-
1
-
-
0027179491
-
Present status and future prospects for HIV therapies
-
Johnston, M. I., and D. F. Hoth. Present status and future prospects for HIV therapies. Science (Washington D. C.) 260:1286-1293 (1993).
-
(1993)
Science (Washington D. C.)
, vol.260
, pp. 1286-1293
-
-
Johnston, M.I.1
Hoth, D.F.2
-
2
-
-
0029871472
-
Effects of nucleotide analogs on human immunodeficiency virus integrase
-
Mazumder, A., N. Neamati, J.-P. Sommadossi, G. Gosselin, R. F. Schinazi, J.-L. Imbach, and Y. Pommier. Effects of nucleotide analogs on human immunodeficiency virus integrase. Mol. Pharmacol. 49:621-628 (1996).
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 621-628
-
-
Mazumder, A.1
Neamati, N.2
Sommadossi, J.-P.3
Gosselin, G.4
Schinazi, R.F.5
Imbach, J.-L.6
Pommier, Y.7
-
3
-
-
2642685126
-
Inhibitors of HIV replication that inhibit HIV integrase
-
Robinson, W. E., Jr., M. G. Reinecke, S. Abdel-Malek, Q. Jia, and S. A. Chow. Inhibitors of HIV replication that inhibit HIV integrase. Proc. Natl. Acad. Sci. USA 93:6326-6331 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6326-6331
-
-
Robinson Jr., W.E.1
Reinecke, M.G.2
Abdel-Malek, S.3
Jia, Q.4
Chow, S.A.5
-
4
-
-
0029990185
-
Alternate strand DNA triple helix-mediated inhibition of HIV-1 U5 long terminal repeat integration in vitro
-
Bouziane, M., D. I. Cherny, J. F. Mouscadet, and C. Auclair. Alternate strand DNA triple helix-mediated inhibition of HIV-1 U5 long terminal repeat integration in vitro. J. Biol. Chem. 271:10359-10364 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10359-10364
-
-
Bouziane, M.1
Cherny, D.I.2
Mouscadet, J.F.3
Auclair, C.4
-
5
-
-
0002915381
-
Retroviruses
-
(D. Berg, and M. Howe, eds.). American Society of Microbiology, Washington, DC
-
Varmus, H. E., and P. O. Brown. Retroviruses, in Mobile DNA (D. Berg, and M. Howe, eds.). American Society of Microbiology, Washington, DC, 53-108 (1989).
-
(1989)
Mobile DNA
, pp. 53-108
-
-
Varmus, H.E.1
Brown, P.O.2
-
8
-
-
0028242724
-
Inhibition of human immunodeficiency virus type 1 integrase by 3′-azido-3′-deoxythymidylate
-
Mazumder, A., D. Cooney, R. Agbaria, M. Gupta, and Y. Pommier. Inhibition of human immunodeficiency virus type 1 integrase by 3′-azido-3′-deoxythymidylate. Proc. Natl. Acad. Sci. USA 91:5771-5775 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5771-5775
-
-
Mazumder, A.1
Cooney, D.2
Agbaria, R.3
Gupta, M.4
Pommier, Y.5
-
9
-
-
0029065930
-
Cosalane analogs with enhanced potencies as inhibitors of HIV-1 protease and integrase
-
Cushman, M., W. M. Golebiewski, Y. Pommier, A. Mazumder, D. Reymen, E. De Clerq, L. Graham, and W. G. Rice. Cosalane analogs with enhanced potencies as inhibitors of HIV-1 protease and integrase. J. Med. Chem. 38:443-452 (1995).
-
(1995)
J. Med. Chem.
, vol.38
, pp. 443-452
-
-
Cushman, M.1
Golebiewski, W.M.2
Pommier, Y.3
Mazumder, A.4
Reymen, D.5
De Clerq, E.6
Graham, L.7
Rice, W.G.8
-
10
-
-
0028798026
-
Inhibition of human immunodeficiency virus integrase by bis-catechols
-
LaFemina, R. L., P. L. Graham, K. LeGrow, J. C. Hastings, A. Wolfe, S. D. Young, E. A. Emini, and D. J. Hazuda. Inhibition of human immunodeficiency virus integrase by bis-catechols. Antimicrob. Agents Chemother. 39:320-324 (1995).
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 320-324
-
-
LaFemina, R.L.1
Graham, P.L.2
LeGrow, K.3
Hastings, J.C.4
Wolfe, A.5
Young, S.D.6
Emini, E.A.7
Hazuda, D.J.8
-
11
-
-
0028820595
-
Effects of tyrphostins, protein kinase inhibitors, on human immunodeficiency virus type 1 integrase
-
Mazumder, A., A. Gazit, A. Levitzki, M. Nicklaus, J. Yung, G. Kohlhagen, and Y. Pommier. Effects of tyrphostins, protein kinase inhibitors, on human immunodeficiency virus type 1 integrase. Biochemistry 34:15111-15122 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 15111-15122
-
-
Mazumder, A.1
Gazit, A.2
Levitzki, A.3
Nicklaus, M.4
Yung, J.5
Kohlhagen, G.6
Pommier, Y.7
-
12
-
-
0028928463
-
Inhibition of human immunodeficiency virus type 1 integrase by curcumin
-
Mazumder, A., K. Raghavan, J. N. Weinstein, K. W. Kohn, and Y. Pommier. Inhibition of human immunodeficiency virus type 1 integrase by curcumin. Biochem. Pharmacol. 49:1165-1170 (1995).
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 1165-1170
-
-
Mazumder, A.1
Raghavan, K.2
Weinstein, J.N.3
Kohn, K.W.4
Pommier, Y.5
-
13
-
-
0030061628
-
Inhibition of RNase H activity by nucleotide dimers and monomers
-
Allen, S. J. W., S. H. Krawczyk, L. R. McGee, N. Bischofberger, A. S. Mulato, and J. M. Cherrington. Inhibition of RNase H activity by nucleotide dimers and monomers. Antiviral Chem. Chemother. 7:37-45 (1996).
-
(1996)
Antiviral Chem. Chemother.
, vol.7
, pp. 37-45
-
-
Allen, S.J.W.1
Krawczyk, S.H.2
McGee, L.R.3
Bischofberger, N.4
Mulato, A.S.5
Cherrington, J.M.6
-
14
-
-
0026330796
-
HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
-
Engelman, A., K. Mizuuchi, and R. Craigie. HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer. Cell 67:1211-1221 (1991).
-
(1991)
Cell
, vol.67
, pp. 1211-1221
-
-
Engelman, A.1
Mizuuchi, K.2
Craigie, R.3
-
15
-
-
0026348879
-
Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein
-
Vink, C., E. Yeheskiely, G. A. van der Marel, J. H. van Boom, and R. H. Plasterk. Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein. Nucleic Acids Res. 19:6691-6698 (1991).
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 6691-6698
-
-
Vink, C.1
Yeheskiely, E.2
Van Der Marel, G.A.3
Van Boom, J.H.4
Plasterk, R.H.5
-
16
-
-
0026549933
-
Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus
-
Chow, S. A., K. A. Vincent, V. Ellison, and P. O. Brown. Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus. Science (Washington D. C.) 255:723-726 (1992).
-
(1992)
Science (Washington D. C.)
, vol.255
, pp. 723-726
-
-
Chow, S.A.1
Vincent, K.A.2
Ellison, V.3
Brown, P.O.4
-
17
-
-
0027456715
-
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
-
Bushman, F. D., A. Engelman, I. Palmer, P. Wingfield, and R. Craigie. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc. Natl. Acad. Sci. USA 90:3428-3432 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3428-3432
-
-
Bushman, F.D.1
Engelman, A.2
Palmer, I.3
Wingfield, P.4
Craigie, R.5
-
18
-
-
0028070994
-
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds
-
Fesen, M., Y. Pommier, F. Leteurtre, S. Hiroguchi, J. Yung, and K. W. Kohn. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem. Pharmacol. 48:595-608 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 595-608
-
-
Fesen, M.1
Pommier, Y.2
Leteurtre, F.3
Hiroguchi, S.4
Yung, J.5
Kohn, K.W.6
-
19
-
-
0028087997
-
Detection and characterization of a functional complex of human immunodeficiency virus type 1 integrase and its DNA substrate by UV cross-linking
-
Yoshinaga, T., Y. Kimura-Ohtani, and T. Fujiwara. Detection and characterization of a functional complex of human immunodeficiency virus type 1 integrase and its DNA substrate by UV cross-linking. J. Virol. 68:5690-5697 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 5690-5697
-
-
Yoshinaga, T.1
Kimura-Ohtani, Y.2
Fujiwara, T.3
-
20
-
-
0001587762
-
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2′,3′-dideoxynucleosides
-
Mitsuya, H., and S. Broder. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2′,3′-dideoxynucleosides. Proc. Natl. Acad. Sci. USA 83:1911-1915 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 1911-1915
-
-
Mitsuya, H.1
Broder, S.2
-
21
-
-
0026072804
-
Substrate specificity of recombinant human immunodeficiency virus integrase protein
-
LaFemina, R. L., P. L. Callahan, and M. G. Cordingley. Substrate specificity of recombinant human immunodeficiency virus integrase protein. J. Virol. 65:5624-5630 (1991).
-
(1991)
J. Virol.
, vol.65
, pp. 5624-5630
-
-
LaFemina, R.L.1
Callahan, P.L.2
Cordingley, M.G.3
-
22
-
-
0026095906
-
Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage
-
Vink, C., G. D. van, Y. Elgersma, and R. H. Plasterk. Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage. J. Virol. 65:4636-4644 (1991).
-
(1991)
J. Virol.
, vol.65
, pp. 4636-4644
-
-
Vink, C.1
Van, G.D.2
Elgersma, Y.3
Plasterk, R.H.4
-
23
-
-
0029132791
-
DNA analogues with nonphosphodiester backbones
-
Nielsen, P. E. DNA analogues with nonphosphodiester backbones. Annu. Rev. Biophys. Biomol. Struct. 24:167-183 (1995).
-
(1995)
Annu. Rev. Biophys. Biomol. Struct.
, vol.24
, pp. 167-183
-
-
Nielsen, P.E.1
-
24
-
-
0027362485
-
HIV-1 reverse transcriptase: Inhibition by 2′,5′-oligoadenylates
-
Sobol, R. W., W. L. Fisher, N. L. Reichenbach, A. Kumar, W. A. Beard, S. H. Wilson, R. Charubala, W. Pfleiderer, and R. J. Suhadolnik. HIV-1 reverse transcriptase: inhibition by 2′,5′-oligoadenylates. Biochemistry 32:12112-12118 (1993).
-
(1993)
Biochemistry
, vol.32
, pp. 12112-12118
-
-
Sobol, R.W.1
Fisher, W.L.2
Reichenbach, N.L.3
Kumar, A.4
Beard, W.A.5
Wilson, S.H.6
Charubala, R.7
Pfleiderer, W.8
Suhadolnik, R.J.9
-
25
-
-
0026649557
-
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
-
Engelman, A., and R. Craigie. Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J. Virol. 66:6361-6369 (1992).
-
(1992)
J. Virol.
, vol.66
, pp. 6361-6369
-
-
Engelman, A.1
Craigie, R.2
-
26
-
-
0028067324
-
The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding
-
Engelman, A., A. B. Hickman, and R. Craigie. The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. J. Virol. 68:5911-5917 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 5911-5917
-
-
Engelman, A.1
Hickman, A.B.2
Craigie, R.3
-
27
-
-
0029166510
-
Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase
-
Mazumder, A., and Y. Pommier. Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase. Nucleic Acids Res. 23:2865-2871 (1995).
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 2865-2871
-
-
Mazumder, A.1
Pommier, Y.2
-
28
-
-
0028089732
-
DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein
-
van Den Ent, F. M. I., C. Vink, and R. H. A. Plasterk. DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein. J. Virol. 68:7825-7832 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 7825-7832
-
-
Van Den Ent, F.M.I.1
Vink, C.2
Plasterk, R.H.A.3
-
29
-
-
0028239062
-
A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro
-
Ellison, V., and P. O. Brown. A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proc Natl. Acad. Sci. USA 91:7316-7320 (1994).
-
(1994)
Proc Natl. Acad. Sci. USA
, vol.91
, pp. 7316-7320
-
-
Ellison, V.1
Brown, P.O.2
-
30
-
-
0027222149
-
Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction
-
Carteau, S., J. F. Mouscadet, H. Goulaouic, F. Subra, and C. Auclair. Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction. Arch. Biochem. Biophys. 305:606-610 (1993).
-
(1993)
Arch. Biochem. Biophys.
, vol.305
, pp. 606-610
-
-
Carteau, S.1
Mouscadet, J.F.2
Goulaouic, H.3
Subra, F.4
Auclair, C.5
-
31
-
-
0026568640
-
Integration of human immunodeficiency virus DNA: Adduct interference analysis of required DNA sites
-
Bushman, F. D., and R. Craigie. Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites. Proc. Natl. Acad. Sci. USA 89:3458-3462 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3458-3462
-
-
Bushman, F.D.1
Craigie, R.2
-
32
-
-
0028020102
-
Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both extent of 3′-processing and choice of nucleophile by HIV-1 integrase
-
Mazumder, A., M. Gupta, and Y. Pommier. Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both extent of 3′-processing and choice of nucleophile by HIV-1 integrase. Nucleic Acids Res. 22:4441-4448 (1994).
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4441-4448
-
-
Mazumder, A.1
Gupta, M.2
Pommier, Y.3
-
34
-
-
0029062402
-
Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: The phenanthroline-cuprous complex
-
Mazumder, A., M. Gupta, D. M. Perrin, D. S. Sigman, M. Rabinovitz, and Y. Pommier. Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: the phenanthroline-cuprous complex. AIDS Res. Hum. Retroviruses 11:115-125 (1995).
-
(1995)
AIDS Res. Hum. Retroviruses
, vol.11
, pp. 115-125
-
-
Mazumder, A.1
Gupta, M.2
Perrin, D.M.3
Sigman, D.S.4
Rabinovitz, M.5
Pommier, Y.6
-
35
-
-
0027438203
-
Inhibition of visna virus replication by 2′,3′-dideoxynucleosides and acyclic nucleoside phosphonate analogs
-
Thormar, H., J. Balzarini, A. Holy, J. Jindrich, I. Rosenberg, Z. Debyser, J. Desmyter, and E. DeClercq. Inhibition of visna virus replication by 2′,3′-dideoxynucleosides and acyclic nucleoside phosphonate analogs. Antimicrob. Agents Chemother. 37:2540-25444 (1993).
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 2540-25444
-
-
Thormar, H.1
Balzarini, J.2
Holy, A.3
Jindrich, J.4
Rosenberg, I.5
Debyser, Z.6
Desmyter, J.7
DeClercq, E.8
-
36
-
-
0029965208
-
Intramolecular G-quartet motifs confer nuclease resistance to a potent anti-HIV oligonucleotide
-
Bishop, J. S., J. K. Guy-Caffey, J. O. Ojwang, S. R. Smith, M. E. Hogan, P. A. Cossum, R. F. Rando, and N. Chaudhary. Intramolecular G-quartet motifs confer nuclease resistance to a potent anti-HIV oligonucleotide. J. Biol. Chem. 271:5698-5703 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5698-5703
-
-
Bishop, J.S.1
Guy-Caffey, J.K.2
Ojwang, J.O.3
Smith, S.R.4
Hogan, M.E.5
Cossum, P.A.6
Rando, R.F.7
Chaudhary, N.8
-
37
-
-
0029964978
-
Inhibition of human immunodeficiency virus type 1 integrase by guanosine quartet structures
-
Mazumder, A., N. Neamati, J. O. Ojwang, S. Sunder, R. F. Rando, and Y. Pommier. Inhibition of human immunodeficiency virus type 1 integrase by guanosine quartet structures. Biochemistry 43:13762-13771 (1996).
-
(1996)
Biochemistry
, vol.43
, pp. 13762-13771
-
-
Mazumder, A.1
Neamati, N.2
Ojwang, J.O.3
Sunder, S.4
Rando, R.F.5
Pommier, Y.6
|