Molecular basis for p38 protein kinase inhibitor specificity

Biochemistry

Volumn 37, Issue 47, 1998, Pages 16573-16581

  Lisnock, JeanMarie ^a   Tebben, Andy ^a   Frantz, Betsy ^a   O'Neill, Edward A ^a   Croft, Gist ^a   O'Keefe, Stephen J ^a   Li, Bing ^a   Hacker, Candice ^a   De Laszlo, Stephen ^a   Smith, Anthony ^a   Libby, Brian ^a   Liverton, Nigel ^a   Hermes, Jeffrey ^a   LoGrasso, Philip ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; PYRROLE DERIVATIVE; SYNAPTOPHYSIN;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME PURIFICATION; INFLAMMATION; MOLECULAR CLONING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATE; BASE SEQUENCE; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; METHIONINE; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; PYRROLES; THREONINE;

EID: 0032564311     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981591x     Document Type: Article

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