-
1
-
-
0026518215
-
Tackling a weighty problem
-
Friedman, J. M. and Leibel, R. L.. (1992) Tackling a weighty problem. Cell 69, 217-220.
-
(1992)
Cell
, vol.69
, pp. 217-220
-
-
Friedman, J.M.1
Leibel, R.L.2
-
2
-
-
0025733384
-
Animal models of obesity: Genetic aspects
-
Johnson, P. R., Greenwood, M. R., Horwitz, B. A., and Stern, J. S. (1991) Animal models of obesity: Genetic aspects. Ann. Rev. Nutrition 11, 325-353.
-
(1991)
Ann. Rev. Nutrition
, vol.11
, pp. 325-353
-
-
Johnson, P.R.1
Greenwood, M.R.2
Horwitz, B.A.3
Stern, J.S.4
-
3
-
-
0021715985
-
The development of obesity in animals: The role of genetic susceptibility
-
Trayhurn, P. (1984) The development of obesity in animals: The role of genetic susceptibility. Clin. Endocrinol. Metab. 13, 451-474.
-
(1984)
Clin. Endocrinol. Metab.
, vol.13
, pp. 451-474
-
-
Trayhurn, P.1
-
4
-
-
0014004384
-
Diabetes, a new mutation in the mouse
-
Hummel, K. P., Dickie, M. M., and Coleman, D. L. (1966) Diabetes, a new mutation in the mouse. Science 153, 1127-1128.
-
(1966)
Science
, vol.153
, pp. 1127-1128
-
-
Hummel, K.P.1
Dickie, M.M.2
Coleman, D.L.3
-
5
-
-
0000736325
-
Obese, new mutation in house mouse
-
Ingalls, A. M., Dickie, M. M., and Snell, G. D. (1950) Obese, new mutation in house mouse. J. Heredity 41, 317-318.
-
(1950)
J. Heredity
, vol.41
, pp. 317-318
-
-
Ingalls, A.M.1
Dickie, M.M.2
Snell, G.D.3
-
6
-
-
0021705710
-
Animal models of obesity: Classification and characterization
-
Sclafani, A. (1984) Animal models of obesity: Classification and characterization. International J. Obesity 8, 491-508.
-
(1984)
International J. Obesity
, vol.8
, pp. 491-508
-
-
Sclafani, A.1
-
7
-
-
0015792424
-
Effects of parabiosis of obese with diabetes and normal mice
-
Coleman, D. L. (1973) Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 9, 294-298.
-
(1973)
Diabetologia
, vol.9
, pp. 294-298
-
-
Coleman, D.L.1
-
8
-
-
0018139377
-
Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
-
Coleman, D. L. (1978) Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14, 141-148.
-
(1978)
Diabetologia
, vol.14
, pp. 141-148
-
-
Coleman, D.L.1
-
9
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
10
-
-
0028863211
-
Structural organization and chromosomal assignment of the human obese gene
-
Isse, N., Ogawa, Y., Tamura, N., Masuzaki, H., Mori, K., Okazaki, T., Satoh, N., Shigemoto, M., Yoshimasa, Y., Nishi, S., et al. (1995) Structural organization and chromosomal assignment of the human obese gene. J. Biol. Chem. 270, 27,728-27,733.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27728-27733
-
-
Isse, N.1
Ogawa, Y.2
Tamura, N.3
Masuzaki, H.4
Mori, K.5
Okazaki, T.6
Satoh, N.7
Shigemoto, M.8
Yoshimasa, Y.9
Nishi, S.10
-
11
-
-
0029089898
-
The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7
-
Green, E. D., Maffei, M., Braden, V. V., Proenca, R., DeSilva, U., Zhang, Y., Chua, S. Jr., Leibel, R. L., Weissenbach, J., and Friedman, J. M. (1995) The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7. Genome Res. 5, 5-12.
-
(1995)
Genome Res.
, vol.5
, pp. 5-12
-
-
Green, E.D.1
Maffei, M.2
Braden, V.V.3
Proenca, R.4
DeSilva, U.5
Zhang, Y.6
Chua S., Jr.7
Leibel, R.L.8
Weissenbach, J.9
Friedman, J.M.10
-
12
-
-
0028849084
-
The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha
-
He, Y., Chen, H., Quon, M. J., and Reitman, M. (1995) The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha. J. Biol. Chem. 270, 28,887-28,891.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28887-28891
-
-
He, Y.1
Chen, H.2
Quon, M.J.3
Reitman, M.4
-
13
-
-
0030032754
-
Genomic structure and promoter analysis of the human obese gene
-
Gong, D. W., Bi, S., Pratley, R. E., and Weintraub, B. D. (1996) Genomic structure and promoter analysis of the human obese gene. J. Biol. Chem. 271, 3971-3974.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3971-3974
-
-
Gong, D.W.1
Bi, S.2
Pratley, R.E.3
Weintraub, B.D.4
-
14
-
-
0029020677
-
Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity
-
Considine, R. V., Considine, E. L., Williams, C. J., Nyce, M. R., Magosin, S. A., Bauer, T. L., Rosato, E. L., Colberg, J., and Caro, J. F. (1995) Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity J. Clin. Invest. 95, 2986-2988.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2986-2988
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Nyce, M.R.4
Magosin, S.A.5
Bauer, T.L.6
Rosato, E.L.7
Colberg, J.8
Caro, J.F.9
-
15
-
-
0030063976
-
Expression of ob gene in adipose cells. Regulation by insulin
-
Leroy, P., Dessolin, S., Villageois, P., Moon, B. C., Friedman, J. M., Ailhaud, G., and Dani, C., (1996) Expression of ob gene in adipose cells. Regulation by insulin. J. Biol. Chem. 271, 2365-2368.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2365-2368
-
-
Leroy, P.1
Dessolin, S.2
Villageois, P.3
Moon, B.C.4
Friedman, J.M.5
Ailhaud, G.6
Dani, C.7
-
16
-
-
0030460618
-
Leptin: Genes, concepts and clinical perspective
-
Considine, R. V. and Caro, J. F. (1996) Leptin: Genes, concepts and clinical perspective. Hormone Res. 46, 249-256.
-
(1996)
Hormone Res.
, vol.46
, pp. 249-256
-
-
Considine, R.V.1
Caro, J.F.2
-
17
-
-
0029078449
-
Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-LI adipocytes
-
MacDougald, O. A., Hwang, C. S., Fan, H., and Lane, M. D. (1995) Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-LI adipocytes. Proc. Natl. Acad. Sci. USA 92, 9034-9037.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9034-9037
-
-
MacDougald, O.A.1
Hwang, C.S.2
Fan, H.3
Lane, M.D.4
-
18
-
-
0345335191
-
Indication for linkage of the human OB gene region with extreme obesity
-
Clement, K., Garner, C., Hager, J., Philippi, A., LeDue, C., Carey, A., Harris, T. J., Jury, C., Cardon, L. R., Basdevant, A., Demenais, F., Guy-Grand, B., North, M., and Froguel, P. (1996) Indication for linkage of the human OB gene region with extreme obesity. Diabetes 45, 687-690.
-
(1996)
Diabetes
, vol.45
, pp. 687-690
-
-
Clement, K.1
Garner, C.2
Hager, J.3
Philippi, A.4
LeDue, C.5
Carey, A.6
Harris, T.J.7
Jury, C.8
Cardon, L.R.9
Basdevant, A.10
Demenais, F.11
Guy-Grand, B.12
North, M.13
Froguel, P.14
-
19
-
-
0029938057
-
Extreme obesity may be linked to markers flanking the human OB gene
-
Reed, D. R., Ding, Y., Xu, W., Cather, C., Green, E. D., and Price, R. A. (1996) Extreme obesity may be linked to markers flanking the human OB gene. Diabetes 45, 691-694.
-
(1996)
Diabetes
, vol.45
, pp. 691-694
-
-
Reed, D.R.1
Ding, Y.2
Xu, W.3
Cather, C.4
Green, E.D.5
Price, R.A.6
-
20
-
-
0032014836
-
A leptin missense mutation associated with hypogonadism and morbid obesity
-
Strobel, A., Issad, T., Camoin, L., Ozata, M., and Strosberg, A. D. (1998) A leptin missense mutation associated with hypogonadism and morbid obesity. Nature Genet. 18, 213-215.
-
(1998)
Nature Genet.
, vol.18
, pp. 213-215
-
-
Strobel, A.1
Issad, T.2
Camoin, L.3
Ozata, M.4
Strosberg, A.D.5
-
21
-
-
0029893230
-
Mutation screening and identification of a sequence variation in the human ob gene coding region
-
Considine, R. V., Considine, E. L., Williams, C. J., Nyce, M. R., Zhang, P., Opentanova, I., Ohannesian, J. P., Kolaczynski, J. W., Bauer, T. L., Moore, J. H., and Caro, J. F. (1996) Mutation screening and identification of a sequence variation in the human ob gene coding region. Biochem. Biophys. Res. Comm. 220, 735-739.
-
(1996)
Biochem. Biophys. Res. Comm.
, vol.220
, pp. 735-739
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Nyce, M.R.4
Zhang, P.5
Opentanova, I.6
Ohannesian, J.P.7
Kolaczynski, J.W.8
Bauer, T.L.9
Moore, J.H.10
Caro, J.F.11
-
22
-
-
15844399534
-
Human obese gene: Molecular screening in Japanese and Asian Indian NIDDM patients associated with obesity
-
Niki, T., Mori, H., Tamori, Y., Kishimoto-Hashirmoto, M., Ueno, H., Araki, S., Masugi, J., Sawant, N., Majithia, H. R., Rais, N., et al. (1996) Human obese gene: Molecular screening in Japanese and Asian Indian NIDDM patients associated with obesity. Diabetes 45, 675-678.
-
(1996)
Diabetes
, vol.45
, pp. 675-678
-
-
Niki, T.1
Mori, H.2
Tamori, Y.3
Kishimoto-Hashirmoto, M.4
Ueno, H.5
Araki, S.6
Masugi, J.7
Sawant, N.8
Majithia, H.R.9
Rais, N.10
-
23
-
-
15844373886
-
Absence of mutations in the human OB gene in obese/diabetic subjects
-
Maffei, M., Stoffel, M., Barone, M., Moon, B., Dammerman, M., Ravussin, E., Bogardus, C., Ludwig, D. S., Flier, J. S., Talley, M., et al. (1996) Absence of mutations in the human OB gene in obese/diabetic subjects. Diabetes 45, 679-682.
-
(1996)
Diabetes
, vol.45
, pp. 679-682
-
-
Maffei, M.1
Stoffel, M.2
Barone, M.3
Moon, B.4
Dammerman, M.5
Ravussin, E.6
Bogardus, C.7
Ludwig, D.S.8
Flier, J.S.9
Talley, M.10
-
24
-
-
0029086473
-
Threading analysis suggests that the obese gene product may be a helical cytokine
-
Madej, T., Boguski, M. S., and Bryant, B. H. (1995) Threading analysis suggests that the obese gene product may be a helical cytokine. Febs Letts. 373, 13-18.
-
(1995)
Febs Letts.
, vol.373
, pp. 13-18
-
-
Madej, T.1
Boguski, M.S.2
Bryant, B.H.3
-
25
-
-
0031589139
-
Leptin is a four-helix bundle: Secondary structure by NMR
-
Klinc, A. D., Becker, G. W., Churgay, L. M., Landen, B. E., Martin, D. K., Muth, W. L., Rathnachalam, R., Richardson, J. M., Schoner, B., Ulmer, M., and Hale, J. E. (1997) Leptin is a four-helix bundle: Secondary structure by NMR. Febs Letts. 407, 239-242.
-
(1997)
Febs Letts.
, vol.407
, pp. 239-242
-
-
Klinc, A.D.1
Becker, G.W.2
Churgay, L.M.3
Landen, B.E.4
Martin, D.K.5
Muth, W.L.6
Rathnachalam, R.7
Richardson, J.M.8
Schoner, B.9
Ulmer, M.10
Hale, J.E.11
-
26
-
-
0030977992
-
Crystal structure of the obese protein leptin-E100
-
Zhang, F., Basinski, M. B., Beals, J. M., Briggs, S. L., Churgay, L. M., Clawson, D. K., DiMarchi, R. D., Furman, T. C., Hale, J. E., Hsiung, H. M., Schoner, B. E., Smith, D. P., Zhang, X. Y., Wery, J. P., and Schevitz, R. W. (1997) Crystal structure of the obese protein leptin-E100. Nature 387, 206-209.
-
(1997)
Nature
, vol.387
, pp. 206-209
-
-
Zhang, F.1
Basinski, M.B.2
Beals, J.M.3
Briggs, S.L.4
Churgay, L.M.5
Clawson, D.K.6
DiMarchi, R.D.7
Furman, T.C.8
Hale, J.E.9
Hsiung, H.M.10
Schoner, B.E.11
Smith, D.P.12
Zhang, X.Y.13
Wery, J.P.14
Schevitz, R.W.15
-
27
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia, L. A., Dembski, M., Weng, X., Deng, N., Culpepper, J., Devos, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., et al. (1995) Identification and expression cloning of a leptin receptor, OB-R. Cell 83, 1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
-
28
-
-
0029980118
-
OB protein binds specifically to the choroid plexus of mice and rats
-
Devos, R., Richards, J. G., Campfield, L. A., Tartaglia, L. A., Guisez, Y., van der Heyden, J., Travernier, J., Plactinck, G., and Burn, P. (1996) OB protein binds specifically to the choroid plexus of mice and rats. Pro. Natl. Acad. Sci. USA 93, 5668-5673.
-
(1996)
Pro. Natl. Acad. Sci. USA
, vol.93
, pp. 5668-5673
-
-
Devos, R.1
Richards, J.G.2
Campfield, L.A.3
Tartaglia, L.A.4
Guisez, Y.5
Van der Heyden, J.6
Travernier, J.7
Plactinck, G.8
Burn, P.9
-
29
-
-
0030006511
-
Mapping of the OB receptor to Ip in a region of nonconserved gene order from mouse and rat to human
-
Chung, W. K., Power-Kehoc, L., Chua, M., and Leibel, R. L. (1996) Mapping of the OB receptor to Ip in a region of nonconserved gene order from mouse and rat to human. Genome Res. 6, 431-438.
-
(1996)
Genome Res.
, vol.6
, pp. 431-438
-
-
Chung, W.K.1
Power-Kehoc, L.2
Chua, M.3
Leibel, R.L.4
-
30
-
-
0024393839
-
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
-
Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Yasukawa, K., Matsuda, T., Hirano, T., and Kishimoto, T. (1989) Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell 58, 573-581.
-
(1989)
Cell
, vol.58
, pp. 573-581
-
-
Taga, T.1
Hibi, M.2
Hirata, Y.3
Yamasaki, K.4
Yasukawa, K.5
Matsuda, T.6
Hirano, T.7
Kishimoto, T.8
-
31
-
-
0025604307
-
Expression cloning of a human granulocyte colony-stimulating factor receptor: A structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains
-
Larsen, A., Davis, T., Curtis, B. M., Gimpel, S., Sims, J. E., Cosman, D., Park, L., Sorensen, E., March, C. J., and Smith, C.A. (1990) Expression cloning of a human granulocyte colony-stimulating factor receptor: A structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains. J. Exp. Med. 172, 1559-1570.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1559-1570
-
-
Larsen, A.1
Davis, T.2
Curtis, B.M.3
Gimpel, S.4
Sims, J.E.5
Cosman, D.6
Park, L.7
Sorensen, E.8
March, C.J.9
Smith, C.A.10
-
32
-
-
0025835275
-
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130
-
Gearing, D. P., Thut, C. J., VandeBos, T., Gimpel, S. D., Delaney, P. B., King, J., Price, V., Cosman, D., and Beckmann, M. P. (1991) Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. Embo J. 10, 2839-2848.
-
(1991)
Embo J.
, vol.10
, pp. 2839-2848
-
-
Gearing, D.P.1
Thut, C.J.2
VandeBos, T.3
Gimpel, S.D.4
Delaney, P.B.5
King, J.6
Price, V.7
Cosman, D.8
Beckmann, M.P.9
-
33
-
-
0002843205
-
An introduction to cytokine receptors
-
Nicola, N. A., ed. 1994 Sambrook and Tooze, Oxford, UK. Oxford University Press
-
Hilton, D. J. (1994) An introduction to cytokine receptors, in Guidebook to Cytokines and Their Receptors. Nicola, N. A., ed. 1994 Sambrook and Tooze, Oxford, UK. Oxford University Press, pp. 8-16.
-
(1994)
Guidebook to Cytokines and Their Receptors
, pp. 8-16
-
-
Hilton, D.J.1
-
34
-
-
0030007116
-
Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction
-
Cioffi, J. A., Shafer, A. W., Zupancic, T. J., Smith-Gbur, J., Mikhail, A., Platika, D., and Snodgrass, H. R. (1996) Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction. Nature Med. 2, 585-589.
-
(1996)
Nature Med.
, vol.2
, pp. 585-589
-
-
Cioffi, J.A.1
Shafer, A.W.2
Zupancic, T.J.3
Smith-Gbur, J.4
Mikhail, A.5
Platika, D.6
Snodgrass, H.R.7
-
35
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee, G. H., Proenca, R., Montez, J. M., Carroll, K. M., Darvishzadeh, J. G., Lee, J. I., and Friedman, J. M. (1996) Abnormal splicing of the leptin receptor in diabetic mice. Nature 379, 632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
36
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen, H., Charlat, O., Tartaglia, L. A., Woolf, E. A., Weng, X., Ellis, S. J., Lakey, N. D., Culpepper, J., Moore, K. J., Breitbart, R. E., Duyk, G. M., Tepper, R. I., and Morgenstern, J. P. (1996) Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice. Cell 84, 491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
37
-
-
0030434655
-
Leptin and OB-R: Body weight regulation by a cytokine receptor
-
White, D. W. and Tartaglia, L. A. (1996) Leptin and OB-R: Body weight regulation by a cytokine receptor. Cytokine Growth Factor Rev. 7, 303-309.
-
(1996)
Cytokine Growth Factor Rev.
, vol.7
, pp. 303-309
-
-
White, D.W.1
Tartaglia, L.A.2
-
38
-
-
0031436148
-
Divergent signaling capacities of the long and short isoforms of the leptin receptor
-
Bjorbaek, C., Uotani, S., Dasilva, B., and Flier, J. S. (1997) Divergent signaling capacities of the long and short isoforms of the leptin receptor. J. Biol. Chem. 272, 32,686-32,695.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32686-32695
-
-
Bjorbaek, C.1
Uotani, S.2
Dasilva, B.3
Flier, J.S.4
-
39
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in diabetic mice
-
Ghilardi, N., Ziegler, S., Wiestner, A., Stoffel, R., Heim, M. H., and Skoda, R. C. (1996) Defective STAT signaling by the leptin receptor in diabetic mice. Pro. Natl. Acad. Sci. USA 93, 6231-6235.
-
(1996)
Pro. Natl. Acad. Sci. USA
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
Stoffel, R.4
Heim, M.H.5
Skoda, R.C.6
-
40
-
-
0029895233
-
Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
-
Mercer, J. G., Hoggard, N., Williams, L. M., Lawrence, C. B., Hannah, L. T., and Trayhurn, P. (1996) Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. Febs Lett. 387, 113-116.
-
(1996)
Febs Lett.
, vol.387
, pp. 113-116
-
-
Mercer, J.G.1
Hoggard, N.2
Williams, L.M.3
Lawrence, C.B.4
Hannah, L.T.5
Trayhurn, P.6
-
41
-
-
0030594830
-
Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
-
Caro, J. F., Kolaczynski, J. W., Nyce, M. R., Ohannesian, J. P., Opentanova, I., Goldman, W. H., Lynn, R. B., Zhang, P. L., Sinha, M. K., and Considine, R. V. (1996) Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance Lancet 348, 159-161.
-
(1996)
Lancet
, vol.348
, pp. 159-161
-
-
Caro, J.F.1
Kolaczynski, J.W.2
Nyce, M.R.3
Ohannesian, J.P.4
Opentanova, I.5
Goldman, W.H.6
Lynn, R.B.7
Zhang, P.L.8
Sinha, M.K.9
Considine, R.V.10
-
42
-
-
0029864416
-
Leptin enters the brain by a saturable system independent of insulin
-
Banks, W. A., Kastin, A. J., Huang, W., Jaspan, J. B., and Maness, L. M. (1996) Leptin enters the brain by a saturable system independent of insulin. Peptides 17, 305-311.
-
(1996)
Peptides
, vol.17
, pp. 305-311
-
-
Banks, W.A.1
Kastin, A.J.2
Huang, W.3
Jaspan, J.B.4
Maness, L.M.5
-
43
-
-
0030942844
-
The leptin receptor
-
Tartaglia, L. A. (1997) The leptin receptor. J. Biol. Chem. 272, 6093-6096.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
45
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
-
Chua, S., Jr., Chung, W. K., Wu-Peng, X. S., Zhang, Y., Liu, S. M., Tartaglia, L., and Leibel, R. L. (1996) Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 271, 994-996.
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua S., Jr.1
Chung, W.K.2
Wu-Peng, X.S.3
Zhang, Y.4
Liu, S.M.5
Tartaglia, L.6
Leibel, R.L.7
-
46
-
-
0030137757
-
Leptin receptor missense mutation in the fatty Zucker rat
-
Phillips, M. S., Liu, Q., Hammond, H. A., Dugan, V., Hey, P. J., Caskey, C. J., and Hess, J. F. (1996) Leptin receptor missense mutation in the fatty Zucker rat. Nature Genet. 13, 18-19.
-
(1996)
Nature Genet.
, vol.13
, pp. 18-19
-
-
Phillips, M.S.1
Liu, Q.2
Hammond, H.A.3
Dugan, V.4
Hey, P.J.5
Caskey, C.J.6
Hess, J.F.7
-
47
-
-
9344241376
-
Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr)
-
Chua, S., Jr., White, D. W., Wu-Peng, X. S., Liu, S. M., Okada, N., Kershaw, E. E., Chung, W. K., Power-Kehoe, L., Chua, M., Tartaglia, L. A., and Leibel, R. L. (1996) Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr). Diabetes 45, 1141-1143.
-
(1996)
Diabetes
, vol.45
, pp. 1141-1143
-
-
Chua S., Jr.1
White, D.W.2
Wu-Peng, X.S.3
Liu, S.M.4
Okada, N.5
Kershaw, E.E.6
Chung, W.K.7
Power-Kehoe, L.8
Chua, M.9
Tartaglia, L.A.10
Leibel, R.L.11
-
48
-
-
0030267744
-
Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat
-
Takaya, K., Ogawa, Y., Hiraoka, J., Hosoda, K., Yamori, Y., Nakao, K., and Koletsky, R. J. (1996) Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat. Nature Genet. 14, 130-131.
-
(1996)
Nature Genet.
, vol.14
, pp. 130-131
-
-
Takaya, K.1
Ogawa, Y.2
Hiraoka, J.3
Hosoda, K.4
Yamori, Y.5
Nakao, K.6
Koletsky, R.J.7
-
49
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
Clement, K., Vaisse, C., Lahlou, N., Cabrol, S., Pelloux, V., Cassuto, D., Gourmelen, M., Dina, C., Chambaz, J., Lacorte, J. M., Basdevant, A., Bougneres, P., Lebouc, Y., Froguel, P., and Guygrand, B. (1998) A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 392, 398-401.
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clement, K.1
Vaisse, C.2
Lahlou, N.3
Cabrol, S.4
Pelloux, V.5
Cassuto, D.6
Gourmelen, M.7
Dina, C.8
Chambaz, J.9
Lacorte, J.M.10
Basdevant, A.11
Bougneres, P.12
Lebouc, Y.13
Froguel, P.14
Guygrand, B.15
-
50
-
-
0029050937
-
Overexpression of the obese (ob) gene in adipose tissue of human obese subjects
-
Lonnqvist, F., Arner, P., Nordfors, L., and Schalling, M. (1995) Overexpression of the obese (ob) gene in adipose tissue of human obese subjects. Nature Med. 1, 950-953.
-
(1995)
Nature Med.
, vol.1
, pp. 950-953
-
-
Lonnqvist, F.1
Arner, P.2
Nordfors, L.3
Schalling, M.4
-
51
-
-
0029083859
-
Increased obese mRNA expression in omental fat cells from massively obese humans
-
Hamilton, B. S., Paglia, D., Kwan, A. Y., and Deitel, M. (1995) Increased obese mRNA expression in omental fat cells from massively obese humans. Nature Med. 1, 953-956.
-
(1995)
Nature Med.
, vol.1
, pp. 953-956
-
-
Hamilton, B.S.1
Paglia, D.2
Kwan, A.Y.3
Deitel, M.4
-
52
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., McKee, L. J., Bauer, T. L., et al. (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New Eng. J. Med. 334, 292-295.
-
(1996)
New Eng. J. Med.
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
McKee, L.J.9
Bauer, T.L.10
-
53
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., Fei, H., Kim, S, Lallone, R., Ranganathan, S., et al. (1995) Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Med. 1, 1155-1161.
-
(1995)
Nature Med.
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
-
54
-
-
0029033031
-
Cloning of rat obese cDNA and its expression in obese rats
-
Murakami, T. and Shima, K. (1995) Cloning of rat obese cDNA and its expression in obese rats. Biochem. Biophys. Res. Comm. 209, 944-952.
-
(1995)
Biochem. Biophys. Res. Comm.
, vol.209
, pp. 944-952
-
-
Murakami, T.1
Shima, K.2
-
55
-
-
0029086176
-
Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats
-
Ogawa, Y., Masuzaki, H., Isse, N., Okazaki, T., Mori, K., Shigemoto, M., Satoh, N., Tamura, N., Hosoda, K., Yoshimasa, Y., et al. (1995) Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats. J. Clin. Invest. 96, 1647-1652.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1647-1652
-
-
Ogawa, Y.1
Masuzaki, H.2
Isse, N.3
Okazaki, T.4
Mori, K.5
Shigemoto, M.6
Satoh, N.7
Tamura, N.8
Hosoda, K.9
Yoshimasa, Y.10
-
56
-
-
0029131574
-
Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity
-
Frederich, R. C., B. Lollmann, A. Hamann, A. Napolitano-Rosen, B. B. Kahn, B. B. Lowell and J. S. Flier. (1995) Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. J. Clin. Invest. 96, 1658-1663.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1658-1663
-
-
Frederich, R.C.1
Lollmann, B.2
Hamann, A.3
Napolitano-Rosen, A.4
Kahn, B.B.5
Lowell, B.B.6
Flier, J.S.7
-
57
-
-
0029043638
-
Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned rats
-
Funahashi, T., Shimomura, I., Hiraoka, H., Arai, T., Takahashi, M., Nakamura, T., Nozaki, S., Yamashita, S., Takemura, K., Tokunaga, K., et al. (1995) Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned rats. Biochem. Biophys. Res. Comm. 211, 469-475.
-
(1995)
Biochem. Biophys. Res. Comm.
, vol.211
, pp. 469-475
-
-
Funahashi, T.1
Shimomura, I.2
Hiraoka, H.3
Arai, T.4
Takahashi, M.5
Nakamura, T.6
Nozaki, S.7
Yamashita, S.8
Takemura, K.9
Tokunaga, K.10
-
58
-
-
0029118124
-
Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus
-
Maffei, M., Fei, H., Lee, G. H., Dani, C., Leroy, P., Zhang, Y., Proenca, R., Negrel, R., Ailhaud, G., and Friedman, J. M. (1995) Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Pro. Natl. Acad. Sci. USA 92, 6957-6960.
-
(1995)
Pro. Natl. Acad. Sci. USA
, vol.92
, pp. 6957-6960
-
-
Maffei, M.1
Fei, H.2
Lee, G.H.3
Dani, C.4
Leroy, P.5
Zhang, Y.6
Proenca, R.7
Negrel, R.8
Ailhaud, G.9
Friedman, J.M.10
-
59
-
-
17444442925
-
Augmented expression of obese (ob) gene during the process of obesity in genetically obese-hyperglycemic Wistar fatty (fa/fa) rats
-
Masuzaki, H., Hosoda, K., Ogawa, Y., Shigemoto, M., Satoh, N., Mori, K., Tamura, N., Nishi, S., Yoshimasa, Y., Yamori, Y., and Nakao, K. (1996) Augmented expression of obese (ob) gene during the process of obesity in genetically obese-hyperglycemic Wistar fatty (fa/fa) rats. Febs Letts. 378, 267-271.
-
(1996)
Febs Letts.
, vol.378
, pp. 267-271
-
-
Masuzaki, H.1
Hosoda, K.2
Ogawa, Y.3
Shigemoto, M.4
Satoh, N.5
Mori, K.6
Tamura, N.7
Nishi, S.8
Yoshimasa, Y.9
Yamori, Y.10
Nakao, K.11
-
60
-
-
0028793697
-
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
-
Frederich, R. C., Hamann, A., Anderson, S., Lollmann, B., Lowell, B. B., and Flier, J. S., (1995) Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action. Nature Med. 1, 1311-1314.
-
(1995)
Nature Med.
, vol.1
, pp. 1311-1314
-
-
Frederich, R.C.1
Hamann, A.2
Anderson, S.3
Lollmann, B.4
Lowell, B.B.5
Flier, J.S.6
-
61
-
-
0029942497
-
Pharmacologic manipulation of ob expression in a dietary model of obesity
-
Collins, S. and Surwit, R. S. (1996) Pharmacologic manipulation of ob expression in a dietary model of obesity. J. Biol. Chem. 271, 9437-9440.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9437-9440
-
-
Collins, S.1
Surwit, R.S.2
-
62
-
-
0029974877
-
Adiposo tissue leptin production and plasma leptin kinetics in humans
-
Klein, S., Coppack, S. W., Mohamed-Ali, V., and Landt, M. (1996) Adiposo tissue leptin production and plasma leptin kinetics in humans. Diabetes 45, 984-987.
-
(1996)
Diabetes
, vol.45
, pp. 984-987
-
-
Klein, S.1
Coppack, S.W.2
Mohamed-Ali, V.3
Landt, M.4
-
63
-
-
0029941697
-
Radioimmunoassay of leptin in human plasma
-
Ma, Z., Gingerich, R. L., Santiago, J. V., Klein, S., Smith, C. H., and Landt, M. (1996) Radioimmunoassay of leptin in human plasma. Clin. Chem. 42, 942-946.
-
(1996)
Clin. Chem.
, vol.42
, pp. 942-946
-
-
Ma, Z.1
Gingerich, R.L.2
Santiago, J.V.3
Klein, S.4
Smith, C.H.5
Landt, M.6
-
64
-
-
0029746041
-
Serum leptin in children with obesity: Relationship to gender and development
-
Hassink, S. G., Sheslow, D. V., de Lancey, E., Opentanova, I., Considine, R. V., and Caro, J. F. (1996) Serum leptin in children with obesity: Relationship to gender and development. Pediatrics 98, 201-203.
-
(1996)
Pediatrics
, vol.98
, pp. 201-203
-
-
Hassink, S.G.1
Sheslow, D.V.2
De Lancey, E.3
Opentanova, I.4
Considine, R.V.5
Caro, J.F.6
-
65
-
-
0029157428
-
Transient increase in obese gene expression after food intake or insulin administration
-
Saladin, R., De Vos, P., Guerre-Millo, M., Leturque, A., Girard, J., Staels, B., and Auwerx, J. (1995) Transient increase in obese gene expression after food intake or insulin administration. Nature 377, 527-529.
-
(1995)
Nature
, vol.377
, pp. 527-529
-
-
Saladin, R.1
De Vos, P.2
Guerre-Millo, M.3
Leturque, A.4
Girard, J.5
Staels, B.6
Auwerx, J.7
-
66
-
-
0029021599
-
Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake
-
De Vos, P., Saladin, R., Auwerx, J., and Staels, B. (1995) Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J. Biol. Chem. 270, 15,958-15,961.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15958-15961
-
-
De Vos, P.1
Saladin, R.2
Auwerx, J.3
Staels, B.4
-
67
-
-
0028972884
-
Dexamethasone regulates obese expression in isolated rat adipocytes
-
Murakami, T., Iida, M., and Shima, K. (1995) Dexamethasone regulates obese expression in isolated rat adipocytes. Biochem. Biophys. Res. Comm. 214, 1260-1267.
-
(1995)
Biochem. Biophys. Res. Comm.
, vol.214
, pp. 1260-1267
-
-
Murakami, T.1
Iida, M.2
Shima, K.3
-
68
-
-
0029976448
-
Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP
-
Slicker, L. J., Sloop, K. W., Surface, P. L., Kriauciunas, A., LaQuier, F., Manetta, J., Bue-Valleskey, J., and Stephens, T. W. (1996) Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP. J. Biol. Chem. 271, 5301-5304.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5301-5304
-
-
Slicker, L.J.1
Sloop, K.W.2
Surface, P.L.3
Kriauciunas, A.4
LaQuier, F.5
Manetta, J.6
Bue-Valleskey, J.7
Stephens, T.W.8
-
69
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., and Burn, P. (1995) Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269, 546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
70
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas, J. L., Gajiwala, K. S., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R. L., Burley, S. K., and Friedman, J. M. (1995) Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269, 543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
71
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Hecht, R., Winters, D., Boone, T., and Collins, F. (1995) Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269, 540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
Collins, F.7
-
72
-
-
0029098589
-
The role of neuropeptide Y in the antiobesity action of the obese gene product
-
Stephens, T. W., Basinski, M., Bristow, P. K., Bue-Valleskey, J. M., Burgett, S. G., Craft, L., Hale, J., Hoffmann, J., Hsiung, H. M., and Kriauciunas, A. (1995) The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377, 530-532.
-
(1995)
Nature
, vol.377
, pp. 530-532
-
-
Stephens, T.W.1
Basinski, M.2
Bristow, P.K.3
Bue-Valleskey, J.M.4
Burgett, S.G.5
Craft, L.6
Hale, J.7
Hoffmann, J.8
Hsiung, H.M.9
Kriauciunas, A.10
-
73
-
-
0024792988
-
Experimental obesity: A homcostatic failure due to defective nutrient stimulation of the sympathetic nervous system
-
Bray, G. A., York, D. A., and Fisler, J. S. (1989) Experimental obesity: A homcostatic failure due to defective nutrient stimulation of the sympathetic nervous system. Vitamins Hormones 45, 1-125.
-
(1989)
Vitamins Hormones
, vol.45
, pp. 1-125
-
-
Bray, G.A.1
York, D.A.2
Fisler, J.S.3
-
74
-
-
0032548825
-
Obesity and the hypothalamus: Novel peptides for new pathways
-
Flier, J. S. and Maratos-Flier, E. (1998) Obesity and the hypothalamus: Novel peptides for new pathways. Cell 92, 437-440.
-
(1998)
Cell
, vol.92
, pp. 437-440
-
-
Flier, J.S.1
Maratos-Flier, E.2
-
75
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz, M. W., Baskin, D. G., Bukowski, T. R., Kuijper, J. L., Foster, D., Lasser, G., Prunkard, D. E., Porte, D., Jr., Woods, S. C., Seeley, R. J., and Weigle, D. S. (1996) Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45, 531-535.
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte D., Jr.8
Woods, S.C.9
Seeley, R.J.10
Weigle, D.S.11
-
76
-
-
0029946644
-
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
-
Erickson, J. C., Clegg, K. E., and Palmiter, R. D. (1996) Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381, 415-421.
-
(1996)
Nature
, vol.381
, pp. 415-421
-
-
Erickson, J.C.1
Clegg, K.E.2
Palmiter, R.D.3
-
77
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson, J. C., Hollopeter, G., and Palmiter, R. D. (1996) Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274, 1704-1707.
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
78
-
-
0032492893
-
Hypothalamic CART is a new anorectic peptide regulated by leptin
-
Kristensen, P., Judge, M. E., Thim, L., Ribel, U., Christjansen, K. N., Wulff, B. S., Clausen, J. T., Jensen, P. B., Madsen, O. D., Vrang, N., Larsen, P. J., and Hastrup, S. (1998) Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393, 72-76.
-
(1998)
Nature
, vol.393
, pp. 72-76
-
-
Kristensen, P.1
Judge, M.E.2
Thim, L.3
Ribel, U.4
Christjansen, K.N.5
Wulff, B.S.6
Clausen, J.T.7
Jensen, P.B.8
Madsen, O.D.9
Vrang, N.10
Larsen, P.J.11
Hastrup, S.12
-
79
-
-
0017164596
-
Reproductive hormonal function in the genetically obese (ob/ob) mouse
-
Swerdloff, R. S., Batt, R. A., and Bray, G. A. 1976. Reproductive hormonal function in the genetically obese (ob/ob) mouse. Endocrinology 98, 1359-1364.
-
(1976)
Endocrinology
, vol.98
, pp. 1359-1364
-
-
Swerdloff, R.S.1
Batt, R.A.2
Bray, G.A.3
-
80
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab, F. F., Lim, M. E., and Lu, R. (1996) Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nature Genet. 12, 318-320.
-
(1996)
Nature Genet.
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
81
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., and Flier, J. S. (1996) Role of leptin in the neuroendocrine response to fasting. Nature 382, 250-252.
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
-
82
-
-
0031014413
-
Early onset of reproductive function in normal female mice treated with leptin
-
Chehab, F. F., Mounzih, K., Lu, R., and Lim, M. E. (1997) Early onset of reproductive function in normal female mice treated with leptin. Science 275, 88-90.
-
(1997)
Science
, vol.275
, pp. 88-90
-
-
Chehab, F.F.1
Mounzih, K.2
Lu, R.3
Lim, M.E.4
-
83
-
-
0030868077
-
Leptin accelerates the onset of puberty in normal female mice
-
Ahima, R. S., Dushay, J., Flier, S. N., Prabakaran, D., and Flier, J. S. (1997) Leptin accelerates the onset of puberty in normal female mice. J. Clin. Invest. 99, 391-395.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 391-395
-
-
Ahima, R.S.1
Dushay, J.2
Flier, S.N.3
Prabakaran, D.4
Flier, J.S.5
-
84
-
-
0030980198
-
A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty
-
Mantzoros, C. S., Flier, J. S., and Rogol, A. D., (1997) A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty. J. Clin. Endocrinol. Metab. 82, 1066-1070.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 1066-1070
-
-
Mantzoros, C.S.1
Flier, J.S.2
Rogol, A.D.3
-
85
-
-
85047677586
-
Clinical review 90: Leptin and clinical medicine. A new piece in the puzzle of obesity
-
Bray, G. A. and York, D. A. (1997) Clinical review 90: Leptin and clinical medicine. A new piece in the puzzle of obesity. J. Clin. Endocrinol. Metab. 82, 2771-2776.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 2771-2776
-
-
Bray, G.A.1
York, D.A.2
-
86
-
-
0031438686
-
Leptin: Its role in obesity and beyond
-
Tritos, N. A. and Mantzoros, C. S. (1997) Leptin: Its role in obesity and beyond. Diabetologia 40, 1371-1379.
-
(1997)
Diabetologia
, vol.40
, pp. 1371-1379
-
-
Tritos, N.A.1
Mantzoros, C.S.2
-
87
-
-
0030250892
-
A role for leptin and its cognate receptor in hematopoiesis
-
Bennett, B. D., Solar, G. P., Yuan, J. Q., Mathias, J., Thomas, G. R., and Matthews, W. (1996) A role for leptin and its cognate receptor in hematopoiesis. Curr. Biol. 6, 1170-1180.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1170-1180
-
-
Bennett, B.D.1
Solar, G.P.2
Yuan, J.Q.3
Mathias, J.4
Thomas, G.R.5
Matthews, W.6
-
88
-
-
0029952911
-
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
-
Gainsford, T., Willson, T. A., Metcalf, D., Handman, E., McFarlane, C., Ng, A., Nicola, N. A., Alexander, W. S., and Hilton, D. J. (1996) Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Pro. Natl. Acad. Sci. USA 93, 14,564-14,568.
-
(1996)
Pro. Natl. Acad. Sci. USA
, vol.93
, pp. 14564-14568
-
-
Gainsford, T.1
Willson, T.A.2
Metcalf, D.3
Handman, E.4
McFarlane, C.5
Ng, A.6
Nicola, N.A.7
Alexander, W.S.8
Hilton, D.J.9
-
89
-
-
0031027475
-
Leptin stimulates fetal and adult erythroid and mycloid development
-
Mikhail, A. A., Beck, E. X., Shafer, A., Barut, B., Gbur, J. S., Zupancic, T. J., Schweitzer, A. C., Cloffi, J. A., Lacaud, G., Ouyang, B., Keller, G., and Snodgrass, H. R. (1997) Leptin stimulates fetal and adult erythroid and mycloid development. Blood 89, 1507-1512.
-
(1997)
Blood
, vol.89
, pp. 1507-1512
-
-
Mikhail, A.A.1
Beck, E.X.2
Shafer, A.3
Barut, B.4
Gbur, J.S.5
Zupancic, T.J.6
Schweitzer, A.C.7
Cloffi, J.A.8
Lacaud, G.9
Ouyang, B.10
Keller, G.11
Snodgrass, H.R.12
-
90
-
-
0030736770
-
Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells
-
Umemoto, Y., Tsuji, K., Yang, F. C., Ebihara, Y., Kaneko, A., Furukawa, S., and Nakahata, T. (1997) Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells. Blood 90, 3438-3443.
-
(1997)
Blood
, vol.90
, pp. 3438-3443
-
-
Umemoto, Y.1
Tsuji, K.2
Yang, F.C.3
Ebihara, Y.4
Kaneko, A.5
Furukawa, S.6
Nakahata, T.7
-
91
-
-
0029961204
-
The function of adipocytes in the bone marrow stroma: An update
-
Gimble, J. M., Robinson, C. E., Wu, X., and Kelly, K. A. (1996) The function of adipocytes in the bone marrow stroma: An update. Bone 19, 421-428.
-
(1996)
Bone
, vol.19
, pp. 421-428
-
-
Gimble, J.M.1
Robinson, C.E.2
Wu, X.3
Kelly, K.A.4
|