-
1
-
-
0026459411
-
Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells
-
LaFemina, R. L., C. L. Schneider, H. L. Bobbins, P. L. Callahan, K. LeGrow, E. Roth, W. A. Schleif, and E. A. Emini. Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells. J. Virol. 66:7414-7419 (1992).
-
(1992)
J. Virol.
, vol.66
, pp. 7414-7419
-
-
LaFemina, R.L.1
Schneider, C.L.2
Bobbins, H.L.3
Callahan, P.L.4
LeGrow, K.5
Roth, E.6
Schleif, W.A.7
Emini, E.A.8
-
2
-
-
0027526591
-
Integration is essential for efficient gene expression of human immunodeficiency virus type 1
-
Sakai, H., M. Kawamura, J. Sakuragi, S. Sakuragi, R. Shibata, A. Ishimoto, N. Ono, S. Ueda, and A. Adachi. Integration is essential for efficient gene expression of human immunodeficiency virus type 1. J. Virol. 67: 1169-1174 (1993).
-
(1993)
J. Virol.
, vol.67
, pp. 1169-1174
-
-
Sakai, H.1
Kawamura, M.2
Sakuragi, J.3
Sakuragi, S.4
Shibata, R.5
Ishimoto, A.6
Ono, N.7
Ueda, S.8
Adachi, A.9
-
3
-
-
0028006533
-
Genetic analysis of the human immunodeficiency virus type 1 integrase protein
-
Shin, C. G., B. Taddeo, W. A. Haseltine, and C. M. Farnet. Genetic analysis of the human immunodeficiency virus type 1 integrase protein. J. Virol. 68:1633-1642 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 1633-1642
-
-
Shin, C.G.1
Taddeo, B.2
Haseltine, W.A.3
Farnet, C.M.4
-
4
-
-
0028914179
-
Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1
-
Englund, G., T. S. Theodore, E. O. Freed, A. Engleman, and M. A. Martin. Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1. J. Virol. 69:3216-3219 (1995).
-
(1995)
J. Virol.
, vol.69
, pp. 3216-3219
-
-
Englund, G.1
Theodore, T.S.2
Freed, E.O.3
Engleman, A.4
Martin, M.A.5
-
5
-
-
0028915128
-
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
-
Engleman, A., G. Englund, J. M. Orenstein, M. A. Martin, and R. Craigie. Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J. Virol. 69:2729-2736 (1995).
-
(1995)
J. Virol.
, vol.69
, pp. 2729-2736
-
-
Engleman, A.1
Englund, G.2
Orenstein, J.M.3
Martin, M.A.4
Craigie, R.5
-
6
-
-
0025001940
-
Analysis of mutations in the integration function of Moloney murine leukemia virus: Effect on DNA binding and cutting
-
Roth, M. J., P. Schwartzberg, N. Tanese, and S. P. Goff. Analysis of mutations in the integration function of Moloney murine leukemia virus: effect on DNA binding and cutting. J. Virol. 64:4709-4717 (1990).
-
(1990)
J. Virol.
, vol.64
, pp. 4709-4717
-
-
Roth, M.J.1
Schwartzberg, P.2
Tanese, N.3
Goff, S.P.4
-
7
-
-
0028239060
-
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells
-
Heinzinger, N. K., M. I. Bukrinsky, S. A. Haggerty, A. M. Ragland, V. Kewalramani, M.-A. Lee, H. Gendelman, L. Ratner, M. Stevenson, and M. Emerman. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proc. Natl. Acad. Sci. USA 91:7311-7315 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7311-7315
-
-
Heinzinger, N.K.1
Bukrinsky, M.I.2
Haggerty, S.A.3
Ragland, A.M.4
Kewalramani, V.5
Lee, M.-A.6
Gendelman, H.7
Ratner, L.8
Stevenson, M.9
Emerman, M.10
-
8
-
-
0027199982
-
Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection
-
Bukrinsky, M. I., N. Sharova, T. L. McDonald, T. Pushkarskaya, W. G. Tarpley, and M. Stevenson. Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection. Proc. Natl. Acad. Sci. USA 90: 6125-6129 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6125-6129
-
-
Bukrinsky, M.I.1
Sharova, N.2
McDonald, T.L.3
Pushkarskaya, T.4
Tarpley, W.G.5
Stevenson, M.6
-
9
-
-
0024654338
-
A nucleoprotein complex mediates the integration of retroviral DNA
-
Bowerman, B., P. O. Brown, J. M. Bishop, and H. E. Varmus. A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev. 3:469-478 (1989).
-
(1989)
Genes Dev.
, vol.3
, pp. 469-478
-
-
Bowerman, B.1
Brown, P.O.2
Bishop, J.M.3
Varmus, H.E.4
-
10
-
-
0026035178
-
Retroviral integrase domains: DNA binding and the recognition of LTR sequences
-
Kahn, E., J. P. G. Mack, R. A. Katz, J. Kulkosky, and A. M. Skalka. Retroviral integrase domains: DNA binding and the recognition of LTR sequences. Nucleic Acids Res. 19:851-860 (1991).
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 851-860
-
-
Kahn, E.1
Mack, J.P.G.2
Katz, R.A.3
Kulkosky, J.4
Skalka, A.M.5
-
11
-
-
2642604727
-
Computer analysis of retroviral pol genes: Assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes
-
Johnson, M. S., M. A. McClure, D.-F. Feng, J. Gray, and R. F. Doolittle. Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes. Proc. Natl. Acad. Sci. USA 83:7648-7652 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 7648-7652
-
-
Johnson, M.S.1
McClure, M.A.2
Feng, D.-F.3
Gray, J.4
Doolittle, R.F.5
-
12
-
-
0027456715
-
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
-
Bushman, F. D., A. Engelman, I. Palmer, P. Wingfield, and R. Craigie. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc. Natl. Acad. Sci. USA 90:3428-3432 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3428-3432
-
-
Bushman, F.D.1
Engelman, A.2
Palmer, I.3
Wingfield, P.4
Craigie, R.5
-
13
-
-
0028584269
-
Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases
-
Dyda, F., A. B. Hickman, T. M. Jenkins, A. Engelman, R. Craigie, and D. R. Davies. Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science (Washington D. C.) 266:1981-1986 (1994).
-
(1994)
Science (Washington D. C.)
, vol.266
, pp. 1981-1986
-
-
Dyda, F.1
Hickman, A.B.2
Jenkins, T.M.3
Engelman, A.4
Craigie, R.5
Davies, D.R.6
-
14
-
-
0026719238
-
Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases
-
Kulkosky, J., K. S. Jones, R. A. Katz, J. P. G. Mack, and A. M. Skalka. Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Mol. Cell. Biol. 12:2331-2338 (1992).
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2331-2338
-
-
Kulkosky, J.1
Jones, K.S.2
Katz, R.A.3
Mack, J.P.G.4
Skalka, A.M.5
-
15
-
-
0026649557
-
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
-
Engelman, A., and R. Craigie. Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J. Virol. 66:6361-6369 (1992).
-
(1992)
J. Virol.
, vol.66
, pp. 6361-6369
-
-
Engelman, A.1
Craigie, R.2
-
16
-
-
0027470432
-
Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro
-
Leavitt, A. D., L. Shiue, and H. E. Varmus. Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. J. Biol. Chem. 268:2113-2119 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2113-2119
-
-
Leavitt, A.D.1
Shiue, L.2
Varmus, H.E.3
-
17
-
-
0027210608
-
Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein
-
Vink, C., A. M. Oude Groeneger, and R. H. Plasterk. Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein. Nucleic Acids Res. 21:1419-1425 (1993).
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 1419-1425
-
-
Vink, C.1
Oude Groeneger, A.M.2
Plasterk, R.H.3
-
18
-
-
0025255158
-
Zinc fingers and other metal-binding domains
-
Berg, J. M. Zinc fingers and other metal-binding domains. J. Biol. Chem. 265:6513-6516 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 6513-6516
-
-
Berg, J.M.1
-
19
-
-
0027472085
-
Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations
-
Vincent, K. A., V. Ellison, S. A. Chow, and P. O. Brown. Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations. J. Virol. 67:425-437 (1993).
-
(1993)
J. Virol.
, vol.67
, pp. 425-437
-
-
Vincent, K.A.1
Ellison, V.2
Chow, S.A.3
Brown, P.O.4
-
20
-
-
0028239062
-
A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro
-
Ellison, V., and P. O. Brown. A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proc. Natl. Acad. Sci. USA 91:7316-7320 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7316-7320
-
-
Ellison, V.1
Brown, P.O.2
-
21
-
-
0026539155
-
Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein
-
Woerner, A. M., M. Klutch, J. G. Levin, and C. J. Marcus-Sekura. Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein. AIDS Res. Hum. Retroviruses 8:297-304 (1992).
-
(1992)
AIDS Res. Hum. Retroviruses
, vol.8
, pp. 297-304
-
-
Woerner, A.M.1
Klutch, M.2
Levin, J.G.3
Marcus-Sekura, C.J.4
-
22
-
-
0028067324
-
The core and carboxylterminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding
-
Engelman, A., A. B. Hickman, and R. Craigie. The core and carboxylterminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. J. Virol. 68:5911-5917 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 5911-5917
-
-
Engelman, A.1
Hickman, A.B.2
Craigie, R.3
-
23
-
-
0027102597
-
Genetics of retroviral integration
-
Goff, S. P. Genetics of retroviral integration. Annu. Rev. Genet. 26:527-544 (1992).
-
(1992)
Annu. Rev. Genet.
, vol.26
, pp. 527-544
-
-
Goff, S.P.1
-
24
-
-
0027973067
-
Biophysical and enzymatic properties of the catalytic domain of HIV-1 integrase
-
Hickman, A. B., I. Palmer, A. Engelman, R. Craigie, and P. Wingfield. Biophysical and enzymatic properties of the catalytic domain of HIV-1 integrase. J. Biol. Chem. 269:29279-29287 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29279-29287
-
-
Hickman, A.B.1
Palmer, I.2
Engelman, A.3
Craigie, R.4
Wingfield, P.5
-
25
-
-
0027457192
-
Inhibitors of human immunodeficiency virus integrase
-
Fesen, M. R., K. W. Kohn, F. Leteurtre, and Y. Pommier. Inhibitors of human immunodeficiency virus integrase. Proc. Natl. Acad. Sci. USA 90:2399-2403 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2399-2403
-
-
Fesen, M.R.1
Kohn, K.W.2
Leteurtre, F.3
Pommier, Y.4
-
26
-
-
0028070994
-
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds
-
Fesen, M. R., Y. Pommier, F. Leteurtre, S. Hiroguchi, J. Yung, and K. W. Kohn. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem. Pharmacol. 48:595-608 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 595-608
-
-
Fesen, M.R.1
Pommier, Y.2
Leteurtre, F.3
Hiroguchi, S.4
Yung, J.5
Kohn, K.W.6
-
27
-
-
0029065930
-
Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase
-
Cushman, M., W. M. Golebiewski, Y. Pommier, A. Mazumder, D. Reymen, E. De Clercq, L. Graham, and W. G. Rice. Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase. J. Med. Chem. 38:443-452 (1995).
-
(1995)
J. Med. Chem.
, vol.38
, pp. 443-452
-
-
Cushman, M.1
Golebiewski, W.M.2
Pommier, Y.3
Mazumder, A.4
Reymen, D.5
De Clercq, E.6
Graham, L.7
Rice, W.G.8
-
28
-
-
0026659014
-
Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions
-
Cushman, M., and P. Sherman. Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions. Biochem. Biophys. Res. Commun. 185:85-90 (1992).
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.185
, pp. 85-90
-
-
Cushman, M.1
Sherman, P.2
-
29
-
-
0028798026
-
Inhibition of human immunodeficiency virus integrase by bis-catechols
-
LaFemina, R. L., P. L. Graham, K. LeGrow, J. C. Hastings, A. Wolfe, S. D. Young, E. A. Emini, and D. J. Hazuda. Inhibition of human immunodeficiency virus integrase by bis-catechols. Antimicrob. Agents Chemother. 39:320-324 (1995).
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 320-324
-
-
LaFemina, R.L.1
Graham, P.L.2
LeGrow, K.3
Hastings, J.C.4
Wolfe, A.5
Young, S.D.6
Emini, E.A.7
Hazuda, D.J.8
-
30
-
-
2642685126
-
Inhibitors of HIV-1 replication that inhibit HIV integrase
-
Robinson, W. E., Jr., M. G. Reinecke, S. Abdel-Malek, Q. Jia, and S. A. Chow. Inhibitors of HIV-1 replication that inhibit HIV integrase. Proc. Natl. Acad. Sci. USA 93:6326-6331 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6326-6331
-
-
Robinson Jr., W.E.1
Reinecke, M.G.2
Abdel-Malek, S.3
Jia, Q.4
Chow, S.A.5
-
31
-
-
0000451677
-
Coffee bean dicaffeoylquinic acids
-
Clifford, M. N. Coffee bean dicaffeoylquinic acids. Phytochemistry 25: 1767-1769 (1986).
-
(1986)
Phytochemistry
, vol.25
, pp. 1767-1769
-
-
Clifford, M.N.1
-
32
-
-
0023907054
-
Evaluation of antiviral drugs and neutralizing antibodies against human immunodeficiency virus by a rapid and sensitive microtiter infection assay
-
Montefiori, D. C., W. E. Robinson, Jr., S. S. Schuffman, and W. M. Mitchell. Evaluation of antiviral drugs and neutralizing antibodies against human immunodeficiency virus by a rapid and sensitive microtiter infection assay. J. Clin. Microbiol. 26:231-235 (1988).
-
(1988)
J. Clin. Microbiol.
, vol.26
, pp. 231-235
-
-
Montefiori, D.C.1
Robinson Jr., W.E.2
Schuffman, S.S.3
Mitchell, W.M.4
-
33
-
-
0003047845
-
Di-E-caffeoylmeso-tartaric acid in the barren sprouts of Equisetum arvense
-
Veit, M., D. Strack, F.-C. Czygan, V. Wray, and L. Witte. Di-E-caffeoylmeso-tartaric acid in the barren sprouts of Equisetum arvense. Phytochemistry 30:527-529 (1991).
-
(1991)
Phytochemistry
, vol.30
, pp. 527-529
-
-
Veit, M.1
Strack, D.2
Czygan, F.-C.3
Wray, V.4
Witte, L.5
-
34
-
-
0000668078
-
Malonated flavonol glycosides and 3,5-dicaffeoylquinic acid from pears
-
Wald, B., V. Wray, R. Galensa, and K. Hermann. Malonated flavonol glycosides and 3,5-dicaffeoylquinic acid from pears. Phytochemistry 28: 663-665 (1989).
-
(1989)
Phytochemistry
, vol.28
, pp. 663-665
-
-
Wald, B.1
Wray, V.2
Galensa, R.3
Hermann, K.4
-
35
-
-
0026549933
-
Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus
-
Chow, S. A., K. A. Vincent, V. Ellison, and P. O. Brown. Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus. Science (Washington D. C.) 255:723-726 (1992).
-
(1992)
Science (Washington D. C.)
, vol.255
, pp. 723-726
-
-
Chow, S.A.1
Vincent, K.A.2
Ellison, V.3
Brown, P.O.4
-
36
-
-
0000615669
-
Function minimization by conjugate gradients
-
Fletcher, R., and C. M. Reeves. Function minimization by conjugate gradients. Comput. J. 7:149-154 (1964).
-
(1964)
Comput. J.
, vol.7
, pp. 149-154
-
-
Fletcher, R.1
Reeves, C.M.2
-
37
-
-
3242889085
-
HIV gp120 docking interactions and inhibitor design based on an atomic structure derived by molecular modeling using the Dreiding II force field
-
(H. Bohr and S. Brunak, eds.). CRC Press, Boca Raton, FL
-
Gabriel, J. L., and W. M. Mitchell. HIV gp120 docking interactions and inhibitor design based on an atomic structure derived by molecular modeling using the Dreiding II force field., in Protein Folds: A Distance Based Approach (H. Bohr and S. Brunak, eds.). CRC Press, Boca Raton, FL, 294-307 (1996).
-
(1996)
Protein Folds: A Distance Based Approach
, pp. 294-307
-
-
Gabriel, J.L.1
Mitchell, W.M.2
-
38
-
-
0027266977
-
Proposed atomic structure of a truncated human immunodeficiency virus glycoprotein gp120 derived by molecular modeling: Target CD4 recognition and docking mechanism
-
Gabriel, J. L., and W. M. Mitchell. Proposed atomic structure of a truncated human immunodeficiency virus glycoprotein gp120 derived by molecular modeling: target CD4 recognition and docking mechanism. Proc. Natl. Acad. Sci. USA 90:4186-4190 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4186-4190
-
-
Gabriel, J.L.1
Mitchell, W.M.2
-
39
-
-
0030479015
-
+ target cells: A molecular model of gp120 predicts ligand binding
-
in press
-
+ target cells: a molecular model of gp120 predicts ligand binding. Drug Des. Disc., in press (1996).
-
(1996)
Drug Des. Disc.
-
-
Gabriel, J.A.1
Mitchell, W.M.2
-
40
-
-
0027179416
-
Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini
-
van Gent, D. C., A. A. Oude Groeneger, and R. H. Plasterk. Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini. Nucleic Acids Res. 21:3373-3377 (1993).
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3373-3377
-
-
Van Gent, D.C.1
Oude Groeneger, A.A.2
Plasterk, R.H.3
|