메뉴 건너뛰기




Volumn 2, Issue 12, 1999, Pages 1302-1312

Growth hormone secretagogues

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0000820911     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (72)
  • 1
    • 0025787687 scopus 로고    scopus 로고
    • Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men
    • (1991) 1081-1088.
    • Iranmanesh A, Lizarralde G, Veldhuis JD: Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. J Clin Endocrinol Metab (1991) 73:1081-1088.
    • J Clin Endocrinol Metab , pp. 73
    • Iranmanesh, A.1    Lizarralde, G.2    Veldhuis, J.D.3
  • 3
    • 0021322884 scopus 로고    scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • (1984) 1537-1545.
    • Bowers CY, Momany FA, Reynolds GA, Hong A: On the In vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology (1984) 114:1537-1545.
    • Endocrinology , pp. 114
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 4
    • 0021368643 scopus 로고    scopus 로고
    • Conformational energy studies and in vitro and in vivo activity data on growth hormone-releasing peptides
    • (1984) 1531 -1536.
    • Momany FA, Bowers CY, Reynolds GA, Hong A, Newlander K: Conformational energy studies and in vitro and In vivo activity data on growth hormone-releasing peptides. Endocrinology (1984) 114:1531 -1536.
    • Endocrinology , pp. 114
    • Momany, F.A.1    Bowers, C.Y.2    Reynolds, G.A.3    Hong, A.4    Newlander, K.5
  • 5
    • 0032444392 scopus 로고    scopus 로고
    • Growth hormone-releasing peptide (CHRP). C
    • (1998) 1316-1329.
    • Bowers CY: Growth hormone-releasing peptide (CHRP). Cell Mol Life Sei (1998) 54:1316-1329.
    • Ell Mol Life Sei , pp. 54
    • Bowers, C.Y.1
  • 6
    • 0033015380 scopus 로고    scopus 로고
    • A new orphan receptor involved in pulsatile growth hormone release
    • (1999) 128-135.
    • Smith RG, Feighner ,S; Prendergast K, Guan X, Howard A: A new orphan receptor involved In pulsatile growth hormone release. -Trends Endocrinol Metab (1999) 10:128-135.
    • Trends Endocrinol Metab , pp. 10
    • Feighner, S.R.G.1
  • 7
    • 0031979460 scopus 로고    scopus 로고
    • Orally active growth hormone secretagogues: State of the art and clinical perspectives. A
    • Ghlgo E, Arvat E, Camanni F: Orally active growth hormone secretagogues: state of the art and clinical perspectives. Ann Med (Helsinki) (1998) 30:159-168.
    • (1998) Nn Med (Helsinki) , vol.30 , pp. 159-168
    • Ghlgo, E.1    Arvat, E.2    Camanni, F.3
  • 11
    • 0025790152 scopus 로고    scopus 로고
    • Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-WheLys-NH2-induced growth hormone release from rat primary pituitary cells
    • (1991) 3337-3342.
    • Cheng K, Chan WWS, Butler B, Barretto A, Smith RG: Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-WheLys-NH2-induced growth hormone release from rat primary pituitary cells. Endocrinology (1991) 129:3337-3342.
    • Endocrinology , pp. 129
    • Cheng, K.1    Wws, C.2    Butler, B.3    Barretto, A.4    Smith, R.G.5
  • 12
    • 0027414444 scopus 로고    scopus 로고
    • Systemic administration of growth hormone-releasing peptide activates hypothalamic arcuate neurons
    • (1993)
    • Dickson SL, Leng G, Robinson ICAF: Systemic administration of growth hormone-releasing peptide activates hypothalamic arcuate neurons. Neuroscience (1993)53:303-306.
    • Neuroscience , pp. 303-306
    • Dickson, S.L.1    Leng, G.2    Robinson, I.3
  • 13
    • 0031951257 scopus 로고    scopus 로고
    • The nonpeptide growth hormone secretagogue, MK-0677, activates hypothalamic arcuate nucleus neurons
    • (1998)
    • Bailey ART, Smith RG, Leng G: The nonpeptide growth hormone secretagogue, MK-0677, activates hypothalamic arcuate nucleus neurons in vivo. J Neuroendocrinol (1998) 10:111-118.
    • In Vivo. J Neuroendocrinol , pp. 111-118
    • Art, B.1    Smith, R.G.2    Leng, G.3
  • 16
    • 0024453883 scopus 로고    scopus 로고
    • The effects of a growth hormone-releasing peptide and growth hormone-releasing factor in conscious and anesthetized rats
    • (1989)
    • Clark RG, Cartsson LMS, Trojnar J, Robinson 1C: The effects of a growth hormone-releasing peptide and growth hormone-releasing factor in conscious and anesthetized rats. J Neuroendocrinol (1989) 1:249-55.
    • J Neuroendocrinol , pp. 249-55
    • Clark, R.G.1    Lms, C.2    Trojnar, J.3    Robinson, C.4
  • 17
    • 0031732737 scopus 로고    scopus 로고
    • Growth hormone (GH)-Releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation
    • (1998)
    • Pandya N, Demott-Friberg R, Bowers CY, Barkan AI, Jaffe CA: Growth hormone (GH)-Releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation. J Clin Endocrinol Metab (1998) 83:1186-1189.
    • J Clin Endocrinol Metab , pp. 1186-1189
    • Pandya, N.1    Demott-Friberg, R.2    Bowers, C.Y.3    Barkan, A.I.4    Jaffe, C.A.5
  • 18
    • 0033032864 scopus 로고    scopus 로고
    • Selective lack of growth hormone (GH) response to the GH-releasing peptide hexarelin in patients with GH-releasing hormone receptor deficiency
    • (1999)
    • Maheshwari HG, Rahim A, Shalet SM, Baumann G: Selective lack of growth hormone (GH) response to the GH-releasing peptide hexarelin In patients with GH-releasing hormone receptor deficiency. J Clin Endocrinol Metab (1999) 84: 956-959.
    • J Clin Endocrinol Metab , pp. 956-959
    • Maheshwari, H.G.1    Rahim, A.2    Shalet, S.M.3    Baumann, G.4
  • 19
    • 0028807113 scopus 로고    scopus 로고
    • Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transaction
    • (1995)
    • Pombo M, Barreiro J, Penalva A, Peino R, Dieguez C, Casanueva FF: Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transaction. J Clin Endocrinol Metab (1995) 80:180-184.
    • J Clin Endocrinol Metab , pp. 180-184
    • Pombo, M.1    Barreiro, J.2    Penalva, A.3    Peino, R.4    Dieguez, C.5    Casanueva, F.F.6
  • 20
    • 0026607276 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. e
    • (1992)
    • Goth Ml, Lyons CE, Canny BJ, Thomer MO: Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology (1992) 130:939-944.
    • Ndocrinology , pp. 939-944
    • Ml, G.1    Lyons, C.E.2    Canny, B.J.3    Thomer, M.O.4
  • 22
    • 0027944106 scopus 로고    scopus 로고
    • Effects of acute and repeated intravenous administration of L-692585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles
    • (1994)
    • Jacks T, Hickey G, Judith F, Taylor J, Chen H, Krupa D, Feeney W, Schoen W, Ok D, Fisher M, Wyvratt M, Smith R: Effects of acute and repeated intravenous administration of L-692585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles. J Endocrinol (1994) 143:399-406.
    • J Endocrinol , pp. 399-406
    • Jacks, T.1    Hickey, G.2    Judith, F.3    Taylor, J.4    Chen, H.5    Krupa, D.6    Feeney, W.7    Schoen, W.8    Ok, D.9    Fisher, M.10    Wyvratt, M.11    Smith, R.12
  • 23
    • 0031757867 scopus 로고    scopus 로고
    • A five day treatment with daily subcutaneous injections of growth hormone-releasing peptide-2 causes response attenuation and does not stimulate insulin-like growth factor-! secretion in healthy young men
    • (1998)
    • Nijland EA, Strasburger CJ, Popp-Snijders C, Van Der Wal PS, van der Veen EA: A five day treatment with daily subcutaneous injections of growth hormone-releasing peptide-2 causes response attenuation and does not stimulate insulin-like growth factor-! secretion in healthy young men. Eur J Endocrinol (1998) 139:395-401.
    • Eur J Endocrinol , pp. 395-401
    • Nijland, E.A.1    Strasburger, C.J.2    Popp-Snijders, C.3    Van Der Wal, P.S.4    Van Der Veen, E.A.5
  • 25
    • 0030852329 scopus 로고    scopus 로고
    • Effects of GHRP-2 and Hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH
    • (1997)
    • Arvat E, Di Vito L, Maccagno B, Broglio F, Boghen F, Deghenghi R, Camanni F, Ghigo E: Effects of GHRP-2 and Hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH. Peptides (1997) 18:885-891.
    • Peptides , pp. 885-891
    • Arvat, E.1    Di Vito, L.2    Maccagno, B.3    Broglio, F.4    Boghen, F.5    Deghenghi, R.6    Camanni, F.7    Ghigo, E.8
  • 26
    • 0029845438 scopus 로고    scopus 로고
    • Hexarelin-induced growth hormone, cortisol, and prolactin release: A doseresponse study
    • (1996)
    • Massoud AF, Hindmarsh PC, Brook CGD: Hexarelin-induced growth hormone, cortisol, and prolactin release: a doseresponse study. J Clin Endocrinol Metab (1996) 81:4338-4341.
    • J Clin Endocrinol Metab , pp. 4338-4341
    • Massoud, A.F.1    Hindmarsh, P.C.2    Brook, C.G.D.3
  • 27
    • 0030909925 scopus 로고    scopus 로고
    • Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, in rats
    • (1997)
    • Thomas GB, Fairhall KM, Robinson ICAF: Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, In rats. Endocrinology (1997) 138:1585-1591.
    • Endocrinology , pp. 1585-1591
    • Thomas, G.B.1    Fairhall, K.M.2    Icaf, R.3
  • 28
    • 0032462760 scopus 로고    scopus 로고
    • Growth hormone Secretagogues as corticotropin-releasing factors
    • (1998) (Suppl B):145-148. '
    • Ghigo E, Arvat E, Camanni F: Growth hormone Secretagogues as corticotropin-releasing factors. Growth Horm IGF Res (1998) 8(Suppl B):145-148. '
    • Growth Horm IGF Res , pp. 8
    • Ghigo, E.1    Arvat, E.2    Camanni, F.3
  • 32
    • 0029769726 scopus 로고    scopus 로고
    • The role of growth hormone in the regulation of body composition in the adult
    • (1996)
    • Russell-Jones DL, Weissberger AJ: The role of growth hormone in the regulation of body composition in the adult. Growth flegu/(1996) 6:247-252.
    • Growth Flegu , pp. 247-252
    • Weissberger Aj, R.D.L.1
  • 36
    • 0030630255 scopus 로고    scopus 로고
    • Growth hormone, skin and wound healing experimental studies in the rat
    • (1997) (Suppl):1 -54.
    • Jorgensen PH: Growth hormone, skin and wound healing experimental studies in the rat. Acta Pathol Microbiol Immunol Scand (1997) 72(Suppl):1 -54.
    • Acta Pathol Microbiol Immunol Scand , pp. 72
    • Jorgensen, P.H.1
  • 38
    • 0029993686 scopus 로고    scopus 로고
    • Growth hormone replacement in healthy older men improves body composition but not functional ability
    • (1996)
    • Papadakis MA, Grady D, Black D, Tiemey MJ, Gooding GAW, Schambelan M, Grunfeld C: Growth hormone replacement in healthy older men improves body composition but not functional ability. Ann Intern Med (1996) 124:708-716.
    • Ann Intern Med , pp. 708-716
    • Ma, P.1    Grady, D.2    Black, D.3    Tiemey, M.J.4    Gaw, G.5    Schambelan, M.6    Grunfeld, C.7
  • 40
    • 8044227232 scopus 로고    scopus 로고
    • MK0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles
    • (1996)
    • Jacks T, Smith R, Judith F, Schleim K, Frazier E, Chen H, Krupa D, Hora Jr D, Nargund R, Patchett A, Hickey G: MK0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles. Endocrinology (1996) 137:5284-5289.
    • Endocrinology , pp. 5284-5289
    • Jacks, T.1    Smith, R.2    Judith, F.3    Schleim, K.4    Frazier, E.5    Chen, H.6    Krupa, D.7    Nargund, R.8    Patchett, A.9    Hickey, G.10
  • 55
    • 0029809414 scopus 로고    scopus 로고
    • Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692429, in older adults - A clinical research center study
    • (1996)
    • Chapman IM, Hartman ML, Pezzoli SS, Thomer MO: Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692429, in older adults - A clinical research center study. J Clin Endocrinol Metab (1996) 81:2874-2880.
    • J Clin Endocrinol Metab , pp. 2874-2880
    • Chapman, I.M.1    Hartman, M.L.2    Pezzoli, S.S.3    Thomer, M.O.4
  • 57
    • 0027180817 scopus 로고    scopus 로고
    • GH releasing peptides-structure and kinetics
    • (1993)
    • Bowers CY: GH releasing peptides-structure and kinetics. J Pediatr Endocrinol (1993) 6:21-31.
    • J Pediatr Endocrinol , pp. 21-31
    • Bowers, C.Y.1
  • 58
    • 0031762361 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: A phase i study in children
    • (1998) 1168-1172.
    • Pihoker C, Keams GL, French D, Bowers CY: Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: a phase I study In children. J Clin Endocrinol Metab (1998) 83:1168-1172.
    • J Clin Endocrinol Metab , pp. 83
    • Pihoker, C.1    Keams, G.L.2    French, D.3    Bowers, C.Y.4
  • 59
    • 0031759899 scopus 로고    scopus 로고
    • Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children
    • (1998) 2355-2360.
    • Mericq V, Cassorta F, Salazar T, Avila A, Iniguez G, Bowers CY, Merriam GR: Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children. J Clin Endocrinol Metab (1998) 83: 2355-2360.
    • J Clin Endocrinol Metab , pp. 83
    • Mericq, V.1    Cassorta, F.2    Salazar, T.3    Avila, A.4    Iniguez, G.5    Bowers, C.Y.6    Merriam, G.R.7
  • 60
    • 0028133892 scopus 로고    scopus 로고
    • Hexarelin His-D-2-Methyl-Trp-Ala-Trp-DPhe-Lys-NHJ, a new GH-releasing peptide, is biologically active in male and female rats
    • (1994)
    • Conley LK, Giustina A, Imbimbo BP, Stagg LC, Deghenghi R, Wehrenberg WB: Hexarelin [His-D-2-Methyl-Trp-Ala-Trp-DPhe-Lys-NHJ, a new GH-releasing peptide, is biologically active in male and female rats. Endocrine (1994) 2:691-695.
    • Endocrine , pp. 691-695
    • Conley, L.K.1    Giustina, A.2    Imbimbo, B.P.3    Stagg, L.C.4    Deghenghi, R.5    Wehrenberg, W.B.6
  • 61
    • 0031662260 scopus 로고    scopus 로고
    • Hexarelin, a synthetic GHreleasing peptide, is a powerful stimulus of GH secretion in pubertal children and in adults but not in prepubertal children and in elderly subjects
    • (1998)
    • Bellone J, Bartolotta, E, Sgattoni C, Aimaretti G, Arvat E, Bellone S, Deghenghi R, Ghigo E: Hexarelin, a synthetic GHreleasing peptide, is a powerful stimulus of GH secretion in pubertal children and in adults but not In prepubertal children and in elderly subjects. J Endocrinol Invest (1998) 21:494-500.
    • J Endocrinol Invest , pp. 494-500
    • Bellone, J.1    Bartolotta2    Sgattoni, C.3    Aimaretti, G.4    Arvat, E.5    Bellone, S.6    Deghenghi, R.7    Ghigo, E.8
  • 62
    • 0031724499 scopus 로고    scopus 로고
    • Growth hormone status during long-term hexarelin therapy
    • (1998) 1644-1649.
    • Rahim A, O'Neill PA, Shalet SM: Growth hormone status during long-term hexarelin therapy. J Clin Endocrinol Metab (1998)83:1644-1649.
    • J Clin Endocrinol Metab , pp. 83
    • Rahim, A.1    O'Neill, P.A.2    Shalet, S.M.3
  • 68
    • 7344221463 scopus 로고    scopus 로고
    • 1 -[2(RH2-Amino-2-methylpropionylamino)-3-{1 H-indol-3ylpropionyl]-3-benzylpiperidine-3(S)-carboxylic acid ethyl ester (L-163,540): A potent, orally bioavailable, and shortduration growth hormone secretagogue
    • (1998) 2439-2441.
    • Yang L, Morriello G, Patchett AA, Leung K, Jacks T, Cheng K, Schleim KD, Feeney W, Chan, WW-S, Chiu S-HL, Smith RG: 1 -[2(RH2-Amino-2-methylpropionylamino)-3-{1 H-indol-3yl)propionyl]-3-benzylpiperidine-3(S)-carboxylic acid ethyl ester (L-163,540): a potent, orally bioavailable, and shortduration growth hormone secretagogue. J Med Chem (1998)41:2439-2441.
    • J Med Chem , pp. 41
    • Yang, L.1    Morriello, G.2    Patchett, A.A.3    Leung, K.4    Jacks, T.5    Cheng, K.6    Schleim, K.D.7    Feeney, W.8    Chan9    Chiu, S.-H.L.10    Smith, R.G.11
  • 71
    • 33747131207 scopus 로고    scopus 로고
    • ELI LILLY AND COMPANY (Kauffman R, Palkowitz A): Treatment of congestive heart failure with growth hormone secretagogues. WO-09908697 (1999).
  • 72
    • 33747095213 scopus 로고    scopus 로고
    • KAKEN PHARMACEUTICAL Co LTD (Funamazi H, Ishiyama N): Novel amide derivatives and their use as growth hormone releasing factors. WO-09909991 (1999).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.