Angiotensin II activates Stat5 through Jak2 kinase in cardiac myocytes

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 4, 1998, Pages 751-761

  McWhinney, Charlene D ^a   Dostal, David ^a   Baker, Kenneth ^a  

^a WEIS CENTER FOR RESEARCH   (United States)

Author keywords

Angiotensin II; JAK STAT pathway; Myocytes; Stat5

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; HEART MUSCLE CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALIA;

EID: 0032054531     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0639     Document Type: Article

References (66)

1. ARGETSINGER LS, CAMPBELL GS, YANG X, WITTHUHN BA, SILVENNOINEN O, IHLE JN, CARTER-SU C, 1993. Identification of Jak2 as a growth hormone receptor-associated tyrosine kinase. Cell 74: 237-244.
2. AZAM M, ERDJUMERT-BROMAGE H, KREIDER B, XIA M, QUELLE F, BASU R, SARIS C, TEMPST P, IHLE J, SCHINDLER C, 1995. Interleukin-3 signals through multiple isoforms of Stat5. EMBO J 14: 1402-1411.
3. BHAT GJ, THEKKUMKARA TJ, THOMAS WG, CONRAD KM, BAKER KM, 1994. Angiotensin II stimulates sis-inducing factor-like DNA binding activity. J Biol Chem 269: 31443-31449.
4. 1A cells. J Biol Chem 270: 19059-19065.
5. BOOZ GW, BAKER KM, 1996. Role of type 1 and type 2 angiotensin receptors in angiotensin II induced cardiomyocyte hypertrophy. Hypertension 28: 635-640.
6. +2 in angiotensin II-induced mitogenesis of cardiac fibroblasts. Am J Physiol 267 (Cell Physiol 36): C1308-C1318.
7. BRUCHSCHLEGAL G, HOLMER SR, JANDELEIT K, GRIMM D, MUDERS F, KROMER EP, RIEGGER GAJ, SCHUNKERT H, 1996. Blockage of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats. Hypertension 25: 250-259.
8. CARTER-SU C, 1996. The role of the growth hormone (GH) receptor and Jak1 and Jak2 kinases in the activation of Stats 1, 3, and 5 by GH. Mol Endocrinol 10: 519-533.
9. CHEN J, SADOWSKI H, KOHANSKI J, WANG L, 1997. Stat5 is a physiological substrate of the insulin receptor. Proc Natl Acad Sci USA 94: 2295-2300.
10. CHEN K, PALADUGU A, ALDAZ C, GOULD M, 1996. Cloning and chromosomal localization of the rat Stat5 and Yy1 genes. Cytogenet Cell Genet 74: 277-280.
11. DARNELL JE, 1996. Reflections on STAT3, STAT5 and STAT6 as fat STATs. Proc Natl Acad Sci USA 93: 6221-6224.
12. DARNELL JE, KERR IM, STARK GR, 1994. JAK-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1418.
13. DOSTAL DE, BAKER KM, 1995. Biochemistry, molecular biology, and potential roles of the cardiac reninangiotensin system. In: Dhalla NS, Beamish RE, Takeda M and Nagano M (eds) The Failing Heart. Philadelphia: Lippincott-Raven Publishers.
14. DUERR R, MCKIMAN D, GIM R, CLARK R, CHIEN K, ROSS J, 1996. Cardiovascular effects of insulin-like growth factor-1 and GH in chronic left ventricular failure in the rat. Circulation 93: 2188-2196.
15. GALSGAARD ED, 1996. Identification of a growth hormone-responsive Stat5-binding element in the rat insulin 1 gene. Mol Endocrinol 10: 652-660.
16. GUILLET-DENIAU I, BURNOL A, GIRALD J, 1997. Identification and localization of a skeletal muscle serotonin 5-HT2A receptor coupled to the JAK-STAT pathway. J Biol Chem 272: 14825-14829.
17. HIROTA H, YOSHIDA K, TAGA T, 1995. Continuous activation of gp130, a signal transducing receptor component for interleukin 6 related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA 92: 4862-4866.
18. HORVATH CM, DARNELL JE, 1997. The state of the STATs: recent developments in the study of signal transduction to the nucleus. Curr Opin Cell Biol 9: 233-239.
19. HUNTER T, 1995. Cytokines connections. Nature 366: 114-116.
20. IGARASHI K, GAROTTA G, OZMEN L, ZIEMIECKI Z, WILKS A, HARPUR A, LAMER AC, FINBLOOM DS, 1994. Interferon-γ-induces tyrosine phosphorylation of interferon-γ receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. J Biol Chem 269: 14333-14336.
21. IHLE JN, 1996. STATs: signal transducers and activators of transcription. Cell 84: 331-334.
22. KINOSHITA N, MINSHULL J, KIRSCHNER MW, 1995. The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development. Cell 83: 621-630.
23. KLINGMULLER U, BERGELSON S, HSIAO J, LODISH H, 1996. Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5. Proc Natl Acad Sci USA 93: 8324-8328.
24. KOJIMA H, NAKAJIMA K, HIRANO T, 1996. IL-6-inducible complexes on an IL-6 response element of the junB promoter contain Stat3 and 36 kDa CRE-like site binding sites. Oncogene 12: 547-554.
25. KUNISADA K, HIROTA H, FUJIO Y, MATSUI H, TANI Y, YAMAUCHI-TAKIHARA K, KISHIMOTO T, 1996. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes. Circulation 94: 2626-2632.
26. LEHMAN DW, PISHARODY S, FLICKINGER TW, COMMANE MA, SCHLESSINGER J, KERR IM, LEVY DE, STARK GR, 1996. Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor. Mol Cell Biol 16: 369-375.
27. LEUNG S, LI X, STARK GR, 1996. STATs find that hanging together can be stimulating. Science 273: 750-754.
28. LIN J, MIGONE T, TSANG M, FRIEDMAN M, WEATHERBEE J, ZHOU L, YAMAUCHI A, BLOOM E, MIETZ J, JOHNS S, 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleitrophy and reduncy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2: 331-339.
29. MABLEY JD, CHOONG-CHIN L, 1996. Factors involved in cardiogenesis and the regulation of cardiac-specific gene expression. Circ Res 79: 4-13.
30. 1 receptor. Nature 375: 247-250.
31. MEINKE A, BARAHMAN-POUR ??, WOHRI S, STOIBER D, DECKER T, 1996. Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons. Mol Cell Biol 16: 6937-6944.
32. MEYDAN N, GRUNBERGER T, DAI H, SHAHAR M, ARPAIA E, LAPIDOT Z, LEEDER J, FREEDMAN M, GAZIT A, LEVIZKI A, ROIFMAN C, 1996. Inhibition of acute lymphoblastic leukemia by a Jak-2 inhibitor. Nature 379: 645-648.
33. MCWHINNEY CD, HUNT RA, CONRAD KM, DOSTAL DE, BAKER KM, 1997. The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes. J Mol Cell Cardiol 29: 2513-2524.
34. MUI A, WAKAO H, KINOSHITA T, KITAMURA T, MIYAJIMA A, 1996. Suppression of interleukin-3-induced gene expression by a c-terminal truncated Stat5: role of Stat5 in proliferation. EMBO J 15: 2425-2433.
35. MUROI M, SUZUKI T, 1993. A role of protein kinase A in LPS-induced activation of NF-KB proteins of a mouse macrophage-like cell line, J774. Cellular Signaling 5: 289-298.
36. NAKAMURA N, CHIN H, MIYASAKA N, MIURA O, 1996. An epidermal growth factor receptor/Jak2 kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells. J Biol Chem 271: 19483-19488.
37. NOVAK U, MUI A, MIYAJIMA AL, PARADISO L, 1996. Formation of STAT5-containing DNA binding complexes in response to colony-stimulating factor-1 and platelet-derived growth factor. J Biol Chem 271: 18350-18354.
38. PALMER JN, HARTOGENSIS WE, PATTEN M, FORTUIN FD, LONG CS, 1995. Interleukin 1β induces cardiac myocyte growth, but inhibits cardiac flbroblast proliferation in culture. J Clin Invest 95: 2555-2564.
39. PAN J, FUKUDA K, KODAMA H, MAKINO S, TAKAHASHI T, SANO M, HORI S, OGAWA S, 1997. Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart. Circ Res 81: 611-617.
40. PENNICA D, KING KL, ISHAW K, RULLAMAS L, LUOH S, DARBONNE W, KNUTZON D, LCHEIN Y, BAKER J, WOOD WI, 1995. Expression cloning of cardiotrophin-1, a cytokine that induces cardiomyocyte hypertrophy. Proc Natl Acad Sci USA 92: 1142-1146.
41. QUELLE F, SATO N, WITTHUHN B, INHORN R, EDER M, MYAJIMA A, GRIFFIN J, IHLE J, 1994. Jak2 associates with the β chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol 14: 4335-4341.
42. RAM P, PARK S, CHOI H, WAXMAN D, 1996. Growth hormone activation of Stat1, Stat3 and Stat5 in rat liver. J Biol Chem 271: 5929-5940.
43. RIPPERGER J, FRITZ S, RICHTER K, HOCKE G, LOTTSPEICH F, FEY G, 1995. Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements. J Biol Chem 270: 29998-30006.
44. ROBINSON G, GOUILLEUX F, GRONER B, HENNIGHAUSSEN L, LIU X, 1995. Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin transduction in mouse mammary tissue. Proc Natl Acad Sci USA 92: 8831-8835.
45. SADOSHIMA J-L, XU Y, SLAYTER H, IZUMO S, 1993. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 75: 977-984.
46. SATO N, SAKAMAKI K, TERADA N, ARAI K, MIYAJIMA A, 1993. Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling. EMBO J 12: 4181-4189.
47. SCHINDLER C, DARNELL JE, 1995. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Ann Rev Biochem 64: 621-651.
48. STOCKLINE E, WISLER M, GOUILLEUX F, GRONER B, 1996. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383: 726-728.
49. TANAKA A, MATSUMORI A, WANG W, SASAYAMA S, 1994. An angiotensin II receptor antagonist reduces myocardial damage in an animal model of myocarditis. Circulation 90: 2051-2055.
50. TANNER JW, CHEN W, YOUNG RL, LONGMORE GD, SHAW AS, 1995. The conserved box 1 motif of cytokine receptors is required for association with JAK kinases. J Biol Chem 270: 6523-6530.
51. THAIK CM, CALDERONE A, COLUCCI WS, 1995. Interleukin-1β modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest 96: 1093-1099.
52. TIMMERMANS PB, WONG PC, CHIU AT, HERBLIN WF, 1991. Nonpeptide angiotensin II receptor antagonists. TIPS 12: 55-62.
53. VANDERKURR JA, WANG X, ZHANG L, CAMPBELL GS, ALLEVATO G, BILLESTRUP N, NORSTEDT G, CARTER-SU C, 1994. Domains of the growth hormone receptor required for association and activation of Jak2 tyrosine kinase. J Biol Chem 269: 21709-21710.
54. VIGNAIS M, SADOWSKI H, WATLING D, ROGERS N, GILMAN M, 1996. PDGF induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol 16: 1759-1769.
55. WAKAO H, HARADA N, KITAMURA T, MUI A, MIYAJIMA A, 1995. Interleukin-1 and erythropoietin activate STAT5/MGF via distinct pathways. EMBO J 14: 2527-2535.
56. WANG D, STRAVOPODIS D, TEGLUND S, KITAZAWA J, IHLE JN, 1996. Naturally occurring dominant negative variants of Stat5. Mol Cell Biol 16: 6141-6148.
57. WANG X, DARUS CJ, XU B, KOPCHICK S, IHLE J, 1996a. Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation. Mol Endocrinol 10: 1249-1260.
58. WANG X, DARUS C, KOPCHICK J, 1996b. Growth hormone promotes the association of transcription factor STAT5 with the growth hormone receptor. J Biol Chem 271: 19768-19773.
59. WEN Z, ZHONG Z, DARNELL JE, 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82: 241-250.
60. WINSTON LA, HUNTER T, 1995. JAK2, Ras, and Raf are required for activation of extracellular signal-related kinase/mitogen-activated protein kinase by growth hormone. J Biol Chem 270: 30837-30840.
61. WITTHUHN BA, QUELLE FW, SILVENNOINE O, YI T, TANG B, MURA O, IHLE JN, 1993. Jak2 associates with the erythropoietin receptor and is tyrosine phosphorylated following stimulation with erythropoietin. Cell 74: 227-236.
62. WONG PC, HART SD, ZASPEL AM, CHIU AT, ARDECKY RL, SMITH RD, TIMMERMANS PB, 1990. Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2). J Pharmacol Exp Ther 255: 584-592.
63. YAN H, KRISHMAN K, LIM JT, CONTILLO LG, KROLEWSKI JJ, 1996. Molecular characterization of an alpha interferon receptor 1 subunit domain required for Tyk2 binding and signal transduction. Mol Cell Biol 16: 2074-2082.
64. YOSHIMURA A, ICHIHARA M, KINIVO I, MORIVAMA M, COPELAND N, GILBERT N, JENKINS N, HARA T, MIYAJIMA A, 1996. Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. EMBO J 15: 1055-1063.
65. YUAN J, WEGENKA UM, LUTTICAN C, BUSCHMANN J, DECKER T, SCHINDLER C, HEINRICH PC, HORN F, 1994. The signaling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol Cell Biol 14: 1657-1668.
66. ZHAO Y, WAGNER F, FRANK S, KRAFT AS, 1995. The amino-terminus portion of the Jak2 kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor βc chain. J Biol Chem 270: 13814-13818.