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Volumn 25, Issue 3, 1999, Pages 291-309

Hyperhomocysteinemia and thrombosis

Author keywords

Atherosclerosis; Homocysteine; Methionine; Thrombosis; Vitamins

Indexed keywords

AGE; ATHEROSCLEROSIS; CONFERENCE PAPER; DISEASE ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; HYPERHOMOCYSTEINEMIA; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; THROMBOSIS; VEIN OCCLUSION; VITAMIN BLOOD LEVEL;

EID: 0032783269     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-994932     Document Type: Conference Paper
Times cited : (53)

References (181)
  • 1
    • 0014545138 scopus 로고
    • Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
    • McCully K. Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis. Am J Pathol 1969;56:111-128
    • (1969) Am J Pathol , vol.56 , pp. 111-128
    • McCully, K.1
  • 3
    • 0017284939 scopus 로고
    • The pathogenesis of coronary artery disease. A possible role for methionine metabolism
    • Wilcken D, Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest 1976;57:1079-1082
    • (1976) J Clin Invest , vol.57 , pp. 1079-1082
    • Wilcken, D.1    Wilcken, B.2
  • 4
    • 0030694694 scopus 로고    scopus 로고
    • Association between plasma homocysteine and coronary artery disease in older persons
    • Aronow W, Ahn C. Association between plasma homocysteine and coronary artery disease in older persons. Am J Cardiol 1997;80:1216-1218
    • (1997) Am J Cardiol , vol.80 , pp. 1216-1218
    • Aronow, W.1    Ahn, C.2
  • 5
    • 0021998698 scopus 로고
    • Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease
    • Boers G, Smals A, Trijbels F, et al. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease. N Engl J Med 1985;313:709-715
    • (1985) N Engl J Med , vol.313 , pp. 709-715
    • Boers, G.1    Smals, A.2    Trijbels, F.3
  • 6
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease
    • Boushey C, Beresford S, Omenn G, Motulsky A. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA 1995;274:1049-1057
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.1    Beresford, S.2    Omenn, G.3    Motulsky, A.4
  • 7
    • 0025756673 scopus 로고
    • Hyperhomocysteinemia: An independent risk factor for vascular disease
    • Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia: An independent risk factor for vascular disease. N Engl J Med 1991;324:1149-1155
    • (1991) N Engl J Med , vol.324 , pp. 1149-1155
    • Clarke, R.1    Daly, L.2    Robinson, K.3
  • 8
    • 0030971062 scopus 로고    scopus 로고
    • Homocysteine and thrombotic disease
    • D'Angelo A, Selhub J. Homocysteine and thrombotic disease. Blood 1997;90:1-11
    • (1997) Blood , vol.90 , pp. 1-11
    • D'Angelo, A.1    Selhub, J.2
  • 10
    • 0029921114 scopus 로고    scopus 로고
    • Hyperhomocysteinemia as a risk factor for deep-vein thrombosis
    • den Heijer M, Koster T, Blom H, et al. Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med 1996;334:759-762
    • (1996) N Engl J Med , vol.334 , pp. 759-762
    • Den Heijer, M.1    Koster, T.2    Blom, H.3
  • 11
    • 0029876985 scopus 로고    scopus 로고
    • Inherited thrombophilia: Pathogenesis, clinical syndromes, and management
    • De Stefano V, Finazzi G, Mannucci P. Inherited thrombophilia: Pathogenesis, clinical syndromes, and management. Blood 1996;87:3531-3544
    • (1996) Blood , vol.87 , pp. 3531-3544
    • De Stefano, V.1    Finazzi, G.2    Mannucci, P.3
  • 13
    • 0028853921 scopus 로고
    • Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease
    • Fermo I, Vigano' D'Angelo V, Paroni R, et al. Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease. Ann Intern Med 1995;123:747-753
    • (1995) Ann Intern Med , vol.123 , pp. 747-753
    • Fermo, I.1    Vigano' D'Angelo, V.2    Paroni, R.3
  • 14
    • 0030937138 scopus 로고    scopus 로고
    • Mild hyperhomocysteinemia and hemostatic factors in patients with arterial vascular diseases
    • Freyburger G, Labrouche S, Sassoust G, et al. Mild hyperhomocysteinemia and hemostatic factors in patients with arterial vascular diseases. Thromb Haemost 1997;77:466-471
    • (1997) Thromb Haemost , vol.77 , pp. 466-471
    • Freyburger, G.1    Labrouche, S.2    Sassoust, G.3
  • 15
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom H, Milos R, et al. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nature Genet 1995;10:111-113
    • (1995) Nature Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.2    Milos, R.3
  • 16
    • 0028834216 scopus 로고
    • Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients
    • Glueck C, Shaw P, Lang J, et al. Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients. Am J Cardiol 1995;75:132-136
    • (1995) Am J Cardiol , vol.75 , pp. 132-136
    • Glueck, C.1    Shaw, P.2    Lang, J.3
  • 17
    • 1842331509 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for vascular disease
    • Graham I, Daly L, Refsum H, et al. Plasma homocysteine as a risk factor for vascular disease. JAMA 1997;277:1775-1781
    • (1997) JAMA , vol.277 , pp. 1775-1781
    • Graham, I.1    Daly, L.2    Refsum, H.3
  • 18
    • 0030460152 scopus 로고    scopus 로고
    • Hyperhomocysteinemia: An emerging and important risk factor for thromboembolic and cardiovascular disease
    • Guba S, Fink L, Fonseca V. Hyperhomocysteinemia: An emerging and important risk factor for thromboembolic and cardiovascular disease. Am J Clin Pathol 1996;105:709-722
    • (1996) Am J Clin Pathol , vol.105 , pp. 709-722
    • Guba, S.1    Fink, L.2    Fonseca, V.3
  • 19
    • 0031967236 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and premature vascular occlusive disease
    • Guba S, Fink L, Fonseca V. Hyperhomocysteinemia and premature vascular occlusive disease. Am J Med Sci 1998;315: 279-285
    • (1998) Am J Med Sci , vol.315 , pp. 279-285
    • Guba, S.1    Fink, L.2    Fonseca, V.3
  • 20
    • 0029088620 scopus 로고
    • Higher plasma homocyst(e)ine and increased susceptibility to adverse effects of low folate in early familial coronary artery disease
    • Hopkins P, Wu L, Wu J, et al. Higher plasma homocyst(e)ine and increased susceptibility to adverse effects of low folate in early familial coronary artery disease. Arterioscler Thromb Vasc Biol 1995;15:1314-1320
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1314-1320
    • Hopkins, P.1    Wu, L.2    Wu, J.3
  • 21
    • 0031964467 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus. A population based study
    • Hoogeveen E, Kostense P, Beks P, et al. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus. A population based study. Arterioscler Thromb Vasc Biol 1998;18:133-138
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 133-138
    • Hoogeveen, E.1    Kostense, P.2    Beks, P.3
  • 22
    • 0027421353 scopus 로고
    • Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease
    • Kang S, Passen E, Ruggie N, Wong P, Sora H. Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation 1993;88:1463-1469
    • (1993) Circulation , vol.88 , pp. 1463-1469
    • Kang, S.1    Passen, E.2    Ruggie, N.3    Wong, P.4    Sora, H.5
  • 23
    • 0029655724 scopus 로고    scopus 로고
    • Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
    • Kluijtmans L, van den Heuvel L, Boers G, et al. Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 1996;58:35-41
    • (1996) Am J Hum Genet , vol.58 , pp. 35-41
    • Kluijtmans, L.1    Van den Heuvel, L.2    Boers, G.3
  • 24
    • 0030912329 scopus 로고    scopus 로고
    • Correlation between plasma homocyst(e)ine and aortic atherosclerosis
    • Konechy N, Malinow M, Tunick P, et al. Correlation between plasma homocyst(e)ine and aortic atherosclerosis. Am Heart J 1997;133:534-540
    • (1997) Am Heart J , vol.133 , pp. 534-540
    • Konechy, N.1    Malinow, M.2    Tunick, P.3
  • 25
    • 0031426012 scopus 로고    scopus 로고
    • High plasma homocysteine: A risk factor for arterial and venous thrombosis in patients with normal coagulation profiles
    • Kottke-Marchant K, Green R, Jacobsen D, et al. High plasma homocysteine: A risk factor for arterial and venous thrombosis in patients with normal coagulation profiles. Clin Appl Thromb/Hemost 1997;3:239-244
    • (1997) Clin Appl Thromb/Hemost , vol.3 , pp. 239-244
    • Kottke-Marchant, K.1    Green, R.2    Jacobsen, D.3
  • 26
    • 0028907918 scopus 로고
    • Plasma homocysteine in the acute and convalescent phases after stroke
    • Lindgren A, Brattstrom L, Norrving B, et al. Plasma homocysteine in the acute and convalescent phases after stroke. Stroke 1995;26:795-800
    • (1995) Stroke , vol.26 , pp. 795-800
    • Lindgren, A.1    Brattstrom, L.2    Norrving, B.3
  • 27
    • 0025155188 scopus 로고
    • Homosyt(e)inemia in daily practice: Levels in coronary artery disease
    • Malinow M, Sexton G, Averbuch M, et al. Homosyt(e)inemia in daily practice: Levels in coronary artery disease. Coronary Artery Disease 1990;1:215-220
    • (1990) Coronary Artery Disease , vol.1 , pp. 215-220
    • Malinow, M.1    Sexton, G.2    Averbuch, M.3
  • 28
    • 0027523674 scopus 로고
    • Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults
    • Malinow M, Nieto F, Szklo M, Chambless L, Bond G. Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. Circulation 1993;87:1107-1113
    • (1993) Circulation , vol.87 , pp. 1107-1113
    • Malinow, M.1    Nieto, F.2    Szklo, M.3    Chambless, L.4    Bond, G.5
  • 29
    • 0024391453 scopus 로고
    • Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease
    • Malinow M, Kang S, Taylor L, et al. Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease. Circulation 1989;79:1180-1188
    • (1989) Circulation , vol.79 , pp. 1180-1188
    • Malinow, M.1    Kang, S.2    Taylor, L.3
  • 30
    • 0028893446 scopus 로고
    • Plasma homocyst(e)ine and arterial occlusive diseases: A mini-review
    • Malinow M. Plasma homocyst(e)ine and arterial occlusive diseases: A mini-review. Clin Chem 1995;41:173-176
    • (1995) Clin Chem , vol.41 , pp. 173-176
    • Malinow, M.1
  • 31
    • 0029918751 scopus 로고    scopus 로고
    • Plasma homocyst(e)ine: A risk factor for arterial oclusive diseases
    • Malinow M. Plasma homocyst(e)ine: A risk factor for arterial oclusive diseases. J Nutr 1996;126:1238S-1243S
    • (1996) J Nutr , vol.126
    • Malinow, M.1
  • 32
    • 0029933176 scopus 로고    scopus 로고
    • Coexistence of hereditary homocystinuria and factor V Leiden - Effect on thrombosis
    • Mandel H, Brenner B, Berant M, et al. Coexistence of hereditary homocystinuria and factor V Leiden - Effect on thrombosis. N Engl J Med 1996;334:763-768
    • (1996) N Engl J Med , vol.334 , pp. 763-768
    • Mandel, H.1    Brenner, B.2    Berant, M.3
  • 33
    • 0029655527 scopus 로고    scopus 로고
    • Nutritional ecogenetics: Homocysteine-related arteriosclerotic vascular disease, neural tube defects, and folic acid
    • Motulsky A. Nutritional ecogenetics: Homocysteine-related arteriosclerotic vascular disease, neural tube defects, and folic acid. Am J Hum Genet 1996;58:17-20
    • (1996) Am J Hum Genet , vol.58 , pp. 17-20
    • Motulsky, A.1
  • 34
    • 0031543485 scopus 로고    scopus 로고
    • Homocysteinemia as a risk factor for atherosclerosis: A review
    • Nehler M, Taylor LJ, Porter J. Homocysteinemia as a risk factor for atherosclerosis: A review. Cardiovasc Surg 1997;5:559-567
    • (1997) Cardiovasc Surg , vol.5 , pp. 559-567
    • Nehler, M.1    Taylor, L.J.2    Porter, J.3
  • 35
    • 0028788020 scopus 로고
    • Total plasma homocysteine and cardiovascular risk profile: The Hordaland homocysteine study
    • Nygard O, Vollset S, Refsum H, et al. Total plasma homocysteine and cardiovascular risk profile: The Hordaland homocysteine study. JAMA 1995;274:1526-1533
    • (1995) JAMA , vol.274 , pp. 1526-1533
    • Nygard, O.1    Vollset, S.2    Refsum, H.3
  • 36
    • 1842370239 scopus 로고    scopus 로고
    • Plasma homocysteine levels and mortality in patients with coronary artery disease
    • Nygard O, Nordrehaug J, Refsum H, et al. Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 1997;1337:230-236
    • (1997) N Engl J Med , vol.1337 , pp. 230-236
    • Nygard, O.1    Nordrehaug, J.2    Refsum, H.3
  • 38
    • 0030953866 scopus 로고    scopus 로고
    • Interrelation of hyperhomocyst(e)inemia, Factor V Leiden, and risk of future venous thromboembolism
    • Ridker P, Hennekens C, Selhub J, et al. Interrelation of hyperhomocyst(e)inemia. Factor V Leiden, and risk of future venous thromboembolism. Circulation 1997;95:1777-1782
    • (1997) Circulation , vol.95 , pp. 1777-1782
    • Ridker, P.1    Hennekens, C.2    Selhub, J.3
  • 39
    • 0026684554 scopus 로고
    • A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians
    • Stampfer M, Malinow M, Willett W, et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA 1992;268:877-881
    • (1992) JAMA , vol.268 , pp. 877-881
    • Stampfer, M.1    Malinow, M.2    Willett, W.3
  • 40
    • 0028966321 scopus 로고
    • Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis
    • Selhub J, Jacques P, Bostom A, et al. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995;332:286-291
    • (1995) N Engl J Med , vol.332 , pp. 286-291
    • Selhub, J.1    Jacques, P.2    Bostom, A.3
  • 41
    • 0030945254 scopus 로고    scopus 로고
    • Elevated high-density lipoprotein cholesterol, not protective in the presence of homocysteinemia
    • Superko H. Elevated high-density lipoprotein cholesterol, not protective in the presence of homocysteinemia. Am J Cardiol 1997;79:705-706
    • (1997) Am J Cardiol , vol.79 , pp. 705-706
    • Superko, H.1
  • 43
    • 0030994488 scopus 로고    scopus 로고
    • Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis
    • Verhoef P, Kok F, Kruyssen D, et al. Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis. Arteriosclerosis Thromb Vasc Biol 1997;17:989-995
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 989-995
    • Verhoef, P.1    Kok, F.2    Kruyssen, D.3
  • 44
    • 0030893673 scopus 로고    scopus 로고
    • Plasma total homocysteine and risk of angina pectoris with subsequent coronary artery bypass surgery
    • Verhoef P, Hennekens C, Allen R, et al. Plasma total homocysteine and risk of angina pectoris with subsequent coronary artery bypass surgery. Am J Cardiol 1997;79:799-801
    • (1997) Am J Cardiol , vol.79 , pp. 799-801
    • Verhoef, P.1    Hennekens, C.2    Allen, R.3
  • 45
    • 0028132586 scopus 로고
    • A prospective study of plasma homocyst(e)ine and risk of ischemic stroke
    • Verhoef P, Hennekens C, Malinow M, et al. A prospective study of plasma homocyst(e)ine and risk of ischemic stroke. Stroke 1994;25:1924-1930
    • (1994) Stroke , vol.25 , pp. 1924-1930
    • Verhoef, P.1    Hennekens, C.2    Malinow, M.3
  • 46
    • 0031801972 scopus 로고    scopus 로고
    • Association between elevated plasma total homocysteine and increased common carotid artery wall thickness
    • Voutilainen S, Alfthan G, Nyyssonen K, Salonen R, Salonen J. Association between elevated plasma total homocysteine and increased common carotid artery wall thickness. Ann Med 1998;30:300-306
    • (1998) Ann Med , vol.30 , pp. 300-306
    • Voutilainen, S.1    Alfthan, G.2    Nyyssonen, K.3    Salonen, R.4    Salonen, J.5
  • 47
    • 0032571596 scopus 로고    scopus 로고
    • Homocysteine and ischemic heart disease
    • Wald N, Watt H, Law M, et al. Homocysteine and ischemic heart disease. Arch Intern Med 1998;158:862-867
    • (1998) Arch Intern Med , vol.158 , pp. 862-867
    • Wald, N.1    Watt, H.2    Law, M.3
  • 48
    • 0028210769 scopus 로고
    • Plasma homocyst(e)ine as a risk factor for early familial coronary artery disease
    • Wu L, Wu J, Hunt S, et al. Plasma homocyst(e)ine as a risk factor for early familial coronary artery disease. Clin Chem 1994;40:552-561
    • (1994) Clin Chem , vol.40 , pp. 552-561
    • Wu, L.1    Wu, J.2    Hunt, S.3
  • 49
    • 0029029934 scopus 로고
    • Plasma homocyst(e)ine or homocysteine?
    • Mudd S, Levy H. Plasma homocyst(e)ine or homocysteine? N Engl J Med 1995;333:325
    • (1995) N Engl J Med , vol.333 , pp. 325
    • Mudd, S.1    Levy, H.2
  • 50
    • 0027293835 scopus 로고
    • Total homocysteine in plasma or serum: Methods in clinical applications
    • Ueland P, Refsum H, Stabler S, et al. Total homocysteine in plasma or serum: Methods in clinical applications. Clin Chem 1993;39:1764-1779
    • (1993) Clin Chem , vol.39 , pp. 1764-1779
    • Ueland, P.1    Refsum, H.2    Stabler, S.3
  • 51
    • 0023628783 scopus 로고
    • Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
    • Araki A, Sako Y. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 1987;422:43-52
    • (1987) J Chromatogr , vol.422 , pp. 43-52
    • Araki, A.1    Sako, Y.2
  • 52
    • 85066230103 scopus 로고
    • Rapid high performance liquid chromatographic assay for total homocysteine levels in human serum
    • Ubbink J, Vermaak W, Bissbort S. Rapid high performance liquid chromatographic assay for total homocysteine levels in human serum. Eur J Clin Chem Clin Biol Chem 1991;29:549-554
    • (1991) Eur J Clin Chem Clin Biol Chem , vol.29 , pp. 549-554
    • Ubbink, J.1    Vermaak, W.2    Bissbort, S.3
  • 53
    • 0027462812 scopus 로고
    • Homocysteine and other thiols in plasma and urine: Automated determination in sample stability
    • Fiskerstrand T, Refsum H, Kvalheim G, Eulan P. Homocysteine and other thiols in plasma and urine: Automated determination in sample stability. Clin Chem 1993;39:263-271
    • (1993) Clin Chem , vol.39 , pp. 263-271
    • Fiskerstrand, T.1    Refsum, H.2    Kvalheim, G.3    Eulan, P.4
  • 54
    • 0028960103 scopus 로고
    • Determination of homocysteine by HPLC with pulsed integrated amperometry
    • Evrovski J, Kalaghan M, Cole D. Determination of homocysteine by HPLC with pulsed integrated amperometry. Clin Chem 1995;41:757-758
    • (1995) Clin Chem , vol.41 , pp. 757-758
    • Evrovski, J.1    Kalaghan, M.2    Cole, D.3
  • 55
    • 0027248275 scopus 로고
    • Homocysteine and other thiols determined in plasma by HPLC and thiol-specific postcolumn derivatization
    • Anderson A, Isaksson A, Brattstrom L, Hultberg B. Homocysteine and other thiols determined in plasma by HPLC and thiol-specific postcolumn derivatization. Clin Chem 1993;39:1590-1597
    • (1993) Clin Chem , vol.39 , pp. 1590-1597
    • Anderson, A.1    Isaksson, A.2    Brattstrom, L.3    Hultberg, B.4
  • 56
    • 0029035643 scopus 로고
    • Rapid, fully automated measurement of plasma homocyst(e)ine with the Abbott Imx Analyser
    • Shipchandler M, Moore E. Rapid, fully automated measurement of plasma homocyst(e)ine with the Abbott Imx Analyser. Clin Chem 1995;41:991-994
    • (1995) Clin Chem , vol.41 , pp. 991-994
    • Shipchandler, M.1    Moore, E.2
  • 57
    • 0032126003 scopus 로고    scopus 로고
    • Methionine loading test is necessary for detection of hyperhomocysteinemia
    • van der Griend R, Haas F, Duran M, et al. Methionine loading test is necessary for detection of hyperhomocysteinemia. J Lab Clin Med 1998;132:67-72
    • (1998) J Lab Clin Med , vol.132 , pp. 67-72
    • Van der Griend, R.1    Haas, F.2    Duran, M.3
  • 58
    • 85038170543 scopus 로고    scopus 로고
    • Comparison between the 2-hour and the 4-hour methionine loading test for the identification of subjects with methionine intolerance
    • Lombardi R, Cattaneo M, Agati B, et al. Comparison between the 2-hour and the 4-hour methionine loading test for the identification of subjects with methionine intolerance. Thromb Res 1998;91(Suppl 1):S16-S17
    • (1998) Thromb Res , vol.91 , Issue.SUPPL. 1
    • Lombardi, R.1    Cattaneo, M.2    Agati, B.3
  • 59
    • 0029915563 scopus 로고    scopus 로고
    • Hyperhomocysteinemia following a methionine load in patients with non-insulin-dependent diabetes mellitus and macrovascular disease
    • Munshi M, Stone A, Fink L, Fonseca V. Hyperhomocysteinemia following a methionine load in patients with non-insulin-dependent diabetes mellitus and macrovascular disease. Metabolism 1996;45:133-135
    • (1996) Metabolism , vol.45 , pp. 133-135
    • Munshi, M.1    Stone, A.2    Fink, L.3    Fonseca, V.4
  • 60
    • 0030015522 scopus 로고    scopus 로고
    • Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia
    • Lentz S, Sobey C, Piegors D, et al. Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia. J Clin Invest 1996;98:24-29
    • (1996) J Clin Invest , vol.98 , pp. 24-29
    • Lentz, S.1    Sobey, C.2    Piegors, D.3
  • 61
    • 0029928653 scopus 로고    scopus 로고
    • Pro-thrombotic effects of a folic acid deficient diet in rat platelets and macrophages related to elevated homocysteine and decreased n-3 polyunsaturated fatty acids
    • Durand P, Prost M, Blache D. Pro-thrombotic effects of a folic acid deficient diet in rat platelets and macrophages related to elevated homocysteine and decreased n-3 polyunsaturated fatty acids. Atherosclerosis 1996;121:231-243
    • (1996) Atherosclerosis , vol.121 , pp. 231-243
    • Durand, P.1    Prost, M.2    Blache, D.3
  • 62
    • 0030728675 scopus 로고    scopus 로고
    • Acute methionine load-induced hyperhomocysteinemia enhances platelet aggregation, thromboxane biosynthesis, and macrophage-derived tissue factor activity in rats
    • Durand P, Lussier-Cacan S, Blache D. Acute methionine load-induced hyperhomocysteinemia enhances platelet aggregation, thromboxane biosynthesis, and macrophage-derived tissue factor activity in rats. FASEB Lett 1997;11:1157-1168
    • (1997) FASEB Lett , vol.11 , pp. 1157-1168
    • Durand, P.1    Lussier-Cacan, S.2    Blache, D.3
  • 64
    • 0031773609 scopus 로고    scopus 로고
    • Hyperhomocysteinemia increases intimal hyperplasia in a rat carotid endarterectomy model
    • Southern F, Cruz N, Fink L, et al. Hyperhomocysteinemia increases intimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg 1998;28:909-918
    • (1998) J Vasc Surg , vol.28 , pp. 909-918
    • Southern, F.1    Cruz, N.2    Fink, L.3
  • 65
    • 0000167774 scopus 로고
    • Disorders of transsulfuration
    • Scriver C, Beaudet A, Sly W, et al, eds. New York: McGraw-Hill
    • Mudd S, Levy H, Skovby F. Disorders of transsulfuration. In: Scriver C, Beaudet A, Sly W, et al, eds: The Metabolic Basis of Inherited Disease (Ed 7th). New York: McGraw-Hill, 1995;1279-1327
    • (1995) The Metabolic Basis of Inherited Disease (Ed 7th) , pp. 1279-1327
    • Mudd, S.1    Levy, H.2    Skovby, F.3
  • 66
    • 1842378618 scopus 로고    scopus 로고
    • Homocysteine, oxidative stress, and vascular disease
    • Welch G, Upchurch G, Loscalzo J. Homocysteine, oxidative stress, and vascular disease. Hosp Pract 1997;32:81-92
    • (1997) Hosp Pract , vol.32 , pp. 81-92
    • Welch, G.1    Upchurch, G.2    Loscalzo, J.3
  • 67
    • 0016837233 scopus 로고
    • Activation of cystathionine synthase by adenosylmethionine and adenosylethionine
    • Finkelstein J, Lyle W, Martin J, Pick A. Activation of cystathionine synthase by adenosylmethionine and adenosylethionine. Biochem Biophys Res Commun 1975;66:81-87
    • (1975) Biochem Biophys Res Commun , vol.66 , pp. 81-87
    • Finkelstein, J.1    Lyle, W.2    Martin, J.3    Pick, A.4
  • 68
    • 0023664009 scopus 로고
    • Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine
    • Jencks D, Matthews R. Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. J Biol Chem 1987;262:2485-2493
    • (1987) J Biol Chem , vol.262 , pp. 2485-2493
    • Jencks, D.1    Matthews, R.2
  • 69
    • 0025873535 scopus 로고
    • Homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency revealed by stroke in adult siblings
    • Visy J, Le Coz P, Chadefaux B, et al. Homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency revealed by stroke in adult siblings. Neurology 1991;41:1313-1315
    • (1991) Neurology , vol.41 , pp. 1313-1315
    • Visy, J.1    Le Coz, P.2    Chadefaux, B.3
  • 70
    • 0001640331 scopus 로고
    • Limited capacity for homocysteine catabolism in vascular cells and tissues: A pathophysiologic mechanism for arterial damage in hyperhomocysteinemia?
    • Jacobsen D, Savon S, Stewart R, et al. Limited capacity for homocysteine catabolism in vascular cells and tissues: A patho-physiologic mechanism for arterial damage in hyperhomocysteinemia? (Abstract). Circulation 1995;92:I-228
    • (1995) Circulation , vol.92
    • Jacobsen, D.1    Savon, S.2    Stewart, R.3
  • 71
    • 0027514869 scopus 로고
    • Cobalamin absorption and serum homocysteine and methylmalonic acid in elderly subjects with low serum cohalamin
    • Joosten E, Pelemans W, Devos P, et al. Cobalamin absorption and serum homocysteine and methylmalonic acid in elderly subjects with low serum cohalamin. Eur J Hematol 1993;51:25-30
    • (1993) Eur J Hematol , vol.51 , pp. 25-30
    • Joosten, E.1    Pelemans, W.2    Devos, P.3
  • 72
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J, Jacques P, Wilson P, Rush D, Rosenberg I. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993;270:2693-2698
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.2    Wilson, P.3    Rush, D.4    Rosenberg, I.5
  • 74
    • 0028143396 scopus 로고
    • Hormone replacement therapy may reduce high serum homocysteine in postmenopausal women
    • van der Mooren M, Wouters M, Blom H, et al. Hormone replacement therapy may reduce high serum homocysteine in postmenopausal women. Eur J Clin Invest 1994;24:733-736
    • (1994) Eur J Clin Invest , vol.24 , pp. 733-736
    • Van der Mooren, M.1    Wouters, M.2    Blom, H.3
  • 75
    • 0028821450 scopus 로고
    • Plasma levels of the atherogenic amino acid homocysteine in postmenopausal women with breast cancer treated with tamoxifen
    • Anker G, Lonning P, Ueland P, Refsum H, Lien E. Plasma levels of the atherogenic amino acid homocysteine in postmenopausal women with breast cancer treated with tamoxifen. Cancer 1995;60:365-368
    • (1995) Cancer , vol.60 , pp. 365-368
    • Anker, G.1    Lonning, P.2    Ueland, P.3    Refsum, H.4    Lien, E.5
  • 76
    • 0031747920 scopus 로고    scopus 로고
    • Tamoxifen reduces plasma homocysteine levels in healthy women
    • Cattaneo M, Baglietto L, Zighetti M, et al. Tamoxifen reduces plasma homocysteine levels in healthy women. Br J Cancer 1998;77:2264-2266
    • (1998) Br J Cancer , vol.77 , pp. 2264-2266
    • Cattaneo, M.1    Baglietto, L.2    Zighetti, M.3
  • 77
    • 0031862071 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and atherosclerotic vascular disease
    • Stein J, McBride P. Hyperhomocysteinemia and atherosclerotic vascular disease. Arch Intern Med 1998;158:1301-1306
    • (1998) Arch Intern Med , vol.158 , pp. 1301-1306
    • Stein, J.1    McBride, P.2
  • 78
    • 0031934299 scopus 로고    scopus 로고
    • Plasma total homocysteine levels in hyperthyroid and hypothyroid patients
    • Nedrebo B, Ericsson U-B, Nygard O, et al. Plasma total homocysteine levels in hyperthyroid and hypothyroid patients. Metabolism 1998;47:89-93
    • (1998) Metabolism , vol.47 , pp. 89-93
    • Nedrebo, B.1    Ericsson, U.-B.2    Nygard, O.3
  • 80
    • 0030060126 scopus 로고    scopus 로고
    • High dose-B-vitamin treatment of hyperhomocysteinemia in dialysis patients
    • Bostom A, Shemin D, Lapane K, et al. High dose-B-vitamin treatment of hyperhomocysteinemia in dialysis patients. Kidney Int 1996;49:147-152
    • (1996) Kidney Int , vol.49 , pp. 147-152
    • Bostom, A.1    Shemin, D.2    Lapane, K.3
  • 81
    • 0033304841 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and the endocrine system: Implications for atherosclerosis and thrombosis
    • in press
    • Fonseca V, Guba S, Fink L. Hyperhomocysteinemia and the endocrine system: Implications for atherosclerosis and thrombosis. Endocrine Rev in press, 1999
    • (1999) Endocrine Rev
    • Fonseca, V.1    Guba, S.2    Fink, L.3
  • 82
    • 0030775293 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM
    • Hoffman M, Kohl B, Zumbach M, et al. Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM. Diabetes Care 1997;20:1880-1886
    • (1997) Diabetes Care , vol.20 , pp. 1880-1886
    • Hoffman, M.1    Kohl, B.2    Zumbach, M.3
  • 83
    • 0031764553 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM
    • Hoffman M, Kohl B, Zumbach M, et al. Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM. Diabetes Care 1998;21:841-848
    • (1998) Diabetes Care , vol.21 , pp. 841-848
    • Hoffman, M.1    Kohl, B.2    Zumbach, M.3
  • 84
    • 0031470742 scopus 로고    scopus 로고
    • Excess prevalence of fasting and postmethionine-loading hyperhomocysteinemia in stable renal transplant patients
    • Bostom A, Gohh R, Tsai M, et al. Excess prevalence of fasting and postmethionine-loading hyperhomocysteinemia in stable renal transplant patients. Arteriosclerosis Thromb Vasc Biol 1997;17:1894-1900
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 1894-1900
    • Bostom, A.1    Gohh, R.2    Tsai, M.3
  • 85
    • 0030762686 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in end-stage renal disease: Prevalence, etiology, and potential relationship to arteriosclerotic outcomes
    • Bostom A, Lathrop L. Hyperhomocysteinemia in end-stage renal disease: Prevalence, etiology, and potential relationship to arteriosclerotic outcomes. Kidney Int 1997;52:10-20
    • (1997) Kidney Int , vol.52 , pp. 10-20
    • Bostom, A.1    Lathrop, L.2
  • 86
    • 0030811925 scopus 로고    scopus 로고
    • Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR)
    • Rozen R. Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR). Thromb Haemost 1997;78:523-526
    • (1997) Thromb Haemost , vol.78 , pp. 523-526
    • Rozen, R.1
  • 87
    • 0028918123 scopus 로고
    • Can lowering homocysteine levels reduce cardiovascular risk?
    • Stampfer M, Malinow M. Can lowering homocysteine levels reduce cardiovascular risk? N Engl J Med 1995;332:328-329
    • (1995) N Engl J Med , vol.332 , pp. 328-329
    • Stampfer, M.1    Malinow, M.2
  • 88
    • 0030804226 scopus 로고    scopus 로고
    • Sequence analysis of the coding region of human methionine synthase: Relevance to hyperhomocysteinaemia in neural tube defects and vascular disease
    • van der Put N, van der Molen E, Kluijtmans L, et al. Sequence analysis of the coding region of human methionine synthase: Relevance to hyperhomocysteinaemia in neural tube defects and vascular disease. Q J Med 1997;90:511-517
    • (1997) Q J Med , vol.90 , pp. 511-517
    • Van der Put, N.1    Van der Molen, E.2    Kluijtmans, L.3
  • 89
    • 0000526332 scopus 로고
    • Inherited disorders of cobalamin transport and metabolism
    • Scriver C, Beaudet A, Sly W, et al, eds. New York: McGraw-Hill, Inc
    • Fenton W, Rosenberg L. Inherited disorders of cobalamin transport and metabolism. In: Scriver C, Beaudet A, Sly W, et al, eds: The Metabolic Basis of Inherited Disease (Ed. 7th). New York: McGraw-Hill, Inc, 1995:3129-3149
    • (1995) The Metabolic Basis of Inherited Disease (Ed. 7th) , pp. 3129-3149
    • Fenton, W.1    Rosenberg, L.2
  • 90
    • 0027444787 scopus 로고
    • Human cystathionine β-synthase cDNA: Sequence, alternate splicing and expression in cultured cells
    • Kraus J, Le K, Swaroop M, et al. Human cystathionine β-synthase cDNA: Sequence, alternate splicing and expression in cultured cells. Hum Mol Genet 1993;2:1633-1638
    • (1993) Hum Mol Genet , vol.2 , pp. 1633-1638
    • Kraus, J.1    Le, K.2    Swaroop, M.3
  • 91
    • 0029078199 scopus 로고
    • Two novel missense mutations in the cystathionine β-synthase gene in homocystinuric patients
    • Kluijtmans L, Blom H, Boers G, et al. Two novel missense mutations in the cystathionine β-synthase gene in homocystinuric patients. Hum Genet 1995;96:249-250
    • (1995) Hum Genet , vol.96 , pp. 249-250
    • Kluijtmans, L.1    Blom, H.2    Boers, G.3
  • 92
    • 0028867566 scopus 로고
    • Amplification refractory mutation system to identify mutations in cystathionine β-synthase deficiency
    • Tsai M, Hansom N, Schwichtenberg K, Garg U. Amplification refractory mutation system to identify mutations in cystathionine β-synthase deficiency. Clin Chem 1995;41:1775-1777
    • (1995) Clin Chem , vol.41 , pp. 1775-1777
    • Tsai, M.1    Hansom, N.2    Schwichtenberg, K.3    Garg, U.4
  • 93
    • 0031243929 scopus 로고    scopus 로고
    • Different distribution of the double mutant "T833C/68 bp insertion" in cystathionine β-synthase gene in northern and southern Italian populations
    • Abst
    • Giusti B, Comeglio P, Attanasio M, et al. Different distribution of the double mutant "T833C/68 bp insertion" in cystathionine β-synthase gene in northern and southern Italian populations. Thromb Haemost 1997;78:1293 (Abst)
    • (1997) Thromb Haemost , vol.78 , pp. 1293
    • Giusti, B.1    Comeglio, P.2    Attanasio, M.3
  • 94
    • 0022476636 scopus 로고
    • Cloning and screening with nanogram amounts of immunopurified messenger RNAs, cDNA cloning and chromosomal mapping of cystathionine β-synthase and the β-subunit of propionyl CoA carboxylase
    • Kraus J, Williamson C, Firgaira F, et al. Cloning and screening with nanogram amounts of immunopurified messenger RNAs, cDNA cloning and chromosomal mapping of cystathionine β-synthase and the β-subunit of propionyl CoA carboxylase. Proc Natl Acad Sci USA 1986;83:2047-2051
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2047-2051
    • Kraus, J.1    Williamson, C.2    Firgaira, F.3
  • 95
    • 0023939665 scopus 로고
    • The gene for cystathionine β-synthase (CBS) maps to the subtelomeric region of human chromosome 21q to proximal mouse chromosome 17
    • Munke M, Kraus J, Ohura T, Francke U. The gene for cystathionine β-synthase (CBS) maps to the subtelomeric region of human chromosome 21q to proximal mouse chromosome 17. Am J Hum Genet 1988;42:550-559
    • (1988) Am J Hum Genet , vol.42 , pp. 550-559
    • Munke, M.1    Kraus, J.2    Ohura, T.3    Francke, U.4
  • 96
    • 0025361139 scopus 로고
    • Detection of heterozygotes for recessive alleles. Homocyst(e)inemia: Paradigm of pitfalls in phenotypes
    • McGill J, Mettler G, Rosenblatt D, Scriver C. Detection of heterozygotes for recessive alleles. Homocyst(e)inemia: Paradigm of pitfalls in phenotypes. Am J Med Genet 1990;36:45-52
    • (1990) Am J Med Genet , vol.36 , pp. 45-52
    • McGill, J.1    Mettler, G.2    Rosenblatt, D.3    Scriver, C.4
  • 97
    • 0031907640 scopus 로고    scopus 로고
    • Cystathionine β-synthase deficiency: Detection of heterozygotes by the ratios of homocysteine to cysteine and folate
    • Boddie A, Steen M, Sullivan K, et al. Cystathionine β-synthase deficiency: Detection of heterozygotes by the ratios of homocysteine to cysteine and folate. Metabolism 1998;47:207-211
    • (1998) Metabolism , vol.47 , pp. 207-211
    • Boddie, A.1    Steen, M.2    Sullivan, K.3
  • 98
    • 0029903031 scopus 로고    scopus 로고
    • Molecular and biochemical approaches in the identification of heterozygotes for homocystinuria
    • Tsai M, Garg U, Key N, et al. Molecular and biochemical approaches in the identification of heterozygotes for homocystinuria. Atherosclerosis 1996;122:69-77
    • (1996) Atherosclerosis , vol.122 , pp. 69-77
    • Tsai, M.1    Garg, U.2    Key, N.3
  • 99
    • 0030057995 scopus 로고    scopus 로고
    • Defective cystathionine β-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient
    • Kluijtmans L, Boers G, Stevens E, et al. Defective cystathionine β-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient. J Clin Invest 1996;98:285-289
    • (1996) J Clin Invest , vol.98 , pp. 285-289
    • Kluijtmans, L.1    Boers, G.2    Stevens, E.3
  • 100
    • 0030270624 scopus 로고    scopus 로고
    • Simultaneous detection and screening of T833C and G919A mutations of the cystathionine β-synthase gene by single-strand conformational polymorphism
    • Tsai M, Hanson N, Bignell M, Schwichtenberg K. Simultaneous detection and screening of T833C and G919A mutations of the cystathionine β-synthase gene by single-strand conformational polymorphism. Clin Biochem 1996;29:473-477
    • (1996) Clin Biochem , vol.29 , pp. 473-477
    • Tsai, M.1    Hanson, N.2    Bignell, M.3    Schwichtenberg, K.4
  • 101
    • 0029068922 scopus 로고
    • The molecular basis of homocystinuria due to cystathionine β-synthase deficiency in Italian families, and report of four novel mutations
    • Sebastio G, Sperandeo M, Panico M, et al. The molecular basis of homocystinuria due to cystathionine β-synthase deficiency in Italian families, and report of four novel mutations. Am J Hum Genet 1995;56:1324-1333
    • (1995) Am J Hum Genet , vol.56 , pp. 1324-1333
    • Sebastio, G.1    Sperandeo, M.2    Panico, M.3
  • 102
    • 0029852838 scopus 로고    scopus 로고
    • A 68-bp insertion found in a homocystinuric patient is a common variant and is skipped by alternative splicing of the cystathionine β-synthase mRNA
    • Sperandeo M, De Franchis R, Andria G, Sebastio G. A 68-bp insertion found in a homocystinuric patient is a common variant and is skipped by alternative splicing of the cystathionine β-synthase mRNA (letter). Am J Hum Genet 1996; 59:1391-1393
    • (1996) Am J Hum Genet , vol.59 , pp. 1391-1393
    • Sperandeo, M.1    De Franchis, R.2    Andria, G.3    Sebastio, G.4
  • 103
    • 0029829735 scopus 로고    scopus 로고
    • High prevalence of a mutation in the cystathionine β-synthase gene
    • Tsai M, Bignell M, Schwichtenberg K, Hanson N. High prevalence of a mutation in the cystathionine β-synthase gene. Am J Hum Genet 1996;59:1262-1267
    • (1996) Am J Hum Genet , vol.59 , pp. 1262-1267
    • Tsai, M.1    Bignell, M.2    Schwichtenberg, K.3    Hanson, N.4
  • 104
    • 85038156641 scopus 로고    scopus 로고
    • Prevalence of the T833/68 bp INS mutation in cystathionine β-synthase gene in different ethnic groups
    • Abst
    • Comeglio P, Pepe G, Camacho-Vanegas O, et al. Prevalence of the T833/68 bp INS mutation in cystathionine β-synthase gene in different ethnic groups. Thromb Res 1998;91(Suppl 1):S87 (Abst)
    • (1998) Thromb Res , vol.91 , Issue.SUPPL. 1
    • Comeglio, P.1    Pepe, G.2    Camacho-Vanegas, O.3
  • 105
    • 0028304102 scopus 로고
    • Human methylenetetrahydrofolate reductase isolation of cDNA, mappng and mutation identification
    • Goyette P, Sumner J, Milos R, et al. Human methylenetetrahydrofolate reductase isolation of cDNA, mappng and mutation identification. Nature Genet 1994;7:195-200
    • (1994) Nature Genet , vol.7 , pp. 195-200
    • Goyette, P.1    Sumner, J.2    Milos, R.3
  • 106
    • 84966175321 scopus 로고
    • Human methylenetetrahydrofolate reductase isolation of cDNA, mapping and mutation identification, Errata
    • Goyette P, Sumner J, Milos R, et al. Human methylenetetrahydrofolate reductase isolation of cDNA, mapping and mutation identification, Errata. Nature Genet 1994;7:551
    • (1994) Nature Genet , vol.7 , pp. 551
    • Goyette, P.1    Sumner, J.2    Milos, R.3
  • 107
    • 0026034240 scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease
    • Kang S, Wong P, Susmano A, et al. Thermolabile methylenetetrahydrofolate reductase: An inherited risk factor for coronary artery disease. Am J Hum Genet 1991;48:536-545
    • (1991) Am J Hum Genet , vol.48 , pp. 536-545
    • Kang, S.1    Wong, P.2    Susmano, A.3
  • 109
    • 0005775025 scopus 로고    scopus 로고
    • The incidence of the gene for thermolabile methylene tetrahydrofolate reductase in African Americans
    • McAndrew P, Brandt J, Pearl, Prior T. The incidence of the gene for thermolabile methylene tetrahydrofolate reductase in African Americans. Thromb Res 1996;83:195-198
    • (1996) Thromb Res , vol.83 , pp. 195-198
    • McAndrew, P.1    Brandt, J.2    Pearl3    Prior, T.4
  • 110
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques P, Bostom A, Williams R, et al. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 1996;93:7-9
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.1    Bostom, A.2    Williams, R.3
  • 111
    • 0029806746 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
    • Ma J, Stampfer M, Hennekens C, et al. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 1996;94:2410-2416
    • (1996) Circulation , vol.94 , pp. 2410-2416
    • Ma, J.1    Stampfer, M.2    Hennekens, C.3
  • 112
    • 85038156806 scopus 로고    scopus 로고
    • The mutant C677-T of the MTHFR gene is not a risk factor for thrombosis
    • Abst
    • Pinto G, Galleni A, De Cassan P, Barone E, Perroni L. The mutant C677-T of the MTHFR gene is not a risk factor for thrombosis. Thromb Res 1998;91:S30(Abst)
    • (1998) Thromb Res , vol.91
    • Pinto, G.1    Galleni, A.2    De Cassan, P.3    Barone, E.4    Perroni, L.5
  • 113
  • 114
    • 0023201968 scopus 로고
    • 12-responsive neonatal megaloblastic anemia and homocystinuria with associated reduced methionine synthase activity
    • 12-responsive neonatal megaloblastic anemia and homocystinuria with associated reduced methionine synthase activity. Blood 1987;69:1128-1133
    • (1987) Blood , vol.69 , pp. 1128-1133
    • Hallam, L.1    Sawyer, M.2    Clark, A.3    Van der Weyden, M.4
  • 115
    • 0030769174 scopus 로고    scopus 로고
    • Functional methionine synthase deficiency due to cblG disorder: A report of two patients and a review
    • Harding C, Arnold G, Barness L, Wolff J, Rosenblatt D. Functional methionine synthase deficiency due to cblG disorder: A report of two patients and a review. Am J Med Genet 1997;71:384-390
    • (1997) Am J Med Genet , vol.71 , pp. 384-390
    • Harding, C.1    Arnold, G.2    Barness, L.3    Wolff, J.4    Rosenblatt, D.5
  • 116
    • 0030825907 scopus 로고    scopus 로고
    • Folate-responsive homocystinuria and megaloblastic anaemia in a female patient with functional methionine synthase deficiency (cblE disease)
    • Fowler B, Schutgens R, Rosenblatt D, Smit G, Lindemans J. Folate-responsive homocystinuria and megaloblastic anaemia in a female patient with functional methionine synthase deficiency (cblE disease). J Inherit Metab Dis 1997;20:731-741
    • (1997) J Inherit Metab Dis , vol.20 , pp. 731-741
    • Fowler, B.1    Schutgens, R.2    Rosenblatt, D.3    Smit, G.4    Lindemans, J.5
  • 117
    • 0030843127 scopus 로고    scopus 로고
    • Clinical heterogeneity and prognosis in combined methylmalonic aciduria and homocystinuria (cblC)
    • Rosenblatt D, Aspler A, Shevell M, et al. Clinical heterogeneity and prognosis in combined methylmalonic aciduria and homocystinuria (cblC). J Inherit Metab Dis 1997;20:528-538
    • (1997) J Inherit Metab Dis , vol.20 , pp. 528-538
    • Rosenblatt, D.1    Aspler, A.2    Shevell, M.3
  • 118
    • 0029803594 scopus 로고    scopus 로고
    • Defects in human methionine synthase in cblG patients
    • Gulati S, Baker P, Li Y, et al. Defects in human methionine synthase in cblG patients. Hum Mol Genet 1996;5:1859-1865
    • (1996) Hum Mol Genet , vol.5 , pp. 1859-1865
    • Gulati, S.1    Baker, P.2    Li, Y.3
  • 119
    • 2642676850 scopus 로고    scopus 로고
    • Major lifestyle determinants of plasma total homocysteine distribution: The Hordaland homocysteine study
    • Nygard O, Refsum H, Ueland P, Vollset S. Major lifestyle determinants of plasma total homocysteine distribution: The Hordaland homocysteine study. Am J Clin Nutr 1998;67:263-270
    • (1998) Am J Clin Nutr , vol.67 , pp. 263-270
    • Nygard, O.1    Refsum, H.2    Ueland, P.3    Vollset, S.4
  • 120
    • 0028950274 scopus 로고
    • Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid
    • Landgren F, Israelsson B, Lindgren A, et al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Intern Med 1995;237:196-199
    • (1995) J Intern Med , vol.237 , pp. 196-199
    • Landgren, F.1    Israelsson, B.2    Lindgren, A.3
  • 121
    • 0032555096 scopus 로고    scopus 로고
    • Homocysteine, vitamins, and cardiovascular disease
    • Kuller L, Evans R. Homocysteine, vitamins, and cardiovascular disease. Circulation 1998;98:196-199
    • (1998) Circulation , vol.98 , pp. 196-199
    • Kuller, L.1    Evans, R.2
  • 122
    • 0031457858 scopus 로고    scopus 로고
    • Homocyst(e)ine and risk of cardiovascular disease in the multiple risk factor intervention trial
    • Evans R, Shaten J, Hempel J, Cutler J, Kuller L, for the MRFIT Research Group. Homocyst(e)ine and risk of cardiovascular disease in the multiple risk factor intervention trial. Arteriosclerosis Thromb Vasc Biol 1997;17:1947-1953
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 1947-1953
    • Evans, R.1    Shaten, J.2    Hempel, J.3    Cutler, J.4    Kuller, L.5
  • 123
    • 0032555167 scopus 로고    scopus 로고
    • Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins
    • Folsom A, Nieto F, McGovern P, et al. Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins. Circulation 1998;98:204-210
    • (1998) Circulation , vol.98 , pp. 204-210
    • Folsom, A.1    Nieto, F.2    McGovern, P.3
  • 124
    • 0026520124 scopus 로고
    • Hyperhomocyst(e)inemia: An independent risk factor for claudication
    • Molgaard J, Malinow M, Lassvik C, et al. Hyperhomocyst(e)inemia: An independent risk factor for claudication. J Intern Med 1992;231:273-279
    • (1992) J Intern Med , vol.231 , pp. 273-279
    • Molgaard, J.1    Malinow, M.2    Lassvik, C.3
  • 125
    • 0028855901 scopus 로고
    • Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease
    • Robinson K, Mayer E, Miller D, et al. Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. Circulation 1995;92:2825-2830
    • (1995) Circulation , vol.92 , pp. 2825-2830
    • Robinson, K.1    Mayer, E.2    Miller, D.3
  • 126
    • 0032481152 scopus 로고    scopus 로고
    • 6 from diet and supplements in relation to risk of coronary heart disease among women
    • 6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA 1998;279:359-364
    • (1998) JAMA , vol.279 , pp. 359-364
    • Rimm, E.1    Willett, W.2    Hu, F.3
  • 127
    • 17344370074 scopus 로고    scopus 로고
    • Vitamin supplementation reduces blood homocysteine levels. A controlled trial in patients with venous thrombosis and healthy volunteers
    • den Heijer M, Brouwer I, Bos G, et al. Vitamin supplementation reduces blood homocysteine levels. A controlled trial in patients with venous thrombosis and healthy volunteers. Arteriosclerosis Thromb Vasc Biol 1998;18;356-361
    • (1998) Arteriosclerosis Thromb Vasc Biol , vol.18 , pp. 356-361
    • Den Heijer, M.1    Brouwer, I.2    Bos, G.3
  • 128
    • 0031754849 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is a risk factor of recurrent venous thromboembolism
    • Eichinger S, Stumpflen A, Hirschl M, et al. Hyperhomocysteinemia is a risk factor of recurrent venous thromboembolism. Thromb Haemost 1998;80:566-569
    • (1998) Thromb Haemost , vol.80 , pp. 566-569
    • Eichinger, S.1    Stumpflen, A.2    Hirschl, M.3
  • 129
    • 17344369482 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia and a common methylenetetrahydrofolate reductase mutation (Ala223Val MTHFR) in patients with inherited thrombophilic coagulation defects
    • Legnani C, Palareti G, Grauso F, et al. Hyperhomocyst(e)inemia and a common methylenetetrahydrofolate reductase mutation (Ala223Val MTHFR) in patients with inherited thrombophilic coagulation defects. Arteriosclerosis Thromb Vasc Biol 1997;17:2924-2929
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 2924-2929
    • Legnani, C.1    Palareti, G.2    Grauso, F.3
  • 130
    • 0032521543 scopus 로고    scopus 로고
    • Homozygous cystathionine β-synthase deficiency, combined with Factor V Leiden or thermolabile methylenetetrahydrofolate reductase in the risk of venous thrombosis
    • Kluijtmans L, Boers G, Verbruggen B, et al. Homozygous cystathionine β-synthase deficiency, combined with Factor V Leiden or thermolabile methylenetetrahydrofolate reductase in the risk of venous thrombosis. Blood 1998;91:2015-2018
    • (1998) Blood , vol.91 , pp. 2015-2018
    • Kluijtmans, L.1    Boers, G.2    Verbruggen, B.3
  • 131
    • 0030975769 scopus 로고    scopus 로고
    • The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes
    • Malinow M, Nieto F, Kruger W, et al. The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes. Arteriosclerosis Thromb Vasc Biol 1997;17:1157-1162
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 1157-1162
    • Malinow, M.1    Nieto, F.2    Kruger, W.3
  • 132
    • 0030934392 scopus 로고    scopus 로고
    • Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease
    • Christensen B, Frosst P, Lussier-Cacan S, et al. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease. Arteriosclerosis Thromb Vasc Biol 1997;17:569-573
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 569-573
    • Christensen, B.1    Frosst, P.2    Lussier-Cacan, S.3
  • 133
    • 0030868732 scopus 로고    scopus 로고
    • The relationship between MTHFR genotype, serum homocysteine and folate levels
    • Ali N, Powell J, Swaminathan R, Markus H. The relationship between MTHFR genotype, serum homocysteine and folate levels. Biochem Soc Trans 1997;25:386S
    • (1997) Biochem Soc Trans , vol.25
    • Ali, N.1    Powell, J.2    Swaminathan, R.3    Markus, H.4
  • 134
    • 0032485522 scopus 로고    scopus 로고
    • 677C to T mutation in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene and plasma homocyst(e)ine levels in patients with TIA or minor stroke
    • Lalouschek W, Aull S, Kominger L, et al. 677C to T mutation in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene and plasma homocyst(e)ine levels in patients with TIA or minor stroke. Neurol Sci 1998;155:156-162
    • (1998) Neurol Sci , vol.155 , pp. 156-162
    • Lalouschek, W.1    Aull, S.2    Kominger, L.3
  • 135
    • 85038163099 scopus 로고    scopus 로고
    • Increased thrombotic risk for patients with associated 844ins68 mutation of the CBS gene and the 677C-T mutation of the MTHFR gene
    • Abst
    • de Franchis R, Buoninconti A, Fermo I, et al. Increased thrombotic risk for patients with associated 844ins68 mutation of the CBS gene and the 677C-T mutation of the MTHFR gene. Thromb Res 1998;91 (Suppl 1):S3 (Abst)
    • (1998) Thromb Res , vol.91 , Issue.SUPPL. 1
    • De Franchis, R.1    Buoninconti, A.2    Fermo, I.3
  • 136
    • 0031821779 scopus 로고    scopus 로고
    • Homocysteine and vitamins in cardiovascular disease
    • Jacobsen D. Homocysteine and vitamins in cardiovascular disease. Clin Chem 1998;44:1833-1843
    • (1998) Clin Chem , vol.44 , pp. 1833-1843
    • Jacobsen, D.1
  • 138
    • 0031825121 scopus 로고    scopus 로고
    • Relationship between homocysteine and thrombotic disease
    • Selhub J, D'Angelo A. Relationship between homocysteine and thrombotic disease. Am J Med Sci 1998;316:129-141
    • (1998) Am J Med Sci , vol.316 , pp. 129-141
    • Selhub, J.1    D'Angelo, A.2
  • 139
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch G, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 1998;338:1042-1050
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.1    Loscalzo, J.2
  • 140
    • 0030610779 scopus 로고    scopus 로고
    • Minireview Homocysteine and vascular dysfunction
    • Lentz S. Minireview Homocysteine and vascular dysfunction. Life Sciences 1997;61:1205-1215
    • (1997) Life Sciences , vol.61 , pp. 1205-1215
    • Lentz, S.1
  • 141
    • 0027531427 scopus 로고
    • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
    • Stamler J, Osborne J, Jaraki O, et al. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest 1993;91:308-318
    • (1993) J Clin Invest , vol.91 , pp. 308-318
    • Stamler, J.1    Osborne, J.2    Jaraki, O.3
  • 142
    • 0030119805 scopus 로고    scopus 로고
    • Homocysteine and hemostasis: Pathogenetic mechanisms predisposing to thrombosis
    • Harpel P, Zhang X, Borth W. Homocysteine and hemostasis: Pathogenetic mechanisms predisposing to thrombosis. J Nutr 1996;126:1285S-1289S
    • (1996) J Nutr , vol.126
    • Harpel, P.1    Zhang, X.2    Borth, W.3
  • 143
    • 0027361575 scopus 로고
    • Homocystinuria: Clinical and pathologic review, with emphasis on thrombotic features, including pulmonary artery thrombosis
    • Landing B, Haust M, Bernstein J, et al, eds: Genetic Metabolic Diseases. Basel: Karger
    • Lieberman E, Gomperts E, Shaw K, Landing B, Donnell G. Homocystinuria: Clinical and pathologic review, with emphasis on thrombotic features, including pulmonary artery thrombosis. In: Landing B, Haust M, Bernstein J, et al, eds: Genetic Metabolic Diseases. Perspect Pediatr Pathol. Basel: Karger, 1993:125-147
    • (1993) Perspect Pediatr Pathol , pp. 125-147
    • Lieberman, E.1    Gomperts, E.2    Shaw, K.3    Landing, B.4    Donnell, G.5
  • 144
    • 0031035742 scopus 로고    scopus 로고
    • Metabolism of homocysteine thiolactone in human cell cultures. Possible mechanism for pathological consequences of elevated homocysteine levels
    • Jakubowski H. Metabolism of homocysteine thiolactone in human cell cultures. Possible mechanism for pathological consequences of elevated homocysteine levels. J Biol Chem 1997;272:1935-1942
    • (1997) J Biol Chem , vol.272 , pp. 1935-1942
    • Jakubowski, H.1
  • 145
    • 0029866820 scopus 로고    scopus 로고
    • Homocysteine, EDRF and endothelial function
    • Upchurch GJ, Welch G, Loscalzo J. Homocysteine, EDRF and endothelial function. J Nutr 1996;126:1290S-1294S
    • (1996) J Nutr , vol.126
    • Upchurch, G.J.1    Welch, G.2    Loscalzo, J.3
  • 146
    • 1842411860 scopus 로고    scopus 로고
    • Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase
    • Upchurch GJ, Welch G, Fabian A, et al. Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase. J Biol Chem 1997;272:17012-17017
    • (1997) J Biol Chem , vol.272 , pp. 17012-17017
    • Upchurch, G.J.1    Welch, G.2    Fabian, A.3
  • 147
    • 0022552919 scopus 로고
    • Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
    • Starkebaum G, Harlan J. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 1986;77:1370-1376
    • (1986) J Clin Invest , vol.77 , pp. 1370-1376
    • Starkebaum, G.1    Harlan, J.2
  • 148
    • 0014859783 scopus 로고
    • Production of arteriosclerosis by homocysteinemia
    • McCully K, Ragsdale B. Production of arteriosclerosis by homocysteinemia. Am J Pathol 1970;61:1-8
    • (1970) Am J Pathol , vol.61 , pp. 1-8
    • McCully, K.1    Ragsdale, B.2
  • 149
    • 0016743933 scopus 로고
    • Homocysteine theory of arteriosclerosis
    • McCully K, Wilson R. Homocysteine theory of arteriosclerosis. Atherosclerosis 1975;22:215-227
    • (1975) Atherosclerosis , vol.22 , pp. 215-227
    • McCully, K.1    Wilson, R.2
  • 150
    • 0021041780 scopus 로고
    • Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons
    • Harker L, Harian J, Ross R. Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons. Circ Res 1983;53:731-739
    • (1983) Circ Res , vol.53 , pp. 731-739
    • Harker, L.1    Harian, J.2    Ross, R.3
  • 151
    • 0027092328 scopus 로고
    • Endothelium-derived relaxing factor modulates the atherothrombogenic effects of homocysteine
    • Stamler J, Loscalzo J. Endothelium-derived relaxing factor modulates the atherothrombogenic effects of homocysteine. J Cardiol Pharmacol 1992;20:S202-S204
    • (1992) J Cardiol Pharmacol , vol.20
    • Stamler, J.1    Loscalzo, J.2
  • 152
    • 0009630196 scopus 로고
    • The effects of homocysteine in endothelial nitric oxide production
    • Abst
    • Upchurch GJ, Welch G, Ramdev M, et al. The effects of homocysteine in endothelial nitric oxide production. FASEB Lett 1995;9:A876(Abst)
    • (1995) FASEB Lett , vol.9
    • Upchurch, G.J.1    Welch, G.2    Ramdev, M.3
  • 153
    • 0028948446 scopus 로고
    • Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia
    • Blom H, Kleinveld H, Boers G, et al. Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia. Eur J Clin Invest 1995;25:149-154
    • (1995) Eur J Clin Invest , vol.25 , pp. 149-154
    • Blom, H.1    Kleinveld, H.2    Boers, G.3
  • 154
    • 0020520336 scopus 로고
    • Endothelial cell dysfunction in homocystinuria
    • de Groot P, Willems C, Boers G, et al. Endothelial cell dysfunction in homocystinuria. Eur J Clin Invest 1983;13:405-410
    • (1983) Eur J Clin Invest , vol.13 , pp. 405-410
    • De Groot, P.1    Willems, C.2    Boers, G.3
  • 155
    • 0027255291 scopus 로고
    • Impaired endotheial function occurs in the systemic arteries of children with homozygous homocytinuria but not in their heterozygous parents
    • Celermajer D, Sorensen K, Ryalls M, et al. Impaired endotheial function occurs in the systemic arteries of children with homozygous homocytinuria but not in their heterozygous parents. J Am Coll Cardiol 1993;22:854-858
    • (1993) J Am Coll Cardiol , vol.22 , pp. 854-858
    • Celermajer, D.1    Sorensen, K.2    Ryalls, M.3
  • 156
    • 0031018333 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans
    • Tawakol A, Omland P, Gerhard M, Wu J, Creager M. Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation 1997;95:1119-1121
    • (1997) Circulation , vol.95 , pp. 1119-1121
    • Tawakol, A.1    Omland, P.2    Gerhard, M.3    Wu, J.4    Creager, M.5
  • 157
    • 0030876147 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunction in humans
    • Woo K, Chook P, Lolin Y, et al. Hyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunction in humans. Circulation 1997;96:2542-2544
    • (1997) Circulation , vol.96 , pp. 2542-2544
    • Woo, K.1    Chook, P.2    Lolin, Y.3
  • 158
    • 0028298171 scopus 로고
    • Promotion of vascular smooth muscle cell growth by homocysteine: A link to atherosclerosis
    • Tsai J, Perrella M, Yoshizumi M, et al. Promotion of vascular smooth muscle cell growth by homocysteine: A link to atherosclerosis. Proc Natl Acad Sci USA 1994;91:6369-6373
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6369-6373
    • Tsai, J.1    Perrella, M.2    Yoshizumi, M.3
  • 159
    • 13344270367 scopus 로고    scopus 로고
    • Induction of cyclin A gene expressin by homocysteine in vascular smooth muscle cells
    • Tsai J-C, Wang H, Perrella M, et al. Induction of cyclin A gene expressin by homocysteine in vascular smooth muscle cells. J Clin Invest 1996;97:146-153
    • (1996) J Clin Invest , vol.97 , pp. 146-153
    • Tsai, J.-C.1    Wang, H.2    Perrella, M.3
  • 160
    • 0031965641 scopus 로고    scopus 로고
    • Homocysteine-induced nitric oxide production in vascular smooth muscle cells by NF-kB dependent transcriptional activation of Nos 2
    • Welch G, Upchurch G, Farivar R, et al. Homocysteine-induced nitric oxide production in vascular smooth muscle cells by NF-kB dependent transcriptional activation of Nos 2. Proc Am Assoc Phys 1998;110:22-31
    • (1998) Proc Am Assoc Phys , vol.110 , pp. 22-31
    • Welch, G.1    Upchurch, G.2    Farivar, R.3
  • 161
    • 17344368557 scopus 로고    scopus 로고
    • Homocysteine as a risk factor for vascular disease. Enhanced collagen production and accumulation by smooth muscle cells
    • Majors A, Ehrhart L, Pezacka E. Homocysteine as a risk factor for vascular disease. Enhanced collagen production and accumulation by smooth muscle cells. Arteriosclerosis Thromb Vasc Biol 1997;17:2074-2081
    • (1997) Arteriosclerosis Thromb Vasc Biol , vol.17 , pp. 2074-2081
    • Majors, A.1    Ehrhart, L.2    Pezacka, E.3
  • 162
    • 0030610589 scopus 로고    scopus 로고
    • ras methylation in vascular endothelial cells by homocysteine but not cysteine
    • ras methylation in vascular endothelial cells by homocysteine but not cysteine. J Biol Chem 1997;272:25380-25385
    • (1997) J Biol Chem , vol.272 , pp. 25380-25385
    • Wang, H.1    Yoshizumi, M.2    Lai, K.3
  • 163
    • 0027493344 scopus 로고
    • Chemical pathology of homocysteine I. Atherogenesis
    • McCully K. Chemical pathology of homocysteine I. Atherogenesis. Ann Clin Lab Sci 1993;23:477-493
    • (1993) Ann Clin Lab Sci , vol.23 , pp. 477-493
    • McCully, K.1
  • 164
    • 0000726206 scopus 로고    scopus 로고
    • Homocysteine modulates the expression of a specific cytokine (monocyte chemoattractant protein-I) in human aortic endothelial cells
    • Abst
    • Poddar R, Sivasubramanian N, Robinson K, Jacobsen D. Homocysteine modulates the expression of a specific cytokine (monocyte chemoattractant protein-I) in human aortic endothelial cells. Circulation 1997;96:I-286, (Abst)
    • (1997) Circulation , vol.96
    • Poddar, R.1    Sivasubramanian, N.2    Robinson, K.3    Jacobsen, D.4
  • 165
    • 0017197285 scopus 로고
    • Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response in its genesis
    • Harker L, Ross R, Slichter S, Scott C. Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response in its genesis. J Clin Invest 1976:58:731-741
    • (1976) J Clin Invest , vol.58 , pp. 731-741
    • Harker, L.1    Ross, R.2    Slichter, S.3    Scott, C.4
  • 166
    • 0027247803 scopus 로고
    • Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism
    • Di Minno G, Davi G, Margaglione M, et al. Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism. J Clin Invest 1993;92:1400-1406
    • (1993) J Clin Invest , vol.92 , pp. 1400-1406
    • Di Minno, G.1    Davi, G.2    Margaglione, M.3
  • 167
    • 0014434483 scopus 로고
    • Activation of Hagemann factor by L-homocystine
    • Ratnoff O. Activation of Hagemann factor by L-homocystine. Science 1968;162:1007-1009
    • (1968) Science , vol.162 , pp. 1007-1009
    • Ratnoff, O.1
  • 168
    • 0025190042 scopus 로고
    • Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells
    • Rodgers G, Conn M. Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells. Blood 1990;75:895-901
    • (1990) Blood , vol.75 , pp. 895-901
    • Rodgers, G.1    Conn, M.2
  • 169
    • 0027250615 scopus 로고
    • Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells
    • Fryer R, Wilson B, Gubler D, Fitzgerald L, Rodgers G. Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells. Arteriosclerosis Thromb Vasc Biol 1993;13:405-410
    • (1993) Arteriosclerosis Thromb Vasc Biol , vol.13 , pp. 405-410
    • Fryer, R.1    Wilson, B.2    Gubler, D.3    Fitzgerald, L.4    Rodgers, G.5
  • 170
    • 0027319970 scopus 로고
    • Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells
    • Nishinaga M, Ozawa T, Shimada K. Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest 1993;92:1381-1386
    • (1993) J Clin Invest , vol.92 , pp. 1381-1386
    • Nishinaga, M.1    Ozawa, T.2    Shimada, K.3
  • 171
    • 0032540276 scopus 로고    scopus 로고
    • Tissue plasminogen activator binding to the annexin II tail domain
    • Hajjar K, Mauri L, Jacovina A, et al. Tissue plasminogen activator binding to the annexin II tail domain. J Biol Chem 1998; 273:9987-9993
    • (1998) J Biol Chem , vol.273 , pp. 9987-9993
    • Hajjar, K.1    Mauri, L.2    Jacovina, A.3
  • 172
    • 0026345948 scopus 로고
    • Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
    • Lentz S, Sadler J. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest 1991;88:1906-1914
    • (1991) J Clin Invest , vol.88 , pp. 1906-1914
    • Lentz, S.1    Sadler, J.2
  • 173
    • 0031452131 scopus 로고    scopus 로고
    • Platelet and monocyte variables in homocystinuria due to cystathionine-beta-synthase deficiency
    • Coppola A, Albisinni R, Madonna P, et al. Platelet and monocyte variables in homocystinuria due to cystathionine-beta-synthase deficiency. Haematologica 1997;92:189-90
    • (1997) Haematologica , vol.92 , pp. 189-190
    • Coppola, A.1    Albisinni, R.2    Madonna, P.3
  • 174
    • 0032499126 scopus 로고    scopus 로고
    • Reduction of plasma homocyst(e)ine levels by breakfast cereal fortified with folic acid in patients with coronary heart disease
    • Malinow M, Duell P, Hess D, et al. Reduction of plasma homocyst(e)ine levels by breakfast cereal fortified with folic acid in patients with coronary heart disease. N Engl J Med 1998;338:1009-1115
    • (1998) N Engl J Med , vol.338 , pp. 1009-1115
    • Malinow, M.1    Duell, P.2    Hess, D.3
  • 175
    • 0031572492 scopus 로고    scopus 로고
    • Homocysteine levels and cardiovascular disease
    • Stampfer M. Homocysteine levels and cardiovascular disease. Am Family Phys 1997;56:1568, 1571-1572
    • (1997) Am Family Phys , vol.56 , pp. 1568
    • Stampfer, M.1
  • 176
    • 0029995348 scopus 로고    scopus 로고
    • Vitamins as homocysteine-lowering agents
    • Brattstrom L. Vitamins as homocysteine-lowering agents. J Nutr 1996;126:1276S-1280S
    • (1996) J Nutr , vol.126
    • Brattstrom, L.1
  • 177
    • 0028957460 scopus 로고
    • Hyperhomocysteinemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease
    • Van den Berg M, Boers G, Franken D, et al. Hyperhomocysteinemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease. Eur J Clin Invest 1995;25:176-181
    • (1995) Eur J Clin Invest , vol.25 , pp. 176-181
    • Van den Berg, M.1    Boers, G.2    Franken, D.3
  • 178
    • 0028567843 scopus 로고
    • Coagulation factors and markers of activation of coagulation in homocystinuria (HOCY): A study in two siblings
    • Schienle H, Seitz R, Rohner I, et al. Coagulation factors and markers of activation of coagulation in homocystinuria (HOCY): A study in two siblings. Blood Coag Fibrinolysis 1994;5:873-878
    • (1994) Blood Coag Fibrinolysis , vol.5 , pp. 873-878
    • Schienle, H.1    Seitz, R.2    Rohner, I.3
  • 179
    • 1842298689 scopus 로고    scopus 로고
    • Levels of prothrombin fragment F1+2 in patients with hyperhomocysteinemia and a history of venous thromboembolism
    • Kyrle PA, Stumpflen A, Hirschl M, et al. Levels of prothrombin fragment F1+2 in patients with hyperhomocysteinemia and a history of venous thromboembolism. Thromb Haemost 1997;78:1327-1231
    • (1997) Thromb Haemost , vol.78 , pp. 1327-1231
    • Kyrle, P.A.1    Stumpflen, A.2    Hirschl, M.3
  • 180
    • 0031816123 scopus 로고    scopus 로고
    • Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
    • Jacob R, Gretz D, Taylor P, et al. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J Nutr 1998;128:1204-1212
    • (1998) J Nutr , vol.128 , pp. 1204-1212
    • Jacob, R.1    Gretz, D.2    Taylor, P.3
  • 181
    • 19244377848 scopus 로고    scopus 로고
    • Effect of B-group vitamins and antioxidant vitamins on hyperhomocysteinemia: A double-blind, randomized, factorial-design, controlled trial
    • Woodside J, Yamell J, McMaster D, et al. Effect of B-group vitamins and antioxidant vitamins on hyperhomocysteinemia: A double-blind, randomized, factorial-design, controlled trial. Am J Clin Nutr 1998;67:858-866
    • (1998) Am J Clin Nutr , vol.67 , pp. 858-866
    • Woodside, J.1    Yamell, J.2    McMaster, D.3


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