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Volumn 81, Issue 8, 1996, Pages 2874-2880

Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults - A Clinical Research Center study

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 3 METHYL N [2,3,4,5 TETRAHYDRO 2 OXO 1 [[2' (1H TETRAZOL 5 YL) 1,1' BIPHENYL 4 YL]METHYL] 1H 1 BENZAZEPIN 3 YL]BUTANAMIDE; FOLLITROPIN; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; LUTEINIZING HORMONE; PROLACTIN; SERMORELIN; SOMATOMEDIN C; TESTOSTERONE;

EID: 0029809414     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.8.2874     Document Type: Article
Times cited : (61)

References (44)
  • 2
    • 0023098492 scopus 로고
    • Effects of sex and age on the 24-hour profile of growth hormone secretion in man: Importance of endogenous estradiol concentrations
    • Ho KY, Evans WS, Blizzard RM, et al. 1987 Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab. 64:51-58.
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 51-58
    • Ho, K.Y.1    Evans, W.S.2    Blizzard, R.M.3
  • 3
    • 0021928693 scopus 로고
    • The influence of age on the 24-hour integrated concentration of growth hormone in normal individuals
    • Zadik Z, Chalew SA, McCarter Jr RJ, Meistas M, Kowarski AA. 1985 The influence of age on the 24-hour integrated concentration of growth hormone in normal individuals. J Clin Endocrinol Metab. 60:513-516.
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 513-516
    • Zadik, Z.1    Chalew, S.A.2    McCarter Jr., R.J.3    Meistas, M.4    Kowarski, A.A.5
  • 4
    • 0025787687 scopus 로고
    • Age and relative adiposity are specific determinants of the frequency and amplitude of GH secretory bursts and the half-life of endogenous GH in healthy men
    • Iranmanesh A, Lizzarralde G, Veldhuis JD. 1991 Age and relative adiposity are specific determinants of the frequency and amplitude of GH secretory bursts and the half-life of endogenous GH in healthy men. J Clin Endocrinol Metab. 73:1081-1088.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 1081-1088
    • Iranmanesh, A.1    Lizzarralde, G.2    Veldhuis, J.D.3
  • 7
    • 0028864065 scopus 로고
    • The diagnosis of growth hormone deficiency (GHD) in adults
    • Thorner MO, Bengtsson BA, Ho KY, et al. 1995 The diagnosis of growth hormone deficiency (GHD) in adults [Letter]. J Clin Endocrinol Metab. 80:3097-3098.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3097-3098
    • Thorner, M.O.1    Bengtsson, B.A.2    Ho, K.Y.3
  • 8
    • 0022370713 scopus 로고
    • Growth hormone, body composition, and aging
    • Rudman D. 1985 Growth hormone, body composition, and aging [Review]. J Am Geriatr Soc. 33:800-807.
    • (1985) J Am Geriatr Soc , vol.33 , pp. 800-807
    • Rudman, D.1
  • 9
    • 0025368959 scopus 로고
    • Effects of human growth hormone in men over 60 years old
    • Rudman D, Feller AG, Nagraj HS, et al. 1990 Effects of human growth hormone in men over 60 years old. N Engl J Med. 323:1-6.
    • (1990) N Engl J Med , vol.323 , pp. 1-6
    • Rudman, D.1    Feller, A.G.2    Nagraj, H.S.3
  • 10
    • 0028146277 scopus 로고
    • Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women
    • Holloway L, Butterfield G, Hintz RL, Gesundheit N, Marcus R. 1994 Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women. J Clin Endocrinol Metab. 79:470-479.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 470-479
    • Holloway, L.1    Butterfield, G.2    Hintz, R.L.3    Gesundheit, N.4    Marcus, R.5
  • 11
    • 0028116813 scopus 로고
    • Effect of recombinant human growth hormone on the muscle strength response to resistance exercise in elderly men
    • Taaffe DR, Pruitt L, Reim J, et al. 1994 Effect of recombinant human growth hormone on the muscle strength response to resistance exercise in elderly men. J Clin Endocrinol Metab. 79:1361-1366.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1361-1366
    • Taaffe, D.R.1    Pruitt, L.2    Reim, J.3
  • 12
    • 0028900940 scopus 로고
    • Effect of growth hormone and resistance exercise on muscle growth and strength in older men
    • Yarasheski KE, Zachwieja JJ, Campbell JA, Bier DM. 1995 Effect of growth hormone and resistance exercise on muscle growth and strength in older men. Am J Physiol. 268:E268-E276.
    • (1995) Am J Physiol , vol.268
    • Yarasheski, K.E.1    Zachwieja, J.J.2    Campbell, J.A.3    Bier, D.M.4
  • 13
    • 0027429871 scopus 로고
    • Cardiovascular risk factors in adult patients with growth hormone deficiency
    • Copenh
    • Rosen T, Eden S, Larson G, Wilhelmsen L, Bengtsson BA. 1993 Cardiovascular risk factors in adult patients with growth hormone deficiency. Acta Endocrinol (Copenh). 129:195-200.
    • (1993) Acta Endocrinol , vol.129 , pp. 195-200
    • Rosen, T.1    Eden, S.2    Larson, G.3    Wilhelmsen, L.4    Bengtsson, B.A.5
  • 15
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon F, Cuneo RC, Heap R, Sonksen PH. 1989 The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med. 321:1797-1803.
    • (1989) N Engl J Med , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Heap, R.3    Sonksen, P.H.4
  • 16
    • 0027958815 scopus 로고
    • The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients
    • Oxf
    • Russell-Jones DL, Watts GF, Weissgberger A, et al. 1994 The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients. Clin Endocrinol (Oxf), 41:345-350.
    • (1994) Clin Endocrinol , vol.41 , pp. 345-350
    • Russell-Jones, D.L.1    Watts, G.F.2    Weissgberger, A.3
  • 17
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • Rosen T, Bengtsson BA. 1990 Premature mortality due to cardiovascular disease in hypopituitarism. Lancet. 336:285-288.
    • (1990) Lancet , vol.336 , pp. 285-288
    • Rosen, T.1    Bengtsson, B.A.2
  • 18
    • 0027473333 scopus 로고
    • Continuous subcutaneous infusions of growth hormone (GH) releasing hormone 1-44 for 14 days increase GH and insulin-like growth factor-I levels in old men
    • Corpas E, Harman SM, Pineyro MA, Roberson R, Blackman MR. 1993 Continuous subcutaneous infusions of growth hormone (GH) releasing hormone 1-44 for 14 days increase GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab. 76:134-138.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 134-138
    • Corpas, E.1    Harman, S.M.2    Pineyro, M.A.3    Roberson, R.4    Blackman, M.R.5
  • 20
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers CY, Momany FA, Reynolds GA, Hong A. 1984 On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology. 114:1537-1545.
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.A.2    Reynolds, G.A.3    Hong, A.4
  • 21
    • 0024384514 scopus 로고
    • Effect of a new synthetic hexapeptide to selectively stimulate growth hormone release in healthy human subjects
    • Ilson BE, Jorkasky DK, Curnow RT, Stote RM. 1989 Effect of a new synthetic hexapeptide to selectively stimulate growth hormone release in healthy human subjects. J Clin Endocrinol Metab. 69:212-214.
    • (1989) J Clin Endocrinol Metab , vol.69 , pp. 212-214
    • Ilson, B.E.1    Jorkasky, D.K.2    Curnow, R.T.3    Stote, R.M.4
  • 22
    • 0025267776 scopus 로고
    • Growth Hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone
    • Bowers CY, Reynolds GA, Durham D, Barrera CM, Pezzoli SS, Thorner MO. 1990 Growth Hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab. 70:975-982.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 975-982
    • Bowers, C.Y.1    Reynolds, G.A.2    Durham, D.3    Barrera, C.M.4    Pezzoli, S.S.5    Thorner, M.O.6
  • 23
    • 0025809717 scopus 로고
    • On the actions of the growth hormone-releasing hexapeptide, GHRP
    • Bowers CY, Sartor AO, Reynolds GA, Badger TM. 1991 On the actions of the growth hormone-releasing hexapeptide, GHRP. Endocrinology. 128: 2027-2035.
    • (1991) Endocrinology , vol.128 , pp. 2027-2035
    • Bowers, C.Y.1    Sartor, A.O.2    Reynolds, G.A.3    Badger, T.M.4
  • 24
    • 0026534533 scopus 로고
    • The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration
    • Bowers CY, Alster DK, Frentz JM. 1992 The growth hormone-releasing activity of a synthetic hexapeptide in normal men and short statured children after oral administration. J Clin Endocrinol Metab. 74:292-298.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 292-298
    • Bowers, C.Y.1    Alster, D.K.2    Frentz, J.M.3
  • 25
    • 0026647332 scopus 로고
    • Oral administration of growth hormone (GH)-releasing peptide (GHRP) stimulates GH secretion in normal men
    • Hartman ML, Farello G, Pezzoli SS, Thorner MO. 1992 Oral administration of growth hormone (GH)-releasing peptide (GHRP) stimulates GH secretion in normal men. J Clin Endocrinol Metab. 74:1378-1384.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1378-1384
    • Hartman, M.L.1    Farello, G.2    Pezzoli, S.S.3    Thorner, M.O.4
  • 26
    • 0025740899 scopus 로고
    • Growth hormone secretion during continuous infusion of growth hormone releasing peptide (GHRP): Partial response attenuation
    • DeBell WK, Pezzoli SS, Thorner MO. 1991 Growth hormone secretion during continuous infusion of growth hormone releasing peptide (GHRP): partial response attenuation. J Clin Endocrinol Metab. 72:1312-1316.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 1312-1316
    • DeBell, W.K.1    Pezzoli, S.S.2    Thorner, M.O.3
  • 27
    • 0027278470 scopus 로고
    • 24-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus
    • Huhn WC, Hartman ML, Pezzoli SS, Thorner MO. 1993 24-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus. J Clin Endocrinol Metab. 76:1202-1208.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1202-1208
    • Huhn, W.C.1    Hartman, M.L.2    Pezzoli, S.S.3    Thorner, M.O.4
  • 28
    • 0027248530 scopus 로고
    • A nonpeptidyl growth hormone secretagogue
    • Smith RG, Cheng K, Schoen WR, et al. 1993 A nonpeptidyl growth hormone secretagogue. Science. 260:1640-1643.
    • (1993) Science , vol.260 , pp. 1640-1643
    • Smith, R.G.1    Cheng, K.2    Schoen, W.R.3
  • 29
    • 0028033954 scopus 로고
    • Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects
    • Aloi JA, Gertz BJ, Hartman ML, et al. 1994 Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects. J Clin Endocrinol Metab. 79:943-949.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 943-949
    • Aloi, J.A.1    Gertz, B.J.2    Hartman, M.L.3
  • 30
    • 0027435282 scopus 로고
    • Growth hormone response in man to L-692,429, a novel nonpeptide mimic of growth hormone releasing peptide (GHRP-6)
    • Gertz BJ, Barrett JS, Eisenhandler R, et al. 1993 Growth hormone response in man to L-692,429, a novel nonpeptide mimic of growth hormone releasing peptide (GHRP-6). J Clin Endocrinol Metab. 77:1393-1397.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1393-1397
    • Gertz, B.J.1    Barrett, J.S.2    Eisenhandler, R.3
  • 31
    • 0028270653 scopus 로고
    • Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women
    • Chapman IM, Hartman ML, Straume M, Johnson ML, Veldhuis JD, Thorner MO. 1994 Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women. J Clin Endocrinol Metab. 78:1312-1319.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1312-1319
    • Chapman, I.M.1    Hartman, M.L.2    Straume, M.3    Johnson, M.L.4    Veldhuis, J.D.5    Thorner, M.O.6
  • 32
    • 0028826366 scopus 로고
    • Differential impact of age, sexsteroid hormones, and obesity on basal vs. pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay
    • Veldhuis JD, Liem AY, South S, et al. 1995 Differential impact of age, sexsteroid hormones, and obesity on basal vs. pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay. J Clin Endocrinol Metab. 80:3209-3222.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3209-3222
    • Veldhuis, J.D.1    Liem, A.Y.2    South, S.3
  • 33
    • 0028219557 scopus 로고
    • Low basal and persistent pulsatile growth hormone secretion are revealed in normal and hyposomatotropic men studied with a new ultrasensitive chemiluminescence assay
    • Iranmanesh A, Grisso B, Veldhuis JD. 1994 Low basal and persistent pulsatile growth hormone secretion are revealed in normal and hyposomatotropic men studied with a new ultrasensitive chemiluminescence assay. J Clin Endocrinol Metab. 78:526-535.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 526-535
    • Iranmanesh, A.1    Grisso, B.2    Veldhuis, J.D.3
  • 34
    • 0026529796 scopus 로고
    • Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two day fast in normal men
    • Hartman ML, Veldhuis JD, Johnson ML, et al. 1992 Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two day fast in normal men. J Clin Endocrinol Metab. 74:757-765.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 757-765
    • Hartman, M.L.1    Veldhuis, J.D.2    Johnson, M.L.3
  • 35
    • 0002339027 scopus 로고
    • Evolution of deconvolution analysis as a hormone pulse detection method
    • Johnson ML, Veldhuis JD. 1995 Evolution of deconvolution analysis as a hormone pulse detection method. Methods Neurosci. 28:1-24.
    • (1995) Methods Neurosci , vol.28 , pp. 1-24
    • Johnson, M.L.1    Veldhuis, J.D.2
  • 36
    • 0023448602 scopus 로고
    • The pituitary gland secretes in bursts: Appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations
    • Veldhuis JD, Carlson ML, Johnson ML. 1987 The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations. Proc Natl Acad Sci USA. 84:7686-7690.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7686-7690
    • Veldhuis, J.D.1    Carlson, M.L.2    Johnson, M.L.3
  • 38
    • 0028359763 scopus 로고
    • The insulin-like growth factor I generation test: Resistance to growth hormone with aging and estrogen replacement therapy
    • Lieberman SA, Mitchell AM, Marcus R, Hintz RL, Huffman AR. 1994 The insulin-like growth factor I generation test: resistance to growth hormone with aging and estrogen replacement therapy. Horm Metab Res. 26:229-233.
    • (1994) Horm Metab Res , vol.26 , pp. 229-233
    • Lieberman, S.A.1    Mitchell, A.M.2    Marcus, R.3    Hintz, R.L.4    Huffman, A.R.5
  • 39
    • 0023818534 scopus 로고
    • Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. I. An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin
    • Koch BD, Blalock JB, Schonbrunn A. 1988 Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. I. An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin. J Biol Chem. 263:216-225.
    • (1988) J Biol Chem , vol.263 , pp. 216-225
    • Koch, B.D.1    Blalock, J.B.2    Schonbrunn, A.3
  • 40
    • 0027457091 scopus 로고
    • Mechanisms of action of a second generation growth hormone releasing peptide in rat anterior pituitary cells
    • Ackman MS, Girard M, O'Brien LF, Ho AK, Chik CL. 1993 Mechanisms of action of a second generation growth hormone releasing peptide in rat anterior pituitary cells. Endocrinology. 132:1286-1291.
    • (1993) Endocrinology , vol.132 , pp. 1286-1291
    • Ackman, M.S.1    Girard, M.2    O'Brien, L.F.3    Ho, A.K.4    Chik, C.L.5
  • 41
    • 0026607276 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide, GH-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors
    • Goth MI, Lyons CE, Canny BJ, Thomer MO. 1992 Pituitary adenylate cyclase activating polypeptide, GH-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology. 130:939-944.
    • (1992) Endocrinology , vol.130 , pp. 939-944
    • Goth, M.I.1    Lyons, C.E.2    Canny, B.J.3    Thomer, M.O.4
  • 42
    • 0028983836 scopus 로고
    • Central actions of peptide and non-peptide growth hormone secretagogues in the rat
    • Dickson SL, Leng G, Dyball REJ, Smith RG. 1995 Central actions of peptide and non-peptide growth hormone secretagogues in the rat. Neuroendocrinology. 61:36-43.
    • (1995) Neuroendocrinology , vol.61 , pp. 36-43
    • Dickson, S.L.1    Leng, G.2    Dyball, R.E.J.3    Smith, R.G.4
  • 44
    • 84995256367 scopus 로고
    • Evaluation of pulsatile patterns of growth hormone release in humans: A brief review
    • Hartman ML, Iranmanesh A, Thorner MO, Veldhuis JD. 1993 Evaluation of pulsatile patterns of growth hormone release in humans: a brief review. Am J Hum Biol. 5:603-614.
    • (1993) Am J Hum Biol , vol.5 , pp. 603-614
    • Hartman, M.L.1    Iranmanesh, A.2    Thorner, M.O.3    Veldhuis, J.D.4


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