Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration

Journal of Neuroscience

Volumn 18, Issue 24, 1998, Pages 10287-10296

  Sriram, Krishnan ^a,b   Shankar, Susarla K ^a,b   Boyd, Michael R ^a,b   Ravindranath, Vijayalakshmi ^a,b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Brain; Excitatory amino acids; Glutathione; L BOAA; Mitochondrial electron transport; NADH ubiquinone 1 oxidoreductase (complex I); Oxidative stress; Protein thiol oxidation

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; AMPA RECEPTOR ANTAGONIST; BETA N OXYLAMINOALANINE; EXCITATORY AMINO ACID; GLUTATHIONE; NEUROTOXIN; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; ELECTRON TRANSPORT; ENZYME INHIBITION; LATHYRISM; LUMBAR SPINAL CORD; MALE; MITOCHONDRION; MOTOR NEURON DISEASE; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

EID: 0032535398     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-24-10287.1998     Document Type: Article

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