Influence of subterminal viral DNA nucleotides on differential susceptibility to cleavage by human immunodeficiency virus type 1 and visna virus integrases

Journal of Virology

Volumn 70, Issue 12, 1996, Pages 9069-9073

  Katzman, Michael ^a   Sudol, Malgorzata ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; REPETITIVE DNA; VIRUS DNA;

ARTICLE; DNA CLEAVAGE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; VISNA VIRUS;

EID: 0029861955     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.12.9069-9073.1996     Document Type: Article

References (34)

1. Bushman, F. D., and R. Craigie. 1991. Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA. Proc. Natl. Acad. Sci. USA 88:1339-1343.
2. Bushman, F. D., and R. Craigie. 1992. Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites. Proc. Natl. Acad. Sci. USA 89:3458-3462.
3. Cannon, P. M., E. D. Byles, S. M. Kingsman, and A. J. Kingsman. 1996. Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication. J. Virol. 70:651-657.
4. Cannon, P. M., W. Wilson, E. Byles, S. M. Kingsman, and A. J. Kingsman. 1994. Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues. J. Virol. 68:4768-4775.
5. Cobrinik, D. A., A. Aiyar, Z. Ge, M. Katzman, H. Huang, and J. Leis. 1991. Overlapping retrovirus US sequence elements are required for efficient integration and initiation of reverse transcription. J. Virol. 65:3864-3872.
6. Craigie, R., T. Fujiwara, and F. Bushman. 1990. The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro. Cell 62:829-837.
7. Goff, S. P. 1992. Genetics of retroviral integration. Annu. Rev. Genet. 26: 527-544.
8. Katz, R. A., G. Merkel, J. Kulkosky, J. Leis, and A. M. Skalka. 1990. The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro. Cell 63:87-95.
9. Katzman, M., R. A. Katz, A. M. Skalka, and J. Leis. 1989. The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration. J. Virol. 63:5319-5327.
10. Katzman, M., and M. Sudol. 1994. In vitro activities of purified visna virus integrase. J. Virol. 68:3558-3569.
11. Katzman, M., and M. Sudol. 1995. Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases. J. Virol. 69:5687-5696.
12. Katzman, M., and M. Sudol. 1996. Nonspecific alcoholysis, a novel endonuclease activity of human immunodeficiency virus type 1 and other retroviral integrases. J. Virol. 70:2598-2604.
13. Kitamura, Y., T. Ayukawa, T. Ishikawa, T. Kanda, and K. Yoshiike. 1996. Human endogenous retrovirus K10 encodes a functional integrase. J. Virol. 70:3302-3306.
14. Kukolj, G., and A. M. Skalka. 1995. Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro. Genes Dev. 9:2556-2567.
15. Kulkosky, J., and A. M. Skalka. 1994. Molecular mechanism of retroviral DNA integration. Pharmacol. Ther. 61:185-203.
16. LaFemina, R. L., P. L. Callahan, and M. G. Cordingly. 1991. Substrate specificity of recombinant human immunodeficiency virus integrase protein. J. Virol. 65:5624-5630.
17. Leavilt, A. D., G. Robles, N. Alesandro, and H. E. Varmus. 1996. Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection. J. Virol. 70:721-728.
18. Leavitt, A. D., R. B. Rose, and H. E. Varmus. 1992. Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomycea cerevisiae. J. Virol. 66:2359-2368.
19. Lee, S. P., M. L. Censullo, H. G. Kim, and M. K. Han. 1995. Substrate-length-dependent activities of human immunodeficiency virus type 1 integrase in vitro: differential DNA binding affinities associated with different lengths of substrates. Biochemistry 34:10215-10223.
20. Masuda, T., V. Planelles, P. Krogstad, and I. S. Y. Chen. 1995. Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger domain. J. Virol. 69:6687-6696.
21. Mazumder, A., M. Gupta, and Y. Pommier. 1994. Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both extent of 3′-processing and choice of nucleophile by HIV-1 integrase. Nucleic Acids Res. 22:4441-4448.
22. Mazumder, A., and Y. Pommier. 1995. Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase. Nucleic Acids Res. 23:2865-2871.
23. Moore, S. P., M. Powers, and D. J. Garfinkel. 1995. Substrate specificity of Ty1 integrase. J. Virol. 69:4683-4692.
24. Pahl, A., and R. M. Flugel. 1993. Endonucleolytic cleavages and DNA-joining activities of the integration protein of human foamy virus. J. Virol. 67:5426-5434.
25. Reicin, A. S., G. Kalpana, S. Paik, S. Marmon, and S. Goff. 1995. Sequences in the human immunodeficiency virus type 1 U3 region required for in vivo and in vitro integration. J. Virol. 69:5904-5907.
26. Sherman, P. A., M. L. Dickson, and J. A. Fyfe. 1992. Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions. J. Virol. 66:3593-3601.
27. Sherman, P. A., and J. A. Fyfe. 1990. Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity. Proc. Natl. Acad. Sci. USA 87:5119-5123.
28. Stormann, K. D., M. C. Schlecht, and E. Pfaff. 1995. Comparative studies of bacterially expressed integrase proteins of caprine arthritis-encephalitis virus, maedi-visna virus and human immunodeficiency virus type 1. J. Gen. Virol. 76:1651-1663.
29. van den Ent, F. M. I., C. Vink, and R. H. A. Plasterk. 1994. DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein. J. Virol. 68:7825-7832.
30. Vink, C., K. H. van der Linden, and R. H. A. Plasterk. 1994. Activities of the feline immunodeficiency virus integrase protein produced in Escherichia coli. J. Virol. 68:1468-1474.
31. Vink, C., D. C. van Gent, Y. Elgersma, and R. H. A. Plasterk. 1991. Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage. J. Virol. 65:4636-4644.
32. Whitcomb, J. M., and S. H. Hughes. 1992. Retroviral reverse transcription and integration: progress and problems. Annu. Rev. Cell Biol. 8:275-306.
33. Yoshinaga, T., and T. Fujiwara. 1995. Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro. J. Virol. 69:3233-3236.
34. Yoshinaga, T., Y. Kimura-Ohtani, and T. Fujiwara. 1994. Detection and characterization of a functional complex of human immunodeficiency virus type 1 integrase and its DNA substrate by UV cross-linking. J. Virol. 68: 5690-5697.