Overexpression of a dominant negative GIP receptor in transgenic mice results in disturbed postnatal pancreatic islet and beta-cell development

Regulatory Peptides

Volumn 125, Issue 1-3, 2005, Pages 103-117

  Herbach, Nadja ^a   Goeke, Burkhard ^b   Schneider, Marlon ^c   Hermanns, Walter ^a   Wolf, Eckhard ^c   Wanke, Ruediger ^a  

^a Institute of Veterinary Pathology   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c Inst Molec Anim Breed/Gene Ctr   (Germany)

Author keywords

Diabetes mellitus; GIP; GIPR; Incretin hormones; Transgenic mice

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GASTRIC INHIBITORY POLYPEPTIDE; GLUCOSE; INSULIN; PANCREAS HORMONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DIABETOGENESIS; FEMALE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE URINE LEVEL; HORMONAL REGULATION; INSULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PERINATAL PERIOD; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; SPECIES COMPARISON; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, NEWBORN; AREA UNDER CURVE; BLOOD GLUCOSE; BODY WEIGHT; DNA; DNA, COMPLEMENTARY; FEMALE; GENES, DOMINANT; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; GLUCOSE TOLERANCE TEST; IMMUNOHISTOCHEMISTRY; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, TRANSGENIC; PANCREAS; PEPTIDE FRAGMENTS; PHENOTYPE; POLYMERASE CHAIN REACTION; PROINSULIN; PROMOTER REGIONS (GENETICS); PROTEIN PRECURSORS; RECEPTORS, GASTROINTESTINAL HORMONE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 9944251348     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2004.08.021     Document Type: Article

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