Cardiovascular effects of insulin-like growth factor-1 and growth hormone in chronic left ventricular failure in the rat

Circulation

Volumn 93, Issue 12, 1996, Pages 2188-2196

  Duerr, Robert L ^a   McKirnan, M Dan ^b   Gim, Ronald D ^a   Clark, Ross G ^c   Chien, Kenneth R ^a   Ross Jr , John ^a,d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cardiac output; growth substances; hypertrophy; myocardial infarction; remodeling

Indexed keywords

GROWTH HORMONE; HUMAN GROWTH HORMONE; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART OUTPUT; HEART VENTRICLE REMODELING; HORMONAL THERAPY; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029949746     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.93.12.2188     Document Type: Article

References (51)

1. Anversa P, Loud AV, Levicky V, Guideri G. Left ventricular failure induced by myocardial infarction, I: myocyte hypertrophy. Am J Physiol. 1985;248:H876-H882.
2. Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction: experimental observations and clinical implications. Circulation. 1990;81:1161-1172.
3. Zimmer HG, Gerdes AM, Lortet S, Mall G. Changes in heart function and cardiac cell size in rats with chronic myocardial infarction. J Mol Cell Cardiol. 1990;22:1231-1243.
4. Ono S, Bhargava V, Ono S, Mao L, Hagan G, Rockman H, Ross J Jr. In vivo assessment of left ventricular remodelling after myocardial infarction by digital videocontrast angiography in the rat. Cardiovasc Res. 1994;28:349-357.
5. Hutchins GM, Bulkley BH. Infarct expansion versus extension: two different complications of acute myocardial infarction. Am J Cardiol. 1978;41:1127-1132.
6. McKay RG, Pfeffer MA, Pasternak RC, Markis JE, Cone PC, Shoichiro N, Alderman JD, Ferguson JJ, Safian RD, Grossman W. Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion. Circulation. 1986;74:693-702.
7. Pfeffer JM, Pfeffer MA, Fletcher PJ, Braunwald E. Progressive ventricular remodeling in rat with myocardial infarction. Am J Physiol. 1991;260:H1406-H1414.
8. Weisman HF, Bush DE, Mannisi JA, Bulkley BH. Global cardiac remodeling after acute myocardial infarction: a study in the rat model. J Am Coll Cardiol. 1985;5:1355-1362.
9. Anversa P, Beghi C, Kikkawa Y, Olivetti G. Myocardial infarction in rats: infarct size, myocyte hypertrophy, and capillary density. Circ Res. 1986;58:26-37.
10. Pfeffer JM, Pfeffer MA, Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res. 1985;57:84-95.
11. Pfeffer MA, Braunwald E, Moyé LA, Basta L, Brown EJ Jr, Cuddy TE, Davis BR, Geltman EM, Goldman S, Flaker GC, Klein M, Lamas GA, Packer M, Rouleau J, Rouleau JL, Rutherford J, Wertheimer JH, Hawkins CM, on behalf of the SAVE Investigators. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement trial. N Engl J Med. 1992;327:669-677.
12. The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med. 1991;325:293-302.
13. Schieffer B, Wirger A, Meybrunn M, Seitz S, Holtz J, Riede UN, Drexler H. Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat. Circulation. 1994;89:2273-2282.
14. Duerr R, Huang S, Miraliakbar HR, Clark RG, Chien K, Ross J Jr. Insulin-like growth factor I enhances ventricular hypertrophy and function during the onset of experimental cardiac failure. J Clin Invest. 1995;95:619-627.
15. Powell-Braxton L, Hollingshead P, Warburton C, Dowd M, Pitts-Meek S, Dalton D, Gillett N, Stewart T, IGF-1 is required for normal embryonic growth in mice. Genes Dev. 1993;12B:2609-2617.
16. Engelmann G, Boehm KD, Haskell JF, Khairallah PA, Ilan J. Insulin-like growth factors and neonatal cardiomyocyte development: ventricular gene expression and membrane receptor variations in normotensive and hypertensive rats. Mol Cell Endocrinol. 1989;63:648-657.
17. Ito H, Hiroe M, Hirata Y, Motoyoshi T, Adachi S, Masayoshi S, Koike A, Nogami A, Marumo F. Insulin like growth factor-1 induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes. Circulation. 1993;87: 1715-1721.
18. Fuller J, Mynett JR, Sugden PH. Stimulation of cardiac protein synthesis by insulin-like growth factors. Biochem J. 1992;282:85-90.
19. Wåhlander H, Isgaard J, Jennische E, Friberg E. Left ventricular insulin-like growth factor I increases in early renal hypertension. Hypertension. 1992;19:25-32.
20. Donohue TJ, Dworkin LD, Lango MN, Fliegner K, Lango RP, Benstein JA, Slater WR, Catanese VM. Induction of myocardial insulin-like growth factor-I gene expression in left ventricular hypertrophy. Circulation. 1994;89:799-809.
21. Rubin SA, Buttrick P, Malhotra A, Melmed S, Fishbein MC. Cardiac physiology, biochemistry and morphology in response to excess growth hormone in the rat. Mol Cell Cardiol. 1990;22: 429-438.
22. Isgaard J, Nilsson A, Vikman K, Isaksson OGP. Growth hormone regulates the level of insulin-like growth factor-I mRNA in rat skeletal muscle. J Endocrinol. 1989;120:107-112.
23. Gosteli-Peter MA, Winterhalter KH, Schmid C, Froesch ER, Zapf J. Expression and regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein messenger ribonucleic acid levels in tissues of hypophysectomized rats infused with IGF-I and growth hormone. Endocrinology. 1994;135:2558-2567.
24. Guler HP, Zapf J, Scheiwiller E, Froesch ER. Recombinant human insulin-like growth factor 1 stimulates growth and has distinct effects on organ size in hypophysectomized rats. Proc Natl Acad Sci U S A. 1988;85:4889-4893.
25. Clark RG, Mortensen DL, Carlsson LMS, Robinson ICAF. Insulin-like growth factor-1 and growth hormone (GH) have distinct and overlapping anabolic effects in GH-deficient rats. Endocrine. 1995; 3:297-304.
26. Zapf J, Schmid C, Guler HP, Waldvoger M, Hauri C, Futo E, Hossenlopp P, Binoux M, Froesch ER. Regulation of binding proteins for insulin like growth factor I (IGF) in humans: increased expression of IGF binding protein 2 during IGF-I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia. J Clin Invest. 1990;86:952-961.
27. Kupfer SR, Underwood LE, Baxter RC, Clemmons DR. Enhancement of the anabolic effects of growth hormone and insulin-like growth factor I by use of both agents simultaneously. J Clin Invest. 1993;91:391-396.
28. Young SCJ, Underwood LE, Celinker A, Clemmons DR. Effects of recombinant insulin like growth factor I (IGF-1) and growth hormone on serum IGF-1 binding proteins in calorically restricted adults. J Clin Endocrinol Metab. 1992;75:603-608.
29. Fletcher PJ, Pfeffer JM, Pfeffer MA, Braunwald E. Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction: effects on systolic function. Circ Res. 1981;49:618-626.
30. Wicker C, Tarazi RC. Importance of injection site for coronary blood flow determinations by microspheres in rats. Am J Physiol. 1980;242:H94-H97.
31. Glenny RW, Bernard S, Brinkley M. Validation of fluorescent-labeled microspheres for measurement of regional organ perfusion. J Appl Physiol. 1993;74:2585-2597.
32. Dodge HT, Sandler H, Ballew DW, Lord JD. The use of biplane angiocardiography for the measurement of left ventricular volume in man. Am Heart J. 1960;60:762-776.
33. Omens JH, Rockman HA, Covell JW. Passive ventricular mechanics in tight-skin mice. Am J Physiol. 1994;35:H1169-H1176.
34. Yin RC, Spurgeon HA, Rakusan K, Weisfeldt ML, Lakatta EG. Use of tibial length to quantify cardiac hypertrophy: application in the aging rat. Am J Physiol. 1982;243:H941-H947.
35. Oh B-H, Ono S, Rockman HA, Ross J. Myocardial hypertrophy in the ischemic zone induced by exercise in rats after coronary reperfusion. Circulation. 1993;87:598-607.
36. Fishbein MC, Maclean D, Maroko PR. The histolopathologic evolution of myocardial infarction. Chest. 1978;73:843-849.
37. Lieberman SA, Bukar J, Chen SA, Celniker AC, Compton PG, Cook J, Albu J, Perlman AJ, Hoffman AR. Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans. J Clin Endocrinol Metab. 1992;75:30-36.
38. Oster MH, Fielder PJ, Levin N, Cronin MJ. Adaptation of the growth hormone and insulin-like growth factor-1 axis to chronic and severe calorie or protein malnutrition. J Clin Invest. 1995;95: 2258-2265.
39. Albini CH, Sotos J, Sherman B, Johanson A, Celniker A, Hopwood N, Quattrin T, Mills BJ, MacGillivray MH. Diagnostic significance of urinary growth hormone measurements in children with growth failure: correlation between serum and urine growth hormone. Pediatr Res. 1991;29:619-622.
40. Penny DG, Dunbar JC, Baylerian MS. Cardiomegaly and haemodynamics in rats with a transplantable growth hormone-secreting tumor. Cardiovasc Res. 1985;19:270-277.
41. Copeland KC, Nair KS. Recombinant human insulin-like growth factor-I increases forearm blood flow. J Clin Endocrinol Metab. 1994;79:230-232.
42. Fryburg DA. Insulin-like growth factor 1 exerts growth hormone-and insulin-like actions on human muscle protein metabolism. Am J Physiol. 1994;267:E331-E336.
43. Wu H-Y, Jeng YY, Yue C-J, Chyu K-Y, Hsueh WA, Chan TM. Endothelial-dependent vascular effects of insulin and insulin-like growth factor I in the perfused rat mesenteric artery and aortic ring. Diabetes. 1994;43:1027-1032.
44. Kiowski W, Stoschitsky K, Kim JH, Hussain MA, Froesch RE. Insulin-like growth factor-I causes endothelium-dependent arterial vasodilation. Circulation. 1994;90:1298. Abstract.
45. Cittadini A, Katz SE, Strömer H, Morgan JP, Douglas PS. Differential cardiac effects of growth hormone and IGF-1 in a new model of hormone excess in the rat: serial in vivo evaluation. Circulation. 1994;90(suppl I):I-17. Abstract.
46. Yang R, Bunting S, Gillett N, Clark R, Jin H. Growth hormone improves cardiac performance in experimental heart failure. Circulation. 1995;92:262-267.
47. Jin H, Yang R, Gillett N, Clark RG, Ko A, Paoni NF. Beneficial effects of growth hormone and insulin-like growth factor-1 in experimental heart failure in rats treated with chronic ACE inhibition. J Cardiovasc Pharmacol. 1995;26:420-425.
48. Ballard FJ, Tomas FM, Read LC, Knowles SE, Owens PC, Lemmey AB, Martin AA, Wells JRE, Wallace JC, Francis GL. Effects of IGF-1 and IGF analogs on growth during catabolic states in rats. In: Spenser EM, ed. Modern Concepts of Insulin-Like Growth Factors. New York, NY: Elsevier Science Publishing Co Inc; 1991:617-627.
49. Moore JA, Rudman CG, MacLachlan NJ, Fuller GB, Burnett B, Frane JW. Equivalent potency and pharmacokinetics of recombinant human growth hormones with or without an N-terminal methionine. Endocrinology. 1988;122:2920-2926.
50. Handelsman DJ, Spaliviero JA, Scott CD, Baxter RC. Hormonal regulation of the peripubertal surge of insulin-like growth factor-1 in the rat. Endocrinology. 1987;120:491-496.
51. Mangieri E, Croce CT, Tanzilli G, Lomurno A, Ciavolella M, Mangiaracina F, Barilla F, Campa PP. Growth hormone and insulin-like growth factor 1 in normopituitaric patients with various degrees of heart failure. Ann N Y Acad Sci. 1995;752:429-431.