-
1
-
-
0014545138
-
Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
-
McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol 1969;56:111-28.
-
(1969)
Am J Pathol
, vol.56
, pp. 111-128
-
-
McCully, K.S.1
-
2
-
-
0024342063
-
Plasma homocysteine, a risk factor for vascular disease: Plasma levels in health, disease, and drug therapy
-
Ueland PM, Refsum H. Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy. J Lab Clin Med 1989;114:473-501.
-
(1989)
J Lab Clin Med
, vol.114
, pp. 473-501
-
-
Ueland, P.M.1
Refsum, H.2
-
3
-
-
0029939676
-
Homocysteine and vascular disease
-
McCully KS. Homocysteine and vascular disease. Nat Med 1996;2:386-9.
-
(1996)
Nat Med
, vol.2
, pp. 386-389
-
-
McCully, K.S.1
-
4
-
-
0026633925
-
Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease
-
Kang SS, Wong PW, Malinow MR. Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease. Ann Rev Nutr 1992;12:279-98.
-
(1992)
Ann Rev Nutr
, vol.12
, pp. 279-298
-
-
Kang, S.S.1
Wong, P.W.2
Malinow, M.R.3
-
5
-
-
0026684554
-
A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians
-
Stampfer MJ, Malinow MR, Willett WC, et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA 1992;268:877-81.
-
(1992)
JAMA
, vol.268
, pp. 877-881
-
-
Stampfer, M.J.1
Malinow, M.R.2
Willett, W.C.3
-
6
-
-
0027293835
-
Total homocysteine in plasma or serum: Methods and clinical applications
-
Ueland PM, Refsum H, Stabler SP, Malinow MR, Andersson A, Allen RH. Total homocysteine in plasma or serum: methods and clinical applications. Clin Chem 1993;39:1764-79.
-
(1993)
Clin Chem
, vol.39
, pp. 1764-1779
-
-
Ueland, P.M.1
Refsum, H.2
Stabler, S.P.3
Malinow, M.R.4
Andersson, A.5
Allen, R.H.6
-
7
-
-
0023732986
-
Methionine metabolism in mammals: The methionine-sparing effect of cystine
-
Finkelstein JD, Martin JJ, Harris BJ. Methionine metabolism in mammals: the methionine-sparing effect of cystine. J Biol Chem 1988;263:11750-4.
-
(1988)
J Biol Chem
, vol.263
, pp. 11750-11754
-
-
Finkelstein, J.D.1
Martin, J.J.2
Harris, B.J.3
-
8
-
-
0029257541
-
Homocysteine species as components of plasma redox thiol status
-
Ueland PM. Homocysteine species as components of plasma redox thiol status. Clin Chem 1995;41:340-2.
-
(1995)
Clin Chem
, vol.41
, pp. 340-342
-
-
Ueland, P.M.1
-
9
-
-
0028284362
-
Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: Sex differences and correlation with cobalamin and folate concentrations in healthy subjects
-
Jacobsen DW, Gatautis VJ, Green R, et al. Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex differences and correlation with cobalamin and folate concentrations in healthy subjects. Clin Chem 1994;40:873-81.
-
(1994)
Clin Chem
, vol.40
, pp. 873-881
-
-
Jacobsen, D.W.1
Gatautis, V.J.2
Green, R.3
-
10
-
-
0027198477
-
Disordered methionine/homocysteine metabolism in premature vascular disease: Its occurrence, cofactor therapy, and enzymology
-
Dudman NP, Wilcken DE, Wang J, Lynch JF, Macey D, Lundberg P. Disordered methionine/homocysteine metabolism in premature vascular disease: its occurrence, cofactor therapy, and enzymology. Arterioscler Thromb 1993;13:1253-60.
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 1253-1260
-
-
Dudman, N.P.1
Wilcken, D.E.2
Wang, J.3
Lynch, J.F.4
Macey, D.5
Lundberg, P.6
-
11
-
-
0029827313
-
Homocysteine and risk of premature coronary disease: Evidence for a common gene mutation
-
Gallagher PM, Meleady R, Shields DC, et al. Homocysteine and risk of premature coronary disease: evidence for a common gene mutation. Circulation 1996;94:2154-8.
-
(1996)
Circulation
, vol.94
, pp. 2154-2158
-
-
Gallagher, P.M.1
Meleady, R.2
Shields, D.C.3
-
12
-
-
0000167774
-
Disorders of transsulfuration
-
Scriver CR, Beaudet AL, Sly WS, Valle D, eds. New York: McGraw-Hill
-
Mudd SH, Levy HL, Skovby F. Disorders of transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The metabolic and molecular bases of inherited disease. 7th ed. Vol. 1. New York: McGraw-Hill, 1995:1279-327.
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease. 7th Ed.
, vol.1
, pp. 1279-1327
-
-
Mudd, S.H.1
Levy, H.L.2
Skovby, F.3
-
13
-
-
0014310595
-
Homocystinuria. I. A clinical and pathological study of nine subjects in six families
-
Carey MC, Donovan DE, FitzGerald O, McAuley FD. Homocystinuria. I. A clinical and pathological study of nine subjects in six families. Am J Med 1968;45:7-25.
-
(1968)
Am J Med
, vol.45
, pp. 7-25
-
-
Carey, M.C.1
Donovan, D.E.2
FitzGerald, O.3
McAuley, F.D.4
-
14
-
-
0021894152
-
The natural history of homocystinuria due to cystathionine β-synthase deficiency
-
Mudd SH, Skovby F, Levy HL, et al. The natural history of homocystinuria due to cystathionine β-synthase deficiency. Am J Hum Genet 1985; 37:1-31.
-
(1985)
Am J Hum Genet
, vol.37
, pp. 1-31
-
-
Mudd, S.H.1
Skovby, F.2
Levy, H.L.3
-
15
-
-
0024391453
-
Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease
-
Malinow MR, Kang SS, Taylor LM, et al. Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease. Circulation 1989;79:1180-8.
-
(1989)
Circulation
, vol.79
, pp. 1180-1188
-
-
Malinow, M.R.1
Kang, S.S.2
Taylor, L.M.3
-
16
-
-
0025278455
-
Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke
-
Coull BM, Malinow MR, Beamer N, Sexton G, Nordt F, de Garmo P. Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke. Stroke 1990;21:572-6.
-
(1990)
Stroke
, vol.21
, pp. 572-576
-
-
Coull, B.M.1
Malinow, M.R.2
Beamer, N.3
Sexton, G.4
Nordt, F.5
De Garmo, P.6
-
17
-
-
0008034516
-
Homocyst(e)ine in daily practice: Levels in coronary heart disease
-
Malinow MR, Sexton G, Averbuch M, Grossman M, Wilson O, Upson B. Homocyst(e)ine in daily practice: levels in coronary heart disease. Coronary Artery Dis 1990;2:4-12.
-
(1990)
Coronary Artery Dis
, vol.2
, pp. 4-12
-
-
Malinow, M.R.1
Sexton, G.2
Averbuch, M.3
Grossman, M.4
Wilson, O.5
Upson, B.6
-
18
-
-
0015530475
-
Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity
-
Mudd SH, Uhlendorf BW, Freeman JM, Finkelstein ID, Shih VE. Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity. Biochem Biophys Res Commun 1972;46:905-12.
-
(1972)
Biochem Biophys Res Commun
, vol.46
, pp. 905-912
-
-
Mudd, S.H.1
Uhlendorf, B.W.2
Freeman, J.M.3
Finkelstein, I.D.4
Shih, V.E.5
-
19
-
-
0002194950
-
Inborn errors of folate metabolism
-
Blakely RL, Whitehead VM, eds. New York: Marcel Dekker
-
Erbe RW. Inborn errors of folate metabolism. In: Blakely RL, Whitehead VM, eds. Folate and pterins: nutritional, pharmacological, and physiological aspects. New York: Marcel Dekker, 1986:413-25.
-
(1986)
Folate and Pterins: Nutritional, Pharmacological, and Physiological Aspects
, pp. 413-425
-
-
Erbe, R.W.1
-
20
-
-
0030971062
-
Homocysteine and thrombotic disease
-
D'Angelo A, Selhub J. Homocysteine and thrombotic disease. Blood 1997;90:1-11.
-
(1997)
Blood
, vol.90
, pp. 1-11
-
-
D'Angelo, A.1
Selhub, J.2
-
21
-
-
0023696435
-
Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase
-
Kang SS, Zhou J, Wong PWK, Kowalisyn J, Strokosch G. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 1988;43:414-21.
-
(1988)
Am J Hum Genet
, vol.43
, pp. 414-421
-
-
Kang, S.S.1
Zhou, J.2
Wong, P.W.K.3
Kowalisyn, J.4
Strokosch, G.5
-
22
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-3.
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
-
23
-
-
0030610090
-
The mutation Ala677→Val in the methylene tetrahydrofolate reductase gene: A risk factor for arterial disease and venous thrombosis
-
Arruda VR, von Zuben PM, Chiaparini LC, Annichino-Bizzaccni JM, Costa FF. The mutation Ala677→Val in the methylene tetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis. Thromb Haemost 1997;77:818-21.
-
(1997)
Thromb Haemost
, vol.77
, pp. 818-821
-
-
Arruda, V.R.1
Von Zuben, P.M.2
Chiaparini, L.C.3
Annichino-Bizzaccni, J.M.4
Costa, F.F.5
-
24
-
-
0029806746
-
Methylenetetrahydrotolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians
-
Ma J, Stampfer MJ, Hennekens CH, et al. Methylenetetrahydrotolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Circulation 1996;94:2410-6.
-
(1996)
Circulation
, vol.94
, pp. 2410-2416
-
-
Ma, J.1
Stampfer, M.J.2
Hennekens, C.H.3
-
26
-
-
0030476385
-
Common mutation in methylenetetrahydrofolate reductase: Correlation with homocysteine metabolism and late-onset vascular disease
-
Deloughery TG, Evans A, Sadeghi A, et al. Common mutation in methylenetetrahydrofolate reductase: correlation with homocysteine metabolism and late-onset vascular disease. Circulation 1996;94:3074-8.
-
(1996)
Circulation
, vol.94
, pp. 3074-3078
-
-
Deloughery, T.G.1
Evans, A.2
Sadeghi, A.3
-
27
-
-
0023832738
-
12 deficiency than in heterozygosity for homocystinuria due to cystathionine β-synthase deficiency
-
12 deficiency than in heterozygosity for homocystinuria due to cystathionine β-synthase deficiency. Metabolism 1988;37:175-8.
-
(1988)
Metabolism
, vol.37
, pp. 175-178
-
-
Brattström, L.1
Israelsson, B.2
Lindgärde, F.3
Hultberg, B.4
-
28
-
-
0023243925
-
Homocysteinemia due to folate deficiency
-
Kang SS, Wong PWK, Norusis M. Homocysteinemia due to folate deficiency. Metabolism 1987;36:458-62.
-
(1987)
Metabolism
, vol.36
, pp. 458-462
-
-
Kang, S.S.1
Wong, P.W.K.2
Norusis, M.3
-
29
-
-
0023870112
-
Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry
-
Stabler SP, Marcell PD, Podell ER, Allen RH, Savage DG, Lindenbaum J. Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry. J Clin Invest 1988;81:466-74.
-
(1988)
J Clin Invest
, vol.81
, pp. 466-474
-
-
Stabler, S.P.1
Marcell, P.D.2
Podell, E.R.3
Allen, R.H.4
Savage, D.G.5
Lindenbaum, J.6
-
30
-
-
0027382008
-
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
-
Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993;270:2693-8.
-
(1993)
JAMA
, vol.270
, pp. 2693-2698
-
-
Selhub, J.1
Jacques, P.F.2
Wilson, P.W.3
Rush, D.4
Rosenberg, I.H.5
-
31
-
-
0018651563
-
Sulphur containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphide
-
Wilcken DE, Gupta VJ. Sulphur containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphide. Eur J Clin Invest 1979;9:301-7.
-
(1979)
Eur J Clin Invest
, vol.9
, pp. 301-307
-
-
Wilcken, D.E.1
Gupta, V.J.2
-
32
-
-
0027615819
-
Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients
-
Chauveau P, Chadefaux B, Coúde M, et al. Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients. Kidney Int Suppl 1993;41:S72-S77.
-
(1993)
Kidney Int Suppl
, vol.41
-
-
Chauveau, P.1
Chadefaux, B.2
Coúde, M.3
-
33
-
-
0028223165
-
Sensitivity of serum methylmalonic acid and total homocysteine determinants for diagnosing cobalamin and folate deficiencies
-
Savage DG, Lindenbaum J, Stabler SP, Allen RH. Sensitivity of serum methylmalonic acid and total homocysteine determinants for diagnosing cobalamin and folate deficiencies. Am J Med 1994;96:239-46.
-
(1994)
Am J Med
, vol.96
, pp. 239-246
-
-
Savage, D.G.1
Lindenbaum, J.2
Stabler, S.P.3
Allen, R.H.4
-
35
-
-
0026096815
-
Plasma homocysteine in children with acute lymphoblastic leukemia: Changes during a chemotherapeutic regimen including methotrexate
-
Refsum H, Wesenberg F, Ueland PM. Plasma homocysteine in children with acute lymphoblastic leukemia: changes during a chemotherapeutic regimen including methotrexate. Cancer Res 1991;51:828-35.
-
(1991)
Cancer Res
, vol.51
, pp. 828-835
-
-
Refsum, H.1
Wesenberg, F.2
Ueland, P.M.3
-
36
-
-
0001010968
-
Plasma homocysteine and cardiovascular disease
-
Francis RB Jr, ed. New York: Marcel Dekker
-
Ueland PM, Refsum H, Brattstrom L. Plasma homocysteine and cardiovascular disease. In: Francis RB Jr, ed. Atherosclerotic cardiovascular disease, hemostasis, and endothelial function. New York: Marcel Dekker, 1992:183-236.
-
(1992)
Atherosclerotic Cardiovascular Disease, Hemostasis, and Endothelial Function
, pp. 183-236
-
-
Ueland, P.M.1
Refsum, H.2
Brattstrom, L.3
-
38
-
-
0028788020
-
Total plasma homocysteine and cardiovascular risk profile: The Hordaland Homocysteine Study
-
Nygard O, Vollset SE, Refsum H, et al. Total plasma homocysteine and cardiovascular risk profile: the Hordaland Homocysteine Study. JAMA 1995;274:1526-33.
-
(1995)
JAMA
, vol.274
, pp. 1526-1533
-
-
Nygard, O.1
Vollset, S.E.2
Refsum, H.3
-
40
-
-
0028918123
-
Can lowering homocysteine levels reduce cardiovascular risk?
-
Stampfer MJ, Malinow MR. Can lowering homocysteine levels reduce cardiovascular risk? N Engl J Med 1995;332:328-9.
-
(1995)
N Engl J Med
, vol.332
, pp. 328-329
-
-
Stampfer, M.J.1
Malinow, M.R.2
-
41
-
-
0021998698
-
Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease
-
Boers GHJ, Smals AGH, Trijbels FJM, et al. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease. N Engl J Med 1985;313:709-15.
-
(1985)
N Engl J Med
, vol.313
, pp. 709-715
-
-
Boers, G.H.J.1
Smals, A.G.H.2
Trijbels, F.J.M.3
-
42
-
-
0025756673
-
Hyperhomocysteinemia: An independent risk factor for vascular disease
-
Clarke R, Daly L, Robinson K, et al. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med 1991;324:1149-55.
-
(1991)
N Engl J Med
, vol.324
, pp. 1149-1155
-
-
Clarke, R.1
Daly, L.2
Robinson, K.3
-
43
-
-
0029084552
-
Serum total homocysteine and coronary heart disease
-
Arnesen E, Refsum H, Bonaa KH, Ueland PM, Forde OH, Nordrehaug JE. Serum total homocysteine and coronary heart disease. Int J Epidemiol 1995;24:704-9.
-
(1995)
Int J Epidemiol
, vol.24
, pp. 704-709
-
-
Arnesen, E.1
Refsum, H.2
Bonaa, K.H.3
Ueland, P.M.4
Forde, O.H.5
Nordrehaug, J.E.6
-
44
-
-
0028219672
-
Relation of serum homocysteine and lipoprotein(a) concentrations to atherosclerotic disease in a prospective Finnish population based study
-
Alfthan G, Pekkanen J, Jauhiainen M, et al. Relation of serum homocysteine and lipoprotein(a) concentrations to atherosclerotic disease in a prospective Finnish population based study. Atherosclerosis 1994;106:9-19.
-
(1994)
Atherosclerosis
, vol.106
, pp. 9-19
-
-
Alfthan, G.1
Pekkanen, J.2
Jauhiainen, M.3
-
45
-
-
0028132586
-
A prospective study of plasma homocyst(e)ine and risk of ischemic stroke
-
Verhoef P, Hennekens CH, Malinow MR, Kok FJ, Willett WC, Stampfer MJ. A prospective study of plasma homocyst(e)ine and risk of ischemic stroke. Stroke 1994;25:1924-30.
-
(1994)
Stroke
, vol.25
, pp. 1924-1930
-
-
Verhoef, P.1
Hennekens, C.H.2
Malinow, M.R.3
Kok, F.J.4
Willett, W.C.5
Stampfer, M.J.6
-
46
-
-
0026036480
-
The association of elevated plasma homocyst(e)ine with progression of symptomatic peripheral arterial disease
-
Taylor LM Jr, DeFrang RD, Harris EJ Jr, Porter JM. The association of elevated plasma homocyst(e)ine with progression of symptomatic peripheral arterial disease. J Vasc Surg 1991;13:128-36.
-
(1991)
J Vasc Surg
, vol.13
, pp. 128-136
-
-
Taylor Jr., L.M.1
DeFrang, R.D.2
Harris Jr., E.J.3
Porter, J.M.4
-
47
-
-
0028966321
-
Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis
-
Selhub J, Jacques PF, Bostom AG, et al. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995;332:286-91.
-
(1995)
N Engl J Med
, vol.332
, pp. 286-291
-
-
Selhub, J.1
Jacques, P.F.2
Bostom, A.G.3
-
48
-
-
0027523674
-
Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults: The Atherosclerosis Risk in Communities Study
-
Malinow MR, Nieto FJ, Szklo M, Chambless LE, Bond G. Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults: the Atherosclerosis Risk in Communities Study. Circulation 1993;87:1107-13.
-
(1993)
Circulation
, vol.87
, pp. 1107-1113
-
-
Malinow, M.R.1
Nieto, F.J.2
Szklo, M.3
Chambless, L.E.4
Bond, G.5
-
49
-
-
0025886577
-
Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease
-
Genest JJ Jr, McNamara JR, Upson B, et al. Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease. Arterioscler Thromb 1991;11:1129-36.
-
(1991)
Arterioscler Thromb
, vol.11
, pp. 1129-1136
-
-
Genest Jr., J.J.1
McNamara, J.R.2
Upson, B.3
-
51
-
-
0028845307
-
Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men
-
Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995;346:1395-8.
-
(1995)
Lancet
, vol.346
, pp. 1395-1398
-
-
Perry, I.J.1
Refsum, H.2
Morris, R.W.3
Ebrahim, S.B.4
Ueland, P.M.5
Shaper, A.G.6
-
52
-
-
1842331509
-
Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project
-
Graham IM, Daly LE, Refsum HM, et al. Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project. JAMA 1997;277:1775-81.
-
(1997)
JAMA
, vol.277
, pp. 1775-1781
-
-
Graham, I.M.1
Daly, L.E.2
Refsum, H.M.3
-
53
-
-
1842370239
-
Plasma homocysteine levels and mortality in patients with coronary arterv disease
-
Nygård O, Nordrehaug IE, Refsum H, Ueland PM, Farstad M, Vollset SE. Plasma homocysteine levels and mortality in patients with coronary arterv disease. N Engl J Med 1997;337:230-6.
-
(1997)
N Engl J Med
, vol.337
, pp. 230-236
-
-
Nygård, O.1
Nordrehaug, I.E.2
Refsum, H.3
Ueland, P.M.4
Farstad, M.5
Vollset, S.E.6
-
54
-
-
0029066299
-
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: Probable benefits of increasing folk acid intakes
-
Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folk acid intakes. JAMA 1995;274:1049-57.
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
55
-
-
0029921114
-
Hyperhomocysteinemia as a risk factor for deep-vein thrombosis
-
den Heijer M, Kostor T, Blom HJ, et al. Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med 1996;334:759-62.
-
(1996)
N Engl J Med
, vol.334
, pp. 759-762
-
-
Den Heijer, M.1
Kostor, T.2
Blom, H.J.3
-
56
-
-
0030953866
-
Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism
-
Ridker PM, Hennekens CH, Selhub J, Miletich JP, Malinow MR, Stampfer MJ. Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism. Circulation 1997;95:1777-82.
-
(1997)
Circulation
, vol.95
, pp. 1777-1782
-
-
Ridker, P.M.1
Hennekens, C.H.2
Selhub, J.3
Miletich, J.P.4
Malinow, M.R.5
Stampfer, M.J.6
-
58
-
-
0001256866
-
B vitamin supplementation lowers homocysteine levels in heart disease
-
abstract
-
Saltzman E, Mason JB, Jacques PF, et al. B vitamin supplementation lowers homocysteine levels in heart disease. Clin Res 1994;42:172A. abstract.
-
(1994)
Clin Res
, vol.42
-
-
Saltzman, E.1
Mason, J.B.2
Jacques, P.F.3
-
60
-
-
0017197285
-
Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response in its genesis
-
Harker LA, Ross R, Slichter SJ, Scott CR. Homocystine-induced arteriosclerosis: the role of endothelial cell injury and platelet response in its genesis. J Clin Invest 1976;58:731-41.
-
(1976)
J Clin Invest
, vol.58
, pp. 731-741
-
-
Harker, L.A.1
Ross, R.2
Slichter, S.J.3
Scott, C.R.4
-
61
-
-
0025278366
-
The spectrum of diseases of small coronary arteries and their physiologic consequences
-
James TN. The spectrum of diseases of small coronary arteries and their physiologic consequences. J Am Coll Cardiol 1990;15:763-74.
-
(1990)
J Am Coll Cardiol
, vol.15
, pp. 763-774
-
-
James, T.N.1
-
62
-
-
0030015522
-
Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia
-
Lentz SR, Sobey CG, Piegors DJ, et al. Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia. J Clin Invest 1996;98:24-9.
-
(1996)
J Clin Invest
, vol.98
, pp. 24-29
-
-
Lentz, S.R.1
Sobey, C.G.2
Piegors, D.J.3
-
63
-
-
0027255291
-
Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not in their heterozygous parents
-
Celermajer DS, Sorensen K, Ryalls M, et al. Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not in their heterozygous parents. J Am Coll Cardiol 1993;22: 854-8.
-
(1993)
J Am Coll Cardiol
, vol.22
, pp. 854-858
-
-
Celermajer, D.S.1
Sorensen, K.2
Ryalls, M.3
-
64
-
-
0028957460
-
Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease
-
van den Berg M, Boers GH, Franken DG, et al. Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease. Eur J Clin Invest 1995;25:176-81.
-
(1995)
Eur J Clin Invest
, vol.25
, pp. 176-181
-
-
Van Den Berg, M.1
Boers, G.H.2
Franken, D.G.3
-
65
-
-
0023874558
-
Measurement of plasma thiols after derivatization with monobromobimane
-
Velury S, Howell SB. Measurement of plasma thiols after derivatization with monobromobimane. J Chromatogr 1988;424:141-6.
-
(1988)
J Chromatogr
, vol.424
, pp. 141-146
-
-
Velury, S.1
Howell, S.B.2
-
66
-
-
0027531427
-
Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
-
Stamler JS, Osborne JA, Jaraki O, et al. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest 1993;91:308-18.
-
(1993)
J Clin Invest
, vol.91
, pp. 308-318
-
-
Stamler, J.S.1
Osborne, J.A.2
Jaraki, O.3
-
67
-
-
0028921840
-
Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction
-
Andersson A, Lindgren A, Hultberg B. Effect of thiol oxidation and thiol export from erythrocytes on determination of redox status of homocysteine and other thiols in plasma from healthy subjects and patients with cerebral infarction. Clin Chem 1995;41:361-6.
-
(1995)
Clin Chem
, vol.41
, pp. 361-366
-
-
Andersson, A.1
Lindgren, A.2
Hultberg, B.3
-
69
-
-
0018858624
-
Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury
-
Wall RT, Harlan JM, Harker LA, Striker GE. Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury. Thromb Res 1980;18:113-21.
-
(1980)
Thromb Res
, vol.18
, pp. 113-121
-
-
Wall, R.T.1
Harlan, J.M.2
Harker, L.A.3
Striker, G.E.4
-
70
-
-
0020520336
-
Endothelial cell dysfunction in homocystinuria
-
de Groot PG, Willems C, Boers GH, Gonsalves MD, van Aken WG, van Mourik JA. Endothelial cell dysfunction in homocystinuria. Eur J Clin Invest 1983;13:405-10.
-
(1983)
Eur J Clin Invest
, vol.13
, pp. 405-410
-
-
De Groot, P.G.1
Willems, C.2
Boers, G.H.3
Gonsalves, M.D.4
Van Aken, W.G.5
Van Mourik, J.A.6
-
71
-
-
0022552919
-
Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
-
Starkebaum G, Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 1986;77:1370-6.
-
(1986)
J Clin Invest
, vol.77
, pp. 1370-1376
-
-
Starkebaum, G.1
Harlan, J.M.2
-
72
-
-
0015954510
-
Generation of superoxide free radical during the autooxidation of thiols
-
Misra HP. Generation of superoxide free radical during the autooxidation of thiols. J Biol Chem 1974;249:2151-5.
-
(1974)
J Biol Chem
, vol.249
, pp. 2151-2155
-
-
Misra, H.P.1
-
73
-
-
0020477158
-
Superoxide-dependent formation of hydroxyl radicals in the presence of thiol compounds
-
Rowley DA, Halliwell B. Superoxide-dependent formation of hydroxyl radicals in the presence of thiol compounds. FEBS Lett 1982;138:33-6.
-
(1982)
FEBS Lett
, vol.138
, pp. 33-36
-
-
Rowley, D.A.1
Halliwell, B.2
-
74
-
-
0002888991
-
Superoxide-mediated oxidation of low density lipoprotein by thiols
-
Cerutti PA, Fridovich I, McCord JM, eds. New York: Alan R. Liss
-
Heinecke JW. Superoxide-mediated oxidation of low density lipoprotein by thiols. In: Cerutti PA, Fridovich I, McCord JM, eds. Oxy-radicals in molecular biology and pathology. New York: Alan R. Liss, 1988:443-57.
-
(1988)
Oxy-radicals in Molecular Biology and Pathology
, pp. 443-457
-
-
Heinecke, J.W.1
-
75
-
-
0030188563
-
The oxidant stress of hyperhomocyst(e)inemia
-
Loscalzo J. The oxidant stress of hyperhomocyst(e)inemia. J Clin Invest 1996;98:5-7.
-
(1996)
J Clin Invest
, vol.98
, pp. 5-7
-
-
Loscalzo, J.1
-
76
-
-
0023664723
-
The role of sultur-containing amino acids in superoxide production and modification of low-density lipoprotein by arterial smooth muscle cells
-
Heinecke JW, Rosen H, Suzuki LA, Chait A. The role of sultur-containing amino acids in superoxide production and modification of low-density lipoprotein by arterial smooth muscle cells. J Biol Chem 1987;262: 10098-103.
-
(1987)
J Biol Chem
, vol.262
, pp. 10098-10103
-
-
Heinecke, J.W.1
Rosen, H.2
Suzuki, L.A.3
Chait, A.4
-
77
-
-
0014434483
-
Activation of Hageman factor by L-homocystine
-
Ratnoff OD. Activation of Hageman factor by L-homocystine. Science 1968;162:1007-9.
-
(1968)
Science
, vol.162
, pp. 1007-1009
-
-
Ratnoff, O.D.1
-
78
-
-
0022472013
-
Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator
-
Rodgers GM, Kane WH. Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator. J Clin Invest 1986; 77:1909-16.
-
(1986)
J Clin Invest
, vol.77
, pp. 1909-1916
-
-
Rodgers, G.M.1
Kane, W.H.2
-
79
-
-
0025190042
-
Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells
-
Rodgers GM, Conn MT. Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells. Blood 1990;75:895-901.
-
(1990)
Blood
, vol.75
, pp. 895-901
-
-
Rodgers, G.M.1
Conn, M.T.2
-
80
-
-
0026345948
-
Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
-
Lentz SR, Sadler JE. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest 1991;88:1906-14.
-
(1991)
J Clin Invest
, vol.88
, pp. 1906-1914
-
-
Lentz, S.R.1
Sadler, J.E.2
-
81
-
-
0027250615
-
Homocysteine, a risk factor for premature vascular disease and thrombosis induces tissue factor activity in endothelial cells
-
Fryer RH, Wilson BD, Gubler DB, Fitzgerald LA, Rodgers GM. Homocysteine, a risk factor for premature vascular disease and thrombosis induces tissue factor activity in endothelial cells. Arterioscler Thromb 1993; 13:1327-33.
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 1327-1333
-
-
Fryer, R.H.1
Wilson, B.D.2
Gubler, D.B.3
Fitzgerald, L.A.4
Rodgers, G.M.5
-
82
-
-
0027319970
-
Homocysteine, a thrombogenic agent suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells
-
Nishinaga M, Ozawa T, Shimada K. Homocysteine, a thrombogenic agent suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells. J Clin Invest 1993;92:1381-6.
-
(1993)
J Clin Invest
, vol.92
, pp. 1381-1386
-
-
Nishinaga, M.1
Ozawa, T.2
Shimada, K.3
-
83
-
-
0026586147
-
S-nitrosylation of proteins with nitric oxide: Synthesis and characterization of biologically active compounds
-
Stamler JS, Simon DI, Osborne JA, et al. S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. Proc Natl Acad Sci U S A 1992;89:444-8.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 444-448
-
-
Stamler, J.S.1
Simon, D.I.2
Osborne, J.A.3
-
84
-
-
0026570225
-
Inactivation of endothelial derived relaxing factor by oxidized lipoproteins
-
Chin JH, Azhar S, Hoffman BB. Inactivation of endothelial derived relaxing factor by oxidized lipoproteins. J Clin Invest 1992;89:10-8.
-
(1992)
J Clin Invest
, vol.89
, pp. 10-18
-
-
Chin, J.H.1
Azhar, S.2
Hoffman, B.B.3
-
85
-
-
0028821643
-
Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase
-
Liao JK, Shin WS, Lee WY, Clark SL. Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 1995;270:319-24.
-
(1995)
J Biol Chem
, vol.270
, pp. 319-324
-
-
Liao, J.K.1
Shin, W.S.2
Lee, W.Y.3
Clark, S.L.4
-
86
-
-
0028948446
-
Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia
-
Blom HJ, Kleinveld HA, Boers GH, et al. Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia. Eur J Clin Invest 1995;25:149-54.
-
(1995)
Eur J Clin Invest
, vol.25
, pp. 149-154
-
-
Blom, H.J.1
Kleinveld, H.A.2
Boers, G.H.3
-
87
-
-
1842411860
-
Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxjdase
-
Upchurch GR Jr, Welch GN, Fabian AJ, et al. Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxjdase J Biol Chem 1997;272:17012-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 17012-17017
-
-
Upchurch Jr., G.R.1
Welch, G.N.2
Fabian, A.J.3
-
88
-
-
0021041780
-
Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons
-
Harker LA, Harlan JM, Ross R. Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons. Circ Res 1983;53:731-9.
-
(1983)
Circ Res
, vol.53
, pp. 731-739
-
-
Harker, L.A.1
Harlan, J.M.2
Ross, R.3
-
89
-
-
0028298171
-
Promotion of vascular smooth muscle cell growth by homocysteine: A link to atherosclerosis
-
Tsai J-C, Perrella MA, Yoshizumi M, et al. Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci U S A 1994;91:6369-73.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 6369-6373
-
-
Tsai, J.-C.1
Perrella, M.A.2
Yoshizumi, M.3
-
90
-
-
13344270367
-
Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells
-
Tsai JC, Wang H, Perrella MA, et al. Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells. J Clin Invest 1996;97:146-53.
-
(1996)
J Clin Invest
, vol.97
, pp. 146-153
-
-
Tsai, J.C.1
Wang, H.2
Perrella, M.A.3
-
91
-
-
0031965641
-
Homocysteine-induced nitric oxide production in vascular smooth muscle cells by NF-κB dependent transcriptional activation of Nos2
-
Welch GN, Upchurch GR Jr, Farivar RS, et al. Homocysteine-induced nitric oxide production in vascular smooth muscle cells by NF-κB dependent transcriptional activation of Nos2. Proc Am Assoc Phys 1998;110:22-31.
-
(1998)
Proc Am Assoc Phys
, vol.110
, pp. 22-31
-
-
Welch, G.N.1
Upchurch Jr., G.R.2
Farivar, R.S.3
-
92
-
-
0028970479
-
Expression of a constitutive NF-kappa B-like activity is essential for proliferation of cultured bovine vascular smooth muscle cells
-
Bellas RE, Lee JS, Sonenshein GE. Expression of a constitutive NF-kappa B-like activity is essential for proliferation of cultured bovine vascular smooth muscle cells. J Clin Invest 1995;96:2521-7.
-
(1995)
J Clin Invest
, vol.96
, pp. 2521-2527
-
-
Bellas, R.E.1
Lee, J.S.2
Sonenshein, G.E.3
-
93
-
-
0002336573
-
Thiolation of low-density lipoprotein by homocysteine thiolactone causes increased aggregation and altered interaction with cultured macrophages
-
Naruszewicz M, Mirkiewicz E, Olszewski AJ, et al. Thiolation of low-density lipoprotein by homocysteine thiolactone causes increased aggregation and altered interaction with cultured macrophages. Nutr Metab Cardiovasc Dis 1994;4:70-77.
-
(1994)
Nutr Metab Cardiovasc Dis
, vol.4
, pp. 70-77
-
-
Naruszewicz, M.1
Mirkiewicz, E.2
Olszewski, A.J.3
-
94
-
-
0031035742
-
Metabolism of homocysteine thiolactone in human cell cultures: Possible mechanism for pathological consequences of elevated homocysteine levels
-
Jakubowski H. Metabolism of homocysteine thiolactone in human cell cultures: possible mechanism for pathological consequences of elevated homocysteine levels. J Biol Chem 1997;272:1935-42.
-
(1997)
J Biol Chem
, vol.272
, pp. 1935-1942
-
-
Jakubowski, H.1
-
95
-
-
0027493344
-
Chemical pathology of homocysteine. I. Atherogenesis
-
McCully KS. Chemical pathology of homocysteine. I. Atherogenesis. Ann Clin Lab Sci 1993;23:477-93.
-
(1993)
Ann Clin Lab Sci
, vol.23
, pp. 477-493
-
-
McCully, K.S.1
-
96
-
-
0028069519
-
Chemical pathology of homocysteine. II. Carcinogenesis and homocysteine thiolactone metabolism
-
Idem. Chemical pathology of homocysteine. II. Carcinogenesis and homocysteine thiolactone metabolism. Ann Clin Lab Sci 1994;24:27-59.
-
(1994)
Ann Clin Lab Sci
, vol.24
, pp. 27-59
-
-
McCully, K.S.1
-
97
-
-
0028007948
-
Chemical pathology of homocysteine. III. Cellular function and aging
-
Idem. Chemical pathology of homocysteine. III. Cellular function and aging. Ann Clin Lab Sci 1994;24:134-52.
-
(1994)
Ann Clin Lab Sci
, vol.24
, pp. 134-152
-
-
McCully, K.S.1
-
98
-
-
0015219649
-
Homocysteine metabolism in scurvy, growth and arteriosclerosis
-
Idem. Homocysteine metabolism in scurvy, growth and arteriosclerosis. Nature 1971;231:391-2.
-
(1971)
Nature
, vol.231
, pp. 391-392
-
-
McCully, K.S.1
-
99
-
-
0020616462
-
Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid
-
Morel DW, Hessler JR, Chisolm GM. Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid. J Lipid Res 1983;24: 1070-6.
-
(1983)
J Lipid Res
, vol.24
, pp. 1070-1076
-
-
Morel, D.W.1
Hessler, J.R.2
Chisolm, G.M.3
-
100
-
-
0028227192
-
Cytotoxicity of oxidized LDL to porcine aortic smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol
-
Hughes H, Mathews B, Lenz ML, Guyton JR. Cytotoxicity of oxidized LDL to porcine aortic smooth muscle cells is associated with the oxysterols 7-ketocholesterol and 7-hydroxycholesterol. Artenoscler Thromb 1994;14:1177-85.
-
(1994)
Artenoscler Thromb
, vol.14
, pp. 1177-1185
-
-
Hughes, H.1
Mathews, B.2
Lenz, M.L.3
Guyton, J.R.4
-
101
-
-
0027142389
-
Oxidation of low density lipoprotein by thiols: Superoxide-dependent and -independent mechanisms
-
Heinecke JW, Kawamura M, Suzuki L, Chait A. Oxidation of low density lipoprotein by thiols: superoxide-dependent and -independent mechanisms. J Lipid Res 1993;34:2051-61.
-
(1993)
J Lipid Res
, vol.34
, pp. 2051-2061
-
-
Heinecke, J.W.1
Kawamura, M.2
Suzuki, L.3
Chait, A.4
-
102
-
-
0023094333
-
Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor
-
Parthasarathy S. Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor. Biochim Biophys Acta 1987;917:337-40.
-
(1987)
Biochim Biophys Acta
, vol.917
, pp. 337-340
-
-
Parthasarathy, S.1
|