Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 20, 1996, Pages 2371-2376

  Hoekstra, William J ^a   Maryanoff, Bruce E ^a   Andrade Gordon, Patricia ^a   Cohen, Judith H ^a   Costanzo, Michael J ^a   Damiano, Bruce P ^a   Haertlein, Barbara J ^a   Harris, Bruce D ^a   Kauffman, Jack A ^a   Keane, Patricia M ^a   McComsey, David F ^a   Villani Jr , Frank J ^a   Yabut, Stephen C ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [1 [3 (4 PIPERIDINYL)PROPIONYL]NIPECOTOYLAMINO]PROPIONIC ACID; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; NIPECOTIC ACID DERIVATIVE; UNCLASSIFIED DRUG; XEMILOFIBAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHIRALITY; CONTROLLED STUDY; DOG; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; ORAL DRUG ADMINISTRATION; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION;

ANIMALIA; CANIS FAMILIARIS;

EID: 0030598195     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00438-6     Document Type: Article

References (20)

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