Genetic analysis by peptide nucleic acid affinity MALDI-TOF mass spectrometry

Nature Biotechnology

Volumn 15, Issue 13, 1997, Pages 1368-1372

  Griffin, Timothy J ^a   Tang, Wei ^a   Smith, Lloyd M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Genomics; Polymorphism

Indexed keywords

DNA; MONOPHENOL MONOOXYGENASE; NUCLEIC ACID; PEPTIDE;

ARTICLE; DNA FINGERPRINTING; DNA POLYMORPHISM; EXON; GENETIC ANALYSIS; GENOME; HUMAN; MASS SPECTROMETRY; NUCLEIC ACID HYBRIDIZATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN NUCLEIC ACID INTERACTION;

ALLELES; AMINO ACID SEQUENCE; BASE SEQUENCE; DNA; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MOLECULAR SEQUENCE DATA; MONOPHENOL MONOOXYGENASE; NUCLEIC ACID HYBRIDIZATION; NUCLEIC ACID PROBES; NUCLEIC ACIDS; PEPTIDE FRAGMENTS; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0031437217     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1297-1368     Document Type: Article

References (24)

1. Forrest, S., Cotton, R., Landegren, U., and Southern, E. 1995. How to find all those mutations. Nature Genet. 10:375-376.
2. Caskey, C.T. 1987. Disease diagnosis by recombinant DNA methods. Science 236:1223-1229.
3. Landegren, U., Kaiser, R., Caskey, C.T., and Hood, L. 1988. DNA diagnostics-molecular techniques and automation. Science 242:229-237.
4. Cotton, R. 1989. Detection of single base changes in nucleic acids. J. Biochem. 263:1-10.
5. Saiki, R., Walsh, P.S., Levenson, C., and Erlich, H. 1989. Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes. Proc. Nat. Acad. Sci. USA 86:6230-6234.
6. Wallace, B., Shaffer, J., Murphy, R.F., Bonner, J., Hirose, T., and Ikatura, K. et al. 1979. Hybridization of synthetic oligodeoxy-ribonucleotides to Φχ 174 DNA: the effect of a single base pair mismatch. Nucl. Acids. Res. 6:3543-3557.
7. Zhang, Y., Coyne, M., Will, S., Levenson, C., and Kawasaki, E. 1991. Single-base mutational analysis of cancer and genetic diseases using membrane bound modified oligonucleotides. Nucl. Acids Res. 19:3929-3933.
8. Guo, Z., Guilfoyle, R., Thiel, A., Wang, R., and Smith, L.M. 1994. Direct fluorescence analysis of genetic polymorphisms by hybridization with oligonucleotide arrays on glass supports. Nucl. Acids Res. 22:5456-5465.
9. Hillenkamp, F., Karas, M., Beavis, R., and Chait, B. 1991. Matrix-assisted laser desorption-ionization mass spectrometry of biopolymers. Anal. Chem. 63:1193A-1203A.
10. Karas, M., Bachmann, D., Bahr, U., and Hillenkamp, F. 1987. Matrix-assisted ultraviolet laser desorption of non-volatile compounds. Int. J. Mass Spectrom. Ion Phys. 78:53-68.
11. Chou, C., Bingham, S., and Williams, P. 1996. Affinity methods for purification of DNA sequencing reaction products for mass spectrometric analysis. Rapid Commun. Mass Spectrom. 10:1410-1414.
12. Köster, H., Tang, K., Fu, D., Braun, A., van den Boom, D., Smith, C.L., et al. 1996. A strategy for rapid and efficient DNA sequencing by mass spectrometry. Nature Biotechnology 14:1123-1128.
13. Girault, S., Chassaing, G., Biais, J., Brunot, A., and Bolbach, G. 1996. Coupling of MALDI-TOF mass analysis to the separation of biotinylated peptides by magnetic streptavidin beads. Anal. Chem. 68:2122-2126.
14. Tang, K., Fu, D., Kotter, S., Cotter, R.J., Cantor, C., and Koster, H. 1995. Matrix-assisted laser desorption/ionization mass spectrometry of immobilized duplex DNA probes. Nucl. Acids Res. 23:3126-3131.
15. Jurinke, C., van den Boom, B., Jacob, A., Tang, K., Wort, R., and Koster, H. 1996. Analysis of ligase chain reaction products via matrix-assisted laser desorption/ionization time-of-flight-mass spectrometry. Anal. Biochem. 237:174-181.
16. Nielsen, P, Egholm, M., Berg, R., and Buchardt, O. 1991. Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 254:1497-1500.
17. Egholm, M., Buchardt, O., Nielsen, P., and Berg, R. 1992. Peptide nucleic acids (PNA): oligonucleotide analogues with an achiral peptide backbone. J. Am. Chem. Soc. 114:1895-1897.
18. Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S.M., Driver, D., et al. 1993. PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen bonding rules. Nature 365:566-568.
19. Tomac, S., Sarkar, M., Ratilainen, T., Wittung, P., Nielsen, P., Borden, B., and Graslund, A. 1996. Ionic effects on the stability and conformation of peptide nucleic acid complexes. J. Am. Chem. Soc. 118:5544-5552.
20. Butler, J., Jiang-Baucom, P., Huang, M., Belgrader, P., and Girard, J. 1996. Peptide nucleic acid characterization by MALDI-TOF mass spectrometry. Anal. Chem. 68:3283-3287.
21. Giebel, L., Strunk, K., and Spritz, R. 1991. Organization and nucleotide sequence of the human tyrosinase gene and a truncated tyrosinase-related segment. Genomics 9:435-445.
22. Tripathi, R., Strunk, K., Giebel, L., Weleber, R., and Spritz. R. 1992. Tyrosinase gene mutations in type I (tyrosinase-deficient) oculocutaneous albinism define two clusters of missense substitutions. Am. J. Med. Genet. 43:865-871.
23. Wu, K., Steding, A., and Becker, C. 1993. Matrix-assisted laser desorption time-of-flight mass spectrometry of oligonucleotides using 3-hydroxypicolinic acid as an ultraviolet-sensitive matrix. Rapid Commun. Mass Spectrom. 7:142-146.
24. Zhu, L., Parr, G., Fitzgerald, M., Nelson, C., and Smith, L.M. 1995. Oligonucleotide fragmentation in MALDI/TOF mass spectrometry using 355 nm radiation. J. Am. Chem. Soc. 117:6048-6056.