메뉴 건너뛰기




Volumn 43, Issue 5, 1995, Pages 631-635

Intranasal administration of the GHRP hexarelin accelerates growth in short children

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; GONADORELIN DERIVATIVE; HEXARELIN; SOMATOMEDIN C;

EID: 0028884562     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2265.1995.tb02929.x     Document Type: Article
Times cited : (76)

References (31)
  • 2
    • 0027495143 scopus 로고
    • The growth hormone (GH) response to GH‐releasing peptide (His‐D‐Trp‐Ala‐Trp‐D‐Phe‐Lys‐NH2, GH‐releasing hormone, and thyrotropin‐releasing hormone in acromegaly
    • Alster, D.L., Bowers, C.Y., Jaffe, C.A., Ho, P.J. & Barkan, A.L. (1993) The growth hormone (GH) response to GH‐releasing peptide (His‐D‐Trp‐Ala‐Trp‐D‐Phe‐Lys‐NH 2, GH‐releasing hormone, and thyrotropin‐releasing hormone in acromegaly. Journal of Clinical Endocrinology and Metabolism, 11, 842–845.
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.11 , pp. 842-845
    • Alster, D.L.1    Bowers, C.Y.2    Jaffe, C.A.3    Ho, P.J.4    Barkan, A.L.5
  • 3
    • 84895265131 scopus 로고
    • Is short stature a handicap‐legal and rehabilitation aspects, in: Limb Lengthening‐For Whom, When and How?
    • Aran, O., Laron, Z., Galatzer, A., Nagelberg, N. & Rubicsek, Y. (1995) Is short stature a handicap‐legal and rehabilitation aspects. In Limb Lengthening‐For Whom, When and How? (eds Z. Laron, S. Mastragostino, C. Romano, A. Cohen & S. Boero), pp. 131–135. Freund Publishing House Ltd., London‐Tel Aviv.
    • (1995) , pp. 131-135
    • Aran, O.1    Laron, Z.2    Galatzer, A.3    Nagelberg, N.4    Rubicsek, Y.5
  • 4
    • 0027180817 scopus 로고
    • GH releasing peptides‐structure and kinetics
    • Bowers, C.Y. (1993) GH releasing peptides‐structure and kinetics. Journal of Pediatric Endocrinolology, 6, 21–31.
    • (1993) Journal of Pediatric Endocrinolology , vol.6 , pp. 21-31
    • Bowers, C.Y.1
  • 5
    • 0026534533 scopus 로고
    • The growth hormone‐releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration
    • Bowers, C.Y., Alster, D.K. & Frentz, J.M. (1992) The growth hormone‐releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration. Journal of Clinical Endocrinology and Metabolism, 14, 292–298.
    • (1992) Journal of Clinical Endocrinology and Metabolism , vol.14 , pp. 292-298
    • Bowers, C.Y.1    Alster, D.K.2    Frentz, J.M.3
  • 6
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic Hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers, C.Y., Momany, F.A., Reynolds, G.A. & Hong, A. (1984) On the in vitro and in vivo activity of a new synthetic Hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology, 114, 1537–1545.
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 8
    • 0024412624 scopus 로고
    • The synergistic affects of His‐o‐Trp‐Ala‐Trp‐o‐Phe‐Lys‐NH2 on intracellular adenosine 3′5′‐monophosphate accumulation in rat primary pituitary cell culture
    • Cheng, K., Chan, W.W.S., Barreto, A., Convey, E.M. & Smith, R.G. (1989) The synergistic affects of His‐o‐Trp‐Ala‐Trp‐o‐Phe‐Lys‐NH 2 on intracellular adenosine 3′5′‐monophosphate accumulation in rat primary pituitary cell culture. Endocrinology, 124, 2791–2798.
    • (1989) Endocrinology , vol.124 , pp. 2791-2798
    • Cheng, K.1    Chan, W.W.S.2    Barreto, A.3    Convey, E.M.4    Smith, R.G.5
  • 10
    • 0028208649 scopus 로고
    • GH‐releasing activity of Hexarelin, a new growth hormone releasing peptide, in infant and adult rats
    • Deghenghi, R., Canazi, M.M., Torsello, A., Battisti, C., Muller, E.E. & Locatelli, V. (1994) GH‐releasing activity of Hexarelin, a new growth hormone releasing peptide, in infant and adult rats. Life Sciences, 54, 1321–1328.
    • (1994) Life Sciences , vol.54 , pp. 1321-1328
    • Deghenghi, R.1    Canazi, M.M.2    Torsello, A.3    Battisti, C.4    Muller, E.E.5    Locatelli, V.6
  • 11
    • 0028935099 scopus 로고
    • Short term effect of intranasal administration of Hexarelin‐a synthetic growth hormone‐releasing peptide. Preliminary communication
    • Frenkel, J., Silbergeld, A., Deghenghi, R. & Laron, Z. (1995) Short term effect of intranasal administration of Hexarelin‐a synthetic growth hormone‐releasing peptide. Preliminary communication. Journal of Pediatric Endocrinology and Metabolism, 8, 43–45.
    • (1995) Journal of Pediatric Endocrinology and Metabolism , vol.8 , pp. 43-45
    • Frenkel, J.1    Silbergeld, A.2    Deghenghi, R.3    Laron, Z.4
  • 14
    • 0003556467 scopus 로고
    • Radiographic Atlas of Skeletal Development of Hand and Wrist
    • Greulich, W.W. & Pyle, S.I. (1959) Radiographic Atlas of Skeletal Development of Hand and Wrist. Stanford University Press, Stanford.
    • (1959)
    • Greulich, W.W.1    Pyle, S.I.2
  • 15
    • 0025740010 scopus 로고
    • Intranasal administration of His‐o‐Trp‐Ala‐Trp–Phe‐Lys‐NH2 (growth hormone releasing peptide) increased plasma growth hormone and insulin‐like growth factor‐I levels in normal men
    • Hayashi, S., Okimura, Y., Yagi, H., Ichiyama, T., Takeshima, Y., Shakutsui, S., Oohashi, S., Bowers, C.Y. & Chihara, K. (1991) Intranasal administration of His‐o‐Trp‐Ala‐Trp–Phe‐Lys‐NH 2 (growth hormone releasing peptide) increased plasma growth hormone and insulin‐like growth factor‐I levels in normal men. Endocrinologia Japonica, 38, 15–21.
    • (1991) Endocrinologia Japonica , vol.38 , pp. 15-21
    • Hayashi, S.1    Okimura, Y.2    Yagi, H.3    Ichiyama, T.4    Takeshima, Y.5    Shakutsui, S.6    Oohashi, S.7    Bowers, C.Y.8    Chihara, K.9
  • 16
    • 8944222303 scopus 로고
    • Tests for hGH secretion in childhood. Comparison of response of growth hormone to insulin hypoglycemia and to arginine in children with constitutional short stature in different pubertal stages, in: Pediatric and Adolescent Endocrinology. Volume 12. Evaluation of Growth Hormone Secretion
    • Josefsberg, Z., Kauli, R., Keret, R., Brown, M., Bialik, O., Greenberg, D. & Laron, Z. (1983) Tests for hGH secretion in childhood. Comparison of response of growth hormone to insulin hypoglycemia and to arginine in children with constitutional short stature in different pubertal stages. In Pediatric and Adolescent Endocrinology. Volume 12. Evaluation of Growth Hormone Secretion (eds Z. Laron & O. Butenandt) pp. 66–74. S Barger, Basel.
    • (1983) , pp. 66-74
    • Josefsberg, Z.1    Kauli, R.2    Keret, R.3    Brown, M.4    Bialik, O.5    Greenberg, D.6    Laron, Z.7
  • 17
    • 0015793275 scopus 로고
    • Insulin secretion in children with constitutional familial short stature
    • Karp, M., Laron, Z. & Doron, M. (1973) Insulin secretion in children with constitutional familial short stature. Journal of Pediatrics, 83, 241–246.
    • (1973) Journal of Pediatrics , vol.83 , pp. 241-246
    • Karp, M.1    Laron, Z.2    Doron, M.3
  • 18
    • 0027978507 scopus 로고
    • Treatment with GHRH(1–29)NH2 in children with idiopathic short stature induces a sustained increase in growth velocity
    • Kirk, J.M.W., Trainer, P.J., Majrowski, W.H., Murphy, J., Savage, M.O. & Besser, G.M. (1994) Treatment with GHRH(1–29)NH 2 in children with idiopathic short stature induces a sustained increase in growth velocity. Clinical Endocrinology, 41, 487–493.
    • (1994) Clinical Endocrinology , vol.41 , pp. 487-493
    • Kirk, J.M.W.1    Trainer, P.J.2    Majrowski, W.H.3    Murphy, J.4    Savage, M.O.5    Besser, G.M.6
  • 19
    • 0028577366 scopus 로고
    • Renal function in Laron Syndrome patients treated by IGF‐I
    • Klinger, B. & Laron, Z. (1994) Renal function in Laron Syndrome patients treated by IGF‐I. Pediatric Nephrology, 8, 684–688.
    • (1994) Pediatric Nephrology , vol.8 , pp. 684-688
    • Klinger, B.1    Laron, Z.2
  • 20
    • 0027474089 scopus 로고
    • Somatomedin I in clinical use: facts and potential
    • Laron, Z. (1993) Somatomedin I in clinical use: facts and potential. Drugs, 45, 1–8.
    • (1993) Drugs , vol.45 , pp. 1-8
    • Laron, Z.1
  • 21
    • 0027140939 scopus 로고
    • Growth hormone‐releasing activity of growth hormone‐releasing peptide‐1 (a synthetic heptapeptide) in children and adolescents
    • Laron, Z., Bowers, C.Y., Hirsch, D., Almonte, A.S., Pelz, M., Keret, R. & Gil‐Ad, I. (1993) Growth hormone‐releasing activity of growth hormone‐releasing peptide‐1 (a synthetic heptapeptide) in children and adolescents. Acta Endocrinologica, 129, 424–426.
    • (1993) Acta Endocrinologica , vol.129 , pp. 424-426
    • Laron, Z.1    Bowers, C.Y.2    Hirsch, D.3    Almonte, A.S.4    Pelz, M.5    Keret, R.6    Gil‐Ad, I.7
  • 22
    • 0025786009 scopus 로고
    • Optimum use of growth hormone in children
    • Laron, Z. & Butenandt, O. (1991) Optimum use of growth hormone in children. Drugs, 42, 1–8.
    • (1991) Drugs , vol.42 , pp. 1-8
    • Laron, Z.1    Butenandt, O.2
  • 24
    • 85120510624 scopus 로고
    • Growth hormonereleasing peptide‐Hexarelin‐in children. Biochemical and growth promoting effects, in: Growth Hormone Secretagogues
    • Laron, Z., Frenkel, J. & Silbergeld, A. (1995) Growth hormonereleasing peptide‐Hexarelin‐in children. Biochemical and growth promoting effects. In Growth Hormone Secretagogues (eds B.B. Bercu & R.F. Walker) Springer Verlag, New York (in press).
    • (1995)
    • Laron, Z.1    Frenkel, J.2    Silbergeld, A.3
  • 25
    • 0028034580 scopus 로고
    • IGF‐I treatment of adult patients with Laron Syndrome: preliminary results
    • Laron, Z. & Klinger, B. (1994) IGF‐I treatment of adult patients with Laron Syndrome: preliminary results. Clinical Endocrinology, 41, 631–638.
    • (1994) Clinical Endocrinology , vol.41 , pp. 631-638
    • Laron, Z.1    Klinger, B.2
  • 26
    • 0025837933 scopus 로고
    • Biochemical and hormonal changes induced by one week of administration of rIGF‐I to patients with Laron type dwarfism
    • Laron, Z., Klinger, B., Jensen, L.T. & Erster, B. (1991) Biochemical and hormonal changes induced by one week of administration of rIGF‐I to patients with Laron type dwarfism. Clinical Endocrinology, 35, 145–150.
    • (1991) Clinical Endocrinology , vol.35 , pp. 145-150
    • Laron, Z.1    Klinger, B.2    Jensen, L.T.3    Erster, B.4
  • 27
    • 0013857766 scopus 로고
    • Measurement of human growth hormone. Description of the method and its clinical applications
    • Laron, Z. & Mannheimer, S. (1966) Measurement of human growth hormone. Description of the method and its clinical applications. Israel Journal of Medical Sciences, 2, 115–119.
    • (1966) Israel Journal of Medical Sciences , vol.2 , pp. 115-119
    • Laron, Z.1    Mannheimer, S.2
  • 28
    • 8944234077 scopus 로고
    • Oral clonidine‐a simple, safe and effective test for growth hormone secretion, in: Pediatric and Adolescent Endocrinology. Volume 12, Evaluation of Growth Hormone Secretion
    • Laron, Z., Topper, E. & Gil‐Ad, I. (1983) Oral clonidine‐a simple, safe and effective test for growth hormone secretion. In Pediatric and Adolescent Endocrinology. Volume 12, Evaluation of Growth Hormone Secretion (eds Z. Laron & O. Butenandt), pp. 103–121. S. Karger, Basel.
    • (1983) , pp. 103-121
    • Laron, Z.1    Topper, E.2    Gil‐Ad, I.3
  • 29
    • 0021368643 scopus 로고
    • Conformational energy studies and in vitro and in vivo activity data on active GH releasing peptides
    • Momany, F.A., Bowers, C.Y., Reynolds, G.A., Hong, A. & Newlander, K. (1984) Conformational energy studies and in vitro and in vivo activity data on active GH releasing peptides. Endocrinology, 114, 1531–1536.
    • (1984) Endocrinology , vol.114 , pp. 1531-1536
    • Momany, F.A.1    Bowers, C.Y.2    Reynolds, G.A.3    Hong, A.4    Newlander, K.5
  • 30
    • 0346160174 scopus 로고
    • Growth, stature and adaptation, in: Behavioral, Social and Cognitive Aspects of Growth Delay
    • Stabler, B. & Underwood, L.E. (1994) Growth, stature and adaptation. In Behavioral, Social and Cognitive Aspects of Growth Delay. University of North Carolina at Chapel Hill Press, Chapel Hill, USA.
    • (1994)
    • Stabler, B.1    Underwood, L.E.2
  • 31
    • 0013977629 scopus 로고
    • Standards from birth to maturity for height, weight, height velocity and weight velocity in British children
    • Tanner, J.M., Whitehouse, R.H. & Takaishi, M. (1966) Standards from birth to maturity for height, weight, height velocity and weight velocity in British children. Archives of Diseases in Childhood, 41, 613–635.
    • (1966) Archives of Diseases in Childhood , vol.41 , pp. 613-635
    • Tanner, J.M.1    Whitehouse, R.H.2    Takaishi, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.