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Volumn 23, Issue 6, 2002, Pages 1001-1008

A safer vaccine for Alzheimer's disease?

Author keywords

Alzheimer's disease; Amyloid ; Central nervous system; Immunization; Therapy

Indexed keywords

VACCINE;

EID: 0036862013     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(02)00124-0     Document Type: Article
Times cited : (49)

References (56)
  • 1
    • 0035106780 scopus 로고    scopus 로고
    • Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
    • Bacskai B.J., Kajdasz S.T., Christie R.H., Carter C., Games D., Seubert P.et al. Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat. Med. 7(3):2001;369-372.
    • (2001) Nat. Med. , vol.7 , Issue.3 , pp. 369-372
    • Bacskai, B.J.1    Kajdasz, S.T.2    Christie, R.H.3    Carter, C.4    Games, D.5    Seubert, P.6
  • 2
    • 0033835996 scopus 로고    scopus 로고
    • Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
    • Bard F., Cannon C., Barbour R., Burke R.L., Games D., Grajeda H.et al. Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 6(8):2000;916-919.
    • (2000) Nat. Med. , vol.6 , Issue.8 , pp. 916-919
    • Bard, F.1    Cannon, C.2    Barbour, R.3    Burke, R.L.4    Games, D.5    Grajeda, H.6
  • 3
    • 0026181914 scopus 로고
    • Alzheimer's disease from the perspective of the systemic and localized forms of amyloidosis
    • Castano E.M., Frangione B. Alzheimer's disease from the perspective of the systemic and localized forms of amyloidosis. Brain Pathol. 1(4):1991;263-271.
    • (1991) Brain Pathol. , vol.1 , Issue.4 , pp. 263-271
    • Castano, E.M.1    Frangione, B.2
  • 4
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-Abeta antibody alters CNS and plasma Abeta clearance and decreases brain Abeta burden in a mouse model of Alzheimer's disease
    • DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. Peripheral anti-Abeta antibody alters CNS and plasma Abeta clearance and decreases brain Abeta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 2001.
    • (2001) Proc Natl Acad Sci USA
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.C.4    Paul, S.M.5    Holtzman, D.M.6
  • 5
    • 0035845614 scopus 로고    scopus 로고
    • Reduced levels of amyloid beta-peptide antibody in Alzheimer disease
    • Du Y., Dodel R., Hampel H., Buerger K., Lin S., Eastwood B.et al. Reduced levels of amyloid beta-peptide antibody in Alzheimer disease. Neurology. 57(5):2001;801-805.
    • (2001) Neurology , vol.57 , Issue.5 , pp. 801-805
    • Du, Y.1    Dodel, R.2    Hampel, H.3    Buerger, K.4    Lin, S.5    Eastwood, B.6
  • 6
    • 0034718206 scopus 로고    scopus 로고
    • Approaches to discovery and characterization of inhibitors of amyloid β-peptide polymerization
    • Findeis M.A. Approaches to discovery and characterization of inhibitors of amyloid β-peptide polymerization. Biochim. Biophys. Acta. 1502(1):2000;76-84.
    • (2000) Biochim. Biophys. Acta , vol.1502 , Issue.1 , pp. 76-84
    • Findeis, M.A.1
  • 7
    • 0033103657 scopus 로고    scopus 로고
    • High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation
    • Frenkel D., Balass M., Katchalski-Katzir E., Solomon B. High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation. J. Neuroimmunol. 95(1/2):1999;136-142.
    • (1999) J. Neuroimmunol , vol.95 , Issue.1-2 , pp. 136-142
    • Frenkel, D.1    Balass, M.2    Katchalski-Katzir, E.3    Solomon, B.4
  • 8
    • 0032145617 scopus 로고    scopus 로고
    • N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies
    • Frenkel D., Balass M., Solomon B. N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies. J. Neuroimmunol. 88(1/2):1998;85-90.
    • (1998) J. Neuroimmunol. , vol.88 , Issue.1-2 , pp. 85-90
    • Frenkel, D.1    Balass, M.2    Solomon, B.3
  • 9
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
    • Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C.et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature. 373(6514):1995;523-527.
    • (1995) Nature , vol.373 , Issue.6514 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3    Barbour, R.4    Berthelette, P.5    Blackwell, C.6
  • 10
    • 0027410894 scopus 로고
    • Human antibodies reactive with beta-amyloid protein in Alzheimer's disease
    • Gaskin F., Finley J., Fang Q., Xu S., Fu S.M. Human antibodies reactive with beta-amyloid protein in Alzheimer's disease. J. Exp. Med. 177(4):1993;1181-1186.
    • (1993) J. Exp. Med. , vol.177 , Issue.4 , pp. 1181-1186
    • Gaskin, F.1    Finley, J.2    Fang, Q.3    Xu, S.4    Fu, S.M.5
  • 11
    • 0034573291 scopus 로고    scopus 로고
    • Piecing together Alzheimer's
    • George-Hyslop P.H. Piecing together Alzheimer's. Sci. Am. 283(6):2000;76-83.
    • (2000) Sci. Am. , vol.283 , Issue.6 , pp. 76-83
    • George-Hyslop, P.H.1
  • 12
    • 0033810109 scopus 로고    scopus 로고
    • Antibody-mediated resolution of light chain-associated amyloid deposits
    • [in process citation]
    • Hrncic R., Wall J., Wolfenbarger D.A., Murphy C.L., Schell M., Weiss D.T.et al. Antibody-mediated resolution of light chain-associated amyloid deposits. Am. J. Pathol. 157(4):2000;1239-1246. [in process citation].
    • (2000) Am. J. Pathol. , vol.157 , Issue.4 , pp. 1239-1246
    • Hrncic, R.1    Wall, J.2    Wolfenbarger, D.A.3    Murphy, C.L.4    Schell, M.5    Weiss, D.T.6
  • 13
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits Aβ elevation, and amyloid plaques in transgenic mice
    • Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S.et al. Correlative memory deficits Aβ elevation, and amyloid plaques in transgenic mice. Science. 274(5284):1996;99-102.
    • (1996) Science , vol.274 , Issue.5284 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6
  • 16
    • 0023984742 scopus 로고
    • The antigenic index: A novel algorithm for predicting antigenic determinants
    • Jameson B.A., Wolf H. The antigenic index: a novel algorithm for predicting antigenic determinants. Comput. Appl. Biosci. 4(1):1988;181-186.
    • (1988) Comput. Appl. Biosci. , vol.4 , Issue.1 , pp. 181-186
    • Jameson, B.A.1    Wolf, H.2
  • 17
    • 0034700471 scopus 로고    scopus 로고
    • Ab peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    • Janus C., Pearson J., McLaurin J., Mathews P.M., Jiang Y., Schmidt S.D.et al. Ab peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature. 408(6815):2000;979-982.
    • (2000) Nature , vol.408 , Issue.6815 , pp. 979-982
    • Janus, C.1    Pearson, J.2    McLaurin, J.3    Mathews, P.M.4    Jiang, Y.5    Schmidt, S.D.6
  • 18
    • 0027258525 scopus 로고
    • The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
    • Jarrett J.T., Berger E.P., Lansbury P.T.J. The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry. 32(18):1993;4693-4697.
    • (1993) Biochemistry , vol.32 , Issue.18 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.J.3
  • 19
    • 0035082722 scopus 로고    scopus 로고
    • Amyloid β40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice
    • Ji Y., Permanne B., Sigurdsson E.M., Holtzman D.M., Wisniewski T. Amyloid β40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice. J. Alzheimer's Dis. 3(1):2001;23-30.
    • (2001) J. Alzheimer's Dis. , vol.3 , Issue.1 , pp. 23-30
    • Ji, Y.1    Permanne, B.2    Sigurdsson, E.M.3    Holtzman, D.M.4    Wisniewski, T.5
  • 20
    • 0034657130 scopus 로고    scopus 로고
    • Evidence for seeding of beta-amyloid by intracerebral infusion of Alzheimer brain extracts in beta-amyloid precursor protein-transgenic mice
    • Kane M.D., Lipinski W.J., Callahan M.J., Bian F., Durham R.A., Schwarz R.D.et al. Evidence for seeding of beta-amyloid by intracerebral infusion of Alzheimer brain extracts in beta-amyloid precursor protein-transgenic mice. J. Neurosci. 20(10):2000;3606-3611.
    • (2000) J. Neurosci. , vol.20 , Issue.10 , pp. 3606-3611
    • Kane, M.D.1    Lipinski, W.J.2    Callahan, M.J.3    Bian, F.4    Durham, R.A.5    Schwarz, R.D.6
  • 21
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid β protein in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Kawarabayashi T., Younkin L.H., Saido T.C., Shoji M., Ashe K.H., Younkin S.G. Age-dependent changes in brain, CSF, and plasma amyloid β protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21(2):2001;372-381.
    • (2001) J. Neurosci. , vol.21 , Issue.2 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5    Younkin, S.G.6
  • 22
    • 0030613755 scopus 로고    scopus 로고
    • Prion (PrPSc)-specific epitope defined by a monoclonal antibody
    • Korth C., Stierli B., Streit P., Moser M., Schaller O., Fischer R.et al. Prion (PrPSc)-specific epitope defined by a monoclonal antibody. Nature. 390(6655):1997;74-77.
    • (1997) Nature , vol.390 , Issue.6655 , pp. 74-77
    • Korth, C.1    Stierli, B.2    Streit, P.3    Moser, M.4    Schaller, O.5    Fischer, R.6
  • 23
    • 0034183020 scopus 로고    scopus 로고
    • Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease
    • Kuo Y.M., Crawford F., Mullan M., Kokjohn T.A., Emmerling M.R., Weller R.O.et al. Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease. Mol. Med. 6(5):2000;430-439.
    • (2000) Mol. Med. , vol.6 , Issue.5 , pp. 430-439
    • Kuo, Y.M.1    Crawford, F.2    Mullan, M.3    Kokjohn, T.A.4    Emmerling, M.R.5    Weller, R.O.6
  • 24
    • 0031961832 scopus 로고    scopus 로고
    • Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid β peptide in aged squirrel monkey with cerebral amyloid angiopathy
    • Mackic J.B., Weiss M.H., Miao W., Kirkman E., Ghiso J., Calero M.et al. Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid β peptide in aged squirrel monkey with cerebral amyloid angiopathy. J. Neurochem. 70(1):1998;210-215.
    • (1998) J. Neurochem. , vol.70 , Issue.1 , pp. 210-215
    • Mackic, J.B.1    Weiss, M.H.2    Miao, W.3    Kirkman, E.4    Ghiso, J.5    Calero, M.6
  • 25
    • 0028054008 scopus 로고
    • Passage of human amyloid β-protein 1-40 across the murine blood-brain barrier
    • Maness L.M., Banks W.A., Podlisny M.B., Selkoe D.J., Kastin A.J. Passage of human amyloid β-protein 1-40 across the murine blood-brain barrier. Life Sci. 55(21):1994;1643-1650.
    • (1994) Life Sci. , vol.55 , Issue.21 , pp. 1643-1650
    • Maness, L.M.1    Banks, W.A.2    Podlisny, M.B.3    Selkoe, D.J.4    Kastin, A.J.5
  • 26
    • 0029870240 scopus 로고    scopus 로고
    • Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs
    • Martel C.L., Mackic J.B., McComb J.G., Ghiso J., Zlokovic B.V. Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs. Neurosci. Lett. 206(2/3):1996;57-160.
    • (1996) Neurosci. Lett. , vol.206 , Issue.2-3 , pp. 57-160
    • Martel, C.L.1    Mackic, J.B.2    McComb, J.G.3    Ghiso, J.4    Zlokovic, B.V.5
  • 28
    • 84984755327 scopus 로고    scopus 로고
    • Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
    • Morgan D., Diamond D.M., Gottschall P.E., Ugen K.E., Dickey C., Hardy J.et al. Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature. 408(6815):2000;982-985.
    • (2000) Nature , vol.408 , Issue.6815 , pp. 982-985
    • Morgan, D.1    Diamond, D.M.2    Gottschall, P.E.3    Ugen, K.E.4    Dickey, C.5    Hardy, J.6
  • 29
    • 0016840819 scopus 로고
    • Radioimmunoassays for Ig classes G, A, M, D, and E in spinal fluids: Normal values of different age groups
    • Nerenberg S.T., Prasad R. Radioimmunoassays for Ig classes G, A, M, D, and E in spinal fluids: normal values of different age groups. J. Lab. Clin. Med. 86(5):1975;887-898.
    • (1975) J. Lab. Clin. Med. , vol.86 , Issue.5 , pp. 887-898
    • Nerenberg, S.T.1    Prasad, R.2
  • 30
    • 0033596944 scopus 로고    scopus 로고
    • Recognition sequence design for peptidyl modulators of β-amyloid aggregation and toxicity
    • Pallitto M.M., Ghanta J., Heinzelman P., Kiessling L.L., Murphy R.M. Recognition sequence design for peptidyl modulators of β-amyloid aggregation and toxicity. Biochemistry. 38(12):1999;3570-3578.
    • (1999) Biochemistry , vol.38 , Issue.12 , pp. 3570-3578
    • Pallitto, M.M.1    Ghanta, J.2    Heinzelman, P.3    Kiessling, L.L.4    Murphy, R.M.5
  • 31
    • 0027447286 scopus 로고
    • Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
    • Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., Cotman C.W. Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13(4):1993;1676-1687.
    • (1993) J. Neurosci. , vol.13 , Issue.4 , pp. 1676-1687
    • Pike, C.J.1    Burdick, D.2    Walencewicz, A.J.3    Glabe, C.G.4    Cotman, C.W.5
  • 32
    • 0035968932 scopus 로고    scopus 로고
    • Amyloid beta peptide as a vaccine for Alzheimer's disease involves receptor-mediated transport at the blood-brain barrier
    • Poduslo J.F., Curran G.L. Amyloid beta peptide as a vaccine for Alzheimer's disease involves receptor-mediated transport at the blood-brain barrier. Neuroreport. 12(15):2001;3197-3200.
    • (2001) Neuroreport , vol.12 , Issue.15 , pp. 3197-3200
    • Poduslo, J.F.1    Curran, G.L.2
  • 33
    • 0030716309 scopus 로고    scopus 로고
    • Permeability and residual plasma volume of human, Dutch variant, and rat amyloid β-protein 1-40 at the blood-brain barrier
    • Poduslo J.F., Curran G.L., Haggard J.J., Biere A.L., Selkoe D.J. Permeability and residual plasma volume of human, Dutch variant, and rat amyloid β-protein 1-40 at the blood-brain barrier. Neurobiol. Dis. 4(1):1997;27-34.
    • (1997) Neurobiol. Dis. , vol.4 , Issue.1 , pp. 27-34
    • Poduslo, J.F.1    Curran, G.L.2    Haggard, J.J.3    Biere, A.L.4    Selkoe, D.J.5
  • 34
    • 0032995727 scopus 로고    scopus 로고
    • Receptor-mediated transport of human amyloid β-protein 1-40 and 1-42 at the blood-brain barrier
    • Poduslo J.F., Curran G.L., Sanyal B., Selkoe D.J. Receptor-mediated transport of human amyloid β-protein 1-40 and 1-42 at the blood-brain barrier. Neurobiol. Dis. 6(3):1999;190-199.
    • (1999) Neurobiol. Dis. , vol.6 , Issue.3 , pp. 190-199
    • Poduslo, J.F.1    Curran, G.L.2    Sanyal, B.3    Selkoe, D.J.4
  • 35
    • 0034870813 scopus 로고    scopus 로고
    • Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease
    • Poduslo J.F., Curran G.L., Wengenack T.M., Malester B., Duff K. Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 8(4):2001;555-567.
    • (2001) Neurobiol. Dis. , vol.8 , Issue.4 , pp. 555-567
    • Poduslo, J.F.1    Curran, G.L.2    Wengenack, T.M.3    Malester, B.4    Duff, K.5
  • 36
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T.et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 400(6740):1999;173-177.
    • (1999) Nature , vol.400 , Issue.6740 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3    Gordon, G.4    Grajeda, H.5    Guido, T.6
  • 37
    • 0034521392 scopus 로고    scopus 로고
    • Clearance of Alzheimer's amyloid-β(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
    • Shibata M., Yamada S., Kumar S.R., Calero M., Bading J., Frangione B.et al. Clearance of Alzheimer's amyloid-β(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J. Clin. Invest. 106(12):2000;1489-1499.
    • (2000) J. Clin. Invest. , vol.106 , Issue.12 , pp. 1489-1499
    • Shibata, M.1    Yamada, S.2    Kumar, S.R.3    Calero, M.4    Bading, J.5    Frangione, B.6
  • 38
    • 0031457782 scopus 로고    scopus 로고
    • Bilateral injections of amyloid-β 25-35 into the amygdala of young Fischer rats: Behavioral, neurochemical, and time dependent histopathological effects
    • Sigurdsson E.M., Lee J.M., Dong X.W., Hejna M.J., Lorens S.A. Bilateral injections of amyloid-β 25-35 into the amygdala of young Fischer rats: behavioral, neurochemical, and time dependent histopathological effects. Neurobiol. Aging. 18(6):1997;591-608.
    • (1997) Neurobiol. Aging , vol.18 , Issue.6 , pp. 591-608
    • Sigurdsson, E.M.1    Lee, J.M.2    Dong, X.W.3    Hejna, M.J.4    Lorens, S.A.5
  • 39
    • 0030292993 scopus 로고    scopus 로고
    • Local and distant histopathological effects of unilateral amyloid-beta 25-35 injections into the amygdala of young F344 rats
    • Sigurdsson E.M., Lorens S.A., Hejna M.J., Dong X.W., Lee J.M. Local and distant histopathological effects of unilateral amyloid-beta 25-35 injections into the amygdala of young F344 rats. Neurobiol. Aging. 17(6):1996;893-901.
    • (1996) Neurobiol. Aging , vol.17 , Issue.6 , pp. 893-901
    • Sigurdsson, E.M.1    Lorens, S.A.2    Hejna, M.J.3    Dong, X.W.4    Lee, J.M.5
  • 41
    • 0034884382 scopus 로고    scopus 로고
    • Immunization with a non-toxic/non-fibrillar amyloid-β homologous peptide reduces Alzheimer's disease associated pathology in transgenic mice
    • Sigurdsson E.M., Scholtzova H., Mehta P.D., Frangione B., Wisniewski T. Immunization with a non-toxic/non-fibrillar amyloid-β homologous peptide reduces Alzheimer's disease associated pathology in transgenic mice. Am. J. Pathol. 159(2):2001;439-447.
    • (2001) Am. J. Pathol. , vol.159 , Issue.2 , pp. 439-447
    • Sigurdsson, E.M.1    Scholtzova, H.2    Mehta, P.D.3    Frangione, B.4    Wisniewski, T.5
  • 42
    • 0031012176 scopus 로고    scopus 로고
    • Neuroautoimmunity: Pathogenic implications for Alzheimer's disease
    • Singh V.K. Neuroautoimmunity: pathogenic implications for Alzheimer's disease. Gerontology. 43(1/2):1997;79-94.
    • (1997) Gerontology , vol.43 , Issue.1-2 , pp. 79-94
    • Singh, V.K.1
  • 44
    • 0030058382 scopus 로고    scopus 로고
    • Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer β-amyloid peptide
    • Solomon B., Koppel R., Hanan E., Katzav T. Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer β-amyloid peptide. Proc. Natl. Acad. Sci. U.S.A. 93(1):1996;452-455.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , Issue.1 , pp. 452-455
    • Solomon, B.1    Koppel, R.2    Hanan, E.3    Katzav, T.4
  • 45
    • 0030600371 scopus 로고    scopus 로고
    • Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation
    • Soto C., Kindy M.S., Baumann M., Frangione B. Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochem. Biophys. Res. Commun. 226(3):1996;672-680.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , Issue.3 , pp. 672-680
    • Soto, C.1    Kindy, M.S.2    Baumann, M.3    Frangione, B.4
  • 46
    • 0031873102 scopus 로고    scopus 로고
    • β-Sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy
    • Soto C., Sigurdsson E.M., Morelli L., Kumar R.A., Castano E.M., Frangione B. β-Sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nat. Med. 4(7):1998;822-826.
    • (1998) Nat. Med. , vol.4 , Issue.7 , pp. 822-826
    • Soto, C.1    Sigurdsson, E.M.2    Morelli, L.3    Kumar, R.A.4    Castano, E.M.5    Frangione, B.6
  • 47
    • 0020726355 scopus 로고
    • Cerebrospinal fluid proteins: III. Normal values of immunoglobulins G, A and M (variations related to race, sex and age)
    • Vermes L.M. Cerebrospinal fluid proteins: III. Normal values of immunoglobulins G, A and M (variations related to race, sex and age). Arq. Neuropsiquiatr. 41(1):1983;25-49.
    • (1983) Arq. Neuropsiquiatr. , vol.41 , Issue.1 , pp. 25-49
    • Vermes, L.M.1
  • 48
    • 0033520461 scopus 로고    scopus 로고
    • Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
    • Walsh D.M., Hartley D.M., Kusumoto Y., Fezoui Y., Condron M.M., Lomakin A.et al. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J. Biol. Chem. 274(36):1999;25945-25952.
    • (1999) J. Biol. Chem. , vol.274 , Issue.36 , pp. 25945-25952
    • Walsh, D.M.1    Hartley, D.M.2    Kusumoto, Y.3    Fezoui, Y.4    Condron, M.M.5    Lomakin, A.6
  • 49
    • 0033133360 scopus 로고    scopus 로고
    • The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation
    • Webster S.D., Tenner A.J., Poulos T.L., Cribbs D.H. The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation. Neurobiol. Aging. 20(3):1999;297-304.
    • (1999) Neurobiol. Aging , vol.20 , Issue.3 , pp. 297-304
    • Webster, S.D.1    Tenner, A.J.2    Poulos, T.L.3    Cribbs, D.H.4
  • 50
    • 0033801852 scopus 로고    scopus 로고
    • Nasal administration of amyloid-β peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
    • Weiner H.L., Lemere C.A., Maron R., Spooner E.T., Grenfell T.J., Mori C.et al. Nasal administration of amyloid-β peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease. Ann. Neurol. 48(4):2000;567-579.
    • (2000) Ann. Neurol. , vol.48 , Issue.4 , pp. 567-579
    • Weiner, H.L.1    Lemere, C.A.2    Maron, R.3    Spooner, E.T.4    Grenfell, T.J.5    Mori, C.6
  • 51
    • 0019841683 scopus 로고
    • Fact and speculation on the function of immune response genes in antigen presentation
    • Werdelin O. Fact and speculation on the function of immune response genes in antigen presentation. Scand. J. Immunol. 14(6):1981;623-629.
    • (1981) Scand. J. Immunol. , vol.14 , Issue.6 , pp. 623-629
    • Werdelin, O.1
  • 52
    • 0031461082 scopus 로고    scopus 로고
    • Biology of A beta amyloid in Alzheimer's disease (published erratum appears in Neurobiol Dis 1998 July; 5(1):65)
    • Wisniewski T., Ghiso J., Frangione B. Biology of A beta amyloid in Alzheimer's disease (published erratum appears in Neurobiol Dis 1998 July; 5(1):65). Neurobiol. Dis. 4(5):1997;313-328.
    • (1997) Neurobiol. Dis. , vol.4 , Issue.5 , pp. 313-328
    • Wisniewski, T.1    Ghiso, J.2    Frangione, B.3
  • 53
    • 0030925824 scopus 로고    scopus 로고
    • Increased incidence of anti-beta-amyloid autoantibodies secreted by Epstein-Barr virus transformed B cell lines from patients with Alzheimer's disease
    • Xu S., Gaskin F. Increased incidence of anti-beta-amyloid autoantibodies secreted by Epstein-Barr virus transformed B cell lines from patients with Alzheimer's disease. Mech. Ageing Dev. 94(1/3):1997;213-222.
    • (1997) Mech. Ageing Dev. , vol.94 , Issue.1-3 , pp. 213-222
    • Xu, S.1    Gaskin, F.2
  • 54
    • 0024472693 scopus 로고
    • Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease
    • Yankner B.A., Dawes L.R., Fisher S., Villa-Komaroff L., Oster-Granite M.L., Neve R.L. Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science. 245(4916):1989;417-420.
    • (1989) Science , vol.245 , Issue.4916 , pp. 417-420
    • Yankner, B.A.1    Dawes, L.R.2    Fisher, S.3    Villa-Komaroff, L.4    Oster-Granite, M.L.5    Neve, R.L.6
  • 55
    • 0030628788 scopus 로고    scopus 로고
    • Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology
    • Zlokovic B. Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology. Neurobiol. Dis. 4(1):1997;23-26.
    • (1997) Neurobiol. Dis. , vol.4 , Issue.1 , pp. 23-26
    • Zlokovic, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.