The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor

Journal of Biological Chemistry

Volumn 271, Issue 10, 1996, Pages 5850-5858

  Pandit, Sunil D ^a   Donis Kellert, Helen ^a   Iwamoto, Takeo ^b   Tomich, John M ^b,c   Pike, Linda J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

^c Kansas State Univ Biotech Core F ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; METHIONINE; PROTEIN TYROSINE KINASE; THREONINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; ENZYME SPECIFICITY; IMMUNOREGULATION; MALIGNANT TRANSFORMATION; MOLECULAR CLONING; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTO ONCOGENE; RECEPTOR DOWN REGULATION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL DIVISION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; DNA PRIMERS; DOWN-REGULATION; DROSOPHILA PROTEINS; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE LIBRARY; HUMANS; KINETICS; MICE; MOLECULAR SEQUENCE DATA; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2B; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PHOSPHORYLATION; PLASMIDS; POINT MUTATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; PROTO-ONCOGENES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0029911731     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.10.5850     Document Type: Article

References (36)

1. Takahashi, M., Ritz. J., and Cooper, G M (1985) Cell 42, 581-588
2. Mulligan, L. M., Kwok. J. B. J., Healey, C. S., Elsdon, M. J., Eng, C., Gardner, E., Love, D., Mole, S. E., Moore, J. K., Papi, L., Ponder, M. A., Telenius, H., Tunnnacliffe, A., and Ponder, B. A. J. (1993) Nature 363, 458-460
3. Donis-Keller, H., Dou, S., Chi, D., Carlson, K. M., Toshima, K., Lairmore, T. C., Howe, J. R , Moley, J. F., Goodfellow, P., and Wells, S. A. (1993) Hum. Mol Genet. 2, 851-856
4. Carlson, K. M., Dou, S., Chi, D., Scavarda, N., Toshima, K., Jackson, C. E., Wells, S A., Goodfellow, P. J., and Donis-Keller, H. (1994) Proc. Natl. Acad. Sci U. S. A 91, 1579-1583
5. Hofstra, R. M., Landsvater, R. M., Ceccheriru, I., Stulp, R. P., Stelwagen, T., Luo, Y. P. B., Hoppener, J W. M , van Amstel, H. K P . Romeo, G., Lips. C. J. M., and Buys, C H. C. M (1994) Nature 367, 375-376
6. Eng, C., Smith, D. P., Mulligan, L. M , Nagai, M. A , Healey, C. S., Ponder, M. A., Gardner. E., Shumann, G. F. W., Jackson. C. E., Tunnacliffe, A, and Ponder, B A. J. (1994) Hum. Mol Genet. 3, 237-241
7. Takahashi, M., Buma, Y., Iwamoto, T., Inaguma, Y., Ikeda, H , and Hiai, H (1988) Oncogens 3, 571-578
8. Takahashi, M., Buma, Y., and Hiai, H. (1989) Oncogens 4, 805-806
9. Iwamoto, T., Taniguchi, M., Awai, N., Ohkusu, K., Nakashima, L, and Takahashi. M. (1993) Oncogene 8, 1087-1091
10. Bolino, A., Sehuffenecker, I., Luo, Y., Seri, M., Silengo, M., Tocco, T., Chabrier, G., Houdent, C., Murat. A, Schlumberger, M., Tourniaire. J., Lenoir, G. M., and Romeo, G. (1995) Oncogene 10, 2415-2419
11. Asai, N, Iwashita, T, Matsuyama, M., and Takahashi, M. (1995) Mol Cell. Biol 15, 1613-1619
12. Santoro, M., Cariomagno. F., Romano, A., Bottaro. D. P., Dathan, N A., Grieco, M., Fusco, A. Vecchio, G , Matoskova, B., Kraus, M. H., and DiFiore, P P. (1995) Science 267, 381-383
13. Hanks, S. K., Quinn, A. M , and Hunter, T (1988) Science 241, 42-52
14. Knighton. D. R., Zheng, J., Eyck, L F T., Ashford, V. A, and Xuong. H -H , Taylor, S. S . and Sowadski, J. M. (1991) Science 253, 407-414
15. Knighton, D. R., Zheng. J., Eyck, L. F. T., Xuong, H.-H., Taylor. S S., and Sowadski, J. M. (1991) Science 253, 414-420
16. Songyang, Z., Carraway, K. L, Eck, M. J., Harrison, S. C., Feldman, R. A., Mohammadi, M., Schlessinger, J., Hubbard. S. R.. Smith, D. P., Eng, C, Lorenzo, M J., Ponder, B. A J., Mayer, B. J , and Cantley, L. C. (1995) Nature 373, 536-539
17. Schuh, S. M., Newberry. E. P., Dalton. M. A., and Pike, L. J. (1994) Mol. Biol. Cell 5, 739-746
18. Sarin, V. K, Kent, S. B. H.. Tam, J. P, and Merrifield, R B ( 1981) Anal. Biochem. 117, 147-157
19. Sayers, J. R., Krekel, C., and Eckstein, F. (1992) BioTechniques 13, 592-596
20. Ullrich, A. Coussens, L., Hayflick, J S., Dull. T J , Gray, A., Tam, A. W., Lee, J., Yarden, Y., Libermann, T. A., Schlessinger, J., Downward, J., Mayes, E L. V., Whittle, N., Waterfield, N. D., and Seeburg, P. H (1984) Nature 309, 418-425
21. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual. Second Edition, Cold Spring Harbor Laboratory, Cold Spring Harbor. NY
22. Sachais, B. S., Snider, R. M , Lowe, J. A., and Krause, J E. (1993) J. Biol Chem 268, 2319-2323
23. Munson, P. J , and Rodbard, D (1980) Anal. Biochem 107, 220-239
24. Songyang, Z., Blechner. S., Hoagland, N , Hoekstra, M. F., Piwnica-Worms, H . and Cantley. L. C. (1994) Curr. Biol. 4, 973-982
25. Laemmli, U. K. (1970) Nature 227, 680-685
26. Auger. K R., Serunian, L. A., and Cantley, L. C. (1990) in Methods in Inositide Research (lrvine, R F , ed) pp. 159-166, Raven Press, Ltd., New York
27. Kavanaugh, W. M., and Williams, L. T. (1994) Science 266, 1862-1865
28. Downward, J., Parker, P., and Waterfield, M D (1984) Nature 311, 483-485
29. Hsuan, J J., Totty, N., and Waterfield, M. D. (1989) Biochem. J. 262, 659-663
30. Walton, G. M., Chen, W. S., Rosenfeld, M. G , and Gill. G N. (1990) J. Biol. Chem. 265, 1750-1754
31. Felder, S , Miller, K., Moehren, G., Ullrich, A., Schlessinger, J., and Hopkins, C R (1990) Cell 61, 623-634
32. Honegger, A M., Schnidt, A, Ullrich, A, and Schlessinger, J, (1990) J. Cell Biol. 110, 1541-1548
33. Yamauchi, K., Milarski, K L., Saltiel, A. R , and Pessin, J. E, (1995) Proc Nail Acad.Sci U. S. A. 92, 664-668
34. Xiao, S., Rose, D. W., Sasaoka, T., Maegawa, H., Burke, T. R., Jr., Roller. P. P., Shoelson, S E., and lefsky, J. M. (1994) J. Biol. Chem. 269, 21244-21248
35. Zheng, X. M., Wang, Y., and Pallen, C. J (1992) Nature 359, 336-339
36. Wiley, H. S , and Cunningham. D D (1982) J. Biol. Chem. 257, 4222-4229