A flexible and positively charged PNA analogue with an ethylene-linker to the nucleobase: Synthesis and hybridization properties

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 10, 1996, Pages 1083-1088

  Hyrup, Birgitte ^c   Egholm, Michael ^b   Buchardt, Ole ^d   Nielsen, Peter E ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b PERKINELMER INC   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; AMIDE; CARBONYL DERIVATIVE; COMPLEMENTARY DNA; DOUBLE STRANDED DNA; DRUG ANALOG; ETHYLENE; NUCLEIC ACID BASE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; OLIGOMER; SINGLE STRANDED DNA; THYMINE;

ARTICLE; BASE PAIRING; CIRCULAR DICHROISM; DNA DRUG COMPLEX; DNA HYBRIDIZATION; DRUG CONFORMATION; DRUG SYNTHESIS; MASS SPECTROMETRY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0029937476     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00176-X     Document Type: Article

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