The importance of reactant positioning in enzyme catalysis: A hybrid quantum mechanics/molecular mechanics study of a haloalkane dehalogenase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 18, 2000, Pages 9937-9942

  Lau, Edmond Y ^a   Kahn, Kalju ^a   Bash, Paul A ^b   Bruice, Thomas C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DICHLOROETHANE; 2 CHLOROETHANOL; ACETIC ACID; ASPARTIC ACID; CHLORIDE; DEHALOGENASE; HYDROLASE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEHALOGENATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; GAS; NONHUMAN; PRIORITY JOURNAL; QUANTUM MECHANICS; XANTHOBACTER;

BACTERIA (MICROORGANISMS); XANTHOBACTER; XANTHOBACTER AUTOTROPHICUS;

EID: 0034730181     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.18.9937     Document Type: Article

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