-
2
-
-
0025630533
-
Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts
-
Werner Felmayer G, Werner ER, Fuchs D, Hausen A, Reibnegger G, Wachter H. Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts. J Exp Med 172:1599-1607, 1990.
-
(1990)
J Exp Med
, vol.172
, pp. 1599-1607
-
-
Werner Felmayer, G.1
Werner, E.R.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Wachter, H.6
-
3
-
-
0017839640
-
Biopterin III: Purification and characterization of enzymes involved in cerebral synthesis of 7,8-dihydrobiopterin
-
Gal EM, Nelson JM, Sherman AD. Biopterin III: Purification and characterization of enzymes involved in cerebral synthesis of 7,8-dihydrobiopterin. Neurochem Res 3:69-88, 1978.
-
(1978)
Neurochem Res
, vol.3
, pp. 69-88
-
-
Gal, E.M.1
Nelson, J.M.2
Sherman, A.D.3
-
4
-
-
0021891891
-
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin
-
Nichol CA, Smith GK, Duch DS. Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annu Rev Biochem 54:729-764, 1985.
-
(1985)
Annu Rev Biochem
, vol.54
, pp. 729-764
-
-
Nichol, C.A.1
Smith, G.K.2
Duch, D.S.3
-
5
-
-
0027101755
-
Tetrahydrobiopterin synthesis: An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle
-
Gross SS, Levi R. Tetrahydrobiopterin synthesis: An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J Biol Chem 267:25722-25729, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 25722-25729
-
-
Gross, S.S.1
Levi, R.2
-
6
-
-
0027298187
-
Regulation of the L-arginine-dependent and tetrahydrobiopterin-dependent biosynthesis of nitric oxide in murine macrophages
-
Schoedon G, Schneemann M, Hofer S, Guerrero L, Blau N, Schaffner A. Regulation of the L-arginine-dependent and tetrahydrobiopterin-dependent biosynthesis of nitric oxide in murine macrophages. Eur J Biochem 213:833-839, 1993.
-
(1993)
Eur J Biochem
, vol.213
, pp. 833-839
-
-
Schoedon, G.1
Schneemann, M.2
Hofer, S.3
Guerrero, L.4
Blau, N.5
Schaffner, A.6
-
7
-
-
0028231114
-
Nitric oxide production depends on preceding tetrahydrobiopterin synthesis by endothelial cells: Selective suppression of induced nitric oxide production by sepiapterin reductase inhibitors
-
Schoedon G, Blau N, Schneemann M, Flury G, Schaffner A. Nitric oxide production depends on preceding tetrahydrobiopterin synthesis by endothelial cells: Selective suppression of induced nitric oxide production by sepiapterin reductase inhibitors. Biochem Biophys Res Commun 199:504-510, 1994.
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 504-510
-
-
Schoedon, G.1
Blau, N.2
Schneemann, M.3
Flury, G.4
Schaffner, A.5
-
8
-
-
0029793534
-
Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport
-
Simmons WW, Ungureanu Longrois D, Smith GK, Smith TW, Kelly RA. Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport. J Biol Chem 271:23928-23937, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 23928-23937
-
-
Simmons, W.W.1
Ungureanu Longrois, D.2
Smith, G.K.3
Smith, T.W.4
Kelly, R.A.5
-
9
-
-
0030960334
-
Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-γ-stimulated RAW 264.7 cells by dexamethasone: Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation
-
Walker G, Pfeilschifter J, Kunz D. Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-γ-stimulated RAW 264.7 cells by dexamethasone: Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation. J Biol Chem 272:16679-16687, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 16679-16687
-
-
Walker, G.1
Pfeilschifter, J.2
Kunz, D.3
-
10
-
-
0030959693
-
Dexamethasone differentially affects interleukin 1β- And cAMP-triggered expression of GTP cyclohydrolase I in rat renal mesangial cells
-
Plüss C, Werner ER, Wachter H, Pfeilschifter J. Dexamethasone differentially affects interleukin 1β- and cAMP-triggered expression of GTP cyclohydrolase I in rat renal mesangial cells. Br J Pharmacol 122:534-538, 1997.
-
(1997)
Br J Pharmacol
, vol.122
, pp. 534-538
-
-
Plüss, C.1
Werner, E.R.2
Wachter, H.3
Pfeilschifter, J.4
-
11
-
-
0031576546
-
Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of septic shock
-
Hattori Y, Akimoto K, Nakanishi N, Kasai K. Glucocorticoid regulation of nitric oxide and tetrahydrobiopterin in a rat model of septic shock. Biochem Biophys Res Commun 240:298-303, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 298-303
-
-
Hattori, Y.1
Akimoto, K.2
Nakanishi, N.3
Kasai, K.4
-
12
-
-
0025848403
-
Brain nitric oxide synthase is a biopterin- And flavin-containing multifunctional oxido-reductase
-
Mayer B, John M, Heinzel B, Werner ER, Wachter H, Schultz G, Bohme E. Brain nitric oxide synthase is a biopterin- and flavin-containing multifunctional oxido-reductase. FEBS Lett 288:187-191, 1991.
-
(1991)
FEBS Lett
, vol.288
, pp. 187-191
-
-
Mayer, B.1
John, M.2
Heinzel, B.3
Werner, E.R.4
Wachter, H.5
Schultz, G.6
Bohme, E.7
-
13
-
-
0026746287
-
Macrophage nitric oxide synthase. Relationship between enzyme-bound tetrahydrobiopterin and synthase activity
-
Hevel JM, Marietta MA. Macrophage nitric oxide synthase. Relationship between enzyme-bound tetrahydrobiopterin and synthase activity. Biochemistry 31:7160-7165, 1992.
-
(1992)
Biochemistry
, vol.31
, pp. 7160-7165
-
-
Hevel, J.M.1
Marietta, M.A.2
-
14
-
-
0030464496
-
Tetrahydrobiopterin-free neuronal nitric oxide synthase: Evidence for two identical highly anticooperative pteridine binding sites
-
Gorren AC, List BM, Schrammel A, Pitters E, Hemmens B, Werner ER, Schmidt K, Mayer B. Tetrahydrobiopterin-free neuronal nitric oxide synthase: Evidence for two identical highly anticooperative pteridine binding sites. Biochemistry 35:16735-16745, 1996.
-
(1996)
Biochemistry
, vol.35
, pp. 16735-16745
-
-
Gorren, A.C.1
List, B.M.2
Schrammel, A.3
Pitters, E.4
Hemmens, B.5
Werner, E.R.6
Schmidt, K.7
Mayer, B.8
-
15
-
-
0030793667
-
Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase expressed in Echerichia coli: Heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino tetrahydrobiopterin
-
Mayer B, Wu C, Gorren ACF, Pfeiffer S, Schmidt K, Clark P, Stuehr DJ, Werner ER. Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase expressed in Echerichia coli: Heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino tetrahydrobiopterin. Biochemistry 36:8422-8427, 1997.
-
(1997)
Biochemistry
, vol.36
, pp. 8422-8427
-
-
Mayer, B.1
Wu, C.2
Gorren, A.C.F.3
Pfeiffer, S.4
Schmidt, K.5
Clark, P.6
Stuehr, D.J.7
Werner, E.R.8
-
16
-
-
0028986820
-
2,4-Diamino-6-hydroxypyrimidine, an inhibitor of tetrahydrobiopterin synthesis, downregulates the expression of iNOS protein and mRNA in primary murine macrophages
-
Bogdan C, Werner E, Stenger S, Wachter H, Rollinghoff M, Werner Felmayer G. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of tetrahydrobiopterin synthesis, downregulates the expression of iNOS protein and mRNA in primary murine macrophages. FEBS Lett 363:69-74, 1995.
-
(1995)
FEBS Lett
, vol.363
, pp. 69-74
-
-
Bogdan, C.1
Werner, E.2
Stenger, S.3
Wachter, H.4
Rollinghoff, M.5
Werner Felmayer, G.6
-
17
-
-
0030013332
-
Role of tetrahydrobiopterin availability in the regulation of nitric oxide synthase expression in human mesangial cells
-
Saura M, Perez Sala D, Canada FJ, Lamas S. Role of tetrahydrobiopterin availability in the regulation of nitric oxide synthase expression in human mesangial cells. J Biol Chem 271:14290-14295, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 14290-14295
-
-
Saura, M.1
Perez Sala, D.2
Canada, F.J.3
Lamas, S.4
-
18
-
-
0032481295
-
Modulation of inducible nitric oxide synthase mRNA stability by tetrahydrobiopterin in vascular smooth muscle cells
-
Linscheid P, Schaffner A, Schoedon G. Modulation of inducible nitric oxide synthase mRNA stability by tetrahydrobiopterin in vascular smooth muscle cells. Biochem Biophys Res Commun 243:137-141, 1998.
-
(1998)
Biochem Biophys Res Commun
, vol.243
, pp. 137-141
-
-
Linscheid, P.1
Schaffner, A.2
Schoedon, G.3
-
19
-
-
0031560412
-
Tetrahydrobiopterin modulates cyclooxygenase-2 expression in human mesangial cells
-
Perezsala D, Diazcazorla M, Ros J, Jimenez W, Lamas S. Tetrahydrobiopterin modulates cyclooxygenase-2 expression in human mesangial cells. Biochem Biophys Res Commun 241:7-12, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.241
, pp. 7-12
-
-
Perezsala, D.1
Diazcazorla, M.2
Ros, J.3
Jimenez, W.4
Lamas, S.5
-
20
-
-
0029991839
-
NF-κ B and GTP cyclohydrolase regulate cytokine-induced nitric oxide production by cardiac myocytes
-
Oddis CV, Finkel MS. NF-κ B and GTP cyclohydrolase regulate cytokine-induced nitric oxide production by cardiac myocytes. Am J Physiol 270:H1864-H1868, 1996.
-
(1996)
Am J Physiol
, vol.270
-
-
Oddis, C.V.1
Finkel, M.S.2
-
21
-
-
0029081021
-
Inhibition by N-acetyl-5-hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat
-
Klemm P, Hecker M, Stockhausen H, Wu CC, Thiemermann C. Inhibition by N-acetyl-5-hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat. Br J Pharmacol 115:1175-1181, 1995.
-
(1995)
Br J Pharmacol
, vol.115
, pp. 1175-1181
-
-
Klemm, P.1
Hecker, M.2
Stockhausen, H.3
Wu, C.C.4
Thiemermann, C.5
-
22
-
-
0027422132
-
Co-induction of tetrahydrobiopterin (BH4) levels and tyrosine hydroxylase activity in cultured PC12 cells
-
Anastasiadis PZ, States JC, Kuhn DM, Levine RA. Co-induction of tetrahydrobiopterin (BH4) levels and tyrosine hydroxylase activity in cultured PC12 cells. Adv Exp Med Biol 338:227-230, 1993.
-
(1993)
Adv Exp Med Biol
, vol.338
, pp. 227-230
-
-
Anastasiadis, P.Z.1
States, J.C.2
Kuhn, D.M.3
Levine, R.A.4
-
23
-
-
0029785475
-
Competition for tetrahydrobiopterin between phenylalanine hydroxylase and nitric oxide synthase in rat liver
-
Pastor CM, Williams D, Yoneyama T, Hatakeyama K, Singleton S, Naylor E, Billiar TR. Competition for tetrahydrobiopterin between phenylalanine hydroxylase and nitric oxide synthase in rat liver. J Biol Chem 271:24534-24538, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 24534-24538
-
-
Pastor, C.M.1
Williams, D.2
Yoneyama, T.3
Hatakeyama, K.4
Singleton, S.5
Naylor, E.6
Billiar, T.R.7
-
24
-
-
0029787074
-
Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP
-
Milstien S, Jaffe H, Kowlessur D, Bonner TI. Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP. J Biol Chem 271:19743-19751, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 19743-19751
-
-
Milstien, S.1
Jaffe, H.2
Kowlessur, D.3
Bonner, T.I.4
-
25
-
-
0030953855
-
GTP cyclohydrolase I feedback regulatory protein is a pentamer of identical subunits: Purification, cDNA cloning, and bacterial expression
-
Yoneyama T, Brewer JM, Hatakeyama K. GTP cyclohydrolase I feedback regulatory protein is a pentamer of identical subunits: Purification, cDNA cloning, and bacterial expression. J Biol Chem 272:9690-9696, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 9690-9696
-
-
Yoneyama, T.1
Brewer, J.M.2
Hatakeyama, K.3
-
26
-
-
0031974577
-
Localization of GTP cyclohydrolase in monoaminergic but not nitric oxide-producing cells
-
Hwang OY, Baker H, Gross S, Joh TH. Localization of GTP cyclohydrolase in monoaminergic but not nitric oxide-producing cells. Synapse 28:140-153, 1998.
-
(1998)
Synapse
, vol.28
, pp. 140-153
-
-
Hwang, O.Y.1
Baker, H.2
Gross, S.3
Joh, T.H.4
-
27
-
-
0030858525
-
Regulation of cerebellar nitric oxide production in response to prolonged in vivo hypoxia
-
Guo Y, Ward ME, Beasjours S, Mori M, Hussain SNA. Regulation of cerebellar nitric oxide production in response to prolonged in vivo hypoxia. J Neurosci Res 49:89-97, 1997.
-
(1997)
J Neurosci Res
, vol.49
, pp. 89-97
-
-
Guo, Y.1
Ward, M.E.2
Beasjours, S.3
Mori, M.4
Hussain, S.N.A.5
-
28
-
-
0028902943
-
Characterization of mouse and human GTP cyclohydrolase I genes: Mutations in patients with GTP cyclohydrolase I deficiency
-
Ichinose H, Ohye T, Matsuda Y, Hori T, Blau N, Burlina A, Rouse B, Matalon R, Fujita K, Nagatsu T. Characterization of mouse and human GTP cyclohydrolase I genes: Mutations in patients with GTP cyclohydrolase I deficiency. J Biol Chem 270:10062-10071, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 10062-10071
-
-
Ichinose, H.1
Ohye, T.2
Matsuda, Y.3
Hori, T.4
Blau, N.5
Burlina, A.6
Rouse, B.7
Matalon, R.8
Fujita, K.9
Nagatsu, T.10
-
29
-
-
0029882922
-
Cloning, sequencing and functional studies of the gene encoding human GTP cyclohydrolase I
-
Witter K, Werner T, Blusch JH, Schneider EM, Riess O, Ziegler I, Rodl W, Bacher A, Gütlich M. Cloning, sequencing and functional studies of the gene encoding human GTP cyclohydrolase I. Gene 171:285-290, 1996.
-
(1996)
Gene
, vol.171
, pp. 285-290
-
-
Witter, K.1
Werner, T.2
Blusch, J.H.3
Schneider, E.M.4
Riess, O.5
Ziegler, I.6
Rodl, W.7
Bacher, A.8
Gütlich, M.9
-
30
-
-
0027219407
-
Induction of GTP-cyclohydrolase I mRNA expression by lectin activation and γ-interferon treatment in human cells associated with the immune response
-
Schott K, Gutlich M, Ziegler I. Induction of GTP-cyclohydrolase I mRNA expression by lectin activation and γ-interferon treatment in human cells associated with the immune response. J Cell Physiol 156:12-16, 1993.
-
(1993)
J Cell Physiol
, vol.156
, pp. 12-16
-
-
Schott, K.1
Gutlich, M.2
Ziegler, I.3
-
31
-
-
0027265989
-
GTP cyclohydrolase I mRNA is induced by LPS in vascular smooth muscle: Characterization, sequence and relationship to nitric oxide synthase
-
Hattori Y, Gross SS. GTP cyclohydrolase I mRNA is induced by LPS in vascular smooth muscle: Characterization, sequence and relationship to nitric oxide synthase. Biochem Biophys Res Commun 195:435-141, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.195
, pp. 435-1141
-
-
Hattori, Y.1
Gross, S.S.2
-
32
-
-
0031984389
-
Cytokines stimulate GTP cyclohydrolase I gene expression in cultured human umbilical vein endothelial cells
-
Katusic ZS, Stelter A, Milstien S. Cytokines stimulate GTP cyclohydrolase I gene expression in cultured human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol 18:27-32, 1998.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 27-32
-
-
Katusic, Z.S.1
Stelter, A.2
Milstien, S.3
-
33
-
-
0030033785
-
Pyrrolidine dithiocarbamate inhibits immunostimulant-induced tetrahydrobiopterin synthesis in rat vascular smooth muscle
-
Hattori Y, Nakanishi N, Kasai K, Shimoda SI, Gross SS. Pyrrolidine dithiocarbamate inhibits immunostimulant-induced tetrahydrobiopterin synthesis in rat vascular smooth muscle. Eur J Pharmacol 296:107-112, 1996.
-
(1996)
Eur J Pharmacol
, vol.296
, pp. 107-112
-
-
Hattori, Y.1
Nakanishi, N.2
Kasai, K.3
Shimoda, S.I.4
Gross, S.S.5
-
34
-
-
0029111723
-
Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma
-
Nomura T, Ohtsuki M, Matsui S, Sumiichinose C, Nomura H, Hagino Y, Iwase K, Ichinose H, Fujita K, Nagatsu T. Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma. J Neural Transm Gen Sect 101:237-242, 1995.
-
(1995)
J Neural Transm Gen Sect
, vol.101
, pp. 237-242
-
-
Nomura, T.1
Ohtsuki, M.2
Matsui, S.3
Sumiichinose, C.4
Nomura, H.5
Hagino, Y.6
Iwase, K.7
Ichinose, H.8
Fujita, K.9
Nagatsu, T.10
-
35
-
-
0019860210
-
Biopterin cofactor biosynthesis: Independent regulation of GTP cyclohydrolase in adrenal medulla and cortex
-
Viveros OH, Lee CL, Abou-Donia MM, Nixon JC, Nichol CA. Biopterin cofactor biosynthesis: Independent regulation of GTP cyclohydrolase in adrenal medulla and cortex. Science 213:349-350, 1981.
-
(1981)
Science
, vol.213
, pp. 349-350
-
-
Viveros, O.H.1
Lee, C.L.2
Abou-Donia, M.M.3
Nixon, J.C.4
Nichol, C.A.5
-
36
-
-
0030766604
-
Glucocorticoids elevate GTP cyclohydrolase I mRNA levels in vivo and in PC12 cells
-
Serova L, Nanakova B, Rivkin M, Kvetnansky R, Sabban EL. Glucocorticoids elevate GTP cyclohydrolase I mRNA levels in vivo and in PC12 cells. Brain Res Mol Brain Res 48:251-258, 1997.
-
(1997)
Brain Res Mol Brain Res
, vol.48
, pp. 251-258
-
-
Serova, L.1
Nanakova, B.2
Rivkin, M.3
Kvetnansky, R.4
Sabban, E.L.5
-
37
-
-
0024308582
-
Neopterin as marker for activation of cellular immunity: Immunologic basis and clinical application
-
Wachter H, Fuchs D, Hausen A, Reibnegger G, Werner ER. Neopterin as marker for activation of cellular immunity: Immunologic basis and clinical application. Adv Clin Chem 27:81-141, 1989.
-
(1989)
Adv Clin Chem
, vol.27
, pp. 81-141
-
-
Wachter, H.1
Fuchs, D.2
Hausen, A.3
Reibnegger, G.4
Werner, E.R.5
-
38
-
-
0029559933
-
Nitric oxide formation as predictive parameter for acute graft-versus-host disease after human allogeneic bone marrow transplantation
-
Weiss G, Schwaighofer H, Herold M, Nachbaur D, Wachter H, Niederwieser D, Werner ER. Nitric oxide formation as predictive parameter for acute graft-versus-host disease after human allogeneic bone marrow transplantation. Transplantation 60:1239-1244, 1995.
-
(1995)
Transplantation
, vol.60
, pp. 1239-1244
-
-
Weiss, G.1
Schwaighofer, H.2
Herold, M.3
Nachbaur, D.4
Wachter, H.5
Niederwieser, D.6
Werner, E.R.7
-
39
-
-
0029020494
-
Serum nitrite plus nitrate in infection with human immunodeficiency virus type-1
-
Zangerle R, Fuchs D, Reibnegger G, Werner Felmayer G, Gallati H, Wachter H, Werner ER. Serum nitrite plus nitrate in infection with human immunodeficiency virus type-1. Immunobiology 193:59-70, 1995.
-
(1995)
Immunobiology
, vol.193
, pp. 59-70
-
-
Zangerle, R.1
Fuchs, D.2
Reibnegger, G.3
Werner Felmayer, G.4
Gallati, H.5
Wachter, H.6
Werner, E.R.7
-
40
-
-
0029815033
-
Increased production of nitric oxide correlates with viral load and activation of mononuclear phagocytes in HIV-infected patients
-
Groeneveld PH, Kroon FP, Nibbering PH, Bruisten SM, van Swieten P, van Furth R. Increased production of nitric oxide correlates with viral load and activation of mononuclear phagocytes in HIV-infected patients. Scand J Infect Dis 28:341-345, 1996.
-
(1996)
Scand J Infect Dis
, vol.28
, pp. 341-345
-
-
Groeneveld, P.H.1
Kroon, F.P.2
Nibbering, P.H.3
Bruisten, S.M.4
Van Swieten, P.5
Van Furth, R.6
-
41
-
-
0030255343
-
Pteridine and nitrite/nitrate formation in experimental septic and traumatic shock
-
Strohmaier W, Werner ER, Wachter H, Redl H, Schlag G. Pteridine and nitrite/nitrate formation in experimental septic and traumatic shock. Shock 6:254-258, 1996.
-
(1996)
Shock
, vol.6
, pp. 254-258
-
-
Strohmaier, W.1
Werner, E.R.2
Wachter, H.3
Redl, H.4
Schlag, G.5
-
42
-
-
0027267105
-
Induction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the rat
-
Werner Felmayer G, Prast H, Werner ER, Philippu A, Wachter H. Induction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the rat. FEBS Lett 322:223-226, 1993.
-
(1993)
FEBS Lett
, vol.322
, pp. 223-226
-
-
Werner Felmayer, G.1
Prast, H.2
Werner, E.R.3
Philippu, A.4
Wachter, H.5
-
43
-
-
0029942416
-
Inhibition of tetrahydrobiopterin synthesis reduces in vivo nitric oxide production in experimental endotoxic shock
-
Bune AJ, Brand MP, Heales SJ, Shergill JK, Cammack R, Cook HT. Inhibition of tetrahydrobiopterin synthesis reduces in vivo nitric oxide production in experimental endotoxic shock. Biochem Biophys Res Commun 220:13-19, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 13-19
-
-
Bune, A.J.1
Brand, M.P.2
Heales, S.J.3
Shergill, J.K.4
Cammack, R.5
Cook, H.T.6
-
44
-
-
0031045131
-
Co-induction of nitric oxide and tetrahydrobiopterin synthesis in the myocardium in vivo
-
Hattori Y, Hattori S, Motohashi S, Kasai K, Shimoda SI, Nakanishi N. Co-induction of nitric oxide and tetrahydrobiopterin synthesis in the myocardium in vivo. Mol Cell Biochem 166:177-181, 1997.
-
(1997)
Mol Cell Biochem
, vol.166
, pp. 177-181
-
-
Hattori, Y.1
Hattori, S.2
Motohashi, S.3
Kasai, K.4
Shimoda, S.I.5
Nakanishi, N.6
-
45
-
-
0031203481
-
Expression of nitric oxide synthases and GTP cyclohydrolase I in the ventilatory and limb muscles during endotoxemia
-
Hussain SNA, Giaid A, Eldawiri Q, Sakkal D, Hattori R, Guo Y. Expression of nitric oxide synthases and GTP cyclohydrolase I in the ventilatory and limb muscles during endotoxemia. Am J Respir Cell Mol Biol 17:173-180, 1997.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 173-180
-
-
Hussain, S.N.A.1
Giaid, A.2
Eldawiri, Q.3
Sakkal, D.4
Hattori, R.5
Guo, Y.6
-
46
-
-
0030575877
-
Effect of septicaemia on the plasma levels of biopterin and nitric oxide metabolites in rats and rabbits
-
van Amsterdam JG, van den Berg C, Zuidema J, te Biesebeek JD, Rokos H. Effect of septicaemia on the plasma levels of biopterin and nitric oxide metabolites in rats and rabbits. Biochem Pharmacol 52:1447-1451, 1996.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 1447-1451
-
-
Van Amsterdam, J.G.1
Van Den Berg, C.2
Zuidema, J.3
Te Biesebeek, J.D.4
Rokos, H.5
-
47
-
-
0029877544
-
Calcium-dependent nitric oxide synthesis is potently stimulated by tetrahydrobiopterin in human primordial placenta
-
Kukor Z, Meszaros G, Hertelendy F, Toth M. Calcium-dependent nitric oxide synthesis is potently stimulated by tetrahydrobiopterin in human primordial placenta. Placenta 17:69-73, 1996.
-
(1996)
Placenta
, vol.17
, pp. 69-73
-
-
Kukor, Z.1
Meszaros, G.2
Hertelendy, F.3
Toth, M.4
-
48
-
-
0028051741
-
Pteridine biosynthesis and nitric oxide synthase in Physarum polycephalum
-
Werner Felmayer G, Golderer G, Werner ER, Grobner P, Wachter H. Pteridine biosynthesis and nitric oxide synthase in Physarum polycephalum. Biochem J 304:105-111, 1994.
-
(1994)
Biochem J
, vol.304
, pp. 105-111
-
-
Werner Felmayer, G.1
Golderer, G.2
Werner, E.R.3
Grobner, P.4
Wachter, H.5
-
49
-
-
0024388901
-
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate: Tetrahydrobiopterin is required as a cofactor
-
Tayeh MA, Marietta MA. Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate: Tetrahydrobiopterin is required as a cofactor. J Biol Chem 264:19654-19658, 1989.
-
(1989)
J Biol Chem
, vol.264
, pp. 19654-19658
-
-
Tayeh, M.A.1
Marietta, M.A.2
-
50
-
-
0024351625
-
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages
-
Kwon NS, Nathan CF, Stuehr DJ. Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. J Biol Chem 264:20496-20501, 1989.
-
(1989)
J Biol Chem
, vol.264
, pp. 20496-20501
-
-
Kwon, N.S.1
Nathan, C.F.2
Stuehr, D.J.3
-
51
-
-
0025572626
-
2+ calmodulin-dependent nitric oxide synthase from porcine cerebellum: Cofactor-role of tetrahydrobiopterin
-
2+ calmodulin-dependent nitric oxide synthase from porcine cerebellum: Cofactor-role of tetrahydrobiopterin. FEBS Lett 277:215-219, 1990.
-
(1990)
FEBS Lett
, vol.277
, pp. 215-219
-
-
Mayer, B.1
John, M.2
Böhme, E.3
-
52
-
-
0027267693
-
New tetrahydrobiopterin-dependent systems
-
Kaufman S. New tetrahydrobiopterin-dependent systems. Annu Rev Nutr 13:261-286, 1993.
-
(1993)
Annu Rev Nutr
, vol.13
, pp. 261-286
-
-
Kaufman, S.1
-
53
-
-
0025719483
-
Role of C6 chirality of tetrahydropterin cofactor in catalysis and regulation of tyrosine and phenylalanine hydroxylases
-
Bailey SW, Dillard SB, Ayling JE. Role of C6 chirality of tetrahydropterin cofactor in catalysis and regulation of tyrosine and phenylalanine hydroxylases. Biochemistry 30:10226-10235, 1991.
-
(1991)
Biochemistry
, vol.30
, pp. 10226-10235
-
-
Bailey, S.W.1
Dillard, S.B.2
Ayling, J.E.3
-
54
-
-
0028302095
-
The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain
-
Klatt P, Schmid M, Leopold E, Schmidt K, Werner ER, Mayer B. The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain. J Biol Chem 269:13861-13866, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 13861-13866
-
-
Klatt, P.1
Schmid, M.2
Leopold, E.3
Schmidt, K.4
Werner, E.R.5
Mayer, B.6
-
55
-
-
0029827739
-
Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase
-
Werner ER, Pitters E, Schmidt K, Wachter H, Werner Felmayer G, Mayer B. Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase. Biochem J 320:193-196, 1996.
-
(1996)
Biochem J
, vol.320
, pp. 193-196
-
-
Werner, E.R.1
Pitters, E.2
Schmidt, K.3
Wachter, H.4
Werner Felmayer, G.5
Mayer, B.6
-
56
-
-
0025826860
-
Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine
-
Giovanelli J, Campos KL, Kaufman S. Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine. Proc Natl Acad Sci U S A 88:7091-7095, 1991.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 7091-7095
-
-
Giovanelli, J.1
Campos, K.L.2
Kaufman, S.3
-
57
-
-
0030009008
-
Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes
-
Xie QW, Leung M, Fuortes M, Sassa S, Nathan C. Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes. Proc Natl Acad Sci U S A 93:4891-4896, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 4891-4896
-
-
Xie, Q.W.1
Leung, M.2
Fuortes, M.3
Sassa, S.4
Nathan, C.5
-
58
-
-
0029043644
-
In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide
-
Mayer B, Werner ER. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol 351:453-463, 1995.
-
(1995)
Naunyn Schmiedebergs Arch Pharmacol
, vol.351
, pp. 453-463
-
-
Mayer, B.1
Werner, E.R.2
-
59
-
-
0027441142
-
Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme
-
Baek KJ, Thiel BA, Lucas S, Stuehr DJ. Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. J Biol Chem 268:21120-21129, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 21120-21129
-
-
Baek, K.J.1
Thiel, B.A.2
Lucas, S.3
Stuehr, D.J.4
-
60
-
-
0029125762
-
Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer
-
Klatt P, Schmidt K, Lehner D, Glatter O, Bachinger HP, Mayer B. Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer. EMBO J 14:3687-3695, 1995.
-
(1995)
EMBO J
, vol.14
, pp. 3687-3695
-
-
Klatt, P.1
Schmidt, K.2
Lehner, D.3
Glatter, O.4
Bachinger, H.P.5
Mayer, B.6
-
61
-
-
0029929385
-
Characterization of heme-deficient neuronal nitric oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin
-
Klatt P, Pfeiffer S, List BM, Lehner D, Glatter O, Bachinger HP, Werner ER, Schmidt K, Mayer B. Characterization of heme-deficient neuronal nitric oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin. J Biol Chem 271:7336-7342, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 7336-7342
-
-
Klatt, P.1
Pfeiffer, S.2
List, B.M.3
Lehner, D.4
Glatter, O.5
Bachinger, H.P.6
Werner, E.R.7
Schmidt, K.8
Mayer, B.9
-
62
-
-
0029935269
-
Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability
-
Albakri QA, Stuehr DJ. Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability. J Biol Chem 271:5414-5421, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 5414-5421
-
-
Albakri, Q.A.1
Stuehr, D.J.2
-
63
-
-
0029913323
-
Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding
-
List BM, Klatt P, Werner ER, Schmidt K, Mayer B. Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding. Biochem J 315:57-63, 1996.
-
(1996)
Biochem J
, vol.315
, pp. 57-63
-
-
List, B.M.1
Klatt, P.2
Werner, E.R.3
Schmidt, K.4
Mayer, B.5
-
64
-
-
0029008101
-
Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P-420 analogue
-
Wang J, Stuehr DJ, Rousseau DL. Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P-420 analogue. Biochemistry 34:7080-7087, 1995.
-
(1995)
Biochemistry
, vol.34
, pp. 7080-7087
-
-
Wang, J.1
Stuehr, D.J.2
Rousseau, D.L.3
-
65
-
-
0028931726
-
Prokaryotic expression of the heme- And flavin-binding domains of rat neuronal nitric oxide synthase as distinct polypeptides: Identification of the heme-binding proximal thiolate ligand as cysteine-415
-
McMillan K, Masters BSS. Prokaryotic expression of the heme- and flavin-binding domains of rat neuronal nitric oxide synthase as distinct polypeptides: Identification of the heme-binding proximal thiolate ligand as cysteine-415. Biochemistry 34:3686-3693, 1995.
-
(1995)
Biochemistry
, vol.34
, pp. 3686-3693
-
-
McMillan, K.1
Masters, B.S.S.2
-
66
-
-
0029889353
-
Endothelial nitric oxide synthase: Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation
-
Rodriguez Crespo I, Gerber NC, Ortiz de Montellano PR. Endothelial nitric oxide synthase: Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation. J Biol Chem 271:11462-11467, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 11462-11467
-
-
Rodriguez Crespo, I.1
Gerber, N.C.2
Ortiz De Montellano, P.R.3
-
67
-
-
0032571411
-
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate
-
Crane BR, Arvai AS, Ghosh DK, Wu CQ, Getzoff ED, Stuehr DJ, Tainer JA. Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science 279:2121-2126, 1998.
-
(1998)
Science
, vol.279
, pp. 2121-2126
-
-
Crane, B.R.1
Arvai, A.S.2
Ghosh, D.K.3
Wu, C.Q.4
Getzoff, E.D.5
Stuehr, D.J.6
Tainer, J.A.7
-
68
-
-
0030723329
-
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
-
Crane BR, Arvai AS, Gachhui R, Wu CQ, Ghosh DK, Getzoff ED, Stuehr DJ, Tainer JA. The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science 278:425-431, 1997.
-
(1997)
Science
, vol.278
, pp. 425-431
-
-
Crane, B.R.1
Arvai, A.S.2
Gachhui, R.3
Wu, C.Q.4
Ghosh, D.K.5
Getzoff, E.D.6
Stuehr, D.J.7
Tainer, J.A.8
-
69
-
-
0032485856
-
Formation of nitric oxide synthase-iron(II) nitrosoalkane complexes: Severe restriction of access to the iron(II) site in the presence of tetrahydrobiopterin
-
Renodon A, Boucher JL, Wu CQ, Gachhui R, Sari MA, Mansuy D, Stuehr D. Formation of nitric oxide synthase-iron(II) nitrosoalkane complexes: Severe restriction of access to the iron(II) site in the presence of tetrahydrobiopterin. Biochemistry 37:6367-6374, 1998.
-
(1998)
Biochemistry
, vol.37
, pp. 6367-6374
-
-
Renodon, A.1
Boucher, J.L.2
Wu, C.Q.3
Gachhui, R.4
Sari, M.A.5
Mansuy, D.6
Stuehr, D.7
-
70
-
-
0029618106
-
Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line:H4B promotes assembly of enzyme subunits into an active dimer
-
Tzeng E, Billiar TR, Robbins PD, Loftus M, Stuehr DJ. Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line:H4B promotes assembly of enzyme subunits into an active dimer. Proc Natl Acad Sci U S A 92:11771-11775, 1995.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11771-11775
-
-
Tzeng, E.1
Billiar, T.R.2
Robbins, P.D.3
Loftus, M.4
Stuehr, D.J.5
-
71
-
-
0029801655
-
Vascular inducible nitric oxide synthase gene therapy: Requirement for guanosine triphosphate cyclohydrolase I
-
Tzeng E, Yoneyama T, Hatakeyama K, Shears LL, Billiar TR. Vascular inducible nitric oxide synthase gene therapy: Requirement for guanosine triphosphate cyclohydrolase I. Surgery 120:315-321, 1996.
-
(1996)
Surgery
, vol.120
, pp. 315-321
-
-
Tzeng, E.1
Yoneyama, T.2
Hatakeyama, K.3
Shears, L.L.4
Billiar, T.R.5
-
72
-
-
0029034525
-
Purification to homogeneity and characterisation of rat brain recombinant nitric oxide synthase
-
Riveros Moreno V, Heffeman B, Torres B, Chubb A, Charles I, Moncada S. Purification to homogeneity and characterisation of rat brain recombinant nitric oxide synthase. Eur J Biochem 230:52-57, 1995.
-
(1995)
Eur J Biochem
, vol.230
, pp. 52-57
-
-
Riveros Moreno, V.1
Heffeman, B.2
Torres, B.3
Chubb, A.4
Charles, I.5
Moncada, S.6
-
73
-
-
0029114645
-
High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli
-
Roman LJ, Sheta EA, Martasek P, Gross SS, Liu Q, Masters BS. High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli. Proc Natl Acad Sci U S A 92:8428-8432, 1995.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8428-8432
-
-
Roman, L.J.1
Sheta, E.A.2
Martasek, P.3
Gross, S.S.4
Liu, Q.5
Masters, B.S.6
-
74
-
-
0031443418
-
Expression and function of recombinant endothelial NO synthase in coronary artery smooth muscle cells
-
Kullo IJ, Schwartz RS, Pompili VJ, Tsutsui M, Milstien S, Fitzpatrick LA, Katusic ZS, O'Brien T. Expression and function of recombinant endothelial NO synthase in coronary artery smooth muscle cells. Arterioscler Thromb Vasc Biol 17:2405-2412, 1997.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2405-2412
-
-
Kullo, I.J.1
Schwartz, R.S.2
Pompili, V.J.3
Tsutsui, M.4
Milstien, S.5
Fitzpatrick, L.A.6
Katusic, Z.S.7
O'Brien, T.8
-
75
-
-
0028897734
-
Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse
-
Brand MP, Heales SJ, Land JM, Clark JB. Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse. J Inherit Metab Dis 18:33-39, 1995.
-
(1995)
J Inherit Metab Dis
, vol.18
, pp. 33-39
-
-
Brand, M.P.1
Heales, S.J.2
Land, J.M.3
Clark, J.B.4
-
76
-
-
0030032756
-
Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase
-
Witteveen CF, Giovanelli J, Kaufman S. Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase. J Biol Chem 271:4143-4147, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 4143-4147
-
-
Witteveen, C.F.1
Giovanelli, J.2
Kaufman, S.3
-
77
-
-
0025892441
-
N ω hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine
-
Stuehr DJ, Kwon NS, Nathan CF, Griffith OW, Feldman PL, Wiseman J. N ω hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine. J Biol Chem 266:6259-6263, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 6259-6263
-
-
Stuehr, D.J.1
Kwon, N.S.2
Nathan, C.F.3
Griffith, O.W.4
Feldman, P.L.5
Wiseman, J.6
-
78
-
-
0028954590
-
Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide
-
Campos KL, Giovanelli J, Kaufman S. Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide. J Biol Chem 270:1721-1728, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 1721-1728
-
-
Campos, K.L.1
Giovanelli, J.2
Kaufman, S.3
-
79
-
-
0030687876
-
Allosteric modulation of rat brain nitric oxide synthase by the pterinsite enzyme inhibitor 4-amino tetrahydrobiopterin
-
Pfeiffer S, Gorren ACF, Pitters E, Schmidt K, Werner ER, Mayer B. Allosteric modulation of rat brain nitric oxide synthase by the pterinsite enzyme inhibitor 4-amino tetrahydrobiopterin. Biochem J 328:349-352, 1997.
-
(1997)
Biochem J
, vol.328
, pp. 349-352
-
-
Pfeiffer, S.1
Gorren, A.C.F.2
Pitters, E.3
Schmidt, K.4
Werner, E.R.5
Mayer, B.6
-
80
-
-
0032488596
-
Comparative functioning of dihydro- And tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase
-
Presta A, Siddhanta U, Wu CQ, Sennequier N, Huang LX, Abusoud HM, Erzurum S, Stuehr DJ. Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase. Biochemistry 37:298-310, 1998.
-
(1998)
Biochemistry
, vol.37
, pp. 298-310
-
-
Presta, A.1
Siddhanta, U.2
Wu, C.Q.3
Sennequier, N.4
Huang, L.X.5
Abusoud, H.M.6
Erzurum, S.7
Stuehr, D.J.8
-
81
-
-
0030859931
-
The ferrous-dioxy complex of neuronal nitric oxide synthase: Divergent effects of L-arginine and tetrahydrobiopterin on its stability
-
Abusoud HM, Gachhui R, Raushel FM, Stuehr DJ. The ferrous-dioxy complex of neuronal nitric oxide synthase: Divergent effects of L-arginine and tetrahydrobiopterin on its stability. J Biol Chem 272:17349-17353, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 17349-17353
-
-
Abusoud, H.M.1
Gachhui, R.2
Raushel, F.M.3
Stuehr, D.J.4
-
82
-
-
0032577582
-
Reaction of neuronal nitric oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin
-
Bee N, Gorren ACF, Voelker C, Mayer B, Lange R. Reaction of neuronal nitric oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin. J Biol Chem 273:13502-13508, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 13502-13508
-
-
Bee, N.1
Gorren, A.C.F.2
Voelker, C.3
Mayer, B.4
Lange, R.5
-
83
-
-
0027990370
-
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group: Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide
-
Griscavage JM, Fukuto JM, Komori Y, Ignarro LJ. Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group: Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide. J Biol Chem 269:21644-21649, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 21644-21649
-
-
Griscavage, J.M.1
Fukuto, J.M.2
Komori, Y.3
Ignarro, L.J.4
-
84
-
-
0028924952
-
Kinetics and mechanism of tetrahydrobiopterin-induced oxidation of nitric oxide
-
Mayer B, Klatt P, Werner ER, Schmidt K. Kinetics and mechanism of tetrahydrobiopterin-induced oxidation of nitric oxide. J Biol Chem 270:655-659, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 655-659
-
-
Mayer, B.1
Klatt, P.2
Werner, E.R.3
Schmidt, K.4
-
85
-
-
0032539974
-
Stopped-flow analysis of CO and NO binding to inducible nitric oxide synthase
-
Abusoud HM, Wu CQ, Ghosh DK, Stuehr DJ. Stopped-flow analysis of CO and NO binding to inducible nitric oxide synthase. Biochemistry 37:3777-3786, 1998.
-
(1998)
Biochemistry
, vol.37
, pp. 3777-3786
-
-
Abusoud, H.M.1
Wu, C.Q.2
Ghosh, D.K.3
Stuehr, D.J.4
-
86
-
-
0029558027
-
Inducible nitric oxide synthase: Identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin
-
Cho HJ, Martin E, Xie QW, Sassa S, Nathan C. Inducible nitric oxide synthase: Identification of amino acid residues essential for dimerization and binding of tetrahydrobiopterin. Proc Natl Acad Sci U S A 92:11514-11518, 1995.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11514-11518
-
-
Cho, H.J.1
Martin, E.2
Xie, Q.W.3
Sassa, S.4
Nathan, C.5
-
87
-
-
0030991070
-
Delineation of the arginine- And tetrahydrobiopterin-binding sites of neuronal nitric oxide synthase
-
Boyhan A, Smith D, Charles IG, Saqi M, Lowe PN. Delineation of the arginine- and tetrahydrobiopterin-binding sites of neuronal nitric oxide synthase. Biochem J 323:131-139, 1997.
-
(1997)
Biochem J
, vol.323
, pp. 131-139
-
-
Boyhan, A.1
Smith, D.2
Charles, I.G.3
Saqi, M.4
Lowe, P.N.5
-
88
-
-
0030758321
-
Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49-amino acid segment required for subunit dimerization and tetrahydrobiopterin binding
-
Gosh DK, Wu C, Pitters E, Moloney M, Werner ER, Mayer B, Stuehr DJ. Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49-amino acid segment required for subunit dimerization and tetrahydrobiopterin binding. Biochemistry 36:10609-10619, 1997.
-
(1997)
Biochemistry
, vol.36
, pp. 10609-10619
-
-
Gosh, D.K.1
Wu, C.2
Pitters, E.3
Moloney, M.4
Werner, E.R.5
Mayer, B.6
Stuehr, D.J.7
-
89
-
-
0031030864
-
Subunit interactions of endothelial nitric oxide synthase: Comparisons to the neuronal and inducible nitric oxide synthase isoforms
-
Venema RC, Ju H, Zou R, Ryan JW, Venema VJ. Subunit interactions of endothelial nitric oxide synthase: Comparisons to the neuronal and inducible nitric oxide synthase isoforms. J Biol Chem 272:1276-1282, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 1276-1282
-
-
Venema, R.C.1
Ju, H.2
Zou, R.3
Ryan, J.W.4
Venema, V.J.5
-
90
-
-
0026612234
-
Tetrahydrobiopterin induces vasodilation via enhancement of cGMP level
-
van Amsterdam JG, Wemer J. Tetrahydrobiopterin induces vasodilation via enhancement of cGMP level. Eur J Pharmacol 215:349-350, 1992.
-
(1992)
Eur J Pharmacol
, vol.215
, pp. 349-350
-
-
Van Amsterdam, J.G.1
Wemer, J.2
-
91
-
-
0030035889
-
Effect of tetrahydrobiopterin on endothelial function in canine middle cerebral arteries
-
Tsutsui M, Milstien S, Katusic ZS. Effect of tetrahydrobiopterin on endothelial function in canine middle cerebral arteries. Circ Res 79:336-342, 1996.
-
(1996)
Circ Res
, vol.79
, pp. 336-342
-
-
Tsutsui, M.1
Milstien, S.2
Katusic, Z.S.3
-
92
-
-
0031035203
-
Tetrahydrobiopterin, a cofactor for nitric oxide synthase, produces endothelium-dependent dilation of mouse pial arterioles
-
Rosenblum WI. Tetrahydrobiopterin, a cofactor for nitric oxide synthase, produces endothelium-dependent dilation of mouse pial arterioles. Stroke 28:186-189, 1997.
-
(1997)
Stroke
, vol.28
, pp. 186-189
-
-
Rosenblum, W.I.1
-
93
-
-
0029833673
-
Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin
-
Tiefenbacher CP, Chilian WM, Mitchell M, DeFily DV. Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin. Circulation 94:1423-1429, 1996.
-
(1996)
Circulation
, vol.94
, pp. 1423-1429
-
-
Tiefenbacher, C.P.1
Chilian, W.M.2
Mitchell, M.3
Defily, D.V.4
-
94
-
-
0028813306
-
Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
-
Cosentino F, Katusic ZS. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation 91:139-144, 1995.
-
(1995)
Circulation
, vol.91
, pp. 139-144
-
-
Cosentino, F.1
Katusic, Z.S.2
-
95
-
-
0026584089
-
2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
-
2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 281:627-630, 1992.
-
(1992)
Biochem J
, vol.281
, pp. 627-630
-
-
Heinzel, B.1
John, M.2
Klatt, P.3
Bohme, E.4
Mayer, B.5
-
96
-
-
0030948345
-
Characterization of bovine endothelial nitric oxide synthase as a homodimer with downregulated uncoupled NADPH oxidase activity: Tetrahydrobiopterin binding kinetics and role of haem in dimerization
-
List BM, Klosch B, Volker C, Gorren AC, Sessa WC, Werner ER, Kukovetz WR, Schmidt K, Mayer B. Characterization of bovine endothelial nitric oxide synthase as a homodimer with downregulated uncoupled NADPH oxidase activity: Tetrahydrobiopterin binding kinetics and role of haem in dimerization. Biochem J 323:159-165, 1997.
-
(1997)
Biochem J
, vol.323
, pp. 159-165
-
-
List, B.M.1
Klosch, B.2
Volker, C.3
Gorren, A.C.4
Sessa, W.C.5
Werner, E.R.6
Kukovetz, W.R.7
Schmidt, K.8
Mayer, B.9
-
97
-
-
0031577442
-
Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase
-
Wever RMF, Vandam T, Vanrijn HJM, Degroot F, Rabelink TJ. Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase. Biochem Biophys Res Commun 237:340-344, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.237
, pp. 340-344
-
-
Wever, R.M.F.1
Vandam, T.2
Vanrijn, H.J.M.3
Degroot, F.4
Rabelink, T.J.5
-
98
-
-
0030989642
-
Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production
-
Liochev SI, Fridovich I. Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production. Arch Biochem Biophys 337:115-120, 1997.
-
(1997)
Arch Biochem Biophys
, vol.337
, pp. 115-120
-
-
Liochev, S.I.1
Fridovich, I.2
-
99
-
-
0242502758
-
Superoxide anion formation from lucigenin: An electron spin resonance spin-trapping study
-
Vasquezvivar J, Hogg N, Pritchard KA, Martasek P, Kalyanaraman B. Superoxide anion formation from lucigenin: An electron spin resonance spin-trapping study. FEBS Lett 403:127-130, 1997.
-
(1997)
FEBS Lett
, vol.403
, pp. 127-130
-
-
Vasquezvivar, J.1
Hogg, N.2
Pritchard, K.A.3
Martasek, P.4
Kalyanaraman, B.5
-
100
-
-
0031018510
-
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
-
Stroes E, Kastelein J, Cosentino F, Erkelens W, Wever R, Koomans H, Luscher T, Rabelink T. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia. J Clin Invest 99:41-46, 1997.
-
(1997)
J Clin Invest
, vol.99
, pp. 41-46
-
-
Stroes, E.1
Kastelein, J.2
Cosentino, F.3
Erkelens, W.4
Wever, R.5
Koomans, H.6
Luscher, T.7
Rabelink, T.8
-
101
-
-
23444436348
-
Role of superoxide anions in the mediation of endothelium-dependent contractions
-
Cosentino F, Sill JC, Katusic ZS. Role of superoxide anions in the mediation of endothelium-dependent contractions. Hypertension 23:229-235, 1994.
-
(1994)
Hypertension
, vol.23
, pp. 229-235
-
-
Cosentino, F.1
Sill, J.C.2
Katusic, Z.S.3
-
102
-
-
0029888592
-
The role of nitric oxide in the cardiac effects of hydrogen peroxide
-
Valen G, Skjelbakken T, Vaage J. The role of nitric oxide in the cardiac effects of hydrogen peroxide. Mol Cell Biochem 159:7-14, 1996.
-
(1996)
Mol Cell Biochem
, vol.159
, pp. 7-14
-
-
Valen, G.1
Skjelbakken, T.2
Vaage, J.3
-
103
-
-
0029963107
-
2+ channels in neurons of rat dorsal motor nucleus of the vagus
-
2+ channels in neurons of rat dorsal motor nucleus of the vagus. Biochem Biophys Res Commun 221:181-185, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 181-185
-
-
Shiraki, T.1
Koshimura, K.2
Kobayashi, S.3
Miwa, S.4
Masaki, T.5
Watanabe, Y.6
Murakami, Y.7
Kato, Y.8
-
104
-
-
0000921940
-
Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats
-
Cosentino F, Patton S, Duscio LV, Werner ER, Wernerfelmayer G, Moreau P, Malinski T, Luscher TF. Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats. J Clin Invest 101:1530-1537, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 1530-1537
-
-
Cosentino, F.1
Patton, S.2
Duscio, L.V.3
Werner, E.R.4
Wernerfelmayer, G.5
Moreau, P.6
Malinski, T.7
Luscher, T.F.8
-
105
-
-
0032570254
-
5-Methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia
-
Verhaar MC, Wever RMF, Kastelein JJP, Vandam T, Koomans HA, Rabelink TJ. 5-Methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia. Circulation 97:237-241, 1998.
-
(1998)
Circulation
, vol.97
, pp. 237-241
-
-
Verhaar, M.C.1
Wever, R.M.F.2
Kastelein, J.J.P.3
Vandam, T.4
Koomans, H.A.5
Rabelink, T.J.6
-
106
-
-
0032477685
-
Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure
-
Hornig B, Arakawa N, Kohler C, Drexler H. Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure. Circulation 97:363-368, 1998.
-
(1998)
Circulation
, vol.97
, pp. 363-368
-
-
Hornig, B.1
Arakawa, N.2
Kohler, C.3
Drexler, H.4
-
107
-
-
0029133481
-
Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
-
Pritchard KAJ, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P, Wolin MS, Stemerman MB. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res 77:510-518, 1995.
-
(1995)
Circ Res
, vol.77
, pp. 510-518
-
-
Pritchard, K.A.J.1
Groszek, L.2
Smalley, D.M.3
Sessa, W.C.4
Wu, M.5
Villalon, P.6
Wolin, M.S.7
Stemerman, M.B.8
-
108
-
-
0024317795
-
Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by γ-interferon
-
Werner ER, Werner Felmayer G, Fuchs D, Hausen A, Reibnegger G, Wachter H. Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by γ-interferon. Biochem J 262:861-866, 1989.
-
(1989)
Biochem J
, vol.262
, pp. 861-866
-
-
Werner, E.R.1
Werner Felmayer, G.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Wachter, H.6
-
109
-
-
0026625694
-
Different lymphoid cell populations produce varied levels of neopterin, beta 2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, γ-interferon or tumour necrosis factor-á
-
Hofmann B, Bass H, Nishanian P, Faisal M, Figlin RA, Sarna GP, Fahey JL. Different lymphoid cell populations produce varied levels of neopterin, beta 2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, γ-interferon or tumour necrosis factor-á. Clin Exp Immunol 88:548-554, 1992.
-
(1992)
Clin Exp Immunol
, vol.88
, pp. 548-554
-
-
Hofmann, B.1
Bass, H.2
Nishanian, P.3
Faisal, M.4
Figlin, R.A.5
Sarna, G.P.6
Fahey, J.L.7
-
110
-
-
0027459585
-
Pteridine biosynthesis in human endothelial cells: Impact on nitric oxide-mediated formation of cyclic GMP
-
Werner Felmayer G, Werner ER, Fuchs D, Hausen A, Reibnegger G, Schmidt K, Weiss G, Wachter H. Pteridine biosynthesis in human endothelial cells: Impact on nitric oxide-mediated formation of cyclic GMP. J Biol Chem 268:1842-1846, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 1842-1846
-
-
Werner Felmayer, G.1
Werner, E.R.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Schmidt, K.6
Weiss, G.7
Wachter, H.8
-
111
-
-
0028196891
-
Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity
-
Rosenkranz Weiss P, Sessa WC, Milstien S, Kaufman S, Watson CA, Pober JS. Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity. J Clin Invest 93:2236-2243, 1994.
-
(1994)
J Clin Invest
, vol.93
, pp. 2236-2243
-
-
Rosenkranz Weiss, P.1
Sessa, W.C.2
Milstien, S.3
Kaufman, S.4
Watson, C.A.5
Pober, J.S.6
-
112
-
-
0027424890
-
Modulation of human endothelial cell tetrahydrobiopterin synthesis by activating and deactivating cytokines. New perspectives on endothelium-derived relaxing factor
-
Schoedon G, Schneemann M, Blau N, Edgell CJ, Schaffner A. Modulation of human endothelial cell tetrahydrobiopterin synthesis by activating and deactivating cytokines. New perspectives on endothelium-derived relaxing factor. Biochem Biophys Res Commun 196:1343-1348, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 1343-1348
-
-
Schoedon, G.1
Schneemann, M.2
Blau, N.3
Edgell, C.J.4
Schaffner, A.5
-
113
-
-
0025236440
-
Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells: GTP-cyclohydrolase I is stimulated by γ-interferon, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present
-
Werner ER, Werner Felmayer G, Fuchs D, Hausen A, Reibnegger G, Yim JJ, Pfleiderer W, Wachter H. Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells: GTP-cyclohydrolase I is stimulated by γ-interferon, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present. J Biol Chem 265:3189-3192, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 3189-3192
-
-
Werner, E.R.1
Werner Felmayer, G.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Yim, J.J.6
Pfleiderer, W.7
Wachter, H.8
-
114
-
-
0025701095
-
Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of γ-interferon and interleukin-2
-
Ziegler I, Schott K, Lubbert M, Herrmann F, Schwulera U, Bacher A. Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of γ-interferon and interleukin-2. J Biol Chem 265:17026-17030, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 17026-17030
-
-
Ziegler, I.1
Schott, K.2
Lubbert, M.3
Herrmann, F.4
Schwulera, U.5
Bacher, A.6
-
115
-
-
0027048701
-
Species and tissue specificity of mammalian GTP cyclohydrolase-I messenger RNA
-
Gütlich M, Schott K, Werner T, Bacher A, Ziegler I. Species and tissue specificity of mammalian GTP cyclohydrolase-I messenger RNA. Biochim Biophys Acta 1171:133-140, 1992.
-
(1992)
Biochim Biophys Acta
, vol.1171
, pp. 133-140
-
-
Gütlich, M.1
Schott, K.2
Werner, T.3
Bacher, A.4
Ziegler, I.5
-
116
-
-
0021264311
-
Immune response-associated production of neopterin: Release from macrophages primarily under control of γ-interferon
-
Huber C, Batchelor JR, Fuchs D, Hausen A, Lang A, Niederwieser D, Reibnegger G, Swetly P, Troppmair J, Wachter H. Immune response-associated production of neopterin: Release from macrophages primarily under control of γ-interferon. J Exp Med 160:310-316, 1984.
-
(1984)
J Exp Med
, vol.160
, pp. 310-316
-
-
Huber, C.1
Batchelor, J.R.2
Fuchs, D.3
Hausen, A.4
Lang, A.5
Niederwieser, D.6
Reibnegger, G.7
Swetly, P.8
Troppmair, J.9
Wachter, H.10
-
117
-
-
0022909292
-
γ-Interferon enhances biosynthesis of pterins in peripheral blood mononuclear cells by induction of GTP-cyclohydrolase I activity
-
Schoedon G, Troppmair J, Adolf G, Huber C, Niederwieser A. γ-Interferon enhances biosynthesis of pterins in peripheral blood mononuclear cells by induction of GTP-cyclohydrolase I activity. J Interferon Res 6:697-703, 1986.
-
(1986)
J Interferon Res
, vol.6
, pp. 697-703
-
-
Schoedon, G.1
Troppmair, J.2
Adolf, G.3
Huber, C.4
Niederwieser, A.5
-
118
-
-
0024269609
-
In vitro and in vivo studies on the induction of neopterin biosynthesis by cytokines, alloantigens and lipopolysaccharide (LPS)
-
Troppmair J, Nachbaur K, Herold M, Aulitzky W, Tilg H, Gastl G, Bieling P, Kotlan B, Flener R, Mull B, Rokos H, Huber C. In vitro and in vivo studies on the induction of neopterin biosynthesis by cytokines, alloantigens and lipopolysaccharide (LPS). Clin Exp Immunol 74:392-397, 1988.
-
(1988)
Clin Exp Immunol
, vol.74
, pp. 392-397
-
-
Troppmair, J.1
Nachbaur, K.2
Herold, M.3
Aulitzky, W.4
Tilg, H.5
Gastl, G.6
Bieling, P.7
Kotlan, B.8
Flener, R.9
Mull, B.10
Rokos, H.11
Huber, C.12
-
119
-
-
0024460738
-
Tumour necrosis factor-α and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells
-
Werner Felmayer G, Werner ER, Fuchs D, Hausen A, Reibnegger G, Wachter H. Tumour necrosis factor-α and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells. Biol Chem Hoppe Seyler 370:1063-1069, 1989.
-
(1989)
Biol Chem Hoppe Seyler
, vol.370
, pp. 1063-1069
-
-
Werner Felmayer, G.1
Werner, E.R.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Wachter, H.6
-
120
-
-
0020658974
-
Pteridines as a new marker to detect human T cells activated by allogeneic or modified self major histocompatibility complex (MHC) determinants
-
Huber C, Fuchs D, Hausen A, Margreiter R, Reibnegger G, Spielberger M, Wachter H. Pteridines as a new marker to detect human T cells activated by allogeneic or modified self major histocompatibility complex (MHC) determinants. J Immunol 130:1047-1050, 1983.
-
(1983)
J Immunol
, vol.130
, pp. 1047-1050
-
-
Huber, C.1
Fuchs, D.2
Hausen, A.3
Margreiter, R.4
Reibnegger, G.5
Spielberger, M.6
Wachter, H.7
-
121
-
-
0022402082
-
Synthesis and γ-interferon-controlled release of pteridines during activation of human peripheral blood mononuclear cells
-
Ziegler I. Synthesis and γ-interferon-controlled release of pteridines during activation of human peripheral blood mononuclear cells. Biochem Biophys Res Commun 132:404-411, 1985.
-
(1985)
Biochem Biophys Res Commun
, vol.132
, pp. 404-411
-
-
Ziegler, I.1
-
122
-
-
0023022209
-
Pteridines are produced during interleukin 2-induced T-cell proliferation and modulate transmission of this signal
-
Ziegler I, Schwulera U, Ellwart J. Pteridines are produced during interleukin 2-induced T-cell proliferation and modulate transmission of this signal. Exp Cell Res 167:531-538, 1986.
-
(1986)
Exp Cell Res
, vol.167
, pp. 531-538
-
-
Ziegler, I.1
Schwulera, U.2
Ellwart, J.3
-
123
-
-
0021837467
-
Increase of GTP cyclohydrolase I activity in mononuclear blood cells by stimulation: Detection of heterozygotes of GTP cyclohydrolase I deficiency
-
Blau N, Joller P, Atares M, Cardesa-Garcia J, Niederwieser A. Increase of GTP cyclohydrolase I activity in mononuclear blood cells by stimulation: Detection of heterozygotes of GTP cyclohydrolase I deficiency. Clin Chim Acta 148:47-52, 1985.
-
(1985)
Clin Chim Acta
, vol.148
, pp. 47-52
-
-
Blau, N.1
Joller, P.2
Atares, M.3
Cardesa-Garcia, J.4
Niederwieser, A.5
-
124
-
-
0027500347
-
2+/calmodulin-dependent nitric oxide synthase activity in the human cervix carcinoma cell line ME-180
-
2+/calmodulin-dependent nitric oxide synthase activity in the human cervix carcinoma cell line ME-180. Biochem J 289:357-361, 1993.
-
(1993)
Biochem J
, vol.289
, pp. 357-361
-
-
Werner Felmayer, G.1
Werner, E.R.2
Fuchs, D.3
Hausen, A.4
Mayer, B.5
Reibnegger, G.6
Weiss, G.7
Wachter, H.8
-
125
-
-
0031889756
-
Induction of tetrahydrobiopterin synthesis in human umbilical vein smooth muscle cells by inflammatory stimuli
-
Walter R, Linscheid P, Blau N, Kierat L, Schaffner A, Schoedon G. Induction of tetrahydrobiopterin synthesis in human umbilical vein smooth muscle cells by inflammatory stimuli. Immunol Lett 60:13-17, 1998.
-
(1998)
Immunol Lett
, vol.60
, pp. 13-17
-
-
Walter, R.1
Linscheid, P.2
Blau, N.3
Kierat, L.4
Schaffner, A.5
Schoedon, G.6
-
126
-
-
0029122719
-
Regulation of inducible nitric oxide production by cytokines in human thyrocytes in culture
-
Kasai K, Hattori Y, Nakanishi N, Manaka K, Banba N, Motohashi S, Shimoda S. Regulation of inducible nitric oxide production by cytokines in human thyrocytes in culture. Endocrinology 136:4261-4270, 1995.
-
(1995)
Endocrinology
, vol.136
, pp. 4261-4270
-
-
Kasai, K.1
Hattori, Y.2
Nakanishi, N.3
Manaka, K.4
Banba, N.5
Motohashi, S.6
Shimoda, S.7
-
127
-
-
0025328972
-
Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1)
-
Werner-Felmayer G, Werner ER, Fuchs D, Hausen A, Reibnegger G, Wachter H. Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1). Cancer Res 50:2863-2867, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 2863-2867
-
-
Werner-Felmayer, G.1
Werner, E.R.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Wachter, H.6
-
128
-
-
0029115029
-
Parallel induction of nitric oxide and tetrahydrobiopterin synthesis by cytokines in rat glial cells
-
Sakai N, Kaufman S, Milstien S. Parallel induction of nitric oxide and tetrahydrobiopterin synthesis by cytokines in rat glial cells. J Neurochem 65:895-902, 1995.
-
(1995)
J Neurochem
, vol.65
, pp. 895-902
-
-
Sakai, N.1
Kaufman, S.2
Milstien, S.3
-
129
-
-
0026321796
-
Impact of tumour necrosis factor-α and γ-interferon on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages
-
Werner ER, Werner Felmayer G, Fuchs D, Hausen A, Reibnegger G, Yim JJ, Wachter H. Impact of tumour necrosis factor-α and γ-interferon on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages. Biochem J 280:709-714, 1991.
-
(1991)
Biochem J
, vol.280
, pp. 709-714
-
-
Werner, E.R.1
Werner Felmayer, G.2
Fuchs, D.3
Hausen, A.4
Reibnegger, G.5
Yim, J.J.6
Wachter, H.7
-
130
-
-
0029084996
-
Effects of cyclosporin a and FK506 on nitric oxide and tetrahydrobiopterin synthesis in bacterial lipopolysaccharide-treated J774 macrophages
-
Hattori Y, Nakanishi N. Effects of cyclosporin A and FK506 on nitric oxide and tetrahydrobiopterin synthesis in bacterial lipopolysaccharide-treated J774 macrophages. Cell Immunol 165:7-11, 1995.
-
(1995)
Cell Immunol
, vol.165
, pp. 7-11
-
-
Hattori, Y.1
Nakanishi, N.2
-
131
-
-
0023655520
-
Biosynthesis and metabolism of pterins in peripheral blood mononuclear cells and leukemia lines of man and mouse
-
Schoedon G, Troppmair J, Fontana A, Huber C, Curtius HC, Niederwieser A. Biosynthesis and metabolism of pterins in peripheral blood mononuclear cells and leukemia lines of man and mouse. Eur J Biochem 166:303-310, 1987.
-
(1987)
Eur J Biochem
, vol.166
, pp. 303-310
-
-
Schoedon, G.1
Troppmair, J.2
Fontana, A.3
Huber, C.4
Curtius, H.C.5
Niederwieser, A.6
-
132
-
-
0030581115
-
Dissociated release of tetrahydrobiopterin and nitric oxide by lipopolysaccharide from mouse neuroblastoma cells
-
Yoshida S, Ota A, Umezawa K, Nagatsu T. Dissociated release of tetrahydrobiopterin and nitric oxide by lipopolysaccharide from mouse neuroblastoma cells. Neurosci Lett 212:135-138, 1996.
-
(1996)
Neurosci Lett
, vol.212
, pp. 135-138
-
-
Yoshida, S.1
Ota, A.2
Umezawa, K.3
Nagatsu, T.4
-
133
-
-
0027514666
-
Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line (RAW 264)
-
Sakai N, Kaufman S, Milstein S. Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line (RAW 264). Mol Pharmacol 43:6-10, 1993.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 6-10
-
-
Sakai, N.1
Kaufman, S.2
Milstein, S.3
-
134
-
-
0030571015
-
Tetrahydrobiopterin biosynthesis in C6 glioma cells. Induction of GTP cyclohydrolase I gene expression by lipopolysaccharide and cytokine treatment
-
D'Sa C, Hirayama K, West A, Hahn M, Zhu M, Kapatos G. Tetrahydrobiopterin biosynthesis in C6 glioma cells. Induction of GTP cyclohydrolase I gene expression by lipopolysaccharide and cytokine treatment. Brain Res Mol Brain Res 41:105-110, 1996.
-
(1996)
Brain Res Mol Brain Res
, vol.41
, pp. 105-110
-
-
D'Sa, C.1
Hirayama, K.2
West, A.3
Hahn, M.4
Zhu, M.5
Kapatos, G.6
-
135
-
-
0031014552
-
Induction of guanosine triphosphate-cyclohydrolase by follicle-stimulating hormone enhances interleukin-1 β-stimulated nitric oxide synthase activity in granulosa cells
-
Tabraue C, Diaz Penate R, Gallardo G, Hernandez I, Quintana J, Lopez Blanco F, Gonzalez Reyes J, Fanjul LF, Ruiz de Galarreta CM. Induction of guanosine triphosphate-cyclohydrolase by follicle-stimulating hormone enhances interleukin-1 β-stimulated nitric oxide synthase activity in granulosa cells. Endocrinology 138:162-168, 1997.
-
(1997)
Endocrinology
, vol.138
, pp. 162-168
-
-
Tabraue, C.1
Diaz Penate, R.2
Gallardo, G.3
Hernandez, I.4
Quintana, J.5
Lopez Blanco, F.6
Gonzalez Reyes, J.7
Fanjul, L.F.8
Ruiz De Galarreta, C.M.9
-
136
-
-
0027440763
-
Inducible nitric oxide synthase activity in hepatocytes is dependent on the coinduction of tetrahydrobiopterin synthesis
-
Di Silvio M, Geller DA, Gross SS, Nussler A, Freeswick P, Simmons RL, Billiar TR. Inducible nitric oxide synthase activity in hepatocytes is dependent on the coinduction of tetrahydrobiopterin synthesis. Adv Exp Med Biol 338:305-308, 1993.
-
(1993)
Adv Exp Med Biol
, vol.338
, pp. 305-308
-
-
Di Silvio, M.1
Geller, D.A.2
Gross, S.S.3
Nussler, A.4
Freeswick, P.5
Simmons, R.L.6
Billiar, T.R.7
-
137
-
-
0028037534
-
Tetrahydrobiopterin is a limiting factor of nitric oxide generation in interleukin-1 β-stimulated rat glomerular mesangial cells
-
Mühl H, Pfeilschifter J. Tetrahydrobiopterin is a limiting factor of nitric oxide generation in interleukin-1 β-stimulated rat glomerular mesangial cells. Kidney Int 46:1302-1306, 1994.
-
(1994)
Kidney Int
, vol.46
, pp. 1302-1306
-
-
Mühl, H.1
Pfeilschifter, J.2
-
138
-
-
0029813024
-
Interleukin-1β and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells
-
Plüss C, Werner ER, Blau N, Wachter H, Pfeilschifter J. Interleukin-1β and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells. Biochem J 318:665-671, 1996.
-
(1996)
Biochem J
, vol.318
, pp. 665-671
-
-
Plüss, C.1
Werner, E.R.2
Blau, N.3
Wachter, H.4
Pfeilschifter, J.5
-
139
-
-
0029825111
-
Endothelin-1 inhibits induction of nitric oxide synthase and GTP cyclohydrolase I in rat mesangial cells
-
Hirahashi J, Nakaki T, Hishikawa K, Marumo T, Yasumori T, Hayashi M, Suzuki H, Saruta T. Endothelin-1 inhibits induction of nitric oxide synthase and GTP cyclohydrolase I in rat mesangial cells. Pharmacology 53:241-249, 1996.
-
(1996)
Pharmacology
, vol.53
, pp. 241-249
-
-
Hirahashi, J.1
Nakaki, T.2
Hishikawa, K.3
Marumo, T.4
Yasumori, T.5
Hayashi, M.6
Suzuki, H.7
Saruta, T.8
-
140
-
-
0029929256
-
Regulation of tyrosine hydroxylase and tetrahydrobiopterin biosynthetic enzymes in PC12 cells by NGF, EGF, and IFN-γ
-
Anastasiadis PZ, Kuhn DM, Blitz J, Imerman BA, Louie MC, Levine RA. Regulation of tyrosine hydroxylase and tetrahydrobiopterin biosynthetic enzymes in PC12 cells by NGF, EGF, and IFN-γ. Brain Res 713:125-133, 1996.
-
(1996)
Brain Res
, vol.713
, pp. 125-133
-
-
Anastasiadis, P.Z.1
Kuhn, D.M.2
Blitz, J.3
Imerman, B.A.4
Louie, M.C.5
Levine, R.A.6
-
141
-
-
0027490483
-
Growth factor regulation of interleukin-1 β-induced nitric oxide synthase and GTP: Cyclohydrolase expression in cultured smooth muscle cells
-
Scott Burden T, Elizondo E, Ge T, Boulanger CM, Vanhoutte PM. Growth factor regulation of interleukin-1 β-induced nitric oxide synthase and GTP: Cyclohydrolase expression in cultured smooth muscle cells. Biochem Biophys Res Commun 196:1261-1266, 1993.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 1261-1266
-
-
Scott Burden, T.1
Elizondo, E.2
Ge, T.3
Boulanger, C.M.4
Vanhoutte, P.M.5
-
142
-
-
0030498021
-
Effects of activating and deactivating cytokines on the functionally linked tetrahydrobiopterin: No pathways in vascular smooth muscle cells
-
Walter R, Blau N, Kierat L, Schaffner A, Schoedon G. Effects of activating and deactivating cytokines on the functionally linked tetrahydrobiopterin: No pathways in vascular smooth muscle cells. Immunol Lett 54:25-29, 1996.
-
(1996)
Immunol Lett
, vol.54
, pp. 25-29
-
-
Walter, R.1
Blau, N.2
Kierat, L.3
Schaffner, A.4
Schoedon, G.5
-
143
-
-
0031921295
-
Induction of nitric oxide and tetrahydrobiopterin synthesis by lipoteichoic acid from Staphylococcus aureus in vascular smooth muscle cells
-
Hattori Y, Kasai K, Nakanishi N, Gross SS, Thiemermann C. Induction of nitric oxide and tetrahydrobiopterin synthesis by lipoteichoic acid from Staphylococcus aureus in vascular smooth muscle cells. J Vasc Res 35:104-108, 1998.
-
(1998)
J Vasc Res
, vol.35
, pp. 104-108
-
-
Hattori, Y.1
Kasai, K.2
Nakanishi, N.3
Gross, S.S.4
Thiemermann, C.5
-
144
-
-
0029997003
-
Regulation of GTP cyclohydrolase I gene expression and tetrahydrobiopterin content in cultured sympathetic neurons by leukemia inhibitory factor and ciliary neurotrophic factor
-
Stegenga SL, Hirayama K, Kapatos G. Regulation of GTP cyclohydrolase I gene expression and tetrahydrobiopterin content in cultured sympathetic neurons by leukemia inhibitory factor and ciliary neurotrophic factor. J Neurochem 66:2541-2545, 1996.
-
(1996)
J Neurochem
, vol.66
, pp. 2541-2545
-
-
Stegenga, S.L.1
Hirayama, K.2
Kapatos, G.3
-
145
-
-
0028179435
-
2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages
-
Sung YJ, Hotchkiss JH, Dietert RR. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages. Int J Immunopharmacol 16:101-108, 1994.
-
(1994)
Int J Immunopharmacol
, vol.16
, pp. 101-108
-
-
Sung, Y.J.1
Hotchkiss, J.H.2
Dietert, R.R.3
-
146
-
-
0030836060
-
Coordinate induction of tetrahydrobiopterin synthesis and nitric oxide synthase activity in chicken macrophages: Upregulation of GTP cyclohydrolase I activity
-
Kaspers B, Gutlich M, Witter K, Losch U, Goldberg M, Ziegler I. Coordinate induction of tetrahydrobiopterin synthesis and nitric oxide synthase activity in chicken macrophages: Upregulation of GTP cyclohydrolase I activity. Comp Biochem Physiol [B] 117:209-215, 1997.
-
(1997)
Comp Biochem Physiol [B]
, vol.117
, pp. 209-215
-
-
Kaspers, B.1
Gutlich, M.2
Witter, K.3
Losch, U.4
Goldberg, M.5
Ziegler, I.6
-
147
-
-
0025943425
-
Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent, and inhibited by arginine analogs with a rank order of potency characteristic of activated macrophages
-
Gross SS, Jaffe EA, Levi R, Kilbourn RG. Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent, and inhibited by arginine analogs with a rank order of potency characteristic of activated macrophages. Biochem Biophys Res Commun 178:823-829, 1991.
-
(1991)
Biochem Biophys Res Commun
, vol.178
, pp. 823-829
-
-
Gross, S.S.1
Jaffe, E.A.2
Levi, R.3
Kilbourn, R.G.4
-
148
-
-
0029008745
-
Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules
-
Amoah Apraku B, Tang SS, Ingelfinger JR, Guzman NJ. Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules. J Am Soc Nephrol 5:1630-1633, 1995.
-
(1995)
J Am Soc Nephrol
, vol.5
, pp. 1630-1633
-
-
Amoah Apraku, B.1
Tang, S.S.2
Ingelfinger, J.R.3
Guzman, N.J.4
-
149
-
-
0026556496
-
Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells
-
Schmidt K, Werner ER, Mayer B, Wachter H, Kukovetz WR. Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells. Biochem J 281:297-300, 1992.
-
(1992)
Biochem J
, vol.281
, pp. 297-300
-
-
Schmidt, K.1
Werner, E.R.2
Mayer, B.3
Wachter, H.4
Kukovetz, W.R.5
-
150
-
-
0027221653
-
Nitric oxide synthase induction in glial cells: Effect on neuronal survival
-
Demerle Pallardy C, Lonchampt MO, Chabrier PE, Braquet P. Nitric oxide synthase induction in glial cells: Effect on neuronal survival. Life Sci 52:1883-1890, 1993.
-
(1993)
Life Sci
, vol.52
, pp. 1883-1890
-
-
Demerle Pallardy, C.1
Lonchampt, M.O.2
Chabrier, P.E.3
Braquet, P.4
-
151
-
-
0026541847
-
Synergism between interleukin-1β and γ-interferon, an inducer of nitric oxide synthase, in rat lung fibroblasts
-
Jorens PG, Van Overveld FJ, Vermeire PA, Bull H, Herman AG. Synergism between interleukin-1β and γ-interferon, an inducer of nitric oxide synthase, in rat lung fibroblasts. Eur J Pharmacol 224:7-12, 1992.
-
(1992)
Eur J Pharmacol
, vol.224
, pp. 7-12
-
-
Jorens, P.G.1
Van Overveld, F.J.2
Vermeire, P.A.3
Bull, H.4
Herman, A.G.5
-
152
-
-
19244373946
-
Tetrahydrobiopterin synthesis and inducible nitric oxide production in pulmonary artery smooth muscle
-
Nakayama DK, Geller DA, Di Silvio M, Bloomgarden G, Davies P, Pitt BR, Hatakeyama K, Kagamiyama H, Simmons RL, Billiar TR. Tetrahydrobiopterin synthesis and inducible nitric oxide production in pulmonary artery smooth muscle. Am J Physiol 266:L455-L460, 1994.
-
(1994)
Am J Physiol
, vol.266
-
-
Nakayama, D.K.1
Geller, D.A.2
Di Silvio, M.3
Bloomgarden, G.4
Davies, P.5
Pitt, B.R.6
Hatakeyama, K.7
Kagamiyama, H.8
Simmons, R.L.9
Billiar, T.R.10
-
153
-
-
0030907885
-
Cysteine-200 of human inducible nitric oxide synthase is essential for dimerization of haem domains and for binding of haem, nitroarginine, and tetrahydrobiopterin
-
Cubberley RR, Alderton WK, Boyhan A, Charles IG, Lowe PN, Old RW. Cysteine-200 of human inducible nitric oxide synthase is essential for dimerization of haem domains and for binding of haem, nitroarginine, and tetrahydrobiopterin. Biochem J 323:141-146, 1997.
-
(1997)
Biochem J
, vol.323
, pp. 141-146
-
-
Cubberley, R.R.1
Alderton, W.K.2
Boyhan, A.3
Charles, I.G.4
Lowe, P.N.5
Old, R.W.6
-
154
-
-
0028848093
-
Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity
-
Chen PF, Tsai AL, Wu KK. Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity. Biochem Biophys Res Commun 215:1119-1129, 1995.
-
(1995)
Biochem Biophys Res Commun
, vol.215
, pp. 1119-1129
-
-
Chen, P.F.1
Tsai, A.L.2
Wu, K.K.3
|