med. 1991, 73: 273.
    • (1991) J. Exp. Med. , vol.73 , pp. 273
    • Jung, S.1    Schluesener, H.J.2
  • 20
    • 0027428762 scopus 로고
    • Overlapping epitopes encompassing a point mutation (12Gly→Arg) in p21 ras can be recognized by HLA-DR, -DP and -DQ restricted T cells
    • Possum B, Gedde-Dahl III T, Hansen T, Eriksen JA, Thorsby E, Gaudemack G. Overlapping epitopes encompassing a point mutation (12Gly→Arg) in p21 ras can be recognized by HLA-DR, -DP and -DQ restricted T cells. Eur J Immunol. 1993, 23: 2687.
    • (1993) Eur J Immunol , vol.23 , pp. 2687
    • Possum, B.1    Gedde-Dahl III, T.2    Hansen, T.3    Eriksen, J.A.4    Thorsby, E.5    Gaudemack, G.6
  • 24
    • 0028153777 scopus 로고
    • Growth inhibition of a colonic adenocarcinoma cell line (HT29) by T cells specific for mutant p21 ras
    • Gedde-Dahl III T, Nilsen E, Thorsby E, Gaudernack G. Growth inhibition of a colonic adenocarcinoma cell line (HT29) by T cells specific for mutant p21 ras. Cancer Immunol Immunother. 1994b, 38: 127.
    • (1994) Cancer Immunol Immunother , vol.38 , pp. 127
    • Gedde-Dahl III, T.1    Nilsen, E.2    Thorsby, E.3    Gaudernack, G.4
  • 25
    • 0028934910 scopus 로고
    • CD8+ T cells from a patient with colon carcinoma, specific for a mutant p21 ras derived peptide (13Gly→Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation
    • Possum B, Olsen AC, Thorsby E, Gaudernack, G. CD8+ T cells from a patient with colon carcinoma, specific for a mutant p21 ras derived peptide (13Gly→Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation. Cancer Immunol. Immunother. 1995, 40: 165.
    • (1995) Cancer Immunol. Immunother. , vol.40 , pp. 165
    • Possum, B.1    Olsen, A.C.2    Thorsby, E.3    Gaudernack, G.4
  • 26
    • 0028856743 scopus 로고
    • Vaccination with mutant ras peptides and induction of T cell responsiveness in pancreatic-carcinoma patients after mutant ras peptide vaccination
    • Gjertsen MK, Bakka A, Breivik J, Saeterdal I, Solheim BG, Sereide O, Thorsby E,Gaudemack G: Vaccination with mutant ras peptides and induction of T cell responsiveness in pancreatic-carcinoma patients after mutant ras peptide vaccination. Lancet 1995;346:1399-1400.
    • (1995) Lancet , vol.346 , pp. 1399-1400
    • Gjertsen, M.K.1    Bakka, A.2    Breivik, J.3    Saeterdal, I.4    Solheim, B.G.5    Sereide, O.6    Thorsby, E.7    Gaudemack, G.8
  • 29
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • Cella M, Engering A, Pinet V, Pieters J, Lanzavecchia A. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 1997;388(6644):782-787.
    • (1997) Nature , vol.388 , Issue.6644 , pp. 782-787
    • Cella, M.1    Engering, A.2    Pinet, V.3    Pieters, J.4    Lanzavecchia, A.5
  • 30
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinmann RM. The dendritic cell system and its role in immunogenicity. Ann Rev Immunol. 1991;9:271-296.
    • (1991) Ann Rev Immunol , vol.9 , pp. 271-296
    • Steinmann, R.M.1
  • 31
    • 0028137762 scopus 로고
    • T cell epitopes encompassing the mutational hot spot position 61 of p21 ras. Promiscuity in ras peptide binding to HLA
    • Gedde-Dahl III T, Spurkland A, Possum B, Wittinghofer A, Thorsby E, Gaudernack G. T cell epitopes encompassing the mutational hot spot position 61 of p21 ras. Promiscuity in ras peptide binding to HLA. Eur J Immunol. 1994a. 24: 410.
    • (1994) Eur J Immunol. , vol.24 , pp. 410
    • Gedde-Dahl III, T.1    Spurkland, A.2    Possum, B.3    Wittinghofer, A.4    Thorsby, E.5    Gaudernack, G.6
  • 33
    • 0029825827 scopus 로고    scopus 로고
    • Characterisation of immune responses in pancreatic carcinoma patients after mutant-p21-ras peptide vaccination
    • Gjertsen MK, Sæterdal I, Thorsby E, Gaudernack G. Characterisation of immune responses in pancreatic carcinoma patients after mutant-p21-ras peptide vaccination. Brit J Cancer. 1996;74:1828-1833.
    • (1996) Brit J Cancer , vol.74 , pp. 1828-1833
    • Gjertsen, M.K.1    Sæterdal, I.2    Thorsby, E.3    Gaudernack, G.4
  • 36
    • 0026733449 scopus 로고
    • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogenous in size
    • Chicz RM, Urban RG, Lane WS, Gorga JC, Stern LJ, Vignali DAA, Strominger JL. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogenous in size. Nature 1992. 358: 764.
    • (1992) Nature , vol.358 , pp. 764
    • Chicz, R.M.1    Urban, R.G.2    Lane, W.S.3    Gorga, J.C.4    Stern, L.J.5    Vignali, D.A.A.6    Strominger, J.L.7
  • 37
    • 0030749292 scopus 로고    scopus 로고
    • Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12-Val dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation
    • Gjertsen MK, Bjørheim J, Sæterdal I, Myklebust J, Gaudernack G. Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12-Val dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation. Int J Cancer 1997;72:784-790.
    • (1997) Int J Cancer , vol.72 , pp. 784-790
    • Gjertsen, M.K.1    Bjørheim, J.2    Sæterdal, I.3    Myklebust, J.4    Gaudernack, G.5
  • 38
    • 0026555250 scopus 로고
    • Overlapping epitopes that are recognized by CD8+ HLA class I-restricted and CD4+ class II-restricted cytotoxic T lymphocytes are contained within an influenza nucleoprotein peptide
    • Carreno BM, Turner RV, Biddison WE, Coligan JE. Overlapping epitopes that are recognized by CD8+ HLA class I-restricted and CD4+ class II-restricted cytotoxic T lymphocytes are contained within an influenza nucleoprotein peptide. J Immunol. 1992. 148: 894.
    • (1992) J Immunol , vol.148 , pp. 894
    • Carreno, B.M.1    Turner, R.V.2    Biddison, W.E.3    Coligan, J.E.4
  • 39
    • 0024410347 scopus 로고
    • Identical peptides recognized by MHC class I-and class II-restricted T cells
    • Perkins DL, Lai M-Z, Smith JA, Gefter ML. Identical peptides recognized by MHC class I-and class II-restricted T cells. J. Exp. Med. 1989. 170: 279.
    • (1989) J. Exp. Med. , vol.170 , pp. 279
    • Perkins, D.L.1    Lai, M.-Z.2    Smith, J.A.3    Gefter, M.L.4
  • 40
    • 0025022393 scopus 로고
    • An immuno-dominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type I induces CD4 class II-restricted help for itself
    • Takahashi H, Germain RN, Moss B, et al. An immuno-dominant class I-restricted cytotoxic T lymphocyte determinant of human immunodeficiency virus type I induces CD4 class II-restricted help for itself. J Exp Med. 1990. 171: 571.
    • (1990) J Exp Med , vol.171 , pp. 571
    • Takahashi, H.1    Germain, R.N.2    Moss, B.3
  • 41
    • 0028281585 scopus 로고
    • Interleukin 12: A key modulator of immune function
    • Wolf SF, Sieburth D, Sypek J. Interleukin 12: a key modulator of immune function. Stem Cells Dayt. 1994. 12 (2): 154.
    • (1994) Stem Cells Dayt , vol.12 , Issue.2 , pp. 154
    • Wolf, S.F.1    Sieburth, D.2    Sypek, J.3
  • 42
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against CMV in recipients of allogeneic bone marrow by adoptive transfer of T cell clones from the donor
    • Walter, E. A., Greenberg, P. D., Gilbert, M. J., Finch, R. J., Watanabe, K. S., Thomas, E. D. and Riddell, S. R. Reconstitution of cellular immunity against CMV in recipients of allogeneic bone marrow by adoptive transfer of T cell clones from the donor. N Engl J Med. 1995. 333: 1038.
    • (1995) N Engl J Med , vol.333 , pp. 1038
    • Walter, E.A.1    Greenberg, P.D.2    Gilbert, M.J.3    Finch, R.J.4    Watanabe, K.S.5    Thomas, E.D.6    Riddell, S.R.7
  • 44
    • 0030027269 scopus 로고    scopus 로고
    • Identification of overlapping epitopes in mutant ras oncogene peptides that activate CD4+ and CD8+ T cell responses
    • Abrams SI, Stanziale SF, Lunin SD, Zaremba S, Schlom J. Identification of overlapping epitopes in mutant ras oncogene peptides that activate CD4+ and CD8+ T cell responses. Eur J Immunol. 1996. 26: 435.
    • (1996) Eur J Immunol , vol.26 , pp. 435
    • Abrams, S.I.1    Stanziale, S.F.2    Lunin, S.D.3    Zaremba, S.4    Schlom, J.5
  • 45
    • 0029997742 scopus 로고
    • Generation of cytotoxic T-cell responses with synthetic melanoma associated peptides in vivo: Implications for tumor vaccines with melanoma-associated antigens
    • Jäger E, Bernhard H, Romero P, Ringhoffer M, Arand M, Karbach J, Ilsemann C, Hagedorn M, Knuth A, Generation of cytotoxic T-cell responses with synthetic melanoma associated peptides in vivo: Implications for tumor vaccines with melanoma-associated antigens. Int J Cancer. 1966. 66: 162.
    • (1966) Int J Cancer , vol.66 , pp. 162
    • Jäger, E.1    Bernhard, H.2    Romero, P.3    Ringhoffer, M.4    Arand, M.5    Karbach, J.6    Ilsemann, C.7    Hagedorn, M.8    Knuth, A.9
  • 47
    • 0029987485 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor: An effective adjuvant for protein and peptide-based vaccines
    • Disis ML, Bernhard H, Shiota FM et al. Granulocyte-macrophage colony-stimulating factor: An effective adjuvant for protein and peptide-based vaccines. Blood 1996. 88: 202.
    • (1996) Blood , vol.88 , pp. 202
    • Disis, M.L.1    Bernhard, H.2    Shiota, F.M.3
  • 48
    • 0030000146 scopus 로고    scopus 로고
    • Inverse relationship of melanocyte-differentiation antigen expression in melanoma: Evidence for immunoselection of antigen-loss variants in vivo
    • Jäger E, Ringhoffer M, Karbach J, Arand M, Oesch F, Knuth A. Inverse relationship of melanocyte-differentiation antigen expression in melanoma: Evidence for immunoselection of antigen-loss variants in vivo. Int J Cancer. 1996. 66: 470.
    • (1996) Int J Cancer , vol.66 , pp. 470
    • Jäger, E.1    Ringhoffer, M.2    Karbach, J.3    Arand, M.4    Oesch, F.5    Knuth, A.6
  • 49
    • 0029840729 scopus 로고    scopus 로고
    • Detection of ras gene mutations in perioperative peripheral blood with pancreatic adenocarcinoma
    • Nomoto S, Nakao A, Kasai Y, Harada A, Nonami T, Takagi H. Detection of ras gene mutations in perioperative peripheral blood with pancreatic adenocarcinoma. Jpn J Cancer Res 1996;87:793-797.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 793-797
    • Nomoto, S.1    Nakao, A.2    Kasai, Y.3    Harada, A.4    Nonami, T.5    Takagi, H.6


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