Gene activation by recruitment of the RNA polymerase II holoenzyme

Genes and Development

Volumn 10, Issue 18, 1996, Pages 2359-2367

  Farrell, Susan ^a   Simkovich, Natasha ^a   Wu, Yibing ^a   Barberis, Alcide ^b   Ptashne, Mark ^a  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

GAL11; GAL4; gene activation; RNA polymerase II holoenzyme

Indexed keywords

RNA POLYMERASE II;

ARTICLE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME BINDING; GENE ACTIVATION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

EID: 0029780704     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.18.2359     Document Type: Article

References (33)

1. Barberis, A., J. Pearlberg, N. Simkovich, S. Farrell, P. Reinagel, C. Bamdad, G. Sigal, and M. Ptashne. 1995. Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell 81: 359-368.
2. Carey, M. 1995. A holistic view of the complex. Curr. Biol. 5: 1003-1005.
3. Carey, M., H. Kakidani, J. Leatherwood, F. Mostashari, and M. Ptashne. 1989. An amino-terminal fragment of GAL4 binds DNA as a dimer. J. Mol. Biol. 209: 423-432.
4. Carey, M., Y.-S. Lin, M.R. Green, and M. Ptashne. 1990. A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature 345: 361-364.
5. Chatterjee, S. and K. Struhl. 1995. Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain. Nature 374: 820-822.
6. Conaway, R.C. and J.W. Conaway. 1993. General initiation factors for RNA polymerase II. Ann. Rev. Biochem. 62: 161-190.
7. Dean, J. and J.W. Schechter. 1978. Sickle-cell anemia: Molecular and cellular bases of therapeutic approaches. New Engl. J. Med. 299: 752-763, 804-811, 863-870.
8. Gill, G. and M. Ptashne. 1988. Negative effect of the transcriptional activator GAL4. Nature 334: 721-724.
9. Giniger, E. and M. Ptashne. 1987. Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit. Nature 330: 670-672.
10. Hengartner, C.J., Thompson, C.M., Zhang, J., Chao, D.M., Liao, S., Koleske, A.J., Okamura, S., and R.A. Young. 1995. Association of an activator with an RNA polymerase II holoenzyme. Genes & Dev. 9: 897-910.
11. Himmelfarb, H.J., J. Pearlberg, D.H. Last, and M. Ptashne. 1990. GAL11P: A yeast mutation that potentiates the effect of weak GAL4-derived activators. Cell 63: 1299-1309.
12. Kim, Y.J., S. Bjorklund, Y. Li, M.H. Sayre, and R.D. Kornberg. 1994. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599-608.
13. Klages, N. and M. Strubin. 1995. Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo. Nature 374: 822-823.
14. Koleske, A. and R.A. Young. 1994. An RNA polymerase II holoenzyme responsive to activators. Nature 368: 466-469.
15. _. 1995. The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem. Sci. 20: 113-116.
16. Koleske, A.J., S. Buratowski, M. Nonet, and R.A. Young. 1992. A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell 69: 883-894.
17. Lin, Y.-S., M. Carey, M. Ptashne, and M.R. Green. 1990. How different eukaryotic transcriptional activators can cooperate promiscuously. Nature 345: 359-361.
18. Nerlov, C. and E.B. Ziff. 1995. CCAAT/enhancer binding protein-α amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells. EMBO J. 14: 4318-4328.
19. Ptashne, M. 1988. How eukaryotic transcriptional activators work. Nature 335: 683-689.
20. _. 1992. A genetic switch: Phage lambda and higher organisms. Cell Press and Blackwell Scientific Publications, Cambridge, MA.
21. 6 zinc cluster proteins. Science 261: 909-911.
22. Rose, M.D., F. Winston, and P. Hieter. 1990. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
23. Ruden, D.M., J. Ma, Y. Li, K. Wood, and M. Ptashne. 1991. Generating yeast transcriptional activators containing no yeast protein sequences. Nature 350: 250-252.
24. Schiestl, R.H. and R.D. Gietz. 1989. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16: 339-346.
25. Sigal, G.B., C. Bamdad, A. Barberis, J. Strominger, and G.M. Whitesides. 1996. A self-assembled monolayer for the binding and study of histidine-tagged proteins by surface plasmon resonance. Anal. Chem. 68: 490-497.
26. Struhl, K. 1996. Chromatin structure and RNA polymerase II connection: Implications for transcription. Cell 84: 179-182.
27. Suzuki, Y., Y. Nogi, A. Abe, and T. Fukasawa. 1988. GAL11 protein, an auxiliary transcriptional activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae. Mol. Cell. Biol. 8: 4991-4999.
28. Thompson, C.M., A.J. Koleske, D.M. Chao, and R.A. Young. 1993. A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73: 1367-1375.
29. Wilson, C.J., D.M. Chao, A.N. Imbalzano, G.R. Schnitzler, R.E. Kingston, and R.A. Young. 1996. RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell 84: 235-244.
30. Wu, Y., R.J. Reece, and M. Ptashne. 1996. Quantitation of putative activator-target affinities predicts transcriptional activating potentials. EMBO J. 15: 3951-3963.
31. Xiao, H., J.D. Friesen, and J.T. Lis. 1995. Recruiting TATA-binding protein to a promoter: Transcriptional activation without an upstream activator. Mol. Cell. Biol. 15: 5757-5761.
32. Zawel, L. and D. Reinberg. 1995. Common themes in assembly and function of eukaryotic transcription complexes. Annu. Rev. Biochem. 64: 522-561.
33. Zhou, Y., X. Zhang, and R.H. Ebright. 1991. Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase. Nucleic Acids Res. 19: 6052.