Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway

Journal of Biological Chemistry

Volumn 277, Issue 40, 2002, Pages 37088-37097

  Ehses, Jan A ^a,b   Pelech, Steven L ^a   Pederson, Raymond A ^a   McIntosh, Christopher H S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Kinexus Bioinformatics Corporation   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; GLUCOSE; INSULIN; SCREENING;

SIGNAL TRANSDUCTION;

POLYPEPTIDES;

ADENYLATE CYCLASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GLUCOSE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RAF PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME REGULATION; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GASTRIC INHIBITORY POLYPEPTIDE; GLUCOSE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF; RAP1 GTP-BINDING PROTEINS; RATS; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 0037020242     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205055200     Document Type: Article

References (58)

1. Fehmann, H.-C., Göke, R., and Göke, B. (1995) Endocr. Rev. 16, 390-410
2. Pederson, R. (1994) in Gut Peptides: Biochemistry and Physiology (Walsh, J., and Dockray, G., eds) pp. 217-259, Raven Press, Ltd., New York
3. Kieffer, T. J., and Habener, J. F. (1999) Endocr. Rev. 20, 876-913
4. Usdin, T., Mezey, É., Button, D., Brownstein, M., and Bonner, T. (1993) Endocrinology 133, 2861-2870
5. Wheeler, M., Gelling, R., McIntosh, C., Georgiou, J., Brown, J., and Pederson, R. (1995) Endocrinology 136, 4629-4639
6. Gremlich, S., Porret, A., Hani, E., Cherif, D., Vionnet, N., Froguel, P., and Thorens, B. (1995) Diabetes 44, 1202-1208
7. Weiss, J. (1998) Pharmacol. Ther. 80, 231-264
8. Barrie, A. P., Clohessy, A. M., Buensuceso, C. S., Rogers, M. V., and Allen, J. M. (1997) J. Biol. Chem. 272, 19666-19671
9. Jiang, Y., Cypress, A. M., Muse, E. D., Wu, C.-R., Unson, C. G., Merrifield, R. B., and Sakmar, T. P. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 10102-10107
10. Frodin, M., Sekine, N., Roche, E., Filloux, C., Prentki, M., Wollheim, C. B., and Oberghen, E. V. (1995) J. Biol. Chem. 270, 7882-7889
11. Montrose-Rafizadeh, C., Avdonin, P., Garant, M. J., Rodgers, B. D., Kole, S., Yang, H., Levine, M. A., Schwindinger, W., Bernier, M. (1999) Endocrinology 140, 1132-1140
12. Yamaguchi, T., Pelling, J. C., Ramaswamy, N. T., Eppler, J. W., Wallace, D. P., Nagao, S., Rome, L. A., Sullivan, L. P., and Grantham, J. J. (2000) Kidney Int. 57, 1460-1471
13. Kubota, A., Yamada, Y., Yasuda, K., Someya, Y., Ihara, Y., Kagimoto, S., Watanabe, R., Kuroe, A., Ishida, H., and Seino, Y. (1997) Biochem. Biophys. Res. Commun. 235, 171-175
14. Trumper, A., Trumper, K., Trusheim, H., Arnold, R., Goke, B., and Horsch, D. (2001) Mol. Endocrinol. 15, 1559-1570
15. Garrington, T. P., and Johnson, G. L. (1999) Curr. Opin. Cell Biol. 11, 211-218
16. Pearson, G., Robinson, F., Gibson, T. B., Xu, B., Karandikar, M., Berman, K., and Cobb, M. H. (2001) Endocr. Rev. 22, 153-183
17. Chen, Z., Gibson, T. B., Robinson, F., Silvestro, L., Pearson, G., Xu, B., Wright, A., Vanderbilt, C., and Cobb, M. H. (2001) Chem. Rev. 101, 2449-2476
18. Chang, L., and Karin, M. (2001) Nature 410, 37-40
19. Marinissen, M. J., and Gutkind, J. S. (2001) Trends Pharmacol. Sci. 22, 368-376
20. Liebmann, C. (2001) Cell. Signal. 13, 777-785
21. Gutkind, J. S. (1998) J. Biol. Chem. 273, 1839-1842
22. Daaka, Y., Luttrell, L. M., and Lefkowitz, R. J. (1997) Nature 390, 88-91
23. Maudsley, S., Pierce, K. L., Zamah, A. M., Miller, W. E., Ahn, S., Daaka, Y., Lefkowitz, R. J., and Luttrell, L. M. (2000) J. Biol. Chem. 275, 9572-9580
24. Ma, Y.-C., Huang, J., Ali, S., Lowry, W., and Huang, X.-Y. (2000) Cell 102, 635-646
25. Hui, H., Wright, C., and Perfetti, R. (2001) Diabetes 50, 785-796
26. Kawasaki, H., Springett, G. M., Mochizuki, N., Toki, S., Nakaya, M., Matsuda, M., Houseman, D. E., and Graybiel, A. M. (1998) Science 282, 2275-2279
27. Altschuler, D. L., Peterson, S. N., Ostrowski, M. C., and Lapetina, E. G. (1995) J. Biol. Chem. 270, 10373-10376
28. Ohmstede, C.-A., Farrell, F. X., Reep, B. R., Clemetson, K. J., and Lapetina, E. G. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 6527-6531
29. Richards, J. S. (2001) Mol. Endocrinol. 15, 209-218
30. Houslay, M. D., and Kolch, W. (2000) Mol. Pharmacol. 58, 659-668
31. Vossler, M. R., Yao, H., York, R. D., Pan, M.-G., Rim, C. S., and Stork, P. J. S. (1997) Cell 89, 73-82
32. York, R. D., Yao, H., Dillon, T., Ellig, C. L., Eckert, S. P., McCleskey, E. W., and Stork, P. J. (1998) Nature 392, 622-626
33. Gelling, R., Wheeler, M., Xue, J., Gyomorey, S., Nian, C., Pederson, R., and McIntosh, C. (1997) Endocrinology 138, 2640-2643
34. Efrat, S., Linde, S., Kofod, H., Spector, D., Delannoy, M., Grant, S., Hanahan, D., and Baekkeskov, S. (1988) Cell Biol. 85, 9037-9041
35. Hohmeier, H. E., Mulder, H., Chen, G., Henkel-Rieger, R., Prentki, M., and Newgard, C. B. (2000) Diabetes 49, 424-430
36. Pelech, S. L., Sutter, C., and Zhang, H. (2002) in Methods in Molecular Medicine Series (Terrian, D., ed), Humana Press Inc., Totowa, NJ
37. Khoo, S., and Cobb, M. H. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5599-55604
38. Ehses, J., Lee, S. T., Pederson, R. A., and McIntosh, C. H. S. (2001) J. Biol. Chem. 276, 23667-23673
39. Zimmerman, S., and Moelling, K. (1999) Science 286, 1741-1744
40. Kolch, W. (2000) Biochem. J. 351, 289-305
41. Dhillon, A. S., Meikle, S., Yazici, Z., Eulitz, M., and Kolch, W. (2002) EMBO J. 21, 64-71
42. Kubicek, M., Pacher, M., Abraham, Q. D., Podar, K., Eulitz, M., and Baccarini, M. (2002) J. Biol. Chem. 277, 7913-7919
43. Ohtsuka, T., Shimizu, K., Yamamori, B., Kuroda, S., and Takai, Y. (1996) J. Biol. Chem. 271, 1258-1261
44. Schmitt, J. M., and Stork, P. J. (2002) Mol. Cell 9, 85-94
45. Buteau, J., Foisy, S., Rhodes, C. J., Carpenter, L., Biden, T. J., and Prentki, M. (2001) Diabetes 50, 2237-2243
46. Jones, P. M., and Persaud, S. J. (1998) Endocr. Rev. 19, 429-461
47. Wu, J., Dent, P., Jelinek, T., Wolfman, A., Weber, M. J., and Sturgill, T. W. (1993) Science 262, 1065-1069
48. Dhillon, A. S., Pollock, C., Steen, H., Shaw, P. E., Mischak, H., and Kolch, W. (2002) Mol. Cell. Biol. 22, 3237-3246
49. Mischak, H., Seitz, T., Janosch, P., Eulitz, M., Steen, H., Schellerer, M., Philipp, A., and Kolch, W. (1996) Mol. Cell. Biol. 16, 5409-5418
50. Qiu, W., Zhuang, S., Lintig, F. C. V., Boss, G. R., and Pilz, R. B. (2000) J. Biol. Chem. 275, 31921-31929
51. Seidel, M. G., Klinger, M., Freissmuth, M., and Hoeller, C. (1999) J. Biol. Chem. 274, 25833-25841
52. Schmitt, J. M., and Stork, P. J. (2000) J. Biol. Chem. 275, 25342-25350
53. Guo, F.-F., Kumahara, E., and Saffen, D. (2001) J. Biol. Chem. 276, 25568-25581
54. Stevetson, B. R., Kong, X., and Lawrence, J. C. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10305-10309
55. Verheijen, M. H. G., and Defize, L. H. K. (1997) J. Biol. Chem. 272, 3423-3429
56. Ehses, J. A., Casilla, V., Doty, T., Pospisilik, J. A., Demuth, H. U., Pederson, R. A., and McIntosh, C. H. S. (2002) Diabetes 51, A339
57. Xu, G., Stoffers, D. A., Habener, J. F., and Bonner-Weir, S. (1999) Diabetes 48, 2270-2276
58. Tourrel, C., Bailbe, D., Meile, M.-J., Kergoat, M., and Portha, B. (2001) Diabetes 50, 1562-1570