Vascular inducible nitric oxide synthase gene therapy: Requirement for guanosine triphosphate cyclohydrolase I

Surgery

Volumn 120, Issue 2, 1996, Pages 315-321

  Tzeng, E ^a   Yoneyama, T ^a   Hatakeyama, K ^a   Shears II, L L ^a   Billiar, T R ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE THERAPY; GENE TRANSFER; HUMAN; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

EID: 0029801655     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(96)80304-7     Document Type: Article

References (24)

1. Ross R The pathogenesis of atherosclerosis: a perspective for the 1990's Nature 362 1992 801 809
2. Ignarro LJ Buga GM Wood KS Byrns RE Chaudhuri G Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide Proc Natl Acad Sci USA 84 1987 9265 9269
3. Palmer RMJ Ferrige AG Moncada S Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor Nature 327 1987 524 527
4. Mellion BT Ignarro LJ Ohlstein EH Pontecarvo EG Hyman AL Kadowitz PJ Evidence for the inhibitory role of guanosine 3′:5′-monophosphate in ADP induced human platelet aggregation in the presence of nitric oxide and related vasodilators Blood 57 1981 946 955
5. Garg UC Hassid A Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells J Clin Invest 83 1989 1774 1777
6. Panza JA Quyyumi AA Brush JE Jr Epstein SE Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension N Engl J Med 323 1990 22 27
7. Chester AH O'Neil GS Moncada S Tadjkarimi S Yacoub MH Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries Lancet 336 1990 897 900
8. McNamara DB Bedi B Aurora H L-arginine inhibits balloon catheter-induced intimal hyperplasia Biochem Biophys Res Commun 193 1993 291 296
9. Davies MG Kim JH Dalen H Makhoul RG Svendsen E Hagen PO Reduction of experimental vein graft intimal hyperplasia and preservation of nitric oxide-mediated relaxation by the nitric oxide precursor L-arginine Surgery 116 1994 557 568
10. von der Leyen HE Gibbons GH Morishita R Gene therapy inhibiting neointimal vascular lesions: in vivo transfer of endothelial cell nitric oxide synthase gene Proc Natl Acad Sci USA 92 1995 1137 1141
11. Tzeng E Shears LL II Robbins PD Vascular gene transfer of the human inducible nitric oxide synthase: characterization of activity and effects on myointimal hyperplasia Molec Med 2 1996 211 225
12. 4B promotes assembly of enzyme subunits into an active dimer Proc Natl Acad Sci USA 92 1995 11771 11775
13. Gross SS Levi R Tetrahydrobiopterin synthesis: an absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle J Biol Chem 267 1992 25722 25729
14. Werner ER Werner-Felmayer G Wachter H Tetrahydrobiopterin and cytokines P S E B M 203 1993 1 12
15. Werner ER Werner-Felmayer G Fuchs D Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T24 cells: GTP cyclohydrolase I is stimulated by interferon-γ, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present J Biol Chem 265 1990 3189 3192
16. Nakayama DK Geller DA DiSilvio M Tetrahydrobiopterin synthesis and inducible nitric oxide production in pulmonary artery smooth muscle Am J Physiol 266 1994 L455 L460
17. Togari A Ichinose H Matsumoto S Fujita K Nagatsu T Multiple mRNA forms of human GTP cyclohydrolase I Biochem Biophys Res Commun 187 1992 359 365
18. Geller DA Lowenstein CJ Shapiro RA Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes Proc Natl Acad Sci USA 90 1993 3491 3495
19. Davies P Patton W Peripheral and central vascular smooth muscle cells from rat lung exhibit different cytoskeletal protein profiles but similar growth factor requirements J Cell Physiol 159 1994 399 406
20. Geller DA Nussler AK DiSilvio M Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes Proc Natl Acad Sci USA 90 1993 522 526
21. Hatakeyama K Harada T Suzuki S Watanabe Y Kagamiyama H Purification and characterization of rat liver GTP cyclohydrolase I: cooperative binding of GTP to the enzyme J Biol Chem 264 1989 21660 21664
22. Fukushima T Nixon JC Analysis of reduced forms of biopterin in biological tissues and fluids Anal Biochem 132 1983 6 13
23. Baek KJ Thiel BA Lucas S Stuehr DJ Macrophage nitric oxide synthase subunits: purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme J Biol Chem 268 1993 21120 21129
24. Kaufman S Berlow S Summer GK Hyperphenylalaninaemia due to a deficiency of biopterin: a variant of phenylketonuria N Engl J Med 299 1978 673 679