-
1
-
-
0026563077
-
MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8
-
König, R., L.-Y. Huang, and R. N. Germain. 1992. MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature 356:796.
-
(1992)
Nature
, vol.356
, pp. 796
-
-
König, R.1
Huang, L.-Y.2
Germain, R.N.3
-
2
-
-
0026535396
-
Species-specific binding of CD4 to the β2 domain of major histocompatibility complex class II molecules
-
Vignali, D. A. A., J. Moreno, D. Schiller, and G. J. Hämmerling. 1992. Species-specific binding of CD4 to the β2 domain of major histocompatibility complex class II molecules. J. Exp. Med. 175:925.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 925
-
-
Vignali, D.A.A.1
Moreno, J.2
Schiller, D.3
Hämmerling, G.J.4
-
3
-
-
0026600191
-
2 domain of HLA-DR molecules
-
2 domain of HLA-DR molecules. Nature 356:799.
-
(1992)
Nature
, vol.356
, pp. 799
-
-
Cammarota, G.1
Scheirle, A.2
Takacs, B.3
Doran, D.M.4
Knorr, R.5
Bannwarth, W.6
Guardiola, J.7
Sinigaglia, F.8
-
4
-
-
0029150969
-
Involvement of both major histocompatibility complex class II α and β chains in CD4 function indicates a role for ordered oligomerization in T cell activation
-
König, R., X. Shen, and R. N. Germain. 1995. Involvement of both major histocompatibility complex class II α and β chains in CD4 function indicates a role for ordered oligomerization in T cell activation. J. Exp. Med. 182:779.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 779
-
-
König, R.1
Shen, X.2
Germain, R.N.3
-
6
-
-
0024425159
-
The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain
-
Shaw, A. S., K. E. Amrein, C. Hammond, D. F. Stern, B. M. Sefton, and J. K. Rose. 1989. The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain. Cell 59:627.
-
(1989)
Cell
, vol.59
, pp. 627
-
-
Shaw, A.S.1
Amrein, K.E.2
Hammond, C.3
Stern, D.F.4
Sefton, B.M.5
Rose, J.K.6
-
8
-
-
0026681679
-
The T cell receptor as a multicomponent signaling machine: CD4/CD8 coreceptors and CD45 in T cell activation
-
Janeway, C. A., Jr. 1992. The T cell receptor as a multicomponent signaling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol. 10:645.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 645
-
-
Janeway C.A., Jr.1
-
9
-
-
0027333348
-
Tickling the TCR: Selective T cell functions stimulated by altered peptide ligands
-
Evavold, B. D., J. Sloan-Lancaster, and P. M. Allen. 1993. Tickling the TCR: selective T cell functions stimulated by altered peptide ligands. Immunol. Today 14:602.
-
(1993)
Immunol. Today
, vol.14
, pp. 602
-
-
Evavold, B.D.1
Sloan-Lancaster, J.2
Allen, P.M.3
-
10
-
-
0028988331
-
T cell receptor antagonists and partial agonists
-
Jameson, S. C., and M. J. Bevan. 1995. T cell receptor antagonists and partial agonists. Immunity 2:1.
-
(1995)
Immunity
, vol.2
, pp. 1
-
-
Jameson, S.C.1
Bevan, M.J.2
-
11
-
-
0029966057
-
Essential flexibility in the T-cell recognition of antigen
-
Kersh, G. J., and P. M. Allen. 1996. Essential flexibility in the T-cell recognition of antigen. Nature 222:495.
-
(1996)
Nature
, vol.222
, pp. 495
-
-
Kersh, G.J.1
Allen, P.M.2
-
12
-
-
0026434554
-
Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand
-
Evavold, B. D., and P. M. Allen. 1991. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 252:1308.
-
(1991)
Science
, vol.252
, pp. 1308
-
-
Evavold, B.D.1
Allen, P.M.2
-
13
-
-
0028956146
-
Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand
-
Windhagen, A., C. Scholz, P. Höllsberg, H. Fukaura, A. Sette, and D. A. Hafler. 1995. Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity 2:373.
-
(1995)
Immunity
, vol.2
, pp. 373
-
-
Windhagen, A.1
Scholz, C.2
Höllsberg, P.3
Fukaura, H.4
Sette, A.5
Hafler, D.A.6
-
14
-
-
0027298445
-
Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
-
Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1993. Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 363:156.
-
(1993)
Nature
, vol.363
, pp. 156
-
-
Sloan-Lancaster, J.1
Evavold, B.D.2
Allen, P.M.3
-
15
-
-
0028025705
-
Th2 cell clonal anergy as a consequence of partial activation
-
Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1994. Th2 cell clonal anergy as a consequence of partial activation. J. Exp. Med. 180:1195.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1195
-
-
Sloan-Lancaster, J.1
Evavold, B.D.2
Allen, P.M.3
-
16
-
-
0026503161
-
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor
-
De Magistris, M. T., J. Alexander, M. Coggeshall, A. Altman, F. C. A. Gaeta, H. M. Grey, and A. Sette. 1992. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 68:625.
-
(1992)
Cell
, vol.68
, pp. 625
-
-
De Magistris, M.T.1
Alexander, J.2
Coggeshall, M.3
Altman, A.4
Gaeta, F.C.A.5
Grey, H.M.6
Sette, A.7
-
17
-
-
0028289311
-
Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand
-
Evavold, B. D., J. Sloan-Lancaster, and P. M. Allen. 1994. Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand. Proc. Natl. Acad. Sci. USA 91:2300.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2300
-
-
Evavold, B.D.1
Sloan-Lancaster, J.2
Allen, P.M.3
-
18
-
-
0027409792
-
Peptide-major histocompalibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling
-
Racioppi, L., F. Ronchese, L. A. Matis, and R. N. Germain. 1993. Peptide-major histocompalibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling. J. Exp. Med. 177:1047.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1047
-
-
Racioppi, L.1
Ronchese, F.2
Matis, L.A.3
Germain, R.N.4
-
19
-
-
0027967385
-
Partial T cell signaling: Altered phospho-ζ and lack of Zap 70 recruitment in APL-induced T cell anergy
-
Sloan-Lancaster, J., A. S. Shaw, J. B. Rothbard, and P. M. Allen. 1994. Partial T cell signaling: altered phospho-ζ and lack of Zap 70 recruitment in APL-induced T cell anergy. Cell 79:913.
-
(1994)
Cell
, vol.79
, pp. 913
-
-
Sloan-Lancaster, J.1
Shaw, A.S.2
Rothbard, J.B.3
Allen, P.M.4
-
21
-
-
0031091732
-
Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses
-
La Face, D. M., C. Couture, K. Anderson, G. Shih, J. Alexander, A. Sette, T. Mustelin, A. Altman, and H. M. Grey. 1997. Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses. J. Immunol. 158:2057.
-
(1997)
J. Immunol.
, vol.158
, pp. 2057
-
-
La Face, D.M.1
Couture, C.2
Anderson, K.3
Shih, G.4
Alexander, J.5
Sette, A.6
Mustelin, T.7
Altman, A.8
Grey, H.M.9
-
22
-
-
0030218942
-
Altered T cell receptor ligands trigger a subset of early T cell signals
-
Rabinowitz, J. D., C. Beeson, C. Wülfing, K. Tate, P. M. Allen, M. M. Davis, and H. M. McConnell. 1996. Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity 5:125.
-
(1996)
Immunity
, vol.5
, pp. 125
-
-
Rabinowitz, J.D.1
Beeson, C.2
Wülfing, C.3
Tate, K.4
Allen, P.M.5
Davis, M.M.6
McConnell, H.M.7
-
23
-
-
0031048822
-
The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/ partial agonist properties of peptide-MHC molecule ligands
-
Madrenas, J., L. A. Chau, J. Smith, J. A. Bluestone, and R. N. Germain. 1997. The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/ partial agonist properties of peptide-MHC molecule ligands. J. Exp. Med. 185: 219.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 219
-
-
Madrenas, J.1
Chau, L.A.2
Smith, J.3
Bluestone, J.A.4
Germain, R.N.5
-
24
-
-
0030008145
-
Variant TCR ligands: New insights into the molecular basis of antigen-dependent signal transduction and T-cell activation
-
Madrenas, J., and R. N. Germain. 1998. Variant TCR ligands: new insights into the molecular basis of antigen-dependent signal transduction and T-cell activation. Semin. Immunol. 8:83.
-
(1998)
Semin. Immunol.
, vol.8
, pp. 83
-
-
Madrenas, J.1
Germain, R.N.2
-
25
-
-
0032563231
-
Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation
-
Kersh, E. N., A. S. Shaw, and P. M. Allen. 1998. Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation. Science 281:572.
-
(1998)
Science
, vol.281
, pp. 572
-
-
Kersh, E.N.1
Shaw, A.S.2
Allen, P.M.3
-
26
-
-
0023924962
-
Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma
-
Ballhausen, W. G., A. B. Reske-Kunz, B. Tourvieille, P. S. Ohashi, J. R. Parnes, and T. W. Mak. 1988. Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma. J. Exp. Med. 167:1493.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 1493
-
-
Ballhausen, W.G.1
Reske-Kunz, A.B.2
Tourvieille, B.3
Ohashi, P.S.4
Parnes, J.R.5
Mak, T.W.6
-
27
-
-
0026524203
-
Does CD4 help to maintain the fidelity of T cell receptor specificity?
-
Vignali, D. A. A., J. Moreno, D. Schiller, and G. J. Hämmerling. 1992. Does CD4 help to maintain the fidelity of T cell receptor specificity? Int. Immunol. 4:621.
-
(1992)
Int. Immunol.
, vol.4
, pp. 621
-
-
Vignali, D.A.A.1
Moreno, J.2
Schiller, D.3
Hämmerling, G.J.4
-
28
-
-
0028339767
-
Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor
-
Vignali, D. A. A., and J. L. Strominger. 1994. Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor. J. Exp. Med. 179:1945.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1945
-
-
Vignali, D.A.A.1
Strominger, J.L.2
-
29
-
-
0028238668
-
Specificity and flexibility in thymic selection
-
Jameson, S. C., K. A. Hogquist, and M. J. Bevan. 1994. Specificity and flexibility in thymic selection. Nature 369:750.
-
(1994)
Nature
, vol.369
, pp. 750
-
-
Jameson, S.C.1
Hogquist, K.A.2
Bevan, M.J.3
-
30
-
-
0028945329
-
Autologous rat myelin basic protein is a partial agonist that is converted into a full antagonist upon blockade of CD4: Evidence for the integration of efficacious and nonefficacious signals during T cell antigen recognition
-
Mannie, M. D., J. M. Rosser, and G. A. White. 1995. Autologous rat myelin basic protein is a partial agonist that is converted into a full antagonist upon blockade of CD4: evidence for the integration of efficacious and nonefficacious signals during T cell antigen recognition. J. Immunol. 154:2642.
-
(1995)
J. Immunol.
, vol.154
, pp. 2642
-
-
Mannie, M.D.1
Rosser, J.M.2
White, G.A.3
-
31
-
-
0029862940
-
Endogenous altered peptide ligands can affect peripheral T cell responses
-
Vidal, K., B. L. Hsu, C. B. Williams, and P. M. Allen. 1996. Endogenous altered peptide ligands can affect peripheral T cell responses. J. Exp. Med. 183:1311.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1311
-
-
Vidal, K.1
Hsu, B.L.2
Williams, C.B.3
Allen, P.M.4
-
32
-
-
0030863079
-
CD4 augments the response of a T cell to agonist but not to antagonist ligands
-
Hampl, J., Y.-h. Chien, and M. M. Davis 1997. CD4 augments the response of a T cell to agonist but not to antagonist ligands. Immunity 7:379.
-
(1997)
Immunity
, vol.7
, pp. 379
-
-
Hampl, J.1
Chien, Y.-H.2
Davis, M.M.3
-
33
-
-
0032145326
-
CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR
-
Leitenberg, D., Y. Boutin, S. Constant, and K. Bottomly. 1998. CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR. J. Immunol. 161:1194.
-
(1998)
J. Immunol.
, vol.161
, pp. 1194
-
-
Leitenberg, D.1
Boutin, Y.2
Constant, S.3
Bottomly, K.4
-
34
-
-
0027174663
-
Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides
-
Evavold, B. D., J. Sloan-Lancaster, B. L. Hsu, and P. M Allen. 1993. Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides. J. Immunol. 150:3131.
-
(1993)
J. Immunol.
, vol.150
, pp. 3131
-
-
Evavold, B.D.1
Sloan-Lancaster, J.2
Hsu, B.L.3
Allen, P.M.4
-
35
-
-
0026586413
-
Complete dissection of the Hb(64-76) determinant using Th1, Th2 clones, and T cell hybridomas
-
Evavold, B. D., S. G. Williams, B. L. Hsu, S. Buus, and P. M. Allen. 1992. Complete dissection of the Hb(64-76) determinant using Th1, Th2 clones, and T cell hybridomas. J. Immunol. 148:347.
-
(1992)
J. Immunol.
, vol.148
, pp. 347
-
-
Evavold, B.D.1
Williams, S.G.2
Hsu, B.L.3
Buus, S.4
Allen, P.M.5
-
36
-
-
0029961893
-
Structural basis for T cell recognition of altered peptide ligands: A single T cell receptor can productively recognize a large continuum of related ligands
-
Kersh, G. J., and P. M. Allen. 1996. Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands. J. Exp. Med. 134:1259.
-
(1996)
J. Exp. Med.
, vol.134
, pp. 1259
-
-
Kersh, G.J.1
Allen, P.M.2
-
38
-
-
0024535530
-
Characterization of a monoclonal antibody which detects all murine αβ T cell receptors
-
Kubo, R. T., W. Born, J. W. Kappler, P. Marrack, and M. Pigeon. 1989. Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J. Immunol. 142:2736.
-
(1989)
J. Immunol.
, vol.142
, pp. 2736
-
-
Kubo, R.T.1
Born, W.2
Kappler, J.W.3
Marrack, P.4
Pigeon, M.5
-
39
-
-
0024845198
-
Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a non-functional α-mRNA of BW5147 origin
-
Letoumeur, F., and B. Malissen. 1989. Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a non-functional α-mRNA of BW5147 origin. Eur. J. Immunol. 19:2269.
-
(1989)
Eur. J. Immunol.
, vol.19
, pp. 2269
-
-
Letoumeur, F.1
Malissen, B.2
-
41
-
-
0027257445
-
A kinase-independent function of Lck in potentiating antigen-specific T cell activation
-
Xu, H., and D. R. Littman. 1993. A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 74:633.
-
(1993)
Cell
, vol.74
, pp. 633
-
-
Xu, H.1
Littman, D.R.2
-
42
-
-
0032528486
-
TCR transgenic mice in which usage of transgenic α-and β-chains is highly dependent on the level of selecting ligand
-
Kersh, G. J., D. L. Donermeyer, K. E. Frederick, J. M. White, B. L. Hsu, and P. M. Allen. 1998. TCR transgenic mice in which usage of transgenic α-and β-chains is highly dependent on the level of selecting ligand. J. Immunol. 161: 585.
-
(1998)
J. Immunol.
, vol.161
, pp. 585
-
-
Kersh, G.J.1
Donermeyer, D.L.2
Frederick, K.E.3
White, J.M.4
Hsu, B.L.5
Allen, P.M.6
-
43
-
-
0033558365
-
TCR-independent pathways mediate the effects of antigen dose and altered peptide ligands on Th cell polarization
-
Grakoui, A., D. L. Donermeyer, O. Kanagawa, K. M. Murphy, and P. M. Allen. 1999. TCR-independent pathways mediate the effects of antigen dose and altered peptide ligands on Th cell polarization. J. Immunol. 162:1923.
-
(1999)
J. Immunol.
, vol.162
, pp. 1923
-
-
Grakoui, A.1
Donermeyer, D.L.2
Kanagawa, O.3
Murphy, K.M.4
Allen, P.M.5
-
44
-
-
0030927323
-
Making the T cell receptor go the distance: A topological view of T cell activation
-
Shaw, A. S., and M. L. Dustin. 1997. Making the T cell receptor go the distance: a topological view of T cell activation. Immunity 6:361.
-
(1997)
Immunity
, vol.6
, pp. 361
-
-
Shaw, A.S.1
Dustin, M.L.2
-
45
-
-
0030250114
-
Complex complexes: Signaling at the TCR
-
Wange, R. L., and L. E. Samelson. 1996. Complex complexes: signaling at the TCR. Immunity 5:197.
-
(1996)
Immunity
, vol.5
, pp. 197
-
-
Wange, R.L.1
Samelson, L.E.2
-
46
-
-
0032483559
-
A novel adaptor protein orchestrates receptor patterning and cyloskeletal polarity in T-cell contracts
-
Dustin, M. L., M. W. Olszowy, A. D. Holdorf, J. Li, S. Bromley, N. Desai, P. Widder, F. Rosenberger, P. A. van der Merwe, P. Allen, et al. 1998. A novel adaptor protein orchestrates receptor patterning and cyloskeletal polarity in T-cell contracts. Cell 94:667.
-
(1998)
Cell
, vol.94
, pp. 667
-
-
Dustin, M.L.1
Olszowy, M.W.2
Holdorf, A.D.3
Li, J.4
Bromley, S.5
Desai, N.6
Widder, P.7
Rosenberger, F.8
Van Der Merwe, P.A.9
Allen, P.10
-
47
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks, C. R., B. A. Freiberg, H. Kupfer, N. Sciaky, and A. Kupfer. 1998. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395:82.
-
(1998)
Nature
, vol.395
, pp. 82
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
48
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
Grakoui, A., S. K. Bromley, C. Sumen, M. M. Davis, A. S. Shaw, P. M. Allen, and M. L. Dustin. 1999. The immunological synapse: a molecular machine controlling T cell activation. Science 235:221.
-
(1999)
Science
, vol.235
, pp. 221
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
Allen, P.M.6
Dustin, M.L.7
-
49
-
-
0032438551
-
High-and low-potency ligands with similar affinities for the TCR: The importance of kinetics in TCR signaling
-
Kersh, G. J., E. N. Kersh, D. H. Fremont, and P. M. Allen. 1998. High-and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling. Immunity 9:817.
-
(1998)
Immunity
, vol.9
, pp. 817
-
-
Kersh, G.J.1
Kersh, E.N.2
Fremont, D.H.3
Allen, P.M.4
|