메뉴 건너뛰기




Volumn 38, Issue 3, 1997, Pages 179-194

p53-Dependent Signal Transduction Induced by Stress

Author keywords

Apoptosis; Cancer evolution; p53; Signal transduction; Stress

Indexed keywords

BACTERIOPHAGES; CELL DEATH; CELL SIGNALING; CROSSTALK; DISEASES; MAMMALS; ONCOGENIC VIRUSES; SIGNAL TRANSDUCTION;

EID: 0031216384     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.38.179     Document Type: Article
Times cited : (61)

References (135)
  • 2
    • 0027522356 scopus 로고
    • Cell in stress: Transcriptional activation of heat shock genes
    • Morimoto, R.I. (1993) Cell in stress: transcriptional activation of heat shock genes. Science 259: 1409-1410.
    • (1993) Science , vol.259 , pp. 1409-1410
    • Morimoto, R.I.1
  • 3
    • 0030597239 scopus 로고    scopus 로고
    • Three paths to stress relief
    • Canman, C.E. and Kastan, M.B. (1996) Three paths to stress relief. Nature 384: 213-214.
    • (1996) Nature , vol.384 , pp. 213-214
    • Canman, C.E.1    Kastan, M.B.2
  • 4
  • 5
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes?
    • Lu, X. and Lane, D. (1993) Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes? Cell 75: 765-778.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.2
  • 7
    • 0023712476 scopus 로고
    • The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevsiae
    • Weinert, T.A. and Hartwell, L.H. (1988) The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevsiae. Science 241: 317-322.
    • (1988) Science , vol.241 , pp. 317-322
    • Weinert, T.A.1    Hartwell, L.H.2
  • 9
    • 15844364884 scopus 로고    scopus 로고
    • p53-dependent induction of WAF1 by heat treatment in human glioblastoma cells
    • Ohnishi, T., Wang, X., Ohnishi, K., Matsumoto, H. and Takahashi, A. (1996). p53-dependent induction of WAF1 by heat treatment in human glioblastoma cells. J. Biol. Chem. 271: 14510-14513.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14510-14513
    • Ohnishi, T.1    Wang, X.2    Ohnishi, K.3    Matsumoto, H.4    Takahashi, A.5
  • 10
    • 0030869505 scopus 로고    scopus 로고
    • p53-dependent Induction of WAF1 by Low pH Culture Condition in Human Glioblastoma Cells
    • Ohtsubo, T., Wang, X., Takahashi, A., Ohnishi, K., Saito, H. Song, C.W. and Ohnishi, T. (1997) p53-dependent Induction of WAF1 by Low pH Culture Condition in Human Glioblastoma Cells. Cancer Res. 57: 3910-3913.
    • (1997) Cancer Res. , vol.57 , pp. 3910-3913
    • Ohtsubo, T.1    Wang, X.2    Takahashi, A.3    Ohnishi, K.4    Saito, H.5    Song, C.W.6    Ohnishi, T.7
  • 11
    • 0029027583 scopus 로고
    • Nuclear accumulation of p53 in normal human fibroblasts is induced by various cellular stresses which evoke the heat shock response independent of cell cycle
    • Sugano, T., Nitta, M., Ohmori, H. and Yamaizumi, M. (1995) Nuclear accumulation of p53 in normal human fibroblasts is induced by various cellular stresses which evoke the heat shock response independent of cell cycle. Jpn. J. Cancer Res. 86: 415-418.
    • (1995) Jpn. J. Cancer Res. , vol.86 , pp. 415-418
    • Sugano, T.1    Nitta, M.2    Ohmori, H.3    Yamaizumi, M.4
  • 12
    • 0027358857 scopus 로고
    • Inhibition of DNA replication factor RPA by p53
    • Dutta, A., Ruppert, J., Aster, J. and Winchester, H. (1993) Inhibition of DNA replication factor RPA by p53. Nature 365: 79-82.
    • (1993) Nature , vol.365 , pp. 79-82
    • Dutta, A.1    Ruppert, J.2    Aster, J.3    Winchester, H.4
  • 13
    • 0026523614 scopus 로고
    • Binding of a 95kD protein is correlated with wild-type p53 activity
    • Barak, Y. and Oren, M. (1992) Binding of a 95kD protein is correlated with wild-type p53 activity. EMBO J. 11: 2115-2121.
    • (1992) EMBO J. , vol.11 , pp. 2115-2121
    • Barak, Y.1    Oren, M.2
  • 14
    • 0024271276 scopus 로고
    • Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsp73 in human osteosarcoma cell lines
    • Ehrhart, J.C., Duthu, A., Ullrich, S., Appella, E. and May, P. (1988) Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsp73 in human osteosarcoma cell lines. Oncogene 3: 595-603.
    • (1988) Oncogene , vol.3 , pp. 595-603
    • Ehrhart, J.C.1    Duthu, A.2    Ullrich, S.3    Appella, E.4    May, P.5
  • 16
    • 0027446860 scopus 로고
    • Direct interaction between the transcriptional activation domain of human p53 and the TATA-box-binding protein
    • Truant, R., Xiao, H., Ingles, C.J. and Greenblatt, J. (1993) Direct interaction between the transcriptional activation domain of human p53 and the TATA-box-binding protein. J. Biol. Chem. 268: 2284-2287.
    • (1993) J. Biol. Chem. , vol.268 , pp. 2284-2287
    • Truant, R.1    Xiao, H.2    Ingles, C.J.3    Greenblatt, J.4
  • 18
    • 0029164446 scopus 로고
    • The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis
    • Maheswaran, S., Englert, C., Bennet, P., Heinrich, G. and Haeber, D.A. (1995) The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis. Genes & Dev. 9: 2143-2156.
    • (1995) Genes & Dev. , vol.9 , pp. 2143-2156
    • Maheswaran, S.1    Englert, C.2    Bennet, P.3    Heinrich, G.4    Haeber, D.A.5
  • 20
    • 0029969418 scopus 로고    scopus 로고
    • p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction
    • Sturzbecher, H., Donzelmann, B., Henning, W., Knippschild, U. and Buchhop, S. (1996) p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO J. 15: 1992-2002.
    • (1996) EMBO J. , vol.15 , pp. 1992-2002
    • Sturzbecher, H.1    Donzelmann, B.2    Henning, W.3    Knippschild, U.4    Buchhop, S.5
  • 21
    • 0019364264 scopus 로고
    • Complex of simian virus 40 large-T antigen and host 53, 000-molecular-weight protein in monkey cells
    • Harlow, E., Pim, D.C. and Crawford, L.V. (1981) Complex of simian virus 40 large-T antigen and host 53, 000-molecular-weight protein in monkey cells. J. Virol. 37: 564-573.
    • (1981) J. Virol. , vol.37 , pp. 564-573
    • Harlow, E.1    Pim, D.C.2    Crawford, L.V.3
  • 22
    • 0020079972 scopus 로고
    • Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54kd cellular protein in transformed cells
    • Sarnow, P., Ho., Y.S., Willium, J. and Levine, A.J. (1982) Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54kd cellular protein in transformed cells. Cell 28: 387-394.
    • (1982) Cell , vol.28 , pp. 387-394
    • Sarnow, P.1    Ho, Y.S.2    Willium, J.3    Levine, A.J.4
  • 23
    • 0025271203 scopus 로고
    • Association of human papillomavirus type16 and 18 E6 protein with p53
    • Werness, B.A., Levine, A.J. and Howley, P.M. (1990) Association of human papillomavirus type16 and 18 E6 protein with p53. Science 248: 76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 24
    • 0001655748 scopus 로고
    • Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3
    • Wang, X.W., Forrester, K., Yeh, H., Feitelson, M.A., Gu, J.R. and Harris, C.C. (1994) Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc. Natl. Acad. Sci. USA 91: 2230-2234.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2230-2234
    • Wang, X.W.1    Forrester, K.2    Yeh, H.3    Feitelson, M.A.4    Gu, J.R.5    Harris, C.C.6
  • 25
    • 0030444279 scopus 로고    scopus 로고
    • p53: Upstream, downstream and off stream, review of the 8th p53 workshop
    • Dundee, July 5-9, 1996
    • Oren, M. and Prives, C. (1996) p53: upstream, downstream and off stream, review of the 8th p53 workshop (Dundee, July 5-9, 1996). Biochim. Biophys. Acta, 1288: R13-R19.
    • (1996) Biochim. Biophys. Acta , vol.1288
    • Oren, M.1    Prives, C.2
  • 26
    • 0029980043 scopus 로고    scopus 로고
    • p53 in growth control and neoplasia
    • Gottlieb, T.M. and Oren, M.(1996) p53 in growth control and neoplasia. Biochim. Biophys. Acta 1287: 77-102.
    • (1996) Biochim. Biophys. Acta , vol.1287 , pp. 77-102
    • Gottlieb, T.M.1    Oren, M.2
  • 27
    • 0029818965 scopus 로고    scopus 로고
    • Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin
    • Smith, M.L., Kontny, H.U., Zhan, Q., Sreenath, A., O'Connor, P.M. and Fornace, J.A. (1996) Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin. Oncogene 13: 2255-2263.
    • (1996) Oncogene , vol.13 , pp. 2255-2263
    • Smith, M.L.1    Kontny, H.U.2    Zhan, Q.3    Sreenath, A.4    O'Connor, P.M.5    Fornace, J.A.6
  • 28
    • 0028883179 scopus 로고
    • Tumor-suppressor p53 is a direct transcriptional activator of the human Bax gene
    • Miyashita, T. and Reed, J.C. (1995) Tumor-suppressor p53 is a direct transcriptional activator of the human Bax gene. Cell 80: 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 30
    • 0027944251 scopus 로고
    • Cyclin G is a transcriptional target of the p53 tumor suppressor protein
    • Okamoto, K. and Beach, D. (1994) Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO J. 13: 4816-4822.
    • (1994) EMBO J. , vol.13 , pp. 4816-4822
    • Okamoto, K.1    Beach, D.2
  • 31
    • 0029812028 scopus 로고    scopus 로고
    • p53 binds to a novel recognition sequence in the proximal promoter of the rat muscle creatine kinase gene and activates its transcription
    • Zhao, J., Schmieg, F.I., Logsdon, N., Freedman, D., Simmons, D.T. and Molloy, G.R. (1996) p53 binds to a novel recognition sequence in the proximal promoter of the rat muscle creatine kinase gene and activates its transcription. Oncogene 13: 293-302.
    • (1996) Oncogene , vol.13 , pp. 293-302
    • Zhao, J.1    Schmieg, F.I.2    Logsdon, N.3    Freedman, D.4    Simmons, D.T.5    Molloy, G.R.6
  • 32
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron, K.M., Volpert, O.V., Tainsky, M.A. and Bouck, N. (1994) Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265: 1582-1584.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 33
    • 0028865988 scopus 로고
    • Wild-type p53 and v-Src exert opposing influence on human vascular endothelial growth factor gene expression
    • Mukhopadhyay, D., Tsiokas, L. and Sukhatme, V.P. (1995) Wild-type p53 and v-Src exert opposing influence on human vascular endothelial growth factor gene expression. Cancer Res. 55: 6161-6165.
    • (1995) Cancer Res. , vol.55 , pp. 6161-6165
    • Mukhopadhyay, D.1    Tsiokas, L.2    Sukhatme, V.P.3
  • 37
    • 0025887476 scopus 로고
    • Wild type p53 can down-modulate the activity of various promoters
    • Ginsberg, D., Mechta, F., Yaniv, M. and Oren, M. (1991) Wild type p53 can down-modulate the activity of various promoters. Proc. Natl. Acad. Sci. USA 88: 9979-9983.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9979-9983
    • Ginsberg, D.1    Mechta, F.2    Yaniv, M.3    Oren, M.4
  • 39
    • 0029909531 scopus 로고    scopus 로고
    • Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein
    • Farmer, G., Friedlander, P., Colgan, J., Manley, J.L. and Prives, C. (1996) Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein. Nucl. Acids. Res. 24: 4281-4288.
    • (1996) Nucl. Acids. Res. , vol.24 , pp. 4281-4288
    • Farmer, G.1    Friedlander, P.2    Colgan, J.3    Manley, J.L.4    Prives, C.5
  • 40
    • 0025775929 scopus 로고
    • Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
    • Santhanam, U., Ray, A. and Sehgal, P.B. (1991) Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product. Proc. Natl. Acad. Sci. USA 88: 7605-7609.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7605-7609
    • Santhanam, U.1    Ray, A.2    Sehgal, P.B.3
  • 43
    • 0026555717 scopus 로고
    • Modulation of the activity of the promoter of the human MDR1 gene by Ras and p53
    • Chin, K.V., Ueda, K., Pastan, I. and Gottesman, M.M. (1992) Modulation of the activity of the promoter of the human MDR1 gene by Ras and p53. Science 255: 460-462.
    • (1992) Science , vol.255 , pp. 460-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 45
    • 0026065497 scopus 로고
    • Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression
    • Mercer, W.E., Shields, M.T., Lin, D., Appella, E. and Ullrich, S.J. (1991) Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression. Proc. Natl. Acad. Sci. USA 88: 1958-1962.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1958-1962
    • Mercer, W.E.1    Shields, M.T.2    Lin, D.3    Appella, E.4    Ullrich, S.J.5
  • 46
    • 0027469281 scopus 로고
    • Regulation of the human hsp70 promoter by p53
    • Agoff, S., Hou, J., Linzer, D. and Wu, B. (1993) Regulation of the human hsp70 promoter by p53. Science 259: 84-87.
    • (1993) Science , vol.259 , pp. 84-87
    • Agoff, S.1    Hou, J.2    Linzer, D.3    Wu, B.4
  • 47
    • 0029803281 scopus 로고    scopus 로고
    • Wild-type p53 negatively regulates the expression of a microtubule-associated protein
    • Murphy, M., Hinman, A. and Levine, A.J. (1996) Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes & Dev. 10: 2971-2980.
    • (1996) Genes & Dev. , vol.10 , pp. 2971-2980
    • Murphy, M.1    Hinman, A.2    Levine, A.J.3
  • 51
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for Rb protein
    • Chellappan, S.P., Hiebert, S.W., Mudryl, M., Horowitz, J.M. and Nevins, J.R. (1991) The E2F transcription factor is a cellular target for Rb protein. Cell 65: 1053-1061.
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.W.2    Mudryl, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 52
    • 0026537277 scopus 로고
    • The interaction of Rb with E2F coincides with the transcriptional activity of E2F
    • Hiebert, S.W., Chellappan, S.P., Horowitz, J.M. and Nevins, J.R. (1992) The interaction of Rb with E2F coincides with the transcriptional activity of E2F. Genes & Dev. 4: 177-185.
    • (1992) Genes & Dev. , vol.4 , pp. 177-185
    • Hiebert, S.W.1    Chellappan, S.P.2    Horowitz, J.M.3    Nevins, J.R.4
  • 53
    • 0030561571 scopus 로고    scopus 로고
    • The retinoblastoma protein pathway and the restriction point
    • Bartek, J., Bartkova, J. and Lukas, J. (1996) The retinoblastoma protein pathway and the restriction point, Curr. Opin. Cell. Biol. 8: 805-814.
    • (1996) Curr. Opin. Cell. Biol. , vol.8 , pp. 805-814
    • Bartek, J.1    Bartkova, J.2    Lukas, J.3
  • 54
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
    • Waga, S., Hannon, G.J., Beach, D. and Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369: 574-577.
    • (1994) Nature , vol.369 , pp. 574-577
    • Waga, S.1    Hannon, G.J.2    Beach, D.3    Stillman, B.4
  • 55
    • 0023091938 scopus 로고
    • Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein
    • Prelich, G., Tan, C.K., Kostura, M., Mathews, M.B., So, A.G., Downney, K.M. and Stillman, B. (1987) Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. Nature 326: 517-520.
    • (1987) Nature , vol.326 , pp. 517-520
    • Prelich, G.1    Tan, C.K.2    Kostura, M.3    Mathews, M.B.4    So, A.G.5    Downney, K.M.6    Stillman, B.7
  • 56
    • 0026098470 scopus 로고
    • Properties of DNA polymerase δ and ε, and their roles in eukaryotic DNA replication
    • Bambara, R.A. and Jessee, C.B. (1991) Properties of DNA polymerase δ and ε, and their roles in eukaryotic DNA replication. Biochim Biophys Acta 1088: 11-14.
    • (1991) Biochim Biophys Acta , vol.1088 , pp. 11-14
    • Bambara, R.A.1    Jessee, C.B.2
  • 57
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane, D. (1992) p53, guardian of the genome. Nature 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.1
  • 59
    • 0029013273 scopus 로고
    • p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
    • Lee, S., Elenbaas, B., Levine, A. and Griffith, J. (1995) p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. Cell 81: 1013-1020.
    • (1995) Cell , vol.81 , pp. 1013-1020
    • Lee, S.1    Elenbaas, B.2    Levine, A.3    Griffith, J.4
  • 65
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A. and Oren, M. (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352: 345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 66
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A. and Jacks, T. (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 68
    • 0027283604 scopus 로고
    • Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents
    • Lotem, J. and Sachs, L. (1993) Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood 83: 1092-1096.
    • (1993) Blood , vol.83 , pp. 1092-1096
    • Lotem, J.1    Sachs, L.2
  • 69
    • 0030013337 scopus 로고    scopus 로고
    • Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
    • Attardi, L.D., Lowe, S.W., Brugarolas, J. and Jacks, T. (1996) Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J. 15: 3693-3701.
    • (1996) EMBO J. , vol.15 , pp. 3693-3701
    • Attardi, L.D.1    Lowe, S.W.2    Brugarolas, J.3    Jacks, T.4
  • 70
    • 0029143395 scopus 로고
    • Essential role for p53-mediated transcription in E1A-induced apoptosis
    • Sabbatini, P., Lin, J., Levine, A.J. and White, E. (1995) Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes & Dev. 9: 2184-2192.
    • (1995) Genes & Dev. , vol.9 , pp. 2184-2192
    • Sabbatini, P.1    Lin, J.2    Levine, A.J.3    White, E.4
  • 71
    • 0031025688 scopus 로고    scopus 로고
    • Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis
    • Desaintes, C., Demeret, C., Goyat, S., Yaniv, M. and Thierry, F. (1997) Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis. EMBO J. 16: 504-514.
    • (1997) EMBO J. , vol.16 , pp. 504-514
    • Desaintes, C.1    Demeret, C.2    Goyat, S.3    Yaniv, M.4    Thierry, F.5
  • 72
    • 0028070989 scopus 로고
    • p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles, C., Helmberg, A. and Karin, M. (1994) p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370: 220-223.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 73
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by trans-activation deficient p53
    • Haupt, Y., Rowan, S., Shaulian, E., Vousden, K.H. and Oren, M. (1995) Induction of apoptosis in HeLa cells by trans-activation deficient p53. Genes & Dev. 9: 2170-2183.
    • (1995) Genes & Dev. , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 75
  • 76
    • 0028238213 scopus 로고
    • Immediate early up-regulation of Bax expression by p53 but not TGFβ1: A paradigm for distinct apoptotic pathways
    • Selvakumaran, M., Lin, H., Miyashita, T., Wang, H., Krajewski, S., Reed, J., Hoffman, B. and Liebermann, D. (1994) Immediate early up-regulation of Bax expression by p53 but not TGFβ1: A paradigm for distinct apoptotic pathways. Oncogene 9: 1791-1798.
    • (1994) Oncogene , vol.9 , pp. 1791-1798
    • Selvakumaran, M.1    Lin, H.2    Miyashita, T.3    Wang, H.4    Krajewski, S.5    Reed, J.6    Hoffman, B.7    Liebermann, D.8
  • 77
    • 0027944228 scopus 로고
    • Induction of Bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
    • Zhan, Q., Fan, S., Bae, I., Guillouf, C., Liebermann, D.A., O'Connor, P.M. and Fornace, A.J. Jr. (1994) Induction of Bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene 9: 3743-3751.
    • (1994) Oncogene , vol.9 , pp. 3743-3751
    • Zhan, Q.1    Fan, S.2    Bae, I.3    Guillouf, C.4    Liebermann, D.A.5    O'Connor, P.M.6    Fornace A.J., Jr.7
  • 78
    • 0026722655 scopus 로고
    • Cooperative interaction between c-myc and bcl-2 proto-oncogenes
    • Fanidi, A.E., Harrington, A. and Evan, G. (1992) Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 359: 554-556.
    • (1992) Nature , vol.359 , pp. 554-556
    • Fanidi, A.E.1    Harrington, A.2    Evan, G.3
  • 79
    • 0028222955 scopus 로고
    • Bcl-2 blocks p53-dependent apoptosis
    • Chiou, S.K., Rao, L. and White, E. (1994) Bcl-2 blocks p53-dependent apoptosis. Mol. Cell. Biol. 14: 2556-2563.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2556-2563
    • Chiou, S.K.1    Rao, L.2    White, E.3
  • 80
    • 0025255538 scopus 로고
    • Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez, G., London, L., Hockenbery, D., Alexander, M., Mckearn, J.P. and Korsmeyer, S.J. (1990) Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 144: 3602-3610.
    • (1990) J. Immunol. , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    Mckearn, J.P.5    Korsmeyer, S.J.6
  • 82
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • Oltvai, Z.N., Milliman, C.L. and Korsmeyer, S.J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 85
    • 0023612470 scopus 로고
    • Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes
    • Sellins, K.S. and Cohen, J.J. (1987) Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol. 139: 3199-3206.
    • (1987) J. Immunol. , vol.139 , pp. 3199-3206
    • Sellins, K.S.1    Cohen, J.J.2
  • 86
    • 0028224017 scopus 로고
    • Radiation response of mouse lymphoid and myeloid cell lines. Part I. Sensitivity to killing by ionizing radiation, rate of loss of viability, and cell type of origin
    • Radford, I.R. (1994) Radiation response of mouse lymphoid and myeloid cell lines. Part I. Sensitivity to killing by ionizing radiation, rate of loss of viability, and cell type of origin. Int. J. Radiat. Biol. 65: 203-215.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 203-215
    • Radford, I.R.1
  • 87
    • 0027948119 scopus 로고
    • p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines
    • Radford, I.R. (1994) p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines. Int. J. Radiat. Biol. 66: 557-560.
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 557-560
    • Radford, I.R.1
  • 88
    • 0023847959 scopus 로고
    • Radiation-induced interphase death of rat thymocytec is internally programmed (apoptosis)
    • Yamada, T. and Ohyama, H. (1988) Radiation-induced interphase death of rat thymocytec is internally programmed (apoptosis). Int. J. Radiat. Biol. 53: 65-75.
    • (1988) Int. J. Radiat. Biol. , vol.53 , pp. 65-75
    • Yamada, T.1    Ohyama, H.2
  • 89
    • 0017739418 scopus 로고
    • Extreme sensitivity of some intestinal crypt cells to X and γ-irradiation
    • Potten, C.S. (1977) Extreme sensitivity of some intestinal crypt cells to X and γ-irradiation. Nature 269: 518-520.
    • (1977) Nature , vol.269 , pp. 518-520
    • Potten, C.S.1
  • 90
    • 0028301094 scopus 로고
    • p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation
    • Clarke, A.R., Gledhill, S., Hooper, M.L., Bird, C.C. and Wyllie, A.H. (1994) p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation. Oncogene 9: 1767-1773.
    • (1994) Oncogene , vol.9 , pp. 1767-1773
    • Clarke, A.R.1    Gledhill, S.2    Hooper, M.L.3    Bird, C.C.4    Wyllie, A.H.5
  • 91
    • 0023812739 scopus 로고
    • Cell death by apoptosis following X-irradiation of the foetal and neonatal rat kidney
    • Gobe, G.C., Axelsen, R.A., Harmon, B.V. and Allan, D.J. (1988) Cell death by apoptosis following X-irradiation of the foetal and neonatal rat kidney. Int. J. Radiat. Biol. 54: 567-576.
    • (1988) Int. J. Radiat. Biol. , vol.54 , pp. 567-576
    • Gobe, G.C.1    Axelsen, R.A.2    Harmon, B.V.3    Allan, D.J.4
  • 93
    • 0026653689 scopus 로고
    • Radiosensitization by fluorodeoxyuridine: Effects of thymidylate synthase inhibition and cell synchronization
    • Miller, E.M. and Kinsella, T.J. (1992) Radiosensitization by fluorodeoxyuridine: effects of thymidylate synthase inhibition and cell synchronization. Cancer Res. 52: 1687-1694.
    • (1992) Cancer Res. , vol.52 , pp. 1687-1694
    • Miller, E.M.1    Kinsella, T.J.2
  • 94
    • 0028019863 scopus 로고
    • The role of cell cycle redistribution in radiosensitization: Implications regarding the mechanism of fluorodeoyuridine radiosensitization
    • McGinn, C.J., Miller, E.M., Lindstrom, M.J., Kunugi, K.A., Johnston, P.G. and Kinsella, T.J. (1994) The role of cell cycle redistribution in radiosensitization: implications regarding the mechanism of fluorodeoyuridine radiosensitization. Int. J. Radiat. Oncol. Biol. Phys. 30: 851-859.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.30 , pp. 851-859
    • McGinn, C.J.1    Miller, E.M.2    Lindstrom, M.J.3    Kunugi, K.A.4    Johnston, P.G.5    Kinsella, T.J.6
  • 96
    • 0029811984 scopus 로고    scopus 로고
    • Genetic determinants of p53-induced apoptosis and growth arrest
    • Polyak, K., Waldman, T., He, T.C., Kinzler, K.W. and Vogelstein, B. (1996) Genetic determinants of p53-induced apoptosis and growth arrest. Genes & Dev. 10: 1945-1952.
    • (1996) Genes & Dev. , vol.10 , pp. 1945-1952
    • Polyak, K.1    Waldman, T.2    He, T.C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 97
    • 0029004353 scopus 로고
    • Raf-1 phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo
    • Jamal, S. and Ziff, E.B. (1995) Raf-1 phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo. Oncogene 10: 2095-2101.
    • (1995) Oncogene , vol.10 , pp. 2095-2101
    • Jamal, S.1    Ziff, E.B.2
  • 99
    • 0030066023 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage
    • Price, B.D. and Youmell, M.B., (1996) The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage. Cancer Res. 56: 246-250.
    • (1996) Cancer Res. , vol.56 , pp. 246-250
    • Price, B.D.1    Youmell, M.B.2
  • 100
    • 0028880649 scopus 로고
    • Ataxia-telangiectasia and cellular responses to DNA damage
    • Meyn, M.S. (1995) Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Res. 55: 5591-6001.
    • (1995) Cancer Res. , vol.55 , pp. 5591-6001
    • Meyn, M.S.1
  • 101
    • 0019166395 scopus 로고
    • The effect of ionizing radiation on DNA synthesis in ataxia-telangiectasia cells
    • Houldsworth, J. and Levin, M.F. (1980) The effect of ionizing radiation on DNA synthesis in ataxia-telangiectasia cells. Nucl. Acids Res. 8: 3709-3720.
    • (1980) Nucl. Acids Res. , vol.8 , pp. 3709-3720
    • Houldsworth, J.1    Levin, M.F.2
  • 102
    • 0028213350 scopus 로고
    • Radiosensitivity in ataxia-telangiectasia: Anomalies in radiation-induced cell cycle delay
    • Beamish, H. and Lavin, M.F. (1994) Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay. Int. J. Radiat. Biol. 65: 175-184.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 175-184
    • Beamish, H.1    Lavin, M.F.2
  • 103
    • 0029821651 scopus 로고    scopus 로고
    • Dual role of ATM in the cellular response to radiation and in cell growth control
    • Xu, Y. and Baltimore, D. (1996) Dual role of ATM in the cellular response to radiation and in cell growth control. Genes & Dev. 10: 2401-2410.
    • (1996) Genes & Dev. , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2
  • 105
    • 0028167599 scopus 로고
    • NF-κB activation of p53
    • Wu, H. and Lozano, G. (1994) NF-κB activation of p53. J. Biol. Chem. 269: 20067-20074.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20067-20074
    • Wu, H.1    Lozano, G.2
  • 106
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins, N.D., Felzien, L.K., Betts, J.C., Leung, K., Beach, D.H. and Nabel, G.J. (1997) Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 275: 523-525.
    • (1997) Science , vol.275 , pp. 523-525
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 107
    • 0029061587 scopus 로고
    • Correction of radiation sensitivity in ataxia-telangiectasia cells by a truncated IκB-α
    • Jung, M., Zhang, Y., Lee, S. and Dritschilo, A. (1995) Correction of radiation sensitivity in ataxia-telangiectasia cells by a truncated IκB-α. Science 268: 1619-1621.
    • (1995) Science , vol.268 , pp. 1619-1621
    • Jung, M.1    Zhang, Y.2    Lee, S.3    Dritschilo, A.4
  • 108
    • 0029073142 scopus 로고
    • Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
    • Datto, M.B., Li, Y., Panus, J.F., Howe, D.J., Xiong, Y. and Wang, X.F. (1995) Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. Sci. USA 92: 5545-5549.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5545-5549
    • Datto, M.B.1    Li, Y.2    Panus, J.F.3    Howe, D.J.4    Xiong, Y.5    Wang, X.F.6
  • 109
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Rosette, C. and Karin, M. (1996) Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274: 1194-1197.
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 111
    • 0028807042 scopus 로고
    • Activation and nuclear translocation of mitogen-activated kinase by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase
    • Urich, M., El Shemerly, M.Y.M., Besser, D., Nagamine, Y. and Ballmer-Hofer, K. (1995) Activation and nuclear translocation of mitogen-activated kinase by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase. J. Biol. Chem. 270: 29286-29292.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29286-29292
    • Urich, M.1    El Shemerly, M.Y.M.2    Besser, D.3    Nagamine, Y.4    Ballmer-Hofer, K.5
  • 112
    • 0030596121 scopus 로고    scopus 로고
    • Suppression of heat-induced hsp accumulation by cisplatin in human glioblastoma cells
    • Matsumoto, H., Hayashi, S., Shioura, H., Ohtsubo, T., Ohnishi, T. and Kano, E. (1996) Suppression of heat-induced hsp accumulation by cisplatin in human glioblastoma cells. Cancer Lett. 110: 253-257.
    • (1996) Cancer Lett. , vol.110 , pp. 253-257
    • Matsumoto, H.1    Hayashi, S.2    Shioura, H.3    Ohtsubo, T.4    Ohnishi, T.5    Kano, E.6
  • 113
    • 0031586592 scopus 로고    scopus 로고
    • Bifunctional effects of a protein kinase inhibitor (H-7) on heat-induced p53-dependent WAF1 accumulation
    • in press
    • Wang, X., Takahashi, A., Ohnishi, K., Matsumoto, H., Suda, K. and Ohnishi, T. (1997) Bifunctional effects of a protein kinase inhibitor (H-7) on heat-induced p53-dependent WAF1 accumulation. Exp. Cell Res. in press.
    • (1997) Exp. Cell Res.
    • Wang, X.1    Takahashi, A.2    Ohnishi, K.3    Matsumoto, H.4    Suda, K.5    Ohnishi, T.6
  • 114
    • 0027090115 scopus 로고
    • Mammalian genes induced by radiation; activation of genes associated with growth control
    • Fornace, A.J. Jr. (1992) Mammalian genes induced by radiation; activation of genes associated with growth control. Annu. Rev. Genet. 26: 507-526.
    • (1992) Annu. Rev. Genet. , vol.26 , pp. 507-526
    • Fornace A.J., Jr.1
  • 115
    • 0027820888 scopus 로고
    • DNA damage, gene expression, growth arrest and cell death
    • Gewirtz, D.A. (1993) DNA damage, gene expression, growth arrest and cell death. Oncol. Res. 5: 397-408.
    • (1993) Oncol. Res. , vol.5 , pp. 397-408
    • Gewirtz, D.A.1
  • 117
    • 0028263811 scopus 로고
    • c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington, E.A., Bennett, M.R., Fanidi, A. and Evan, G.I. (1994) c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13: 3286-3295.
    • (1994) EMBO J. , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 119
    • 0028302712 scopus 로고
    • Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis
    • Haimovitz-Friedman, A., Balaban, N., MclLoughlin, M., Ehleiter, D., Michaeli, J., Vlodavsky, I. and Fuks, Z. (1994) Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis. Cancer Res. 54: 2591-2597.
    • (1994) Cancer Res. , vol.54 , pp. 2591-2597
    • Haimovitz-Friedman, A.1    Balaban, N.2    Mclloughlin, M.3    Ehleiter, D.4    Michaeli, J.5    Vlodavsky, I.6    Fuks, Z.7
  • 121
    • 0028171968 scopus 로고
    • Mediation of c-myc-induced apoptosis by p53
    • Hermeking, H. and Eick, D. (1994) Mediation of c-myc-induced apoptosis by p53. Science 265: 2091-2093.
    • (1994) Science , vol.265 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 123
    • 0027246692 scopus 로고
    • Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells
    • Lotem, J. and Sachs, L. (1993) Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells. Cell Growth & Diff. 4: 41-47.
    • (1993) Cell Growth & Diff. , vol.4 , pp. 41-47
    • Lotem, J.1    Sachs, L.2
  • 124
    • 0029996277 scopus 로고    scopus 로고
    • Apoptotic response to oncogenic stimuli: Cooperative and antagonistic interactions between c-Myb and the growth suppressor p53
    • Sala, A., Casella, I., Grasso, L., Bellon, T., Reed, J.C., Miyashita, T. and Peschle, C. (1996) Apoptotic response to oncogenic stimuli: cooperative and antagonistic interactions between c-Myb and the growth suppressor p53. Cancer Res. 56: 1991-1996.
    • (1996) Cancer Res. , vol.56 , pp. 1991-1996
    • Sala, A.1    Casella, I.2    Grasso, L.3    Bellon, T.4    Reed, J.C.5    Miyashita, T.6    Peschle, C.7
  • 125
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
    • Nevins, J.R. (1992) E2F: A link between the Rb tumor suppressor protein and viral oncoproteins. Science 258: 424-428.
    • (1992) Science , vol.258 , pp. 424-428
    • Nevins, J.R.1
  • 126
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin, X.Q., Livingston, D.M., Kaelin, W.G.J. and Adams, P.D. (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA 91: 10918-10922.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin, W.G.J.3    Adams, P.D.4
  • 127
    • 0028222124 scopus 로고
    • p53 and E2F-1 cooperate to mediate apoptosis
    • Wu, X. and Levine, A.J. (1994) p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA 91: 3602-3606.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 130
    • 0029050533 scopus 로고
    • Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis
    • Almasan, A., Yin, Y., Kelly, R.E., Lee, E.Y., Bradley, A., Li, W., Bertino, J.R. and Wahl, G.M. (1995) Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92: 5436-5440.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5436-5440
    • Almasan, A.1    Yin, Y.2    Kelly, R.E.3    Lee, E.Y.4    Bradley, A.5    Li, W.6    Bertino, J.R.7    Wahl, G.M.8
  • 131
    • 0029264714 scopus 로고
    • Apoptosis by antitumor agents and other factors in relation to cell cycle checkpoints
    • Kondo, S. (1995) Apoptosis by antitumor agents and other factors in relation to cell cycle checkpoints. J. Radiat. Res. 36: 56-62.
    • (1995) J. Radiat. Res. , vol.36 , pp. 56-62
    • Kondo, S.1
  • 133
    • 0029874308 scopus 로고    scopus 로고
    • p53-dependent apoptosis suppresses radiation-induced teratogenesis
    • Norimura, T., Nomoto, S., Katsuki, M., Gondo, Y. and Kondo, S. (1996) p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nature Med. 2: 577-580.
    • (1996) Nature Med. , vol.2 , pp. 577-580
    • Norimura, T.1    Nomoto, S.2    Katsuki, M.3    Gondo, Y.4    Kondo, S.5
  • 134
    • 0029858143 scopus 로고    scopus 로고
    • V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors
    • Guidos, C.J., Williams, C.J., Grandal, I., Knowles, G., Huang, M.T. and Danska, J.S. (1996) V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. Genes & Dev. 10: 2038-2054.
    • (1996) Genes & Dev. , vol.10 , pp. 2038-2054
    • Guidos, C.J.1    Williams, C.J.2    Grandal, I.3    Knowles, G.4    Huang, M.T.5    Danska, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.