Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5′-triphosphate

Biochemistry

Volumn 35, Issue 18, 1996, Pages 5641-5646

  Robinson, Megan J ^a   Harkins, Paul C ^b   Zhang, Jiandong ^b   Baer, Richard ^a   Haycock, John W ^c   Cobb, Melanie H ^a   Goldsmith, Elizabeth J ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; MYELIN BASIC PROTEIN; ONCOPROTEIN; SYNTHETIC PEPTIDE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; ESCHERICHIA COLI; KINETICS; LYSINE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MYELIN BASIC PROTEINS; NEOPLASM PROTEINS; PEPTIDES; POINT MUTATION; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; FELIS CATUS;

EID: 0029928988     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952723e     Document Type: Article

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