The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 9, 1997, Pages 2513-2524

  McWhinney, Charlene D ^a   Hunt, Rachel A ^a   Conrad, Kathleen M ^a   Dostal, David E ^a   Baker, Kenneth M ^a  

^a WEIS CENTER FOR RESEARCH   (United States)

Author keywords

Angiotensin II; JAK STAT pathway; Ventricular myocytes

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN RECEPTOR; CYTOKINE; GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOTRANSFERASE; STAT1 PROTEIN; STAT3 PROTEIN; TYROSINE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME INHIBITION; HEART CELL CULTURE; HEART INFARCTION; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HYPERTENSION; IMMUNOPRECIPITATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALIA;

EID: 0031238627     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0489     Document Type: Article

References (42)

1. ARGETSINGER LS, CAMPBELL GS, YANG X, WITTHUHN BA, SILVENNOINEN O, IHLE JN, CARTER-SU C, 1993. Identification of Jak2 as a growth hormone receptor-associated tyrosine kinase. Cell 74: 237-244.
2. BHAT GJ, THEKKUMKARA TJ, THOMAS WG, CONRAD KM, BAKER KM, 1994. Angiotensin II stimulates sis-inducing factor-like DNA binding activity. J Biol Chem 269: 31443-31449.
3. 1A cells. J Biol Chem 270: 19059-19065.
4. BOOZ GW, BAKER KM, 1996. Role of type 1 and type 2 angiotensin receptors in angiotensin II induced cardiomyocyte hypertrophy. Hypertension 28: 635-640.
5. 2+ in angiotensin II-induced mitogenesis of cardiac fibroblasts. Am J Physiol 267 (Cell Physiol 36): C1308-C1318.
6. BUNGO M, GRAEVE L, GATSIOS P, KOJ A, HEINRICH P, TRAVIS J, KORDULA T, 1995. Identification of interleukin-6/ oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-I) promoter. Nucleic Acids Res 23: 5041-5047.
7. BRUCHSCHLEGAL G, HOLMER SR, JANDELEIT K, GRIMM D, MUDERS F, KROMER EP, RIEGGER GAJ, SCHUNKERT H, 1996. Blockage of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats. Hypertension 25: 250-259.
8. CHUA CC, HAMDY RC, CHUA BH, 1996. Angiotensin II induces TIMP-1 production in rat heart endothelial cells. Biochim Biophys Acta 1311: 175-180.
9. DARNELL JE, KERR IM, STARK GR, 1994. JAK-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1418.
10. DOSTAL DE, BAKER KM, 1995. Biochemistry, molecular biology, and potential roles of the cardiac renin-angiotensin system. In: Dhalla NS, Beamish RE, Takeda M, Nagano M (eds). The Failing Heart. Philadelphia: Lippincott-Raven Publishers, 275-295.
11. HIROTA H, YOSHIDA K, TAGA T, 1995. Continuous activation of gp130, a signal transducting receptor component for interleukin 6 related cytokines, causes myocardial hypertrophy in mice. Proc Natl Acad Sci USA 92: 4862-4866.
12. HUNTER T, 1995. Cytokine connections. Nature 366: 114-116.
13. IGARASHI K, GAROTTA G, OZMEN L, ZIEMIECKI Z, WILKS A, HARPUR A, LAMER AC, FINBLOOM DS, 1994. Interferon-γ-induces tyrosine phosphorylation of interferon-γ receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. J Biol Chem 269: 14333-14336.
14. IHLE JN, 1996. STATs: signal transducers and activators of transcription. Cell 84: 331-334.
15. KORDULA T, RIPPERGER J, MORELLA K, TRAVIS J, BAUMANN H, 1996. Two separate signal transducer and activators of transcription regulate transcription of the serine proteinase inhibitor-3 gene in hepatic cells. J Biol Chem 271: 6752-6757.
16. KOJIMA H, NAKAJIMA K, HIRANO T, 1996. IL-6-inducible complexes on an IL-6 response element of the junB promoter contain Stat3 and 36 kDa CRE-like site binding proteins. Oncogene 12: 547-554.
17. KUNISADA K, HIROTA H, FUJIO Y, MATSUI H, TANI Y, YAMAUCHI-TAKIHARA K, KISHIMOTO T, 1996. Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes. Circulation 94: 2626-2632.
18. LEHMAN DW, PISHARODY S, FLICKINGER TW, COMMANE MA, SCHLESSINGER J, KERR IM, LEVY DE, STARK GR, 1996. Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor. Mol Cell Biol 16: 369-375.
19. LIN C, BAKER KM, THEKKUMKARA TJ, DOSTAL DE, 1995. Sensitive bioassay for the detection and quantification of angiotensin II in tissue culture medium. Biotechniques 18: 1015-1018.
20. MABLEY JD, CHOONG-CHIN L, 1996. Factors involved in cardiogenesis and the regulation of cardiac-specific gene expression. Circ Res 79: 4-13.
21. 1 receptor. Nature 375: 247-250.
22. MEYDAN N, GRUNBERGER T, DAI H, SHAHAR M, ARPAIA E, LAPIDOT Z, LEEDER J, FREEDMAN M, GAZIT A, LEVIZKI A, ROIFMAN C, 1996. Inhibition of acute lymphoblastic leukemia by a Jak-2 inhibitor. Nature 379: 645-648.
23. MUROI M, SUZUKI T, 1993. A role of protein kinase A in LPS-induced activation of NF-κB proteins of a mouse macrophage-like cell line, J774. Cell Signaling 5: 289-298.
24. PALMER JN, HARTOGENSIS WE, PATTEN M, FORTUIN FD, LONG CS, 1995. Interleukin 1β induces cardiac myocyte growth, but inhibits cardiac flbroblast proliferation in culture. J Clin Invest 95: 2555-2564.
25. PENNICA D, KING KL, ISHAW K, RULLAMAS L, LUOH S, DARBONNE W, KNUTZON D, LCHEIN Y, BAKER J, WOOD WI, 1995. Expression cloning of cardiotrophin-1, a cytokine that induces cardiomyocyte hypertrophy. Proc Natl Acad Sci USA 92: 1142-1146.
26. QUELLE FG, SATO N, WITTHUHN B, INHORN RC, EDER M, MYAJIMA A, GRIFFIN J, IHLE J, 1994. Jak2 associates with the β chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol 14: 4335-4341.
27. RAM P, PARK S, CHOI H, WAXMAN DJ, 1996. Growth hormone activation of Stat1, Stat3 and Stat5 in rat liver. J Biol Chem 271: 5929-5940.
28. SADOSHIMA J-L, XU Y, SLAYTER HS, IZUMO S, 1993. Auto-crine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 75: 977-984.
29. SCHINDLER C, DARNELL JE, 1995. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem 64: 621-651.
30. TANAKA A, MATSUMORI A, WANG W, SASAYAMA S, 1994. An angiotensin II receptor antagonist reduces myocardial damage in an animal model of myocarditis. Circulation 90: 2051-2055.
31. TANNER JW, CHEN W, YOUNG RL, LONGMORE GD, SHAW AS, 1995. The conserved box 1 motif of cytokine receptors is required for association with JAK kinases. J Biol Chem 270: 6523-6530.
32. THAIK CM, CALDERONE A, COLUCCI WS, 1995. Interleukin-1β modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest 96: 1093-1099.
33. TIMMERMANS PB, WONG PC, CHIU AT, HERBLIN WF, 1991. Nonpeptide angiotensin II receptor antagonists. TIPS 12: 55-62.
34. VANDERKURR JA, WANG X, ZHANG L, CAMPBELL GS, ALLEVATO G, BILLESTRUP N, NORSTEDT G, CARTER-SU C, 1994. Domains of the growth hormone receptor required for association and activation of Jak2 tyrosine kinase. J Biol Chem 269: 21709-2171?.
35. VIGNAIS M, SADOWSKI H, WATLING D, ROGERS N, GILMAN M, 1996. PDGF induces phosphorylation of multiple JAK family kinases and STAT proteins. Mol Cell Biol 16: 1759-1769.
36. WEN Z, ZHONG Z, DARNELL JE, 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82: 241-250.
37. WINSTON LA, HUNTER T, 1995. JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone. J Biol Chem 270: 30837-30840.
38. WITTHUHN BA, QUELLE FW, SILVENNOINE O, YI T, TANG B, MURA O, IHLE JN, 1993. Jak2 associates with the erythropoietin receptor and is tyrosine phosphorylated following stimulation with erythropoietin. Cell 74: 227-236.
39. WONG PC, HART SC, ZASBEL AM, 1990. Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2). J Pharmacol Exp Ther 255: 584-592.
40. YUAN J, WEGENKA UM, LUTTICAN C, BUSCHMANN J, DECKER T, SCHINDLER C, HEINRICH PC, HORN F, 1994. The signaling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol Cell Biol 14: 1657-1668.
41. YAN H, KRISHMAN K, LIM JT, CONTILLO LG, KROLEWSKI JJ, 1996. Molecular characterization of an alpha interferon receptor 1 subunit domain required for Tyk2 binding and signal transduction. Mol Cell Biol 16: 2074-2082.
42. ZHAO Y, WAGNER F, FRANK S, KRAFT AS, 1995. The amino-terminus portion of the Jak2 kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor βc chain. J Biol Chem 270: 13814-13818.