Preorganization and protein dynamics in enzyme catalysis

Chemical Record

Volumn 2, Issue 1, 2002, Pages 24-36

  Rajagopalan, P T Ravi ^a   Benkovic, Stephen J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Dihydrofolate reductase (DHFR); Near attack conformers (NACs); Preorganization; Protein dynamics; Transition state stabilization

Indexed keywords

ALCOHOL DEHYDROGENASE; DIHYDROFLAVANOL 4 REDUCTASE; DIHYDROFLAVANOL 4-REDUCTASE; ENZYME;

BINDING SITE; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; KINETICS; METABOLISM; MOTION; PROTEIN CONFORMATION; REVIEW;

ALCOHOL OXIDOREDUCTASES; BINDING SITES; CATALYSIS; ENZYMES; KINETICS; MODELS, CHEMICAL; MOTION; PROTEIN CONFORMATION;

EID: 0002902139     PISSN: 15278999     EISSN: 15280691     Source Type: Journal    
DOI: 10.1002/tcr.10009     Document Type: Article

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